ISDA: 9MPG

Deposition Date 2024-12-30

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9MPG

Keywords:

GENE REGULATION

Title:

BRD2-BD1 in complex with cyclic peptide 2.1A

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.80 Å

R-Value Free:

0.21

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Bromodomain-containing protei
Gene (Uniprot):BRD2
Chain IDs:A, B, C, D
Chain Length:135
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P25440 Pfam ID:PF00439

Polymer Type:polypeptide(L)
Molecule:2.1A
Chain IDs:E, F
Chain Length:18
Number of Molecules:2
Biological Source:synthetic construct

Ligand Molecules

GOL

Primary Citation

BRD2-BD1 in complex with cyclic peptide 2.1A

Patel, K, Mackay, J.P, Walshe, J.L.Show

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