ISDA: 9LZ0

Deposition Date 2025-02-21

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9LZ0

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of PTH1R-beta-arrestin1 complex in state 1

Biological Source:

Source Organism(s):

Bos taurus (Taxon ID: 9913)
Mus musculus (Taxon ID: 10090)
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.80 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-arrestin-1
Gene (Uniprot):ARRB1
Chain IDs:A
Chain Length:393
Number of Molecules:1
Biological Source:Bos taurus

UniProt ID:P17870 Pfam ID:PF00339, PF02752

Polymer Type:polypeptide(L)
Molecule:Fab30 heavy chain
Chain IDs:B (auth: H)
Chain Length:229
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Fab30 light chain
Chain IDs:C (auth: L)
Chain Length:215
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Long-acting PTH
Chain IDs:D (auth: P)
Chain Length:36
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Parathyroid hormone/parathyro
Gene (Uniprot):PTH1R
Chain IDs:E (auth: R)
Chain Length:483
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q03431 Pfam ID:PF02793, PF00002

Modified Residue