ISDA: 8YF3

Deposition Date 2024-02-23

Release Date 2025-09-03

Last Version Date 2026-03-18

Entry Detail

PDB ID:

8YF3

Keywords:

TRANSFERASE

Title:

DNA cytosine C5-carboxymethyltransferase in complex with Cx-SAM

Biological Source:

Source Organism(s):

Synechococcus phage S-B43 (Taxon ID: 2484638)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.90 Å

R-Value Free:

0.26

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Cytosine-specific methyltrans
Chain IDs:A
Chain Length:372
Number of Molecules:1
Biological Source:Synechococcus phage S-B43

UniProt ID:A0A514ABG7 Pfam ID:PF00145

Ligand Molecules

GEK

Primary Citation

Carboxymethylcytosine is a natural base modification and a handle for bacteriophage DNA hypermodification.

Yang, Q, Zhang, L, Liang, Y, Ma, H, Song, L, Luo, L, Tan, J, Hu, Y, Ma, K, Chen, Y, Tong, Y, Zhang, C, Zhao, S, Wang, M, Zhang, L, Wei, Y, Zhang, Y.Show

Nat Commun 17 281 281 (2025)

PMID: 41354841 DOI: 10.1038/s41467-025-66999-9

Primary Citation of related structures

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