ISDA: 11HN

Deposition Date 2026-02-24

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

11HN

Keywords:

VIRAL PROTEIN

Title:

SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation bound to C77G12 (S2 local refinement)

Biological Source:

Source Organism(s):

Saccharomyces cerevisiae S288C (Taxon ID: 559292)
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Spike protein S2
Gene (Uniprot):S, SMT3
Chain IDs:A (auth: B), B (auth: C), C (auth: A)
Chain Length:605
Number of Molecules:3
Biological Source:Saccharomyces cerevisiae S288C, Severe acute respiratory syndrome coronavirus 2

UniProt ID:Q12306,P0DTC2 Pfam ID:PF00240, PF01601

Ligand Molecules

NAG

Primary Citation

TMPRSS2-mediated coronavirus spike activation and inhibition

McCallum, M, Case, J.B, Brown, J, Diamond, M, Veesler, D.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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