ISDA: 8G48

Deposition Date 2023-02-08

Release Date 2024-02-21

Last Version Date 2026-04-01

Entry Detail

PDB ID:

8G48

Keywords:

HYDROLASE

Title:

FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, unbound, dimer crystal form 3

Biological Source:

Source Organism(s):

Staphylococcus aureus subsp. aureus USA300 (Taxon ID: 1385529)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.95 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 2 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fluorophosphonate-binding ser
Gene (Uniprot):SAUSA300_2518
Chain IDs:A
Chain Length:279
Number of Molecules:1
Biological Source:Staphylococcus aureus subsp. aureus USA300

UniProt ID:Q2FDS6 Pfam ID:PF00561

Primary Citation

Unique structural and ligand-binding properties of the Staphylococcus aureus serine hydrolase FphE.

Jo, J, Upadhyay, T, You, X, Bennett, J.M, Lee, H, Bogyo, M, Fellner, M.Show

Proc.Natl.Acad.Sci.USA 123 e2532683123 e2532683123 (2026)

PMID: 41875159 DOI: 10.1073/pnas.2532683123

Primary Citation of related structures

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