ISDA: 9DPG

Deposition Date 2024-09-21

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9DPG

Keywords:

OXIDOREDUCTASE/SUBSTRATE/INTERMEDIATE

Title:

Structure of PmHMGR bound to mevalonate, CoA and NAD 2 minutes 20 seconds after reaction initiation at pH 9

Biological Source:

Source Organism(s):

Pseudomonas sp. 'mevalonii' (Taxon ID: 32044)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.50 Å

R-Value Free:

0.23

R-Value Work:

0.18

R-Value Observed:

0.19

Space Group:

I 41 3 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:3-hydroxy-3-methylglutaryl-co
Gene (Uniprot):mvaA
Chain IDs:A, B
Chain Length:428
Number of Molecules:2
Biological Source:Pseudomonas sp. 'mevalonii'

UniProt ID:P13702 EC:1.1.1.88

Ligand Molecules

A1AFY

COA

MEV

NAI

SO4

ZKE

Primary Citation

Watching Pseudomonas mevalonii HMG-CoA Reductase in Action

Patel, H, Purohit, V, Steussy, C.S, Stauffacher, C.V, Helquist, P, Wiest, O, Schmidt, T, Rushton, P.Show

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