id Protein Group IDs Positions Position Known Site Peptide IDs Mod. Peptide IDs Best Localization Evidence ID Best Localization MS/MS ID Best Localization Raw File Best Localization Scan Number Best Identification Evidence ID Best Identification MS/MS ID Best Identification Raw File Best Identification Scan Number Proteins Leading Proteins Protein Protein Names Gene Names Protein Descriptions Uniprot Localization Prob Score Diff Localization Prob A Score Diff A PEP A Score A Localization Prob B Score Diff B PEP B Score B Localization Prob C Score Diff C PEP C Score C Localization Prob D Score Diff D PEP D Score D Localization Prob E Score Diff E PEP E Score E Localization Prob F Score Diff F PEP F Score F Localization Prob G Score Diff G PEP G Score G Diagnostic peak Number of Phospho (STY) Amino Acid Sequence Window Motifs Random Match PEP Score Modified Sequence Phospho (STY) Probabilities Phospho (STY) Score Diffs Position in peptide Charge m/z Mass Error [ppm] Intensity Ratio mod/base Intensity A Intensity B Intensity C Intensity D Intensity E Intensity F Intensity G Reverse Contaminant 0 0 776 776 1731 1948 15893 9621 Mix4_TiO2_Reinj_1_3 8293 15892 9620 Mix4_TiO2_Reinj_1_3 8241 A0FGR8-6;A0FGR8;A0FGR8-2;A0FGR8-5 A0FGR8-6 A0FGR8-6 >sp|A0FGR8-6|ESYT2_HUMAN Isoform 6 of Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2;>sp|A0FGR8|ESYT2_HUMAN Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2 PE=1 SV=1;>sp|A0FGR8-2|ESYT2_HUMAN Isoform 2 of Extended synaptotagmin-2 OS=Homo sapiens GN=ESY 0.617726 0 0.0287101 -15.2117 0.00529438 74.299 0.617726 0 1.35692E-10 125.56 2 S VKEPTPSIASDIS 1.35692E-10 125.56 _EPTPpSIApSDISLPIATQELR_ EPT(0.077)PS(0.618)IAS(0.754)DIS(0.551)LPIATQELR EPT(-7.32)PS(0)IAS(3.33)DIS(0)LPIAT(-81.72)QELR 5 3 766.69372 0.22351 682240 0 0 0 682240 0 0 0 1 0 779 779 1731 1948 15892 9620 Mix4_TiO2_Reinj_1_3 8241 15892 9620 Mix4_TiO2_Reinj_1_3 8241 A0FGR8-6;A0FGR8;A0FGR8-2;A0FGR8-5 A0FGR8-6 A0FGR8-6 >sp|A0FGR8-6|ESYT2_HUMAN Isoform 6 of Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2;>sp|A0FGR8|ESYT2_HUMAN Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2 PE=1 SV=1;>sp|A0FGR8-2|ESYT2_HUMAN Isoform 2 of Extended synaptotagmin-2 OS=Homo sapiens GN=ESY 0.999999 58.6016 0.981546 17.7936 0.00529438 74.299 0.999999 58.6016 1.35692E-10 125.56 2 S PTPSIASDISLPI CK1 0.081 1.35692E-10 125.56 _EPTPSIApSDIpSLPIATQELR_ EPTPSIAS(1)DIS(1)LPIATQELR EPT(-71.86)PS(-58.6)IAS(58.6)DIS(59.1)LPIAT(-59.1)QELR 8 2 1149.5369 1.023 1599800 334620 0 0 1265200 0 0 0 2 0 782 782 1731 1948 15892 9620 Mix4_TiO2_Reinj_1_3 8241 15892 9620 Mix4_TiO2_Reinj_1_3 8241 A0FGR8-6;A0FGR8;A0FGR8-2;A0FGR8-5 A0FGR8-6 A0FGR8-6 >sp|A0FGR8-6|ESYT2_HUMAN Isoform 6 of Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2;>sp|A0FGR8|ESYT2_HUMAN Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2 PE=1 SV=1;>sp|A0FGR8-2|ESYT2_HUMAN Isoform 2 of Extended synaptotagmin-2 OS=Homo sapiens GN=ESY 0.999999 59.1004 0.999983 48.5989 0.00529438 74.299 0.999999 59.1004 1.35692E-10 125.56 2 S SIASDISLPIATQ CK1;PLK1 0.033462 1.35692E-10 125.56 _EPTPSIApSDIpSLPIATQELR_ EPTPSIAS(1)DIS(1)LPIATQELR EPT(-71.86)PS(-58.6)IAS(58.6)DIS(59.1)LPIAT(-59.1)QELR 11 2 1149.5369 1.023 1599800 334620 0 0 1265200 0 0 0 3 2 473 473 225 259 2238 1447 Mix4_InSol_Tio2_Reinj_1 4499 2238 1447 Mix4_InSol_Tio2_Reinj_1 4499 A2RRP1;A2RRP1-2 A2RRP1 A2RRP1 >sp|A2RRP1|NBAS_HUMAN Neuroblastoma-amplified sequence OS=Homo sapiens GN=NBAS PE=1 SV=2;>sp|A2RRP1-2|NBAS_HUMAN Isoform 2 of Neuroblastoma-amplified sequence OS=Homo sapiens GN=NBAS 0.999988 49.0572 0.999938 42.053 1.52877E-32 209.82 0 0 0.847986 7.46508 8.88548E-11 129.66 0.976008 16.0939 1.37669E-26 183.22 0.999988 49.0572 1.37922E-48 242.31 1 S DEGEEDSDSDYEI CK2 0.117 1.37922E-48 242.31 _AGEEDEGEEDpSDSDYEISAK_ AGEEDEGEEDS(1)DSDYEISAK AGEEDEGEEDS(49.06)DS(-49.06)DY(-146.76)EIS(-173.11)AK 11 2 1127.9052 0.034126 1176800 288170 0 0 635850 0 161610 91214 4 3 201 201 2939 3345 28028 17435 Mix4_TiO2_Reinj_1_5 2203 28026 17432 Mix4_TiO2_2_2 1463 A4D256;O60729;O60729-4;O60729-3;O60729-2 A4D256 A4D256 >sp|A4D256|CC14C_HUMAN Dual specificity protein phosphatase CDC14C OS=Homo sapiens GN=CDC14C PE=1 SV=2;>sp|O60729|CC14B_HUMAN Dual specificity protein phosphatase CDC14B OS=Homo sapiens GN=CDC14B PE=1 SV=1;>sp|O60729-4|CC14B_HUMAN Isoform 4 of Dual specifi 1 13.2291 1 12.202 0.0504763 45.843 1 13.2291 0.493382 13.229 2 S IVHFTGSDQRKQA 0.0504763 45.843 _IVHFpTGpSDQR_ IVHFT(1)GS(1)DQR IVHFT(13.23)GS(13.23)DQR 7 2 660.26269 -0.97138 148090 0 94207 0 53884 0 0 0 5 5 92 92 2068 2343 18951 11558 Mix4_TiO2_Reinj_1_3 7373 18951 11558 Mix4_TiO2_Reinj_1_3 7373 A5D8V6 A5D8V6 A5D8V6 >sp|A5D8V6|VP37C_HUMAN Vacuolar protein sorting-associated protein 37C OS=Homo sapiens GN=VPS37C PE=1 SV=1 0.499985 0 0 0 0.499985 0 0.11538 49.292 1 S AKLEKFSSALQPG 0.11538 49.292 _FpSSALQPGTLLDLLQVEGMK_ FS(0.5)S(0.5)ALQPGTLLDLLQVEGMK FS(0)S(0)ALQPGT(-42.17)LLDLLQVEGMK 2 3 743.04085 0.45747 2113500 0 0 0 2113500 0 0 0 6 5 93 93 2068 2343 18951 11558 Mix4_TiO2_Reinj_1_3 7373 18951 11558 Mix4_TiO2_Reinj_1_3 7373 A5D8V6 A5D8V6 A5D8V6 >sp|A5D8V6|VP37C_HUMAN Vacuolar protein sorting-associated protein 37C OS=Homo sapiens GN=VPS37C PE=1 SV=1 0.499985 0 0 0 0.499985 0 0.11538 49.292 1 S KLEKFSSALQPGT CHK1;PKD 0.020748 0.11538 49.292 _FpSSALQPGTLLDLLQVEGMK_ FS(0.5)S(0.5)ALQPGTLLDLLQVEGMK FS(0)S(0)ALQPGT(-42.17)LLDLLQVEGMK 3 3 743.04085 0.45747 2113500 0 0 0 2113500 0 0 0 7 7 356 356 308 351 2894 1760 Mix4_TiO2_Reinj_1_5 2854 2894 1760 Mix4_TiO2_Reinj_1_5 2854 A6ND36;A6ND36-2 A6ND36 A6ND36 >sp|A6ND36|FA83G_HUMAN Protein FAM83G OS=Homo sapiens GN=FAM83G PE=1 SV=2;>sp|A6ND36-2|FA83G_HUMAN Isoform 2 of Protein FAM83G OS=Homo sapiens GN=FAM83G 1 47.0175 0 0 1 47.0175 0.0501138 47.017 1 7.89321 0.750435 7.8932 1 12.0476 0.62655 12.048 1 S ALVKAKSVDEIAK CHK1;CK2;PKD 0.020748 0.0501138 47.017 _AKpSVDEIAK_ AKS(1)VDEIAK AKS(47.02)VDEIAK 3 2 520.75482 0.70965 334300 0 0 0 211870 0 62546 59885 8 9 10 10 52 63 532 329 Mix4_TiO2_1_5 4734 532 329 Mix4_TiO2_1_5 4734 A6NFI3 A6NFI3 A6NFI3 >sp|A6NFI3|ZN316_HUMAN Zinc finger protein 316 OS=Homo sapiens GN=ZNF316 PE=1 SV=1 0.801523 6.06799 0.801523 6.06799 0.00117951 89.677 1 S LHTTPDSPAAQLE CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00117951 89.677 _(ac)AALHTTPDpSPAAQLER_ AALHTT(0.198)PDS(0.802)PAAQLER AALHT(-34.71)T(-6.07)PDS(6.07)PAAQLER 9 2 900.41982 0.65634 34297 34297 0 0 0 0 0 0 9 12 504 504 639 735 6096 3562 Mix4_TiO2_Reinj_1_3 5646 6096 3562 Mix4_TiO2_Reinj_1_3 5646 A7MCY6 A7MCY6 A7MCY6 >sp|A7MCY6|TBKB1_HUMAN TANK-binding kinase 1-binding protein 1 OS=Homo sapiens GN=TBKBP1 PE=1 SV=1 1 93.2491 0.999998 56.1558 0.000581265 94.359 0 0 1 93.2491 4.46342E-09 131.48 0.999605 38.8029 0.212715 38.803 0.999943 47.2496 0.110006 47.25 1 S GPGRPLSPRRAFE CAMK2;CDK1;CDK2;ERK/MAPK;PKC;Proline-directed;WW GroupIV 0.001764 4.46342E-09 131.48 _AYGSELYGPGRPLpSPR_ AYGSELYGPGRPLS(1)PR AY(-131.48)GS(-128.96)ELY(-93.25)GPGRPLS(93.25)PR 14 3 600.62073 0.21427 800940 194730 0 0 501930 0 72505 31774 10 12 415 415 5594 6376 54740 33523 Mix4_TiO2_Reinj_1_3 4240 54740 33523 Mix4_TiO2_Reinj_1_3 4240 A7MCY6 A7MCY6 A7MCY6 >sp|A7MCY6|TBKB1_HUMAN TANK-binding kinase 1-binding protein 1 OS=Homo sapiens GN=TBKBP1 PE=1 SV=1 0.999738 35.8093 0.999738 35.8093 0.0898491 54.546 1 S PSPQRRSPVPPSC PKA;Proline-directed 0.042 0.0898491 54.546 _pSPVPPSCPAPQPRPPPPPPPGER_ S(1)PVPPSCPAPQPRPPPPPPPGER S(35.81)PVPPS(-35.81)CPAPQPRPPPPPPPGER 1 3 831.06991 0.15036 280270 0 0 0 280270 0 0 0 11 13 697 697 404 462 3834 2275 Mix4_TiO2_Reinj_1_5 4384 3834 2275 Mix4_TiO2_Reinj_1_5 4384 Q96HA1;A8CG34;Q96HA1-3;Q96HA1-2 Q96HA1 Q96HA1 >sp|Q96HA1|P121A_HUMAN Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens GN=POM121 PE=1 SV=2;>sp|A8CG34|P121C_HUMAN Nuclear envelope pore membrane protein POM 121C OS=Homo sapiens GN=POM121C PE=1 SV=2;>sp|Q96HA1-3|P121A_HUMAN Isoform 3 of Nucl 0.991665 23.7787 0.958234 16.6169 0.0136554 66.628 0.991665 23.7787 0.011542 68.715 1 S QATSAPSPAPKQS CK1;Proline-directed 0.05 0.011542 68.715 _APPTLQAETATKPQATSAPpSPAPK_ APPTLQAETATKPQAT(0.004)S(0.004)APS(0.992)PAPK APPT(-68.71)LQAET(-48.2)AT(-49.39)KPQAT(-23.78)S(-23.78)APS(23.78)PAPK 20 3 814.0755 0.16869 500420 147760 0 0 352660 0 0 0 12 15 1301 1301 5434 6185 53023 32410 Mix4_TiO2_Reinj_1_1 3896 53023 32410 Mix4_TiO2_Reinj_1_1 3896 B2RTY4-4;B2RTY4;B2RTY4-2;B2RTY4-5 B2RTY4-4 B2RTY4-4 >sp|B2RTY4-4|MYO9A_HUMAN Isoform 4 of Myosin-IXa OS=Homo sapiens GN=MYO9A;>sp|B2RTY4|MYO9A_HUMAN Myosin-IXa OS=Homo sapiens GN=MYO9A PE=1 SV=2;>sp|B2RTY4-2|MYO9A_HUMAN Isoform 2 of Myosin-IXa OS=Homo sapiens GN=MYO9A;>sp|B2RTY4-5|MYO9A_HUMAN Isoform 5 of M 0.805559 6.1731 0 0 0.805559 6.1731 0.00894825 65.007 1 S LGGISPSEDRRWS 0.00894825 65.007 _SLGGISPpSEDR_ SLGGIS(0.194)PS(0.806)EDR S(-65.01)LGGIS(-6.17)PS(6.17)EDR 8 2 599.261 0.024542 32987 0 0 0 32987 0 0 0 13 18 112 112 6350 7262 64070 39311 Mix4_TiO2_Reinj_1_5 5143 64069 39310 Mix4_TiO2_Reinj_1_4 5030 CON__P00761 CON__P00761 CON__P00761 >P00761 SWISS-PROT:P00761|TRYP_PIG Trypsin - Sus scrofa (Pig). P00761 0.999089 30.3994 0.635121 2.40707 1.24476 2.4071 0 0 0.999089 30.3994 0.070497 52.751 0 0 0 0 1 S SRVATVSLPRSCA GSK3 0.081 0.070497 52.751 _VATVpSLPR_ VAT(0.001)VS(0.999)LPR VAT(-30.4)VS(30.4)LPR 5 2 461.74152 0.091683 290510 0.026099 20000 0 0 270520 0 0 0 + 14 20 46 46 908 1024;1025 8709 5328 Mix4_TiO2_Reinj_1_2 3934 8724 5333 Mix4_TiO2_Reinj_1_2 5093 CON__P02662 CON__P02662 CON__P02662 >P02662 SWISS-PROT:P02662 Alpha-S1-casein - Bos taurus (Bovine). P02662 0.999994 49.9277 0.999982 45.151 2.47535E-12 144 0.956643 10.4266 1.09379 10.427 0.999994 49.9277 3.85568E-16 169.35 2 S LSKDIGSESTEDQ 3.85568E-16 169.35 _DIGpSESpTEDQAM(ox)EDIK_ DIGS(1)ES(0.425)T(0.575)EDQAMEDIK DIGS(49.93)ES(-1.31)T(1.31)EDQAMEDIK 4 2 972.34688 0.95009 1355000 367840 11879 0 975300 0 0 0 + 15 20 48 48 908 1024;1025 8724 5333 Mix4_TiO2_Reinj_1_2 5093 8724 5333 Mix4_TiO2_Reinj_1_2 5093 CON__P02662 CON__P02662 CON__P02662 >P02662 SWISS-PROT:P02662 Alpha-S1-casein - Bos taurus (Bovine). P02662 0.998186 27.406 0.603226 1.81889 2.47535E-12 144 0.521679 0 1.09379 10.427 0.998186 27.406 3.85568E-16 169.35 2 S KDIGSESTEDQAM CK2 0.117 3.85568E-16 169.35 _DIGpSEpSTEDQAMEDIK_ DIGS(1)ES(0.998)T(0.002)EDQAMEDIK DIGS(50.54)ES(27.41)T(-27.41)EDQAMEDIK 6 2 964.34943 0.46113 320550 98276 11879 0 210400 0 0 0 + 16 20 115 115 3275;6538;6747 3710;7481;7721 68429 42031 Mix4_TiO2_Reinj_2_1 4370 68394 41946 Mix4_TiO2_1_2 4927 CON__P02662 CON__P02662 CON__P02662 >P02662 SWISS-PROT:P02662 Alpha-S1-casein - Bos taurus (Bovine). P02662 1 150.255 1 182.87 1.69339E-42 235.05 1 197.685 9.51749E-26 201.05 1 191.395 9.95965E-34 228.54 1 150.255 1.25636E-12 150.26 1 159.395 6.93712E-27 213.52 1 124.329 5.06724E-13 154.07 1 S LEIVPNSAEERLH CK2 0.117 1.69339E-42 235.05 _YKVPQLEIVPNpSAEER_ YKVPQLEIVPNS(1)AEER Y(-150.26)KVPQLEIVPNS(150.26)AEER 12 2 976.47988 0.31814 156230000 33544000 857610 0 108440000 256880 6153300 6976400 + 17 21 129 129 1754;1755 1975;1976;1977;1978 16146 9778 Mix4_TiO2_Reinj_1_6 1971 16146 9778 Mix4_TiO2_Reinj_1_6 1971 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 0.988386 19.2918 0.917967 10.0841 0.0190797 59.701 0 0 0.988386 19.2918 0.00159308 95.733 0 0 0.00225332 -25.8658 0.0274796 57.323 0.861781 7.66562 0.250056 27.607 2 S LNREQLSTSEENS CK2 0.117 0.00159308 95.733 _EQLpSTpSEENSK_ EQLS(0.988)T(0.014)S(0.998)EENSK EQLS(19.29)T(-19.29)S(27.11)EENS(-50.04)K 4 2 706.25493 0.14785 4606100 538250 0 0 3750400 0 0 317520 + 18 21 131 131 1754;1755 1975;1976;1977;1978 16175 9787 Mix4_TiO2_Reinj_1_2 1894 16175 9787 Mix4_TiO2_Reinj_1_2 1894 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 0.988963 20.3436 0.977196 17.0691 0.0361639 54.865 0 0 0.988963 20.3436 0.000220067 116.32 0 0 0.869779 8.34013 0.0274796 57.323 0.977061 17.0353 0.020116 59.408 1 S REQLSTSEENSKK GSK3;NEK6 0.076 0.000220067 116.32 _EQLSTpSEENSKK_ EQLS(0.001)T(0.009)S(0.989)EENS(0.001)KK EQLS(-29.48)T(-20.34)S(20.34)EENS(-31.01)KK 6 2 730.31924 0.47033 2430700 239940 0 0 1819900 0 195750 175160 + 19 21 143 143 3249;3250;6274;6275 3683;3684;7167;7168;7169;7170 62709 38155 Mix4_TiO2_2_1 2446 62656 38130 Mix4_TiO2_Reinj_1_6 3873 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 0.989023 23.8926 0.921003 10.6665 1.70608E-08 161.7 0.989023 23.8926 6.63996E-05 128.41 0.982541 17.5034 7.24542E-13 177.81 0.890073 9.08384 0.00293448 92.408 0.894652 9.29029 8.21794E-09 158.54 0.895771 9.34208 1.36365E-05 133.95 1 S KTVDMESTEVFTK 7.24542E-13 177.81 _TVDM(ox)EpSTEVFTKK_ T(0.004)VDMES(0.989)T(0.004)EVFT(0.003)KK T(-23.89)VDMES(23.89)T(-23.89)EVFT(-25.32)KK 6 2 805.8546 0.013042 6933400 1524400 67675 0 3829500 100350 394660 1016900 + 20 21 31 31 4171 4750;4751 39774 24549 Mix4_TiO2_Reinj_1_6 4633 39788 24552 Mix4_InSol_Tio2_Reinj_1 6468 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 1 97.8951 0.999999 62.2952 0.00151341 84.426 1 97.8951 2.29087E-09 131.15 1 80.7062 4.26166E-10 136.21 1 70.3954 1.45946E-12 140.12 1 S NMAINPSKENLCS 1.45946E-12 140.12 _NM(ox)AINPpSKENLCSTFCK_ NMAINPS(1)KENLCSTFCK NMAINPS(97.9)KENLCS(-98.77)T(-97.9)FCK 7 3 703.96496 -0.38289 2608500 164170 0 0 526310 0 977550 940460 + 21 22 35 35 2050;2744 2323;3127 25971 16079 Mix4_TiO2_Reinj_1_6 4322 18753 11448 Mix4_TiO2_1_4 4093 CON__P02666 CON__P02666 CON__P02666 >P02666 SWISS-PROT:P02666 Beta-casein - Bos taurus (Bovine). P02666 1 84.4774 1 93.4503 6.11312E-43 246.55 1 91.187 2.17316E-33 222.35 1 84.4774 8.39358E-43 244.12 1 76.9447 6.44388E-21 193.91 1 85.2398 6.77698E-26 204.93 1 75.7456 1.3299E-08 119.76 1 S KIEKFQSEEQQQT CHK1;PKD 0.020748 6.11312E-43 246.55 _IEKFQpSEEQQQTEDELQDK_ IEKFQS(1)EEQQQTEDELQDK IEKFQS(84.48)EEQQQT(-84.48)EDELQDK 6 3 811.35488 0.52396 84419000 139.22 18205000 1124100 0 60429000 881460 2329300 1449800 + 22 29 138 138 653;654 751;752 6293 3749 Mix4_InSol_TiO2_1 2607 6280 3744 Mix4_InSol_Tio2_Reinj_1 3001 CON__P12763;P02765 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor;>sp|P02765|FETUA_HUMAN Alpha-2-HS-glycoprotein OS=Homo sapiens GN=AHSG PE=1 SV=1 P12763 1 76.0143 0.999999 60.9274 0.000257433 115.61 1 67.1667 4.8015E-06 139.97 1 76.0143 4.04915E-05 132.85 1 66.7758 1.14921E-08 166.35 1 S CDSSPDSAEDVRK CK1;CK2 0.081 1.14921E-08 166.35 _CDSSPDpSAEDVRK_ CDSSPDS(1)AEDVRK CDS(-84.31)S(-76.01)PDS(76.01)AEDVRK 7 2 773.29798 0.18314 3154700 373350 0 0 856310 0 958930 966120 + 23 29 316 316 2671 3040;3041 25033 15480 Mix4_TiO2_1_6 4509 25036 15483 Mix4_TiO2_Reinj_1_6 5220 CON__P12763 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor P12763 0.483255 7.16645 0.483255 7.16645 1.09741 22.846 0.0250348 -12.1415 0.776796 29.399 0.180935 -5.17109 3.63241E-32 177.73 0.481766 0 0.00011022 95.039 0 0 0 0 2 S DLRHTFSGVASVE GSK3 0.081 9.20144E-07 99.931 _HpTFpSGVASVESSSGEAFHVGK_ HT(0.476)FS(0.483)GVAS(0.266)VES(0.258)S(0.258)S(0.258)GEAFHVGK HT(6.58)FS(7.17)GVAS(-6.58)VES(-7.17)S(-7.17)S(-7.17)GEAFHVGK 4 3 760.65051 0.26944 0 0 0 0 0 0 0 0 + 24 29 320 320 2671 3040;3041 24972 15477 Mix4_TiO2_Reinj_2_1 4080 24946 15433 Mix4_TiO2_1_4 5387 CON__P12763 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor P12763 0.916703 10.4349 0.771375 7.34023 1.09741 22.846 0.409917 1.9034 0.776796 29.399 0.85466 9.23869 3.63241E-32 177.73 0.916703 10.4349 0.00011022 95.039 0 0 0 0 1 S TFSGVASVESSSG CK1;GSK3 0.081 5.27438E-39 207.78 _HTFSGVApSVESSSGEAFHVGK_ HTFS(0.083)GVAS(0.917)VESSSGEAFHVGK HT(-34.07)FS(-10.43)GVAS(10.43)VES(-56.06)S(-61.83)S(-61.83)GEAFHVGK 8 3 733.99507 -0.064597 7991200 22287 0 0 7874400 94554 0 0 + 25 29 323 323 2671 3040;3041 24955 15445 Mix4_TiO2_1_6 4452 24946 15433 Mix4_TiO2_1_4 5387 CON__P12763 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor P12763 0.996892 26.7656 0.996892 26.7656 5.27438E-39 207.78 0.0644469 -8.03494 0.776796 29.399 0.887572 9.03891 3.63241E-32 177.73 0.0162476 -14.7205 0.00011022 95.039 0 0 0 0 1 S GVASVESSSGEAF CK1 0.081 5.27438E-39 207.78 _HTFSGVASVEpSSSGEAFHVGK_ HTFSGVAS(0.001)VES(0.997)S(0.002)SGEAFHVGK HT(-62.15)FS(-37.18)GVAS(-31.28)VES(26.77)S(-26.77)S(-41.2)GEAFHVGK 11 3 733.99507 0.032706 8730000 1325100 0 0 7405000 0 0 0 + 26 29 324 324 2671 3040;3041 24942 15425 Mix4_TiO2_1_1 4709 24946 15433 Mix4_TiO2_1_4 5387 CON__P12763 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor P12763 0.494203 0 0.494203 0 5.27438E-39 207.78 0.264457 -1.9034 0.776796 29.399 0.483998 0 9.20144E-07 99.931 0.143923 -7.71402 0.00011022 95.039 0 0 0 0 1 S VASVESSSGEAFH CK1;CK2 0.117 5.27438E-39 207.78 _HTFSGVASVESpSSGEAFHVGK_ HTFSGVASVES(0.011)S(0.494)S(0.494)GEAFHVGK HT(-46.16)FS(-39.88)GVAS(-32.8)VES(-16.42)S(0)S(0)GEAFHVGK 12 3 733.99507 -0.97718 0 0 0 0 0 0 0 0 + 27 29 325 325 2671 3040;3041 24952 15439 Mix4_TiO2_1_5 5087 24946 15433 Mix4_TiO2_1_4 5387 CON__P12763 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor P12763 0.982884 17.6059 0.982884 17.6059 5.27438E-39 207.78 0.233994 -2.43492 0.776796 29.399 0.878838 8.68263 3.63241E-32 177.73 0.850224 7.71402 0.00011022 95.039 0 0 0 0 1 S ASVESSSGEAFHV 5.27438E-39 207.78 _HTFSGVASVESSpSGEAFHVGK_ HTFSGVASVESS(0.017)S(0.983)GEAFHVGK HT(-121.19)FS(-109.78)GVAS(-97.41)VES(-42.22)S(-17.61)S(17.61)GEAFHVGK 13 3 733.99507 0.68018 2645600 107480 0 0 2501400 36807 0 0 + 28 31 77 77 2906 3310 27808 17323 Mix4_TiO2_1_4 4717 27808 17323 Mix4_TiO2_1_4 4717 CON__P13647;P13647 CON__P13647 CON__P13647 58 kDa cytokeratin;Cytokeratin-5;Keratin, type II cytoskeletal 5;Keratin-5;Type-II keratin Kb5 KRT5 >P13647 SWISS-PROT:P13647 Tax_Id=9606 Gene_Symbol=KRT5 Keratin, type II cytoskeletal 5;>sp|P13647|K2C5_HUMAN Keratin, type II cytoskeletal 5 OS=Homo sapiens GN=KRT5 PE=1 SV=3 P13647 0.944151 14.5059 0.944151 14.5059 0.084444 46.082 0 0 0 0 0 0 1 S SKRISISTSGGSF 0.084444 46.082 _ISIpSTSGGSFR_ IS(0.015)IS(0.944)T(0.033)S(0.008)GGSFR IS(-18.1)IS(14.51)T(-14.51)S(-20.86)GGS(-46.08)FR 4 2 596.27391 0.90304 28789 28789 0 0 0 0 0 0 + 29 32 62 62 Phosphoserine 5483 6239 53448 32645 Mix4_TiO2_Reinj_1_4 4933 53448 32645 Mix4_TiO2_Reinj_1_4 4933 CON__P35908;P35908 CON__P35908 CON__P35908 Cytokeratin-2e;Epithelial keratin-2e;Keratin, type II cytoskeletal 2 epidermal;Keratin-2 epidermis;Keratin-2e;Type-II keratin Kb2 KRT2;KRT2A;KRT2E >P35908 SWISS-PROT:P35908 Tax_Id=9606 Gene_Symbol=KRT2 Keratin, type II cytoskeletal 2 epidermal;>sp|P35908|K22E_HUMAN Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens GN=KRT2 PE=1 SV=2 P35908 0.999953 43.2385 0.7706 5.26236 0.828899 5.2624 0.999953 43.2385 0.062048 43.239 0 0 1 S GGFGSRSLVGLGG 0.062048 43.239 _pSLVGLGGTK_ S(1)LVGLGGTK S(43.24)LVGLGGT(-43.24)K 1 2 456.23353 -0.47072 93259 21874 0 0 71384 0 0 0 + 30 39;293 333;344 344 Phosphoserine 5421 6170 52852 32303 Mix4_TiO2_Reinj_1_4 8951 52849 32300 Mix4_TiO2_1_4 8417 CON__Q5XQN5;CON__Q922U2;CON__Q8BGZ7;CON__P50446;P04264;CON__P04264 CON__Q5XQN5;P04264 P04264 Cytokeratin-5;Keratin, type II cytoskeletal 5;Keratin-5;Type-II keratin Kb5;Cytokeratin-75;Keratin, type II cytoskeletal 75;Keratin-6 hair follicle;Keratin-75;Type II keratin-K6hf;Type-II keratin Kb18;Cytokeratin KRT2-6HF;Cytokeratin-6A;Keratin, type II cytoskeletal 6A;Keratin-6A;Keratin-6-alpha;67 kDa cytokeratin;Cytokeratin-1;Hair alpha protein;Keratin, type II cytoskeletal 1;Keratin-1;Type-II keratin Kb1 Krt2-5;Krt5;Kb18;Krt75;Krt2-6hf;Krtcap1;Ker2;Krt2-6;Krt2-6a;Krt6;Krt6a;KRT1;KRTA >Q5XQN5 SWISS-PROT:Q5XQN5 (Bos taurus) Keratin, type II cytoskeletal 5;>Q922U2 SWISS-PROT:Q922U2 Tax_Id=10090 Gene_Symbol=Krt5 Keratin, type II cytoskeletal 5;>Q8BGZ7 TREMBL:Q8BGZ7;Q99MH7 Tax_Id=10090 Gene_Symbol=Krt75 10 days neonate skin cDNA, RIKEN full Q5XQN5;Q922U2;Q8BGZ7;Q99MH7;P50446;P04264 1 82.1696 1 90.7338 2.20386E-08 157.55 1 82.1696 3.65398E-05 133.52 1 S SMDNNRSLDLDSI 2.20386E-08 157.55 _pSLDLDSIIAEVK_ S(1)LDLDSIIAEVK S(82.17)LDLDS(-82.17)IIAEVK 1 2 691.84437 0.40157 377600 0.50102 60874 0 0 316720 0 0 0 + 31 42 542 542 2593 2948 24242 15042 Mix4_TiO2_Reinj_1_6 1099 24242 15042 Mix4_TiO2_Reinj_1_6 1099 CON__Q86YZ3;Q86YZ3 CON__Q86YZ3 CON__Q86YZ3 Hornerin HRNR;S100A18 >Q86YZ3 SWISS-PROT:Q86YZ3 Tax_Id=9606 Gene_Symbol=HRNR Hornerin;>sp|Q86YZ3|HORN_HUMAN Hornerin OS=Homo sapiens GN=HRNR PE=1 SV=2 Q86YZ3 0.9772 17.0247 0 0 0.9772 17.0247 0.110084 39.82 1 S GSGQSPSPSRGRH CDK1;CDK2;Proline-directed 0.0057 0.110084 39.82 _HGSGSGQSPpSPSR_ HGSGSGQS(0.003)PS(0.977)PS(0.019)R HGS(-39.82)GS(-39.82)GQS(-24.84)PS(17.02)PS(-17.02)R 10 2 660.77005 -0.54086 83129 0 0 0 83129 0 0 0 + 32 46 10 10 475 539 4460 2682 Mix4_TiO2_1_5 2641 4460 2682 Mix4_TiO2_1_5 2641 O00159-3 O00159-3 O00159-3 >sp|O00159-3|MYO1C_HUMAN Isoform NM1 of Myosin-Ic OS=Homo sapiens GN=MYO1C 0.999981 47.2931 0.999981 47.2931 0.046097 47.293 0 0 1 S RASALGSDGVRVT CK1 0.143 0.046097 47.293 _ASALGpSDGVR_ ASALGS(1)DGVR AS(-47.29)ALGS(47.29)DGVR 6 2 506.7266 0.32056 8427.8 8427.8 0 0 0 0 0 0 33 46 389 389 1305 1472 12187 7465 Mix4_TiO2_1_5 3718 12187 7465 Mix4_TiO2_1_5 3718 O00159-3;O00159;O00159-2 O00159-3 O00159-3 >sp|O00159-3|MYO1C_HUMAN Isoform NM1 of Myosin-Ic OS=Homo sapiens GN=MYO1C;>sp|O00159|MYO1C_HUMAN Myosin-Ic OS=Homo sapiens GN=MYO1C PE=1 SV=3;>sp|O00159-2|MYO1C_HUMAN Isoform 2 of Myosin-Ic OS=Homo sapiens GN=MYO1C 0.999687 35.0496 0.999687 35.0496 9.06305E-05 127.67 0 0 0.994418 22.508 0.00199962 102.8 0 0 0 0 1 S ASKDVESPSWRST ERK/MAPK;Proline-directed 0.0034 9.06305E-05 127.67 _DVEpSPSWR_ DVES(1)PSWR DVES(35.05)PS(-35.05)WR 4 2 528.21332 0.20221 1470400 320030 0 0 1150400 0 0 0 34 46 717 717 5013 5701 48438 29638 Mix4_TiO2_Reinj_1_5 1661 48438 29638 Mix4_TiO2_Reinj_1_5 1661 O00159-3;O00159;O00159-2 O00159-3 O00159-3 >sp|O00159-3|MYO1C_HUMAN Isoform NM1 of Myosin-Ic OS=Homo sapiens GN=MYO1C;>sp|O00159|MYO1C_HUMAN Myosin-Ic OS=Homo sapiens GN=MYO1C PE=1 SV=3;>sp|O00159-2|MYO1C_HUMAN Isoform 2 of Myosin-Ic OS=Homo sapiens GN=MYO1C 0.99998 47.0267 0.993147 21.611 0.351392 21.611 0.99998 47.0267 0.120957 51.149 0.993147 21.611 0.351392 21.611 0.988508 19.346 0.439055 19.346 1 S LEVRRQSLATKIQ AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.004788 0.120957 51.149 _RQpSLATK_ RQS(1)LATK RQS(47.03)LAT(-47.03)K 3 2 442.22349 0.062433 734480 25866 0 0 525580 0 83520 99513 35 46 845 845 5378 6121 52279 31976 Mix4_TiO2_Reinj_1_5 5065 52274 31967 Mix4_InSol_TiO2_1 5294 O00159-3;O00159;O00159-2 O00159-3 O00159-3 >sp|O00159-3|MYO1C_HUMAN Isoform NM1 of Myosin-Ic OS=Homo sapiens GN=MYO1C;>sp|O00159|MYO1C_HUMAN Myosin-Ic OS=Homo sapiens GN=MYO1C PE=1 SV=3;>sp|O00159-2|MYO1C_HUMAN Isoform 2 of Myosin-Ic OS=Homo sapiens GN=MYO1C 0.999873 38.9567 0.994735 22.7627 0.295883 27.709 0.999873 38.9567 0.187303 40.018 0.999706 35.3144 0.124131 50.593 0.993976 22.1746 0.209936 37.452 1 S KYCRSISPEWKQQ CAMK2;Proline-directed 0.042 0.124131 50.593 _SIpSPEWK_ SIS(1)PEWK S(-38.96)IS(38.96)PEWK 3 2 463.7046 -0.093711 819260 144970 0 0 505120 0 87979 81195 36 48 15 15 5121 5825 49550 30274 Mix4_InSol_TiO2_1 7033 49553 30277 Mix4_TiO2_Reinj_1_2 5680 O00193 O00193 O00193 >sp|O00193|SMAP_HUMAN Small acidic protein OS=Homo sapiens GN=SMAP PE=1 SV=1 0.5 0 0.499914 0 8.51049E-05 96.304 0.0776576 -10.7471 1.41837E-33 190.34 0.5 0 4.88587E-25 171.83 0 0 1 S PHGVKRSASPDDD 1.41837E-33 190.34 _pSASPDDDLGSSNWEAADLGNEER_ S(0.5)AS(0.5)PDDDLGSSNWEAADLGNEER S(0)AS(0)PDDDLGS(-57.49)S(-69.52)NWEAADLGNEER 1 3 839.00128 0.02261 145690 1.6482 34871 0 0 0 0 110820 0 37 48 17 17 5121 5825 49553 30277 Mix4_TiO2_Reinj_1_2 5680 49553 30277 Mix4_TiO2_Reinj_1_2 5680 O00193 O00193 O00193 >sp|O00193|SMAP_HUMAN Small acidic protein OS=Homo sapiens GN=SMAP PE=1 SV=1 0.922342 10.7471 0.55543 0.966885 8.51049E-05 96.304 0.922342 10.7471 1.41837E-33 190.34 0.5 0 4.88587E-25 171.83 0 0 1 S GVKRSASPDDDLG CAMK2;CHK1;CK2;PKA;PKD;Proline-directed 0.003024 1.41837E-33 190.34 _SApSPDDDLGSSNWEAADLGNEER_ S(0.078)AS(0.922)PDDDLGSSNWEAADLGNEER S(-10.75)AS(10.75)PDDDLGS(-114.09)S(-133.07)NWEAADLGNEER 3 2 1257.9983 0.46644 554090 6.2684 163450 0 0 279820 0 110820 0 38 49 276 276 4037 4599 38170 23433 Mix4_TiO2_Reinj_1_5 3565 38170 23433 Mix4_TiO2_Reinj_1_5 3565 O00203 O00203 O00203 >sp|O00203|AP3B1_HUMAN AP-3 complex subunit beta-1 OS=Homo sapiens GN=AP3B1 PE=1 SV=3 0.999975 46.0596 0 0 0.999975 46.0596 0.000111541 120.68 1 S GKNFYESDDDQKE CK2 0.117 0.000111541 120.68 _NFYEpSDDDQKEK_ NFYES(1)DDDQKEK NFY(-46.06)ES(46.06)DDDQKEK 5 2 799.30633 0.4536 332440 0 0 0 332440 0 0 0 39 51 181 181 1536;1537;1538;3548 1726;1727;1728;4002 14125 8614 Mix4_TiO2_Reinj_1_6 3537 14137 8626 Mix4_TiO2_Reinj_1_6 3399 O00264 O00264 O00264 >sp|O00264|PGRC1_HUMAN Membrane-associated progesterone receptor component 1 OS=Homo sapiens GN=PGRMC1 PE=1 SV=3 0.999174 31.7702 0.965618 14.6449 7.68404E-07 110.44 0.401964 0 0.852105 25.633 0.999174 31.7702 4.03593E-16 146.74 0 0 0.992938 21.5965 0.0643409 55.032 0.959242 15.8637 0.0137115 65.304 1 S EEPTVYSDEEEPK CK2 0.117 4.03593E-16 146.74 _EGEEPTVYpSDEEEPK_ EGEEPTVY(0.001)S(0.999)DEEEPK EGEEPT(-37.92)VY(-31.77)S(31.77)DEEEPK 9 2 909.35368 0.1532 8219800 1731300 0 0 5256900 0 126380 1105200 40 51 57 57 2140;2942 2425;3348 19677 12027 Mix4_TiO2_1_6 3404 19677 12027 Mix4_TiO2_1_6 3404 O00264 O00264 O00264 >sp|O00264|PGRC1_HUMAN Membrane-associated progesterone receptor component 1 OS=Homo sapiens GN=PGRMC1 PE=1 SV=3 0.999998 57.367 0.999998 57.367 2.66728E-39 216.93 0 0 0.999829 37.6737 6.04751E-32 195.9 0 0 0.984952 18.1594 0.0391736 58.594 1 S PAASGDSDDDEPP CK1;CK2 0.081 2.66728E-39 216.93 _GDQPAASGDpSDDDEPPPLPR_ GDQPAASGDS(1)DDDEPPPLPR GDQPAAS(-57.37)GDS(57.37)DDDEPPPLPR 10 2 1058.4288 -1.0327 1740700 2.4152 432940 0 0 1089200 0 0 218540 41 53 258 258 5917;5918 6749;6750 58325 35396 Mix4_TiO2_Reinj_1_4 3081 58325 35396 Mix4_TiO2_Reinj_1_4 3081 O00303 O00303 O00303 >sp|O00303|EIF3F_HUMAN Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens GN=EIF3F PE=1 SV=1 0.999999 61.0218 0.999982 47.4558 0.142004 47.456 0 0 0.999999 61.0218 0.0692077 61.022 0 0 0.498986 0 0.124053 53.852 1 S IMKTCFSPNRVIG CDK1;CDK2;Proline-directed 0.0057 0.0692077 61.022 _TCFpSPNR_ TCFS(1)PNR T(-61.02)CFS(61.02)PNR 4 2 481.18351 0.27345 271260 47125 0 0 224140 0 0 0 42 54 211 211 6261 7152 62350 37939 Mix4_TiO2_Reinj_1_5 2134 62350 37939 Mix4_TiO2_Reinj_1_5 2134 O00308 O00308 O00308 >sp|O00308|WWP2_HUMAN NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens GN=WWP2 PE=1 SV=2 1 81.9909 0.993667 26.7277 0.320115 26.728 1 81.9909 7.03467E-12 95.263 1 S PATGEQSPGARSR CK1;Proline-directed 0.05 7.03467E-12 95.263 _TTPATGEQpSPGAR_ TTPATGEQS(1)PGAR T(-95.26)T(-95.26)PAT(-81.99)GEQS(81.99)PGAR 9 2 676.79574 -0.30648 75452 75452 0 0 0 0 0 0 43 57 845 845 5006 5693 48386 29607 Mix4_TiO2_1_5 6300 48386 29607 Mix4_TiO2_1_5 6300 O00410-3;O00410;O00410-2 O00410-3 O00410-3 >sp|O00410-3|IPO5_HUMAN Isoform 3 of Importin-5 OS=Homo sapiens GN=IPO5;>sp|O00410|IPO5_HUMAN Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4;>sp|O00410-2|IPO5_HUMAN Isoform 2 of Importin-5 OS=Homo sapiens GN=IPO5 1 68.5056 1 68.5056 1.76854E-12 133.29 0.999997 55.4752 4.40683E-12 127.19 1 S DEQVEESLQDEDD CK2;PLK;PLK1 0.0027378 1.76854E-12 133.29 _RQDEDYDEQVEEpSLQDEDDNDVYILTK_ RQDEDYDEQVEES(1)LQDEDDNDVYILTK RQDEDY(-81.25)DEQVEES(68.51)LQDEDDNDVY(-68.51)ILT(-95.39)K 13 3 1128.4701 0.25803 3357900 0.031744 580570 0 0 2777400 0 0 0 44 60 421 421 5296 6029 51419 31491 Mix4_TiO2_1_4 8038 51421 31494 Mix4_TiO2_Reinj_1_4 8719 O00444;O00444-2;O00444-3 O00444 O00444 >sp|O00444|PLK4_HUMAN Serine/threonine-protein kinase PLK4 OS=Homo sapiens GN=PLK4 PE=1 SV=3;>sp|O00444-2|PLK4_HUMAN Isoform 2 of Serine/threonine-protein kinase PLK4 OS=Homo sapiens GN=PLK4;>sp|O00444-3|PLK4_HUMAN Isoform 3 of Serine/threonine-protein kin 0.766692 5.9491 0.766692 5.9491 1.12681E-11 128.87 0.235774 -4.84036 4.37977E-26 173.11 0 0 0 0 1 S ENEERYSPTDNNA CK2;PKA;Proline-directed 0.042 4.37977E-26 173.11 _SGGGENEERYpSPTDNNANIFNFFK_ SGGGENEERY(0.195)S(0.767)PT(0.038)DNNANIFNFFK S(-46.97)GGGENEERY(-5.95)S(5.95)PT(-13)DNNANIFNFFK 11 3 929.7276 -0.74882 435810 435810 0 0 0 0 0 0 45 63 60 60 4373 4972 41460 25479 Mix4_TiO2_1_4 5374 41460 25479 Mix4_TiO2_1_4 5374 O00505 O00505 O00505 >sp|O00505|IMA3_HUMAN Importin subunit alpha-3 OS=Homo sapiens GN=KPNA3 PE=1 SV=2 0.999985 48.1358 0.999985 48.1358 4.66357E-06 105.03 0 0 1 S EESLEDSDVDADF CK1;CK2;NEK6 0.076 4.66357E-06 105.03 _NVPQEESLEDpSDVDADFK_ NVPQEESLEDS(1)DVDADFK NVPQEES(-48.14)LEDS(48.14)DVDADFK 11 2 1058.9334 1.1814 176020 9.5859 176020 0 0 0 0 0 0 46 66 36 36 3122 3546 29722 18513 Mix4_TiO2_1_2 5090 29722 18513 Mix4_TiO2_1_2 5090 O00559 O00559 O00559 >sp|O00559|RCAS1_HUMAN Receptor-binding cancer antigen expressed on SiSo cells OS=Homo sapiens GN=EBAG9 PE=1 SV=1 0.999491 32.9377 0.999491 32.9377 0.0100838 68.881 0.715113 3.99709 0.0109747 67.869 0 0 0 0 1 S GRGRKLSGDQITL CAMK2;PKA;PKA/AKT 0.001764 0.0100838 68.881 _KLpSGDQITLPTTVDYSSVPK_ KLS(0.999)GDQIT(0.001)LPTTVDYSSVPK KLS(32.94)GDQIT(-32.94)LPT(-68.88)T(-68.88)VDY(-68.88)S(-68.88)S(-68.88)VPK 3 3 743.70652 0.0099855 148270 36028 0 0 112240 0 0 0 47 67 6 6 5487 6244 53568 32757 Mix4_TiO2_Reinj_1_2 6491 53568 32757 Mix4_TiO2_Reinj_1_2 6491 O00560;O00560-2 O00560 O00560 >sp|O00560|SDCB1_HUMAN Syntenin-1 OS=Homo sapiens GN=SDCBP PE=1 SV=1;>sp|O00560-2|SDCB1_HUMAN Isoform 2 of Syntenin-1 OS=Homo sapiens GN=SDCBP 0.99999 52.8208 0 0 0.99999 52.8208 0.0483383 52.821 1 S _MSLYPSLEDLKV CK1;CK2;NEK6 0.076 0.0483383 52.821 _(ac)SLYPpSLEDLKVDK_ SLYPS(1)LEDLKVDK S(-52.82)LY(-52.82)PS(52.82)LEDLKVDK 5 2 814.89459 0.30078 28953 0 0 0 28953 0 0 0 48 68 570 570 1501 1685 13908 8465 Mix4_TiO2_Reinj_1_3 3892 13908 8465 Mix4_TiO2_Reinj_1_3 3892 O00567 O00567 O00567 >sp|O00567|NOP56_HUMAN Nucleolar protein 56 OS=Homo sapiens GN=NOP56 PE=1 SV=4 0.999041 30.1793 0.899837 9.53457 6.77987E-05 112.4 0.999041 30.1793 5.52272E-10 155.81 1 S KEEPVSSGPEEAV CK2 0.117 5.52272E-10 155.81 _EEPVSpSGPEEAVGK_ EEPVS(0.001)S(0.999)GPEEAVGK EEPVS(-30.18)S(30.18)GPEEAVGK 6 2 747.82162 -0.46627 489970 190480 0 0 299490 0 0 0 49 72 696 696 2366 2678 21899 13618 Mix4_TiO2_Reinj_1_1 3777 21899 13618 Mix4_TiO2_Reinj_1_1 3777 O14497;O14497-2;O14497-3 O14497 O14497 >sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A PE=1 SV=3;>sp|O14497-2|ARI1A_HUMAN Isoform 2 of AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A;>sp|O14497-3|ARI1A_HUMAN Isoform 3 0.999838 37.9102 0.987104 18.8392 1.71226E-16 169.45 0 0 0.999838 37.9102 1.88283E-20 186.58 0 0 0.996072 24.0815 0.100382 49.201 0.9986 28.5652 0.0633812 54.583 1 S PGIRGPSPSPVGS CAMK2;Proline-directed 0.042 1.88283E-20 186.58 _GPpSPSPVGSPASVAQSR_ GPS(1)PSPVGSPASVAQSR GPS(37.91)PS(-37.91)PVGS(-98.39)PAS(-144.95)VAQS(-186.58)R 3 2 830.88816 -0.18126 1387200 325310 0 0 1015000 0 23409 23532 50 72 357 357 5345 6086 51905 31765 Mix4_InSol_TiO2_1 4099 51907 31767 Mix4_TiO2_Reinj_1_1 3200 O14497;O14497-2 O14497 O14497 >sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A PE=1 SV=3;>sp|O14497-2|ARI1A_HUMAN Isoform 2 of AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A 0.499355 0 0.00135311 -28.6762 0.125198 48.216 0.499355 0 0.182092 41.845 0.162174 -6.92907 0.867231 25.283 1 S GGAQQRSHHAPMS 0.125198 48.216 _pSHHAPMSPGSSGGGGQPLAR_ S(0.499)HHAPMS(0.499)PGS(0.001)SGGGGQPLAR S(0)HHAPMS(0)PGS(-26.04)S(-40.17)GGGGQPLAR 1 3 656.62291 -0.90529 0 0 0 0 0 0 0 0 51 72 363 363 5345 6086 51907 31767 Mix4_TiO2_Reinj_1_1 3200 51907 31767 Mix4_TiO2_Reinj_1_1 3200 O14497;O14497-2 O14497 O14497 >sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A PE=1 SV=3;>sp|O14497-2|ARI1A_HUMAN Isoform 2 of AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A 0.997583 28.6762 0.997583 28.6762 0.125198 48.216 0.499355 0 0.182092 41.845 0.799627 6.92907 0.867231 25.283 1 S SHHAPMSPGSSGG ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.125198 48.216 _SHHAPMpSPGSSGGGGQPLAR_ S(0.001)HHAPMS(0.998)PGS(0.001)SGGGGQPLAR S(-28.68)HHAPMS(28.68)PGS(-30.57)S(-37.21)GGGGQPLAR 7 3 656.62291 0.0082818 204680 0 0 0 112080 0 0 92603 52 72 1754 1754 6616 7574;7575 67124 41186 Mix4_TiO2_Reinj_1_1 6036 67120 41185 Mix4_TiO2_Reinj_1_1 5391 O14497;O14497-2;O14497-3 O14497 O14497 >sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A PE=1 SV=3;>sp|O14497-2|ARI1A_HUMAN Isoform 2 of AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A;>sp|O14497-3|ARI1A_HUMAN Isoform 3 0.5 0 0.5 0 0.0161308 62.034 0 0 0.5 0 1.90803E-06 99.051 1 S GRFSKVSSPAPME CK1 0.081 1.90803E-06 99.051 _VpSSPAPMEGGEEEEELLGPK_ VS(0.5)S(0.5)PAPMEGGEEEEELLGPK VS(0)S(0)PAPMEGGEEEEELLGPK 2 2 1082.9714 0.38592 355230 81546 0 0 273680 0 0 0 53 72 1755 1755 6616 7574;7575 67119 41184 Mix4_TiO2_Reinj_1_1 5381 67120 41185 Mix4_TiO2_Reinj_1_1 5391 O14497;O14497-2;O14497-3 O14497 O14497 >sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A PE=1 SV=3;>sp|O14497-2|ARI1A_HUMAN Isoform 2 of AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A;>sp|O14497-3|ARI1A_HUMAN Isoform 3 0.821413 6.62712 0.5 0 0.0161308 62.034 0 0 0.821413 6.62712 1.90803E-06 99.051 1 S RFSKVSSPAPMEG CK1;ERK/MAPK;Polo box;Proline-directed 0.0034 1.90803E-06 99.051 _VSpSPAPM(ox)EGGEEEEELLGPK_ VS(0.179)S(0.821)PAPMEGGEEEEELLGPK VS(-6.63)S(6.63)PAPMEGGEEEEELLGPK 3 2 1090.9689 0.10357 576930 81546 0 0 495390 0 0 0 54 73 326 326 342 389 3155 1912 Mix4_TiO2_1_5 4204 3154 1910 Mix4_TiO2_1_3 4146 O14545 O14545 O14545 >sp|O14545|TRAD1_HUMAN TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens GN=TRAFD1 PE=1 SV=1 0.238833 0.733143 0.238833 0.733143 0.0404537 54.939 0 0 0.0993848 -7.48527 0.816278 7.4853 0 0 0.232418 -2.90921 0.728179 10.496 1 S SLNTGSSSPRGVE 0.0404537 54.939 _ALPSLNTGSpSSPR_ ALPS(0.186)LNT(0.186)GS(0.186)S(0.239)S(0.202)PR ALPS(-1.07)LNT(-1.07)GS(-1.07)S(0.73)S(-0.73)PR 10 2 683.82176 -0.22586 0 0 0 0 0 0 0 0 55 73 327 327 342 389 3154 1910 Mix4_TiO2_1_3 4146 3154 1910 Mix4_TiO2_1_3 4146 O14545 O14545 O14545 >sp|O14545|TRAD1_HUMAN TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens GN=TRAFD1 PE=1 SV=1 0.972131 16.6026 0.972131 16.6026 0.0404537 54.939 0 0 0.55699 5.84911 0.816278 7.4853 0 0 0.454142 2.90921 0.728179 10.496 1 S LNTGSSSPRGVEE CDK1;CK1;Polo box;Proline-directed 0.00405 0.0404537 54.939 _ALPSLNTGSSpSPR_ ALPSLNT(0.004)GS(0.003)S(0.021)S(0.972)PR ALPS(-54.94)LNT(-24.08)GS(-25.38)S(-16.6)S(16.6)PR 11 2 683.82176 -0.013696 836830 190990 0 0 645840 0 0 0 56 73 415 415 3355 3795 31610 19551 Mix4_InSol_TiO2_1 4812 31610 19551 Mix4_InSol_TiO2_1 4812 O14545 O14545 O14545 >sp|O14545|TRAD1_HUMAN TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens GN=TRAFD1 PE=1 SV=1 0.983721 17.8125 0.94384 12.2547 1.16623E-08 137.84 0 0 0.973503 15.6514 8.52538E-09 142.91 0.983721 17.8125 1.34582E-15 178.94 0.974988 15.9085 3.39144E-07 133.93 1 S SQPQETSPELPRR Proline-directed 0.05 1.34582E-15 178.94 _LDSQPQETpSPELPR_ LDSQPQET(0.016)S(0.984)PELPR LDS(-143.51)QPQET(-17.81)S(17.81)PELPR 9 2 838.88 -0.13001 1177800 193120 0 0 596710 0 204060 183920 57 74 1971 1971 958 1080 9136 5598 Mix4_TiO2_Reinj_1_5 2536 9134 5596 Mix4_InSol_TiO2_1 2785 O14578;O14578-3 O14578 O14578 >sp|O14578|CTRO_HUMAN Citron Rho-interacting kinase OS=Homo sapiens GN=CIT PE=1 SV=2;>sp|O14578-3|CTRO_HUMAN Isoform 3 of Citron Rho-interacting kinase OS=Homo sapiens GN=CIT 1 30.355 0 0 1 30.355 0.193134 30.355 1 46.9062 0.0472665 46.906 1 36.4637 0.119413 36.464 1 S ELRRDKSPGRPLE CAMK2;CDK1;CDK2;CHK1;CHK1/2;PKD;Proline-directed 0.003192 0.0472665 46.906 _DKpSPGRPLER_ DKS(1)PGRPLER DKS(30.36)PGRPLER 3 2 617.80063 0.2781 210170 0 0 0 71631 0 76548 61987 58 75 10 10 401 459 3809 2263 Mix4_TiO2_1_2 5683 3810 2265 Mix4_TiO2_Reinj_1_2 6740 O14579 O14579 O14579 >sp|O14579|COPE_HUMAN Coatomer subunit epsilon OS=Homo sapiens GN=COPE PE=1 SV=3 0.5 0 0.5 0 1.07791E-18 156.49 0.0155909 -18.003 7.87878E-24 158.09 0 0 0 0 1 S PAPGPASGGSGEV 7.87878E-24 158.09 _APPAPGPApSGGSGEVDELFDVK_ APPAPGPAS(0.5)GGS(0.5)GEVDELFDVK APPAPGPAS(0)GGS(0)GEVDELFDVK 9 3 726.33146 -0.28477 80607 0.34148 80607 0 0 0 0 0 0 59 75 13 13 401 459 3810 2265 Mix4_TiO2_Reinj_1_2 6740 3810 2265 Mix4_TiO2_Reinj_1_2 6740 O14579 O14579 O14579 >sp|O14579|COPE_HUMAN Coatomer subunit epsilon OS=Homo sapiens GN=COPE PE=1 SV=3 0.996207 24.194 0.978753 16.6338 1.07791E-18 156.49 0.996207 24.194 7.87878E-24 158.09 0 0 0 0 1 S GPASGGSGEVDEL CK1 0.081 7.87878E-24 158.09 _APPAPGPASGGpSGEVDELFDVK_ APPAPGPAS(0.004)GGS(0.996)GEVDELFDVK APPAPGPAS(-24.19)GGS(24.19)GEVDELFDVK 12 2 1088.9935 -0.40423 696250 2.9496 227070 0 0 469190 0 0 0 60 75 45 45 3738;3739 4217;4218 35323 21854 Mix4_TiO2_Reinj_1_5 1771 35327 21856 Mix4_TiO2_Reinj_1_2 2838 O14579 O14579 O14579 >sp|O14579|COPE_HUMAN Coatomer subunit epsilon OS=Homo sapiens GN=COPE PE=1 SV=3 0.998908 29.6121 0.997859 26.6847 0.591927 26.685 0 0 0.998908 29.6121 0.0194303 56.123 0 0 0 0 1 S QRVKLSSPERDVE CDK1;CDK2;Polo box;Proline-directed 0.00405 0.0194303 56.123 _LSpSPER_ LS(0.001)S(0.999)PER LS(-29.61)S(29.61)PER 3 2 384.66802 0.28791 512750 49598 0 0 463150 0 0 0 61 75 99 99 4840 5500 46271 28293 Mix4_TiO2_Reinj_1_6 4738 46269 28291 Mix4_TiO2_Reinj_1_2 4832 O14579 O14579 O14579 >sp|O14579|COPE_HUMAN Coatomer subunit epsilon OS=Homo sapiens GN=COPE PE=1 SV=3 1 41.8184 1 10.1596 0.0013599 90.921 1 41.8184 0.00234439 101.96 1 S HESRRDSIVAELD AURORA;AURORA-1;AURORA-A;CAMK2;CK1;PKA 0.004788 0.00234439 101.96 _RDpSIVAELDR_ RDS(1)IVAELDR RDS(41.82)IVAELDR 3 2 627.29792 -0.21884 3338800 681960 0 0 2656800 0 0 0 62 79 56 56 452;4803 514;5453 45775 27998 Mix4_TiO2_Reinj_1_6 1606 45768 27988 Mix4_InSol_Tio2_Reinj_1 2084 O14681 O14681 O14681 >sp|O14681|EI24_HUMAN Etoposide-induced protein 2.4 homolog OS=Homo sapiens GN=EI24 PE=1 SV=4 1 36.3102 1 14.6184 0.62202 14.618 0 0 1 36.3102 0.107442 53.521 0 0 1 44.0176 0.161597 44.018 1 69.7226 0.06949 69.723 1 S AQRRAQSIERKQE CAMK2 0.042 0.06949 69.723 _RAQpSIER_ RAQS(1)IER RAQS(36.31)IER 4 2 470.22402 -0.071991 4092500 55761 0 0 2753400 0 603090 680240 63 79 326 326 2036 2308;2309 18612 11341 Mix4_TiO2_Reinj_1_1 3058 18608 11332 Mix4_TiO2_1_1 2629 O14681 O14681 O14681 >sp|O14681|EI24_HUMAN Etoposide-induced protein 2.4 homolog OS=Homo sapiens GN=EI24 PE=1 SV=4 0.998435 28.0476 1 40.3053 0.0361935 50.573 0.997669 26.315 0.140781 34.693 0.998435 28.0476 0.00257339 73.919 0 0 0.995031 23.0158 0.281703 23.016 0 0 1 S SAEKFPSPHPSPA GSK3;Proline-directed 0.05 0.00245931 74.271 _FPpSPHPSPAK_ FPS(0.998)PHPS(0.002)PAK FPS(28.05)PHPS(-28.05)PAK 3 2 572.76298 0.49371 649220 45722 13556 0 563520 0 26415 0 64 79 330 330 2036 2308;2309 18615 11347 Mix4_TiO2_Reinj_1_4 3532 18608 11332 Mix4_TiO2_1_1 2629 O14681 O14681 O14681 >sp|O14681|EI24_HUMAN Etoposide-induced protein 2.4 homolog OS=Homo sapiens GN=EI24 PE=1 SV=4 0.999934 41.7879 0.949453 12.7378 0.00245931 74.271 0.00233068 -26.315 0.140781 34.693 0.999934 41.7879 0.00257339 73.919 0 0 0.00496886 -23.0158 0.281703 23.016 0 0 1 S FPSPHPSPAKLKA CDK1;CDK2;CK1;Proline-directed 0.0057 0.00245931 74.271 _FPSPHPpSPAK_ FPSPHPS(1)PAK FPS(-41.79)PHPS(41.79)PAK 7 2 572.76298 0.86051 862330 157970 0 0 704350 0 0 0 65 80 14 14 3062 3482 29174 18230 Mix4_InSol_TiO2_1 3091 29179 18235 Mix4_TiO2_Reinj_1_5 2750 O14683 O14683 O14683 >sp|O14683|P5I11_HUMAN Tumor protein p53-inducible protein 11 OS=Homo sapiens GN=TP53I11 PE=2 SV=2 0.975994 16.1728 0.884337 8.83428 0.00126096 89.046 0.975994 16.1728 0.156452 33.395 0.632544 5.36915 0.675379 5.3692 1 S PLMKKHSQTDLVS CHK1;CK2;PKD 0.020748 0.00126096 89.046 _KHpSQTDLVSR_ KHS(0.976)QT(0.024)DLVSR KHS(16.17)QT(-16.17)DLVS(-33.39)R 3 2 625.79808 0.2824 501960 0 0 0 334400 0 135180 32379 66 81 21 21 6816 7800 69107 42370 Mix4_TiO2_1_1 5670 69107 42370 Mix4_TiO2_1_1 5670 O14715;Q99666;Q99666-2 O14715 O14715 >sp|O14715|RGPD8_HUMAN RANBP2-like and GRIP domain-containing protein 8 OS=Homo sapiens GN=RGPD8 PE=1 SV=2;>sp|Q99666|RGPD5_HUMAN RANBP2-like and GRIP domain-containing protein 5/6 OS=Homo sapiens GN=RGPD5 PE=1 SV=3;>sp|Q99666-2|RGPD5_HUMAN Isoform 2 of RA 0.999843 42.8171 0.999843 42.8171 0.0850654 42.817 0 0 0 0 0 0 1 S VLGLTPSPRQKSM CDK1;NEK6;Proline-directed 0.0057 0.0850654 42.817 _YVASVLGLTPpSPR_ YVASVLGLTPS(1)PR Y(-42.82)VAS(-42.82)VLGLT(-42.82)PS(42.82)PR 11 2 720.36834 0.45258 11791 11791 0 0 0 0 0 0 67 83 296 296 2604 2962;2964 24335 15123 Mix4_TiO2_Reinj_1_4 6032 24329 15115 Mix4_TiO2_1_4 5171 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 1 80.4201 0.99755 26.0975 7.65664E-25 174.98 0 0 1 80.4201 1.19797E-23 160.59 1 72.955 2.08505E-11 132.28 0.999991 50.2701 4.31047E-07 109.59 1 S FSKHIQSNLDFSP CK2 0.117 7.65664E-25 174.98 _HIQpSNLDFSPVNSASSEENVK_ HIQS(1)NLDFSPVNSASSEENVK HIQS(80.42)NLDFS(-80.42)PVNS(-105.14)AS(-126.46)S(-137.62)EENVK 4 2 1191.5341 -0.28066 6435500 4.1207 564500 0 0 5374500 0 342620 153860 68 83 301 301 2604 2962;2964 24330 15117 Mix4_TiO2_1_4 5224 24329 15115 Mix4_TiO2_1_4 5171 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.940424 14.6036 0.940424 14.6036 7.65664E-25 174.98 0 0 0.0842793 -7.9517 1.19797E-23 160.59 0.00194039 -27.1127 2.08505E-11 132.28 9.39697E-06 -50.2701 4.31047E-07 109.59 1 S QSNLDFSPVNSAS GSK3;NEK6;Proline-directed 0.05 7.65664E-25 174.98 _HIQSNLDFpSPVNSASSEENVK_ HIQSNLDFS(0.94)PVNS(0.033)AS(0.026)S(0.001)EENVK HIQS(-40.51)NLDFS(14.6)PVNS(-14.6)AS(-15.55)S(-31.32)EENVK 9 3 794.69183 -1.156 596340 0.38185 596340 0 0 0 0 0 0 69 83 305 305 2604 2962;2964 24329 15115 Mix4_TiO2_1_4 5171 24329 15115 Mix4_TiO2_1_4 5171 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.963988 16.616 0.963988 16.616 7.65664E-25 174.98 0 0 0.525885 1.385 1.19797E-23 160.59 2.21249E-08 -76.5428 2.08505E-11 132.28 7.57001E-09 -81.209 4.31047E-07 109.59 1 S DFSPVNSASSEEN CK1 0.143 7.65664E-25 174.98 _HIQSNLDFSPVNpSASSEENVK_ HIQSNLDFSPVNS(0.964)AS(0.015)S(0.021)EENVK HIQS(-163.33)NLDFS(-57.49)PVNS(16.62)AS(-18.08)S(-16.62)EENVK 13 2 1191.5341 -0.45228 1567700 1.0038 403350 0 0 1164400 0 0 0 70 83 307 307 2604 2962;2964 24332 15119 Mix4_TiO2_Reinj_1_4 5775 24329 15115 Mix4_TiO2_1_4 5171 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.805198 6.54905 0.0405275 -13.508 0.000527343 80.583 0 0 0.805198 6.54905 1.19797E-23 160.59 2.21249E-08 -76.5428 2.08505E-11 132.28 2.09142E-10 -96.7955 4.31047E-07 109.59 1 S SPVNSASSEENVK CK2 0.117 7.65664E-25 174.98 _HIQSNLDFSPVNSApSSEENVK_ HIQSNLDFSPVNS(0.178)AS(0.805)S(0.017)EENVK HIQS(-100.31)NLDFS(-67.39)PVNS(-6.55)AS(6.55)S(-16.87)EENVK 15 3 794.69183 -0.64477 3305100 2.1163 0 0 0 3305100 0 0 0 71 83 308 308 2604 2962;2964 24369 15128 Mix4_TiO2_1_4 5555 24369 15128 Mix4_TiO2_1_4 5555 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.908964 12.5641 0.908964 12.5641 0.000527343 80.583 0 0 0.0165645 -16.8673 1.19797E-23 160.59 2.21249E-08 -76.5428 2.08505E-11 132.28 1.09788E-11 -109.594 4.31047E-07 109.59 2 S PVNSASSEENVKY CK1 0.081 0.000527343 80.583 _HIQpSNLDFSPVNSASpSEENVK_ HIQS(1)NLDFSPVNS(0.05)AS(0.041)S(0.909)EENVK HIQS(50.01)NLDFS(-38.03)PVNS(-12.56)AS(-13.51)S(12.56)EENVK 16 2 1231.5173 0.46945 76436 0.048943 76436 0 0 0 0 0 0 72 83 333 333 6000 6840 59240 35993 Mix4_TiO2_Reinj_1_4 7955 59239 35992 Mix4_TiO2_1_4 7233 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.506394 0.391723 0.106666 -7.08548 1.08399E-09 152.06 0 0 0.506394 0.391723 1.22952E-07 134.12 0 0 0 0 1 S LWDTSPSYIDKLV CK2 0.117 1.08399E-09 152.06 _TGLSLWDTSPpSYIDK_ TGLSLWDT(0.463)S(0.031)PS(0.506)YIDK T(-106.89)GLS(-98.42)LWDT(-0.39)S(-12.15)PS(0.39)Y(-46.91)IDK 11 2 881.9004 0.063734 763930 0 0 0 763930 0 0 0 73 83 280 280 6642 7604;7605 67404 41413 Mix4_TiO2_1_4 3415 67404 41413 Mix4_TiO2_1_4 3415 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.981123 17.3988 0.981123 17.3988 0.121427 42.866 4.01314E-06 -50.9471 0.00239705 83.188 0.185121 -2.79641 0.00107337 92.162 0.000980131 -30.0726 3.69748E-07 127.34 0.282813 -1.53357 0.00937782 73.874 2 S KRPRVTSGGVSES CAMK2;GSK3;PKA/AKT 0.001764 0.121427 42.866 _VTpSGGVSEpSPSGFSK_ VT(0.019)S(0.981)GGVS(0.205)ES(0.792)PS(0.003)GFSK VT(-17.4)S(17.4)GGVS(-5.88)ES(5.88)PS(-24.8)GFS(-42.87)K 3 2 793.31278 0.34809 26028 26028 0 0 0 0 0 0 74 83 284 284 6642 7604;7605 67388 41397 Mix4_InSol_TiO2_1 4324 67388 41397 Mix4_InSol_TiO2_1 4324 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.996653 26.5636 0.406375 -0.0787968 1.39457E-05 115.35 0.00177936 -24.4793 0.00239705 83.188 0.737814 8.96854 0.00107337 92.162 0.996653 26.5636 3.69748E-07 127.34 0.333732 3.98718 0.00937782 73.874 1 S VTSGGVSESPSGF CK1;GSK3 0.081 3.69748E-07 127.34 _VTSGGVpSESPSGFSK_ VTS(0.001)GGVS(0.997)ES(0.002)PSGFSK VT(-37.97)S(-30.07)GGVS(26.56)ES(-26.56)PS(-50.31)GFS(-97.13)K 7 2 753.32961 -0.19889 4362200 0 0 0 3364300 0 997870 0 75 83 286 286 6642 7604;7605 67404 41413 Mix4_TiO2_1_4 3415 67404 41413 Mix4_TiO2_1_4 3415 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.791941 5.88021 0.791941 5.88021 0.121427 42.866 0.499106 0 0.00239705 83.188 0.673535 4.26251 0.00107337 92.162 0.0653321 -11.4845 3.69748E-07 127.34 0.133254 -3.98718 0.00937782 73.874 2 S SGGVSESPSGFSK Proline-directed 0.05 0.121427 42.866 _VTpSGGVSEpSPSGFSK_ VT(0.019)S(0.981)GGVS(0.205)ES(0.792)PS(0.003)GFSK VT(-17.4)S(17.4)GGVS(-5.88)ES(5.88)PS(-24.8)GFS(-42.87)K 9 2 793.31278 0.34809 26028 26028 0 0 0 0 0 0 76 83 288 288 6642 7604;7605 67392 41404 Mix4_TiO2_1_2 2770 67388 41397 Mix4_InSol_TiO2_1 4324 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.67987 3.27155 0.67987 3.27155 1.39457E-05 115.35 0.499106 0 0.00239705 83.188 0.252411 -4.26251 0.00107337 92.162 0.0140771 -18.1507 3.69748E-07 127.34 0.133254 -3.98718 0.00937782 73.874 1 S GVSESPSGFSKHI CK1 0.143 3.69748E-07 127.34 _VTSGGVSESPpSGFSK_ VTSGGVSES(0.32)PS(0.68)GFSK VT(-99.58)S(-84.01)GGVS(-42.35)ES(-3.27)PS(3.27)GFS(-56.93)K 11 2 753.32961 0.32295 48572 48572 0 0 0 0 0 0 77 83 317 317 6807 7790 69077 42354 Mix4_TiO2_Reinj_1_4 2311 69077 42354 Mix4_TiO2_Reinj_1_4 2311 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.999915 40.6823 0.999246 31.4554 0.0498344 47.106 0.989966 20.1141 0.123991 37.049 0.999915 40.6823 0.00173281 91.923 1 S NVKYSSSQPEPRT CK2 0.117 0.00173281 91.923 _YSSpSQPEPR_ YSSS(1)QPEPR Y(-91.92)S(-77.33)S(-40.68)S(40.68)QPEPR 4 2 565.72934 -0.092574 756070 26.625 178550 14556 0 562960 0 0 0 78 86 76 76 3124 3548 29733 18517 Mix4_InSol_TiO2_1 2914 29735 18520 Mix4_TiO2_1_2 1752 O14828;O14828-2 O14828 O14828 >sp|O14828|SCAM3_HUMAN Secretory carrier-associated membrane protein 3 OS=Homo sapiens GN=SCAMP3 PE=1 SV=3;>sp|O14828-2|SCAM3_HUMAN Isoform 2 of Secretory carrier-associated membrane protein 3 OS=Homo sapiens GN=SCAMP3 0.737932 4.49603 0.727338 4.26113 0.113139 46.193 0 0 0.40182 -1.72801 0.115527 45.826 0 0 0.737932 4.49603 0.560323 19.729 0.181281 -6.54782 0.255975 34.719 1 S QPSRKLSPTEPKN CAMK2;CK1;CK2;PKA;Proline-directed 0.004788 0.113139 46.193 _KLpSPTEPK_ KLS(0.738)PT(0.262)EPK KLS(4.5)PT(-4.5)EPK 3 2 490.24663 -0.10998 346530 114210 0 0 0 0 232320 0 79 89 575 575 6185 7062 61245 37100 Mix4_InSol_TiO2_1 3905 61246 37101 Mix4_InSol_Tio2_Reinj_1 3847 O14936-4;O14936-3;O14936-5 O14936-4 O14936-4 >sp|O14936-4|CSKP_HUMAN Isoform 4 of Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK;>sp|O14936-3|CSKP_HUMAN Isoform 3 of Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK;>sp|O14936-5|CSKP_HUMAN Isoform 5 of Peripheral plasma 0.328899 0 0 0 0.00061307 -31.4932 0.00220728 81.632 0.328899 0 0.414061 31.708 1.78473E-05 -47.468 8.95135E-06 105.57 1 S PSYRTQSSSCEDL CAMK2;PKA/AKT 0.00111111 8.95135E-06 105.57 _TQpSSSCEDLPSTTQPK_ T(0.013)QS(0.329)S(0.329)S(0.329)CEDLPSTTQPK T(-14.15)QS(0)S(0)S(0)CEDLPS(-31.71)T(-31.71)T(-31.71)QPK 3 2 923.38225 1.0437 0 0 0 0 0 0 0 0 80 89 576 576 6185 7062 61245 37100 Mix4_InSol_TiO2_1 3905 61246 37101 Mix4_InSol_Tio2_Reinj_1 3847 O14936-4;O14936-3;O14936-5 O14936-4 O14936-4 >sp|O14936-4|CSKP_HUMAN Isoform 4 of Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK;>sp|O14936-3|CSKP_HUMAN Isoform 3 of Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK;>sp|O14936-5|CSKP_HUMAN Isoform 5 of Peripheral plasma 0.328899 0 0 0 0.134638 -8.07658 0.00220728 81.632 0.328899 0 0.414061 31.708 0.00371925 -24.2792 8.95135E-06 105.57 1 S SYRTQSSSCEDLP CK2 0.117 8.95135E-06 105.57 _TQpSSSCEDLPSTTQPK_ T(0.013)QS(0.329)S(0.329)S(0.329)CEDLPSTTQPK T(-14.15)QS(0)S(0)S(0)CEDLPS(-31.71)T(-31.71)T(-31.71)QPK 4 2 923.38225 1.0437 0 0 0 0 0 0 0 0 81 89 577 577 6185 7062 61246 37101 Mix4_InSol_Tio2_Reinj_1 3847 61246 37101 Mix4_InSol_Tio2_Reinj_1 3847 O14936-4;O14936-3;O14936-5 O14936-4 O14936-4 >sp|O14936-4|CSKP_HUMAN Isoform 4 of Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK;>sp|O14936-3|CSKP_HUMAN Isoform 3 of Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK;>sp|O14936-5|CSKP_HUMAN Isoform 5 of Peripheral plasma 0.99626 24.2792 0 0 0.864622 8.07658 0.00220728 81.632 0.328899 0 0.414061 31.708 0.99626 24.2792 8.95135E-06 105.57 1 S YRTQSSSCEDLPS CK1;CK2 0.117 8.95135E-06 105.57 _TQSSpSCEDLPSTTQPK_ TQSS(0.004)S(0.996)CEDLPSTTQPK T(-56.04)QS(-47.47)S(-24.28)S(24.28)CEDLPS(-71.35)T(-85.73)T(-99.07)QPK 5 2 923.38225 1.2757 186110 0 0 0 106520 0 0 79598 82 92 780 780 4673 5304 44312 27108 Mix4_TiO2_1_5 3546 44314 27112 Mix4_TiO2_Reinj_1_5 4110 O14976 O14976 O14976 >sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens GN=GAK PE=1 SV=2 0.873633 12.4719 0.873633 12.4719 1.4E-14 137.3 0 0 0.850252 7.96851 1.39767E-19 152.69 0 0 0 0 1 S EPTDSDSPPSSSA CK1;GSK3;Proline-directed 0.05 1.39767E-19 152.69 _QPGSTAQYDAGAGSPEAEPTDSDpSPPSSSADASR_ QPGSTAQYDAGAGSPEAEPT(0.01)DS(0.04)DS(0.874)PPS(0.049)S(0.012)S(0.015)ADASR QPGS(-120.33)T(-120.33)AQY(-115.61)DAGAGS(-71.93)PEAEPT(-19.5)DS(-13.42)DS(12.47)PPS(-12.47)S(-18.58)S(-17.66)ADAS(-35.55)R 24 3 1125.1253 0.088759 2666600 0.28689 884290 0 0 1782300 0 0 0 83 94 1031 1031 1514 1702 14010 8530 Mix4_TiO2_1_5 6529 14011 8531 Mix4_TiO2_Reinj_1_5 7400 O14980 O14980 O14980 >sp|O14980|XPO1_HUMAN Exportin-1 OS=Homo sapiens GN=XPO1 PE=1 SV=1 0.99964 34.4308 0.99964 34.4308 3.32521E-12 170.74 0.981521 17.2522 3.767E-22 200.16 1 S FAGEDTSDLFLEE 3.767E-22 200.16 _EFAGEDTpSDLFLEER_ EFAGEDTS(1)DLFLEER EFAGEDT(-34.43)S(34.43)DLFLEER 8 2 919.38003 -0.11664 565930 0.15775 198710 0 0 367220 0 0 0 84 94 389 389 1825;1826 2060;2062 16761 10105 Mix4_TiO2_Reinj_1_5 7348 16738 10075 Mix4_TiO2_1_5 6932 O14980 O14980 O14980 >sp|O14980|XPO1_HUMAN Exportin-1 OS=Homo sapiens GN=XPO1 PE=1 SV=1 0.605994 3.96359 0.436976 -0.439253 0.000405822 86.69 0.121481 -6.58263 1.74885 11.708 0.605994 3.96359 0.000483147 84.372 0 0 0.22996 0 2.00491 3.2817 1 S ESPFSTSASPLLS 0.000405822 86.69 _ESPFSTpSASPLLSGSQHFDVPPRR_ ES(0.006)PFS(0.019)T(0.094)S(0.606)AS(0.243)PLLS(0.016)GS(0.016)QHFDVPPRR ES(-20.06)PFS(-15.07)T(-8.12)S(3.96)AS(-3.96)PLLS(-15.74)GS(-15.74)QHFDVPPRR 7 3 893.75694 -0.446 526100 2.9614 0 0 0 526100 0 0 0 85 94 391 391 1825;1826 2060;2062 16735 10067 Mix4_TiO2_1_5 6507 16738 10075 Mix4_TiO2_1_5 6932 O14980 O14980 O14980 >sp|O14980|XPO1_HUMAN Exportin-1 OS=Homo sapiens GN=XPO1 PE=1 SV=1 0.961012 15.0318 0.961012 15.0318 0.000405822 86.69 0.55306 6.58263 1.74885 11.708 0.957395 14.5609 0.000483147 84.372 0 0 0.22996 0 2.00491 3.2817 1 S PFSTSASPLLSGS CK1;GSK3;Proline-directed 0.05 0.000405822 86.69 _ESPFSTSApSPLLSGSQHFDVPPR_ ESPFST(0.001)S(0.03)AS(0.961)PLLS(0.004)GS(0.004)QHFDVPPR ES(-50.42)PFS(-34.52)T(-28.2)S(-15.03)AS(15.03)PLLS(-24.38)GS(-24.38)QHFDVPPR 9 3 841.72324 0.25433 12227000 68.828 2164700 65348 0 9997400 0 0 0 86 96 1905 1905 130 151 1310 827 Mix4_TiO2_Reinj_1_1 5011 1310 827 Mix4_TiO2_Reinj_1_1 5011 O15027-5;O15027;O15027-3;O15027-4;O15027-2 O15027-5 O15027-5 >sp|O15027-5|SC16A_HUMAN Isoform 5 of Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A;>sp|O15027|SC16A_HUMAN Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A PE=1 SV=3;>sp|O15027-3|SC16A_HUMAN Isoform 3 of Protein transport protein Sec 0.994297 22.4161 0.949509 12.7433 0.00020103 95.466 0.994297 22.4161 2.41535E-26 189.25 0 0 0 0 1 S QPPLSLSPAPETK NEK6;Proline-directed 0.05 2.41535E-26 189.25 _ADSGPTQPPLSLpSPAPETK_ ADSGPTQPPLS(0.006)LS(0.994)PAPETK ADS(-144.63)GPT(-129.91)QPPLS(-22.42)LS(22.42)PAPET(-55.93)K 13 2 986.9668 -0.065801 661360 109960 0 0 551410 0 0 0 87 96 1786 1786 3567 4022 33628 20718 Mix4_TiO2_1_1 5471 33628 20718 Mix4_TiO2_1_1 5471 O15027-5;O15027;O15027-3;O15027-4;O15027-2 O15027-5 O15027-5 >sp|O15027-5|SC16A_HUMAN Isoform 5 of Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A;>sp|O15027|SC16A_HUMAN Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A PE=1 SV=3;>sp|O15027-3|SC16A_HUMAN Isoform 3 of Protein transport protein Sec 1 78.4778 1 78.4778 8.36212E-07 114.39 0 0 1 64.1899 1.14759E-06 112.99 1 S PDGPLASPARVPM CDK1;CDK2;Proline-directed 0.0057 8.36212E-07 114.39 _LLPSAPQTLPDGPLApSPAR_ LLPSAPQTLPDGPLAS(1)PAR LLPS(-114.39)APQT(-78.48)LPDGPLAS(78.48)PAR 16 2 991.01135 -0.015695 558010 122930 0 0 435080 0 0 0 88 96 390 390 4570 5190 43279 26542 Mix4_TiO2_1_1 3731 43280 26543 Mix4_TiO2_Reinj_1_1 4218 O15027-5;O15027;O15027-3;O15027-4;O15027-2 O15027-5 O15027-5 >sp|O15027-5|SC16A_HUMAN Isoform 5 of Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A;>sp|O15027|SC16A_HUMAN Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A PE=1 SV=3;>sp|O15027-3|SC16A_HUMAN Isoform 3 of Protein transport protein Sec 0.499991 0 0.499991 0 0.000283576 89.031 0 0 0.147957 -7.60303 3.92074E-11 127.78 0.0427582 -13.4991 5.17384E-11 124.71 0 0 1 S FFKQIDSSPVGGE 3.92074E-11 127.78 _QIDpSSPVGGETDETTVSQNYR_ QIDS(0.5)S(0.5)PVGGETDETTVSQNYR QIDS(0)S(0)PVGGET(-44.91)DET(-58.66)T(-57.96)VS(-86.15)QNY(-89.03)R 4 2 1182.0054 -0.65975 54199 54199 0 0 0 0 0 0 89 96 391 391 4570 5190 43278 26541 Mix4_InSol_TiO2_1 5054 43280 26543 Mix4_TiO2_Reinj_1_1 4218 O15027-5;O15027;O15027-3;O15027-4;O15027-2 O15027-5 O15027-5 >sp|O15027-5|SC16A_HUMAN Isoform 5 of Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A;>sp|O15027|SC16A_HUMAN Protein transport protein Sec16A OS=Homo sapiens GN=SEC16A PE=1 SV=3;>sp|O15027-3|SC16A_HUMAN Isoform 3 of Protein transport protein Sec 0.957033 13.4991 0.499991 0 0.000283576 89.031 0 0 0.851997 7.60303 3.92074E-11 127.78 0.957033 13.4991 5.17384E-11 124.71 0 0 1 S FKQIDSSPVGGET Polo box;Proline-directed 0.00405 3.92074E-11 127.78 _QIDSpSPVGGETDETTVSQNYR_ QIDS(0.043)S(0.957)PVGGETDETTVSQNYR QIDS(-13.5)S(13.5)PVGGET(-36.61)DET(-84.97)T(-90.96)VS(-124.06)QNY(-124.71)R 5 2 1182.0054 0.29673 403900 54199 0 0 224990 0 124710 0 90 101 90 90 2307 2610 21355 13081 Mix4_TiO2_1_6 3559 21356 13082 Mix4_TiO2_Reinj_1_6 4243 O15173 O15173 O15173 >sp|O15173|PGRC2_HUMAN Membrane-associated progesterone receptor component 2 OS=Homo sapiens GN=PGRMC2 PE=1 SV=1 0.991661 20.921 0.991661 20.921 0.0189685 61.746 0 0 0.990692 20.9779 7.75829E-12 104.4 1 S AGAGEESPATSLP GSK3;Proline-directed 0.05 7.75829E-12 104.4 _GLGAGAGAGEEpSPATSLPR_ GLGAGAGAGEES(0.992)PAT(0.008)SLPR GLGAGAGAGEES(20.92)PAT(-20.92)S(-34.95)LPR 12 2 889.40945 0.16558 28689 28689 0 0 0 0 0 0 91 102 447 447 2231 2524 20468 12554 Mix4_TiO2_1_3 3094 20468 12554 Mix4_TiO2_1_3 3094 O15231-3;O15231;O15231-2 O15231-3 O15231-3 >sp|O15231-3|ZN185_HUMAN Isoform 3 of Zinc finger protein 185 OS=Homo sapiens GN=ZNF185;>sp|O15231|ZN185_HUMAN Zinc finger protein 185 OS=Homo sapiens GN=ZNF185 PE=1 SV=3;>sp|O15231-2|ZN185_HUMAN Isoform 2 of Zinc finger protein 185 OS=Homo sapiens GN=ZNF1 0.640413 2.50657 0.640413 2.50657 2.90956E-11 130.23 0 0 1 S QQPADPSTPERQS CK2 0.117 2.90956E-11 130.23 _GGQGDPAVPAQQPADPpSTPER_ GGQGDPAVPAQQPADPS(0.64)T(0.36)PER GGQGDPAVPAQQPADPS(2.51)T(-2.51)PER 17 2 1077.9762 0.28346 52875 52875 0 0 0 0 0 0 92 103 148 148 4727;5811;5812 5369;6627;6628 45066 27584 Mix4_TiO2_Reinj_1_5 2408 57292 34912 Mix4_TiO2_Reinj_1_5 2967 O15234 O15234 O15234 >sp|O15234|CASC3_HUMAN Protein CASC3 OS=Homo sapiens GN=CASC3 PE=1 SV=2 1 77.8217 0.858626 8.82598 0.000554594 81.058 0 0 1 77.8217 8.94264E-12 134.37 0.879866 8.78906 5.74479E-07 99.885 0.975857 16.0964 7.55368E-07 103.23 1 S VTGERQSGDGQES PKA 0.042 8.94264E-12 134.37 _QpSGDGQESTEPVENK_ QS(1)GDGQESTEPVENK QS(77.82)GDGQES(-77.82)T(-85.69)EPVENK 2 2 842.83853 0.4249 3506000 19.96 478100 0 0 1986100 0 551180 490550 93 103 265 265 6737;6738 7710;7711 68307 41866 Mix4_TiO2_Reinj_1_5 4217 68307 41866 Mix4_TiO2_Reinj_1_5 4217 O15234 O15234 O15234 >sp|O15234|CASC3_HUMAN Protein CASC3 OS=Homo sapiens GN=CASC3 PE=1 SV=2 0.999993 51.5149 0.911591 10.133 0.0273797 59.796 0 0 0.999993 51.5149 0.0162205 67.877 0.99816 27.3442 0.0432213 56.968 0.96314 14.1714 0.165245 39.632 1 S RKPRYGSPPQRDP CAMK2;Proline-directed 0.042 0.0162205 67.877 _YGpSPPQRDPNWNGER_ YGS(1)PPQRDPNWNGER Y(-51.51)GS(51.51)PPQRDPNWNGER 3 3 618.2636 0.88363 850120 86958 0 0 359380 0 209780 194010 94 111 425 425 2349 2658 21691 13276 Mix4_TiO2_Reinj_1_4 6020 21691 13276 Mix4_TiO2_Reinj_1_4 6020 O15379-2;O15379 O15379-2 O15379-2 >sp|O15379-2|HDAC3_HUMAN Isoform RPD3-2A of Histone deacetylase 3 OS=Homo sapiens GN=HDAC3;>sp|O15379|HDAC3_HUMAN Histone deacetylase 3 OS=Homo sapiens GN=HDAC3 PE=1 SV=2 0.999998 57.9132 0 0 0.999998 57.9132 1.30002E-07 99.383 1 S HDNDKESDVEI__ CK2 0.117 1.30002E-07 99.383 _GPEENYSRPEAPNEFYDGDHDNDKEpSDVEI_ GPEENYSRPEAPNEFYDGDHDNDKES(1)DVEI GPEENY(-94.03)S(-93.16)RPEAPNEFY(-57.91)DGDHDNDKES(57.91)DVEI 26 3 1183.1409 -0.38284 1728500 0 0 0 1728500 0 0 0 95 113 464 464 174;4040 202;4602 38186 23438 Mix4_TiO2_1_3 3558 38186 23438 Mix4_TiO2_1_3 3558 O15427 O15427 O15427 >sp|O15427|MOT4_HUMAN Monocarboxylate transporter 4 OS=Homo sapiens GN=SLC16A3 PE=1 SV=1 0.99884 29.3513 0.99884 29.3513 0.000741022 106.47 0 0 0.993467 21.9105 0.00516175 84.415 0.814071 9.42344 0.0108992 71.911 0.967551 17.755 0.554908 28.089 1 S VHTPETSV_____ CK1;PLK1 0.033462 0.000741022 106.47 _NGEVVHTPETpSV_ NGEVVHTPET(0.001)S(0.999)V NGEVVHT(-87.09)PET(-29.35)S(29.35)V 11 2 674.79266 0.4386 915580 270860 0 0 353180 0 103540 188000 96 113 436 436 3472 3918 32698 20273 Mix4_TiO2_Reinj_1_5 3919 32696 20270 Mix4_TiO2_Reinj_1_4 3853 O15427 O15427 O15427 >sp|O15427|MOT4_HUMAN Monocarboxylate transporter 4 OS=Homo sapiens GN=SLC16A3 PE=1 SV=1 1 73.7241 1 35.0219 0.187058 35.022 0 0 1 73.7241 0.000169431 114.02 0 0 0 0 1 S HKPPADSGVDLRE CK2 0.117 0.000169431 114.02 _LHKPPADpSGVDLR_ LHKPPADS(1)GVDLR LHKPPADS(73.72)GVDLR 8 2 742.8665 -0.31031 2807700 32.36 32077 0 0 2775600 0 0 0 97 116 241 241 384 440 3654 2186 Mix4_TiO2_Reinj_1_5 7496 3654 2186 Mix4_TiO2_Reinj_1_5 7496 O15530;O15530-2;Q6A1A2 O15530 O15530 >sp|O15530|PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens GN=PDPK1 PE=1 SV=1;>sp|O15530-2|PDPK1_HUMAN Isoform 2 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens GN=PDPK1;>sp|Q6A1A2|PDPK2_HUMAN Putative 3-phosphoin 1 93.4037 1 75.3725 8.69123E-32 206.92 1 113.822 2.94954E-26 187.92 1 93.4037 6.35171E-59 262.43 0 0 1 81.1373 3.2863E-39 227.87 1 65.059 3.58387E-21 162.49 1 S KQARANSFVGTAQ CAMK2 0.042 6.35171E-59 262.43 _ANpSFVGTAQYVSPELLTEK_ ANS(1)FVGTAQYVSPELLTEK ANS(93.4)FVGT(-93.4)AQY(-187.08)VS(-220.6)PELLT(-262.43)EK 3 2 1067.5088 0.36266 47954000 10910000 50469 0 28479000 0 4141500 4372800 98 116 36 36 6189 7066 61277 37117 Mix4_InSol_Tio2_Reinj_1 4211 61279 37119 Mix4_TiO2_Reinj_1_4 3926 O15530;O15530-3;Q6A1A2 O15530 O15530 >sp|O15530|PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens GN=PDPK1 PE=1 SV=1;>sp|O15530-3|PDPK1_HUMAN Isoform 3 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens GN=PDPK1;>sp|Q6A1A2|PDPK2_HUMAN Putative 3-phosphoin 0.550941 1.09245 0.187991 -6.32064 0.0150674 68.899 0.132313 -8.16578 2.74588E-06 114.26 0.1273 -8.35794 0.00166702 85.861 0.550941 1.09245 0.0992446 48.879 1 S RTQTESSTPPGIP 2.74588E-06 114.26 _TQTESpSTPPGIPGGSR_ TQTES(0.02)S(0.551)T(0.428)PPGIPGGSR T(-46.78)QT(-33.7)ES(-14.32)S(1.09)T(-1.09)PPGIPGGS(-48.88)R 6 2 826.3698 0.60836 66440 0 0 0 0 0 0 66440 99 117 2443 2443 2142 2427 19689 12038 Mix4_TiO2_Reinj_1_1 3031 19689 12038 Mix4_TiO2_Reinj_1_1 3031 O43149 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6 0.5 0 0.197482 -6.08927 0.429147 35.432 0.5 0 0.121122 48.673 0 0 0 0 1 S EVERPVSSPGDPE CAMK2;CHK1;PKD 0.020748 0.121122 48.673 _GDREEEVERPVpSSPGDPEQK_ GDREEEVERPVS(0.5)S(0.5)PGDPEQK GDREEEVERPVS(0)S(0)PGDPEQK 12 3 774.00781 -0.01153 854150 0 0 0 854150 0 0 0 100 117 2444 2444 2142 2427 19688 12037 Mix4_TiO2_1_1 2672 19689 12038 Mix4_TiO2_Reinj_1_1 3031 O43149 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6 0.802518 6.08927 0.802518 6.08927 0.429147 35.432 0.5 0 0.121122 48.673 0 0 0 0 1 S VERPVSSPGDPEQ CK2;ERK/MAPK;Polo box;Proline-directed 0.0034 0.121122 48.673 _GDREEEVERPVSpSPGDPEQK_ GDREEEVERPVS(0.197)S(0.803)PGDPEQK GDREEEVERPVS(-6.09)S(6.09)PGDPEQK 13 3 774.00781 -0.12383 1012000 157820 0 0 854150 0 0 0 101 117 1518 1518 3636 4098 34174 21075 Mix4_TiO2_1_1 5095 34173 21073 Mix4_TiO2_1_1 5136 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.943494 13.7595 0.943494 13.7595 7.0506E-26 159.39 0.71033 5.37587 1.00559 36.439 0.807888 7.05614 3.8375E-18 141.37 0 0 0 0 1 S TAEEPLSPSTPTR ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 7.0506E-26 159.39 _LPSSSGLPAADVSPATAEEPLpSPSTPTR_ LPSSSGLPAADVSPATAEEPLS(0.943)PS(0.04)T(0.008)PT(0.008)R LPS(-129.2)S(-129.2)S(-133.29)GLPAADVS(-101.7)PAT(-72)AEEPLS(13.76)PS(-13.76)T(-20.5)PT(-20.5)R 22 2 1408.1735 0.61571 1879600 103470 18692 0 1757400 0 0 0 102 117 1520 1520 3636 4098 34173 21073 Mix4_TiO2_1_1 5136 34173 21073 Mix4_TiO2_1_1 5136 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.465115 0 0.465115 0 7.0506E-26 159.39 0.206003 -5.37587 1.00559 36.439 0.159124 -7.05614 3.8375E-18 141.37 0 0 0 0 1 S EEPLSPSTPTRRP NEK6 0.076 7.0506E-26 159.39 _LPSSSGLPAADVSPATAEEPLpSPSTPTR_ LPSSSGLPAADVSPATAEEPLS(0.465)PS(0.465)T(0.069)PT(0.001)R LPS(-151.7)S(-154.85)S(-154.85)GLPAADVS(-114.84)PAT(-72.71)AEEPLS(0)PS(0)T(-8.32)PT(-25.73)R 24 3 939.11809 0.091277 0 0 0 0 0 0 0 0 103 117 1463 1463 6250 7140;7141 62027 37561 Mix4_TiO2_1_1 4977 62028 37562 Mix4_TiO2_Reinj_1_1 5493 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.330613 0 0.330613 0 0.000629087 82.893 0 0 0.326411 0 0.0376351 73.966 0 0 0 0 1 S NKRQRTSSVVEEH PKA 0.042 1.38507E-18 143.27 _pTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPK_ T(0.331)S(0.331)S(0.331)VVEEHFQAS(0.008)VSPTEAAPPATGDQSPGLGTQPK T(0)S(0)S(0)VVEEHFQAS(-16.11)VS(-37.12)PT(-57.85)EAAPPAT(-72.23)GDQS(-77.3)PGLGT(-81.76)QPK 2 3 1196.5561 0.27372 0 0 0 0 0 0 0 0 104 117 1464 1464 6250 7140;7141 62027 37561 Mix4_TiO2_1_1 4977 62028 37562 Mix4_TiO2_Reinj_1_1 5493 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.330613 0 0.330613 0 0.000629087 82.893 0 0 0.326411 0 0.0376351 73.966 0 0 0 0 1 S KRQRTSSVVEEHF CAMK2;CK2;PKA/AKT 0.001764 1.38507E-18 143.27 _pTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPK_ T(0.331)S(0.331)S(0.331)VVEEHFQAS(0.008)VSPTEAAPPATGDQSPGLGTQPK T(0)S(0)S(0)VVEEHFQAS(-16.11)VS(-37.12)PT(-57.85)EAAPPAT(-72.23)GDQS(-77.3)PGLGT(-81.76)QPK 3 3 1196.5561 0.27372 0 0 0 0 0 0 0 0 105 117 1473 1473 6250 7140;7141 62028 37562 Mix4_TiO2_Reinj_1_1 5493 62028 37562 Mix4_TiO2_Reinj_1_1 5493 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.333499 1.76614 0.00809648 -16.1102 0.000629087 82.893 0 0 0.333499 1.76614 1.38507E-18 143.27 0 0 0 0 1 S EEHFQASVSPTEA 1.38507E-18 143.27 _TSSVVEEHFQApSVSPTEAAPPATGDQSPGLGTQPK_ T(0.222)S(0.222)S(0.222)VVEEHFQAS(0.333)VSPTEAAPPATGDQSPGLGTQPK T(-1.77)S(-1.77)S(-1.77)VVEEHFQAS(1.77)VS(-30.4)PT(-51.28)EAAPPAT(-125.92)GDQS(-129.16)PGLGT(-137.57)QPK 12 3 1196.5561 -0.35131 0 0 0 0 0 0 0 0 106 117 1475 1475 6250 7140;7141 62034 37563 Mix4_TiO2_Reinj_1_1 5366 62034 37563 Mix4_TiO2_Reinj_1_1 5366 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.731097 4.56618 6.4213E-05 -37.117 0.000629087 82.893 0 0 0.731097 4.56618 0.0376351 73.966 0 0 0 0 2 S HFQASVSPTEAAP CK2;Proline-directed 0.05 0.0376351 73.966 _pTSSVVEEHFQASVpSPTEAAPPATGDQSPGLGTQPK_ T(0.326)S(0.326)S(0.326)VVEEHFQAS(0.032)VS(0.731)PT(0.257)EAAPPATGDQSPGLGTQPK T(0)S(0)S(0)VVEEHFQAS(-12.02)VS(4.57)PT(-4.57)EAAPPAT(-36.72)GDQS(-45.46)PGLGT(-60.42)QPK 14 3 1223.2115 0.24612 292640 0 0 0 292640 0 0 0 107 118 828 828 1607 1804 14808 8988 Mix4_TiO2_1_5 4433 14808 8988 Mix4_TiO2_1_5 4433 O43156 O43156 O43156 >sp|O43156|TTI1_HUMAN TEL2-interacting protein 1 homolog OS=Homo sapiens GN=TTI1 PE=1 SV=3 1 82.1307 1 82.1307 4.42953E-07 107.78 0.999993 51.506 0.162108 51.506 1 S VADGNVSDFDNEE CK2 0.117 4.42953E-07 107.78 _EKDVADGNVpSDFDNEEEEQSVPPK_ EKDVADGNVS(1)DFDNEEEEQSVPPK EKDVADGNVS(82.13)DFDNEEEEQS(-82.13)VPPK 10 3 919.71855 0.10362 836160 0.5778 386260 0 0 449900 0 0 0 108 118 459 459 5075 5770 49066 29973 Mix4_TiO2_Reinj_1_5 4274 49066 29973 Mix4_TiO2_Reinj_1_5 4274 O43156 O43156 O43156 >sp|O43156|TTI1_HUMAN TEL2-interacting protein 1 homolog OS=Homo sapiens GN=TTI1 PE=1 SV=3 0.999997 55.7366 0 0 0.999997 55.7366 0.0330835 55.737 1 S SDDLNASPKTSAT CDK1;GSK3;NEK6;Proline-directed 0.0057 0.0330835 55.737 _RWNSDDLNApSPK_ RWNSDDLNAS(1)PK RWNS(-55.74)DDLNAS(55.74)PK 10 2 741.82229 0.63277 208230 0 0 0 208230 0 0 0 109 119 1549 1549 3481 3929 32808 20322 Mix4_InSol_Tio2_Reinj_1 5863 32808 20322 Mix4_InSol_Tio2_Reinj_1 5863 O43166;O43166-2 O43166 O43166 >sp|O43166|SI1L1_HUMAN Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens GN=SIPA1L1 PE=1 SV=4;>sp|O43166-2|SI1L1_HUMAN Isoform E6TP1 alpha of Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens GN=SIPA1L1 0.99988 39.2035 0.998025 27.0361 0.000155608 114.49 0 0 0.988738 19.4347 7.73356E-24 123.64 0.991238 20.5356 3.95209E-07 155.31 0.99988 39.2035 2.4144E-13 180.51 1 S KLIDLESPTPESQ Proline-directed 0.05 2.4144E-13 180.51 _LIDLEpSPTPESQK_ LIDLES(1)PTPESQK LIDLES(39.2)PT(-39.2)PES(-116.07)QK 6 2 768.86329 -0.087493 304330 90753 0 0 0 0 130240 83334 110 119 1585 1585 6083 6938 60096 36416 Mix4_InSol_TiO2_1 5102 60097 36417 Mix4_InSol_Tio2_Reinj_1 5022 O43166;O43166-2 O43166 O43166 >sp|O43166|SI1L1_HUMAN Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens GN=SIPA1L1 PE=1 SV=4;>sp|O43166-2|SI1L1_HUMAN Isoform E6TP1 alpha of Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens GN=SIPA1L1 0.98976 19.8643 0.988848 19.4779 1.83072E-08 160.66 0 0 0.98976 19.8643 3.52611E-05 133.74 0.84194 7.26461 1.31928E-08 164.93 1 S ALHRTLSDESIYN CAMK2;CHK1;CHK1/2;PKD 0.003192 1.31928E-08 164.93 _TLpSDESIYNSQR_ T(0.01)LS(0.99)DESIYNSQR T(-19.86)LS(19.86)DES(-45.45)IY(-120.4)NS(-133.74)QR 3 2 746.81941 0.42522 294100 58788 0 0 0 0 114160 121150 111 120 406 406 2226 2519 20448 12546 Mix4_InSol_TiO2_1 3702 20449 12547 Mix4_TiO2_1_4 2831 O43237 O43237 O43237 >sp|O43237|DC1L2_HUMAN Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens GN=DYNC1LI2 PE=1 SV=1 0.769243 7.81514 0.767798 7.71059 0.0282003 59.796 0 0 0 0 0.769243 7.81514 0.155059 40.804 0 0 1 S PASVPSSSPGTSV CK1 0.143 0.0282003 59.796 _GGPASVPSpSSPGTSVK_ GGPASVPS(0.127)S(0.769)S(0.102)PGT(0.001)S(0.001)VK GGPAS(-40.8)VPS(-7.82)S(7.82)S(-8.77)PGT(-30.87)S(-30.87)VK 9 2 747.84543 2.83 206110 142840 0 0 0 0 63269 0 112 120 446 446 6005 6845 59273 36016 Mix4_TiO2_Reinj_1_4 2547 59273 36016 Mix4_TiO2_Reinj_1_4 2547 O43237 O43237 O43237 >sp|O43237|DC1L2_HUMAN Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens GN=DYNC1LI2 PE=1 SV=1 0.996135 26.6963 0 0 0.996135 26.6963 0.00861819 73.866 1 S KTGSPGSPGAGGV CK1;ERK/MAPK;Proline-directed 0.0025 0.00861819 73.866 _TGSPGpSPGAGGVQSTAK_ T(0.002)GS(0.002)PGS(0.996)PGAGGVQSTAK T(-27.6)GS(-26.7)PGS(26.7)PGAGGVQS(-73.87)T(-73.87)AK 6 2 769.84596 0.74726 92646 0 0 0 92646 0 0 0 113 123 309 309 5355 6096;6097 52006 31845 Mix4_TiO2_Reinj_1_4 5279 52004 31840 Mix4_TiO2_1_4 4597 O43293 O43293 O43293 >sp|O43293|DAPK3_HUMAN Death-associated protein kinase 3 OS=Homo sapiens GN=DAPK3 PE=1 SV=1 0.603763 4.85236 0.0547546 -9.36093 6.90634E-09 128.24 0.603763 4.85236 0.00498871 77.4 0.0948344 -6.76288 0.00177003 85.055 0.0759579 -7.7081 0.00331672 78.81 1 S KEYTIKSHSSLPP 6.90634E-09 128.24 _pSHSSLPPNNSYADFER_ S(0.604)HS(0.198)S(0.198)LPPNNS(0.001)YADFER S(4.85)HS(-4.85)S(-4.85)LPPNNS(-27.15)Y(-45.97)ADFER 1 3 634.2669 0.54104 423070 0 0 0 423070 0 0 0 114 123 312 312 5355 6096;6097 52002 31837 Mix4_InSol_Tio2_Reinj_1 5550 52004 31840 Mix4_TiO2_1_4 4597 O43293 O43293 O43293 >sp|O43293|DAPK3_HUMAN Death-associated protein kinase 3 OS=Homo sapiens GN=DAPK3 PE=1 SV=1 0.975281 16.4841 0.848352 7.94061 6.90634E-09 128.24 0.836599 7.64679 0.00498871 77.4 0.8654 8.66437 0.00177003 85.055 0.975281 16.4841 0.00331672 78.81 1 S TIKSHSSLPPNNS CK1 0.081 6.90634E-09 128.24 _SHSpSLPPNNSYADFER_ S(0.003)HS(0.022)S(0.975)LPPNNSYADFER S(-25.41)HS(-16.48)S(16.48)LPPNNS(-76.02)Y(-78.81)ADFER 4 2 950.89671 0.14846 648070 127340 0 0 360740 0 88921 71075 115 124 137 137 3202 3632 30369 18888 Mix4_TiO2_Reinj_1_4 4573 30368 18887 Mix4_TiO2_1_4 4102 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.999367 29.0364 0.296186 -3.90471 6.91914E-07 118.5 0.999367 29.0364 0.0812642 50.12 2 S EDKKRPSLPSSPS AURORA;AURORA-1;AURORA-A;GSK3;PKA 0.006142092 6.91914E-07 118.5 _KRPpSLPpSSPSPGLPK_ KRPS(0.999)LPS(0.5)S(0.5)PS(0.001)PGLPK KRPS(29.04)LPS(0)S(0)PS(-25.46)PGLPK 4 3 569.94587 0.64801 544600 0 0 0 544600 0 0 0 116 124 140 140 3202 3632 30368 18887 Mix4_TiO2_1_4 4102 30368 18887 Mix4_TiO2_1_4 4102 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.647284 3.90471 0.647284 3.90471 6.91914E-07 118.5 0.499602 0 0.0812642 50.12 2 S KRPSLPSSPSPGL CK1 0.081 6.91914E-07 118.5 _KRPSLPpSSPpSPGLPK_ KRPS(0.296)LPS(0.647)S(0.111)PS(0.945)PGLPK KRPS(-3.9)LPS(3.9)S(-7.48)PS(10.76)PGLPK 7 2 854.41517 0.54959 87532 87532 0 0 0 0 0 0 117 124 141 141 3202 3632 30369 18888 Mix4_TiO2_Reinj_1_4 4573 30368 18887 Mix4_TiO2_1_4 4102 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.499602 0 0.111158 -7.47893 6.91914E-07 118.5 0.499602 0 0.0812642 50.12 2 S RPSLPSSPSPGLP CK1;ERK/MAPK;NEK6;Polo box;Proline-directed;WW GroupIV 0.0023175 6.91914E-07 118.5 _KRPpSLPpSSPSPGLPK_ KRPS(0.999)LPS(0.5)S(0.5)PS(0.001)PGLPK KRPS(29.04)LPS(0)S(0)PS(-25.46)PGLPK 8 3 569.94587 0.64801 0 0 0 0 0 0 0 0 118 124 143 143 3202 3632 30368 18887 Mix4_TiO2_1_4 4102 30368 18887 Mix4_TiO2_1_4 4102 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.945373 10.7636 0.945373 10.7636 6.91914E-07 118.5 0.00142916 -25.4596 0.0812642 50.12 2 S SLPSSPSPGLPKA CK1;Proline-directed 0.05 6.91914E-07 118.5 _KRPSLPpSSPpSPGLPK_ KRPS(0.296)LPS(0.647)S(0.111)PS(0.945)PGLPK KRPS(-3.9)LPS(3.9)S(-7.48)PS(10.76)PGLPK 10 2 854.41517 0.54959 87532 87532 0 0 0 0 0 0 119 124 68 68 5565 6341 54471 33350 Mix4_TiO2_Reinj_1_4 7876 54471 33350 Mix4_TiO2_Reinj_1_4 7876 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.999989 50.7188 0.996083 25.4133 0.0020896 78.489 0.999989 50.7188 1.54156E-12 132.65 1 S TVCKPRSPKPAAP CDK1;CHK1;ERK/MAPK;PKD;Proline-directed;WW GroupIV 0.0023175 1.54156E-12 132.65 _pSPKPAAPAAPPFSSSSGVLGTGLCELDR_ S(1)PKPAAPAAPPFSSSSGVLGTGLCELDR S(50.72)PKPAAPAAPPFS(-50.72)S(-56.91)S(-69.8)S(-82.01)GVLGT(-109.4)GLCELDR 1 3 950.45616 0.67238 1412900 355740 0 0 1057100 0 0 0 120 124 192 192 6566 7513 66487 40802 Mix4_TiO2_1_4 4357 66487 40802 Mix4_TiO2_1_4 4357 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.438643 0 0.438643 0 8.6449E-05 94.691 0 0 1 S SSTNEGSPSPPEP CK1;Proline-directed 0.05 8.6449E-05 94.691 _VQNHLPASGPTQPPVVSSTNEGpSPSPPEPTGK_ VQNHLPASGPTQPPVVS(0.002)S(0.009)T(0.009)NEGS(0.439)PS(0.439)PPEPT(0.103)GK VQNHLPAS(-71.92)GPT(-66.6)QPPVVS(-22.86)S(-16.93)T(-16.93)NEGS(0)PS(0)PPEPT(-6.31)GK 23 3 1091.8523 -1.1365 0 0 0 0 0 0 0 0 0 121 124 194 194 6566 7513 66487 40802 Mix4_TiO2_1_4 4357 66487 40802 Mix4_TiO2_1_4 4357 O43294;O43294-2 O43294 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 PE=1 SV=2;>sp|O43294-2|TGFI1_HUMAN Isoform 2 of Transforming growth factor beta-1-induced transcript 1 protein OS=Homo sapiens GN=TGFB1I1 0.438643 0 0.438643 0 8.6449E-05 94.691 0 0 1 S TNEGSPSPPEPTG CK2;Proline-directed 0.05 8.6449E-05 94.691 _VQNHLPASGPTQPPVVSSTNEGpSPSPPEPTGK_ VQNHLPASGPTQPPVVS(0.002)S(0.009)T(0.009)NEGS(0.439)PS(0.439)PPEPT(0.103)GK VQNHLPAS(-71.92)GPT(-66.6)QPPVVS(-22.86)S(-16.93)T(-16.93)NEGS(0)PS(0)PPEPT(-6.31)GK 25 3 1091.8523 -1.1365 0 0 0 0 0 0 0 0 0 122 125 439 439 5030 5721 48566 29691 Mix4_TiO2_Reinj_1_3 4868 48563 29688 Mix4_InSol_Tio2_Reinj_1 5281 O43318;O43318-2;O43318-3 O43318 O43318 >sp|O43318|M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens GN=MAP3K7 PE=1 SV=1;>sp|O43318-2|M3K7_HUMAN Isoform 1A of Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens GN=MAP3K7;>sp|O43318-3|M3K7_HUMAN Isoform 1C o 1 64.8882 0.999985 48.0935 8.24784E-07 109.87 1 64.8882 5.11705E-11 132.94 0.999121 30.5552 1.02887E-10 128.44 0.999992 51.3144 7.9866E-12 136.7 1 S GQPRRRSIQDLTV AURORA;AURORA-1;AURORA-A;CAMK2;CK2;PKA 0.004788 7.9866E-12 136.7 _RRpSIQDLTVTGTEPGQVSSR_ RRS(1)IQDLTVTGTEPGQVSSR RRS(64.89)IQDLT(-64.89)VT(-92.36)GT(-110.1)EPGQVS(-132.94)S(-132.94)R 3 3 756.37617 0.24583 1507900 88229 0 0 1103400 0 212200 103990 123 126 529 529 5581 6360 54600 33426 Mix4_TiO2_Reinj_1_4 6079 54600 33426 Mix4_TiO2_Reinj_1_4 6079 O43353;O43353-2 O43353 O43353 >sp|O43353|RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 OS=Homo sapiens GN=RIPK2 PE=1 SV=2;>sp|O43353-2|RIPK2_HUMAN Isoform 2 of Receptor-interacting serine/threonine-protein kinase 2 OS=Homo sapiens GN=RIPK2 0.970439 15.1625 0.900803 9.58129 0.00410316 111.74 0 0 0.970439 15.1625 0.00021678 144.26 1 S ILVVSRSPSLNLL Proline-directed 0.05 0.00021678 144.26 _pSPSLNLLQNK_ S(0.97)PS(0.03)LNLLQNK S(15.16)PS(-15.16)LNLLQNK 1 2 597.29993 -0.21655 277310 54.035 64433 0 0 212870 0 0 0 124 127 1233 1233 5377 6120 52271 31963 Mix4_TiO2_Reinj_1_1 8138 52271 31963 Mix4_TiO2_Reinj_1_1 8138 O43379-4;O43379 O43379-4 O43379-4 >sp|O43379-4|WDR62_HUMAN Isoform 4 of WD repeat-containing protein 62 OS=Homo sapiens GN=WDR62;>sp|O43379|WDR62_HUMAN WD repeat-containing protein 62 OS=Homo sapiens GN=WDR62 PE=1 SV=4 0.94674 12.4983 0.565635 1.14844 0.000202686 93.293 0.94674 12.4983 5.71038E-32 196.94 1 S RISRSISLGDSEG CAMK2;CHK1;CK1;CK2;GSK3;PKD 0.020748 5.71038E-32 196.94 _SIpSLGDSEGPIVATLAQPLR_ S(0.053)IS(0.947)LGDSEGPIVATLAQPLR S(-12.5)IS(12.5)LGDS(-88.12)EGPIVAT(-163.58)LAQPLR 3 2 1052.5379 0.43378 225550 33084 0 0 192470 0 0 0 125 128 169 169 4293 4884 40834 25126 Mix4_TiO2_Reinj_1_2 4164 40834 25126 Mix4_TiO2_Reinj_1_2 4164 O43399-3;O43399;O43399-4;O43399-2 O43399-3 O43399-3 >sp|O43399-3|TPD54_HUMAN Isoform 3 of Tumor protein D54 OS=Homo sapiens GN=TPD52L2;>sp|O43399|TPD54_HUMAN Tumor protein D54 OS=Homo sapiens GN=TPD52L2 PE=1 SV=2;>sp|O43399-4|TPD54_HUMAN Isoform 4 of Tumor protein D54 OS=Homo sapiens GN=TPD52L2;>sp|O43399-2 1 74.1454 0.999899 41.7327 0.0532721 47.665 1 74.1454 0.00215626 106.72 0 0 0 0 1 S NSATFKSFEDRVG CK2 0.117 0.00215626 106.72 _NSATFKpSFEDR_ NSATFKS(1)FEDR NS(-100.79)AT(-74.15)FKS(74.15)FEDR 7 2 691.29283 -0.026671 147030 22737 0 0 124290 0 0 0 126 131 495 495 5048 5742 48810 29833 Mix4_TiO2_Reinj_1_1 5517 48810 29833 Mix4_TiO2_Reinj_1_1 5517 O43432 O43432 O43432 >sp|O43432|IF4G3_HUMAN Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens GN=EIF4G3 PE=1 SV=2 1 79.0271 0.999985 48.3814 0.0737854 48.381 1 79.0271 0.00396172 79.027 1 S NLNSRRSPVPAQI CK1;PKA;Proline-directed 0.042 0.00396172 79.027 _RpSPVPAQIAITVPK_ RS(1)PVPAQIAITVPK RS(79.03)PVPAQIAIT(-79.03)VPK 2 2 778.93164 0.1085 126370 21360 0 0 105010 0 0 0 127 132 47 47 2467 2801 23187 14465 Mix4_TiO2_Reinj_1_6 7266 23187 14465 Mix4_TiO2_Reinj_1_6 7266 O43482 O43482 O43482 >sp|O43482|MS18B_HUMAN Protein Mis18-beta OS=Homo sapiens GN=OIP5 PE=1 SV=2 0.5 0 0 0 0.5 0 1.72472E-18 145.59 1 S TQVVKGSSPLGPA 1.72472E-18 145.59 _GpSSPLGPAGLGAEEPAAGPQLPSWLQPER_ GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER GS(0)S(0)PLGPAGLGAEEPAAGPQLPS(-145.59)WLQPER 2 3 983.80959 0.15488 102840 0 0 0 102840 0 0 0 128 132 48 48 2467 2801 23187 14465 Mix4_TiO2_Reinj_1_6 7266 23187 14465 Mix4_TiO2_Reinj_1_6 7266 O43482 O43482 O43482 >sp|O43482|MS18B_HUMAN Protein Mis18-beta OS=Homo sapiens GN=OIP5 PE=1 SV=2 0.5 0 0 0 0.5 0 1.72472E-18 145.59 1 S QVVKGSSPLGPAG CHK1;PKD;Polo box;Proline-directed 0.00405 1.72472E-18 145.59 _GpSSPLGPAGLGAEEPAAGPQLPSWLQPER_ GS(0.5)S(0.5)PLGPAGLGAEEPAAGPQLPSWLQPER GS(0)S(0)PLGPAGLGAEEPAAGPQLPS(-145.59)WLQPER 3 3 983.80959 0.15488 102840 0 0 0 102840 0 0 0 129 132 225 225 2837 3231 27107 16952 Mix4_TiO2_Reinj_1_6 3647 27107 16952 Mix4_TiO2_Reinj_1_6 3647 O43482 O43482 O43482 >sp|O43482|MS18B_HUMAN Protein Mis18-beta OS=Homo sapiens GN=OIP5 PE=1 SV=2 0.999999 58.7217 0.999996 54.1662 0.0134034 70.061 0.999999 58.7217 0.00731917 75.824 0 0 0 0 1 S EVTPDQSKPEN__ CK1;CK2 0.117 0.00731917 75.824 _ILSEVTPDQpSKPEN_ ILSEVTPDQS(1)KPEN ILS(-75.82)EVT(-58.72)PDQS(58.72)KPEN 10 2 818.87693 0.31177 123660 31299 0 0 92357 0 0 0 130 134 187 187 4742 5388 45254 27691 Mix4_TiO2_Reinj_1_3 3637 45253 27690 Mix4_TiO2_1_3 2918 O43572 O43572 O43572 >sp|O43572|AKA10_HUMAN A-kinase anchor protein 10, mitochondrial OS=Homo sapiens GN=AKAP10 PE=1 SV=2 0.971562 15.8009 0.386514 -2.00639 0.00173017 96.705 0.971562 15.8009 0.138705 36.627 1 S SLAEPVSPSKKHE CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00173017 96.705 _QSSLAEPVpSPSK_ QSS(0.003)LAEPVS(0.972)PS(0.026)K QS(-36.63)S(-25.6)LAEPVS(15.8)PS(-15.8)K 9 2 655.30541 0.17112 258090 0 0 0 258090 0 0 0 131 134 189 189 4742 5388 45253 27690 Mix4_TiO2_1_3 2918 45253 27690 Mix4_TiO2_1_3 2918 O43572 O43572 O43572 >sp|O43572|AKA10_HUMAN A-kinase anchor protein 10, mitochondrial OS=Homo sapiens GN=AKAP10 PE=1 SV=2 0.613486 2.00639 0.613486 2.00639 0.00173017 96.705 0.0255497 -15.8009 0.138705 36.627 1 S AEPVSPSKKHETT 0.00173017 96.705 _QSSLAEPVSPpSK_ QSSLAEPVS(0.387)PS(0.613)K QS(-96.71)S(-96.71)LAEPVS(-2.01)PS(2.01)K 11 2 655.30541 -0.012147 85486 85486 0 0 0 0 0 0 132 139 655 655 868;869;2064 979;980;2339 8234 4974 Mix4_TiO2_Reinj_1_5 4064 18918 11545 Mix4_TiO2_Reinj_1_3 3808 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 1 88.5178 1 25.7061 0.00158928 76.954 5.83266E-09 -82.3413 0.000906946 82.341 0 0 1 88.5178 0.00170727 97.5 0 0 1 51.9643 0.0319895 51.964 1 8.56161 0.00171157 76.577 1 S SRDGKFSPIQEKS Proline-directed 0.05 0.00170727 97.5 _DGKFpSPIQEK_ DGKFS(1)PIQEK DGKFS(88.52)PIQEK 5 2 614.78411 0.14171 3592300 165160 0 0 3023700 0 208710 194800 133 139 661 661 869;2064 980;2339 18918 11545 Mix4_TiO2_Reinj_1_3 3808 18918 11545 Mix4_TiO2_Reinj_1_3 3808 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 1 97.4996 1 74.3325 0.0024394 74.333 1 82.3413 0.000906946 82.341 1 97.4996 0.00170727 97.5 0.999992 51.1379 0.0344857 51.138 1 76.577 0.00171157 76.577 1 S SPIQEKSPKQALS CDK1;Proline-directed 0.0057 0.00170727 97.5 _FSPIQEKpSPK_ FSPIQEKS(1)PK FS(-97.5)PIQEKS(97.5)PK 8 2 620.8023 0.040667 3728100 558260 44818 0 2129000 0 575620 420400 134 139 375 375 1409 1583 13169 8085 Mix4_TiO2_Reinj_1_5 8960 13169 8085 Mix4_TiO2_Reinj_1_5 8960 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.401033 0 0.193725 -1.81913 0.0522328 67.584 0.401033 0 0.0357931 71.365 1 S ISAALVSPATSQS GSK3;Proline-directed 0.05 0.0357931 71.365 _EAPPVVPPLANAISAALVpSPATSQSIAPPVPLK_ EAPPVVPPLANAISAALVS(0.401)PAT(0.106)S(0.401)QS(0.092)IAPPVPLK EAPPVVPPLANAIS(-48.87)AALVS(0)PAT(-5.77)S(0)QS(-6.41)IAPPVPLK 19 4 821.44918 -0.31788 0 0 0 0 0 0 0 0 135 139 379 379 1409 1583 13167 8083 Mix4_TiO2_1_5 8425 13169 8085 Mix4_TiO2_Reinj_1_5 8960 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.640524 6.72974 0.640524 6.72974 0.0522328 67.584 0.401033 0 0.0357931 71.365 1 S LVSPATSQSIAPP CK1 0.143 0.0357931 71.365 _EAPPVVPPLANAISAALVSPATpSQSIAPPVPLK_ EAPPVVPPLANAIS(0.003)AALVS(0.084)PAT(0.136)S(0.641)QS(0.136)IAPPVPLK EAPPVVPPLANAIS(-23.03)AALVS(-8.81)PAT(-6.73)S(6.73)QS(-6.73)IAPPVPLK 23 4 821.44918 -0.37343 319520 319520 0 0 0 0 0 0 136 139 381 381 1409 1583 13168 8084 Mix4_TiO2_1_5 8462 13169 8085 Mix4_TiO2_Reinj_1_5 8960 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.294509 0.503057 0.294509 0.503057 0.0522328 67.584 0.0916193 -6.41193 0.0357931 71.365 1 S SPATSQSIAPPVP 0.0357931 71.365 _EAPPVVPPLANAISAALVSPATSQpSIAPPVPLK_ EAPPVVPPLANAIS(0.005)AALVS(0.194)PAT(0.245)S(0.262)QS(0.295)IAPPVPLK EAPPVVPPLANAIS(-18.14)AALVS(-1.82)PAT(-0.8)S(-0.5)QS(0.5)IAPPVPLK 25 3 1094.9298 0.30335 0 0 0 0 0 0 0 0 137 139 307 307 3475 3922 32737 20282 Mix4_TiO2_Reinj_1_5 4265 32736 20281 Mix4_TiO2_Reinj_1_5 3957 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.799657 6.0113 0.378357 -0.532394 0.758396 23.292 0.493351 0 1.01809 15.693 0.799657 6.0113 0.000256003 95.787 1 S HQVVETSHEDLPA CK2 0.117 0.000256003 95.787 _LHQVVETpSHEDLPASQER_ LHQVVET(0.2)S(0.8)HEDLPASQER LHQVVET(-6.01)S(6.01)HEDLPAS(-62.01)QER 8 3 718.9987 -1.42 220110 0 0 0 220110 0 0 0 138 139 314 314 3475 3922 32736 20281 Mix4_TiO2_Reinj_1_5 3957 32736 20281 Mix4_TiO2_Reinj_1_5 3957 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 1 70.7954 0.990715 23.2919 0.758396 23.292 0.0132989 -15.6934 1.01809 15.693 1 70.7954 0.000256003 95.787 1 S HEDLPASQERSEV GSK3;NEK6 0.076 0.000256003 95.787 _LHQVVETSHEDLPApSQER_ LHQVVETSHEDLPAS(1)QER LHQVVET(-70.8)S(-73.18)HEDLPAS(70.8)QER 15 3 718.9987 -0.23076 336250 44783 0 0 291460 0 0 0 139 139 563 563 3631 4092 34127 21059 Mix4_TiO2_Reinj_1_3 7848 34128 21060 Mix4_TiO2_Reinj_1_5 7678 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 1 78.9911 0 0 0 0 1 78.9911 0.000207071 90.089 0 0 1 S SVSRLPSKPKEEV CAMK2;CHK1;CK1;PKD 0.020748 0.000207071 90.089 _LPpSKPKEEVPHAEEFLDDSTVWGIR_ LPS(1)KPKEEVPHAEEFLDDSTVWGIR LPS(78.99)KPKEEVPHAEEFLDDS(-78.99)T(-80.64)VWGIR 3 3 987.14609 0.22569 5439800 0 0 0 5439800 0 0 0 140 139 679 679 3731 4208 35204 21782 Mix4_TiO2_Reinj_1_5 7162 35204 21782 Mix4_TiO2_Reinj_1_5 7162 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.999038 30.1646 0 0 0.999038 30.1646 0.0588387 56.615 1 S ASLLRLSQPAAGG NEK6;PKA 0.042 0.0588387 56.615 _LpSQPAAGGVLTCEAELGVEACR_ LS(0.999)QPAAGGVLT(0.001)CEAELGVEACR LS(30.16)QPAAGGVLT(-30.16)CEAELGVEACR 2 3 790.02728 1.111 50966 0 0 0 50966 0 0 0 141 139 596 596 5560;6055 6335;6906;6907 54439 33331 Mix4_TiO2_Reinj_1_5 6942 54434 33325 Mix4_TiO2_1_5 6109 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 1 80.9645 1 68.0284 1.96186E-15 145.53 0 0 1 80.9645 1.85399E-06 112.91 0 0 0.0150124 -17.5204 0.0905098 57.003 0 0 1 S LAPSPKSPGDFTS CK1;CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.96186E-15 145.53 _pSPGDFTSAAQLASTPFHK_ S(1)PGDFTSAAQLASTPFHK S(80.96)PGDFT(-80.96)S(-88.51)AAQLAS(-112.91)T(-112.91)PFHK 1 2 971.44076 0.49183 7864900 1913200 0 0 5951700 0 0 0 142 139 593 593 6055 6906;6907 59786 36266 Mix4_TiO2_Reinj_1_5 7100 59786 36266 Mix4_TiO2_Reinj_1_5 7100 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.98901 23.0386 0.854351 7.19096 0.36891 43.707 0.98901 23.0386 0.00336983 76.972 0.131463 -8.09683 0.0905098 57.003 0 0 2 S NKTLAPSPKSPGD CDK1;CK1;NEK6;Proline-directed 0.0057 0.00336983 76.972 _TLAPpSPKpSPGDFTSAAQLASTPFHK_ T(0.01)LAPS(0.989)PKS(0.964)PGDFT(0.019)S(0.019)AAQLASTPFHK T(-23.04)LAPS(23.04)PKS(18.24)PGDFT(-18.24)S(-18.24)AAQLAS(-76.97)T(-76.97)PFHK 5 3 906.0855 -0.33992 2415900 330420 0 0 2085500 0 0 0 143 142 182 182 1036 1162;1163 9763 5953 Mix4_TiO2_1_2 4747 9796 5997 Mix4_TiO2_Reinj_1_2 6438 O43741 O43741 O43741 >sp|O43741|AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens GN=PRKAB2 PE=1 SV=1 0.841345 8.02876 0.841345 8.02876 3.69764E-10 129.41 0.360111 0 1.37925E-15 148.84 0 0 0.522849 3.4105 2.1131E-07 117.52 0.426501 -0.486289 2.84416E-10 131.25 1 S TSCRDLSSSPPGP CAMK2 0.042 1.37925E-15 148.84 _DLpSSSPPGPYGQEM(ox)YAFR_ DLS(0.841)S(0.132)S(0.026)PPGPYGQEMYAFR DLS(8.03)S(-8.03)S(-15.07)PPGPY(-47.21)GQEMY(-120.72)AFR 3 2 1049.4348 -0.19463 1661000 1591600 0 0 0 0 69310 0 144 142 183 183 1036 1162;1163 9768 5970 Mix4_TiO2_Reinj_1_2 5509 9796 5997 Mix4_TiO2_Reinj_1_2 6438 O43741 O43741 O43741 >sp|O43741|AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens GN=PRKAB2 PE=1 SV=1 0.819811 9.59037 0.728196 7.29606 3.69764E-10 129.41 0.819811 9.59037 1.37925E-15 148.84 0 0 0.476275 1.19622 2.1131E-07 117.52 0.477034 0.486289 2.84416E-10 131.25 1 S SCRDLSSSPPGPY 1.37925E-15 148.84 _DLSpSSPPGPYGQEM(ox)YAFR_ DLS(0.09)S(0.82)S(0.09)PPGPYGQEMYAFR DLS(-9.59)S(9.59)S(-9.59)PPGPY(-49.44)GQEMY(-102.63)AFR 4 2 1049.4348 -0.39786 4020900 15129 0 0 4005700 0 0 0 145 142 184 184 1036 1162;1163 9769 5974 Mix4_TiO2_Reinj_1_2 5551 9796 5997 Mix4_TiO2_Reinj_1_2 6438 O43741 O43741 O43741 >sp|O43741|AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens GN=PRKAB2 PE=1 SV=1 0.99756 28.9468 0.889296 9.60499 3.69764E-10 129.41 0.99756 28.9468 1.37925E-15 148.84 0 0 0.891684 9.61919 2.1131E-07 117.52 0.789761 5.83105 2.84416E-10 131.25 1 S CRDLSSSPPGPYG NEK6;Polo box;Proline-directed 0.00405 1.37925E-15 148.84 _DLSSpSPPGPYGQEM(ox)YAFR_ DLS(0.001)S(0.001)S(0.998)PPGPYGQEMYAFR DLS(-29.48)S(-28.95)S(28.95)PPGPY(-43.45)GQEMY(-135.53)AFR 5 3 699.95897 -0.15295 4466500 350110 0 0 2387200 0 886590 842620 146 142 39 39 2844 3239;3240 27139 16969 Mix4_InSol_TiO2_1 8012 27148 16980 Mix4_TiO2_Reinj_1_2 6306 O43741 O43741 O43741 >sp|O43741|AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens GN=PRKAB2 PE=1 SV=1 0.933587 11.4791 0.914378 10.2856 1.64879E-15 147.29 0 0 0.925656 10.9521 8.50732E-21 157.68 0.933587 11.4791 0.00139517 81.897 0.499995 0 6.14373E-06 100.88 1 S HKIMVGSTDDPSV CK2 0.117 8.50732E-21 157.68 _IMVGpSTDDPSVFSLPDSK_ IMVGS(0.934)T(0.066)DDPSVFSLPDSK IMVGS(11.48)T(-11.48)DDPS(-61)VFS(-81.9)LPDS(-81.9)K 5 2 987.94194 0.12438 2354300 772240 0 0 1307100 0 133980 140970 147 142 108 108 5347 6088 51920 31779 Mix4_TiO2_Reinj_1_6 6772 51918 31776 Mix4_TiO2_Reinj_1_4 7831 O43741 O43741 O43741 >sp|O43741|AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens GN=PRKAB2 PE=1 SV=1 1 103.901 1 105.246 2.88881E-06 105.25 1 103.901 4.39476E-21 159.42 0 0 1 S KIPLIKSHNDFVA CK2;NEK6 0.076 4.39476E-21 159.42 _pSHNDFVAILDLPEGEHQYK_ S(1)HNDFVAILDLPEGEHQYK S(103.9)HNDFVAILDLPEGEHQY(-103.9)K 1 3 764.6826 -0.047691 5020000 497710 0 0 4522300 0 0 0 148 144 245 245 2013 2281 18482 11203 Mix4_InSol_TiO2_1 6260 18482 11203 Mix4_InSol_TiO2_1 6260 O43815;O43815-2 O43815 O43815 >sp|O43815|STRN_HUMAN Striatin OS=Homo sapiens GN=STRN PE=1 SV=4;>sp|O43815-2|STRN_HUMAN Isoform 2 of Striatin OS=Homo sapiens GN=STRN 0.999655 34.6224 0 0 0 0 0.999655 34.6224 0.0950766 54.127 0 0 1 S SAAADFSDEDEDD CK2 0.117 0.0950766 54.127 _FLESAAADFpSDEDEDDDVDGREK_ FLESAAADFS(1)DEDEDDDVDGREK FLES(-34.62)AAADFS(34.62)DEDEDDDVDGREK 10 3 885.67998 -0.38879 124260 0 0 0 0 0 124260 0 149 145 136 136 352 401 3297 1981 Mix4_TiO2_Reinj_1_2 4255 3297 1981 Mix4_TiO2_Reinj_1_2 4255 O43822;O43822-2 O43822 O43822 >sp|O43822|CU002_HUMAN Uncharacterized protein C21orf2 OS=Homo sapiens GN=C21orf2 PE=1 SV=1;>sp|O43822-2|CU002_HUMAN Isoform Short of Uncharacterized protein C21orf2 OS=Homo sapiens GN=C21orf2 1 98.2054 1 91.2869 1.60249E-06 120.63 1 98.2054 1.29204E-06 123.9 0 0 1 S ELSRALSEGEEIT CAMK2;CHK1;CHK1/2;CK1;CK2;PKD 0.003192 1.29204E-06 123.9 _ALpSEGEEITAAPER_ ALS(1)EGEEITAAPER ALS(98.21)EGEEIT(-98.21)AAPER 3 2 776.84817 0.34453 367280 96318 0 0 270960 0 0 0 150 145 177 177 3322 3758 31369 19447 Mix4_TiO2_Reinj_1_2 5949 31369 19447 Mix4_TiO2_Reinj_1_2 5949 O43822;O43822-2 O43822 O43822 >sp|O43822|CU002_HUMAN Uncharacterized protein C21orf2 OS=Homo sapiens GN=C21orf2 PE=1 SV=1;>sp|O43822-2|CU002_HUMAN Isoform Short of Uncharacterized protein C21orf2 OS=Homo sapiens GN=C21orf2 0.939223 12.7572 0 0 0.939223 12.7572 4.82671E-19 141.69 0 0 0 0 1 S GRDPLDSEEEATS CK2 0.117 4.82671E-19 141.69 _LCCTLSSLSSAAETGRDPLDpSEEEATSGAQDER_ LCCTLSSLSSAAETGRDPLDS(0.939)EEEAT(0.05)S(0.011)GAQDER LCCT(-117.17)LS(-98.81)S(-96.41)LS(-90.45)S(-80.36)AAET(-63.25)GRDPLDS(12.76)EEEAT(-12.76)S(-19.31)GAQDER 21 3 1208.1767 -0.59748 241710 0 0 0 241710 0 0 0 151 147 94 94 4892 5563 46989 28741 Mix4_TiO2_1_5 3655 46989 28741 Mix4_TiO2_1_5 3655 O43847-2;O43847 O43847-2 O43847-2 >sp|O43847-2|NRDC_HUMAN Isoform NRD2 of Nardilysin OS=Homo sapiens GN=NRD1;>sp|O43847|NRDC_HUMAN Nardilysin OS=Homo sapiens GN=NRD1 PE=1 SV=2 0.999957 43.7008 0.999957 43.7008 0.00414606 78.829 0.998787 29.1565 0.0121517 71.271 1 S EEGRRGSLSNAGD AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.00111111 0.00414606 78.829 _RGpSLSNAGDPEIVK_ RGS(1)LSNAGDPEIVK RGS(43.7)LS(-43.7)NAGDPEIVK 3 2 761.86669 0.65179 525120 121240 0 0 403880 0 0 0 152 151 1181 1181 5910 6741 58286 35378 Mix4_TiO2_Reinj_1_5 3830 58286 35378 Mix4_TiO2_Reinj_1_5 3830 O43933 O43933 O43933 >sp|O43933|PEX1_HUMAN Peroxisome biogenesis factor 1 OS=Homo sapiens GN=PEX1 PE=1 SV=1 0.612347 1.98555 0 0 0.612347 1.98555 4.93552E-12 168.22 1 S PVLRTASQEGCQE CAMK2;CHK1;PKD 0.020748 4.93552E-12 168.22 _TApSQEGCQELTQEQR_ T(0.388)AS(0.612)QEGCQELTQEQR T(-1.99)AS(1.99)QEGCQELT(-168.22)QEQR 3 2 922.87766 -0.26408 67624 1.7062 0 0 0 67624 0 0 0 153 154 116 116 6162 7035 61016 36982 Mix4_TiO2_Reinj_1_5 2934 61016 36982 Mix4_TiO2_Reinj_1_5 2934 O60264 O60264 O60264 >sp|O60264|SMCA5_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens GN=SMARCA5 PE=1 SV=1 0.994886 22.8905 0.916096 10.3816 0.0697709 78.382 0 0 0.994886 22.8905 0.0697709 78.382 0.936795 11.949 0.325057 24.402 0.953733 13.1638 0.222301 36.051 1 S AQKTPTSPLKMKP CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0697709 78.382 _TPTpSPLK_ TPT(0.005)S(0.995)PLK T(-78.38)PT(-22.89)S(22.89)PLK 4 2 412.20169 0.12303 401770 60117 0 0 266690 0 36272 38694 154 155 183 183 3474 3921 32726 20277 Mix4_TiO2_Reinj_1_1 2336 32726 20277 Mix4_TiO2_Reinj_1_1 2336 O60271-7;O60271;O60271-2;O60271-4;O60271-3;O60271-5 O60271-7 O60271-7 >sp|O60271-7|JIP4_HUMAN Isoform 7 of C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens GN=SPAG9;>sp|O60271|JIP4_HUMAN C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens GN=SPAG9 PE=1 SV=4;>sp|O60271-2|JIP4_HUMAN Isoform 2 of 0.813557 6.69382 0.813557 6.69382 0.11839 46.582 2 S TKLHQLSGSDQLE CK2 0.117 0.11839 46.582 _LHQLpSGSDQLEpSTAHSR_ LHQLS(0.814)GS(0.186)DQLES(0.539)T(0.459)AHS(0.002)R LHQLS(6.69)GS(-6.69)DQLES(0.92)T(-0.92)AHS(-24.58)R 5 2 1013.425 -0.70107 93197 0 0 0 93197 0 0 0 155 155 190 190 3474 3921 32726 20277 Mix4_TiO2_Reinj_1_1 2336 32726 20277 Mix4_TiO2_Reinj_1_1 2336 O60271-7;O60271;O60271-2;O60271-4;O60271-3;O60271-5 O60271-7 O60271-7 >sp|O60271-7|JIP4_HUMAN Isoform 7 of C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens GN=SPAG9;>sp|O60271|JIP4_HUMAN C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens GN=SPAG9 PE=1 SV=4;>sp|O60271-2|JIP4_HUMAN Isoform 2 of 0.538698 0.917245 0.538698 0.917245 0.11839 46.582 2 S GSDQLESTAHSRI GSK3 0.081 0.11839 46.582 _LHQLpSGSDQLEpSTAHSR_ LHQLS(0.814)GS(0.186)DQLES(0.539)T(0.459)AHS(0.002)R LHQLS(6.69)GS(-6.69)DQLES(0.92)T(-0.92)AHS(-24.58)R 12 2 1013.425 -0.70107 93197 0 0 0 93197 0 0 0 156 156 388 388 1693 1902 15483 9341 Mix4_TiO2_1_3 3586 15483 9341 Mix4_TiO2_1_3 3586 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.962512 14.0952 0.962512 14.0952 3.91811E-16 154.43 0.767763 5.19297 6.41169E-10 123.53 1 S QDAVPESPSKLSS CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 3.91811E-16 154.43 _ENDFAQSGQDAVPEpSPSK_ ENDFAQSGQDAVPES(0.963)PS(0.037)K ENDFAQS(-117.63)GQDAVPES(14.1)PS(-14.1)K 15 2 993.40985 -0.10027 1748100 3.4081 435220 0 0 1312900 0 0 0 157 156 390 390 1693 1902 15484 9342 Mix4_TiO2_1_5 3668 15483 9341 Mix4_TiO2_1_3 3586 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.99547 23.4195 0.99547 23.4195 3.91811E-16 154.43 0.474927 -0.43592 6.41169E-10 123.53 1 S AVPESPSKLSSKR GSK3 0.081 3.91811E-16 154.43 _ENDFAQSGQDAVPESPpSK_ ENDFAQSGQDAVPES(0.005)PS(0.995)K ENDFAQS(-61.71)GQDAVPES(-23.42)PS(23.42)K 17 2 993.40985 -0.30789 31209 0.060844 31209 0 0 0 0 0 0 158 156 603 603 5148 5861 49909 30518 Mix4_TiO2_Reinj_1_3 8165 49909 30518 Mix4_TiO2_Reinj_1_3 8165 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.980992 17.1272 0 0 0.980992 17.1272 9.03447E-07 100.31 1 S RIRSCVSAENFLQ CK1 0.081 9.03447E-07 100.31 _SCVpSAENFLQIQDFEGLQNRPR_ S(0.019)CVS(0.981)AENFLQIQDFEGLQNRPR S(-17.13)CVS(17.13)AENFLQIQDFEGLQNRPR 4 3 896.74605 -0.0034267 1965600 0 0 0 1965600 0 0 0 159 156 411 411 5357 6099 52023 31855 Mix4_TiO2_Reinj_1_5 7911 52022 31854 Mix4_TiO2_Reinj_1_3 8095 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.770203 8.26726 0.333326 0 5.10206E-05 97.473 0.770203 8.26726 1.18468E-05 98.552 1 S SNSEHRSHSTGFI CK1 0.143 1.18468E-05 98.552 _pSHSTGFIEGVVGPALPSTFK_ S(0.77)HS(0.115)T(0.115)GFIEGVVGPALPSTFK S(8.27)HS(-8.27)T(-8.27)GFIEGVVGPALPS(-38.25)T(-38.25)FK 1 3 704.34515 -0.71689 61821 0 0 0 61821 0 0 0 160 156 444 444 6011;6012 6853;6854;6855 59374 36048 Mix4_InSol_TiO2_1 6556 59376 36050 Mix4_TiO2_Reinj_1_3 6185 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.499968 0 0.025109 -15.8913 3.83622E-16 147.23 0 0 0.00154573 -28.1019 1.12433E-12 150.91 0.499968 0 0.208452 38.928 0.00173129 -27.5907 0.366891 36.874 1 S TGVLLPSSPEAEV CK2;NEK6 0.076 1.12433E-12 150.91 _TGVLLPpSSPEAEVPGK_ TGVLLPS(0.5)S(0.5)PEAEVPGK T(-38.93)GVLLPS(0)S(0)PEAEVPGK 7 2 830.91331 -0.011468 18818 0 0 0 0 0 18818 0 161 156 445 445 6011;6012 6853;6854;6855 59376 36050 Mix4_TiO2_Reinj_1_3 6185 59376 36050 Mix4_TiO2_Reinj_1_3 6185 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.998454 28.1019 0.974891 15.8913 3.83622E-16 147.23 0 0 0.998454 28.1019 1.12433E-12 150.91 0.529613 0.542652 1.23476 15.992 0.00393911 -24.0204 0.366891 36.874 1 S GVLLPSSPEAEVP ERK/MAPK;NEK6;Polo box;Proline-directed;WW GroupIV 0.0023175 1.12433E-12 150.91 _TGVLLPSpSPEAEVPGK_ TGVLLPS(0.002)S(0.998)PEAEVPGK T(-135.51)GVLLPS(-28.1)S(28.1)PEAEVPGK 8 2 830.91331 0.34498 680730 179460 0 0 482450 0 18818 0 162 156 455 455 6012 6854;6855 59394 36056 Mix4_TiO2_1_3 5740 59394 36056 Mix4_TiO2_1_3 5740 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 1 80.3912 1 80.3912 3.83622E-16 147.23 0 0 0.998392 30.9413 0.0142982 64.092 0.961932 15.9919 1.23476 15.992 0.994125 24.0204 0.366891 36.874 1 S EVPGKLSPKQSAT CDK1;GSK3;Proline-directed 0.0057 3.83622E-16 147.23 _TGVLLPSSPEAEVPGKLpSPK_ TGVLLPSSPEAEVPGKLS(1)PK T(-147.23)GVLLPS(-99.31)S(-80.39)PEAEVPGKLS(80.39)PK 18 2 1043.5452 -0.051885 1584900 450190 0 0 953250 0 0 181460 163 158 1364 1364 1923 2174 17649 10552 Mix4_TiO2_Reinj_1_5 3016 17649 10552 Mix4_TiO2_Reinj_1_5 3016 O60292 O60292 O60292 >sp|O60292|SI1L3_HUMAN Signal-induced proliferation-associated 1-like protein 3 OS=Homo sapiens GN=SIPA1L3 PE=1 SV=3 0.999999 60.845 0.930612 11.2749 0.705393 11.275 0 0 0.999999 60.845 0.0204496 60.845 0 0 0.928975 11.1659 0.70858 11.166 0 0 1 S DRRREVSPAPAVA CAMK2;PKA/AKT;Proline-directed 0.001764 0.0204496 60.845 _EVpSPAPAVAGQSK_ EVS(1)PAPAVAGQSK EVS(60.84)PAPAVAGQS(-60.84)K 3 2 660.8134 0.66631 292320 25794 0 0 187970 0 78561 0 164 158 170 170 5736 6537 56388 34441 Mix4_InSol_TiO2_1 5666 56388 34441 Mix4_InSol_TiO2_1 5666 O60292 O60292 O60292 >sp|O60292|SI1L3_HUMAN Signal-induced proliferation-associated 1-like protein 3 OS=Homo sapiens GN=SIPA1L3 PE=1 SV=3 0.332715 0 0 0 0 0 0.332715 0 0.00103999 81.111 0 0 1 S LPLRHRSSSEITL CAMK2;CK2 0.042 0.00103999 81.111 _pSSSEITLSECDAEDAGEPR_ S(0.333)S(0.333)S(0.333)EIT(0.002)LSECDAEDAGEPR S(0)S(0)S(0)EIT(-22.59)LS(-41.56)ECDAEDAGEPR 1 2 1066.9199 1.3147 0 0 0 0 0 0 0 0 165 158 171 171 5736 6537 56388 34441 Mix4_InSol_TiO2_1 5666 56388 34441 Mix4_InSol_TiO2_1 5666 O60292 O60292 O60292 >sp|O60292|SI1L3_HUMAN Signal-induced proliferation-associated 1-like protein 3 OS=Homo sapiens GN=SIPA1L3 PE=1 SV=3 0.332715 0 0 0 0 0 0.332715 0 0.00103999 81.111 0 0 1 S PLRHRSSSEITLS PKA 0.042 0.00103999 81.111 _pSSSEITLSECDAEDAGEPR_ S(0.333)S(0.333)S(0.333)EIT(0.002)LSECDAEDAGEPR S(0)S(0)S(0)EIT(-22.59)LS(-41.56)ECDAEDAGEPR 2 2 1066.9199 1.3147 0 0 0 0 0 0 0 0 166 158 172 172 5736 6537 56388 34441 Mix4_InSol_TiO2_1 5666 56388 34441 Mix4_InSol_TiO2_1 5666 O60292 O60292 O60292 >sp|O60292|SI1L3_HUMAN Signal-induced proliferation-associated 1-like protein 3 OS=Homo sapiens GN=SIPA1L3 PE=1 SV=3 0.332715 0 0 0 0 0 0.332715 0 0.00103999 81.111 0 0 1 S LRHRSSSEITLSE CAMK2;PKA/AKT 0.001764 0.00103999 81.111 _pSSSEITLSECDAEDAGEPR_ S(0.333)S(0.333)S(0.333)EIT(0.002)LSECDAEDAGEPR S(0)S(0)S(0)EIT(-22.59)LS(-41.56)ECDAEDAGEPR 3 2 1066.9199 1.3147 0 0 0 0 0 0 0 0 167 159 655 655 207 239 2140 1407 Mix4_TiO2_1_1 4189 2140 1407 Mix4_TiO2_1_1 4189 O60293;O60293-2 O60293 O60293 >sp|O60293|ZC3H1_HUMAN Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 PE=1 SV=3;>sp|O60293-2|ZC3H1_HUMAN Isoform 2 of Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 0.99923 33.5987 0.99923 33.5987 0.00645256 75.237 0 0 0.997165 25.6654 0.0158889 68.62 0.905934 9.96805 0.615495 40.975 0.940301 12.4279 0.844465 37.45 1 S SNSDPPSPPVLNN CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00645256 75.237 _AFKPEETSSNSDPPpSPPVLNNSHPVPR_ AFKPEETSSNSDPPS(0.999)PPVLNNSHPVPR AFKPEET(-58.25)S(-53.46)S(-53.46)NS(-34.91)DPPS(33.6)PPVLNNS(-33.6)HPVPR 15 3 994.13274 -0.989 1604500 193530 0 0 931940 0 298770 180240 168 159 662 662 207 239 2139 1405 Mix4_InSol_Tio2_Reinj_1 5548 2140 1407 Mix4_TiO2_1_1 4189 O60293;O60293-2 O60293 O60293 >sp|O60293|ZC3H1_HUMAN Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 PE=1 SV=3;>sp|O60293-2|ZC3H1_HUMAN Isoform 2 of Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 0.486619 0 0.00338504 -24.6896 0.00645256 75.237 0 0 0.00794657 -20.9555 0.0158889 68.62 0.166751 -6.94881 0.615495 40.975 0.486619 0 0.844465 37.45 1 S PPVLNNSHPVPRS NEK6 0.076 0.00645256 75.237 _AFKPEETSSNSDPPpSPPVLNNSHPVPR_ AFKPEET(0.002)S(0.002)S(0.005)NS(0.018)DPPS(0.487)PPVLNNS(0.487)HPVPR AFKPEET(-23.43)S(-23.43)S(-20.21)NS(-14.39)DPPS(0)PPVLNNS(0)HPVPR 22 4 745.85137 -0.24842 0 0 0 0 0 0 0 0 169 159 948 948 3358 3798;3799 31642 19568 Mix4_InSol_Tio2_Reinj_2 2241 31645 19573 Mix4_TiO2_Reinj_1_1 2703 O60293;O60293-2 O60293 O60293 >sp|O60293|ZC3H1_HUMAN Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 PE=1 SV=3;>sp|O60293-2|ZC3H1_HUMAN Isoform 2 of Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 0.885779 10.6423 0.168458 -6.9255 0.000996422 78.782 0 0 0.174205 -9.09226 0.495494 13.138 0 0 0 0 0.885779 10.6423 0.412863 16.706 1 S KMMRLDSSPVSSP CAMK2;CHK1;GSK3 0.0228 0.00134651 90.667 _LDpSSPVSSPR_ LDS(0.886)S(0.076)PVS(0.019)S(0.019)PR LDS(10.64)S(-10.64)PVS(-16.71)S(-16.71)PR 3 2 562.75281 0.10741 11602 0 0 0 0 0 0 11602 170 159 949 949 3358 3798;3799 31645 19573 Mix4_TiO2_Reinj_1_1 2703 31645 19573 Mix4_TiO2_Reinj_1_1 2703 O60293;O60293-2 O60293 O60293 >sp|O60293|ZC3H1_HUMAN Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 PE=1 SV=3;>sp|O60293-2|ZC3H1_HUMAN Isoform 2 of Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 0.987798 19.1207 0.841053 7.2362 0.000996422 78.782 0 0 0.987798 19.1207 0.00134651 90.667 0 0 0 0 0.0764011 -10.6423 0.412863 16.706 1 S MMRLDSSPVSSPR GSK3;NEK6;Polo box;Proline-directed 0.00405 0.00134651 90.667 _LDSpSPVSSPR_ LDS(0.012)S(0.988)PVSSPR LDS(-19.12)S(19.12)PVS(-39.72)S(-57.27)PR 4 2 562.75281 0.25289 526010 113480 0 0 412530 0 0 0 171 159 352 352 4922 5596 47242 28853 Mix4_InSol_Tio2_Reinj_1 5751 47243 28854 Mix4_TiO2_1_1 4256 O60293;O60293-2 O60293 O60293 >sp|O60293|ZC3H1_HUMAN Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 PE=1 SV=3;>sp|O60293-2|ZC3H1_HUMAN Isoform 2 of Zinc finger C3H1 domain-containing protein OS=Homo sapiens GN=ZFC3H1 0.999129 31.5217 0.981737 19.6875 0.00966008 63.256 0 0 0.99847 29.0891 0.0506798 48.434 0.999129 31.5217 0.0605703 45.501 1 S NLTRRISTSDILS CAMK2;CHK1;CHK1/2;CK1;CK2;PKA;PKA/AKT;PKD 0.00111111 0.00966008 63.256 _RIpSTSDILSEK_ RIS(0.999)T(0.001)SDILSEK RIS(31.52)T(-31.52)S(-38.56)DILS(-45.5)EK 3 2 664.82651 0.20371 422090 107320 0 0 0 0 181050 133710 172 162 527 527 3148 3574 29919 18612 Mix4_TiO2_1_5 4887 29919 18612 Mix4_TiO2_1_5 4887 O60318 O60318 O60318 >sp|O60318|MCM3A_HUMAN 80 kDa MCM3-associated protein OS=Homo sapiens GN=MCM3AP PE=1 SV=2 0.963282 17.199 0.963282 17.199 0.000261692 91.01 2.57271E-06 -55.8961 0.0732479 55.896 0 0 0 0 1 S PGDGEVSPSTEDA Proline-directed 0.05 0.000261692 91.01 _KPGDGEVpSPSTEDAPFQHSPLGK_ KPGDGEVS(0.963)PS(0.018)T(0.018)EDAPFQHSPLGK KPGDGEVS(17.2)PS(-17.2)T(-17.2)EDAPFQHS(-83.75)PLGK 8 3 820.70748 -0.64792 69321 69321 0 0 0 0 0 0 173 162 538 538 3148 3574 29920 18613 Mix4_TiO2_Reinj_1_1 4634 29919 18612 Mix4_TiO2_1_5 4887 O60318 O60318 O60318 >sp|O60318|MCM3A_HUMAN 80 kDa MCM3-associated protein OS=Homo sapiens GN=MCM3AP PE=1 SV=2 0.999992 55.8961 4.05926E-09 -83.7531 0.000261692 91.01 0.999992 55.8961 0.0732479 55.896 0 0 0 0 1 S DAPFQHSPLGKAA Proline-directed 0.05 0.000261692 91.01 _KPGDGEVSPSTEDAPFQHpSPLGK_ KPGDGEVSPSTEDAPFQHS(1)PLGK KPGDGEVS(-55.9)PS(-55.9)T(-55.9)EDAPFQHS(55.9)PLGK 19 3 820.70748 -0.02298 163650 0 0 0 163650 0 0 0 174 162 557 557 5988 6828 59144 35926 Mix4_TiO2_1_1 3249 59145 35927 Mix4_TiO2_Reinj_1_1 3760 O60318 O60318 