Search Count: 47
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Organism: Escherichia coli
Method: X-RAY DIFFRACTION Resolution:3.45 Å Release Date: 2014-09-10 Classification: Chaperone/Chaperone inhibitor Ligands: 3JE |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.30 Å Release Date: 2014-01-29 Classification: Chaperone/chaperone Inhibitor Ligands: GOL, WHA, MG |
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.82 Å Release Date: 2014-12-24 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2Q8 |
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.86 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: FGH |
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2QA |
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Identification Of Novel Hsp90/Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington'S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.79 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2Q9 |
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Identification Of Novel Hsp90 / Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington S Disease
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.96 Å Release Date: 2014-04-09 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: 2R6 |
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Crystal Structure Of The Human Hsp90-Alpha N-Domain Bound To The Hsp90 Inhibitor Fj1
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.65 Å Release Date: 2013-05-15 Classification: Chaperone/Chaperone Inhibitor Ligands: FJ1 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.80 Å Release Date: 2014-11-05 Classification: Chaperone/Chaperone Inhibitor Ligands: JR9 |
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: WOE |
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU5 |
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.65 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU3 |
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Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4-Fluoro-1H-Pyrazol-1-Yl)Ethoxy]-6-Methylphenyl}-N-(2,2-Difluoropropyl)-5,7-Dihydro-6H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.70 Å Release Date: 2011-04-27 Classification: Chaperone/Chaperone inhibitor Ligands: FU7, PO4 |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.39 Å Release Date: 2012-07-18 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: MES, VHA |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2011-09-14 Classification: Chaperone/Chaperone inhibitor Ligands: B2L |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.35 Å Release Date: 2011-09-14 Classification: Chaperone/Chaperone inhibitor Ligands: GOL, B2X, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.41 Å Release Date: 2012-07-18 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: VHC, MG |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.75 Å Release Date: 2011-09-14 Classification: Chaperone/Chaperone inhibitor Ligands: B2K |
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Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2011-09-14 Classification: Chaperone/Chaperone inhibitor Ligands: B2T |
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Hsp90 Alpha N-Terminal Domain In Complex With A Macrocyclic Inhibitor, Ch5164840
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.52 Å Release Date: 2012-07-18 Classification: CHAPERONE/CHAPERONE INHIBITOR Ligands: VHE |