ISDA: 7QU8

Deposition Date 2022-01-17

Release Date 2022-09-28

Last Version Date 2024-11-13

Entry Detail

PDB ID:

7QU8

Keywords:

IMMUNE SYSTEM

Title:

ADGRG3/GPR97 Extracellular Region

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.37 Å

R-Value Free:

0.31

R-Value Work:

0.26

Space Group:

P 43 21 2

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Adhesion G protein-coupled re
Gene (Uniprot):ADGRG3
Chain IDs:A, B, C, D
Chain Length:272
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q86Y34 Pfam ID:PF01825

Ligand Molecules

Primary Citation

GPR97-mediated PAR2 transactivation via a mPR3-associated macromolecular complex induces inflammatory activation of human neutrophils

Chu, T.Y, Zheng-Gerard, C, Huang, K.Y, Chang, Y.C, Chen, Y.W, Yi, K.Y, Lo, Y.L, Chiang, N.Y, Chen, H.Y, Stacey, M, Gordon, S, Tseng, W.Y, Sun, C.Y, Wu, Y.M, Pan, Y.S, Huang, C.H, Lin, C.Y, Chen, T.C, El Omari, K, Antonelou, M, Henderson, S.R, Salama, A, Seiradake, E, Lin, H.H.Show

Nat Commun ? ? ? (2022)

Primary Citation of related structures

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