ISDA: 6VRD

Deposition Date 2020-02-07

Release Date 2021-02-10

Last Version Date 2023-11-15

Entry Detail

PDB ID:

6VRD

Keywords:

HYDROLASE/RNA

Title:

Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.30 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.19

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ribonuclease H1
Gene (Uniprot):RNASEH1
Mutagens:D210N
Chain IDs:A
Chain Length:294
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O60930 Pfam ID:PF01693, PF00075 EC:3.1.26.4

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*UP*GP*GP*CP*GP*AP*
Chain IDs:B
Chain Length:20
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*(OMC)P*(N7X)P*(T39
Chain IDs:C
Chain Length:20
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules