9E0F image
Deposition Date 2024-10-17
Release Date 2026-02-18
Last Version Date 2026-02-18
Entry Detail
PDB ID:
9E0F
Keywords:
DNA BINDING PROTEIN
Title:
A focus of DNMT tetramer (1) of the cryo-EM structure of human DNMT3A2-DNMT3B3 complex bound to di-nucleosome
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.46 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9E0F validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA (cytosine-5)-methyltransf
Gene (Uniprot):DNMT3A
Chain IDs:C (auth: U), D (auth: Y)
Chain Length:689
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9Y6K1 Pfam ID:PF00855, PF17980, PF21255, PF00145 EC:2.1.1.37
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Isoform 3 of DNA (cytosine-5)
Gene (Uniprot):DNMT3B
Chain IDs:A (auth: V), B (auth: Z)
Chain Length:773
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q9UBC3 Pfam ID:PF00855, PF17980, PF21255, PF00145 EC:2.1.1.37
Ligand Molecules
SAH
ZN
Primary Citation
The structure basis for de novo DNA methylation in chromatin
To Be Published ? ? ? (?)
Primary Citation of related structures
9E00
9E05
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