O60318 >sp|O60318|MCM3A_HUMAN 80 kDa MCM3-associated protein OS=Homo sapiens GN=MCM3AP PE=1 SV=2 0.923859 15.2298 0.923859 15.2298 0.0558526 52.617 0.693828 3.57503 0.0258271 59.748 0 0 1 S SLLNKSSPVKKPS CDK1;CDK2;Polo box;Proline-directed 0.00405 0.0258271 59.748 _TGASSLLNKSpSPVK_ T(0.02)GAS(0.026)S(0.003)LLNKS(0.028)S(0.924)PVK T(-16.71)GAS(-15.51)S(-25.29)LLNKS(-15.23)S(15.23)PVK 11 2 734.87399 0.092024 224650 47185 0 0 177460 0 0 0 175 164 341 341 2557 2904 23958 14859 Mix4_TiO2_Reinj_1_5 2344 23958 14859 Mix4_TiO2_Reinj_1_5 2344 O60343;O60343-3;O60343-2 O60343 O60343 >sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4 PE=1 SV=2;>sp|O60343-3|TBCD4_HUMAN Isoform AS160_tv3 of TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4;>sp|O60343-2|TBCD4_HUMAN Isoform AS160_tv2 of TBC1 domain family memb 0.999823 37.5362 0.565301 5.91212 1.15333 5.9121 0.999823 37.5362 0.0160151 68.058 1 S PRRRHASAPSHVQ CAMK2;PIM1/2;PKA/AKT 0.000138852 0.0160151 68.058 _HApSAPSHVQPSDSEK_ HAS(1)APSHVQPSDSEK HAS(37.54)APS(-37.54)HVQPS(-68.06)DS(-68.06)EK 3 3 552.9053 0.088973 120220 12612 0 0 107610 0 0 0 176 164 588 588 3465 3911 32645 20237 Mix4_TiO2_1_5 4375 32645 20237 Mix4_TiO2_1_5 4375 O60343;O60343-3;O60343-2 O60343 O60343 >sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4 PE=1 SV=2;>sp|O60343-3|TBCD4_HUMAN Isoform AS160_tv3 of TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4;>sp|O60343-2|TBCD4_HUMAN Isoform AS160_tv2 of TBC1 domain family memb 0.999835 37.83 0.999835 37.83 0.067952 41.369 0.999813 37.288 0.120631 37.288 1 S MRGRLGSVDSFER CAMK2;PKA/AKT 0.001764 0.067952 41.369 _LGpSVDSFER_ LGS(1)VDSFER LGS(37.83)VDS(-37.83)FER 3 2 545.23425 0.41164 163080 40600 0 0 122470 0 0 0 177 164 569 569 5480 6236 53442 32640 Mix4_TiO2_1_5 7526 53442 32640 Mix4_TiO2_1_5 7526 O60343;O60343-3;O60343-2 O60343 O60343 >sp|O60343|TBCD4_HUMAN TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4 PE=1 SV=2;>sp|O60343-3|TBCD4_HUMAN Isoform AS160_tv3 of TBC1 domain family member 4 OS=Homo sapiens GN=TBC1D4;>sp|O60343-2|TBCD4_HUMAN Isoform AS160_tv2 of TBC1 domain family memb 0.564592 1.42209 0.564592 1.42209 0.0789499 42.751 0 0 1 S AKRSLTSSLENIF CK1;CK2 0.081 0.0789499 42.751 _SLTpSSLENIFSR_ S(0.001)LT(0.027)S(0.565)S(0.407)LENIFSR S(-25.96)LT(-13.2)S(1.42)S(-1.42)LENIFS(-42.75)R 4 2 717.33724 -0.052428 16113 16113 0 0 0 0 0 0 178 166 348 348 117 136 1225 783 Mix4_TiO2_Reinj_1_4 5616 1225 783 Mix4_TiO2_Reinj_1_4 5616 O60504;O60504-2 O60504 O60504 >sp|O60504|VINEX_HUMAN Vinexin OS=Homo sapiens GN=SORBS3 PE=1 SV=1;>sp|O60504-2|VINEX_HUMAN Isoform Beta of Vinexin OS=Homo sapiens GN=SORBS3 1 86.2158 0 0 1 86.2158 0.00111149 86.216 1 S KMADGGSPFLGRR Proline-directed 0.05 0.00111149 86.216 _(ac)ADGGpSPFLGR_ ADGGS(1)PFLGR ADGGS(86.22)PFLGR 5 2 549.73442 0.047446 52202 0 0 0 52202 0 0 0 179 168 480 480 4553 5171 43114 26444 Mix4_InSol_Tio2_Reinj_1 3716 43113 26443 Mix4_InSol_TiO2_1 3750 O60583;O60583-2 O60583 O60583 >sp|O60583|CCNT2_HUMAN Cyclin-T2 OS=Homo sapiens GN=CCNT2 PE=1 SV=2;>sp|O60583-2|CCNT2_HUMAN Isoform A of Cyclin-T2 OS=Homo sapiens GN=CCNT2 0.996451 24.769 0.996209 24.3279 2.70062E-06 112.98 0.994608 23.9908 9.97347E-07 116.23 0.80604 9.11324 6.66208E-09 119.21 0.996451 24.769 8.23056E-06 102.5 1 S SSSSVTSPIKMKI CDK1;CDK2;CK1;ERK/MAPK;Proline-directed 0.0034 6.66208E-09 119.21 _QGQSQAASSSSVTpSPIK_ QGQSQAASSSSVT(0.003)S(0.996)PIK QGQS(-102.5)QAAS(-67.7)S(-46.04)S(-39.36)S(-40.67)VT(-24.77)S(24.77)PIK 14 2 871.90146 0.15394 2961800 780180 0 0 1983900 0 129000 68740 180 170 281 281 4812 5462 45919 28082 Mix4_TiO2_Reinj_1_4 2131 45917 28079 Mix4_TiO2_1_2 2355 O60683-2;O60683 O60683-2 O60683-2 >sp|O60683-2|PEX10_HUMAN Isoform 2 of Peroxisome biogenesis factor 10 OS=Homo sapiens GN=PEX10;>sp|O60683|PEX10_HUMAN Peroxisome biogenesis factor 10 OS=Homo sapiens GN=PEX10 PE=1 SV=1 1 10.0772 1 32.6378 0.0901113 32.638 0 0 1 10.0772 0.344866 22.157 1 11.3589 0.748185 11.359 1 23.7624 0.330704 23.762 1 S LSHRRASLEERAV AURORA;AURORA-1;AURORA-A;CAMK2;CK2;PKA 0.004788 0.0901113 32.638 _RApSLEER_ RAS(1)LEER RAS(10.08)LEER 3 2 470.71603 0.38746 1403600 8912.7 0 0 973970 0 232430 188310 181 171 349 349 2449 2777 23017 14388 Mix4_TiO2_Reinj_1_3 6584 23017 14388 Mix4_TiO2_Reinj_1_3 6584 O60716;O60716-2;O60716-4;O60716-6;O60716-3;O60716-5;O60716-7;O60716-9;O60716-8;O60716-10;O60716-12;O60716-14;O60716-11;O60716-13;O60716-17;O60716-15;O60716-18;O60716-16;O60716-20;O60716-22;O60716-19;O60716-21;O60716-23;O60716-24;O60716-25;O60716-26;O60716-28;O60716-30;O60716-27;O60716-29;O60716-31;O60716-32 O60716 O60716 >sp|O60716|CTND1_HUMAN Catenin delta-1 OS=Homo sapiens GN=CTNND1 PE=1 SV=1;>sp|O60716-2|CTND1_HUMAN Isoform 1AB of Catenin delta-1 OS=Homo sapiens GN=CTNND1;>sp|O60716-4|CTND1_HUMAN Isoform 1BC of Catenin delta-1 OS=Homo sapiens GN=CTNND1;>sp|O60716-6|CTND 0.996858 25.0269 0 0 0.996858 25.0269 0.0369507 50.322 1 S ERGSLASLDSLRK CK1 0.081 0.0369507 50.322 _GSLApSLDSLR_ GSLAS(0.997)LDS(0.003)LR GS(-50.32)LAS(25.03)LDS(-25.03)LR 5 2 549.76318 0.34964 29278 0 0 0 29278 0 0 0 182 172 7 7 505;506 571;572 4707 2845 Mix4_TiO2_1_6 2804 4681 2836 Mix4_TiO2_Reinj_1_6 3669 O60762 O60762 O60762 >sp|O60762|DPM1_HUMAN Dolichol-phosphate mannosyltransferase OS=Homo sapiens GN=DPM1 PE=1 SV=1 0.910106 10.0536 0.910106 10.0536 0.00419093 76.71 0.597434 1.72488 0.227861 27.946 0.61608 2.05399 0.00339994 107.83 0 0 0.374515 -2.22748 0.00290459 81.134 0.632796 2.36358 0.0106787 60.749 1 S MASLEVSRSPRRS CK1;NEK6 0.076 0.00339994 107.83 _(ac)ASLEVpSRSPRR_ ASLEVS(0.91)RS(0.09)PRR AS(-65.08)LEVS(10.05)RS(-10.05)PRR 6 3 460.56455 -0.4283 2178600 577360 50279 0 719880 0 0 831120 183 172 9 9 505;506 571;572 4709 2847 Mix4_TiO2_Reinj_1_2 3364 4681 2836 Mix4_TiO2_Reinj_1_6 3669 O60762 O60762 O60762 >sp|O60762|DPM1_HUMAN Dolichol-phosphate mannosyltransferase OS=Homo sapiens GN=DPM1 PE=1 SV=1 0.997316 25.7003 0.948588 12.6633 0.00419093 76.71 0.747678 4.76765 0.227861 27.946 0.997316 25.7003 0.00339994 107.83 0 0 0.939597 13.9491 0.00290459 81.134 0.949364 12.7318 0.0106787 60.749 1 S SLEVSRSPRRSRR CDK1;CDK2;GSK3;Proline-directed 0.0057 0.00339994 107.83 _(ac)ASLEVSRpSPRR_ ASLEVS(0.003)RS(0.997)PRR AS(-64.46)LEVS(-25.7)RS(25.7)PRR 8 3 460.56455 -0.3483 13859000 2179800 534300 0 7912000 0 2579400 653940 184 173 953 953 988;3494 1112;3946 32993 20430 Mix4_TiO2_Reinj_1_5 6146 32993 20430 Mix4_TiO2_Reinj_1_5 6146 O60763-2;O60763 O60763-2 O60763-2 >sp|O60763-2|USO1_HUMAN Isoform 2 of General vesicular transport factor p115 OS=Homo sapiens GN=USO1;>sp|O60763|USO1_HUMAN General vesicular transport factor p115 OS=Homo sapiens GN=USO1 PE=1 SV=2 0.999998 57.6301 0.999787 36.7107 0.00049247 80.12 0 0 0.999998 57.6301 1.76091E-07 114.84 0 0 0 0 1 S EEDELESGDQEDE 1.76091E-07 114.84 _LKDLGHPVEEEDELEpSGDQEDEDDESEDPGKDLDHI_ LKDLGHPVEEEDELES(1)GDQEDEDDESEDPGKDLDHI LKDLGHPVEEEDELES(57.63)GDQEDEDDES(-57.63)EDPGKDLDHI 16 4 1040.1802 -0.33179 9334700 1.2315 1158900 0 0 8175700 0 0 0 185 175 214 214 4103 4672 38838 23822 Mix4_InSol_Tio2_Reinj_1 4728 38838 23822 Mix4_InSol_Tio2_Reinj_1 4728 O60841 O60841 O60841 >sp|O60841|IF2P_HUMAN Eukaryotic translation initiation factor 5B OS=Homo sapiens GN=EIF5B PE=1 SV=4 1 99.3774 0 0 0.497476 -0.0438413 1.39653 8.3979 1 69.6229 7.78336E-05 97.57 1 99.3774 4.2144E-06 99.377 1 S PGPNIESGNEDDD CK2 0.117 4.2144E-06 99.377 _NKPGPNIEpSGNEDDDASFK_ NKPGPNIES(1)GNEDDDASFK NKPGPNIES(99.38)GNEDDDAS(-99.38)FK 9 2 1057.4391 0.2733 80885 0 0 0 0 0 37131 43753 186 175 222 222 4103 4672 38839 23823 Mix4_TiO2_Reinj_1_5 4481 38838 23822 Mix4_InSol_Tio2_Reinj_1 4728 O60841 O60841 O60841 >sp|O60841|IF2P_HUMAN Eukaryotic translation initiation factor 5B OS=Homo sapiens GN=EIF5B PE=1 SV=4 0.502524 0.0438413 0 0 0.502524 0.0438413 1.39653 8.3979 1.0907E-07 -69.6229 7.78336E-05 97.57 1.15413E-10 -99.3774 4.2144E-06 99.377 1 S NEDDDASFKIKTV PLK1 0.033462 4.2144E-06 99.377 _NKPGPNIESGNEDDDApSFK_ NKPGPNIES(0.497)GNEDDDAS(0.503)FK NKPGPNIES(-0.04)GNEDDDAS(0.04)FK 17 3 705.29518 -0.31257 75469 0 0 0 75469 0 0 0 187 176 1361 1361 3156 3583 29969 18635 Mix4_InSol_Tio2_Reinj_1 4946 29969 18635 Mix4_InSol_Tio2_Reinj_1 4946 O75116 O75116 O75116 >sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 OS=Homo sapiens GN=ROCK2 PE=1 SV=4 0.649105 2.67137 0.5 0 0.88748 9.8441 0.649105 2.67137 0.0700453 49.246 1 S PDPFARSSPRTSM 0.0700453 49.246 _KPPAPDPFARpSSPR_ KPPAPDPFARS(0.649)S(0.351)PR KPPAPDPFARS(2.67)S(-2.67)PR 11 2 801.89305 -0.47614 591440 0 0 0 0 0 271930 319510 188 176 1362 1362 3156 3583 29968 18634 Mix4_InSol_Tio2_Reinj_1 4931 29969 18635 Mix4_InSol_Tio2_Reinj_1 4946 O75116 O75116 O75116 >sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 OS=Homo sapiens GN=ROCK2 PE=1 SV=4 0.5 0 0.5 0 0.88748 9.8441 0.5 0 0.0700453 49.246 1 S DPFARSSPRTSMK CDK1;GSK3;PKA;Polo box;Proline-directed 0.00405 0.0700453 49.246 _KPPAPDPFARpSSPR_ KPPAPDPFARS(0.5)S(0.5)PR KPPAPDPFARS(0)S(0)PR 12 3 534.93112 -0.015882 511100 0 0 0 0 0 271930 239170 189 177 368 368 5677 6465 55636 34093 Mix4_InSol_Tio2_Reinj_1 3779 55638 34095 Mix4_TiO2_Reinj_1_5 3526 O75122;O75122-2 O75122 O75122 >sp|O75122|CLAP2_HUMAN CLIP-associating protein 2 OS=Homo sapiens GN=CLASP2 PE=1 SV=2;>sp|O75122-2|CLAP2_HUMAN Isoform CLASP2 beta of CLIP-associating protein 2 OS=Homo sapiens GN=CLASP2 0.657003 2.82276 0.636475 2.43248 0.000196876 101.2 0.123721 -8.50201 1.71963E-06 119.4 0.125643 -8.4255 9.95682E-05 109.62 0.657003 2.82276 0.00138873 91.772 1 S PGSLQRSRSDIDV CK1;CK2;NEK6 0.076 1.71963E-06 119.4 _pSRSDIDVNAAAGAK_ S(0.657)RS(0.343)DIDVNAAAGAK S(2.82)RS(-2.82)DIDVNAAAGAK 1 2 727.83539 0.58708 223150 108310 0 0 0 0 0 114830 190 177 370 370 5677 6465 55638 34095 Mix4_TiO2_Reinj_1_5 3526 55638 34095 Mix4_TiO2_Reinj_1_5 3526 O75122;O75122-2 O75122 O75122 >sp|O75122|CLAP2_HUMAN CLIP-associating protein 2 OS=Homo sapiens GN=CLASP2 PE=1 SV=2;>sp|O75122-2|CLAP2_HUMAN Isoform CLASP2 beta of CLIP-associating protein 2 OS=Homo sapiens GN=CLASP2 0.876279 8.50201 0.363525 -2.43248 0.000196876 101.2 0.876279 8.50201 1.71963E-06 119.4 0.874357 8.4255 9.95682E-05 109.62 0.342997 -2.82276 0.00138873 91.772 1 S SLQRSRSDIDVNA CAMK2;CHK1;CHK1/2;CK2;PKD 0.003192 1.71963E-06 119.4 _SRpSDIDVNAAAGAK_ S(0.124)RS(0.876)DIDVNAAAGAK S(-8.5)RS(8.5)DIDVNAAAGAK 3 2 727.83539 0.12273 460370 0 0 0 368340 0 92031 0 191 177 596 596 6482 7415 65464 40130 Mix4_TiO2_Reinj_1_5 8456 65464 40130 Mix4_TiO2_Reinj_1_5 8456 O75122 O75122 O75122 >sp|O75122|CLAP2_HUMAN CLIP-associating protein 2 OS=Homo sapiens GN=CLASP2 PE=1 SV=2 0.5 0 0 0 0.5 0 0.0124034 70.623 1 S RVLNTGSDVEEAV CK2 0.117 0.0124034 70.623 _VLNpTGSDVEEAVADALK_ VLNT(0.5)GS(0.5)DVEEAVADALK VLNT(0)GS(0)DVEEAVADALK 6 3 604.28719 -0.50384 22304 0 0 0 22304 0 0 0 192 179 664 664 5200 5921 50412 30905 Mix4_TiO2_1_5 3153 50412 30905 Mix4_TiO2_1_5 3153 O75153 O75153 O75153 >sp|O75153|K0664_HUMAN Protein KIAA0664 OS=Homo sapiens GN=KIAA0664 PE=1 SV=2 0.99999 50.854 0.99999 50.854 2.73377E-11 122.91 0.999645 34.5955 2.95617E-11 121.74 1 S PGQEAGSEEEGSS CK2 0.117 2.73377E-11 122.91 _SEDPPGQEAGpSEEEGSSASGLAK_ SEDPPGQEAGS(1)EEEGSSASGLAK S(-63.03)EDPPGQEAGS(50.85)EEEGS(-50.85)S(-58.43)AS(-91.02)GLAK 11 2 1149.9659 0.89271 141560 0.14106 46067 0 0 95492 0 0 0 193 181 770 770 690 792 6672 3957 Mix4_InSol_Tio2_Reinj_1 2861 6672 3957 Mix4_InSol_Tio2_Reinj_1 2861 O75170;O75170-5;O75170-3;O75170-4;O75170-2;O75170-6 O75170 O75170 >sp|O75170|PP6R2_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens GN=PPP6R2 PE=1 SV=2;>sp|O75170-5|PP6R2_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens GN=PPP6R2;>sp|O75170-3| 0.499997 0 0.499996 0 0.0684421 53.612 0.499997 0 0.0564365 55.457 1 S ESGPRCSSPVDTE PKA 0.042 0.0564365 55.457 _CpSSPVDTECSHAEGSR_ CS(0.5)S(0.5)PVDTECSHAEGSR CS(0)S(0)PVDT(-52.07)ECS(-55.46)HAEGS(-55.46)R 2 2 929.84022 0.13063 113430 0 0 0 0 0 66862 46567 194 181 771 771 690 792 6669 3954 Mix4_InSol_TiO2_1 2843 6672 3957 Mix4_InSol_Tio2_Reinj_1 2861 O75170;O75170-5;O75170-3;O75170-4;O75170-2;O75170-6 O75170 O75170 >sp|O75170|PP6R2_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens GN=PPP6R2 PE=1 SV=2;>sp|O75170-5|PP6R2_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens GN=PPP6R2;>sp|O75170-3| 0.998602 29.2129 0.998602 29.2129 0.0684421 53.612 0.997798 28.335 0.0564365 55.457 1 S SGPRCSSPVDTEC CAMK2;CK2;Polo box;Proline-directed 0.00405 0.0564365 55.457 _CSpSPVDTECSHAEGSR_ CS(0.001)S(0.999)PVDTECSHAEGSR CS(-29.21)S(29.21)PVDT(-37.16)ECS(-53.61)HAEGS(-53.61)R 3 3 620.22924 -0.27208 238020 0 0 0 0 0 138540 99483 195 182 506 506 1729 1946 15879 9613 Mix4_TiO2_1_5 7247 15880 9614 Mix4_TiO2_Reinj_1_5 7893 O75175;O75175-2;O75175-3 O75175 O75175 >sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3 PE=1 SV=1;>sp|O75175-2|CNOT3_HUMAN Isoform 2 of CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3;>sp|O75175-3|CNOT3_HUMAN Isoform 3 of CCR4-NOT transc 0.348585 0 0.348585 0 0.0816137 77.496 0.286279 0 0.00592881 90.374 1 S LPVNPPSSPTPSF 0.00592881 90.374 _EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPpSSPTPSFSDAK_ EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPS(0.349)S(0.349)PT(0.125)PS(0.136)FS(0.042)DAK EPS(-48.33)AAAPT(-48.39)GAGGVAPGS(-34.17)GNNS(-34.17)GGPS(-34.17)LLVPLPVNPPS(0)S(0)PT(-4.47)PS(-4.1)FS(-9.16)DAK 36 4 1073.5193 -1.6109 0 0 0 0 0 0 0 0 0 196 182 507 507 1729 1946 15879 9613 Mix4_TiO2_1_5 7247 15880 9614 Mix4_TiO2_Reinj_1_5 7893 O75175;O75175-2;O75175-3 O75175 O75175 >sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3 PE=1 SV=1;>sp|O75175-2|CNOT3_HUMAN Isoform 2 of CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3;>sp|O75175-3|CNOT3_HUMAN Isoform 3 of CCR4-NOT transc 0.348585 0 0.348585 0 0.0816137 77.496 0.286279 0 0.00592881 90.374 1 S PVNPPSSPTPSFS ERK/MAPK;GSK3;Polo box;Proline-directed;WW GroupIV 0.0023175 0.00592881 90.374 _EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPpSSPTPSFSDAK_ EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPS(0.349)S(0.349)PT(0.125)PS(0.136)FS(0.042)DAK EPS(-48.33)AAAPT(-48.39)GAGGVAPGS(-34.17)GNNS(-34.17)GGPS(-34.17)LLVPLPVNPPS(0)S(0)PT(-4.47)PS(-4.1)FS(-9.16)DAK 37 4 1073.5193 -1.6109 0 0 0 0 0 0 0 0 0 197 182 299 299 5773 6578 56851 34680 Mix4_TiO2_Reinj_1_5 1997 56851 34680 Mix4_TiO2_Reinj_1_5 1997 O75175;O75175-2;O75175-3 O75175 O75175 >sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3 PE=1 SV=1;>sp|O75175-2|CNOT3_HUMAN Isoform 2 of CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3;>sp|O75175-3|CNOT3_HUMAN Isoform 3 of CCR4-NOT transc 0.999278 31.4091 0.982748 17.556 0.00254977 93.764 0.999278 31.4091 0.00114093 98.902 0.997662 26.3015 0.00633879 80.167 0.971828 15.3777 0.00888397 75.248 1 S DSEVSQSPAKNGS CDK1;CDK2;Proline-directed 0.0057 0.00114093 98.902 _STDSEVSQpSPAK_ STDSEVS(0.001)QS(0.999)PAK S(-98.9)T(-98.9)DS(-79.36)EVS(-31.41)QS(31.41)PAK 9 2 658.2743 0.49807 592510 84590 0 0 409330 0 56694 41895 198 183 1003 1003 6819 7803 69136 42384 Mix4_TiO2_Reinj_1_5 8645 69136 42384 Mix4_TiO2_Reinj_1_5 8645 O75182;O75182-2 O75182 O75182 >sp|O75182|SIN3B_HUMAN Paired amphipathic helix protein Sin3b OS=Homo sapiens GN=SIN3B PE=1 SV=2;>sp|O75182-2|SIN3B_HUMAN Isoform 2 of Paired amphipathic helix protein Sin3b OS=Homo sapiens GN=SIN3B 0.753238 8.72965 0 0 0.753238 8.72965 0.000247656 82.341 1 S TEGASSSPTEGFL CK2;Polo box;Proline-directed 0.00405 0.000247656 82.341 _YVEQYVGTEGASSpSPTEGFLLKPVFLQR_ YVEQYVGT(0.009)EGAS(0.068)S(0.068)S(0.753)PT(0.101)EGFLLKPVFLQR Y(-74.81)VEQY(-42.31)VGT(-19.3)EGAS(-10.41)S(-10.41)S(8.73)PT(-8.73)EGFLLKPVFLQR 14 3 1061.5197 0.11894 177980 0 0 0 177980 0 0 0 199 184 277 277 2556 2902 23937 14856 Mix4_TiO2_Reinj_1_4 3316 23937 14856 Mix4_TiO2_Reinj_1_4 3316 O75190;O75190-3 O75190 O75190 >sp|O75190|DNJB6_HUMAN DnaJ homolog subfamily B member 6 OS=Homo sapiens GN=DNAJB6 PE=1 SV=2;>sp|O75190-3|DNJB6_HUMAN Isoform a of DnaJ homolog subfamily B member 6 OS=Homo sapiens GN=DNAJB6 1 124.315 1 23.8921 0.685456 23.892 0 0 1 124.315 4.78862E-09 124.32 1 0.284201 0.0144392 68.902 1 73.4113 9.50359E-06 100.11 1 S HAPHCLSEEEGEQ CK2 0.117 4.78862E-09 124.32 _HAPHCLpSEEEGEQDRPR_ HAPHCLS(1)EEEGEQDRPR HAPHCLS(124.32)EEEGEQDRPR 7 2 1063.9391 0.39965 7092000 92.331 88203 0 0 4504900 0 1388900 1110000 200 187 450 450 4156 4732 39607 24447 Mix4_TiO2_Reinj_1_5 4992 39607 24447 Mix4_TiO2_Reinj_1_5 4992 O75385 O75385 O75385 >sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo sapiens GN=ULK1 PE=1 SV=1 0.999621 34.2141 0.974517 15.8254 3.68188E-10 98.112 0.999621 34.2141 0.00057102 109.7 0.675742 3.18889 0.00115889 98.756 0.986693 18.701 0.00621044 80.627 1 S IERNLQSPTQFQT Proline-directed 0.05 0.00057102 109.7 _NLQpSPTQFQTPR_ NLQS(1)PTQFQTPR NLQS(34.21)PT(-34.21)QFQT(-74.17)PR 4 2 748.8483 -0.72368 232370 0 0 0 132970 0 66066 33332 201 187 638 638 6159 7031 60998 36969 Mix4_TiO2_Reinj_1_5 8568 60998 36969 Mix4_TiO2_Reinj_1_5 8568 O75385 O75385 O75385 >sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo sapiens GN=ULK1 PE=1 SV=1 0.821641 8.69281 0.275166 -2.13298 0.0164943 65.544 0 0 0.821641 8.69281 5.05836E-06 139.07 1 S DFPKTPSSQNLLA 5.05836E-06 139.07 _TPpSSQNLLALLAR_ T(0.067)PS(0.822)S(0.111)QNLLALLAR T(-10.86)PS(8.69)S(-8.69)QNLLALLAR 3 2 732.38452 0.023148 110160 0 0 0 110160 0 0 0 202 187 639 639 6159 7031 60995 36965 Mix4_TiO2_1_1 7362 60998 36969 Mix4_TiO2_Reinj_1_5 8568 O75385 O75385 O75385 >sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 OS=Homo sapiens GN=ULK1 PE=1 SV=1 0.842709 7.98162 0.842709 7.98162 0.0164943 65.544 0 0 0.411248 1.45201 5.05836E-06 139.07 1 S FPKTPSSQNLLAL 5.05836E-06 139.07 _TPSpSQNLLALLAR_ T(0.023)PS(0.134)S(0.843)QNLLALLAR T(-15.61)PS(-7.98)S(7.98)QNLLALLAR 4 2 732.38452 -0.37079 7463.3 7463.3 0 0 0 0 0 0 203 191 25 25 22 30 248 145 Mix4_TiO2_1_3 6617 248 145 Mix4_TiO2_1_3 6617 O75427 O75427 O75427 >sp|O75427|LRCH4_HUMAN Leucine-rich repeat and calponin homology domain-containing protein 4 OS=Homo sapiens GN=LRCH4 PE=1 SV=2 0.995975 25.2135 0.995975 25.2135 0.0328101 65.078 0 0 1 S TTSVPGSPGLPGR CK1;ERK/MAPK;Proline-directed 0.0025 0.0328101 65.078 _(ac)AAAVAAPLAAGGEEAAATTSVPGpSPGLPGR_ AAAVAAPLAAGGEEAAATT(0.001)S(0.003)VPGS(0.996)PGLPGR AAAVAAPLAAGGEEAAAT(-36.49)T(-30.93)S(-25.21)VPGS(25.21)PGLPGR 24 3 913.78316 0.30856 119750 119750 0 0 0 0 0 0 204 194 131 131 3044 3462;3463 29076 18181 Mix4_TiO2_Reinj_1_6 7248 29076 18181 Mix4_TiO2_Reinj_1_6 7248 O75446 O75446 O75446 >sp|O75446|SAP30_HUMAN Histone deacetylase complex subunit SAP30 OS=Homo sapiens GN=SAP30 PE=1 SV=1 0.996978 25.1843 0 0 0.996978 25.1843 1.39008E-36 178.83 1 S RRKRKGSDDDGGD CAMK2;CK2;PKA;PKA/AKT 0.001764 1.39008E-36 178.83 _KGpSDDDGGDSPVQDIDTPEVDLYQLQVNTLR_ KGS(0.997)DDDGGDS(0.003)PVQDIDTPEVDLYQLQVNTLR KGS(25.18)DDDGGDS(-25.18)PVQDIDT(-107.69)PEVDLY(-151.56)QLQVNT(-178.83)LR 3 3 1157.1929 0.18958 121780 0 0 0 121780 0 0 0 205 194 138 138 3044 3462;3463 29078 18182 Mix4_TiO2_Reinj_1_6 7275 29078 18182 Mix4_TiO2_Reinj_1_6 7275 O75446 O75446 O75446 >sp|O75446|SAP30_HUMAN Histone deacetylase complex subunit SAP30 OS=Homo sapiens GN=SAP30 PE=1 SV=1 0.999941 42.2682 0 0 0.999941 42.2682 1.04793E-12 125.14 2 S DDDGGDSPVQDID Proline-directed 0.05 1.04793E-12 125.14 _KGpSDDDGGDpSPVQDIDTPEVDLYQLQVNTLR_ KGS(1)DDDGGDS(1)PVQDIDTPEVDLYQLQVNTLR KGS(48.97)DDDGGDS(42.27)PVQDIDT(-42.27)PEVDLY(-93.41)QLQVNT(-116.56)LR 10 3 1183.8484 -0.092872 94786 0 0 0 94786 0 0 0 206 195 862 862 3582 4038 33734 20787 Mix4_TiO2_1_3 5850 33733 20786 Mix4_TiO2_1_3 5077 O75448 O75448 O75448 >sp|O75448|MED24_HUMAN Mediator of RNA polymerase II transcription subunit 24 OS=Homo sapiens GN=MED24 PE=1 SV=1 0.997346 25.7489 0.997346 25.7489 3.10574E-31 199.03 0.976192 16.1282 8.95084E-26 182.56 6.97499E-16 -148.963 1.35768E-15 148.96 0.000227313 -35.5251 3.2122E-06 109.1 1 S KLMRLLSSNEDDA CAMK2;CHK1;CHK1/2;CK2;PKD 0.003192 3.10574E-31 199.03 _LLpSSNEDDANILSSPTDR_ LLS(0.997)S(0.003)NEDDANILSSPTDR LLS(25.75)S(-25.75)NEDDANILS(-115.8)S(-140.77)PT(-146.57)DR 3 2 1013.9519 -0.38332 659500 203770 0 0 455740 0 0 0 207 195 873 873 3582 4038 33731 20784 Mix4_InSol_Tio2_Reinj_1 6160 33733 20786 Mix4_TiO2_1_3 5077 O75448 O75448 O75448 >sp|O75448|MED24_HUMAN Mediator of RNA polymerase II transcription subunit 24 OS=Homo sapiens GN=MED24 PE=1 SV=1 0.987527 21.6269 0.937322 13.6785 3.10574E-31 199.03 0.927539 11.1056 8.95084E-26 182.56 0.549362 0.868444 1.35768E-15 148.96 0.987527 21.6269 3.2122E-06 109.1 1 S DANILSSPTDRSM CK2;Polo box;Proline-directed 0.00405 3.10574E-31 199.03 _LLSSNEDDANILSpSPTDR_ LLSSNEDDANILS(0.006)S(0.988)PT(0.007)DR LLS(-109.1)S(-109.1)NEDDANILS(-22.4)S(21.63)PT(-21.63)DR 14 2 1013.9519 0.25628 2136200 495870 0 0 1053400 0 331000 255910 208 199 242 242 300;2432 341;342;2756;2757 2806 1729 Mix4_TiO2_Reinj_1_5 1655 2805 1727 Mix4_TiO2_Reinj_1_5 1650 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.993434 23.7341 0.258028 -8.21295 0.942316 8.2129 0.466824 0 0.557737 11.483 0.993434 23.7341 0.00118782 92.985 0.839001 7.32367 0.296738 23.826 0.586835 3.54303 0.225907 34.893 1 S PGRAKGSETPGAT 0.00118782 92.985 _AKGpSETPGATPGSK_ AKGS(0.993)ET(0.004)PGAT(0.001)PGS(0.001)K AKGS(23.73)ET(-23.73)PGAT(-29.25)PGS(-29.25)K 4 3 456.54493 -0.037679 38622 0 0 0 38622 0 0 0 209 199 216 216 3125;3748 3549;3550;4228 29749 18529 Mix4_InSol_Tio2_Reinj_1 5774 35449 21897 Mix4_TiO2_Reinj_1_5 5570 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.261954 0 0.18895 -4.94349 0.529956 30.088 0 0 0.000118003 -38.4602 0.111353 47.629 0 0 0.261954 0 1.47911 2.1765 1 S ATPKKLSSWDQAE CK2 0.117 0.111353 47.629 _KLpSSWDQAETPGHTPSLR_ KLS(0.262)S(0.262)WDQAET(0.159)PGHT(0.159)PS(0.159)LR KLS(0)S(0)WDQAET(-2.18)PGHT(-2.18)PS(-2.18)LR 3 3 697.32827 0.90541 0 0 0 0 0 0 0 0 210 199 217 217 3125;3748 3549;3550;4228 29749 18529 Mix4_InSol_Tio2_Reinj_1 5774 35449 21897 Mix4_TiO2_Reinj_1_5 5570 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.261954 0 0.18895 -4.94349 0.529956 30.088 0 0 0.000118003 -38.4602 0.111353 47.629 0 0 0.261954 0 1.47911 2.1765 1 S TPKKLSSWDQAET 0.111353 47.629 _KLpSSWDQAETPGHTPSLR_ KLS(0.262)S(0.262)WDQAET(0.159)PGHT(0.159)PS(0.159)LR KLS(0)S(0)WDQAET(-2.18)PGHT(-2.18)PS(-2.18)LR 4 3 697.32827 0.90541 0 0 0 0 0 0 0 0 211 199 129 129 6103 6966 60311 36503 Mix4_TiO2_Reinj_1_5 7738 60311 36503 Mix4_TiO2_Reinj_1_5 7738 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.999973 45.6703 0 0 0.999973 45.6703 0.124821 45.67 1 S RRTMIISPERLDP CDK1;CDK2;CK1;Proline-directed 0.0057 0.124821 45.67 _TM(ox)IIpSPERLDPFADGGK_ TMIIS(1)PERLDPFADGGK T(-45.67)MIIS(45.67)PERLDPFADGGK 5 3 648.30419 -0.070774 91124 0 0 0 91124 0 0 0 212 201 2831 2831 5399 6145 52594 32160 Mix4_TiO2_1_1 4442 52594 32160 Mix4_TiO2_1_1 4442 O75592;O75592-2 O75592 O75592 >sp|O75592|MYCB2_HUMAN Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 PE=1 SV=3;>sp|O75592-2|MYCB2_HUMAN Isoform 2 of Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 0.990233 20.0739 0.990233 20.0739 0.0020959 87.501 0 0 0 0 0 0 0 0 1 S DPPRERSKSDSYT CAMK2;CK2;GSK3 0.042 0.0020959 87.501 _pSKSDSYTLDPDTLR_ S(0.99)KS(0.01)DSYTLDPDTLR S(20.07)KS(-20.07)DS(-45.1)Y(-60.77)T(-61.68)LDPDT(-87.5)LR 1 2 839.37201 0.55582 36578 36578 0 0 0 0 0 0 213 201 3467 3467 6514 7453 65832 40331 Mix4_TiO2_Reinj_1_1 5345 65832 40331 Mix4_TiO2_Reinj_1_1 5345 O75592;O75592-2 O75592 O75592 >sp|O75592|MYCB2_HUMAN Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 PE=1 SV=3;>sp|O75592-2|MYCB2_HUMAN Isoform 2 of Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 0.999998 56.4509 0.999973 45.7041 8.70247E-05 110.73 0.999998 56.4509 9.46213E-07 127.54 0 0 0 0 1 S PRRRVNSGDTEVG CAMK2;PKA/AKT 0.001764 9.46213E-07 127.54 _VNpSGDTEVGSSLLR_ VNS(1)GDTEVGSSLLR VNS(56.45)GDT(-56.45)EVGS(-115.98)S(-127.53)LLR 3 2 757.34833 -0.208 277150 38553 0 0 238600 0 0 0 214 202 225 225 1471 1653;1654 13715 8376 Mix4_TiO2_Reinj_1_1 4076 13715 8376 Mix4_TiO2_Reinj_1_1 4076 O75643;O75643-2 O75643 O75643 >sp|O75643|U520_HUMAN U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens GN=SNRNP200 PE=1 SV=2;>sp|O75643-2|U520_HUMAN Isoform 2 of U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens GN=SNRNP200 1 200.089 1 147.077 1.87784E-12 147.08 1 200.089 1.02008E-25 200.09 1 S EVREEASDDDMEG CK2 0.117 1.02008E-25 200.09 _EEApSDDDMEGDEAVVR_ EEAS(1)DDDMEGDEAVVR EEAS(200.09)DDDMEGDEAVVR 4 2 923.83787 -0.14161 636090 92836 0 0 543250 0 0 0 215 203 634 634 1557 1748 14233 8660 Mix4_TiO2_Reinj_1_3 6993 14233 8660 Mix4_TiO2_Reinj_1_3 6993 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 1 111.63 0 0 1 111.63 1.45251E-06 111.63 1 S IREGRFSLDGEAW AURORA;AURORA-1;PKA 0.020748 1.45251E-06 111.63 _EGRFpSLDGEAWQGVSEEAK_ EGRFS(1)LDGEAWQGVSEEAK EGRFS(111.63)LDGEAWQGVS(-111.63)EEAK 5 3 725.65119 0.0084372 441650 0 0 0 441650 0 0 0 216 203 343 343 3399 3840;3841 32022 19799 Mix4_TiO2_Reinj_1_3 5212 32022 19799 Mix4_TiO2_Reinj_1_3 5212 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 0.999988 49.3948 0.999882 39.2962 8.61937E-06 101.76 0.210238 -5.7445 0.00887376 73.671 0.999988 49.3948 2.34547E-06 113.65 0.00342804 -24.6344 0.00144296 85.077 0.409636 -0.159739 1.53265E-12 139.32 2 S RLEPVYSPPGSPP ERK/MAPK;GSK3;Proline-directed 0.0034 2.34547E-06 113.65 _LEPVYpSPPGpSPPPGDPR_ LEPVYS(1)PPGS(1)PPPGDPR LEPVY(-49.39)S(49.39)PPGS(64.29)PPPGDPR 6 2 961.41028 0.27733 1020600 191600 0 0 829000 0 0 0 217 203 347 347 3399 3840;3841 31995 19779 Mix4_InSol_Tio2_Reinj_1 5503 32003 19793 Mix4_TiO2_Reinj_1_3 5240 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 0.999985 48.2348 0.998382 27.9026 2.69741E-09 130.02 0.963917 14.2757 0.00887376 73.671 0.999978 46.6021 1.38089E-12 141.01 0.999296 31.5299 0.00144296 85.077 0.999985 48.2348 1.53265E-12 139.32 1 S VYSPPGSPPPGDP CK1;ERK/MAPK;Proline-directed 0.0025 1.38089E-12 141.01 _LEPVYSPPGpSPPPGDPR_ LEPVYSPPGS(1)PPPGDPR LEPVY(-86.98)S(-48.23)PPGS(48.23)PPPGDPR 10 2 921.42712 0.039929 4926000 1203500 127640 0 3245100 0 195170 154650 218 203 745 745 4894 5565 46999 28750 Mix4_TiO2_Reinj_1_3 1666 46998 28748 Mix4_TiO2_Reinj_1_3 1629 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 1 21.0634 0 0 0 0 1 21.0634 0.00721438 69.272 1 2.83977 0.0105388 61.094 1 45.314 0.0611983 45.314 1 S TASRRGSPAPANP CAMK2;CK1;PKA;Proline-directed 0.004788 0.00721438 69.272 _RGpSPAPANPGR_ RGS(1)PAPANPGR RGS(21.06)PAPANPGR 3 3 387.18378 0.14313 3028900 0 0 0 2577600 0 263830 187440 219 203 681 681 5724 6523;6524 56226 34380 Mix4_TiO2_1_3 5238 56226 34380 Mix4_TiO2_1_3 5238 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 0.504346 0 0.504346 0 2.99461E-06 104.8 0 0 0.489024 -0.194057 0.00101638 81.539 0.440448 -0.95003 0.0459289 57.106 0.348857 0 0.412676 34.864 2 S QDGSARSSPPLRT CK1 0.081 2.99461E-06 104.8 _pSSPPLRpTPDVLESSGPAVR_ S(0.504)S(0.504)PPLRT(0.991)PDVLESSGPAVR S(0)S(0)PPLRT(17.56)PDVLES(-92.2)S(-104.78)GPAVR 1 3 708.99573 0.24252 171230 171230 0 0 0 0 0 0 220 203 682 682 5724 6523;6524 56196 34361 Mix4_InSol_TiO2_1 6612 56204 34377 Mix4_TiO2_Reinj_1_3 6206 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 0.548148 0.95003 0.504346 0 2.99461E-06 104.8 0 0 0.511353 0.194057 0.00101638 81.539 0.548148 0.95003 0.0459289 57.106 0.348857 0 0.412676 34.864 1 S DGSARSSPPLRTP CK1;PKA;Polo box;Proline-directed 0.00405 0.00667054 74.025 _SpSPPLRTPDVLESSGPAVR_ S(0.44)S(0.548)PPLRT(0.011)PDVLESSGPAVR S(-0.95)S(0.95)PPLRT(-16.82)PDVLES(-57.11)S(-57.11)GPAVR 2 3 682.34029 -0.27343 1502100 0 0 0 0 0 1502100 0 221 205 2601 2601 184;185 213;214 1934 1296 Mix4_TiO2_Reinj_1_1 3988 1933 1295 Mix4_TiO2_Reinj_1_1 3968 O75691 O75691 O75691 >sp|O75691|UTP20_HUMAN Small subunit processome component 20 homolog OS=Homo sapiens GN=UTP20 PE=1 SV=3 1 58.0045 1 79.0844 0.0061969 80.676 0 0 1 58.0045 8.01388E-10 135.21 0 0 1 S ADEKAESDGEEKE CK2 0.117 8.01388E-10 135.21 _AEpSDGEEKEEVKEELGR_ AES(1)DGEEKEEVKEELGR AES(58)DGEEKEEVKEELGR 3 3 671.9598 0.29523 2154700 425920 0 0 1728700 0 0 0 222 205 788 788 5823 6640 57430 34967 Mix4_TiO2_Reinj_1_1 7034 57430 34967 Mix4_TiO2_Reinj_1_1 7034 O75691 O75691 O75691 >sp|O75691|UTP20_HUMAN Small subunit processome component 20 homolog OS=Homo sapiens GN=UTP20 PE=1 SV=3 0.998997 30.8464 0.99452 23.5783 1.05788E-11 121.57 0.981175 17.3752 0.110029 56.899 0.998997 30.8464 9.75988E-19 154.67 0 0 0.773497 8.51813 1.94111 14.518 1 S KSVGDESWEQTQE PLK1 0.033462 9.75988E-19 154.67 _SVGDEpSWEQTQEGDVGALYHEQLALK_ S(0.001)VGDES(0.999)WEQTQEGDVGALYHEQLALK S(-30.85)VGDES(30.85)WEQT(-37.41)QEGDVGALY(-139.8)HEQLALK 6 3 990.44487 0.38487 5600900 7.3549 1006400 137570 0 4355800 0 0 101060 223 206 992 992 63 75 647 420 Mix4_TiO2_Reinj_1_5 2991 647 420 Mix4_TiO2_Reinj_1_5 2991 O75694;O75694-2 O75694 O75694 >sp|O75694|NU155_HUMAN Nuclear pore complex protein Nup155 OS=Homo sapiens GN=NUP155 PE=1 SV=1;>sp|O75694-2|NU155_HUMAN Isoform 2 of Nuclear pore complex protein Nup155 OS=Homo sapiens GN=NUP155 0.919408 10.5722 0.5 0 0.0575968 43.486 0.5 0 0.488777 13.428 0.919408 10.5722 0.0396168 49.439 0 0 0 0 1 S SKAAPQSPSVPKK ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0396168 49.439 _AAPQpSPSVPK_ AAPQS(0.919)PS(0.081)VPK AAPQS(10.57)PS(-10.57)VPK 5 2 531.25499 -0.14148 1269100 285500 46852 0 936740 0 0 0 224 206 994 994 63 75 646 418 Mix4_TiO2_Reinj_1_1 2566 647 420 Mix4_TiO2_Reinj_1_5 2991 O75694;O75694-2 O75694 O75694 >sp|O75694|NU155_HUMAN Nuclear pore complex protein Nup155 OS=Homo sapiens GN=NUP155 PE=1 SV=1;>sp|O75694-2|NU155_HUMAN Isoform 2 of Nuclear pore complex protein Nup155 OS=Homo sapiens GN=NUP155 0.92298 10.7859 0.5 0 0.0575968 43.486 0.5 0 0.488777 13.428 0.92298 10.7859 0.0396168 49.439 0 0 0 0 1 S AAPQSPSVPKKPG 0.0396168 49.439 _AAPQSPpSVPK_ AAPQS(0.077)PS(0.923)VPK AAPQS(-10.79)PS(10.79)VPK 7 2 531.25499 -0.21795 422330 285500 46852 0 89972 0 0 0 225 210 42 42 2280 2578 20998 12868 Mix4_TiO2_Reinj_1_4 7722 20997 12866 Mix4_TiO2_Reinj_1_4 7706 O75821 O75821 O75821 >sp|O75821|EIF3G_HUMAN Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens GN=EIF3G PE=1 SV=2 0.960146 13.8215 0.499198 0 7.16143E-12 130.15 0.960146 13.8215 8.42139E-20 156.54 1 S LATGDTSPEPELL CK1;Proline-directed 0.05 8.42139E-20 156.54 _GIPLATGDTpSPEPELLPGAPLPPPK_ GIPLATGDT(0.04)S(0.96)PEPELLPGAPLPPPK GIPLAT(-45.69)GDT(-13.82)S(13.82)PEPELLPGAPLPPPK 10 2 1272.6535 0.55164 982580 0 0 0 982580 0 0 0 226 211 11 11 1;2 5;6 33 16 Mix4_TiO2_Reinj_1_2 6495 33 16 Mix4_TiO2_Reinj_1_2 6495 O75822 O75822 O75822 >sp|O75822|EIF3J_HUMAN Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens GN=EIF3J PE=1 SV=2 0.5 0 0.5 0 6.11169E-12 128.25 0.5 0 1.21403E-18 154.18 0.499984 0 0.00735154 73.933 0.492725 0 0.241146 51.751 1 S AAAAGDSDSWDAD 1.21403E-18 154.18 _(ac)AAAAAAAGDpSDSWDADAFSVEDPVRK_ AAAAAAAGDS(0.5)DS(0.5)WDADAFSVEDPVRK AAAAAAAGDS(0)DS(0)WDADAFS(-107.63)VEDPVRK 10 3 905.72385 -0.048619 630190 69403 0 0 359090 0 201710 0 227 211 13 13 1;2 5;6 24 10 Mix4_TiO2_Reinj_1_2 6933 33 16 Mix4_TiO2_Reinj_1_2 6495 O75822 O75822 O75822 >sp|O75822|EIF3J_HUMAN Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens GN=EIF3J PE=1 SV=2 0.989011 19.5424 0.90132 9.60647 6.11169E-12 128.25 0.989011 19.5424 1.21403E-18 154.18 0.499984 0 0.00735154 73.933 0.492725 0 0.241146 51.751 1 S AAGDSDSWDADAF 1.21403E-18 154.18 _(ac)AAAAAAAGDSDpSWDADAFSVEDPVR_ AAAAAAAGDS(0.011)DS(0.989)WDADAFSVEDPVR AAAAAAAGDS(-19.54)DS(19.54)WDADAFS(-63.79)VEDPVR 12 3 863.02553 0.071345 1577400 244180 0 0 1131600 0 201710 0 228 215 340 340 635;4822 730;5472 46045 28159 Mix4_TiO2_Reinj_1_3 2601 6048 3532 Mix4_TiO2_1_3 2187 O75909;O75909-1 O75909 O75909 >sp|O75909|CCNK_HUMAN Cyclin-K OS=Homo sapiens GN=CCNK PE=1 SV=2;>sp|O75909-1|CCNK_HUMAN Isoform 3 of Cyclin-K OS=Homo sapiens GN=CCNK 1 23.512 1 12.5838 0.00290593 113.81 1 6.24526 0.0104233 61.378 1 23.512 0.00222827 107.4 0 0 1 98.4366 0.00135024 98.437 1 11.672 0.00315311 79.264 1 S KRAVVVSPKEENK CDK1;CK2;ERK/MAPK;Proline-directed 0.0034 0.00290593 113.81 _RAVVVpSPKEENK_ RAVVVS(1)PKEENK RAVVVS(23.51)PKEENK 6 3 479.24834 0.30427 6125200 1205800 81588 0 4516800 0 161880 159130 229 215 324 324 3164 3591;3592 30012 18660 Mix4_TiO2_1_4 1394 30010 18657 Mix4_InSol_TiO2_1 1725 O75909;O75909-1;O75909-4 O75909 O75909 >sp|O75909|CCNK_HUMAN Cyclin-K OS=Homo sapiens GN=CCNK PE=1 SV=2;>sp|O75909-1|CCNK_HUMAN Isoform 3 of Cyclin-K OS=Homo sapiens GN=CCNK;>sp|O75909-4|CCNK_HUMAN Isoform 4 of Cyclin-K OS=Homo sapiens GN=CCNK 0.986538 21.6602 0.986538 21.6602 0.298161 21.66 0.999976 46.0644 0.049809 46.064 0.932276 10.7832 0.550021 10.783 0.997179 25.3687 0.25331 25.369 1 S QQPKKPSPQPSSP GSK3;Proline-directed 0.05 0.00113729 86.704 _KPpSPQPSSPR_ KPS(0.987)PQPS(0.007)S(0.007)PR KPS(21.66)PQPS(-21.66)S(-21.66)PR 3 2 580.77662 -0.84609 7210.2 7210.2 0 0 0 0 0 0 230 215 328 328 3164 3591;3592 30011 18658 Mix4_InSol_Tio2_Reinj_1 1766 30010 18657 Mix4_InSol_TiO2_1 1725 O75909;O75909-1;O75909-4 O75909 O75909 >sp|O75909|CCNK_HUMAN Cyclin-K OS=Homo sapiens GN=CCNK PE=1 SV=2;>sp|O75909-1|CCNK_HUMAN Isoform 3 of Cyclin-K OS=Homo sapiens GN=CCNK;>sp|O75909-4|CCNK_HUMAN Isoform 4 of Cyclin-K OS=Homo sapiens GN=CCNK 0.918213 10.5027 0.706106 1.46931 0.00117423 87.404 0.751168 4.86999 0.00306241 72.412 0.878806 8.25584 0.550021 10.783 0.918213 10.5027 0.0175194 56.756 1 S KPSPQPSSPRQVK CK1 0.143 0.00113729 86.704 _KPSPQPpSSPR_ KPSPQPS(0.918)S(0.082)PR KPS(-56.65)PQPS(10.5)S(-10.5)PR 7 2 580.77662 0.10239 481510 0 0 0 169980 0 0 311540 231 215 329 329 3164 3591;3592 30010 18657 Mix4_InSol_TiO2_1 1725 30010 18657 Mix4_InSol_TiO2_1 1725 O75909;O75909-1;O75909-4 O75909 O75909 >sp|O75909|CCNK_HUMAN