ISDA: 8SYK

Deposition Date 2023-05-25

Release Date 2025-02-19

Last Version Date 2026-03-04

Entry Detail

PDB ID:

8SYK

Keywords:

RNA

Title:

Crystal structure of RNA device 43 truncation mutant 3 (U100C), holo state

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.06 Å

R-Value Free:

0.25

R-Value Work:

0.22

R-Value Observed:

0.22

Space Group:

P 43 21 2

Download Validation Report

Macromolecular Entities

Polymer Type:polyribonucleotide
Molecule:RNA device 43 truncation muta
Chain IDs:A, B, C, D
Chain Length:107
Number of Molecules:4
Biological Source:synthetic construct

Ligand Molecules

GTP

TAC

Primary Citation

Structural investigation of an RNA device that regulates PD-1 expression in mammalian cells.

Stagno, J.R, Deme, J.C, Dwivedi, V, Lee, Y.T, Lee, H.K, Yu, P, Chen, S.Y, Fan, L, Degenhardt, M.F.S, Chari, R, Young, H.A, Lea, S.M, Wang, Y.X.Show

Nucleic Acids Res. 53 ? ? (2025)

PMID: 40071935 DOI: 10.1093/nar/gkaf156

Primary Citation of related structures

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