11TV image
Deposition Date 2026-03-12
Release Date 2026-04-08
Last Version Date 2026-04-08
Entry Detail
PDB ID:
11TV
Keywords:
Title:
Crystal structure of alpha/beta-hydrolase macrolide esterase EstX from Escherichia coli (S102A mutant) in complex with linearized tylosin
Biological Source:
Source Organism(s):
Escherichia coli (Taxon ID: 562)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
1.65 Å
R-Value Free:
0.19
R-Value Work:
0.16
R-Value Observed:
0.16
Space Group:
P 1 21 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:alpha/beta-hydrolase macrolid
Mutagens:S102A
Chain IDs:A (auth: D), B (auth: A)
Chain Length:280
Number of Molecules:2
Biological Source:Escherichia coli
Ligand Molecules
Primary Citation
Hydration and hydrolysis define antibiotic resistance conferred by macrolide esterases
Biorxiv ? ? ? (2026)
DOI: 10.64898/2026.03.24.713787
Primary Citation of related structures
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