Cyclin-K OS=Homo sapiens GN=CCNK PE=1 SV=2;>sp|O75909-1|CCNK_HUMAN Isoform 3 of Cyclin-K OS=Homo sapiens GN=CCNK;>sp|O75909-4|CCNK_HUMAN Isoform 4 of Cyclin-K OS=Homo sapiens GN=CCNK 0.971136 15.2692 0.998753 29.0347 0.00117423 87.404 0.936786 11.7083 0.00306241 72.412 0.971136 15.2692 0.00113729 86.704 0.97404 15.7301 0.25331 25.369 1 S PSPQPSSPRQVKR CDK1;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.00113729 86.704 _KPSPQPSpSPR_ KPSPQPS(0.029)S(0.971)PR KPS(-86.6)PQPS(-15.27)S(15.27)PR 8 2 580.77662 0.059403 1449000 0 0 0 1123000 0 326000 0 232 218 427 427 42 53 488 306 Mix4_TiO2_Reinj_1_3 1746 488 306 Mix4_TiO2_Reinj_1_3 1746 O76021 O76021 O76021 >sp|O76021|RL1D1_HUMAN Ribosomal L1 domain-containing protein 1 OS=Homo sapiens GN=RSL1D1 PE=1 SV=3 0.999237 31.1787 0.754368 6.9352 0.327871 26.244 0.999237 31.1787 0.023615 59.514 1 S SETPGKSPEKKPK CDK1;CDK2;CK1;Proline-directed 0.0057 0.023615 59.514 _AAESETPGKpSPEK_ AAESET(0.001)PGKS(0.999)PEK AAES(-59.51)ET(-31.18)PGKS(31.18)PEK 10 2 705.81105 -0.87557 322140 56538 0 0 265600 0 0 0 233 218 361 361 572 656 5419 3241 Mix4_InSol_Tio2_Reinj_1 7779 5421 3243 Mix4_TiO2_1_4 6487 O76021 O76021 O76021 >sp|O76021|RL1D1_HUMAN Ribosomal L1 domain-containing protein 1 OS=Homo sapiens GN=RSL1D1 PE=1 SV=3 0.960706 13.8827 0.800746 6.04087 5.94941E-06 106.82 0.810826 6.32065 0.00363903 78.158 0.404875 -1.67287 0.283196 36.899 0.960706 13.8827 0.683595 23.953 1 S VKATNESEDEIPQ CK2 0.117 5.94941E-06 106.82 _ATNEpSEDEIPQLVPIGK_ AT(0.039)NES(0.961)EDEIPQLVPIGK AT(-13.88)NES(13.88)EDEIPQLVPIGK 5 2 960.45353 0.41402 658300 58472 0 0 564730 0 0 35097 234 220 407 407 1037 1164 9814 6012 Mix4_TiO2_Reinj_1_5 6869 9814 6012 Mix4_TiO2_Reinj_1_5 6869 O76039 O76039 O76039 >sp|O76039|CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1 1 97.4531 1 70.1755 0.000128427 107.12 1 97.4531 1.0649E-08 139.5 0.93193 11.3643 0.283562 32.005 0 0 1 S NIPHLLSPKEAKS CDK1;CK2;Proline-directed 0.0057 1.0649E-08 139.5 _DLTNNNIPHLLpSPK_ DLTNNNIPHLLS(1)PK DLT(-97.45)NNNIPHLLS(97.45)PK 12 2 828.41127 1.009 1050400 248550 0 0 752930 0 48898 0 235 220 306 306 3527 3980 33279 20549 Mix4_TiO2_Reinj_1_5 2740 33279 20549 Mix4_TiO2_Reinj_1_5 2740 O76039 O76039 O76039 >sp|O76039|CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1 0.994773 22.7951 0.507995 0.138907 0.426014 24.972 0 0 0.994773 22.7951 0.0202055 62.219 0.772496 5.30906 1.13009 5.3091 0.893281 9.22747 0.22205 36.663 1 S QRLLDRSPSRSAK CDK1;CDK2;GSK3;NEK6;Proline-directed 0.0057 0.0202055 62.219 _LLDRpSPSR_ LLDRS(0.995)PS(0.005)R LLDRS(22.8)PS(-22.8)R 5 2 512.25278 -0.10222 2915100 217600 0 0 1802500 0 365940 529080 236 220 308 308 3527 3980 33276 20546 Mix4_TiO2_1_5 2158 33279 20549 Mix4_TiO2_Reinj_1_5 2740 O76039 O76039 O76039 >sp|O76039|CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1 0.5 0 0.5 0 0.426014 24.972 0 0 0.105655 -9.27616 0.0202055 62.219 0.227504 -5.30906 1.13009 5.3091 0.106719 -9.22747 0.22205 36.663 1 S LLDRSPSRSAKRK CAMK2;CHK1;CHK1/2;PKA/AKT;PKD 0.00111111 0.0202055 62.219 _LLDRpSPSR_ LLDRS(0.5)PS(0.5)R LLDRS(0)PS(0)R 7 2 512.25278 0.177 189220 189220 0 0 0 0 0 0 237 220 341 341 5526 6292 53942 32983 Mix4_TiO2_Reinj_1_5 6126 53942 32983 Mix4_TiO2_Reinj_1_5 6126 O76039 O76039 O76039 >sp|O76039|CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1 0.883186 8.78558 0.854176 7.6772 0.0151237 68.839 0 0 0.883186 8.78558 7.10851E-05 103.57 0 0 0 0 1 S LQSHHRSNSKDIQ CK1 0.143 7.10851E-05 103.57 _pSNSKDIQNLSVGLPR_ S(0.883)NS(0.117)KDIQNLSVGLPR S(8.79)NS(-8.79)KDIQNLS(-103.57)VGLPR 1 2 854.42491 0.25557 182510 48477 0 0 134030 0 0 0 238 223 448 448 520 586;587 4850 2932 Mix4_TiO2_1_5 4429 4858 2943 Mix4_TiO2_Reinj_1_5 5177 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.800783 6.04391 0.800783 6.04391 3.69273E-10 129.4 0.683739 3.41914 6.49281E-10 123.35 0.50314 0 2.02416E-15 145.15 0 0 0.535517 0.992283 2.43539E-06 111.26 0.481758 0 1.30144E-06 114.46 2 S NRSQKASQSRPNS CK1 0.143 2.02416E-15 145.15 _ApSQSRPNpSSALETLGGEK_ AS(0.801)QS(0.199)RPNS(0.984)S(0.016)ALETLGGEK AS(6.04)QS(-6.04)RPNS(17.87)S(-17.87)ALET(-76.76)LGGEK 2 2 996.42719 -0.10475 2600800 20.549 2285500 58089 0 202280 0 54884 0 239 223 450 450 520 586;587 4857 2942 Mix4_TiO2_Reinj_1_5 5170 4858 2943 Mix4_TiO2_Reinj_1_5 5177 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.977849 17.2376 0.889036 8.96645 3.69273E-10 129.4 0.916358 10.405 6.49281E-10 123.35 0.977849 17.2376 2.02416E-15 145.15 0 0 0.710981 3.91493 2.43539E-06 111.26 0.568458 1.20229 1.30144E-06 114.46 2 S SQKASQSRPNSSA GSK3 0.081 2.02416E-15 145.15 _ASQpSRPNpSSALETLGGEK_ AS(0.019)QS(0.978)RPNS(0.882)S(0.12)ALETLGGEK AS(-17.24)QS(17.24)RPNS(8.77)S(-8.77)ALET(-94.01)LGGEK 4 3 664.62055 -0.0054982 15441000 122.01 1519400 157090 0 12488000 0 843210 433780 240 223 454 454 520 586;587 4797 2893 Mix4_InSol_TiO2_1 5332 4815 2919 Mix4_TiO2_Reinj_1_5 4972 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.993341 21.7383 0.985852 19.7277 2.29616E-15 143.61 0.949835 12.9594 0.0917882 50.885 0.975979 17.161 7.21566E-21 160.45 0 0 0.993341 21.7383 1.99038E-06 112.53 0.899239 9.52978 1.30144E-06 114.46 1 S SQSRPNSSALETL CAMK2;CK1 0.042 7.21566E-21 160.45 _ASQSRPNpSSALETLGGEK_ ASQSRPNS(0.993)S(0.007)ALETLGGEK AS(-60.05)QS(-60.05)RPNS(21.74)S(-21.74)ALET(-68.84)LGGEK 8 2 956.44403 0.35177 11661000 92.133 1531200 74655 0 9512500 0 542210 0 241 223 455 455 520 586;587 4806 2904 Mix4_TiO2_1_5 4270 4815 2919 Mix4_TiO2_Reinj_1_5 4972 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.854076 7.67888 0.854076 7.67888 2.29616E-15 143.61 0.143832 -7.98992 6.49281E-10 123.35 0.435766 -0.844517 2.02416E-15 145.15 0 0 0.814664 7.57543 1.99038E-06 112.53 0.840867 10.0833 6.69842E-10 122.91 1 S QSRPNSSALETLG CK2 0.117 7.21566E-21 160.45 _ASQSRPNSpSALETLGGEK_ ASQSRPNS(0.146)S(0.854)ALETLGGEK AS(-52.16)QS(-37.05)RPNS(-7.68)S(7.68)ALET(-83.33)LGGEK 9 3 637.96511 -0.40733 2681400 21.187 1690700 0 0 0 0 773490 217230 242 223 13 13 2835 3229 27042 16893 Mix4_TiO2_1_5 6134 27043 16894 Mix4_TiO2_Reinj_1_5 6979 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.99469 22.7256 0.99469 22.7256 0.0614262 43.436 0 0 0.970527 15.1759 0.00795703 61.279 0 0 0 0 1 S RRILRLSTFEKRK CK2;NEK6;PKA 0.042 0.00795703 61.279 _ILRLpSTFEK_ ILRLS(0.995)T(0.005)FEK ILRLS(22.73)T(-22.73)FEK 5 2 593.81521 -0.12577 612860 84733 0 0 528130 0 0 0 243 223 438 438 2894;4764 3297;5411 45460 27812 Mix4_TiO2_Reinj_2_1 2487 45434 27774 Mix4_InSol_TiO2_1 3590 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 1 61.2784 1 140.195 4.76676E-22 196.36 1 187.513 2.40578E-16 187.51 1 147.979 1.62293E-22 208.32 1 61.2784 0.0237503 61.278 1 4.32341 9.52122E-23 210.88 1 20.6312 3.12778E-16 185.2 1 S EQGGDLSPAANRS Proline-directed 0.05 9.52122E-23 210.88 _QVAEQGGDLpSPAANR_ QVAEQGGDLS(1)PAANR QVAEQGGDLS(61.28)PAANR 10 2 796.85686 -0.032202 67181000 136.73 7465200 722990 0 34299000 88054 13448000 11157000 244 223 951 951 3713;3714 4186;4188 35058 21718 Mix4_InSol_TiO2_2 2476 35000 21677 Mix4_InSol_TiO2_1 3403 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.926097 11.6657 0.832943 7.91832 4.48952E-16 180.84 0.442195 -0.974183 3.69829E-16 183.37 0.671198 5.34414 4.65341E-30 221.14 0.0157179 -17.9369 0.00471803 77.958 0.926097 11.6657 1.86617E-30 228.71 0.811189 6.33109 4.48952E-16 180.84 1 S AECPNPSTPSKAA 1.86617E-30 228.71 _LSEEAECPNPpSTPSKAAK_ LSEEAECPNPS(0.926)T(0.063)PS(0.011)KAAK LS(-51.93)EEAECPNPS(11.67)T(-11.67)PS(-19.34)KAAK 11 3 665.96249 0.18397 23115000 50.869 3521400 0 0 14698000 0 351720 4544000 245 223 954 954 3713;3714 4186;4188 35004 21682 Mix4_InSol_TiO2_5 1605 35000 21677 Mix4_InSol_TiO2_1 3403 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.788478 6.43497 0.674076 5.19056 4.48952E-16 180.84 0.00441445 -20.9816 3.69829E-16 183.37 0.322454 -0.418741 4.65341E-30 221.14 0.00684893 -21.5446 0.00471803 77.958 0.788478 6.43497 1.86617E-30 228.71 0.59251 1.77716 4.48952E-16 180.84 1 S PNPSTPSKAAKFF CK1 0.081 1.86617E-30 228.71 _LSEEAECPNPSTPpSK_ LSEEAECPNPS(0.032)T(0.179)PS(0.788)K LS(-98.24)EEAECPNPS(-13.87)T(-6.43)PS(6.43)K 14 2 863.3555 -0.11865 386530 0.85061 257800 0 0 0 0 43099 85623 246 223 191 191 4837 5491;5492;5494;5495 46194 28237 Mix4_TiO2_1_5 7356 46215 28247 Mix4_TiO2_Reinj_1_5 8962 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.991905 20.8976 0.991905 20.8976 0.000143742 94.244 0.97162 15.4566 9.58652E-17 142.66 1 S TLQKRDSFIGTPY AURORA;AURORA-A;CHK1;PKA;PKD 0.006142092 9.58652E-17 142.66 _RDpSFIGTPYWMAPEVVM(ox)CETM(ox)K_ RDS(0.992)FIGT(0.008)PYWMAPEVVMCETMK RDS(20.9)FIGT(-20.9)PY(-48.31)WMAPEVVMCET(-94.24)MK 3 3 920.7241 -0.036678 1353800 0.78151 186250 0 0 1167600 0 0 0 247 223 392 392 5463 6217 53316 32578 Mix4_TiO2_Reinj_1_5 6825 53316 32578 Mix4_TiO2_Reinj_1_5 6825 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.883772 9.0125 0 0 0.883772 9.0125 0.000264221 84.003 0.724726 4.5035 0.277015 50.343 0.193867 -2.93715 1.4839 26.392 1 S RSLQTTSPPVVAP Proline-directed 0.05 0.000264221 84.003 _SLQTTpSPPVVAPGNENGLAVPVPLRK_ SLQT(0.005)T(0.111)S(0.884)PPVVAPGNENGLAVPVPLRK S(-35.82)LQT(-22.43)T(-9.01)S(9.01)PPVVAPGNENGLAVPVPLRK 6 3 907.81602 0.027593 690110 0 0 0 464920 0 225190 0 248 223 417 417 5673 6460;6461 55593 34074 Mix4_InSol_Tio2_Reinj_1 3279 55594 34075 Mix4_InSol_Tio2_Reinj_2 2264 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 1 69.0952 0.868763 8.20845 0.741041 8.2084 0.939936 11.9448 0.475479 11.945 0.999765 36.281 0.134749 36.281 0.999999 59.5466 0.00619783 65.676 1 69.0952 0.00359231 72.189 1 S RKSRPVSMDARIQ CAMK2;CK1 0.042 0.00359231 72.189 _SRPVpSMDAR_ SRPVS(1)MDAR S(-69.1)RPVS(69.1)MDAR 5 2 549.74172 0.25126 3220800 50332 0 0 813300 0 1264500 1092700 249 224 364 364 2301 2603 21304 13061 Mix4_TiO2_Reinj_1_5 3868 21301 13058 Mix4_TiO2_1_5 3308 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 1 75.3028 1 75.2808 3.69304E-09 150.73 0 0 1 75.3028 9.5202E-07 127.48 0 0 0.999982 47.3476 0.0195864 64.205 0 0 1 S DDTEEPSPPEDKM CK1;CK2;Proline-directed 0.05 3.69304E-09 150.73 _GLDDTEEPpSPPEDK_ GLDDTEEPS(1)PPEDK GLDDT(-75.3)EEPS(75.3)PPEDK 9 2 804.81927 -0.0024207 5514400 4.455 1499900 0 0 3589200 0 425420 0 250 224 415 415 3225 3657 30543 18976 Mix4_InSol_TiO2_1 1900 30544 18977 Mix4_InSol_Tio2_Reinj_1 1885 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.809242 9.13967 0.809242 9.13967 0.822521 9.4379 0.320063 -3.27108 0.119612 51.385 1 S HTKRKSSTMVKEG CAMK2;PKA 0.003024 0.119612 51.385 _KSpSTMVK_ KS(0.092)S(0.809)T(0.099)MVK KS(-9.44)S(9.14)T(-9.14)MVK 3 2 430.701 0.60377 45420 0 0 0 0 0 45420 0 251 224 41 41 3725;5999 4199;4200;6839 35139 21759 Mix4_TiO2_1_3 5010 35137 21757 Mix4_InSol_Tio2_Reinj_1 6098 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.999999 58.9726 0.999999 58.9726 0.000223924 97.946 0 0 0.972067 19.0089 0.552272 23.933 0 0 0.992812 21.404 0.00209463 85.238 0.999021 30.0906 6.62696E-07 119.31 1 S GLSARLSNGSFSA CK1;PKA 0.042 6.62696E-07 119.31 _LpSNGSFSAPSLTNSR_ LS(1)NGSFSAPSLTNSR LS(58.97)NGS(-58.97)FS(-88.37)APS(-97.95)LT(-97.95)NS(-97.95)R 2 2 809.36706 1.7888 3781900 716130 0 0 241720 0 1796600 1027500 252 224 44 44 3725;5999 4199;4200;6839 59230 35985 Mix4_InSol_TiO2_1 6881 35137 21757 Mix4_InSol_Tio2_Reinj_1 6098 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.94411 15.4756 0.999648 34.5363 6.41645E-05 105.02 0 0 0.999497 32.9813 7.83547E-05 102.09 0 0 0.94411 15.4756 0.00209463 85.238 0.27458 -1.81578 6.62696E-07 119.31 1 S ARLSNGSFSAPSL CK1 0.081 6.62696E-07 119.31 _TGLSARLSNGpSFSAPSLTNSR_ T(0.001)GLS(0.027)ARLS(0.027)NGS(0.944)FS(0.001)APSLTNSR T(-29.37)GLS(-15.48)ARLS(-15.48)NGS(15.48)FS(-28.68)APS(-69.26)LT(-72.37)NS(-72.37)R 11 3 735.02162 -0.4498 453130 0 0 0 0 0 453130 0 253 224 213 213 3726;4950;4951;5025 4201;5627;5628;5629;5716 47611 29079 Mix4_TiO2_2_2 5704 47618 29088 Mix4_TiO2_Reinj_1_5 6768 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.999995 52.62 0.99999 50.1844 1.12933E-08 122.39 0.999995 52.62 1.14331E-08 122.21 0.999991 50.4621 3.71517E-09 132.45 0 0 0 0 0 0 1 S VRKRRLSNVSLPG CAMK2;PKA;PKA/AKT 0.001764 3.71517E-09 132.45 _RLpSNVSLPGPGLSVPR_ RLS(1)NVSLPGPGLSVPR RLS(52.62)NVS(-52.62)LPGPGLS(-108.89)VPR 3 2 864.96146 -0.39464 35847000 8157200 307620 0 27383000 0 0 0 254 224 216 216 3726;4950;4951;5025 4201;5627;5628;5629;5716 35166 21766 Mix4_TiO2_Reinj_1_5 6857 47618 29088 Mix4_TiO2_Reinj_1_5 6768 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.997877 26.74 0.921694 10.708 1.12933E-08 122.39 0.0253347 -15.8514 1.14331E-08 122.21 0.997877 26.74 3.71517E-09 132.45 0 0 0 0 0 0 1 S RRLSNVSLPGPGL CK1 0.081 3.71517E-09 132.45 _LSNVpSLPGPGLSVPR_ LS(0.002)NVS(0.998)LPGPGLSVPR LS(-26.74)NVS(26.74)LPGPGLS(-50.4)VPR 5 2 786.91091 0.38775 332910 102830 0 0 230080 0 0 0 255 224 6 6 5106 5808 49340 30093 Mix4_InSol_Tio2_Reinj_1 1865 49340 30093 Mix4_InSol_Tio2_Reinj_1 1865 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.999996 54.5753 0.999984 49.376 0.00333558 118.23 0 0 0.999572 33.7052 0.00227656 124.77 0 0 0.998792 29.1753 0.000359618 136.61 0.999996 54.5753 0.000164721 143.28 1 S _MSANNSPPSAQK CK1;Proline-directed 0.05 0.000164721 143.28 _(ac)SANNpSPPSAQK_ SANNS(1)PPSAQK S(-65.58)ANNS(54.58)PPS(-54.58)AQK 5 2 611.75862 -0.2248 2144400 18.672 303530 0 0 1111900 0 353090 375920 256 224 27 27 5833 6651;6652 57503 35005 Mix4_TiO2_Reinj_1_5 7498 57504 35006 Mix4_TiO2_Reinj_1_5 7503 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.93195 11.8728 0.759336 8.00053 0.000517808 80.89 0 0 0.93195 11.8728 3.59977E-11 128.57 0.550556 1.51737 6.30099E-07 105.66 0.800091 7.37271 0.000409925 84.653 1 S AVLPAASPCSSPK GSK3;Proline-directed 0.05 3.59977E-11 128.57 _SVLPTAIPAVLPAApSPCSSPK_ SVLPTAIPAVLPAAS(0.932)PCS(0.061)S(0.008)PK S(-100.27)VLPT(-100.27)AIPAVLPAAS(11.87)PCS(-11.87)S(-20.94)PK 15 3 715.03381 -0.18584 2597600 504620 0 0 1560400 0 246450 286090 257 224 30 30 5833 6651;6652 57529 35029 Mix4_TiO2_Reinj_1_6 6637 57527 35024 Mix4_TiO2_Reinj_1_5 7631 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.929721 11.0796 0.911855 9.86526 7.56891E-11 118.83 0 0 0.929721 11.0796 5.31017E-11 124.37 0.388208 -1.51737 6.30099E-07 105.66 0.146511 -7.37271 0.000409925 84.653 2 S PAASPCSSPKTGL CK1 0.081 5.31017E-11 124.37 _SVLPTAIPAVLPAApSPCpSSPK_ SVLPTAIPAVLPAAS(0.971)PCS(0.93)S(0.099)PK S(-91.82)VLPT(-91.82)AIPAVLPAAS(14.99)PCS(11.08)S(-11.08)PK 18 2 1112.0302 0.51192 8093700 2035000 0 0 6058600 0 0 0 258 224 31 31 5833 6651;6652 57505 35008 Mix4_TiO2_Reinj_1_5 7614 57504 35006 Mix4_TiO2_Reinj_1_5 7503 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.787507 6.71917 0.895978 8.81578 7.56891E-11 118.83 0 0 0.787507 6.71917 3.59977E-11 128.57 0.0612359 -9.53796 6.30099E-07 105.66 0.138422 -7.18026 0.000409925 84.653 1 S AASPCSSPKTGLS CDK1;CK1;Polo box;Proline-directed 0.00405 3.59977E-11 128.57 _SVLPTAIPAVLPAASPCSpSPK_ SVLPTAIPAVLPAAS(0.045)PCS(0.168)S(0.788)PK S(-61.58)VLPT(-61.58)AIPAVLPAAS(-12.44)PCS(-6.72)S(6.72)PK 19 2 1072.0471 -0.32376 522620 50501 0 0 472120 0 0 0 259 224 735 735 5865 6689 57869 35179 Mix4_TiO2_Reinj_1_3 7657 57868 35178 Mix4_TiO2_1_5 6627 O94806;Q15139 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|Q15139|KPCD1_HUMAN Serine/threonine-protein kinase D1 OS=Homo sapiens GN=PRKD1 PE=1 SV=2 1 76.6785 1 74.9237 2.88916E-10 155.47 0 0 1 76.6785 4.75942E-07 124.43 0 0 0 0 1 S EKSFRRSVVGTPA AURORA;AURORA-1;CK1;NIMA;PKA 0.001741464 2.88916E-10 155.47 _pSVVGTPAYLAPEVLR_ S(1)VVGTPAYLAPEVLR S(76.68)VVGT(-76.68)PAY(-124.43)LAPEVLR 1 2 826.42639 0.096475 1097200 268760 0 0 828420 0 0 0 260 224 37 37 5999 6839 59233 35988 Mix4_InSol_Tio2_Reinj_1 6844 59230 35985 Mix4_InSol_TiO2_1 6881 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.417106 1.81578 0 0 0.22298 -4.10658 0.00666525 72.37 0.417106 1.81578 0.00700182 71.975 1 S SPKTGLSARLSNG GSK3 0.081 0.00666525 72.37 _TGLpSARLSNGSFSAPSLTNSR_ T(0.104)GLS(0.417)ARLS(0.182)NGS(0.275)FS(0.022)APSLTNSR T(-6.04)GLS(1.82)ARLS(-3.59)NGS(-1.82)FS(-12.75)APS(-40.16)LT(-40.16)NS(-40.16)R 4 3 735.02162 -0.75029 0 0 0 0 0 0 0 0 261 224 391 391 6033 6881;6882 59633 36189 Mix4_TiO2_Reinj_1_5 6302 59633 36189 Mix4_TiO2_Reinj_1_5 6302 O94806;O94806-2;Q15139 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3;>sp|Q15139|KPCD1_HUMAN Serine/threonine-protein kinase D1 OS=Homo 0.920135 10.616 0.904424 9.76027 0.00115151 93.228 0.920135 10.616 5.47269E-07 131.74 0.00110733 -28.7464 0.0413215 56.068 0.488781 0 0.0749211 48.088 1 S EAVKTISPSTSNN GSK3;Proline-directed 0.05 5.47269E-07 131.74 _TIpSPSTSNNIPLMR_ T(0.08)IS(0.92)PSTSNNIPLMR T(-10.62)IS(10.62)PS(-47.19)T(-58.05)S(-66.25)NNIPLMR 3 2 805.88403 1.1268 708080 350450 0 0 357630 0 0 0 262 224 395 395 6033 6881;6882 59630 36184 Mix4_InSol_TiO2_1 6777 59633 36189 Mix4_TiO2_Reinj_1_5 6302 O94806;O94806-2;Q15139 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3;>sp|Q15139|KPCD1_HUMAN Serine/threonine-protein kinase D1 OS=Homo 0.829697 9.11733 6.40702E-05 -41.4898 0.00115151 93.228 2.18283E-07 -66.2483 5.47269E-07 131.74 0.829697 9.11733 0.0413215 56.068 0.00065149 -28.7521 0.0749211 48.088 1 S TISPSTSNNIPLM CK1 0.143 5.47269E-07 131.74 _TISPSTpSNNIPLMR_ TIS(0.001)PS(0.068)T(0.102)S(0.83)NNIPLMR T(-51.76)IS(-28.75)PS(-10.89)T(-9.12)S(9.12)NNIPLMR 7 2 805.88403 -0.018737 168470 0 0 0 0 0 168470 0 263 225 244 244 3356;4933 3796;5609 31627 19562 Mix4_TiO2_1_3 3306 31627 19562 Mix4_TiO2_1_3 3306 O94808 O94808 O94808 >sp|O94808|GFPT2_HUMAN Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens GN=GFPT2 PE=1 SV=3 0.99992 40.9496 0.99992 40.9496 0.000143384 114.92 0.999437 32.4957 0.00362814 84.682 0.999695 35.1543 0.000143381 114.92 0.999353 31.8891 0.00361633 84.737 1 S RMKRLDSSACLHA CAMK2;CHK1;PKA 0.003024 0.000143384 114.92 _LDpSSACLHAVGDK_ LDS(1)SACLHAVGDK LDS(40.95)S(-40.95)ACLHAVGDK 3 2 726.81307 -0.38551 3931500 658190 0 0 2881000 0 247060 145230 264 225 245 245 3356;4933 3796;5609 31626 19561 Mix4_InSol_Tio2_Reinj_2 3165 31627 19562 Mix4_TiO2_1_3 3306 O94808 O94808 O94808 >sp|O94808|GFPT2_HUMAN Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens GN=GFPT2 PE=1 SV=3 0.545546 0.793413 0.5 0 0.000143384 114.92 0.5 0 0.00362814 84.682 0.289705 -3.89483 0.000143381 114.92 0.545546 0.793413 0.00361633 84.737 1 S MKRLDSSACLHAV NEK6 0.076 0.000143384 114.92 _LDSpSACLHAVGDK_ LDS(0.454)S(0.546)ACLHAVGDK LDS(-0.79)S(0.79)ACLHAVGDK 4 2 726.81307 0.21734 1109700 126950 0 0 869300 0 0 113460 265 228 458 458 2409;2985 2730;3396 22502 14040 Mix4_TiO2_Reinj_1_3 1066 28476 17666 Mix4_TiO2_Reinj_1_3 1063 O94874;O94874-2;O94874-3 O94874 O94874 >sp|O94874|UFL1_HUMAN E3 UFM1-protein ligase 1 OS=Homo sapiens GN=KIAA0776 PE=1 SV=2;>sp|O94874-2|UFL1_HUMAN Isoform 2 of E3 UFM1-protein ligase 1 OS=Homo sapiens GN=KIAA0776;>sp|O94874-3|UFL1_HUMAN Isoform 3 of E3 UFM1-protein ligase 1 OS=Homo sapiens GN= 1 70.8538 0 0 1 70.8538 1.78126E-12 147.55 0.999994 52.2127 5.46593E-06 110.45 0.996611 25.6499 0.278692 36.462 1 S GRKDDDSDDESQS CK2;GSK3 0.081 1.78126E-12 147.55 _GRKDDDpSDDESQSSHTGK_ GRKDDDS(1)DDESQSSHTGK GRKDDDS(70.85)DDES(-70.85)QS(-100.82)S(-100.82)HT(-115.75)GK 7 3 681.93443 -0.018828 666190 0 0 0 317080 0 149620 199480 266 229 138 138 4996 5680 48210 29465 Mix4_TiO2_Reinj_1_5 6968 48210 29465 Mix4_TiO2_Reinj_1_5 6968 O94901;O94901-5;O94901-3;O94901-2 O94901 O94901 >sp|O94901|SUN1_HUMAN SUN domain-containing protein 1 OS=Homo sapiens GN=SUN1 PE=1 SV=3;>sp|O94901-5|SUN1_HUMAN Isoform 5 of SUN domain-containing protein 1 OS=Homo sapiens GN=SUN1;>sp|O94901-3|SUN1_HUMAN Isoform 3 of SUN domain-containing protein 1 OS=Hom 1 37.6215 1 37.6215 0.114818 37.621 1 S PPVLDESWIREQT NEK6;PLK1 0.033462 0.114818 37.621 _RPPVLDEpSWIR_ RPPVLDES(1)WIR RPPVLDES(37.62)WIR 8 2 724.35831 0.21292 122240 0 0 0 122240 0 0 0 267 231 1971 1971 2847 3243 27162 16989 Mix4_TiO2_Reinj_1_1 1941 27162 16989 Mix4_TiO2_Reinj_1_1 1941 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.948085 12.9932 0.499665 0 0.00107991 84.371 0.948085 12.9932 0.00195946 94.544 0.495681 0 0.440916 18.272 1 S GRINHSSSLARTR 0.00195946 94.544 _INHSpSSLAR_ INHS(0.004)S(0.948)S(0.048)LAR INHS(-23.41)S(12.99)S(-12.99)LAR 5 2 532.74786 -0.096554 1083500 0 0 0 1083500 0 0 0 268 231 1972 1972 2847 3243 27161 16984 Mix4_TiO2_1_1 1539 27162 16989 Mix4_TiO2_Reinj_1_1 1941 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.499665 0 0.499665 0 0.00107991 84.371 0.49963 0 0.00195946 94.544 0.495681 0 0.440916 18.272 1 S RINHSSSLARTRS 0.00195946 94.544 _INHSpSSLAR_ INHS(0.001)S(0.5)S(0.5)LAR INHS(-28.73)S(0)S(0)LAR 6 2 532.74786 0.31657 0 0 0 0 0 0 0 0 269 231 1914 1914 3227;5785 3659;6591 30556 18999 Mix4_TiO2_1_1 5508 30556 18999 Mix4_TiO2_1_1 5508 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.499665 0 0.499665 0 2.1074E-08 117.09 0.49716 0 0.250353 49.369 0 0 0.447259 -0.916507 0.000276208 87.162 0.427058 -0.836679 0.000320367 85.293 1 S YAANRKSTGQLNL PKA 0.042 2.1074E-08 117.09 _KpSTGQLNLSTSPINSSSYLGYNSNAR_ KS(0.5)T(0.5)GQLNLSTSPINSSSYLGYNSNAR KS(0)T(0)GQLNLS(-31.76)T(-31.76)S(-50.28)PINS(-91.82)S(-98.77)S(-104.99)Y(-111.43)LGY(-117.09)NS(-117.09)NAR 2 3 947.11345 -2.2277 0 0 0 0 0 0 0 0 270 231 844 844 3666 4133 34460 21416 Mix4_TiO2_Reinj_1_1 6856 34460 21416 Mix4_TiO2_Reinj_1_1 6856 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 1 145.835 1 147.681 1.49068E-16 170.29 0 0 1 145.835 1.79779E-26 208.87 0 0 1 S PQVDINSPINAKK Proline-directed 0.05 1.79779E-26 208.87 _LQLLSPQVDINpSPINAK_ LQLLSPQVDINS(1)PINAK LQLLS(-145.83)PQVDINS(145.83)PINAK 12 2 965.5059 0.50561 286900 51410 0 0 235490 0 0 0 271 231 1957 1957 5032;5042;5534 5723;5734;5735;6304;6305 48592 29701 Mix4_TiO2_Reinj_1_1 3266 54137 33137 Mix4_TiO2_Reinj_1_1 5392 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.997348 25.7525 0.694603 3.56871 0.00129389 89.67 0.927434 11.0655 0.476304 13.967 0.997348 25.7525 0.00129389 89.67 0 0 0.11439 -8.88855 0.00255261 85.052 0.05764 -12.1349 0.00436907 68.382 1 S RGDRRRSNTLDIM CAMK2;PKA;PKA/AKT 0.00111111 0.00129389 89.67 _RRpSNTLDIM(ox)DGR_ RRS(0.997)NT(0.003)LDIMDGR RRS(25.75)NT(-25.75)LDIMDGR 3 3 510.56786 0.59899 512530 53339 3612.5 0 455580 0 0 0 272 231 1939 1939 5527 6293 53951 32984 Mix4_InSol_TiO2_1 7161 53952 32985 Mix4_InSol_TiO2_1 7169 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.484956 0 0 0 0 0 0 0 0.484956 0 0.0061751 80.754 0.413225 -1.10535 0.0808961 42.224 1 S YNSNARSNSLRLS CK1 0.143 0.0061751 80.754 _pSNSLRLSLIGDR_ S(0.485)NS(0.485)LRLS(0.03)LIGDR S(0)NS(0)LRLS(-12.07)LIGDR 1 2 705.85867 0.16815 0 0 0 0 0 0 0 0 273 231 1941 1941 5527 6293 53954 32987 Mix4_InSol_Tio2_Reinj_1 7174 53952 32985 Mix4_InSol_TiO2_1 7169 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.997824 27.3823 0 0 0 0 0 0 0.960498 15.0428 0.0061751 80.754 0.997824 27.3823 0.0808961 42.224 1 S SNARSNSLRLSLI CAMK2;GSK3;PKC 0.001764 0.0061751 80.754 _SNpSLRLSLIGDR_ S(0.002)NS(0.998)LRLSLIGDR S(-27.38)NS(27.38)LRLS(-34.51)LIGDR 3 3 470.90821 -0.79205 379360 0 0 0 0 0 78385 300980 274 231 2272 2272 6311 7211 63136 38479 Mix4_InSol_TiO2_1 6028 63136 38479 Mix4_InSol_TiO2_1 6028 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.973972 15.757 0.188736 -6.30943 6.35418E-06 116.92 0 0 0.0207402 -16.7394 2.65724E-09 145.32 0 0 0.973972 15.757 2.59758E-09 145.58 0.397772 -1.31164 7.25658E-08 135.5 1 S YGGDTGSPEISFT GSK3;Proline-directed 0.05 2.59758E-09 145.58 _TYGGDTGpSPEISFTK_ TYGGDT(0.026)GS(0.974)PEISFTK T(-82.82)Y(-124.65)GGDT(-15.76)GS(15.76)PEIS(-38)FT(-62.04)K 8 2 820.348 -0.34135 191700 0 0 0 0 0 191700 0 275 233 119 119 2659;4907 3025;5579 47087 28789 Mix4_TiO2_Reinj_1_4 1556 47087 28789 Mix4_TiO2_Reinj_1_4 1556 O94921;O94921-2;O94921-3 O94921 O94921 >sp|O94921|CDK14_HUMAN Cell division protein kinase 14 OS=Homo sapiens GN=CDK14 PE=1 SV=3;>sp|O94921-2|CDK14_HUMAN Isoform 2 of Cell division protein kinase 14 OS=Homo sapiens GN=CDK14;>sp|O94921-3|CDK14_HUMAN Isoform 3 of Cell division protein kinase 14 O 0.872749 8.52183 0.00250551 -25.2172 0.259747 25.217 0.872749 8.52183 0.0173041 60.204 0 0 0 0 0 0 2 S PKVRRHSSPSSPT CAMK2;GSK3;PKA 0.004788 0.0173041 60.204 _RHpSSPSpSPTSPK_ RHS(0.873)S(0.129)PS(0.141)S(0.857)PTSPK RHS(8.52)S(-8.52)PS(-7.99)S(7.99)PT(-31.9)S(-33.9)PK 3 2 714.28944 -0.072658 38423 0 0 0 38423 0 0 0 276 233 123 123 2659;4907 3025;5579 24801 15357 Mix4_TiO2_Reinj_1_4 1578 24801 15357 Mix4_TiO2_Reinj_1_4 1578 O94921;O94921-2;O94921-3 O94921 O94921 >sp|O94921|CDK14_HUMAN Cell division protein kinase 14 OS=Homo sapiens GN=CDK14 PE=1 SV=3;>sp|O94921-2|CDK14_HUMAN Isoform 2 of Cell division protein kinase 14 OS=Homo sapiens GN=CDK14;>sp|O94921-3|CDK14_HUMAN Isoform 3 of Cell division protein kinase 14 O 0.870792 8.43865 0.832942 8.08342 0.259747 25.217 0.870792 8.43865 0.0726295 41.924 0 0 0 0 0 0 1 S RHSSPSSPTSPKF CK1;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0726295 41.924 _HSSPSpSPTSPK_ HSSPS(0.125)S(0.871)PT(0.002)S(0.002)PK HS(-40.55)S(-33.56)PS(-8.44)S(8.44)PT(-26.12)S(-26.69)PK 6 2 596.25572 0.55173 212900 27048 0 0 185850 0 0 0 277 235 373 373 532 605 4993 3015 Mix4_TiO2_Reinj_1_3 4671 4993 3015 Mix4_TiO2_Reinj_1_3 4671 O94929;O94929-3;O94929-2 O94929 O94929 >sp|O94929|ABLM3_HUMAN Actin-binding LIM protein 3 OS=Homo sapiens GN=ABLIM3 PE=1 SV=3;>sp|O94929-3|ABLM3_HUMAN Isoform 3 of Actin-binding LIM protein 3 OS=Homo sapiens GN=ABLIM3;>sp|O94929-2|ABLM3_HUMAN Isoform 2 of Actin-binding LIM protein 3 OS=Homo sap 0.846323 7.4095 0 0 0.846323 7.4095 0.0352794 57.503 1 S RQRRASSPGYIDS CAMK2;Polo box;Proline-directed 0.00405 0.0352794 57.503 _ASpSPGYIDSPTYSR_ AS(0.154)S(0.846)PGYIDSPTYSR AS(-7.41)S(7.41)PGY(-55.53)IDS(-57.5)PT(-57.5)Y(-57.5)S(-57.5)R 3 2 790.83506 0.12267 130410 0 0 0 130410 0 0 0 278 237 1255 1255 6669 7635 67617 41508 Mix4_TiO2_Reinj_1_1 4195 67617 41508 Mix4_TiO2_Reinj_1_1 4195 O94964-2;O94964;O94964-3 O94964-2 O94964-2 >sp|O94964-2|CT117_HUMAN Isoform 2 of Uncharacterized protein C20orf117 OS=Homo sapiens GN=C20orf117;>sp|O94964|CT117_HUMAN Uncharacterized protein C20orf117 OS=Homo sapiens GN=C20orf117 PE=1 SV=2;>sp|O94964-3|CT117_HUMAN Isoform 3 of Uncharacterized prote 0.999285 31.6531 0.60009 4.77284 0.843509 4.7728 0 0 0.999285 31.6531 0.0566981 44.933 0 0 0.980678 19.3209 0.27569 20.964 0 0 1 S GIRVYYSPPVARR 14-3-3 binding;Proline-directed 0.0001533 0.0566981 44.933 _VYYpSPPVAR_ VYY(0.001)S(0.999)PPVAR VY(-44.93)Y(-31.65)S(31.65)PPVAR 4 2 566.26536 -0.34012 112430 17111 0 0 95314 0 0 0 279 238 799 799 430;431 492;493 4095 2449 Mix4_TiO2_Reinj_1_5 2281 4095 2449 Mix4_TiO2_Reinj_1_5 2281 O94979-8;O94979;O94979-2;O94979-4;O94979-3;O94979-6;O94979-7 O94979-8 O94979-8 >sp|O94979-8|SC31A_HUMAN Isoform 8 of Protein transport protein Sec31A OS=Homo sapiens GN=SEC31A;>sp|O94979|SC31A_HUMAN Protein transport protein Sec31A OS=Homo sapiens GN=SEC31A PE=1 SV=3;>sp|O94979-2|SC31A_HUMAN Isoform 2 of Protein transport protein Sec 1 39.7938 0.973084 15.5815 0.222752 39.229 1 39.7938 0.0723342 39.794 1 S PVAGHESPKIPYE CDK1;Proline-directed 0.0057 0.0723342 39.794 _AQGEPVAGHEpSPK_ AQGEPVAGHES(1)PK AQGEPVAGHES(39.79)PK 11 2 693.80611 0.014688 1317300 254620 0 0 1062700 0 0 0 280 239 1549 1549 4919 5593 47220 28843 Mix4_InSol_Tio2_Reinj_1 2763 47220 28843 Mix4_InSol_Tio2_Reinj_1 2763 O95071 O95071 O95071 >sp|O95071|UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens GN=UBR5 PE=1 SV=2 0.999029 30.1253 0 0 0.985528 18.3314 0.1287 36.713 0.978991 16.6838 0.0622847 43.164 0.999029 30.1253 0.0439252 48.977 1 S PQQRRISQSQPVR CAMK2;PKA;PKA/AKT 0.00111111 0.0439252 48.977 _RIpSQSQPVR_ RIS(0.999)QS(0.001)QPVR RIS(30.13)QS(-30.13)QPVR 3 2 575.79006 0.34281 313990 0 0 0 143970 0 86504 83521 281 240 103 103 5647 6433 55142 33744 Mix4_InSol_TiO2_1 4963 55142 33744 Mix4_InSol_TiO2_1 4963 O95155;O95155-2 O95155 O95155 >sp|O95155|UBE4B_HUMAN Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B PE=1 SV=1;>sp|O95155-2|UBE4B_HUMAN Isoform 2 of Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B 0.881562 8.71895 0.881562 8.71895 0.0810501 43.908 0 0 1 S SQSLSRSQSMDID CK1;NEK6 0.076 0.0810501 43.908 _pSQSMDIDGVSCEK_ S(0.882)QS(0.118)MDIDGVSCEK S(8.72)QS(-8.72)MDIDGVS(-43.91)CEK 1 2 768.29131 1.2365 31566 0 0 0 0 0 31566 0 282 240 87 87 5650 6436 55164 33760 Mix4_InSol_Tio2_Reinj_1 5928 55167 33763 Mix4_TiO2_Reinj_1_5 5639 O95155;O95155-2 O95155 O95155 >sp|O95155|UBE4B_HUMAN Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B PE=1 SV=1;>sp|O95155-2|UBE4B_HUMAN Isoform 2 of Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B 0.877225 10.7923 0.061608 -10.9909 0.00537083 75.972 0.00231398 -26.0888 7.46656E-26 163.5 0 0 0.00735416 -20.3061 0.000260404 80.734 0.877225 10.7923 0.000177763 86.481 1 S GVSSLSSSPSNSL CK1 0.081 7.46656E-26 163.5 _SQSSEGVSSLSpSSPSNSLETQSQSLSR_ SQSSEGVS(0.002)S(0.001)LS(0.073)S(0.877)S(0.043)PS(0.002)NS(0.001)LETQSQSLSR S(-44.43)QS(-43.86)S(-43.86)EGVS(-26.51)S(-27.84)LS(-10.79)S(10.79)S(-13.08)PS(-25.63)NS(-31.7)LET(-53.23)QS(-60.82)QS(-71.83)LS(-72.14)R 12 3 946.08752 -0.21264 318770 0 0 0 0 0 0 318770 283 240 88 88 5650 6436 55166 33762 Mix4_TiO2_Reinj_1_5 5634 55167 33763 Mix4_TiO2_Reinj_1_5 5639 O95155;O95155-2 O95155 O95155 >sp|O95155|UBE4B_HUMAN Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B PE=1 SV=1;>sp|O95155-2|UBE4B_HUMAN Isoform 2 of Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B 0.940234 12.4932 0.773974 6.83334 0.00537083 75.972 0.940234 12.4932 7.46656E-26 163.5 0 0 0.78912 6.17845 0.000260404 80.734 0.0431831 -13.078 0.000177763 86.481 1 S VSSLSSSPSNSLE CK1;GSK3;NEK6;Polo box;Proline-directed 0.00405 7.46656E-26 163.5 _SQSSEGVSSLSSpSPSNSLETQSQSLSR_ SQSSEGVSSLSS(0.002)S(0.94)PS(0.053)NS(0.004)LETQSQSLSR S(-61.1)QS(-60.63)S(-60.63)EGVS(-67.32)S(-68.16)LS(-45.66)S(-26.09)S(12.49)PS(-12.49)NS(-23.68)LET(-33.71)QS(-45)QS(-53.94)LS(-53.94)R 13 2 1418.6276 -0.53982 692580 71609 0 0 323510 0 297460 0 284 240 90 90 5650 6436 55167 33763 Mix4_TiO2_Reinj_1_5 5639 55167 33763 Mix4_TiO2_Reinj_1_5 5639 O95155;O95155-2 O95155 O95155 >sp|O95155|UBE4B_HUMAN Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B PE=1 SV=1;>sp|O95155-2|UBE4B_HUMAN Isoform 2 of Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B 0.817952 7.28632 0.160469 -6.83334 0.00537083 75.972 0.817952 7.28632 7.46656E-26 163.5 0 0 0.190238 -6.17845 0.000260404 80.734 0.00239706 -25.6343 0.000177763 86.481 1 S SLSSSPSNSLETQ CK1 0.081 7.46656E-26 163.5 _SQSSEGVSSLSSSPpSNSLETQSQSLSR_ SQSSEGVSSLSSS(0.153)PS(0.818)NS(0.029)LETQSQSLSR S(-111.16)QS(-110.54)S(-108.72)EGVS(-64.82)S(-57.18)LS(-42.55)S(-36.89)S(-7.29)PS(7.29)NS(-14.5)LET(-49.35)QS(-62.68)QS(-82.88)LS(-102.16)R 15 3 946.08752 -0.070819 1532800 0 0 0 1532800 0 0 0 285 240 803 803 6277 7172 62751 38172 Mix4_TiO2_Reinj_1_5 5201 62751 38172 Mix4_TiO2_Reinj_1_5 5201 O95155;O95155-2;O95155-3 O95155 O95155 >sp|O95155|UBE4B_HUMAN Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B PE=1 SV=1;>sp|O95155-2|UBE4B_HUMAN Isoform 2 of Ubiquitin conjugation factor E4 B OS=Homo sapiens GN=UBE4B;>sp|O95155-3|UBE4B_HUMAN Isoform 3 of Ubiquitin conjugation factor 0.999974 46.085 0.993312 22.6476 0.011244 67.562 0.999974 46.085 3.57731E-11 134.28 1 S ESQWKDSPLATRH Proline-directed 0.05 3.57731E-11 134.28 _TVEDLKNNESQWKDpSPLATR_ TVEDLKNNESQWKDS(1)PLATR T(-127.51)VEDLKNNES(-57.42)QWKDS(46.08)PLAT(-46.08)R 15 3 804.37947 0.52706 439510 89445 0 0 350070 0 0 0 286 242 30 30 177 205 1894 1272 Mix4_TiO2_Reinj_1_6 5054 1894 1272 Mix4_TiO2_Reinj_1_6 5054 O95197;O95197-2;O95197-4;O95197-5;O95197-3 O95197 O95197 >sp|O95197|RTN3_HUMAN Reticulon-3 OS=Homo sapiens GN=RTN3 PE=1 SV=2;>sp|O95197-2|RTN3_HUMAN Isoform A3b of Reticulon-3 OS=Homo sapiens GN=RTN3;>sp|O95197-4|RTN3_HUMAN Isoform A2 of Reticulon-3 OS=Homo sapiens GN=RTN3;>sp|O95197-5|RTN3_HUMAN Isoform 5 of Re 0.990262 21.6246 0.941384 12.9386 0.749592 56.084 0.990262 21.6246 1.6584E-06 107.16 1 S APGGGGSPGACPA Proline-directed 0.05 1.6584E-06 107.16 _(ac)AEPSAATQSHSISSSSFGAEPSAPGGGGpSPGACPALGTK_ AEPSAATQSHSISSSSFGAEPS(0.007)APGGGGS(0.99)PGACPALGT(0.003)K AEPS(-103.01)AAT(-101.61)QS(-101.61)HS(-101.61)IS(-94.07)S(-87.59)S(-81.45)S(-74.08)FGAEPS(-21.62)APGGGGS(21.62)PGACPALGT(-25.3)K 29 4 923.90972 0.019875 516630 11.643 105290 0 0 411340 0 0 0 287 243 153 153 1901 2149 17505 10500 Mix4_TiO2_Reinj_1_4 3556 17505 10500 Mix4_TiO2_Reinj_1_4 3556 O95218;O95218-2 O95218 O95218 >sp|O95218|ZRAB2_HUMAN Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens GN=ZRANB2 PE=1 SV=2;>sp|O95218-2|ZRAB2_HUMAN Isoform ZIS-2 of Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens GN=ZRANB2 1 120.894 1 66.5991 0.0120919 66.599 1 120.894 1.89656E-10 120.89 1 S EVEDKESEGEEED CK2 0.117 1.89656E-10 120.89 _EVEDKEpSEGEEEDEDEDLSK_ EVEDKES(1)EGEEEDEDEDLSK EVEDKES(120.89)EGEEEDEDEDLS(-120.89)K 7 3 807.30592 0.9776 239090 112920 0 0 126170 0 0 0 288 245 210 210 1361 1532 12822 7909 Mix4_TiO2_Reinj_1_2 3784 12822 7909 Mix4_TiO2_Reinj_1_2 3784 O95297;O95297-2;O95297-4 O95297 O95297 >sp|O95297|MPZL1_HUMAN Myelin protein zero-like protein 1 OS=Homo sapiens GN=MPZL1 PE=1 SV=1;>sp|O95297-2|MPZL1_HUMAN Isoform PZR1a of Myelin protein zero-like protein 1 OS=Homo sapiens GN=MPZL1;>sp|O95297-4|MPZL1_HUMAN Isoform MPZL1b of Myelin protein zer 0.997553 29.1277 0 0 0.997553 29.1277 0.0138278 69.974 1 S STSESLSPVKQAP CDK1;CDK2;CK1;Proline-directed 0.0057 0.0138278 69.974 _DYTGCSTSESLpSPVK_ DYTGCSTS(0.001)ES(0.001)LS(0.998)PVK DY(-69.97)T(-67.84)GCS(-42.73)T(-36)S(-29.13)ES(-30.34)LS(29.13)PVK 12 2 855.85005 -0.20293 29086 0 0 0 29086 0 0 0 289 247 