9IGT image
Deposition Date 2025-02-20
Release Date 2026-03-11
Last Version Date 2026-03-11
Entry Detail
PDB ID:
9IGT
Keywords:
RIBOSOME
Title:
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
5.96 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9IGT validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S34, mi
Gene (Uniprot):MRPS34
Chain IDs:Z (auth: 0)
Chain Length:218
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82930 Pfam ID:PF16053
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S35, mi
Gene (Uniprot):MRPS35
Chain IDs:AA (auth: 1)
Chain Length:323
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82673 Pfam ID:PF10213
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Aurora kinase A-interacting p
Gene (Uniprot):AURKAIP1
Chain IDs:BA (auth: 3)
Chain Length:199
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9NWT8 Pfam ID:PF08213
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Pentatricopeptide repeat doma
Gene (Uniprot):PTCD3
Chain IDs:CA (auth: 4)
Chain Length:689
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q96EY7 Pfam ID:PF22330, PF13812
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Translation initiation factor
Gene (Uniprot):MTIF2
Chain IDs:FA (auth: 7)
Chain Length:691
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P46199 Pfam ID:PF00009, PF22042, PF11987
Polymer Type:polyribonucleotide
Molecule:12S mitochondrial rRNA
Chain IDs:EA (auth: A)
Chain Length:302
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S2, mit
Gene (Uniprot):MRPS2
Chain IDs:A (auth: B)
Chain Length:407
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y399 Pfam ID:PF00318
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S24, mi
Gene (Uniprot):MRPS24
Chain IDs:B (auth: C)
Chain Length:167
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q96EL2 Pfam ID:PF14955
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S5, mit
Gene (Uniprot):MRPS5
Chain IDs:C (auth: D)
Chain Length:430
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82675 Pfam ID:PF21251, PF00333, PF03719
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S6, mit
Gene (Uniprot):MRPS6
Chain IDs:D (auth: E)
Chain Length:125
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82932 Pfam ID:PF01250
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S7, mit
Gene (Uniprot):MRPS7
Chain IDs:E (auth: F)
Chain Length:242
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y2R9 Pfam ID:PF00177
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S9, mit
Gene (Uniprot):MRPS9
Chain IDs:F (auth: G)
Chain Length:396
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82933 Pfam ID:PF00380
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S10, mi
Gene (Uniprot):MRPS10
Chain IDs:G (auth: H)
Chain Length:201
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82664 Pfam ID:PF00338
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S11, mi
Gene (Uniprot):MRPS11
Chain IDs:H (auth: I)
Chain Length:194
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82912 Pfam ID:PF00411
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S12, mi
Gene (Uniprot):MRPS12
Chain IDs:I (auth: J)
Chain Length:138
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O15235 Pfam ID:PF00164
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S14, mi
Gene (Uniprot):MRPS14
Chain IDs:J (auth: K)
Chain Length:128
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O60783 Pfam ID:PF00253
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S15, mi
Gene (Uniprot):MRPS15
Chain IDs:K (auth: L)
Chain Length:257
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82914 Pfam ID:PF00312
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S16, mi
Gene (Uniprot):MRPS16
Chain IDs:L (auth: M)
Chain Length:137
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y3D3 Pfam ID:PF00886
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S17, mi
Gene (Uniprot):MRPS17
Chain IDs:M (auth: N)
Chain Length:130
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y2R5 Pfam ID:PF00366
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S18b, m
Gene (Uniprot):MRPS18B
Chain IDs:N (auth: O)
Chain Length:258
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y676 Pfam ID:PF01084
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S18c, m
Gene (Uniprot):MRPS18C
Chain IDs:O (auth: P)
Chain Length:142
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y3D5 Pfam ID:PF01084
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:MRPS21 isoform 1
Gene (Uniprot):MRPS21
Chain IDs:P (auth: Q)
Chain Length:87
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:A0A2J8VEN6 Pfam ID:PF01165
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S22, mi
Gene (Uniprot):MRPS22
Chain IDs:Q (auth: R)
Chain Length:360
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82650 Pfam ID:PF10245
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S23, mi
Gene (Uniprot):MRPS23
Chain IDs:R (auth: S)
Chain Length:190
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y3D9 Pfam ID:PF10484
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S25, mi
Gene (Uniprot):MRPS25
Chain IDs:S (auth: T)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P82663 Pfam ID:PF05047
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S26, mi
Gene (Uniprot):MRPS26
Chain IDs:T (auth: U)
Chain Length:205
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9BYN8 Pfam ID:PF14943
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S27, mi
Gene (Uniprot):MRPS27
Chain IDs:U (auth: V)
Chain Length:414
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q92552 Pfam ID:PF10037
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S28, mi
Gene (Uniprot):MRPS28
Chain IDs:V (auth: W)
Chain Length:187
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y2Q9 Pfam ID:PF10246
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S29, mi
Gene (Uniprot):DAP3
Chain IDs:W (auth: X)
Chain Length:398
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P51398 Pfam ID:PF10236
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S31, mi
Gene (Uniprot):MRPS31
Chain IDs:X (auth: Y)
Chain Length:395
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q92665 Pfam ID:PF15433
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:28S ribosomal protein S33, mi
Gene (Uniprot):MRPS33
Chain IDs:Y (auth: Z)
Chain Length:106
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y291 Pfam ID:PF08293
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Putative ribosome-binding fac
Gene (Uniprot):RBFA
Chain IDs:HA (auth: a)
Chain Length:302
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8N0V3 Pfam ID:PF02033
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:12S rRNA N4-methylcytidine (m
Gene (Uniprot):METTL15
Chain IDs:DA (auth: b)
Chain Length:407
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:A6NJ78 Pfam ID:PF01795
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Large ribosomal subunit prote
Gene (Uniprot):MRPL12
Chain IDs:GA (auth: t)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P52815 Pfam ID:PF00542
Ligand Molecules
ATP
FES
GDP
MG
NAD
SPM
ZN
Primary Citation
Structural analysis reveals alternative pathways for assembly of the human mitoribosome small subunit
To Be Published ? ? ? (?)
Primary Citation of related structures
9IGT
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