9E9W image
Deposition Date 2024-11-08
Release Date 2026-03-18
Last Version Date 2026-03-18
Entry Detail
PDB ID:
9E9W
Keywords:
VIRAL PROTEIN,HYDROLASE/INHIBITOR
Title:
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with S217622
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.48 Å
R-Value Free:
0.22
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 1 21 1
9E9W validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:3C-like proteinase nsp5
Gene (Uniprot):rep
Mutagens:M49I
Chain IDs:A, B
Chain Length:299
Number of Molecules:2
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTD1 Pfam ID:PF05409 EC:2.7.7.48
Ligand Molecules
7YY
Primary Citation
Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with S217622
To Be Published ? ? ? (?)
Primary Citation of related structures
9E9W
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