337 337 213 245 2166 1420 Mix4_TiO2_Reinj_1_3 1970 2166 1420 Mix4_TiO2_Reinj_1_3 1970 O95365 O95365 O95365 >sp|O95365|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A OS=Homo sapiens GN=ZBTB7A PE=1 SV=1 0.998972 29.8744 0 0 0.998972 29.8744 0.00427768 77.586 1 S GAAAGDSDEESRA CK2;GSK3 0.081 0.00427768 77.586 _AGAAAGDpSDEESRADDK_ AGAAAGDS(0.999)DEES(0.001)RADDK AGAAAGDS(29.87)DEES(-29.87)RADDK 8 2 872.83652 -0.19453 44880 0 0 0 44880 0 0 0 290 247 525 525 2198 2490 20171 12403 Mix4_TiO2_Reinj_1_3 3845 20171 12403 Mix4_TiO2_Reinj_1_3 3845 O95365 O95365 O95365 >sp|O95365|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A OS=Homo sapiens GN=ZBTB7A PE=1 SV=1 0.5 0 0 0 0.5 0 9.26599E-05 93.633 1 S GAPAQPSSPDARR CK2 0.117 9.26599E-05 93.633 _GGAPDPSPGATATPGAPAQPpSSPDAR_ GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR GGAPDPS(-93.63)PGAT(-93.63)AT(-92.52)PGAPAQPS(0)S(0)PDAR 21 3 804.02721 1.0023 368780 0.8883 0 0 0 368780 0 0 0 291 247 526 526 2198 2490 20171 12403 Mix4_TiO2_Reinj_1_3 3845 20171 12403 Mix4_TiO2_Reinj_1_3 3845 O95365 O95365 O95365 >sp|O95365|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A OS=Homo sapiens GN=ZBTB7A PE=1 SV=1 0.5 0 0 0 0.5 0 9.26599E-05 93.633 1 S APAQPSSPDARRN ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 9.26599E-05 93.633 _GGAPDPSPGATATPGAPAQPpSSPDAR_ GGAPDPSPGATATPGAPAQPS(0.5)S(0.5)PDAR GGAPDPS(-93.63)PGAT(-93.63)AT(-92.52)PGAPAQPS(0)S(0)PDAR 22 3 804.02721 1.0023 368780 0.8883 0 0 0 368780 0 0 0 292 249 964 964 674 775 6477 3847 Mix4_TiO2_Reinj_1_5 4982 6477 3847 Mix4_TiO2_Reinj_1_5 4982 O95382;O95382-3;O95382-2 O95382 O95382 >sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens GN=MAP3K6 PE=1 SV=3;>sp|O95382-3|M3K6_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens GN=MAP3K6;>sp|O95382-2|M3K6_HUMAN Isoform 2 of 0.997863 27.6816 0.974637 15.8955 0.0594012 45.847 0.997863 27.6816 0.0480867 49.202 1 S PPKRCLSYGGTSQ CAMK2;PKA 0.003024 0.0480867 49.202 _CLpSYGGTSQLR_ CLS(0.998)Y(0.002)GGTSQLR CLS(27.68)Y(-27.68)GGT(-34.19)S(-42.57)QLR 3 2 661.28395 0.53145 108500 30753 0 0 77747 0 0 0 293 249 957 957 4438 5048 42231 25997 Mix4_TiO2_Reinj_1_5 4845 42231 25997 Mix4_TiO2_Reinj_1_5 4845 O95382;O95382-3;O95382-2 O95382 O95382 >sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens GN=MAP3K6 PE=1 SV=3;>sp|O95382-3|M3K6_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens GN=MAP3K6;>sp|O95382-2|M3K6_HUMAN Isoform 2 of 0.995874 23.8326 0.953222 14.1944 0.0170455 78.832 0.995874 23.8326 0.000589893 95.46 1 S PSQHPPSPPKRCL CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000589893 95.46 _PSDAPSASPTPSANSTTQSQTFPCPQAPSQHPPpSPPKR_ PSDAPSASPTPSANSTTQSQTFPCPQAPS(0.004)QHPPS(0.996)PPKR PS(-83.43)DAPS(-82.05)AS(-79.83)PT(-77.05)PS(-72.97)ANS(-70.38)T(-70.38)T(-67.13)QS(-64.1)QT(-53.36)FPCPQAPS(-23.83)QHPPS(23.83)PPKR 34 4 1005.96 -0.85848 487510 83040 0 0 404470 0 0 0 294 249 984 984 6523 7463 65902 40415 Mix4_TiO2_1_5 5595 65902 40415 Mix4_TiO2_1_5 5595 O95382;O95382-3;O95382-2 O95382 O95382 >sp|O95382|M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens GN=MAP3K6 PE=1 SV=3;>sp|O95382-3|M3K6_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens GN=MAP3K6;>sp|O95382-2|M3K6_HUMAN Isoform 2 of 0.999959 45.5448 0.999959 45.5448 4.40204E-12 127.18 0.976651 17.7609 0.000180288 86.306 1 S AAEEPASPEESSG CK2;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 4.40204E-12 127.18 _VPEEPAAEEPApSPEESSGLSLLHQESK_ VPEEPAAEEPAS(1)PEESSGLSLLHQESK VPEEPAAEEPAS(45.54)PEES(-49.74)S(-45.54)GLS(-55.23)LLHQES(-94.82)K 12 3 976.44465 -0.15794 1414900 7.7474 361920 0 0 1052900 0 0 0 295 250 215 215 3786 4278 35963 22260 Mix4_TiO2_Reinj_1_5 2251 35962 22258 Mix4_TiO2_Reinj_1_3 2127 O95391 O95391 O95391 >sp|O95391|SLU7_HUMAN Pre-mRNA-splicing factor SLU7 OS=Homo sapiens GN=SLU7 PE=1 SV=2 1 40.7938 1 40.7938 0.0714813 40.794 1 23.0954 0.319606 23.095 1 40.7938 0.00681582 64.131 1 S LVEQANSPKHQWG CDK1;Proline-directed 0.0057 0.00681582 64.131 _LVEQANpSPK_ LVEQANS(1)PK LVEQANS(40.79)PK 7 2 533.25245 0.97942 276260 33146 10243 0 232870 0 0 0 296 251 245 245 1247 1403 11704 7187 Mix4_TiO2_Reinj_1_1 3689 11704 7187 Mix4_TiO2_Reinj_1_1 3689 O95425;O95425-2 O95425 O95425 >sp|O95425|SVIL_HUMAN Supervillin OS=Homo sapiens GN=SVIL PE=1 SV=2;>sp|O95425-2|SVIL_HUMAN Isoform p205 of Supervillin OS=Homo sapiens GN=SVIL 0.999965 49.275 0.993843 26.851 0.259395 26.851 0 0 0.999965 49.275 0.0559069 49.275 0 0 0 0 1 S FTEVPRSPKHAHS CDK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0559069 49.275 _DSSFTEVPRpSPK_ DSSFTEVPRS(1)PK DS(-49.27)S(-49.27)FT(-49.27)EVPRS(49.27)PK 10 2 715.32159 -0.1724 254050 43218 0 0 210830 0 0 0 297 252 176 176 5711 6508 56094 34315 Mix4_TiO2_1_3 1459 56092 34311 Mix4_InSol_TiO2_1 2166 O95429 O95429 O95429 >sp|O95429|BAG4_HUMAN BAG family molecular chaperone regulator 4 OS=Homo sapiens GN=BAG4 PE=1 SV=1 0.455724 1.55095 0.455724 1.55095 0.0552436 47.08 0.0155741 -15.8218 0.0211426 57.193 0.258347 -1.55516 0.00937969 63.945 0.166656 -4.67314 0.149761 34.63 1 S PSTYRSSGNSPTP CK1;PKA 0.042 0.00937969 63.945 _SpSGNSPTPVSR_ S(0.319)S(0.456)GNS(0.11)PT(0.116)PVSR S(-1.55)S(1.55)GNS(-6.18)PT(-5.96)PVS(-47.08)R 2 2 584.75334 -0.56544 0 0 0 0 0 0 0 0 298 252 179 179 5711 6508 56096 34318 Mix4_TiO2_Reinj_1_3 2067 56092 34311 Mix4_InSol_TiO2_1 2166 O95429 O95429 O95429 >sp|O95429|BAG4_HUMAN BAG family molecular chaperone regulator 4 OS=Homo sapiens GN=BAG4 PE=1 SV=1 0.595098 1.96476 0.312163 -2.75277 0.0552436 47.08 0.595098 1.96476 0.0211426 57.193 0.369589 1.55516 0.00937969 63.945 0.224389 -3.38134 0.149761 34.63 1 S YRSSGNSPTPVSR CK1;Proline-directed 0.05 0.00937969 63.945 _SSGNpSPTPVSR_ S(0.011)S(0.016)GNS(0.595)PT(0.379)PVSR S(-17.42)S(-15.82)GNS(1.96)PT(-1.96)PVS(-57.19)R 5 2 584.75334 0.77669 197180 0 0 0 197180 0 0 0 299 253 1031 1031 1364;2175 1535;2463 20005 12319 Mix4_TiO2_Reinj_1_5 2573 12832 7922 Mix4_TiO2_Reinj_1_5 3538 O95466-2;O95466 O95466-2 O95466-2 >sp|O95466-2|FMNL_HUMAN Isoform 2 of Formin-like protein 1 OS=Homo sapiens GN=FMNL1;>sp|O95466|FMNL_HUMAN Formin-like protein 1 OS=Homo sapiens GN=FMNL1 PE=1 SV=3 1 35.6285 1 74.328 3.133E-12 134.22 0.999966 44.6311 0.0342897 59.687 1 35.6285 2.19259E-13 137.17 0 0 0 0 0.999993 51.4127 0.00296379 77.33 1 S EPPAPKSPPKARR CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.19259E-13 137.17 _GEPPAPKpSPPK_ GEPPAPKS(1)PPK GEPPAPKS(35.63)PPK 8 2 592.7892 0.29002 7480200 1389200 80644 0 5933600 0 0 76763 300 253 184 184 4104;4105 4673;4674 38848 23825 Mix4_TiO2_1_5 4168 38852 23830 Mix4_TiO2_Reinj_1_5 4909 O95466-2;O95466 O95466-2 O95466-2 >sp|O95466-2|FMNL_HUMAN Isoform 2 of Formin-like protein 1 OS=Homo sapiens GN=FMNL1;>sp|O95466|FMNL_HUMAN Formin-like protein 1 OS=Homo sapiens GN=FMNL1 PE=1 SV=3 1 73.5624 1 73.5624 3.77418E-05 123.75 0.94106 12.0321 0.083893 37.086 0.999999 59.1064 3.26881E-06 145.3 0.999986 51.8999 0.012368 65.675 0.958757 13.7725 0.0421041 57.753 1 S NKPLEQSVEDLSK CK2;NEK6;PLK;PLK1 0.0027378 3.26881E-06 145.3 _NKPLEQpSVEDLSK_ NKPLEQS(1)VEDLSK NKPLEQS(73.56)VEDLS(-73.56)K 7 2 783.87419 -0.092035 2610900 458680 0 0 1505200 0 338660 308420 301 253 624 624 4834 5488 46155 28225 Mix4_TiO2_Reinj_1_5 3320 46155 28225 Mix4_TiO2_Reinj_1_5 3320 O95466-2;O95466 O95466-2 O95466-2 >sp|O95466-2|FMNL_HUMAN Isoform 2 of Formin-like protein 1 OS=Homo sapiens GN=FMNL1;>sp|O95466|FMNL_HUMAN Formin-like protein 1 OS=Homo sapiens GN=FMNL1 PE=1 SV=3 1 44.786 1 25.3559 0.253465 25.356 0 0 1 44.786 0.0536704 44.786 0 0 1 4.34946 0.698999 4.3495 1 S ALGRRDSELGPGV CAMK2;CHK1;CHK1/2;PKA;PKD 0.003192 0.0536704 44.786 _RDpSELGPGVK_ RDS(1)ELGPGVK RDS(44.79)ELGPGVK 3 2 569.26863 0.20939 1257700 149430 0 0 1078400 0 0 29952 302 254 1224 1224 1243 1399 11673 7178 Mix4_TiO2_Reinj_1_5 7625 11673 7178 Mix4_TiO2_Reinj_1_5 7625 O95487;O95487-2 O95487 O95487 >sp|O95487|SC24B_HUMAN Protein transport protein Sec24B OS=Homo sapiens GN=SEC24B PE=1 SV=2;>sp|O95487-2|SC24B_HUMAN Isoform 2 of Protein transport protein Sec24B OS=Homo sapiens GN=SEC24B 0.895375 9.32399 0 0 0.895375 9.32399 0.0970366 50.844 1 S RDSRPLSPILHIV CAMK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0970366 50.844 _DSRPLpSPILHIVKDESPAK_ DS(0.105)RPLS(0.895)PILHIVKDESPAK DS(-9.32)RPLS(9.32)PILHIVKDES(-50.84)PAK 6 3 728.0471 -0.079201 97514 0 0 0 97514 0 0 0 303 257 239 239 2571 2922 24112 14961 Mix4_TiO2_Reinj_1_3 6729 24112 14961 Mix4_TiO2_Reinj_1_3 6729 O95671;O95671-2 O95671 O95671 >sp|O95671|ASML_HUMAN N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens GN=ASMTL PE=1 SV=3;>sp|O95671-2|ASML_HUMAN Isoform 2 of N-acetylserotonin O-methyltransferase-like protein OS=Homo sapiens GN=ASMTL 0.999567 33.7009 0.944513 12.3506 2.05311E-07 108.14 0.999567 33.7009 9.10124E-18 137.94 1 S DTFEDLSDVEGGG CK2 0.117 9.10124E-18 137.94 _HDSIPAADTFEDLpSDVEGGGSEPTQR_ HDSIPAADTFEDLS(1)DVEGGGSEPTQR HDS(-51.87)IPAADT(-33.7)FEDLS(33.7)DVEGGGS(-89.06)EPT(-115.7)QR 14 3 937.39781 -0.4375 1466300 0.93884 366420 0 0 1099900 0 0 0 304 258 21 21 1810;6333;6334 2042;7240;7241;7242 63801 39114 Mix4_TiO2_Reinj_1_4 3843 63801 39114 Mix4_TiO2_Reinj_1_4 3843 O95674 O95674 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 2 OS=Homo sapiens GN=CDS2 PE=1 SV=1 0.998144 27.3146 0.996119 24.0934 0.010878 69.808 0 0 0.998144 27.3146 7.47166E-08 107.06 0.486465 0 1.39444 33.285 0 0 1 S PPEDKESESEAKV CK2 0.117 7.47166E-08 107.06 _VAHEPVAPPEDKEpSESEAKVDGETASDSESR_ VAHEPVAPPEDKES(0.998)ES(0.002)EAKVDGETASDSESR VAHEPVAPPEDKES(27.31)ES(-27.31)EAKVDGET(-55.59)AS(-65.41)DS(-69.64)ES(-75.45)R 14 3 1121.4896 -0.022421 2020100 0.74289 383950 0 0 1636200 0 0 0 305 258 23 23 1810;6333;6334 2042;7240;7241;7242 63783 39108 Mix4_TiO2_Reinj_1_5 3349 63801 39114 Mix4_TiO2_Reinj_1_4 3843 O95674 O95674 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 2 OS=Homo sapiens GN=CDS2 PE=1 SV=1 0.845489 7.38148 0.530668 0.436408 0.749536 46.866 0 0 0.845489 7.38148 7.47166E-08 107.06 0.486465 0 1.39444 33.285 0 0 1 S EDKESESEAKVDG 7.47166E-08 107.06 _VAHEPVAPPEDKESEpSEAK_ VAHEPVAPPEDKES(0.155)ES(0.845)EAK VAHEPVAPPEDKES(-7.38)ES(7.38)EAK 16 2 1064.9754 -0.43439 223070 0.082031 115570 0 0 107500 0 0 0 306 258 33 33 1810;6334;6361;6362 2042;7241;7242;7276;7278 64210 39400 Mix4_TiO2_Reinj_1_1 1478 64210 39400 Mix4_TiO2_Reinj_1_1 1478 O95674 O95674 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 2 OS=Homo sapiens GN=CDS2 PE=1 SV=1 0.999273 31.3878 0.999215 31.0481 1.269E-05 139.29 0 0 0.999273 31.3878 5.55317E-06 149.07 0 0 0.00318654 -21.8373 1.39444 33.285 0 0 1 S VDGETASDSESRA CK2;GSK3 0.081 5.55317E-06 149.07 _VDGETApSDSESR_ VDGETAS(0.999)DS(0.001)ESR VDGET(-63.37)AS(31.39)DS(-31.39)ES(-70.47)R 7 2 666.75119 0.087848 7048800 2.5028 710220 0 0 6338500 0 0 0 307 258 35 35 1810;6334;6361;6362 2042;7241;7242;7276;7278 64232 39411 Mix4_TiO2_1_3 5655 64210 39400 Mix4_TiO2_Reinj_1_1 1478 O95674 O95674 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 2 OS=Homo sapiens GN=CDS2 PE=1 SV=1 0.448412 0 0.448412 0 1.269E-05 139.29 0 0 0.162474 -6.76841 5.55317E-06 149.07 0 0 0.00140912 -25.381 1.39444 33.285 0 0 1 S GETASDSESRAES CK1 0.143 5.55317E-06 149.07 _VDGETApSDSESRAESAPLPVSADDTPEVLNR_ VDGET(0.026)AS(0.448)DS(0.448)ES(0.077)RAESAPLPVSADDTPEVLNR VDGET(-12.43)AS(0)DS(0)ES(-7.63)RAES(-32.86)APLPVS(-95.27)ADDT(-112.11)PEVLNR 9 3 1098.8264 0.047047 0 0 0 0 0 0 0 0 0 308 258 37 37 1810;6334;6361;6362 2042;7241;7242;7276;7278 64233 39412 Mix4_TiO2_1_4 5639 64210 39400 Mix4_TiO2_Reinj_1_1 1478 O95674 O95674 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 2 OS=Homo sapiens GN=CDS2 PE=1 SV=1 0.325291 0 0.325291 0 1.269E-05 139.29 0 0 0.0493018 -9.3526 5.55317E-06 149.07 0 0 0.000676834 -28.5657 1.39444 33.285 0 0 1 S TASDSESRAESAP CK1;CK2;GSK3 0.081 5.55317E-06 149.07 _VDGETApSDSESRAESAPLPVSADDTPEVLNR_ VDGET(0.003)AS(0.325)DS(0.325)ES(0.325)RAES(0.021)APLPVSADDTPEVLNR VDGET(-20.22)AS(0)DS(0)ES(0)RAES(-11.89)APLPVS(-85.55)ADDT(-100.88)PEVLNR 11 3 1098.8264 0.39815 0 0 0 0 0 0 0 0 0 309 259 361 361 3135;4206 3560;4792 29805 18557 Mix4_TiO2_1_4 3025 40140 24775 Mix4_TiO2_1_3 3262 O95677;O95677-4;O95677-2;O95677-3 O95677 O95677 >sp|O95677|EYA4_HUMAN Eyes absent homolog 4 OS=Homo sapiens GN=EYA4 PE=1 SV=2;>sp|O95677-4|EYA4_HUMAN Isoform 4 of Eyes absent homolog 4 OS=Homo sapiens GN=EYA4;>sp|O95677-2|EYA4_HUMAN Isoform 2 of Eyes absent homolog 4 OS=Homo sapiens GN=EYA4;>sp|O95677-3 0.999999 62.1466 0.999999 62.1466 0.00338656 85.813 0.999955 43.4832 0.0159529 66.187 0 0 0 0 1 S GRKNNPSPPPDSD Proline-directed 0.05 0.00338656 85.813 _KNNPpSPPPDSDLER_ KNNPS(1)PPPDSDLER KNNPS(62.15)PPPDS(-62.15)DLER 5 2 823.36452 3.014 767310 184750 0 0 582560 0 0 0 310 261 2928 2928 2896 3299 27735 17286 Mix4_TiO2_Reinj_1_1 7086 27735 17286 Mix4_TiO2_Reinj_1_1 7086 O95714 O95714 O95714 >sp|O95714|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens GN=HERC2 PE=1 SV=2 1 73.9912 0.998711 31.9038 0.0527933 67.431 0 0 1 73.9912 1.88149E-08 116.02 0 0 1 S AVPFLASDNEEEE CK2 0.117 1.88149E-08 116.02 _IRAEEEDLAAVPFLApSDNEEEEDEKGNSGSLIR_ IRAEEEDLAAVPFLAS(1)DNEEEEDEKGNSGSLIR IRAEEEDLAAVPFLAS(73.99)DNEEEEDEKGNS(-73.99)GS(-78.78)LIR 16 3 1238.2336 0.28159 655600 121080 0 0 534530 0 0 0 311 262 339 339 5958 6795 58840 35716 Mix4_TiO2_Reinj_1_4 7337 58840 35716 Mix4_TiO2_Reinj_1_4 7337 O95747 O95747 O95747 >sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 OS=Homo sapiens GN=OXSR1 PE=1 SV=1 1 101.21 1 77.8502 1.12713E-23 161.5 1 101.21 2.20834E-32 184.6 1 S DGGWEWSDDEFDE CK2 0.117 2.20834E-32 184.6 _TEDGGWEWpSDDEFDEESEEGK_ TEDGGWEWS(1)DDEFDEESEEGK T(-118.02)EDGGWEWS(101.21)DDEFDEES(-101.21)EEGK 9 2 1278.4478 0.81059 2378100 810390 0 0 1567700 0 0 0 312 263 1054 1054 476 540 4462 2683 Mix4_TiO2_Reinj_1_5 5590 4462 2683 Mix4_TiO2_Reinj_1_5 5590 O95759;O95759-2 O95759 O95759 >sp|O95759|TBCD8_HUMAN TBC1 domain family member 8 OS=Homo sapiens GN=TBC1D8 PE=1 SV=3;>sp|O95759-2|TBCD8_HUMAN Isoform 2 of TBC1 domain family member 8 OS=Homo sapiens GN=TBC1D8 0.954802 13.2582 0 0 0.954802 13.2582 0.0134699 70.247 1 S LRASAPSPEDSVF CK1;CK2;GSK3;Proline-directed 0.05 0.0134699 70.247 _ASAPpSPEDSVFADTGK_ ASAPS(0.955)PEDS(0.045)VFADTGK AS(-39.54)APS(13.26)PEDS(-13.26)VFADT(-64.49)GK 5 2 829.85091 0.072363 209370 0 0 0 209370 0 0 0 313 264 193 193 3547 4001 33486 20643 Mix4_TiO2_Reinj_1_2 4703 33486 20643 Mix4_TiO2_Reinj_1_2 4703 O95772;O95772-2 O95772 O95772 >sp|O95772|MENTO_HUMAN MLN64 N-terminal domain homolog OS=Homo sapiens GN=STARD3NL PE=1 SV=1;>sp|O95772-2|MENTO_HUMAN Isoform 2 of MLN64 N-terminal domain homolog OS=Homo sapiens GN=STARD3NL 1 105.3 1 70.9767 0.00352756 70.977 1 105.3 0.00294485 105.3 0 0 0 0 1 S LIVQDASERAALI 0.00294485 105.3 _LLIVQDApSER_ LLIVQDAS(1)ER LLIVQDAS(105.3)ER 8 2 612.30521 0.16081 79384 17627 0 0 61757 0 0 0 314 265 173 173 5649 6435 55160 33758 Mix4_InSol_Tio2_Reinj_1 3539 55160 33758 Mix4_InSol_Tio2_Reinj_1 3539 O95817 O95817 O95817 >sp|O95817|BAG3_HUMAN BAG family molecular chaperone regulator 3 OS=Homo sapiens GN=BAG3 PE=1 SV=3 0.565069 1.13748 0 0 0.555043 0.977741 0.000240705 91.639 0.565069 1.13748 6.09143E-13 137.07 1 S GPERSQSPAASDC CAMK2;GSK3;Proline-directed 0.042 6.09143E-13 137.07 _SQpSPAASDCSSSSSSASLPSSGR_ S(0.435)QS(0.565)PAASDCSSSSSSASLPSSGR S(-1.14)QS(1.14)PAAS(-39.32)DCS(-80.95)S(-94.19)S(-100.18)S(-112.27)S(-117.36)S(-131.62)AS(-137.07)LPS(-137.07)S(-137.07)GR 3 2 1140.4577 0.27422 178120 0 0 0 0 0 98696 79425 315 265 275 275 5767 6572 56775 34637 Mix4_TiO2_Reinj_1_3 1892 56775 34637 Mix4_TiO2_Reinj_1_3 1892 O95817 O95817 O95817 >sp|O95817|BAG3_HUMAN BAG family molecular chaperone regulator 3 OS=Homo sapiens GN=BAG3 PE=1 SV=3 0.98612 18.5424 0.98612 18.5424 0.0166984 67.459 0.694262 6.22255 0.92059 12.639 0.467361 3.55005 1.23508 3.5501 2 S SVQGASSREGSPA GSK3 0.081 0.0166984 67.459 _SSVQGASpSREGpSPAR_ SSVQGAS(0.014)S(0.986)REGS(1)PAR S(-44.1)S(-43.12)VQGAS(-18.54)S(18.54)REGS(41.94)PAR 8 2 818.32982 -0.72125 178430 0 0 0 110580 0 67849 0 316 265 279 279 5767 6572 56775 34637 Mix4_TiO2_Reinj_1_3 1892 56775 34637 Mix4_TiO2_Reinj_1_3 1892 O95817 O95817 O95817 >sp|O95817|BAG3_HUMAN BAG family molecular chaperone regulator 3 OS=Homo sapiens GN=BAG3 PE=1 SV=3 0.999936 41.9373 0.999936 41.9373 0.0166984 67.459 0.805003 12.6393 0.92059 12.639 0.467361 3.55005 1.23508 3.5501 2 S ASSREGSPARSST CAMK2;CDK1;CDK2;CK1;GSK3;Proline-directed 0.0057 0.0166984 67.459 _SSVQGASpSREGpSPAR_ SSVQGAS(0.014)S(0.986)REGS(1)PAR S(-44.1)S(-43.12)VQGAS(-18.54)S(18.54)REGS(41.94)PAR 12 2 818.32982 -0.72125 178430 0 0 0 110580 0 67849 0 317 266 885 885 81 96 932 611 Mix4_InSol_Tio2_Reinj_1 4954 932 611 Mix4_InSol_Tio2_Reinj_1 4954 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.999998 56.4407 0 0 0 0 0 0 0 0 0.999895 39.7711 7.13812E-13 153.03 0.999998 56.4407 8.02838E-20 178.6 1 S ASSLNLSNGETES CK1;CK2;NEK6 0.076 8.02838E-20 178.6 _AASSLNLpSNGETESVK_ AASSLNLS(1)NGETESVK AAS(-101.8)S(-101.8)LNLS(56.44)NGET(-56.44)ES(-97.37)VK 8 2 843.88274 0.95271 1030800 0 0 0 0 0 478040 552760 318 266 716 716 1239;4844 1395;5504 46347 28338 Mix4_InSol_Tio2_Reinj_1 2697 46354 28346 Mix4_TiO2_Reinj_1_5 2509 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 1 75.0104 0.996658 24.7531 0.00071496 90.167 0.972373 15.727 0.607274 27.788 0.999995 53.0631 7.08986E-10 122.09 1 74.3304 3.40714E-06 108.56 1 75.0104 2.38615E-06 111.4 1 S VLSRRDSPLQGSG CAMK2;CHK1;CHK1/2;CK1;PKA;PKD;Proline-directed 0.003192 7.08986E-10 122.09 _RDpSPLQGSGQQNSQAGQR_ RDS(1)PLQGSGQQNSQAGQR RDS(75.01)PLQGS(-75.01)GQQNS(-91.99)QAGQR 3 2 997.44542 0.64328 4200300 4.5648 568510 12246 0 2119700 0 928360 571460 319 266 733 733 1239 1395 11651 7163 Mix4_InSol_Tio2_Reinj_1 4361 11651 7163 Mix4_InSol_Tio2_Reinj_1 4361 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.773801 6.29579 0 0 0 0 0 0 0.773801 6.29579 0.0194293 62.804 1 S QAGQRNSTSIEPR PKA 0.042 0.0194293 62.804 _DSPLQGSGQQNSQAGQRNpSTSIEPR_ DSPLQGSGQQNS(0.001)QAGQRNS(0.774)T(0.182)S(0.044)IEPR DS(-62.62)PLQGS(-44.94)GQQNS(-31.81)QAGQRNS(6.3)T(-6.3)S(-12.44)IEPR 19 3 908.0774 -0.64451 68796 0 0 0 0 0 0 68796 320 266 980 980 3051 3471 29118 18206 Mix4_TiO2_1_5 4112 29118 18206 Mix4_TiO2_1_5 4112 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.999994 57.1475 0.999994 57.1475 0.0107795 68.049 0 0 0.999707 38.2217 0.143582 49.115 0 0 0 0 1 S DPTRKGSVVNVNP AURORA;AURORA-1;AURORA-A;CAMK2;CK1;PKA 0.002856 0.0107795 68.049 _KGpSVVNVNPTNTRPQSDTPEIR_ KGS(1)VVNVNPTNTRPQSDTPEIR KGS(57.15)VVNVNPT(-57.15)NT(-57.15)RPQS(-57.48)DT(-64.12)PEIR 3 3 830.40965 -0.31187 1675500 505000 0 0 1170500 0 0 0 321 266 580 580 3239;6110 3671;6974 60384 36528 Mix4_InSol_TiO2_1 1008 60384 36528 Mix4_InSol_TiO2_1 1008 O95819-3;O95819;O95819-2 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4 PE=1 SV=2;>sp|O95819-2|M4K4_HUMAN 0.997028 25.2559 0.997028 25.2559 0.000160465 143.63 0.944168 12.2817 0.0032567 118.72 1 S RKTNHSSPEAQSK CK1;Polo box;Proline-directed 0.00405 0.000160465 143.63 _TNHSpSPEAQSK_ TNHS(0.003)S(0.997)PEAQSK T(-87.74)NHS(-25.26)S(25.26)PEAQS(-103.04)K 5 2 633.26153 -0.049565 327050 0 0 0 0 0 151330 175710 322 266;1237;1772 175;175;175 175 3783 4275 35922 22243 Mix4_TiO2_Reinj_1_2 5833 35924 22246 Mix4_TiO2_Reinj_1_5 6708 O95819-3;O95819-5;O95819;O95819-2;O95819-4;Q8N4C8;Q8N4C8-3;Q8N4C8-2;Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 O95819-3;Q8N4C8;Q9UKE5 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.850402 7.54697 0 0 0.850402 7.54697 0.0167682 67.465 0 0 0 0 0 0 1 S LVDFGVSAQLDRT 0.0167682 67.465 _LVDFGVpSAQLDRTVGR_ LVDFGVS(0.85)AQLDRT(0.15)VGR LVDFGVS(7.55)AQLDRT(-7.55)VGR 7 3 604.97165 0.18579 39932 0 0 0 39932 0 0 0 323 266 769 769 3794;4418 4287;5026 42076 25923 Mix4_TiO2_Reinj_1_1 1481 36027 22301 Mix4_TiO2_Reinj_1_5 2920 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.332676 0.628691 0.000917748 -29.5134 1.44683 29.893 0 0 0.332676 0.628691 0.000405827 81.65 0.331067 0.972338 1.52188 32.5 0.288589 -0.384912 1.01586 44.302 1 S SGSQPGSHPGSQS CK1;GSK3 0.081 0.000405827 81.65 _PGSGSSSGSSNSGSQPGpSHPGSQSGSGER_ PGSGSSSGS(0.003)S(0.003)NS(0.003)GS(0.003)QPGS(0.333)HPGS(0.288)QS(0.288)GS(0.081)GER PGS(-35.72)GS(-37.21)S(-35.82)S(-31.24)GS(-21.11)S(-21.11)NS(-21.11)GS(-21.11)QPGS(0.63)HPGS(-0.63)QS(-0.63)GS(-6.14)GER 18 3 895.02526 -0.052284 0 0 0 0 0 0 0 0 0 324 266 773 773 3794;4418 4287;5026 36028 22303 Mix4_TiO2_Reinj_1_5 2982 36027 22301 Mix4_TiO2_Reinj_1_5 2920 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.318057 0 0.0873507 -9.72794 1.44683 29.893 0 0 0.318057 0 0.000405827 81.65 0.264656 -0.972338 1.52188 32.5 0.315334 0.384912 1.01586 44.302 1 S PGSHPGSQSGSGE CK1;GSK3 0.081 0.000405827 81.65 _LVPRPGSGSSSGSSNSGSQPGSHPGpSQSGSGER_ LVPRPGSGSSSGSSNS(0.001)GS(0.004)QPGS(0.08)HPGS(0.318)QS(0.318)GS(0.279)GER LVPRPGS(-56.68)GS(-56.68)S(-56.68)S(-56.68)GS(-47.76)S(-39.45)NS(-24.61)GS(-18.86)QPGS(-6.01)HPGS(0)QS(0)GS(-0.57)GER 26 4 787.84735 -1.2086 0 0 0 0 0 0 0 0 0 325 266 775 775 3794;4418 4287;5026 36026 22300 Mix4_TiO2_Reinj_1_1 2466 36027 22301 Mix4_TiO2_Reinj_1_5 2920 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.482856 0 0.084539 -9.87003 1.44683 29.893 0 0 0.482856 0 0.000405827 81.65 0.264656 -0.972338 1.52188 32.5 0.0245127 -11.0938 1.01586 44.302 1 S SHPGSQSGSGERF 0.000405827 81.65 _LVPRPGSGSSSGSSNSGSQPGSHPGSQpSGSGER_ LVPRPGSGSSSGSSNSGSQPGSHPGS(0.034)QS(0.483)GS(0.483)GER LVPRPGS(-52.1)GS(-52.1)S(-47.45)S(-50.51)GS(-50.51)S(-47.45)NS(-43.52)GS(-51.11)QPGS(-31.12)HPGS(-11.54)QS(0)GS(0)GER 28 3 1050.1274 -1.3184 0 0 0 0 0 0 0 0 0 326 266 777 777 3794;4418 4287;5026 42075 25922 Mix4_TiO2_1_5 1362 36027 22301 Mix4_TiO2_Reinj_1_5 2920 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.820466 9.72794 0.820466 9.72794 1.44683 29.893 0 0 0.784988 5.75798 0.000405827 81.65 0.118319 -4.4686 1.52188 32.5 0.00689196 -16.6043 1.01586 44.302 1 S PGSQSGSGERFRV CK1 0.143 0.000405827 81.65 _PGSGSSSGSSNSGSQPGSHPGSQSGpSGER_ PGS(0.001)GS(0.001)S(0.001)S(0.001)GS(0.001)S(0.001)NS(0.001)GS(0.001)QPGS(0.001)HPGS(0.087)QS(0.085)GS(0.82)GER PGS(-29.89)GS(-29.89)S(-29.89)S(-29.89)GS(-29.89)S(-29.89)NS(-29.89)GS(-29.89)QPGS(-29.51)HPGS(-9.73)QS(-9.87)GS(9.73)GER 26 3 895.02526 -0.49987 2052000 0.59923 71995 0 0 1980000 0 0 0 327 266 922 922 4760 5407 45380 27751 Mix4_TiO2_Reinj_1_5 2362 45380 27751 Mix4_TiO2_Reinj_1_5 2362 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.996181 26.4743 0.977094 16.573 0.044788 50.181 0 0 0.996181 26.4743 0.00624829 71.649 0 0 0.975491 18.2545 0.123514 36.877 0.865079 8.64285 0.191252 31.08 1 S IVRQTQSASSTLQ 0.00624829 71.649 _QTQpSASSTLQK_ QT(0.002)QS(0.996)AS(0.002)STLQK QT(-26.47)QS(26.47)AS(-28.12)S(-44.82)T(-52.91)LQK 4 2 629.78738 0.30031 1273800 128430 0 0 475940 0 336710 332760 328 266 924 924 4760 5407 45379 27750 Mix4_TiO2_Reinj_1_5 1895 45380 27751 Mix4_TiO2_Reinj_1_5 2362 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.327902 0 0.0215099 -16.573 0.044788 50.181 0 0 0.327902 0 0.00624829 71.649 0 0 0.0145805 -18.2545 0.123514 36.877 0.014201 -17.8474 0.191252 31.08 1 S RQTQSASSTLQKH CK1 0.143 0.00624829 71.649 _QTQSApSSTLQK_ QT(0.008)QS(0.008)AS(0.328)S(0.328)T(0.328)LQK QT(-16.22)QS(-15.89)AS(0)S(0)T(0)LQK 6 2 629.78738 -0.1477 0 0 0 0 0 0 0 0 329 266 925 925 4760 5407 45379 27750 Mix4_TiO2_Reinj_1_5 1895 45380 27751 Mix4_TiO2_Reinj_1_5 2362 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.327902 0 9.31059E-05 -40.2096 0.044788 50.181 0 0 0.327902 0 0.00624829 71.649 0 0 0.00202455 -26.829 0.123514 36.877 0.0018039 -26.8084 0.191252 31.08 1 S QTQSASSTLQKHK CK1 0.081 0.00624829 71.649 _QTQSApSSTLQK_ QT(0.008)QS(0.008)AS(0.328)S(0.328)T(0.328)LQK QT(-16.22)QS(-15.89)AS(0)S(0)T(0)LQK 7 2 629.78738 -0.1477 0 0 0 0 0 0 0 0 330 266 785 785 5742;6581 6543;7532 66719 40922 Mix4_InSol_TiO2_1 1454 56425 34457 Mix4_InSol_Tio2_Reinj_1 1231 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.578358 2.14561 0.302875 -0.970405 0.393081 18.639 0.302569 -0.810285 0.463361 15.585 0.578358 2.14561 0.0370454 54.615 0.454154 0 0.00644444 79.788 1 S ERFRVRSSSKSEG CAMK2;GSK3;PKA/AKT 0.001764 0.00644444 79.788 _VRpSSSKSEGSPSQR_ VRS(0.578)S(0.353)S(0.057)KS(0.01)EGS(0.001)PS(0.001)QR VRS(2.15)S(-2.15)S(-10.07)KS(-17.75)EGS(-27.37)PS(-27.37)QR 3 2 786.36231 -0.006586 123250 0 0 0 0 0 123250 0 331 266 786 786 5742;6581 6543;7532 56425 34457 Mix4_InSol_Tio2_Reinj_1 1231 56425 34457 Mix4_InSol_Tio2_Reinj_1 1231 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.570544 1.64837 0.378708 0.970405 0.393081 18.639 0.36463 0.810285 0.463361 15.585 0.555947 1.44796 0.0370454 54.615 0.570544 1.64837 0.00644444 79.788 1 S RFRVRSSSKSEGS PKA 0.042 0.00644444 79.788 _SpSSKSEGSPSQR_ S(0.39)S(0.571)S(0.039)KSEGSPSQR S(-1.65)S(1.65)S(-11.65)KS(-38.63)EGS(-79.79)PS(-79.79)QR 2 2 658.77755 -0.28411 664190 0 0 0 0 0 316390 347800 332 266 933 933 5753 6556 56565 34535 Mix4_TiO2_1_5 6087 56565 34535 Mix4_TiO2_1_5 6087 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.489214 1.62985 0.489214 1.62985 0.0614432 47.708 0 0 0.284444 0 0.294641 23.996 0.195275 -3.15164 0.31851 22.063 0.230814 -0.993856 0.317674 22.131 1 S LQKHKSSSSFTPF 0.0614432 47.708 _SpSSSFTPFIDPR_ S(0.336)S(0.489)S(0.017)S(0.157)FT(0.001)PFIDPR S(-1.63)S(1.63)S(-14.52)S(-4.94)FT(-29.01)PFIDPR 2 2 710.81086 0.21211 0 0 0 0 0 0 0 0 333 266 934 934 5753 6556 56563 34533 Mix4_InSol_Tio2_Reinj_1 7501 56565 34535 Mix4_TiO2_1_5 6087 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.290167 0 0.0921518 -9.31371 0.0614432 47.708 0 0 0.284444 0 0.294641 23.996 0.237402 -2.30325 0.31851 22.063 0.290167 0 0.317674 22.131 1 S QKHKSSSSFTPFI 0.0614432 47.708 _SSpSSFTPFIDPR_ S(0.185)S(0.231)S(0.29)S(0.29)FT(0.004)PFIDPR S(-1.96)S(-0.99)S(0)S(0)FT(-18.34)PFIDPR 3 2 710.81086 0.067159 0 0 0 0 0 0 0 0 334 266 935 935 5753 6556 56564 34534 Mix4_TiO2_1_1 5687 56565 34535 Mix4_TiO2_1_5 6087 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.786819 9.31371 0.786819 9.31371 0.0614432 47.708 0 0 0.213888 -1.2381 0.294641 23.996 0.403469 2.30325 0.31851 22.063 0.290167 0 0.317674 22.131 1 S KHKSSSSFTPFID CK1 0.081 0.0614432 47.708 _SSSpSFTPFIDPR_ S(0.052)S(0.069)S(0.092)S(0.787)FT(0.001)PFIDPR S(-11.82)S(-10.58)S(-9.31)S(9.31)FT(-31.56)PFIDPR 4 2 710.81086 0.010851 32658 32658 0 0 0 0 0 0 335 266 706 706 6269;6270 7161;7162;7163 62529 38044 Mix4_InSol_Tio2_Reinj_1 3031 62489 38031 Mix4_TiO2_Reinj_1_5 2835 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.889473 9.25162 0.37354 0 0.136308 35.064 0.0354422 -14.3423 0.0600653 42.669 0.974471 20.4884 0.229949 27.305 0 0 0.830102 10.0841 0.00260956 73.808 0.889473 9.25162 0.00443599 68.175 1 S VPVRTTSRSPVLS CAMK2;PKA/AKT 0.00111111 0.00449262 113.91 _TTpSRSPVLSRR_ T(0.002)T(0.003)S(0.889)RS(0.106)PVLSRR T(-26.57)T(-25.32)S(9.25)RS(-9.25)PVLS(-34.99)RR 3 3 447.23291 -0.44952 1631700 0 0 0 57379 0 1289300 284950 336 266 708 708 6269;6270 7161;7162;7163 62489 38031 Mix4_TiO2_Reinj_1_5 2835 62489 38031 Mix4_TiO2_Reinj_1_5 2835 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.999996 53.6455 0.999747 35.9706 0.00382649 110.2 0.963288 14.3423 0.0600653 42.669 0.999996 53.6455 0.00449262 113.91 0 0 0.976416 16.2523 0.00260956 73.808 0.997122 26.6213 0.00443599 68.175 1 S VRTTSRSPVLSRR CK1;GSK3;Proline-directed 0.05 0.00449262 113.91 _TTSRpSPVLSR_ TTSRS(1)PVLSR T(-84.74)T(-83.33)S(-53.65)RS(53.65)PVLS(-71.91)R 5 2 592.29518 -0.38646 23489000 2284400 277600 0 14108000 0 2813800 4006000 337 268 613 613 3183;4590;4591 3613;5211;5212 43482 26671 Mix4_TiO2_Reinj_1_5 5018 30237 18823 Mix4_TiO2_Reinj_1_5 4426 O95835;O95835-2 O95835 O95835 >sp|O95835|LATS1_HUMAN Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 PE=1 SV=1;>sp|O95835-2|LATS1_HUMAN Isoform 2 of Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 0.99135 20.7474 0.985235 20.5469 0.0022597 88.313 0.986045 20.2896 0.0120244 58.575 0.99135 20.7474 0.00280145 121.53 0 0 0.986879 20.8521 0.000978775 78.837 0.978961 18.3483 0.0341538 51.248 1 S KKQITTSPITVRK Proline-directed 0.05 0.00280145 121.53 _QITTpSPITVR_ QITT(0.008)S(0.991)PITVR QIT(-40.42)T(-20.75)S(20.75)PIT(-36.65)VR 5 2 598.30775 0.087144 7606500 1504800 111520 0 4767000 0 916240 306890 338 268 278 278 5081 5778 49155 30016 Mix4_InSol_TiO2_1 6135 49155 30016 Mix4_InSol_TiO2_1 6135 O95835;O95835-2 O95835 O95835 >sp|O95835|LATS1_HUMAN Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 PE=1 SV=1;>sp|O95835-2|LATS1_HUMAN Isoform 2 of Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 0.999992 51.1514 0 0 0.999992 51.1514 0.00819065 76.5 0.999432 32.6447 0.0455457 52.208 1 S SQTKRYSGNMEYV CK1;PKA 0.042 0.00819065 76.5 _RYpSGNMEYVISR_ RYS(1)GNMEYVISR RY(-51.15)S(51.15)GNMEY(-76.5)VIS(-76.5)R 3 2 777.84217 0.045099 215710 0 0 0 0 0 135070 80640 339 268 462 462 5521 6286 53892 32963 Mix4_TiO2_1_5 4458 53890 32960 Mix4_InSol_Tio2_Reinj_1 5501 O95835;O95835-2 O95835 O95835 >sp|O95835|LATS1_HUMAN Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 PE=1 SV=1;>sp|O95835-2|LATS1_HUMAN Isoform 2 of Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 0.738357 4.50558 0.738357 4.50558 0.00289998 113.75 0 0 0.624066 2.20119 0.00318063 119.19 0.135851 -8.03525 0.00291677 120.82 0.00133141 -28.7511 0.00118281 131.53 1 S PNIPVRSNSFNNP 0.00118281 131.53 _pSNSFNNPLGNR_ S(0.738)NS(0.262)FNNPLGNR S(4.51)NS(-4.51)FNNPLGNR 1 2 650.27752 0.0068899 1020600 854460 0 0 166110 0 0 0 340 268 464 464 5521 6286 53890 32960 Mix4_InSol_Tio2_Reinj_1 5501 53890 32960 Mix4_InSol_Tio2_Reinj_1 5501 O95835;O95835-2 O95835 O95835 >sp|O95835|LATS1_HUMAN Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 PE=1 SV=1;>sp|O95835-2|LATS1_HUMAN Isoform 2 of Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 0.998669 28.7511 0.961089 13.9269 0.00289998 113.75 0 0 0.841258 7.24239 0.00318063 119.19 0.864149 8.03525 0.00291677 120.82 0.998669 28.7511 0.00118281 131.53 1 S IPVRSNSFNNPLG CAMK2 0.042 0.00118281 131.53 _SNpSFNNPLGNR_ S(0.001)NS(0.999)FNNPLGNR S(-28.75)NS(28.75)FNNPLGNR 3 2 650.27752 -0.27796 3449600 40943 0 0 2157300 0 540570 710840 341 272 181 181 957;4429;4991 1078;5039;5674 42132 25959 Mix4_TiO2_1_3 4725 9045 5525 Mix4_TiO2_1_3 4398 O96013 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1 1 80.1451 1 80.1451 5.38124E-25 171.38 0.999998 56.3433 5.20088E-07 107.89 0 0 1 85.5567 1.51747E-24 163.05 1 70.1758 8.30451E-05 96.366 0.999992 51.0879 8.93481E-07 100.55 0.99999 50.0514 0.00038479 87.321 1 S RDKRPLSGPDVGT CAMK2;CK2;PKA 0.003024 5.38124E-25 171.38 _PLpSGPDVGTPQPAGLASGAK_ PLS(1)GPDVGTPQPAGLASGAK PLS(80.15)GPDVGT(-80.15)PQPAGLAS(-134.73)GAK 3 2 950.46423 1.0394 198660000 160.83 29332000 453480 0 132830000 72595 18078000 17895000 342 272 195 195 957;4429;4991 1078;5039;5674 48170 29453 Mix4_TiO2_Reinj_1_4 5167 9045 5525 Mix4_TiO2_1_3 4398 O96013 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1 0.897351 10.8871 0.0567673 -11.9356 5.38124E-25 171.38 0.242992 -3.25383 5.20088E-07 107.89 0 0 0.897351 10.8871 1.51747E-24 163.05 0.00306477 -25.0835 8.30451E-05 96.366 0.0345028 -13.3175 8.93481E-07 100.55 0.117857 -6.17873 0.00038479 87.321 1 S QPAGLASGAKLAA 5.38124E-25 171.38 _RPLSGPDVGTPQPAGLApSGAK_ RPLS(0.029)GPDVGT(0.073)PQPAGLAS(0.897)GAK RPLS(-14.83)GPDVGT(-10.89)PQPAGLAS(10.89)GAK 18 2 1028.5148 0.03378 421900 0.34156 0 0 0 421900 0 0 0 343 272 167 167 1560;5733 1753;6534 14285 8704 Mix4_TiO2_1_3 929 14285 8704 Mix4_TiO2_1_3 929 O96013 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1 1 82.4466 1 82.4466 0.00278667 82.447 0.905392 12.8194 0.489509 12.819 0.999908 43.3778 0.0677266 43.378 0.999971 48.3342 0.051016 48.334 1 S KSSREGSGGPQES CAMK2;CK1 0.042 0.00278667 82.447 _EGpSGGPQESSR_ EGS(1)GGPQESSR EGS(82.45)GGPQES(-82.45)S(-82.45)R 3 2 585.72478 0.21805 664170 4.0831 104130 0 0 27910 0 237370 294760 344 272 142 142 1947;1948 2203;2205 17813 10663 Mix4_TiO2_Reinj_1_3 2238 17812 10662 Mix4_TiO2_Reinj_1_3 2008 O96013 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1 0.796302 5.92092 2.56847E-06 -55.9032 0.0136547 69.823 0.796302 5.92092 0.00282431 83.103 0 0 0 0 1 S GRFAGHSEAGGGS 0.00282431 83.103 _FAGHpSEAGGGSGDR_ FAGHS(0.796)EAGGGS(0.204)GDR FAGHS(5.92)EAGGGS(-5.92)GDR 5 2 692.76751 0.20985 372490 1.1189 0 0 0 372490 0 0 0 345 272 148 148 1947;1948 2203;2205 17812 10662 Mix4_TiO2_Reinj_1_3 2008 17812 10662 Mix4_TiO2_Reinj_1_3 2008 O96013 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1 1 83.1032 0.999997 55.9032 0.0136547 69.823 1 83.1032 0.00282431 83.103 0 0 0 0 1 S SEAGGGSGDRRRA 0.00282431 83.103 _FAGHSEAGGGpSGDR_ FAGHSEAGGGS(1)GDR FAGHS(-83.1)EAGGGS(83.1)GDR 11 3 462.18077 0.15494 4368600 13.123 112530 0 0 4256100 0 0 0 346 272 258 258 2106;2107;2108 2385;2386;2387;2388 19298 11724 Mix4_TiO2_Reinj_1_4 6536 19295 11720 Mix4_TiO2_Reinj_1_3 6656 O96013;O96013-4;O96013-3 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 0.994761 22.7873 0.728381 4.48458 7.75803E-05 97.928 0 0 0.994761 22.7873 2.59172E-07 113.28 0.84328 7.64296 2.09082 40.841 0.513137 0.263938 1.75633 45.359 1 S RARGAPSPGVLGP Proline-directed 0.05 2.59172E-07 113.28 _GAPpSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPR_ GAPS(0.995)PGVLGPHAS(0.005)EPQLAPPACTPAAPAVPGPPGPR GAPS(22.79)PGVLGPHAS(-22.79)EPQLAPPACT(-55.12)PAAPAVPGPPGPR 4 3 1152.5692 -0.31027 7960000 752410 0 0 6435900 0 427830 343910 347 272 267 267 2106;2107;2108 2385;2386;2387;2388 19290 11711 Mix4_TiO2_1_3 5946 19295 11720 Mix4_TiO2_Reinj_1_3 6656 O96013;O96013-4;O96013-3 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 0.999907 40.45 0.999907 40.45 