4MY1 image
Deposition Date 2013-09-26
Release Date 2014-01-01
Last Version Date 2026-03-25
Entry Detail
PDB ID:
4MY1
Title:
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ames complexed with P68
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.60 Å
R-Value Free:
0.25
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 1
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Inosine-5'-monophosphate dehy
Mutagens:CBS domain (residues 92-220) is replaced with GG
Chain IDs:A, B, C, D, E, F, G, H
Chain Length:384
Number of Molecules:8
Biological Source:Bacillus anthracis
Primary Citation
A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity.
J.Biol.Chem. 290 5893 5911 (2015)
PMID: 25572472 DOI: 10.1074/jbc.M114.619767
Primary Citation of related structures
Feedback Form
Name
Email
Institute
Feedback