ISDA: 9LQ5

Deposition Date 2025-01-27

Release Date 2025-11-26

Last Version Date 2025-11-26

Entry Detail

PDB ID:

9LQ5

Keywords:

IMMUNE SYSTEM/RNA

Title:

Cryo-EM structure of Apo type III-B CRISPR-Cas effector complex

Biological Source:

Source Organism(s):

Bacteroides fragilis (Taxon ID: 817)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.97 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cmr1
Gene (Uniprot):F2Z89_11915, F3B44_04900, NXW39_14635
Chain IDs:A
Chain Length:469
Number of Molecules:1
Biological Source:Bacteroides fragilis

UniProt ID:A0A5M5QTL0

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type III-B CRISPR-associated
Gene (Uniprot):cas10
Chain IDs:B
Chain Length:600
Number of Molecules:1
Biological Source:Bacteroides fragilis

UniProt ID:A0A5C6J4N7 Pfam ID:PF12469, PF22335

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:CRISPR-associated protein Cmr
Gene (Uniprot):NXW39_14645
Chain IDs:C
Chain Length:423
Number of Molecules:1
Biological Source:Bacteroides fragilis

UniProt ID:A0A9X9IKM4 Pfam ID:PF09700

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type III-B CRISPR module RAMP
Gene (Uniprot):cmr4
Chain IDs:D, E, F
Chain Length:279
Number of Molecules:3
Biological Source:Bacteroides fragilis

UniProt ID:A0A9X9NER2 Pfam ID:PF03787

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:CRISPR type III-B/RAMP module
Gene (Uniprot):CQW34_02195, F2Z29_06595, F2Z89_11935, F3B44_04880, FSA03_20630, FSA06_24400, NXW39_14655, NXX45_16700
Chain IDs:G, H
Chain Length:136
Number of Molecules:2
Biological Source:Bacteroides fragilis

UniProt ID:A0A2M9V7H9 Pfam ID:PF09701

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RAMP superfamily protein
Gene (Uniprot):cmr6
Chain IDs:I
Chain Length:314
Number of Molecules:1
Biological Source:Bacteroides fragilis

UniProt ID:A0A2M9V7I0 Pfam ID:PF03787

Polymer Type:polyribonucleotide
Molecule:crRNA
Chain IDs:J
Chain Length:49
Number of Molecules:1
Biological Source:Bacteroides fragilis

Ligand Molecules

Primary Citation

Mechanisms of SAM-AMP synthesis and degradation in antiviral type III CRISPR signaling.

Benzhen, D, Jin, X, Chen, Z, Zhao, B.Show

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Primary Citation of related structures

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