7.75803E-05 97.928 0 0 0.996776 26.3331 2.59172E-07 113.28 0.455388 -0.774014 0.604419 61.004 0.48288 -0.263938 1.75633 45.359 1 S VLGPHASEPQLAP 2.59172E-07 113.28 _GAPSPGVLGPHApSEPQLAPPACTPAAPAVPGPPGPR_ GAPSPGVLGPHAS(1)EPQLAPPACTPAAPAVPGPPGPR GAPS(-40.45)PGVLGPHAS(40.45)EPQLAPPACT(-55.14)PAAPAVPGPPGPR 13 3 1152.5692 -0.89785 6046600 936360 0 0 5110200 0 0 0 348 272 291 291 2107;2108;5576 2386;2387;2388;6354 54553 33413 Mix4_TiO2_Reinj_1_5 1409 19310 11726 Mix4_TiO2_Reinj_1_3 6280 O96013;O96013-4;O96013-3;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 1 4.74085 1 18.9042 0.35342 29.134 0 0 1 4.74085 0.077391 76.746 0 0 0.967717 14.8244 0.604419 61.004 0.824646 6.87414 1.75633 45.359 1 S GPPGPRSPQREPQ CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.077391 76.746 _pSPQREPQR_ S(1)PQREPQR S(4.74)PQREPQR 1 2 539.24549 0.040756 70636000 505710 0 0 66235000 0 1576800 2319100 349 272 104 104 4845;5528 5506;6294;6295 46407 28448 Mix4_TiO2_Reinj_1_6 1573 46403 28425 Mix4_TiO2_Reinj_1_3 1803 O96013;O96013-4;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-2|PAK4_HUMAN Isoform 2 of Serine/threonine-protein k 1 26.8836 1 40.6964 0.00359154 72.191 1 49.8493 0.0411719 49.849 1 26.8836 0.000962969 83.019 0 0 1 5.61436 0.0416522 49.697 1 4.13565 0.0411719 49.849 1 S NSLRRDSPPPPAR CAMK2;PKA;Proline-directed 0.004788 0.000962969 83.019 _RDpSPPPPAR_ RDS(1)PPPPAR RDS(26.88)PPPPAR 3 2 536.75041 -0.0692 58963000 361.7 5718500 277140 0 30161000 0 10947000 11858000 350 272 474 474 4929;5484 5604;5605;6240;6241 53482 32679 Mix4_TiO2_Reinj_1_5 8073 53480 32677 Mix4_TiO2_Reinj_1_4 8225 O96013;O96013-4;O96013-3;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 1 87.3391 1 82.381 3.50303E-16 169.97 0.984581 18.2601 0.131136 45.489 1 87.3391 1.27668E-25 196.46 0.14294 -7.46303 1.02856 15.413 0.999999 62.7492 1.73432E-12 147.79 1 64.0968 3.51023E-13 154.86 1 S EVPRRKSLVGTPY AURORA;AURORA-1;AURORA-A;CAMK2;CHK1;PKA;PKD 0.004788 1.27668E-25 196.46 _pSLVGTPYWM(ox)APELISR_ S(1)LVGTPYWMAPELISR S(87.34)LVGT(-87.34)PY(-156.12)WMAPELIS(-175.15)R 1 2 958.45482 0.071833 57569000 7987000 68622 0 41582000 0 3527800 4403800 351 272 97 97 5528 6294;6295 53993 33061 Mix4_TiO2_Reinj_1_3 2590 53992 33057 Mix4_TiO2_Reinj_1_3 2586 O96013;O96013-4;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-2|PAK4_HUMAN Isoform 2 of Serine/threonine-protein k 0.965071 14.3512 0.927831 11.0911 0.0293324 58.916 0.965071 14.3512 0.00736094 75.784 0.781949 5.5209 0.0124098 71.002 0.395725 -2.02222 0.0926232 43.883 2 S NMSVTRSNSLRRD CK1 0.143 0.00736094 75.784 _pSNSLRRDpSPPPPAR_ S(0.965)NS(0.049)LRRDS(0.986)PPPPAR S(14.35)NS(-14.35)LRRDS(18.39)PPPPAR 1 2 855.37965 0.03133 2935400 1246500 0 0 1135300 0 553720 0 352 272 99 99 5528 6294;6295 53991 33054 Mix4_TiO2_1_4 2295 53992 33057 Mix4_TiO2_Reinj_1_3 2586 O96013;O96013-4;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-2|PAK4_HUMAN Isoform 2 of Serine/threonine-protein k 0.997572 26.1372 0.997572 26.1372 0.0293324 58.916 0.912436 10.1788 0.00736094 75.784 0.854078 7.67146 0.0124098 71.002 0.96904 14.9549 0.0926232 43.883 2 S SVTRSNSLRRDSP CAMK2;CHK1;CK1;PKC;PKD 0.001764 0.00736094 75.784 _SNpSLRRDpSPPPPAR_ S(0.002)NS(0.998)LRRDS(1)PPPPAR S(-26.14)NS(26.14)LRRDS(58.92)PPPPAR 3 3 570.58886 0.54047 8481000 438460 0 0 4832200 0 1220200 1990100 353 274 67 67 3955 4504 37469 23024 Mix4_TiO2_Reinj_1_4 8463 37469 23024 Mix4_TiO2_Reinj_1_4 8463 O96020;O96020-2 O96020 O96020 >sp|O96020|CCNE2_HUMAN G1/S-specific cyclin-E2 OS=Homo sapiens GN=CCNE2 PE=1 SV=1;>sp|O96020-2|CCNE2_HUMAN Isoform SV of G1/S-specific cyclin-E2 OS=Homo sapiens GN=CCNE2 0.995058 23.2951 0.921953 10.8048 0.335246 39.175 0.995058 23.2951 0.00125389 78.806 1 S VLSGGISPCIIIE CK1;Proline-directed 0.05 0.00125389 78.806 _NCWPPVLSGGIpSPCIIIETPHK_ NCWPPVLS(0.005)GGIS(0.995)PCIIIETPHK NCWPPVLS(-23.3)GGIS(23.3)PCIIIET(-35.47)PHK 12 3 852.41106 0.17399 308140 68401 0 0 239740 0 0 0 354 274 21 21 4698 5336 44678 27402 Mix4_TiO2_1_4 4059 44678 27402 Mix4_TiO2_1_4 4059 O96020;O96020-2 O96020 O96020 >sp|O96020|CCNE2_HUMAN G1/S-specific cyclin-E2 OS=Homo sapiens GN=CCNE2 PE=1 SV=1;>sp|O96020-2|CCNE2_HUMAN Isoform SV of G1/S-specific cyclin-E2 OS=Homo sapiens GN=CCNE2 0.999753 36.0827 0.999753 36.0827 2.01736E-22 173.32 0 0 0.999067 30.3085 3.96885E-22 170.76 0.997744 26.4655 7.26119E-16 138.79 0.995463 24.0696 8.60386E-05 96.508 1 S QPSQTESPQEAQI CK1;CK2;Proline-directed 0.05 2.01736E-22 173.32 _QQPQPSQTEpSPQEAQIIQAK_ QQPQPSQTES(1)PQEAQIIQAK QQPQPS(-60.85)QT(-36.08)ES(36.08)PQEAQIIQAK 10 3 772.70043 -0.49313 9382600 15.806 2009400 0 0 4679600 0 1600600 1093000 355 274 339 339 5804 6615 57197 34864 Mix4_InSol_TiO2_1 3229 57197 34864 Mix4_InSol_TiO2_1 3229 O96020;O96020-2 O96020 O96020 >sp|O96020|CCNE2_HUMAN G1/S-specific cyclin-E2 OS=Homo sapiens GN=CCNE2 PE=1 SV=1;>sp|O96020-2|CCNE2_HUMAN Isoform SV of G1/S-specific cyclin-E2 OS=Homo sapiens GN=CCNE2 0.999575 34.2008 0 0 0.74095 7.57436 0.574116 7.5744 0 0 0.999575 34.2008 0.0202284 62.191 0.987118 21.1838 0.143528 41.52 1 S NVVKSTSPVKLKT CDK1;CDK2;CHK1;PKD;Proline-directed 0.0057 0.0202284 62.191 _STpSPVKLK_ STS(1)PVKLK S(-34.2)T(-43.42)S(34.2)PVKLK 3 2 470.24918 -0.40609 131440 0 0 0 0 0 80099 51344 356 276 936 936 234 269 2328 1494 Mix4_TiO2_Reinj_1_5 4740 2328 1494 Mix4_TiO2_Reinj_1_5 4740 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.826522 7.22733 0.789368 6.76179 0.00037967 86.672 0.826522 7.22733 6.98356E-05 96.615 1 S GGKPSQSPSQEAA Proline-directed 0.05 6.98356E-05 96.615 _AGGKPSQpSPSQEAAGEAVLGAK_ AGGKPS(0.017)QS(0.827)PS(0.157)QEAAGEAVLGAK AGGKPS(-16.87)QS(7.23)PS(-7.23)QEAAGEAVLGAK 8 3 707.33884 0.022467 1243100 345230 0 0 897910 0 0 0 357 276 695 695 1814 2047 16643 10021 Mix4_TiO2_Reinj_1_5 5581 16643 10021 Mix4_TiO2_Reinj_1_5 5581 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.333333 0 0 0 0.333333 0 0.0163461 67.274 1 S NGALRESGGSGFR NEK6;PKA 0.042 0.0163461 67.274 _EpSGGSGFRSPHLWK_ ES(0.333)GGS(0.333)GFRS(0.333)PHLWK ES(0)GGS(0)GFRS(0)PHLWK 2 2 812.86703 -0.0088865 0 0 0 0 0 0 0 0 358 276 698 698 1814 2047 16643 10021 Mix4_TiO2_Reinj_1_5 5581 16643 10021 Mix4_TiO2_Reinj_1_5 5581 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.333333 0 0 0 0.333333 0 0.0163461 67.274 1 S LRESGGSGFRSPH CK1;GSK3 0.081 0.0163461 67.274 _EpSGGSGFRSPHLWK_ ES(0.333)GGS(0.333)GFRS(0.333)PHLWK ES(0)GGS(0)GFRS(0)PHLWK 5 2 812.86703 -0.0088865 0 0 0 0 0 0 0 0 359 276 702 702 1814 2047 16642 10020 Mix4_TiO2_Reinj_1_5 5627 16643 10021 Mix4_TiO2_Reinj_1_5 5581 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.986762 20.2129 0 0 0.986762 20.2129 0.0163461 67.274 1 S GGSGFRSPHLWKK CK1;Proline-directed 0.05 0.0163461 67.274 _ESGGSGFRpSPHLWK_ ES(0.004)GGS(0.009)GFRS(0.987)PHLWK ES(-24.1)GGS(-20.21)GFRS(20.21)PHLWK 9 3 542.24711 -0.27092 1188400 0 0 0 1188400 0 0 0 360 276 588 588 2375 2688 21985 13675 Mix4_TiO2_Reinj_1_5 6907 21985 13675 Mix4_TiO2_Reinj_1_5 6907 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 1 135.131 1 94.0029 1.7555E-10 122.1 1 98.822 1.24238E-06 105.68 1 135.131 1.39334E-11 136.18 0 0 1 81.4603 1.83525E-06 99.778 1 80.6444 1.58899E-06 102.24 1 S DHEPAVSPLLPRK Proline-directed 0.05 1.39334E-11 136.18 _GQGESDPLDHEPAVpSPLLPR_ GQGESDPLDHEPAVS(1)PLLPR GQGES(-135.13)DPLDHEPAVS(135.13)PLLPR 15 3 732.01072 -0.012759 11169000 2531900 273110 0 7087400 0 629940 646170 361 276 16 16 5000 5686 48264 29485 Mix4_TiO2_Reinj_1_5 7212 48264 29485 Mix4_TiO2_Reinj_1_5 7212 P00519-2 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 1 55.9065 0 0 1 55.9065 0.0254818 55.907 1 S GDQRRPSLPALHF AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.004788 0.0254818 55.907 _RPpSLPALHFIK_ RPS(1)LPALHFIK RPS(55.91)LPALHFIK 3 3 453.583 -0.64351 353140 0 0 0 353140 0 0 0 362 276 735 735 5140 5851 49716 30382 Mix4_TiO2_1_5 1957 49717 30383 Mix4_TiO2_Reinj_1_5 2477 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.499613 0 0.499613 0 0.126615 37.606 0.258938 -2.69964 0.0722437 44.65 1 S SKRFLRSCSASCV GSK3 0.081 0.0722437 44.65 _pSCSASCVPHGAK_ S(0.5)CS(0.5)AS(0.001)CVPHGAK S(0)CS(0)AS(-28.1)CVPHGAK 1 2 670.75979 -0.076007 0 0 0 0 0 0 0 0 363 276 737 737 5140 5851 49717 30383 Mix4_TiO2_Reinj_1_5 2477 49717 30383 Mix4_TiO2_Reinj_1_5 2477 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.895177 9.47143 0.499613 0 0.126615 37.606 0.895177 9.47143 0.0722437 44.65 1 S RFLRSCSASCVPH CAMK2;PKA/AKT 0.00111111 0.0722437 44.65 _SCpSASCVPHGAK_ S(0.101)CS(0.895)AS(0.004)CVPHGAK S(-9.47)CS(9.47)AS(-23.81)CVPHGAK 3 2 670.75979 -0.69839 419190 0 0 0 419190 0 0 0 364 277 1025 1025 337 380;381;382 3098 1881 Mix4_TiO2_Reinj_1_1 8352 3110 1885 Mix4_TiO2_Reinj_1_1 7912 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.678663 5.627 0.318796 0 0.049787 65.733 0 0 0.678663 5.627 1.2087E-07 102.73 0 0 1 S PQQGFFSSPSTSR 1.2087E-07 102.73 _ALM(ox)DEEDMDDVVDADEYLIPQQGFFpSSPSTSR_ ALMDEEDMDDVVDADEYLIPQQGFFS(0.679)S(0.187)PS(0.045)T(0.045)S(0.045)R ALMDEEDMDDVVDADEY(-56.7)LIPQQGFFS(5.63)S(-5.63)PS(-11.86)T(-11.86)S(-11.86)R 26 3 1235.1828 0.15833 254390 0.40639 0 0 0 254390 0 0 0 365 277 1026 1026 337 380;381;382 3109 1884 Mix4_TiO2_1_5 7627 3110 1885 Mix4_TiO2_Reinj_1_1 7912 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.753789 7.13164 0.753789 7.13164 0.049787 65.733 0 0 0.39686 0 1.2087E-07 102.73 0 0 1 S QQGFFSSPSTSRT GSK3;Polo box;Proline-directed 0.00405 1.2087E-07 102.73 _ALM(ox)DEEDM(ox)DDVVDADEYLIPQQGFFSpSPSTSR_ ALMDEEDMDDVVDADEYLIPQQGFFS(0.146)S(0.754)PS(0.033)T(0.033)S(0.033)R ALMDEEDMDDVVDADEY(-50.77)LIPQQGFFS(-7.13)S(7.13)PS(-13.53)T(-13.53)S(-13.53)R 27 3 1240.5145 0.25339 212530 0.33953 212530 0 0 0 0 0 0 366 277 1030 1030 337 380;381;382 3096 1879 Mix4_TiO2_1_1 7546 3110 1885 Mix4_TiO2_Reinj_1_1 7912 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.373544 0 0.373544 0 0.049787 65.733 0 0 0.0885231 -6.07752 1.2087E-07 102.73 0 0 1 S FSSPSTSRTPLLS CK1 0.143 1.2087E-07 102.73 _ALMDEEDM(ox)DDVVDADEYLIPQQGFFSSPSpTSR_ ALMDEEDMDDVVDADEYLIPQQGFFS(0.084)S(0.084)PS(0.084)T(0.374)S(0.374)R ALMDEEDMDDVVDADEY(-30.68)LIPQQGFFS(-6.49)S(-6.49)PS(-6.49)T(0)S(0)R 31 3 1235.1828 0.26532 0 0 0 0 0 0 0 0 0 367 277 695 695 1690 1897 15433 9306 Mix4_InSol_Tio2_Reinj_1 7423 15447 9329 Mix4_TiO2_Reinj_1_5 6957 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.910675 10.0839 0.659009 2.86149 3.67315E-26 186.13 0.591986 1.61637 2.40031E-21 166.94 0.5 0 2.09772E-31 196.16 0.135165 -8.06068 0.000101 97.175 0.665371 2.98499 1.41058E-15 143.44 0.910675 10.0839 0.000581321 88.97 1 S VEPLTPSGEAPNQ NEK6 0.076 2.09772E-31 196.16 _ELVEPLTPpSGEAPNQALLR_ ELVEPLT(0.089)PS(0.911)GEAPNQALLR ELVEPLT(-10.08)PS(10.08)GEAPNQALLR 9 2 1057.5301 -0.0054146 4879100 233210 137150 0 1133700 0 1589100 1786000 368 277 1162 1162 2444 2771 22972 14366 Mix4_TiO2_1_6 5348 22974 14368 Mix4_TiO2_Reinj_1_5 7141 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.579695 1.39852 0.579695 1.39852 4.5762E-10 121.31 0 0 0.00596462 -22.2182 1.55322E-15 142.1 0.538834 0.676294 0.168408 42.067 0.216103 -5.59199 0.586499 30.35 1 S HWAQKGSHQISLD GSK3 0.081 1.55322E-15 142.1 _GpSHQISLDNPDYQQDFFPK_ GS(0.58)HQIS(0.42)LDNPDYQQDFFPK GS(1.4)HQIS(-1.4)LDNPDY(-34.41)QQDFFPK 2 3 772.67047 -0.41531 186310 18535 0 0 0 0 167780 0 369 277 1166 1166 2444 2771 22974 14368 Mix4_TiO2_Reinj_1_5 7141 22974 14368 Mix4_TiO2_Reinj_1_5 7141 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.997001 25.2174 0.994711 22.7434 4.5762E-10 121.31 0 0 0.997001 25.2174 1.55322E-15 142.1 0.461132 -0.676294 0.168408 42.067 0.783175 5.59199 0.586499 30.35 1 S KGSHQISLDNPDY CK1 0.143 1.55322E-15 142.1 _GSHQIpSLDNPDYQQDFFPK_ GS(0.003)HQIS(0.997)LDNPDYQQDFFPK GS(-25.22)HQIS(25.22)LDNPDY(-80.14)QQDFFPK 6 3 772.67047 -0.020706 2364200 473080 0 0 1735600 0 0 155560 370 277 991 991 3866 4383;4384 36688 22609 Mix4_TiO2_Reinj_1_5 5434 36688 22609 Mix4_TiO2_Reinj_1_5 5434 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.998043 27.7648 0.438427 -0.980321 0.317379 26.899 0.998043 27.7648 0.0435424 54.099 0.307852 0 0.059115 49.868 0.88164 9.54735 0.418432 21.082 1 S ERMHLPSPTDSNF CK2;GSK3;Proline-directed 0.05 0.0435424 54.099 _M(ox)HLPpSPTDSNFYR_ MHLPS(0.998)PT(0.002)DSNFYR MHLPS(27.76)PT(-27.76)DS(-35.58)NFY(-49.5)R 5 2 830.84491 -0.046331 329200 0 0 0 259400 0 0 69797 371 277 995 995 3866 4383;4384 36680 22604 Mix4_InSol_TiO2_2 5018 36688 22609 Mix4_TiO2_Reinj_1_5 5434 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.307852 0 0.150446 -3.66135 0.317379 26.899 0.000275966 -35.5829 0.0435424 54.099 0.307852 0 0.059115 49.868 0.0136391 -18.1051 0.418432 21.082 1 S LPSPTDSNFYRAL CK1 0.143 0.0435424 54.099 _MHLPpSPTDSNFYR_ MHLPS(0.308)PT(0.308)DS(0.308)NFY(0.076)R MHLPS(0)PT(0)DS(0)NFY(-6.05)R 9 2 822.84745 0.26988 0 0 0 0 0 0 0 0 372 277 1064 1064 4044 4609 38228 23458 Mix4_TiO2_Reinj_1_5 6096 38227 23457 Mix4_TiO2_1_5 5311 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 1 79.4196 1 91.0404 1.13044E-08 122.4 1 79.4196 1.11555E-05 102.48 0 0 0.999201 30.9732 0.255994 37.283 1 S CPIKEDSFLQRYS PLK1 0.033462 1.13044E-08 122.4 _NGLQSCPIKEDpSFLQR_ NGLQSCPIKEDS(1)FLQR NGLQS(-79.42)CPIKEDS(79.42)FLQR 12 3 657.97132 0.042441 498350 105900 0 0 349700 0 0 42747 373 277 1042 1042 6144 7015 60889 36896 Mix4_TiO2_1_5 6215 60889 36896 Mix4_TiO2_1_5 6215 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.977525 19.5313 0.977525 19.5313 3.29289E-17 153.82 0.910311 13.0481 1.32913E-16 145.16 0.429727 0 0.0152473 62.294 0 0 1 S SSLSATSNNSTVA CK1 0.081 3.29289E-17 153.82 _TPLLSSLSATpSNNSTVACIDR_ TPLLSSLSAT(0.011)S(0.978)NNS(0.011)T(0.001)VACIDR T(-105.7)PLLS(-80.47)S(-89.71)LS(-76.84)AT(-19.53)S(19.53)NNS(-19.53)T(-31.47)VACIDR 11 2 1144.0354 -0.61332 271480 60279 0 0 211200 0 0 0 374 277 1070 1070 6806 7787 69057 42344 Mix4_TiO2_Reinj_1_5 8896 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.315097 0 0.160567 0 6.55873E-08 108.39 0.169211 0 1.5362 30.095 0.315097 0 1.58055E-36 176.58 1 S SFLQRYSSDPTGA PKA 0.042 1.58055E-36 176.58 _pYSSDPTGALTEDSIDDTFLPVPEYINQSVPK_ Y(0.315)S(0.315)S(0.315)DPT(0.055)GALTEDSIDDTFLPVPEYINQSVPK Y(0)S(0)S(0)DPT(-7.61)GALT(-33.64)EDS(-60.2)IDDT(-70.31)FLPVPEY(-126.11)INQS(-126.07)VPK 2 3 1160.199 1.2817 0 0 0 0 0 0 0 0 0 375 277 1071 1071 6806 7787 69057 42344 Mix4_TiO2_Reinj_1_5 8896 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.315097 0 0.160567 0 6.55873E-08 108.39 0.169211 0 1.5362 30.095 0.315097 0 1.58055E-36 176.58 1 S FLQRYSSDPTGAL CAMK2;CHK1;CHK1/2;PKD 0.003192 1.58055E-36 176.58 _pYSSDPTGALTEDSIDDTFLPVPEYINQSVPK_ Y(0.315)S(0.315)S(0.315)DPT(0.055)GALTEDSIDDTFLPVPEYINQSVPK Y(0)S(0)S(0)DPT(-7.61)GALT(-33.64)EDS(-60.2)IDDT(-70.31)FLPVPEY(-126.11)INQS(-126.07)VPK 3 3 1160.199 1.2817 0 0 0 0 0 0 0 0 0 376 277 1081 1081 6806 7787 69056 42343 Mix4_TiO2_Reinj_1_5 8805 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.970395 15.2243 0.880536 11.263 6.55873E-08 108.39 0.140063 -0.821058 1.5362 30.095 0.970395 15.2243 1.58055E-36 176.58 1 S GALTEDSIDDTFL CK2;PLK;PLK1 0.0027378 1.58055E-36 176.58 _YSSDPTGALTEDpSIDDTFLPVPEYINQSVPK_ YSSDPTGALTEDS(0.97)IDDT(0.029)FLPVPEYINQSVPK Y(-69.82)S(-69.82)S(-69.82)DPT(-55.19)GALT(-33.24)EDS(15.22)IDDT(-15.22)FLPVPEY(-128.03)INQS(-143.96)VPK 13 3 1160.199 0.97337 3611400 4.0566 1136300 0 0 2475100 0 0 0 377 277 1096 1096 6806 7787 69054 42340 Mix4_TiO2_2_2 8035 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.545373 5.39452 9.54938E-06 -45.3488 6.55873E-08 108.39 0.545373 5.39452 1.5362 30.095 1.27271E-11 -105.497 1.58055E-36 176.58 1 S PEYINQSVPKRPA 1.58055E-36 176.58 _YSSDPTGALTEDSIDDTFLPVPEYINQpSVPK_ Y(0.024)S(0.024)S(0.024)DPT(0.056)GALT(0.056)EDS(0.058)IDDT(0.056)FLPVPEY(0.157)INQS(0.545)VPK Y(-13.51)S(-13.51)S(-13.51)DPT(-9.92)GALT(-9.92)EDS(-9.76)IDDT(-9.92)FLPVPEY(-5.39)INQS(5.39)VPK 28 3 1160.199 -0.91829 14215 0.015968 0 14215 0 0 0 0 0 378 284 403 403 528 599;600 4934 2980 Mix4_TiO2_Reinj_1_3 1340 4934 2980 Mix4_TiO2_Reinj_1_3 1340 P02545;P02545-3;P02545-2 P02545 P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1;>sp|P02545-3|LMNA_HUMAN Isoform Lamin ADelta10 of Prelamin-A/C OS=Homo sapiens GN=LMNA;>sp|P02545-2|LMNA_HUMAN Isoform Lamin C of Prelamin-A/C OS=Homo sapiens GN=LMNA 0.49999 0 0.491648 0 3.94556E-06 112.58 0.49999 0 5.37637E-17 175.02 0.498843 0 0.19696 39.332 0.463558 0 0.139776 42.652 1 S RSRGRASSHSSQT GSK3;PKA 0.042 5.37637E-17 175.02 _ApSSHSSQTQGGGSVTK_ AS(0.5)S(0.5)HSSQTQGGGSVTK AS(0)S(0)HS(-43.93)S(-63.86)QT(-82.07)QGGGS(-167.19)VT(-175.02)K 2 2 799.84395 -0.25359 226110 0 0 0 226110 0 0 0 379 284 404 404 528 599;600 4942 2982 Mix4_TiO2_Reinj_1_3 1479 4942 2982 Mix4_TiO2_Reinj_1_3 1479 P02545;P02545-3;P02545-2 P02545 P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1;>sp|P02545-3|LMNA_HUMAN Isoform Lamin ADelta10 of Prelamin-A/C OS=Homo sapiens GN=LMNA;>sp|P02545-2|LMNA_HUMAN Isoform Lamin C of Prelamin-A/C OS=Homo sapiens GN=LMNA 0.593841 1.65775 0.491648 0 3.94556E-06 112.58 0.593841 1.65775 6.95069E-16 164.06 0.498843 0 0.19696 39.332 0.463558 0 0.139776 42.652 2 S SRGRASSHSSQTQ CAMK2;PKA/AKT 0.001764 6.95069E-16 164.06 _ASpSHSpSQTQGGGSVTK_ AS(0.406)S(0.594)HS(0.018)S(0.93)QT(0.052)QGGGSVTK AS(-1.66)S(1.66)HS(-17.12)S(12.6)QT(-12.6)QGGGS(-126.73)VT(-164.06)K 3 2 839.82711 0.385 226110 0 0 0 226110 0 0 0 380 284 407 407 528 599;600 4942 2982 Mix4_TiO2_Reinj_1_3 1479 4942 2982 Mix4_TiO2_Reinj_1_3 1479 P02545;P02545-3;P02545-2 P02545 P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1;>sp|P02545-3|LMNA_HUMAN Isoform Lamin ADelta10 of Prelamin-A/C OS=Homo sapiens GN=LMNA;>sp|P02545-2|LMNA_HUMAN Isoform Lamin C of Prelamin-A/C OS=Homo sapiens GN=LMNA 0.930259 12.6 0.000337831 -31.6295 3.94556E-06 112.58 0.930259 12.6 6.95069E-16 164.06 0.000565914 -29.4521 0.19696 39.332 0.000253078 -32.6285 0.139776 42.652 2 S RASSHSSQTQGGG CK1 0.081 6.95069E-16 164.06 _ASpSHSpSQTQGGGSVTK_ AS(0.406)S(0.594)HS(0.018)S(0.93)QT(0.052)QGGGSVTK AS(-1.66)S(1.66)HS(-17.12)S(12.6)QT(-12.6)QGGGS(-126.73)VT(-164.06)K 6 2 839.82711 0.385 91391 0 0 0 91391 0 0 0 381 284 390 390 3697 4169 34826 21609 Mix4_TiO2_1_3 3437 34827 21610 Mix4_TiO2_Reinj_1_3 4083 P02545;P02545-3;P02545-2 P02545 P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1;>sp|P02545-3|LMNA_HUMAN Isoform Lamin ADelta10 of Prelamin-A/C OS=Homo sapiens GN=LMNA;>sp|P02545-2|LMNA_HUMAN Isoform Lamin C of Prelamin-A/C OS=Homo sapiens GN=LMNA 0.91276 14.9676 0.91276 14.9676 0.443806 14.968 0 0 0.390929 -1.924 0.00994839 62.547 0.0531042 -12.4106 0.126646 36.609 0.274793 0.556647 0.734431 0.55665 1 S EERLRLSPSPTSQ NEK6;PKA;Proline-directed 0.042 0.00994839 62.547 _LRLpSPSPTSQR_ LRLS(0.913)PS(0.029)PT(0.029)S(0.029)QR LRLS(14.97)PS(-14.97)PT(-14.97)S(-14.97)QR 4 2 661.33483 0.10425 156150 156150 0 0 0 0 0 0 382 284 392 392 3697 4169 34824 21607 Mix4_InSol_TiO2_1 4463 34827 21610 Mix4_TiO2_Reinj_1_3 4083 P02545;P02545-3;P02545-2 P02545 P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1;>sp|P02545-3|LMNA_HUMAN Isoform Lamin ADelta10 of Prelamin-A/C OS=Homo sapiens GN=LMNA;>sp|P02545-2|LMNA_HUMAN Isoform Lamin C of Prelamin-A/C OS=Homo sapiens GN=LMNA 0.925109 12.4106 0.02908 -14.9676 0.443806 14.968 0 0 0.608832 1.924 0.00994839 62.547 0.925109 12.4106 0.126646 36.609 0.241736 -0.556647 0.734431 0.55665 1 S RLRLSPSPTSQRS NEK6;Proline-directed 0.05 0.00994839 62.547 _LRLSPpSPTSQR_ LRLS(0.053)PS(0.925)PT(0.021)SQR LRLS(-12.41)PS(12.41)PT(-16.35)S(-34.14)QR 6 2 661.33483 0.32582 544080 0 0 0 491360 0 52719 0 383 284 22 22 5283 6011 51240 31396 Mix4_TiO2_1_3 2588 51239 31395 Mix4_InSol_Tio2_Reinj_1 3544 P02545;P02545-3;P02545-2 P02545 P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN=LMNA PE=1 SV=1;>sp|P02545-3|LMNA_HUMAN Isoform Lamin ADelta10 of Prelamin-A/C OS=Homo sapiens GN=LMNA;>sp|P02545-2|LMNA_HUMAN Isoform Lamin C of Prelamin-A/C OS=Homo sapiens GN=LMNA 0.955105 14.4888 0.955105 14.4888 0.00951993 73.739 0 0 0 0 0 0 0.874998 9.49865 0.00332409 80.085 1 S ASSTPLSPTRITR CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00332409 80.085 _SGAQASSTPLpSPTR_ SGAQASST(0.034)PLS(0.955)PT(0.011)R S(-73.74)GAQAS(-69.73)S(-43.07)T(-14.49)PLS(14.49)PT(-19.44)R 11 2 720.32995 -0.013044 152980 88941 0 0 0 0 0 64039 384 288 662 662 46 57 498 314 Mix4_TiO2_Reinj_1_3 4611 498 314 Mix4_TiO2_Reinj_1_3 4611 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.983295 17.785 0.982463 17.5783 0.0175359 66.224 0.983295 17.785 0.00110572 88.307 0 0 0 0 1 S ACTLTTSPRLPVF CDK1;CK1;NEK6;Proline-directed 0.0057 0.00110572 88.307 _AAHTEDINACTLTTpSPR_ AAHTEDINACTLTT(0.016)S(0.983)PR AAHT(-88.31)EDINACT(-64.93)LT(-34.74)T(-17.79)S(17.79)PR 15 3 646.61894 -0.0234 429990 84998 0 0 344990 0 0 0 385 288 29 29 753 859 7285 4308 Mix4_TiO2_1_3 7305 7287 4310 Mix4_TiO2_Reinj_1_3 7905 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.769168 5.64368 0.769168 5.64368 2.55584E-11 128.75 0.583675 1.47935 1.38069E-32 183.36 1 S DGSSCISPTIVQQ CK1;Proline-directed 0.05 1.38069E-32 183.36 _DAVFDGSSCIpSPTIVQQFGYQR_ DAVFDGSS(0.021)CIS(0.769)PT(0.21)IVQQFGYQR DAVFDGS(-32.14)S(-15.71)CIS(5.64)PT(-5.64)IVQQFGY(-99.92)QR 11 3 852.38059 0.075778 930220 572140 0 0 358070 0 0 0 386 288 43 43 4807 5457 45799 28004 Mix4_TiO2_1_3 1914 45799 28004 Mix4_TiO2_1_3 1914 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.998606 28.7592 0.998606 28.7592 0.011371 71.63 0.98565 21.379 0.331156 26.04 0 0 0.953021 16.0823 0.564734 16.082 1 S GYQRRASDDGKLT CAMK2;PKA 0.004788 0.011371 71.63 _RApSDDGKLTDPSK_ RAS(0.999)DDGKLT(0.001)DPSK RAS(28.76)DDGKLT(-28.76)DPS(-41.88)K 3 2 735.33523 -0.16855 1087200 86021 0 0 946060 0 0 55128 387 288 315 315 5350 6091 51968 31819 Mix4_TiO2_Reinj_1_3 5901 51966 31817 Mix4_TiO2_1_3 5234 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.422636 0.682486 0.020438 -16.8058 2.4306E-35 184.15 0.422636 0.682486 2.00825E-07 102.77 0 0 7.48368E-05 -41.2262 0.00539154 75.957 1 S SPSALSSSPNNLS CK1 0.143 2.4306E-35 184.15 _SHSESASPSALSpSSPNNLSPTGWSQPK_ SHSESASPS(0.005)ALS(0.019)S(0.423)S(0.361)PNNLS(0.189)PT(0.004)GWSQPK S(-50.48)HS(-50.2)ES(-50.2)AS(-37.59)PS(-19.67)ALS(-13.54)S(0.68)S(-0.68)PNNLS(-3.5)PT(-20.37)GWS(-35.51)QPK 13 3 940.75393 0.1312 0 0 0 0 0 0 0 0 388 288 316 316 5350 6091 51966 31817 Mix4_TiO2_1_3 5234 51966 31817 Mix4_TiO2_1_3 5234 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.97953 16.8058 0.97953 16.8058 2.4306E-35 184.15 0.361175 -0.682486 2.00825E-07 102.77 0 0 0.00131769 -28.7692 0.00539154 75.957 1 S PSALSSSPNNLSP NEK6;Polo box;Proline-directed 0.00405 2.4306E-35 184.15 _SHSESASPSALSSpSPNNLSPTGWSQPK_ SHSESASPSALSS(0.02)S(0.98)PNNLSPTGWSQPK S(-120.96)HS(-113.78)ES(-113.78)AS(-100.97)PS(-79.25)ALS(-49.03)S(-16.81)S(16.81)PNNLS(-47)PT(-86.43)GWS(-115.65)QPK 14 3 940.75393 -0.19874 240760 240760 0 0 0 0 0 0 389 288 321 321 5350 6091 51965 31815 Mix4_InSol_Tio2_Reinj_1 6203 51966 31817 Mix4_TiO2_1_3 5234 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.992512 22.3547 1.95593E-05 -46.9967 2.4306E-35 184.15 0.498366 0 2.00825E-07 102.77 0 0 0.992512 22.3547 0.00539154 75.957 1 S SSPNNLSPTGWSQ Proline-directed 0.05 2.4306E-35 184.15 _SHSESASPSALSSSPNNLpSPTGWSQPK_ SHSESASPSALSSS(0.001)PNNLS(0.993)PT(0.006)GWSQPK S(-75.96)HS(-75.96)ES(-75.96)AS(-73.32)PS(-63.7)ALS(-47.11)S(-41.23)S(-28.77)PNNLS(22.35)PT(-22.35)GWS(-35.13)QPK 19 3 940.75393 0.76499 92905 0 0 0 0 0 0 92905 390 288 257 257 5805 6616;6617 57219 34872 Mix4_InSol_TiO2_1 6354 57219 34872 Mix4_InSol_TiO2_1 6354 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.676032 6.57777 0.11175 -8.2872 0.0198481 60.893 0 0 0.0691144 -9.67952 0.109975 49.254 0.676032 6.57777 0.013915 66.781 0.277181 -0.632366 0.471473 33.337 1 S LSQRQRSTSTPNV CAMK2 0.042 0.013915 66.781 _pSTSTPNVHMVSTTLPVDSR_ S(0.676)T(0.149)S(0.149)T(0.027)PNVHMVSTTLPVDSR S(6.58)T(-6.58)S(-6.58)T(-14.04)PNVHMVS(-62.49)T(-66.78)T(-66.78)LPVDS(-66.78)R 1 2 1054.9877 0.080563 191970 0 0 0 0 0 191970 0 391 288 259 259 5805 6616;6617 57209 34869 Mix4_TiO2_1_3 4450 57219 34872 Mix4_InSol_TiO2_1 6354 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.753299 8.2872 0.753299 8.2872 0.0198481 60.893 0 0 0.641978 4.92055 0.109975 49.254 0.280279 0 0.013915 66.781 0.449575 0 0.471473 33.337 1 S QRQRSTSTPNVHM 14-3-3 binding;CAMK2;PKA/AKT 0.0001701 0.013915 66.781 _STpSTPNVHM(ox)VSTTLPVDSR_ S(0.112)T(0.112)S(0.753)T(0.023)PNVHMVSTTLPVDSR S(-8.29)T(-8.29)S(8.29)T(-15.16)PNVHMVS(-35.62)T(-51.64)T(-51.03)LPVDS(-60.89)R 3 3 708.99256 -0.51463 1281500 299360 0 0 982150 0 0 0 392 288 233 233 6808 7791 69079 42356 Mix4_TiO2_Reinj_1_3 6441 69079 42356 Mix4_TiO2_Reinj_1_3 6441 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.789497 7.32061 0.395082 0 0.0121851 66.968 0.789497 7.32061 0.00907476 70.357 1 S SSQHRYSTPHAFT PKA 0.042 0.00907476 70.357 _YpSTPHAFTFNTSSPSSEGSLSQR_ Y(0.053)S(0.789)T(0.146)PHAFT(0.01)FNT(0.001)SSPSSEGSLSQR Y(-11.7)S(7.32)T(-7.32)PHAFT(-18.91)FNT(-31.75)S(-37.88)S(-57.72)PS(-70.36)S(-70.36)EGS(-70.36)LS(-70.36)QR 2 3 856.70614 0.19115 498890 0 0 0 498890 0 0 0 393 291 13 13 5134 5840 49649 30337 Mix4_TiO2_Reinj_1_6 6320 49648 30336 Mix4_TiO2_1_6 5607 P04183 P04183 P04183 >sp|P04183|KITH_HUMAN Thymidine kinase, cytosolic OS=Homo sapiens GN=TK1 PE=1 SV=2 0.951499 12.9269 0.424986 -1.31304 8.79867E-05 100.08 0.951499 12.9269 0.0195504 64.959 1 S PTVLPGSPSKTRG CDK1;CDK2;ERK/MAPK;NEK6;Proline-directed 0.0025 8.79867E-05 100.08 _(ac)SCINLPTVLPGpSPSK_ SCINLPTVLPGS(0.951)PS(0.048)K S(-64.96)CINLPT(-54.68)VLPGS(12.93)PS(-12.93)K 12 2 846.40734 0.23261 151190 0 0 0 151190 0 0 0 394 291 15 15 5134 5840 49648 30336 Mix4_TiO2_1_6 5607 49648 30336 Mix4_TiO2_1_6 5607 P04183 P04183 P04183 >sp|P04183|KITH_HUMAN Thymidine kinase, cytosolic OS=Homo sapiens GN=TK1 PE=1 SV=2 0.575014 1.31304 0.575014 1.31304 8.79867E-05 100.08 0.0484979 -12.9269 0.0195504 64.959 1 S VLPGSPSKTRGQI 8.79867E-05 100.08 _(ac)SCINLPTVLPGSPpSK_ SCINLPTVLPGS(0.425)PS(0.575)K S(-100.08)CINLPT(-75.51)VLPGS(-1.31)PS(1.31)K 14 2 846.40734 -0.12716 58471 58471 0 0 0 0 0 0 395 293 19 19 5297 6030 51428 31496 Mix4_InSol_TiO2_1 6161 51429 31497 Mix4_InSol_Tio2_Reinj_1 6095 P04264;CON__P04264 P04264 P04264 67 kDa cytokeratin;Cytokeratin-1;Hair alpha protein;Keratin, type II cytoskeletal 1;Keratin-1;Type-II keratin Kb1 KRT1;KRTA >sp|P04264|K2C1_HUMAN Keratin, type II cytoskeletal 1 OS=Homo sapiens GN=KRT1 PE=1 SV=6;>P04264 SWISS-PROT:P04264 Tax_Id=9606 Gene_Symbol=KRT1 Keratin, type II cytoskeletal 1 P04264 0.637558 2.62112 0 0 0 0 0.637558 2.62112 0.00170375 82.579 0.0228415 -16.3123 4.91584E-09 123.97 1 S SGGGFSSGSAGII 4.91584E-09 123.97 _SGGGFSpSGSAGIINYQR_ SGGGFS(0.014)S(0.638)GS(0.349)AGIINYQR S(-33.8)GGGFS(-16.74)S(2.62)GS(-2.62)AGIINY(-64.17)QR 7 2 869.38324 -0.21329 72733 0.75695 0 0 0 0 0 72733 0 + 396 293 21 21 Phosphoserine 5297 6030 51429 31497 Mix4_InSol_Tio2_Reinj_1 6095 51429 31497 Mix4_InSol_Tio2_Reinj_1 6095 P04264;CON__P04264 P04264 P04264 67 kDa cytokeratin;Cytokeratin-1;Hair alpha protein;Keratin, type II cytoskeletal 1;Keratin-1;Type-II keratin Kb1 KRT1;KRTA >sp|P04264|K2C1_HUMAN Keratin, type II cytoskeletal 1 OS=Homo sapiens GN=KRT1 PE=1 SV=6;>P04264 SWISS-PROT:P04264 Tax_Id=9606 Gene_Symbol=KRT1 Keratin, type II cytoskeletal 1 P04264 0.977137 16.3123 0 0 0 0 0.348665 -2.62112 0.00170375 82.579 0.977137 16.3123 4.91584E-09 123.97 1 S GGFSSGSAGIINY CK1 0.081 4.91584E-09 123.97 _SGGGFSSGpSAGIINYQR_ SGGGFSS(0.023)GS(0.977)AGIINYQR S(-70.11)GGGFS(-46.55)S(-16.31)GS(16.31)AGIINY(-98.96)QR 9 2 869.38324 0.067691 52661 0.54806 0 0 0 0 0 0 52661 + 397 297 315 315 340;4800 387;5450 3132 1899 Mix4_TiO2_1_2 1766 3133 1901 Mix4_TiO2_1_4 2083 P04637;P04637-2 P04637 P04637 >sp|P04637|P53_HUMAN Cellular tumor antigen p53 OS=Homo sapiens GN=TP53 PE=1 SV=4;>sp|P04637-2|P53_HUMAN Isoform I9RET of Cellular tumor antigen p53 OS=Homo sapiens GN=TP53 0.98312 19.6299 0.98312 19.6299 0.018049 63.697 0.895471 11.3414 0.0441706 53.929 0.495337 2.51015 0.674767 12.322 0.667971 6.66934 0.690766 11.775 1 S PNNTSSSPQPKKK Polo box;Proline-directed 0.00405 0.018049 63.697 _ALPNNTSSpSPQPK_ ALPNNT(0.003)S(0.011)S(0.003)S(0.983)PQPK ALPNNT(-24.79)S(-19.63)S(-25.29)S(19.63)PQPK 9 2 710.82704 0.11459 1063500 253610 0 0 652520 0 0 157410 398 298 82 82 4639 5265 43959 26941 Mix4_InSol_Tio2_Reinj_1 4865 43957 26939 Mix4_InSol_TiO2_1 4935 P04792 P04792 P04792 >sp|P04792|HSPB1_HUMAN Heat shock protein beta-1 OS=Homo sapiens GN=HSPB1 PE=1 SV=2 0.997692 26.3672 0.996969 25.1891 0.00622156 62.669 0.702218 6.08759 0.626074 7.4986 0.978289 16.6397 0.162509 32.892 0 0 0.978268 16.5433 0.00544715 65.057 0.997692 26.3672 0.0142852 57.826 1 S ALSRQLSSGVSEI CAMK2;CHK1;CHK1/2;CK1;GSK3;PKD 0.003192 0.00544715 65.057 _QLpSSGVSEIR_ QLS(0.998)S(0.002)GVSEIR QLS(26.37)S(-26.37)GVS(-52.89)EIR 3 2 578.27391 0.41576 5494200 1016900 43572 0 1941700 0 1552000 940080 399 298 83 83 4639 5265 43958 26940 Mix4_InSol_TiO2_3 2698 43957 26939 Mix4_InSol_TiO2_1 4935 P04792 P04792 P04792 >sp|P04792|HSPB1_HUMAN Heat shock protein beta-1 OS=Homo sapiens GN=HSPB1 PE=1 SV=2 0.376423 0 0.0233036 -16.2144 0.00622156 62.669 0.172867 -6.08759 0.626074 7.4986 0.0212081 -16.6397 0.162509 32.892 0 0 0.376423 0 0.00544715 65.057 0.00230292 -26.3672 0.0142852 57.826 1 S LSRQLSSGVSEIR 0.00544715 65.057 _QLpSSGVSEIR_ QLS(0.376)S(0.376)GVS(0.247)EIR QLS(0)S(0)GVS(-1.83)EIR 4 2 578.27391 -0.28278 0 0 0 0 0 0 0 0 400 308;309 101;102 101 3002 3413;3414;3415;3416 28723 17889 Mix4_TiO2_Reinj_1_6 7269 28717 17886 Mix4_TiO2_Reinj_1_2 6818 P05386;P05387 P05386;P05387 P05386 >sp|P05386|RLA1_HUMAN 60S acidic ribosomal protein P1 OS=Homo sapiens GN=RPLP1 PE=1 SV=1;>sp|P05387|RLA2_HUMAN 60S acidic ribosomal protein P2 OS=Homo sapiens GN=RPLP2 PE=1 SV=1 1 42.4817 1 57.4296 0.0438109 57.43 1 42.4817 0.000389275 95.17 0.00234712 -26.2844 0.00655196 75.661 0.000126624 -38.9743 3.84655E-06 110.83 2 S DEKKEESEESDDD;EAKKEESEESDDD 0.000389275 95.17 _KEEpSEEpSDDDMGFGLFD_ KEES(1)EES(1)DDDMGFGLFD KEES(42.48)EES(42.48)DDDMGFGLFD 4 2 1055.3496 0.36379 229370 38644 0 0 190720 0 0 0 401 308;309 104;105 104 3002 3413;3414;3415;3416 28712 17883 Mix4_InSol_Tio2_Reinj_1 8576 28712 17883 Mix4_InSol_Tio2_Reinj_1 8576 P05386;P05387 P05386;P05387 P05386 >sp|P05386|RLA1_HUMAN 60S acidic ribosomal protein P1 OS=Homo sapiens GN=RPLP1 PE=1 SV=1;>sp|P05387|RLA2_HUMAN 60S acidic ribosomal protein P2 OS=Homo sapiens GN=RPLP2 PE=1 SV=1 0.999873 38.9743 1 57.4296 0.0438109 57.43 0.998883 29.5149 0.114644 47.15 0.997653 26.2844 0.00655196 75.661 0.999873 38.9743 3.84655E-06 110.83 1 S KEESEESDDDMGF CK1;CK2 0.081 3.84655E-06 110.83 _KEESEEpSDDDMGFGLFD_ KEESEES(1)DDDMGFGLFD KEES(-38.97)EES(38.97)DDDMGFGLFD 7 2 1015.3665 -0.34087 189980 0 0 0 39571 0 49528 100880 402 310 304 304 1505;6376 1689;1690;1691;7293;7294;7295 64429 39546 Mix4_TiO2_Reinj_1_4 8490 13929 8480 Mix4_TiO2_Reinj_1_2 7099 P05388;Q8NHW5 P05388 P05388 >sp|P05388|RLA0_HUMAN 60S acidic ribosomal protein P0 OS=Homo sapiens GN=RPLP0 PE=1 SV=1;>sp|Q8NHW5|RLA0L_HUMAN 60S acidic ribosomal protein P0-like OS=Homo sapiens PE=1 SV=1 1 126.788 1 116.004 1.39775E-10 125.23 1 126.788 7.91893E-26 203.34 2 S VEAKEESEESDED 7.91893E-26 203.34 _VEAKEEpSEEpSDEDMGFGLFD_ VEAKEES(1)EES(1)DEDMGFGLFD VEAKEES(126.79)EES(126.79)DEDMGFGLFD 7 2 1211.9315 -0.41141 7136400 1233800 0 0 5902600 0 0 0 403 310 307 307 1505;6376 1689;1690;1691;7293;7294;7295 64408 39514 Mix4_TiO2_Reinj_1_2 6654 64408 39514 Mix4_TiO2_Reinj_1_2 6654 P05388;Q8NHW5 P05388 P05388 >sp|P05388|RLA0_HUMAN 60S acidic ribosomal protein P0 OS=Homo sapiens GN=RPLP0 PE=1 SV=1;>sp|Q8NHW5|RLA0L_HUMAN 60S acidic ribosomal protein P0-like OS=Homo sapiens PE=1 SV=1 0.999787 36.7063 0.994128 22.2865 2.03293E-10 119.71 0.999787 36.7063 5.64029E-12 136.9 1 S KEESEESDEDMGF CK1;CK2 0.081 5.64029E-12 136.9 _VEAKEESEEpSDEDM(ox)GFGLFD_ VEAKEESEES(1)DEDMGFGLFD VEAKEES(-36.71)EES(36.71)DEDMGFGLFD 10 2 1179.9458 -0.092482 367000 86722 0 0 280280 0 0 0 404 311 100 100 3310 3746 31227 19337 Mix4_TiO2_Reinj_1_6 3461 31226 19336 Mix4_TiO2_Reinj_1_4 4016 P17535;P05412 P17535 P17535 >sp|P17535|JUND_HUMAN Transcription factor jun-D OS=Homo sapiens GN=JUND PE=1 SV=3;>sp|P05412|JUN_HUMAN Transcription factor AP-1 OS=Homo sapiens GN=JUN PE=1 SV=2 1 16.9167 1 59.9591 0.0236272 59.959 0 0 1 16.9167 0.0188621 63.854 0 0 0 0 1 S GLLKLASPELERL CHK1;PKD;Proline-directed 0.020748 0.0188621 63.854 _LApSPELER_ LAS(1)PELER LAS(16.92)PELER 3 2 497.73389 0.47805 160630 29599 0 0 131030 0 0 0 405 312 366 366 1951 2209 17875 10688 Mix4_InSol_TiO2_1 3513 17875 10688 Mix4_InSol_TiO2_1 3513 P05455 P05455 P05455 >sp|P05455|LA_HUMAN Lupus La protein OS=Homo sapiens GN=SSB PE=1 SV=2 1 78.368 1 78.368 0.00155719 78.368 0 0 1 S KKTKFASDDEHDE CK1;CK2 0.117 0.00155719 78.368 _FApSDDEHDEHDENGATGPVKR_ FAS(1)DDEHDEHDENGATGPVKR FAS(78.37)DDEHDEHDENGAT(-78.37)GPVKR 3 3 802.65918 -0.78564 116860 0 0 0 0 0 116860 0 406 315 21 21 891;3759 1005;4240 8501 5163 Mix4_TiO2_1_4 2475 35502 21931 Mix4_TiO2_Reinj_1_4 3530 P06241;P06241-2;P06241-3 P06241 P06241 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN PE=1 SV=3;>sp|P06241-2|FYN_HUMAN Isoform T of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN;>sp|P06241-3|FYN_HUMAN Isoform 3 of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN 1 79.7582 1 79.7582 1.3328E-05 99.44 0 0 0.999999 63.6516 1.45408E-12 149.22 0.999996 57.3874 0.0071058 75.614 0.999749 37.5451 0.0512595 56.252 1 S TEERDGSLNQSSG CAMK2;GSK3;PLK1 0.033462 1.45408E-12 149.22 _DGpSLNQSSGYR_ DGS(1)LNQSSGYR DGS(79.76)LNQS(-79.76)S(-86)GY(-86)R 