9LV4 image
Deposition Date 2025-02-11
Release Date 2026-02-18
Last Version Date 2026-02-18
Entry Detail
PDB ID:
9LV4
Keywords:
DE NOVO PROTEIN
Title:
Cryo-EM Structure of Human Tie2/minibinder tw1102_4 helices Complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.67 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9LV4 validation report
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Minibinder tw1102
Chain IDs:B (auth: A)
Chain Length:125
Number of Molecules:1
Biological Source:synthetic construct
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Angiopoietin-1 receptor
Gene (Uniprot):TEK
Chain IDs:A (auth: B)
Chain Length:430
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q02763 Pfam ID:PF10430 EC:2.7.10.1
Ligand Molecules
NA
Primary Citation
Designed Tie2-specific minibinder with therapeutic potential
To Be Published ? ? ? (?)
Primary Citation of related structures
9LV4
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