21AH image
Deposition Date 2025-12-04
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
21AH
Keywords:
MEMBRANE PROTEIN
Title:
LY334370-bound serotonin 1F (5-HT1F) receptor
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.18 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
21AH validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:5-hydroxytryptamine receptor
Gene (Uniprot):HTR1F
Chain IDs:A (auth: R)
Chain Length:366
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P30939 Pfam ID:PF00001
Ligand Molecules
A1E2G
Primary Citation
Structural basis of LY334370 recognition and selectivity at the 5-HT 1F receptor.
Biochem.Biophys.Res.Commun. 804 153313 153313 (2026)
PMID: 41619505 DOI: 10.1016/j.bbrc.2026.153313
Primary Citation of related structures
21AH
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