9NIX image
Deposition Date 2025-02-26
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
9NIX
Keywords:
HYDROLASE/HYDROLASE INHIBITOR
Title:
FphI, Staphylococcus aureus fluorophosphonate-binding serine hydrolases I, in complex with Carbamoyl Fluoride compound 21
Biological Source:
Source Organism(s):
Staphylococcus aureus USA300-0114 (Taxon ID: 1385527)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.42 Å
R-Value Free:
0.18
R-Value Work:
0.17
R-Value Observed:
0.17
Space Group:
P 21 21 21
9NIX validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Serine aminopeptidase S33 dom
Gene (Uniprot):SAOUHSC_00417
Chain IDs:A
Chain Length:247
Number of Molecules:1
Biological Source:Staphylococcus aureus USA300-0114
UniProt ID:Q2G0V7 Pfam ID:PF12146
Ligand Molecules
A1BYM
CA
Primary Citation
Carbamoyl Fluorides as Novel Warheads Targeting Serine Hydrolases
To Be Published ? ? ? (?)
Primary Citation of related structures
9NIX
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