ISDA: 9LK7

Deposition Date 2025-01-16

Release Date 2025-08-20

Last Version Date 2026-03-04

Entry Detail

PDB ID:

9LK7

Keywords:

STRUCTURAL PROTEIN

Title:

Cryo-EM Structure of GAT3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sodium- and chloride-dependen
Gene (Uniprot):SLC6A11
Chain IDs:A
Chain Length:632
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P48066 Pfam ID:PF00209

Ligand Molecules

Primary Citation

Substrate and inhibitor binding of human GABA transporter 3.

Xu, H, Zhang, Y, Bai, Q, He, L, Chen, Q, Qiu, Y, Li, R, Yu, J, Zhao, J, Zhao, Y.Show

Structure 33 2049 2057.e5 (2025)

PMID: 40914153 DOI: 10.1016/j.str.2025.08.012

Primary Citation of related structures

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