ISDA: 22XK

Deposition Date 2026-01-27

Release Date 2026-03-11

Last Version Date 2026-03-18

Entry Detail

PDB ID:

22XK

Keywords:

MEMBRANE PROTEIN

Title:

MexBYB-Ka asymmetry

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa (Taxon ID: 287)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:MexBYB
Chain IDs:A (auth: B), B (auth: C), C (auth: A)
Chain Length:1049
Number of Molecules:3
Biological Source:Pseudomonas aeruginosa

Ligand Molecules

Primary Citation

Cryo-EM structures of a MexB-MexY chimeric efflux pump reveal that large open clefts are intrinsic to the MexY porter domain.

Wang, J, Tsutsumi, K, Hirose, M, Nakashima, R, Kato, T, Nishino, K, Nakagawa, A, Yamashita, E.Show

Acta Crystallogr.,Sect.F 82 83 93 (2026)

PMID: 41744473 DOI: 10.1107/S2053230X26001202

Primary Citation of related structures

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