ISDA: 9MC5

Deposition Date 2025-03-17

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9MC5

Keywords:

CYTOSOLIC PROTEIN

Title:

Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3), Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.29 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin-like modifier-activ
Gene (Uniprot):UBA1
Chain IDs:A
Chain Length:1058
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P22314 Pfam ID:PF00899, PF16190, PF16191, PF10585, PF09358 EC:2.3.2.23

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:(E3-independent) E2 ubiquitin
Gene (Uniprot):UBE2O
Chain IDs:B
Chain Length:1292
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9C0C9 Pfam ID:PF23048, PF23046, PF23043, PF23044, PF00179 EC:2.3.2.24

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Polyubiquitin-C
Gene (Uniprot):UBC
Chain IDs:C
Chain Length:77
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P0CG48 Pfam ID:PF00240

Ligand Molecules

AMP

Primary Citation

Cryo-EM structure of Human UBA1-UBE2O-Ub -Transthiolation state 3

Chen, P.-T, Wu, K.-P.Show

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Primary Citation of related structures

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