ISDA: 9JO1

Deposition Date 2024-09-24

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9JO1

Keywords:

DNA

Title:

NMR Solution structure of the 2:1 Berberine-BLM-G4 Complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

100

Conformers Submitted:

Selection Criteria:

structures with the lowest energy

Download Validation Report

Macromolecular Entities

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*TP*GP*AP*GP*GP*GP*
Chain IDs:A (auth: X)
Chain Length:21
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

BER

Primary Citation

BLM G-quadruplex stabilizers synergize with PARP inhibitor to kill BRCA wild-type colon cancer cells

Wang, Y.Y, Bian, Y.T, Chen, X.Y, Li, J.Z, Liu, Y.S, Kong, L.Y, Wang, K.B.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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