ISDA: 8V0J

Deposition Date 2023-11-17

Release Date 2025-08-20

Last Version Date 2026-03-04

Entry Detail

PDB ID:

8V0J

Keywords:

BIOSYNTHETIC PROTEIN

Title:

Structure of the complex between Human LIAS and H-protein in the presence of s-adenosyl-l-methionine

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.58 Å

R-Value Free:

0.23

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Lipoyl synthase, mitochondria
Gene (Uniprot):LIAS
Chain IDs:A (auth: C), B (auth: A), C (auth: B)
Chain Length:368
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:O43766 Pfam ID:PF16881, PF04055

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Glycine cleavage system H pro
Gene (Uniprot):GCSH
Chain IDs:D (auth: F), E (auth: D), F (auth: E)
Chain Length:173
Number of Molecules:3
Biological Source:Homo sapiens

UniProt ID:P23434 Pfam ID:PF01597 EC:1.4.1.27

Ligand Molecules