ISDA: 9N7T

Deposition Date 2025-02-06

Release Date 2026-02-18

Last Version Date 2026-02-18

Entry Detail

PDB ID:

9N7T

Keywords:

VIRAL PROTEIN/IMMUNE SYSTEM

Title:

H5 hemagglutinin (A/Jiangsu/NJ210/2023) in complex with central stem-targeting Fab ST14

Biological Source:

Source Organism(s):

Influenza A virus (Taxon ID: 11320)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.01 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:H5 HA1
Chain IDs:A, E (auth: B), I (auth: C)
Chain Length:220
Number of Molecules:3
Biological Source:Influenza A virus

UniProt ID:A0A8E4ZAK5

Polymer Type:polypeptide(L)
Molecule:ST14 Heavy Chain Fab
Chain IDs:C (auth: H), G (auth: D), K (auth: E)
Chain Length:124
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:ST14 Light Chain Fab
Chain IDs:B (auth: L), F, J (auth: G)
Chain Length:110
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:H5 HA2
Chain IDs:D (auth: a), H (auth: I), L (auth: J)
Chain Length:220
Number of Molecules:3
Biological Source:Influenza A virus

Ligand Molecules

NAG

Primary Citation

Individualized IG genotyping coupled with high throughput isolation of influenza HA-specific monoclonal antibodies

Fisher, A, Corcoran, M, Chernyshev, M, Brouwer, P.J.M, Gillespie, R, Nicoletto, A, Loeffler, J.R, Ferguson, J.A, Rodriguez, A.J, Narang, S, Adori, M, Angeletti, D, van Gils, M.J, Castro Dopico, X, Kanekiyo, M, Ward, A.B, Han, J, Karlsson Hedestam, G.B.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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