ISDA: 9HNT

Deposition Date 2024-12-11

Release Date 2025-12-24

Last Version Date 2025-12-24

Entry Detail

PDB ID:

9HNT

Keywords:

MEMBRANE PROTEIN

Title:

a5b3 GABAAR bound to Etomidate, GABA, and Mb25 in a desensitized state in saposin nanodiscs

Biological Source:

Source Organism(s):

Aequorea victoria (Taxon ID: 6100)
Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)

Expression System(s):

Homo sapiens, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.32 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,Gam
Gene (Uniprot):GABRA5, GFP
Chain IDs:A, D
Chain Length:679
Number of Molecules:2
Biological Source:Aequorea victoria, Homo sapiens

UniProt ID:P42212,P31644 Pfam ID:PF01353, PF02931, PF02932

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Gamma-aminobutyric acid recep
Gene (Uniprot):GABRB3
Chain IDs:B, C, E
Chain Length:623
Number of Molecules:3
Biological Source:Homo sapiens, Aequorea victoria

UniProt ID:P28472 Pfam ID:PF02931, PF02932

Polymer Type:polypeptide(L)
Molecule:Megabody 25
Chain IDs:F (auth: P)
Chain Length:541
Number of Molecules:1
Biological Source:Escherichia coli

Ligand Molecules