ISDA: 11YC

Deposition Date 2026-03-17

Release Date 2026-03-25

Last Version Date 2026-03-25

Entry Detail

PDB ID:

11YC

Keywords:

TRANSFERASE

Title:

The structure of human Vacuolar Protein Sorting 34 catalytic domain bound to RD-II-123

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.41 Å

R-Value Free:

0.21

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 41 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 3-kinase
Gene (Uniprot):PIK3C3
Chain IDs:A (auth: B)
Chain Length:594
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8NEB9 Pfam ID:PF00613, PF00454 EC:2.7.1.137

Ligand Molecules

A1DAY

EDO

PEG

Primary Citation

The structure of human Vacuolar Protein Sorting 34 catalytic domain bound to RD-II-123

Abiodun, W.O, Litchfield, C.M, Burtch, M, Cartwright, J, Dass, R, Singleton, J.D, Doukov, T, Peterson, M.A, Moody, J.D.Show

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