ISDA: 9MAW

Deposition Date 2025-03-14

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9MAW

Keywords:

ISOMERASE

Title:

Crystal structure of TOPBP1BRCT7-8 domain in complex with 1-Adamantaneacetic acid

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.45 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 65 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA topoisomerase 2-binding p
Gene (Uniprot):TOPBP1
Chain IDs:A
Chain Length:231
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q92547 Pfam ID:PF00533, PF23294

Ligand Molecules

A1ENP

Primary Citation

Small-Molecule Ligand Screening and Structural Investigation of the TopBP1 BRCT 7-8 Domain

Chen, W, Wang, L, Ruan, K.Show

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