ISDA: 23XO

Deposition Date 2026-02-24

Release Date 2026-04-08

Last Version Date 2026-04-08

Entry Detail

PDB ID:

23XO

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of human sodium/proton antiporter NHE1 in complex with Rimeporide in an outward-open conformation

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.16 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Sodium/hydrogen exchanger 1
Gene (Uniprot):SLC9A1
Chain IDs:A, B
Chain Length:815
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P19634 Pfam ID:PF00999, PF16644

Ligand Molecules

A1E6E

Primary Citation

Structure and transport mechanism of the human sodium/proton antiporter NHE1

Cong, Y, Kong, F, Zhu, A, Yan, C.Show

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