ISDA: 29HN

Deposition Date 2026-03-12

Release Date 2026-04-01

Last Version Date 2026-04-01

Entry Detail

PDB ID:

29HN

Keywords:

VIRAL PROTEIN

Title:

Crystal structure of Zika virus NS2B-NS3 protease determined via sulfur phasing

Biological Source:

Source Organism(s):

Zika virus (Taxon ID: 64320)

Expression System(s):

Escherichia coli bl21

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.77 Å

R-Value Free:

0.26

R-Value Work:

0.21

R-Value Observed:

0.22

Space Group:

P 43 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Serine protease subunit NS2B
Chain IDs:A
Chain Length:46
Number of Molecules:1
Biological Source:Zika virus

UniProt ID:Q32ZE1 Pfam ID:PF01002, PF00949 EC:2.7.7.48

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Serine protease NS3
Chain IDs:B
Chain Length:168
Number of Molecules:1
Biological Source:Zika virus

UniProt ID:Q32ZE1 Pfam ID:PF01002, PF00949 EC:2.7.7.48

Primary Citation

Crystal structure of Zika virus NS2B-NS3 protease determined via sulfur phasing

Marples, P.G, Duman, R, Ebrahim, A, Chinn, C.A, Cooper, M.R, Keates, T, V.Chandran, A, Ni, X, Wang, S, Williams, E, Koekemoer, L, Fairhead, M, Wagner, A, Shotton, E.J, Aschenbrenner, J.C, von Delft, F.Show

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