ISDA: 9AXW

Deposition Date 2024-03-06

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9AXW

Keywords:

IMMUNE SYSTEM

Title:

Nanobody NbJRI bound to yeast Pdc1

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae (Taxon ID: 4932)
Vicugna pacos (Taxon ID: 30538)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.30 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:branched-chain-2-oxoacid deca
Chain IDs:A (auth: AA1), B (auth: BA1), C (auth: CA1), D (auth: DA1), E (auth: EA1), F (auth: FA1), G (auth: GA1), H (auth: HA1)
Chain Length:573
Number of Molecules:8
Biological Source:Saccharomyces cerevisiae

Polymer Type:polypeptide(L)
Molecule:NbJRi
Chain IDs:I, J, K, L, M (auth: N), N (auth: O), O (auth: P), P (auth: M)
Chain Length:152
Number of Molecules:8
Biological Source:Vicugna pacos

Ligand Molecules

Primary Citation

Nanobody-mediated inhibition of yeast pyruvate decarboxylase by active site denaturation

Carrasco-Lopez, C, Gonzalez, C.L, Avalos, J.L, Afonine, P.V, Grosse-Kunstleve, R.W, Echols, N, Headd, J.J, Moriarty, N.W, Mustyakimov, M, Terwilliger, T.C, Urzhumtsev, A, Zwart, P.H, Adams, P.D, Liebschner, D, Afonine, P.V, Baker, M.L, Bunkoczi, G, Chen, V.B, Croll, T.I, Hintze, B, Hung, L.W, Jain, S, McCoy, A.J, Moriarty, N.W, Oeffner, R.D, Poon, B.K, Prisant, M.G, Read, R.J, Richardson, J.S, Richardson, D.C, Sammito, M.D, Sobolev, O.V, Stockwell, D.H, Terwilliger, T.C, Urzhumtsev, A.G, Videau, L.L, Williams, C.J, Adams, P.D.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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