9MC0 image
Deposition Date 2025-03-17
Release Date 2026-03-25
Last Version Date 2026-03-25
Entry Detail
PDB ID:
9MC0
Keywords:
CELL CYCLE
Title:
The co-crystal structure of DYRK2 with AF-4
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.87 Å
R-Value Free:
0.29
R-Value Work:
0.24
R-Value Observed:
0.24
Space Group:
C 1 2 1
9MC0 validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Dual specificity tyrosine-pho
Gene (Uniprot):DYRK2
Chain IDs:A (auth: B), B (auth: A)
Chain Length:387
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q92630 Pfam ID:PF00069 EC:2.7.12.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR A TYR modified residue
Ligand Molecules
A1ENX
Primary Citation
Targeting DYRK2 for the treatment of cancer
To Be Published ? ? ? (?)
Primary Citation of related structures
9MC0
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