1EZJ image
Deposition Date 2000-05-11
Release Date 2000-09-20
Last Version Date 2024-02-07
Entry Detail
PDB ID:
1EZJ
Keywords:
Viral protein, transferase
Title:
CRYSTAL STRUCTURE OF THE MULTIMERIZATION DOMAIN OF THE PHOSPHOPROTEIN FROM SENDAI VIRUS
Biological Source:
Source Organism(s):
Sendai virus (strain Harris) (Taxon ID: 11196)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.90 Å
R-Value Free:
0.29
R-Value Work:
0.24
R-Value Observed:
0.25
Space Group:
P 4 21 2
1EZJ validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:NUCLEOCAPSID PHOSPHOPROTEIN
Gene (Uniprot):P/V/C
Chain IDs:A
Chain Length:115
Number of Molecules:1
Biological Source:Sendai virus (strain Harris)
UniProt ID:P04859 Pfam ID:PF01806
Ligand Molecules
CA
EMC
Primary Citation
Tetrameric coiled coil domain of Sendai virus phosphoprotein.
Nat.Struct.Biol. 7 777 781 (2000)
PMID: 10966649 DOI: 10.1038/79013

Abstact

The high resolution X-ray structure of the Sendai virus oligomerization domain reveals a homotetrameric coiled coil structure with many details that are different from classic coiled coils with canonical hydrophobic heptad repeats. Alternatives to the classic knobs-into-holes packing lead to differences in supercoil pitch and diameter that allow water molecules inside the core. This open and more hydrophilic structure does not seem to be destabilized by mutations that would be expected to disrupt classic coiled coils.

Legend

Protein

Chemical

Disease

Primary Citation of related structures
1EZJ
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