ISDA: 24OS

Deposition Date 2026-03-13

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

24OS

Keywords:

TRANSCRIPTION

Title:

Crystal Structure of BRD3 BD1 domain in complex with small molecule inhibitor IBET-762

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.83 Å

R-Value Free:

0.31

R-Value Work:

0.24

R-Value Observed:

0.25

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Bromodomain-containing protei
Gene (Uniprot):BRD3
Chain IDs:A, B
Chain Length:122
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q15059 Pfam ID:PF00439

Ligand Molecules

EAM

Primary Citation

Crystal Structure of BRD3 BD1 domain in complex with small molecule inhibitor IBET-762

Jwala, N, Chandrasekhar, A, NarasimhaRao, K.Show

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