3 2 632.25371 -0.26975 4173700 111.11 625830 0 0 2462900 0 781800 303140 407 315;332 186;195 195 2122 2406 19576 11950 Mix4_TiO2_1_4 4861 19577 11951 Mix4_TiO2_Reinj_1_4 4646 P06241;P06241-2;P06241-3;P09769;P07947 P06241;P07947 P07947 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN PE=1 SV=3;>sp|P06241-2|FYN_HUMAN Isoform T of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN;>sp|P06241-3|FYN_HUMAN Isoform 3 of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN; 0.846314 8.09458 0.846314 8.09458 0.105957 47.298 0.00571415 -22.4056 0.0234921 59.98 1 S TTKGAYSLSIRDW 0.0234921 59.98 _GAYpSLSIR_ GAY(0.022)S(0.846)LS(0.131)IR GAY(-15.76)S(8.09)LS(-8.09)IR 4 2 473.72332 0.62341 8269.3 8269.3 0 0 0 0 0 0 408 316 795 795 2038;5600 2311;6382 18654 11381 Mix4_TiO2_Reinj_1_5 4877 18650 11372 Mix4_TiO2_1_5 3832 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.999956 43.5437 0.995725 23.6721 0.112055 52.712 0.999956 43.5437 0.116465 51.938 1 S PYKFPSSPLRIPG CDK1;CDK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.112055 52.712 _FPSpSPLR_ FPSS(1)PLR FPS(-43.54)S(43.54)PLR 4 2 442.20731 -0.018629 174770 25827 0 0 148940 0 0 0 409 316 811 811 2858 3255;3256 27262 17035 Mix4_TiO2_1_5 5936 27262 17035 Mix4_TiO2_1_5 5936 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.99692 25.1016 0.99692 25.1016 3.5531E-12 138.49 0.99079 20.3806 0.146457 41.649 2 S YISPLKSPYKISE CDK1;CDK2;CK1;Proline-directed 0.0057 3.5531E-12 138.49 _IPGGNIYIpSPLKpSPYK_ IPGGNIYIS(1)PLKS(0.997)PY(0.003)K IPGGNIY(-60.73)IS(53.82)PLKS(25.1)PY(-25.1)K 13 2 953.95941 0.27121 779560 257100 0 0 522450 0 0 0 410 316 788 788 5600 6382 54782 33541 Mix4_TiO2_Reinj_1_5 5945 54782 33541 Mix4_TiO2_Reinj_1_5 5945 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.998981 32.4378 0.985972 16.8869 0.0365895 52.612 0.998981 32.4378 0.0120338 59.895 2 S IPHIPRSPYKFPS CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0120338 59.895 _pSPYKFPSpSPLR_ S(0.999)PY(0.001)KFPS(0.107)S(0.893)PLR S(32.44)PY(-32.44)KFPS(-9.23)S(9.23)PLR 1 2 719.81202 1.9995 358590 75008 0 0 283580 0 0 0 411 316 347 347 6079 6934 60042 36398 Mix4_TiO2_2_2 4742 60044 36400 Mix4_TiO2_Reinj_1_1 5170 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.70173 6.61307 0.326356 1.62729 0.114801 47.104 0.70173 6.61307 0.540668 28.574 0.373854 -0.547665 0.00539632 76.651 0 0 0 0 1 S KTLQTDSIDSFET 0.00539632 76.651 _TLQTDpSIDSFETQRTPR_ T(0.002)LQT(0.013)DS(0.702)IDS(0.059)FET(0.072)QRT(0.153)PR T(-26.44)LQT(-17.42)DS(6.61)IDS(-10.78)FET(-9.87)QRT(-6.61)PR 6 3 692.31955 0.23821 131480 0 131480 0 0 0 0 0 412 316 780 780 6111 6975 60388 36532 Mix4_TiO2_Reinj_1_5 7608 60389 36533 Mix4_TiO2_Reinj_1_5 7610 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.438634 0 0 0 0.438634 0 4.8075E-07 108.66 1 S TRPPTLSPIPHIP Proline-directed 0.05 4.8075E-07 108.66 _TNILQYASTRPPpTLSPIPHIPR_ T(0.003)NILQY(0.012)AS(0.054)T(0.054)RPPT(0.439)LS(0.439)PIPHIPR T(-21.92)NILQY(-15.73)AS(-9.09)T(-9.09)RPPT(0)LS(0)PIPHIPR 15 4 638.84008 -0.15414 0 0 0 0 0 0 0 0 413 317 2 2 5149 5863 49920 30520 Mix4_InSol_Tio2_Reinj_1 4670 49920 30520 Mix4_InSol_Tio2_Reinj_1 4670 P06454;P06454-2 P06454 P06454 >sp|P06454|PTMA_HUMAN Prothymosin alpha OS=Homo sapiens GN=PTMA PE=1 SV=2;>sp|P06454-2|PTMA_HUMAN Isoform 2 of Prothymosin alpha OS=Homo sapiens GN=PTMA 0.999985 55.1335 0 0 0 0 0.999985 55.1335 0.0452566 55.134 1 S _____MSDAAVDT 0.0452566 55.134 _(ac)pSDAAVDTSSEITTK_ S(1)DAAVDTSSEITTK S(55.13)DAAVDT(-55.13)S(-55.13)S(-55.13)EIT(-55.13)T(-55.13)K 1 2 773.82964 0.66972 75757 3.724 0 0 0 0 0 0 75757 414 321 125 125 665 765 6390 3788 Mix4_TiO2_Reinj_1_6 5056 6390 3788 Mix4_TiO2_Reinj_1_6 5056 P06748;P06748-2 P06748 P06748 >sp|P06748|NPM_HUMAN Nucleophosmin OS=Homo sapiens GN=NPM1 PE=1 SV=2;>sp|P06748-2|NPM_HUMAN Isoform 2 of Nucleophosmin OS=Homo sapiens GN=NPM1 1 124.78 1 124.78 4.44447E-13 132.19 1 S VEEDAESEDEEEE CK2 0.117 4.44447E-13 132.19 _CGSGPVHISGQHLVAVEEDAEpSEDEEEEDVK_ CGSGPVHISGQHLVAVEEDAES(1)EDEEEEDVK CGS(-130.42)GPVHIS(-124.78)GQHLVAVEEDAES(124.78)EDEEEEDVK 22 3 1154.1505 -0.34755 68654 0 0 0 68654 0 0 0 415 329 880 880 1936;5998 2188;2189;6838 17754 10613 Mix4_TiO2_1_5 4760 17755 10616 Mix4_TiO2_Reinj_1_5 5507 P07814 P07814 P07814 >sp|P07814|SYEP_HUMAN Bifunctional aminoacyl-tRNA synthetase OS=Homo sapiens GN=EPRS PE=1 SV=5 0.836761 7.16284 0.836761 7.16284 3.28329E-06 103.52 0.0111253 -14.784 0.000576248 89.057 0.0213078 -14.2506 2.51174E-06 106.95 0.0018457 -23.7967 0.170467 41.814 0.111921 -5.66879 0.0120601 77.85 0.0372866 -10.679 0.000331845 90.437 2 S PGQPPLSQSSDSS 6.78195E-07 115.1 _EYIPGQPPLpSQSSDSpSPTR_ EYIPGQPPLS(0.837)QS(0.162)S(0.002)DS(0.033)S(0.873)PT(0.093)R EY(-103.52)IPGQPPLS(7.16)QS(-7.16)S(-27.34)DS(-14.23)S(9.74)PT(-9.74)R 10 2 1103.4587 -0.075494 233420 3.5046 233420 0 0 0 0 0 0 416 329 882 882 1936;5998 2188;2189;6838 17755 10616 Mix4_TiO2_Reinj_1_5 5507 17755 10616 Mix4_TiO2_Reinj_1_5 5507 P07814 P07814 P07814 >sp|P07814|SYEP_HUMAN Bifunctional aminoacyl-tRNA synthetase OS=Homo sapiens GN=EPRS PE=1 SV=5 0.841342 7.77241 0.161676 -7.16284 3.28329E-06 103.52 0.334742 0.819494 0.000576248 89.057 0.841342 7.77241 6.78195E-07 115.1 0.00726402 -17.8466 0.170467 41.814 0.0476155 -12.0078 0.0120601 77.85 0.435962 3.14116 0.000331845 90.437 2 S QPPLSQSSDSSPT GSK3;NEK6 0.076 6.78195E-07 115.1 _EYIPGQPPLSQpSSDSpSPTR_ EYIPGQPPLS(0.018)QS(0.841)S(0.142)DS(0.028)S(0.956)PT(0.015)R EY(-115.1)IPGQPPLS(-16.67)QS(7.77)S(-7.77)DS(-15.45)S(15.45)PT(-17.92)R 12 2 1103.4587 0.37036 996380 14.959 0 0 0 996380 0 0 0 417 329 885 885 1936;5998 2188;2189;6838 59221 35981 Mix4_InSol_TiO2_1 6050 17737 10598 Mix4_TiO2_1_5 4611 P07814 P07814 P07814 >sp|P07814|SYEP_HUMAN Bifunctional aminoacyl-tRNA synthetase OS=Homo sapiens GN=EPRS PE=1 SV=5 0.756004 10.7624 0.15527 -6.75528 1.4944E-15 142.65 0.277179 -0.819494 0.000576248 89.057 0.147662 -5.84333 2.51174E-06 106.95 0.442418 0 0.170467 41.814 0.756004 10.7624 0.0120601 77.85 0.567287 6.29403 0.000331845 90.437 1 S LSQSSDSSPTRNS CK1 0.081 1.4944E-15 142.65 _TGKEYIPGQPPLSQSSDpSSPTRNSEPAGLETPEAK_ TGKEYIPGQPPLS(0.048)QS(0.048)S(0.048)DS(0.756)S(0.063)PT(0.018)RNS(0.02)EPAGLETPEAK T(-42.02)GKEY(-42.02)IPGQPPLS(-12.01)QS(-12.01)S(-12.01)DS(10.76)S(-10.76)PT(-16.25)RNS(-15.86)EPAGLET(-41.59)PEAK 18 4 934.69009 -0.27734 1102800 16.557 0 0 0 0 0 667820 434950 418 329 886 886 1936;5998 2188;2189;6838 17738 10600 Mix4_TiO2_1_6 3844 17737 10598 Mix4_TiO2_1_5 4611 P07814 P07814 P07814 >sp|P07814|SYEP_HUMAN Bifunctional aminoacyl-tRNA synthetase OS=Homo sapiens GN=EPRS PE=1 SV=5 0.918156 13.6722 0.918156 13.6722 1.4944E-15 142.65 0.800747 9.12243 0.000576248 89.057 0.86867 9.70826 2.51174E-06 106.95 0.442418 0 0.170467 41.814 0.342824 -2.02593 0.0120601 77.85 0.887657 12.2787 0.000331845 90.437 1 S SQSSDSSPTRNSE CDK1;CDK2;CK1;Polo box;Proline-directed 0.00405 1.4944E-15 142.65 _EYIPGQPPLSQSSDSpSPTR_ EYIPGQPPLS(0.002)QS(0.003)SDS(0.039)S(0.918)PT(0.037)R EY(-84.08)IPGQPPLS(-26.09)QS(-25.45)S(-33.47)DS(-13.67)S(13.67)PT(-13.93)R 16 2 1063.4755 0.35408 22340000 335.42 5100000 293720 0 16419000 0 0 528220 419 330 353 353 943;944 1063;1064 8958 5470 Mix4_TiO2_Reinj_1_3 2219 8952 5468 Mix4_TiO2_Reinj_1_3 2025 P07900-2;P07900 P07900-2 P07900-2 >sp|P07900-2|HS90A_HUMAN Isoform HSP90AA1-2 of Heat shock protein HSP 90-alpha OS=Homo sapiens GN=HSP90AA1;>sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha OS=Homo sapiens GN=HSP90AA1 PE=1 SV=5 1 27.8175 1 139.306 1.26767E-05 139.31 1 27.8175 6.75054E-13 179 1 S ERDKEVSDDEAEE CK2 0.117 6.75054E-13 179 _DKEVpSDDEAEEKEDK_ DKEVS(1)DDEAEEKEDK DKEVS(27.82)DDEAEEKEDK 5 3 615.91397 -0.26458 429440 64726 0 0 364710 0 0 0 420 330 385 385 1802;1803 2033;2034 16565 9986 Mix4_TiO2_Reinj_1_3 4046 16565 9986 Mix4_TiO2_Reinj_1_3 4046 P07900-2;P07900 P07900-2 P07900-2 >sp|P07900-2|HS90A_HUMAN Isoform HSP90AA1-2 of Heat shock protein HSP 90-alpha OS=Homo sapiens GN=HSP90AA1;>sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha OS=Homo sapiens GN=HSP90AA1 PE=1 SV=5 1 106.052 0.999991 50.234 0.0486743 56.786 1 106.052 5.38966E-22 168.9 1 S EIEDVGSDEEEEK CK2 0.117 5.38966E-22 168.9 _ESEDKPEIEDVGpSDEEEEKK_ ESEDKPEIEDVGS(1)DEEEEKK ES(-106.05)EDKPEIEDVGS(106.05)DEEEEKK 13 3 800.99865 0.4426 2540400 279480 0 0 2260900 0 0 0 421 331 299 299 773;1378 880;1549 7446 4394 Mix4_TiO2_1_4 2034 7448 4396 Mix4_TiO2_Reinj_1_4 2447 P07910;P07910-2;P07910-4;P07910-3 P07910 P07910 >sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4;>sp|P07910-2|HNRPC_HUMAN Isoform C1 of Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC;>sp|P07910-4|HNRPC_HUMAN Isoform 4 of 0.999962 44.1776 0.999962 44.1776 0.199357 44.178 0.998401 27.9557 0.00722327 72.065 0.988797 19.4577 0.888339 19.458 0.998401 27.9552 0.480623 31.556 1 S GEDDRDSANGEDD PKA 0.042 0.00722327 72.065 _DDEKEAEEGEDDRDpSANGEDDS_ DDEKEAEEGEDDRDS(1)ANGEDDS DDEKEAEEGEDDRDS(44.18)ANGEDDS(-44.18) 15 3 836.2877 -2.9993 481010 110610 0 0 342370 0 12731 15296 422 331 253 253 3845 4348 36428 22481 Mix4_TiO2_1_4 4639 36429 22482 Mix4_TiO2_Reinj_1_4 5262 P07910;P07910-2;P07910-4;P07910-3 P07910 P07910 >sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4;>sp|P07910-2|HNRPC_HUMAN Isoform C1 of Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC;>sp|P07910-4|HNRPC_HUMAN Isoform 4 of 0.645625 2.60517 0.645625 2.60517 0.000406032 81.668 0.000112642 -39.4825 2.87415E-13 137.12 1 S TNVKMESEGGADD 2.87415E-13 137.12 _M(ox)EpSEGGADDSAEEGDLLDDDDNEDR_ MES(0.646)EGGADDS(0.354)AEEGDLLDDDDNEDR MES(2.61)EGGADDS(-2.61)AEEGDLLDDDDNEDR 3 2 1397.9851 0.57051 153170 153170 0 0 0 0 0 0 423 331 260 260 3845 4348 36429 22482 Mix4_TiO2_Reinj_1_4 5262 36429 22482 Mix4_TiO2_Reinj_1_4 5262 P07910;P07910-2;P07910-4;P07910-3 P07910 P07910 >sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4;>sp|P07910-2|HNRPC_HUMAN Isoform C1 of Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC;>sp|P07910-4|HNRPC_HUMAN Isoform 4 of 0.999887 39.4825 0.354375 -2.60517 0.000406032 81.668 0.999887 39.4825 2.87415E-13 137.12 1 S EGGADDSAEEGDL CK2 0.117 2.87415E-13 137.12 _M(ox)ESEGGADDpSAEEGDLLDDDDNEDR_ MESEGGADDS(1)AEEGDLLDDDDNEDR MES(-39.48)EGGADDS(39.48)AEEGDLLDDDDNEDR 10 3 932.32583 0.39424 405510 0 0 0 405510 0 0 0 424 331 233 233 3971;3972;4480 4523;4526;5092 37571 23076 Mix4_TiO2_Reinj_1_4 1626 37570 23073 Mix4_TiO2_1_4 1222 P07910;P07910-2;P07910-4;P07910-3 P07910 P07910 >sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC PE=1 SV=4;>sp|P07910-2|HNRPC_HUMAN Isoform C1 of Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens GN=HNRNPC;>sp|P07910-4|HNRPC_HUMAN Isoform 4 of 1 72.0205 1 74.1636 4.98005E-10 155.9 0 0 1 72.0205 1.8227E-09 153.75 0.999998 56.7632 0.0029802 82.162 0.998088 33.1976 0.525591 33.198 1 S EMKNDKSEEEQSS CK2 0.117 4.98005E-10 155.9 _NDKpSEEEQSSSSVK_ NDKS(1)EEEQSSSSVK NDKS(72.02)EEEQS(-72.02)S(-103.77)S(-116.8)S(-131.05)VK 4 2 817.33308 -0.26334 2598000 0.58037 285910 0 0 2222300 0 36977 52834 425 332 11 11 5389 6132 52388 32040 Mix4_TiO2_Reinj_1_3 1509 52388 32040 Mix4_TiO2_Reinj_1_3 1509 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.999987 48.9601 0 0 0.999987 48.9601 0.0410633 48.96 0 0 0 0 1 S KSKENKSPAIKYR Proline-directed 0.05 0.0410633 48.96 _SKENKpSPAIK_ SKENKS(1)PAIK S(-48.96)KENKS(48.96)PAIK 6 2 591.29993 0.30401 671570 0 0 0 671570 0 0 0 426 332 26 26 6785 7763 68791 42190 Mix4_TiO2_Reinj_1_4 5025 68791 42190 Mix4_TiO2_Reinj_1_4 5025 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.289039 0 0.0282856 -14.4128 4.20335E-05 97.053 0.289039 0 5.10705E-08 112.38 4.02116E-05 -43.8294 0.101148 59.961 0.000342122 -32.5644 0.190729 58.45 1 S NTPEPVSTSVSHY GSK3 0.081 5.10705E-08 112.38 _YRPENTPEPVpSTSVSHYGAEPTTVSPCPSSSAK_ Y(0.001)RPENT(0.17)PEPVS(0.289)T(0.289)S(0.22)VS(0.03)HY(0.001)GAEPTTVSPCPSSSAK Y(-23.79)RPENT(-2.31)PEPVS(0)T(0)S(-1.19)VS(-9.79)HY(-25.91)GAEPT(-77.55)T(-77.55)VS(-83.25)PCPS(-93.95)S(-98.59)S(-98.59)AK 11 3 1200.5381 -0.88168 0 0 0 0 0 0 0 0 0 427 332 40 40 6785 7763 68784 42180 Mix4_InSol_TiO2_1 5450 68791 42190 Mix4_TiO2_Reinj_1_4 5025 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.97115 20.1672 0.901849 14.731 4.20335E-05 97.053 0.886476 10.4865 5.10705E-08 112.38 0.97115 20.1672 0.101148 59.961 0.852758 10.8189 0.190729 58.45 1 S AEPTTVSPCPSSS GSK3;Proline-directed 0.05 5.10705E-08 112.38 _YRPENTPEPVSTSVSHYGAEPTTVpSPCPSSSAK_ YRPENTPEPVSTSVSHYGAEPT(0.009)T(0.009)VS(0.971)PCPS(0.007)S(0.002)S(0.001)AK Y(-50.26)RPENT(-46.9)PEPVS(-43.83)T(-43.83)S(-43.83)VS(-44.16)HY(-44.16)GAEPT(-20.17)T(-20.17)VS(20.17)PCPS(-21.55)S(-26.26)S(-30.66)AK 25 4 900.65536 -0.69198 4479200 5.6337 882740 0 0 2629500 0 271390 695570 428 333;334 228;207 228 99 115 1040 661 Mix4_TiO2_Reinj_1_4 4139 1040 661 Mix4_TiO2_Reinj_1_4 4139 P07948;P07948-2 P07948;P07948-2 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3;>sp|P07948-2|LYN_HUMAN Isoform LYN B of Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN 1 39.0984 1 19.914 0.453319 19.914 1 39.0984 0.121665 39.098 1 S LEKACISPKPQKP CDK1;Proline-directed 0.0057 0.121665 39.098 _ACIpSPKPQKPWDK_ ACIS(1)PKPQKPWDK ACIS(39.1)PKPQKPWDK 4 3 545.59686 0.75551 177190 22148 0 0 155040 0 0 0 429 333 38 38 1117;6035 1256;6884 10508 6462 Mix4_TiO2_Reinj_1_4 5010 59653 36197 Mix4_InSol_TiO2_1 4156 P07948 P07948 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3 0.87088 8.29178 0.87088 8.29178 0.206571 41.345 5.91369E-08 -72.28 0.00599192 72.28 2.98609E-06 -55.2403 0.0277295 55.24 1 S YVRDPTSNKQQRP 0.00599192 72.28 _DPTpSNKQQRPVPESQLLPGQR_ DPT(0.129)S(0.871)NKQQRPVPESQLLPGQR DPT(-8.29)S(8.29)NKQQRPVPES(-41.34)QLLPGQR 4 3 819.07449 -0.93563 403960 0 0 0 403960 0 0 0 430 333 11 11 1226;2288;2290;5390 1379;2586;2587;2590;6133 21093 12940 Mix4_TiO2_1_5 3965 11482 7021 Mix4_TiO2_1_4 4441 P07948 P07948 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3 0.99996 44.016 0.99996 44.016 3.02357E-08 173.83 0.994624 22.6719 0.0193321 62.173 0.999296 31.5215 0.000234742 137.59 0 0 0.99986 38.5271 4.19961E-08 136.34 0.999865 38.6832 1.11258E-11 158.55 1 S KSKGKDSLSDDGV AURORA;AURORA-1;CK2 0.020748 3.02357E-08 173.83 _GKDpSLSDDGVDLK_ GKDS(1)LSDDGVDLK GKDS(44.02)LS(-44.02)DDGVDLK 4 2 714.81634 0.31276 14836000 34.3 2923800 46849 0 8456900 0 965950 2442000 431 333 13 13 1226;2288;2290;5390 1379;2586;2587;2590;6133 11482 7021 Mix4_TiO2_1_4 4441 11482 7021 Mix4_TiO2_1_4 4441 P07948 P07948 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3 1 65.7606 1 65.7606 3.02357E-08 173.83 0.999955 43.4594 0.0193321 62.173 0.999999 62.3393 0.000234742 137.59 0 0 0.998594 28.5154 4.19961E-08 136.34 0.999528 33.2593 1.11258E-11 158.55 1 S KGKDSLSDDGVDL 3.02357E-08 173.83 _DSLpSDDGVDLK_ DSLS(1)DDGVDLK DS(-65.76)LS(65.76)DDGVDLK 4 2 622.25812 -0.1217 92023000 212.76 16947000 283730 0 60453000 0 9299500 5038800 432 333;334 6;6 6 5390 6133 52406 32053 Mix4_InSol_Tio2_Reinj_2 3443 52405 32051 Mix4_InSol_Tio2_Reinj_1 4806 P07948;P07948-2 P07948;P07948-2 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3;>sp|P07948-2|LYN_HUMAN Isoform LYN B of Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN 0.597234 4.72123 0.00118048 -29.1693 4.20987E-07 125.94 0.0610178 -11.626 6.11381E-07 120.71 0.0643586 -8.61473 4.19961E-08 136.34 0.597234 4.72123 1.11258E-11 158.55 1 S _MGCIKSKGKDSL 1.11258E-11 158.55 _pSKGKDSLSDDGVDLK_ S(0.597)KGKDS(0.201)LS(0.201)DDGVDLK S(4.72)KGKDS(-4.72)LS(-4.72)DDGVDLK 1 2 822.37983 0.13958 14589 0 0 0 0 0 0 14589 433 334 11 11 1226;2288;2289;5390 1379;2586;2587;2589;6133 21093 12940 Mix4_TiO2_1_5 3965 11482 7021 Mix4_TiO2_1_4 4441 P07948-2 P07948-2 P07948-2 >sp|P07948-2|LYN_HUMAN Isoform LYN B of Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN 0.99996 44.016 0.99996 44.016 3.02357E-08 173.83 0.994624 22.6719 0.0193321 62.173 0.999296 31.5215 0.000234742 137.59 0 0 0.99986 38.5271 4.19961E-08 136.34 0.999865 38.6832 1.11258E-11 158.55 1 S KSKGKDSLSDDGV AURORA;AURORA-1;CK2 0.020748 3.02357E-08 173.83 _GKDpSLSDDGVDLK_ GKDS(1)LSDDGVDLK GKDS(44.02)LS(-44.02)DDGVDLK 4 2 714.81634 0.31276 13753000 31.797 2923800 46849 0 8456900 0 965950 1359300 434 334 13 13 1226;2288;2289;5390 1379;2586;2587;2589;6133 11482 7021 Mix4_TiO2_1_4 4441 11482 7021 Mix4_TiO2_1_4 4441 P07948-2 P07948-2 P07948-2 >sp|P07948-2|LYN_HUMAN Isoform LYN B of Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN 1 65.7606 1 65.7606 3.02357E-08 173.83 0.999955 43.4594 0.0193321 62.173 0.999999 62.3393 0.000234742 137.59 0 0 0.998594 28.5154 4.19961E-08 136.34 0.999528 33.2593 1.11258E-11 158.55 1 S KGKDSLSDDGVDL 3.02357E-08 173.83 _DSLpSDDGVDLK_ DSLS(1)DDGVDLK DS(-65.76)LS(65.76)DDGVDLK 4 2 622.25812 -0.1217 90450000 209.12 16947000 283730 0 60453000 0 7771000 4994600 435 339 775 775 3205 3635 30427 18917 Mix4_InSol_Tio2_Reinj_1 2055 30426 18916 Mix4_InSol_TiO2_1 2009 P08237;P08237-2 P08237 P08237 >sp|P08237|K6PF_HUMAN 6-phosphofructokinase, muscle type OS=Homo sapiens GN=PFKM PE=1 SV=2;>sp|P08237-2|K6PF_HUMAN Isoform 2 of 6-phosphofructokinase, muscle type OS=Homo sapiens GN=PFKM 1 5.11219 1 46.9295 0.108352 46.929 1 5.11219 1.13787 5.1122 1 S HITRKRSGEAAV_ CAMK2;CHK1;CK1;PKA;PKD 0.004788 0.108352 46.929 _KRpSGEAAV_ KRS(1)GEAAV KRS(5.11)GEAAV 3 2 449.21312 -0.41735 35255 0 0 0 0 0 15956 19299 436 340 226 226 1609 1806 14818 8994 Mix4_TiO2_Reinj_1_3 2806 14817 8993 Mix4_TiO2_1_3 2238 P08238 P08238 P08238 >sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta OS=Homo sapiens GN=HSP90AB1 PE=1 SV=4 1 199.347 1 217.001 1.14006E-27 217 1 199.347 1.38866E-19 199.35 1 S EREKEISDDEAEE CK2 0.117 1.14006E-27 217 _EKEIpSDDEAEEEK_ EKEIS(1)DDEAEEEK EKEIS(199.35)DDEAEEEK 5 2 815.82201 -0.0075565 580640 154280 0 0 426360 0 0 0 437 340 255 255 2732;2733;2734 3113;3114;3116 25887 16042 Mix4_TiO2_Reinj_1_5 2692 25868 16006 Mix4_TiO2_1_3 2100 P08238;Q58FF8 P08238 P08238 >sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta OS=Homo sapiens GN=HSP90AB1 PE=1 SV=4;>sp|Q58FF8|H90B2_HUMAN Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens GN=HSP90AB2P PE=1 SV=2 1 75.7105 1 102.281 5.56639E-26 197.06 1 91.3646 0.000966939 91.365 1 75.7105 8.10779E-22 194.85 0 0 1 94.7148 1.8278E-12 147.31 1 76.7128 1.07321E-12 144.52 1 S KIEDVGSDEEDDS CK2 0.117 5.56639E-26 197.06 _IEDVGpSDEEDDSGKDKK_ IEDVGS(1)DEEDDSGKDKK IEDVGS(75.71)DEEDDS(-75.71)GKDKK 6 3 649.26852 -0.22033 118270000 420.62 24682000 50543 0 91817000 0 703230 1020300 438 340 261 261 2732;2733;2734 3113;3114;3116 25826 15973 Mix4_TiO2_Reinj_1_1 2552 25868 16006 Mix4_TiO2_1_3 2100 P08238;Q58FF8 P08238 P08238 >sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta OS=Homo sapiens GN=HSP90AB1 PE=1 SV=4;>sp|Q58FF8|H90B2_HUMAN Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens GN=HSP90AB2P PE=1 SV=2 0.965789 14.5072 0.409289 -1.59345 5.56639E-26 197.06 0.0597597 -11.9683 0.000966939 91.365 0.965789 14.5072 8.10779E-22 194.85 0 0 0.042635 -13.5131 1.8278E-12 147.31 0.000896035 -30.4729 1.07321E-12 144.52 1 S SDEEDDSGKDKKK CK2 0.117 5.56639E-26 197.06 _IEDVGSDEEDDpSGKDK_ IEDVGS(0.034)DEEDDS(0.966)GKDK IEDVGS(-14.51)DEEDDS(14.51)GKDK 12 3 606.5702 -0.434 246480 0.87657 0 0 0 246480 0 0 0 439 342 1008 1008 5850 6670;6671;6672 57707 35108 Mix4_TiO2_Reinj_1_4 4594 57693 35105 Mix4_InSol_Tio2_Reinj_1 5884 P08581-2;P08581 P08581-2 P08581-2 >sp|P08581-2|MET_HUMAN Isoform 2 of Hepatocyte growth factor receptor OS=Homo sapiens GN=MET;>sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sapiens GN=MET PE=1 SV=4 0.945677 12.5137 1.15509E-08 -79.3588 0.000306728 95.984 0 0 0.945677 12.5137 3.16731E-16 163.96 0.687707 3.43047 9.63488E-13 145.76 0.712534 3.94366 2.43636E-20 184.06 1 S VSARSVSPTTEMV CAMK2;PKA/AKT;Proline-directed 0.00111111 5.22604E-26 198.15 _SVpSPTTEM(ox)VSNESVDYR_ S(0.053)VS(0.946)PT(0.001)TEMVSNESVDYR S(-12.51)VS(12.51)PT(-28.69)T(-44.53)EMVS(-76.61)NES(-112.34)VDY(-163.96)R 3 2 998.91391 0.018562 1448700 0 0 0 220590 0 713360 514790 440 342 1015 1015 5850 6670;6671;6672 57692 35104 Mix4_InSol_Tio2_Reinj_1 5558 57693 35105 Mix4_InSol_Tio2_Reinj_1 5884 P08581-2;P08581 P08581-2 P08581-2 >sp|P08581-2|MET_HUMAN Isoform 2 of Hepatocyte growth factor receptor OS=Homo sapiens GN=MET;>sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sapiens GN=MET PE=1 SV=4 0.992111 22.2484 0.00346009 -24.5941 0.000306728 95.984 0 0 2.06515E-08 -76.6079 3.16731E-16 163.96 0.998721 29.4489 9.63488E-13 145.76 0.992111 22.2484 5.22604E-26 198.15 1 S PTTEMVSNESVDY CK1 0.143 5.22604E-26 198.15 _SVSPTTEMVpSNESVDYR_ SVSPT(0.001)T(0.006)EMVS(0.992)NES(0.001)VDYR S(-56.9)VS(-48.16)PT(-30.75)T(-22.25)EMVS(22.25)NES(-29.45)VDY(-101.91)R 10 2 990.91645 -0.17882 72203 0 0 0 0 0 0 72203 441 342 1018 1018 5850 6670;6671;6672 57706 35107 Mix4_TiO2_1_4 3881 57693 35105 Mix4_InSol_Tio2_Reinj_1 5884 P08581-2;P08581 P08581-2 P08581-2 >sp|P08581-2|MET_HUMAN Isoform 2 of Hepatocyte growth factor receptor OS=Homo sapiens GN=MET;>sp|P08581|MET_HUMAN Hepatocyte growth factor receptor OS=Homo sapiens GN=MET PE=1 SV=4 0.996539 24.5941 0.996539 24.5941 0.000306728 95.984 0 0 5.52125E-12 -112.337 3.16731E-16 163.96 0.0188113 -15.4209 5.81783E-26 196.27 0.00112572 -29.4513 5.22604E-26 198.15 1 S EMVSNESVDYRAT CK1 0.081 5.22604E-26 198.15 _SVSPTTEM(ox)VSNEpSVDYR_ SVSPTTEMVS(0.003)NES(0.997)VDYR S(-79.9)VS(-79.36)PT(-70.13)T(-59.92)EMVS(-24.59)NES(24.59)VDY(-84.8)R 13 2 998.91391 0.37792 19325 19325 0 0 0 0 0 0 442 343 226 226 6710 7683 68051 41759 Mix4_TiO2_Reinj_1_3 3709 68051 41759 Mix4_TiO2_Reinj_1_3 3709 P08621;P08621-4 P08621 P08621 >sp|P08621|RU17_HUMAN U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens GN=SNRNP70 PE=1 SV=2;>sp|P08621-4|RU17_HUMAN Isoform 4 of U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens GN=SNRNP70 1 71.2469 0 0 0 0 1 71.2469 0.0116938 71.247 0 0 0 0 1 S DERPGPSPLPHRD Proline-directed 0.05 0.0116938 71.247 _YDERPGPpSPLPHR_ YDERPGPS(1)PLPHR Y(-71.25)DERPGPS(71.25)PLPHR 8 3 534.24711 0.15034 659630 0 0 0 659630 0 0 0 443 344 459 459 886 1000 8477 5150 Mix4_TiO2_Reinj_1_4 4000 8477 5150 Mix4_TiO2_Reinj_1_4 4000 P08670 P08670 P08670 >sp|P08670|VIME_HUMAN Vimentin OS=Homo sapiens GN=VIM PE=1 SV=4 0.980281 16.9647 0.86242 7.97164 0.00135335 88.34 0.980281 16.9647 3.78724E-06 112.83 1 S QVINETSQHHDDL 3.78724E-06 112.83 _DGQVINETpSQHHDDLE_ DGQVINET(0.02)S(0.98)QHHDDLE DGQVINET(-16.96)S(16.96)QHHDDLE 9 2 958.88654 1.5138 307870 0.030763 112870 0 0 195000 0 0 0 444 344 56 56 5486 6243 53554 32751 Mix4_InSol_Tio2_Reinj_1 5443 53558 32756 Mix4_TiO2_Reinj_1_4 5146 P08670 P08670 P08670 >sp|P08670|VIME_HUMAN Vimentin OS=Homo sapiens GN=VIM PE=1 SV=4 0.994598 23.899 0.898347 10.4258 1.59289E-06 120.73 0.977348 19.0414 0.00147538 91.248 0.945145 13.6594 4.58367E-07 132.67 0.990505 20.2321 4.7477E-07 132.5 0.994598 23.899 1.77969E-06 118.77 1 S RSLYASSPGGVYA Polo box;Proline-directed 0.00405 4.58367E-07 132.67 _SLYASpSPGGVYATR_ SLYAS(0.001)S(0.995)PGGVY(0.004)ATR S(-77.68)LY(-97.18)AS(-28.68)S(23.9)PGGVY(-23.9)AT(-67.27)R 6 2 754.84269 0.79701 3214300 365010 43039 0 1521600 0 676950 607750 445 347 206 206 36 46 431 255 Mix4_TiO2_Reinj_1_2 6155 431 255 Mix4_TiO2_Reinj_1_2 6155 P09496;P09496-3;P09496-2 P09496 P09496 >sp|P09496|CLCA_HUMAN Clathrin light chain A OS=Homo sapiens GN=CLTA PE=1 SV=1;>sp|P09496-3|CLCA_HUMAN Isoform 3 of Clathrin light chain A OS=Homo sapiens GN=CLTA;>sp|P09496-2|CLCA_HUMAN Isoform Non-brain of Clathrin light chain A OS=Homo sapiens GN=CLTA 0.997525 26.1578 0.987009 21.1473 6.86625E-24 167.15 0.997525 26.1578 2.9132E-32 181.2 0 0 0 0 1 S NDIDESSPGTEWE Polo box;Proline-directed 0.00405 2.9132E-32 181.2 _AAEEAFVNDIDESpSPGTEWER_ AAEEAFVNDIDES(0.002)S(0.998)PGTEWER AAEEAFVNDIDES(-26.16)S(26.16)PGT(-42.33)EWER 14 2 1216.4999 0.06351 138870 0.24467 47785 0 0 91081 0 0 0 446 351 4 4 5245;5246;5401 5970;5972;6147 50947 31235 Mix4_TiO2_Reinj_1_2 2528 50928 31228 Mix4_TiO2_Reinj_1_2 2937 P09651;P09651-2;P09651-3;P0C7M2 P09651 P09651 >sp|P09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens GN=HNRNPA1 PE=1 SV=5;>sp|P09651-2|ROA1_HUMAN Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens GN=HNRNPA1;>sp|P09651-3|ROA1_HUMAN Isoform 2 of Heterog 0.781044 5.52319 0.340789 -2.8654 0.00466936 75.533 0 0 0 0 0.781044 5.52319 0.00163706 95.244 0.56345 1.54904 0.0115877 71.373 0.126876 -8.37697 0.0159642 66.173 1 S ___MSKSESPKEP 0.00163706 95.244 _pSESPKEPEQLRK_ S(0.781)ES(0.219)PKEPEQLRK S(5.52)ES(-5.52)PKEPEQLRK 1 2 754.36125 0.0044434 518040 22.273 0 0 0 383190 0 134850 0 447 351 6 6 5245;5246;5401 5970;5972;6147 50928 31228 Mix4_TiO2_Reinj_1_2 2937 50928 31228 Mix4_TiO2_Reinj_1_2 2937 P09651;P09651-2;P09651-3;P0C7M2 P09651 P09651 >sp|P09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens GN=HNRNPA1 PE=1 SV=5;>sp|P09651-2|ROA1_HUMAN Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens GN=HNRNPA1;>sp|P09651-3|ROA1_HUMAN Isoform 2 of Heterog 0.99968 34.948 0.998325 27.7536 0.00466936 75.533 0 0 0 0 0.99968 34.948 0.00163706 95.244 0.987975 19.1465 0.0115877 71.373 0.956532 15.4625 0.0159642 66.173 1 S _MSKSESPKEPEQ CDK1;CHK1;CK1;CK2;Proline-directed 0.0057 0.00163706 95.244 _SEpSPKEPEQLR_ SES(1)PKEPEQLR S(-34.95)ES(34.95)PKEPEQLR 3 3 460.54493 -0.23749 3272100 140.69 378630 0 0 2437900 0 167260 288340 448 355 180 180 6128 6995 60525 36590 Mix4_TiO2_Reinj_1_4 3658 60525 36590 Mix4_TiO2_Reinj_1_4 3658 P0C1Z6 P0C1Z6 P0C1Z6 >sp|P0C1Z6|TFPT_HUMAN TCF3 fusion partner OS=Homo sapiens GN=TFPT PE=1 SV=1 1 78.0085 0 0 0 0 1 78.0085 4.08223E-06 99.941 1 S APPEPGSPAPGEG ERK/MAPK;Proline-directed 0.0025 4.08223E-06 99.941 _TPAPPEPGpSPAPGEGPSGR_ TPAPPEPGS(1)PAPGEGPSGR T(-99.94)PAPPEPGS(78.01)PAPGEGPS(-78.01)GR 9 2 919.40945 -1.1875 162050 0 0 0 162050 0 0 0 449 358 86 86 5563 6338 54461 33340 Mix4_TiO2_Reinj_1_4 3755 54460 33339 Mix4_TiO2_1_4 3160 P10075 P10075 P10075 >sp|P10075|GLI4_HUMAN Zinc finger protein GLI4 OS=Homo sapiens GN=GLI4 PE=1 SV=2 0.999993 51.5661 0.999989 49.6876 3.83943E-09 132.28 0.999993 51.5661 5.84496E-09 129.62 1 S PEQAPRSPGSQAP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.83943E-09 132.28 _pSPGSQAPDEGAGGALR_ S(1)PGSQAPDEGAGGALR S(51.57)PGS(-51.57)QAPDEGAGGALR 1 2 775.33576 1.5266 108880 29168 0 0 79716 0 0 0 450 359 186 186 4560 5179 43209 26501 Mix4_TiO2_Reinj_1_3 6250 43209 26501 Mix4_TiO2_Reinj_1_3 6250 P10398 P10398 P10398 >sp|P10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf OS=Homo sapiens GN=ARAF PE=1 SV=2 0.989247 19.6395 0 0 0.989247 19.6395 0.0709096 55.548 1 S LTPQGPSPRTQHC CDK1;Proline-directed 0.0057 0.0709096 55.548 _QHEAPSNRPLNELLTPQGPpSPR_ QHEAPSNRPLNELLT(0.011)PQGPS(0.989)PR QHEAPS(-53.83)NRPLNELLT(-19.64)PQGPS(19.64)PR 20 3 840.07813 0.39434 518790 0 0 0 518790 0 0 0 451 360 187 187 2968 3376 28289 17572 Mix4_InSol_Tio2_Reinj_1 972 28288 17571 Mix4_InSol_TiO2_1 890 P10412 P10412 P10412 >sp|P10412|H14_HUMAN Histone H1.4 OS=Homo sapiens GN=HIST1H1E PE=1 SV=2 1 38.8775 0 0 1 41.7542 0.142003 41.754 1 38.8775 0.183408 38.878 1 S PKKAPKSPAKAKA CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.142003 41.754 _KAPKpSPAK_ KAPKS(1)PAK KAPKS(38.88)PAK 5 2 453.74406 -0.28001 153050 0 0 0 0 0 53160 99888 452 361 77 77 5948 6783 58616 35537 Mix4_InSol_TiO2_1 5064 58618 35540 Mix4_TiO2_1_4 4068 P10644 P10644 P10644 >sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens GN=PRKAR1A PE=1 SV=1 0.489127 0.692409 2.68765E-08 -75.7063 0.000590397 91.686 0.0202484 -16.8322 0.713926 24.591 7.52498E-06 -51.2349 0.000749808 89.742 0.489127 0.692409 0.737785 23.881 0.000185848 -37.3068 0.286542 37.307 1 S AGTRTDSREDEIS CAMK2;CK1;CK2 0.042 0.000590397 91.686 _TDpSREDEISPPPPNPVVK_ T(0.094)DS(0.489)REDEIS(0.417)PPPPNPVVK T(-7.17)DS(0.69)REDEIS(-0.69)PPPPNPVVK 3 3 686.32441 0.069879 0 0 0 0 0 0 0 0 453 361 83 83 5948 6783 58618 35540 Mix4_TiO2_1_4 4068 58618 35540 Mix4_TiO2_1_4 4068 P10644 P10644 P10644 >sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens GN=PRKAR1A PE=1 SV=1 1 75.7063 1 75.7063 0.000590397 91.686 0.976359 16.8322 0.713926 24.591 0.999991 51.2349 0.000749808 89.742 0.417043 -0.692409 0.737785 23.881 0.999628 37.3068 0.286542 37.307 1 S SREDEISPPPPNP Proline-directed 0.05 0.000590397 91.686 _TDSREDEIpSPPPPNPVVK_ TDSREDEIS(1)PPPPNPVVK T(-82.39)DS(-75.71)REDEIS(75.71)PPPPNPVVK 9 2 1028.983 0.44998 584900 123920 58179 0 333690 0 0 69107 454 367 2409 2409 358 409 3353 2012 Mix4_TiO2_1_1 5758 3356 2015 Mix4_TiO2_Reinj_1_1 6410 P11717 P11717 P11717 >sp|P11717|MPRI_HUMAN Cation-independent mannose-6-phosphate receptor OS=Homo sapiens GN=IGF2R PE=1 SV=2 0.999995 56.246 0.999995 56.246 2.81441E-07 112.58 0 0 0.999701 38.2533 8.91781E-12 132.67 0 0 0 0 1 S HGDDQDSEDEVLT CK2 0.117 8.91781E-12 132.67 _ALSSLHGDDQDpSEDEVLTIPEVK_ ALSSLHGDDQDS(1)EDEVLTIPEVK ALS(-56.25)S(-56.25)LHGDDQDS(56.25)EDEVLT(-70.68)IPEVK 12 2 1289.0838 0.46053 1213400 319130 0 0 894280 0 0 0 455 367 2479 2479 3796 4289 36069 22318 Mix4_TiO2_Reinj_1_5 7843 36067 22316 Mix4_TiO2_Reinj_1_1 7380 P11717 P11717 P11717 >sp|P11717|MPRI_HUMAN Cation-independent mannose-6-phosphate receptor OS=Homo sapiens GN=IGF2R PE=1 SV=2 0.679381 3.26124 0.215011 -5.62404 1.08074E-07 134.55 0 0 0.679381 3.26124 1.15931E-11 157.84 0 0 1 S SSTKLVSFHDDSD CK1;CK2 0.117 1.15931E-11 157.84 _LVpSFHDDSDEDLLHI_ LVS(0.679)FHDDS(0.321)DEDLLHI LVS(3.26)FHDDS(-3.26)DEDLLHI 3 3 612.26802 -0.28018 55846 0 0 0 55846 0 0 0 456 367 2484 2484 3796 4289 36067 22316 Mix4_TiO2_Reinj_1_1 7380 36067 22316 Mix4_TiO2_Reinj_1_1 7380 P11717 P11717 P11717 >sp|P11717|MPRI_HUMAN Cation-independent mannose-6-phosphate receptor OS=Homo sapiens GN=IGF2R PE=1 SV=2 1 92.2121 1 63.1578 1.08074E-07 134.55 0 0 1 92.2121 1.15931E-11 157.84 0 0 1 S VSFHDDSDEDLLH CK2 0.117 1.15931E-11 157.84 _LVSFHDDpSDEDLLHI_ LVSFHDDS(1)DEDLLHI LVS(-92.21)FHDDS(92.21)DEDLLHI 8 2 917.89839 0.7636 857850 131070 0 0 726780 0 0 0 457 372 1437 1437 5495 6257 53690 32815 Mix4_TiO2_1_5 2401 53690 32815 Mix4_TiO2_1_5 2401 P13533;P12883 P13533 P13533 >sp|P13533|MYH6_HUMAN Myosin-6 OS=Homo sapiens GN=MYH6 PE=1 SV=4;>sp|P12883|MYH7_HUMAN Myosin-7 OS=Homo sapiens GN=MYH7 PE=1 SV=5 1 38.4419 1 38.4419 0.132197 38.442 1 S MVDVERSNAAAAA 0.132197 38.442 _pSNAAAAALDKKQR_ S(1)NAAAAALDKKQR S(38.44)NAAAAALDKKQR 1 2 712.3563 -1.05 127320 127320 0 0 0 0 0 0 458 373 69 69 3417 3859 32099 19845 Mix4_InSol_Tio2_Reinj_1 6826 32102 19850 Mix4_TiO2_1_3 5593 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 0.900087 9.86355 0.000876243 -27.9807 1.12018E-25 198.67 0 0 4.67766E-10 -93.298 5.63255E-13 153.78 3.03923E-05 -45.0298 8.76977E-16 160.95 0.900087 9.86355 3.31494E-16 170.3 1 S LFGGFNSSDTVTS 1.12018E-25 198.67 _LFGGFNpSSDTVTSPQR_ LFGGFNS(0.9)S(0.093)DT(0.004)VT(0.002)SPQR LFGGFNS(9.86)S(-9.86)DT(-23.02)VT(-25.62)S(-40.89)PQR 7 2 896.89872 1.0568 64108 0.53645 0 0 0 0 0 0 64108 459 373 75 75 3417 3859 32102 19850 Mix4_TiO2_1_3 5593 32102 19850 Mix4_TiO2_1_3 5593 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 0.999896 39.8259 0.999896 39.8259 1.12018E-25 198.67 0 0 0.999615 34.3845 5.63255E-13 153.78 0.999853 38.3211 8.76977E-16 160.95 0.999854 38.3746 3.31494E-16 170.3 1 S SSDTVTSPQRAGP CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 1.12018E-25 198.67 _LFGGFNSSDTVTpSPQR_ LFGGFNSSDTVTS(1)PQR LFGGFNS(-122.63)S(-107.82)DT(-84.5)VT(-39.83)S(39.83)PQR 13 2 896.89872 0.10432 7165600 59.961 2628600 0 0 1652200 0 1576100 1308800 460 373 17 17 5031;5040;5425;5426 5722;5732;6174;6175 52869 32310 Mix4_TiO2_Reinj_1_4 4955 48575 29697 Mix4_TiO2_Reinj_1_4 4308 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 1 83.4104 1 99.8227 6.16546E-08 110.25 0.999904 44.9504 0.723105 48.431 1 83.4104 2.17586E-12 134.14 0 0 0.0811123 -8.38046 1.49696 31.987 0.991051 22.97 1.31268 36.538 1 S ASQRRRSLEPAEN AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.004788 2.17586E-12 134.14 _pSLEPAENVHGAGGGAFPASQTPSK_ S(1)LEPAENVHGAGGGAFPASQTPSK S(83.41)LEPAENVHGAGGGAFPAS(-83.41)QT(-83.41)PS(-83.41)K 1 3 797.03218 0.26313 103690000 6304.3 6122500 200540 0 97128000 0 0 243250 461 373 35 35 5031;5040;5425;5426 5722;5732;6174;6175 48576 29699 Mix4_TiO2_Reinj_1_4 4319 48575 29697 Mix4_TiO2_Reinj_1_4 4308 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 0.852181 9.65477 0.431217 -0.771599 6.16546E-08 110.25 0.182361 -3.95085 0.723105 48.431 0.852181 9.65477 2.17586E-12 134.14 0 0 0.176189 -5.01154 1.49696 31.987 0.00187562 -27.2295 1.31268 36.538 1 S GGAFPASQTPSKP GSK3 0.081 2.17586E-12 134.14 _RRSLEPAENVHGAGGGAFPApSQTPSK_ RRS(0.023)LEPAENVHGAGGGAFPAS(0.852)QT(0.092)PS(0.032)K RRS(-15.64)LEPAENVHGAGGGAFPAS(9.65)QT(-9.65)PS(-14.21)K 21 2 1351.1457 0.64769 91277 5.5494 0 0 0 91277 0 0 0 462 373 39 39 5031;5040;5425;5426 5722;5732;6174;6175 52879 32312 Mix4_InSol_TiO2_1 5096 48575 29697 Mix4_TiO2_Reinj_1_4 4308 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 0.558641 5.01154 0.0393941 -13.3732 6.16546E-08 110.25 0.182361 -3.95085 0.723105 48.431 0.0322954 -14.2139 2.17586E-12 134.14 0 0 0.558641 5.01154 1.49696 31.987 0.00178462 -27.4455 1.31268 36.538 1 S PASQTPSKPASAD CK1;GSK3 0.081 2.17586E-12 134.14 _SLEPAENVHGAGGGAFPASQTPpSKPASADGHR_ S(0.081)LEPAENVHGAGGGAFPAS(0.176)QT(0.176)PS(0.559)KPAS(0.008)ADGHR S(-8.38)LEPAENVHGAGGGAFPAS(-5.01)QT(-5.01)PS(5.01)KPAS(-18.51)ADGHR 23 3 1060.8213 -1.8501 182850 11.117 0 0 0 0 0 182850 0 463 373 104 104 5975 6815 58994 35794 Mix4_TiO2_Reinj_1_4 4899 58994 35794 Mix4_TiO2_Reinj_1_4 4899 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 0.999944 45.5315 0.998624 31.617 0.310089 31.617 0 0 0.999944 45.5315 0.117444 45.531 1 S RTETDLSFKKGER PLK1 0.033462 0.117444 45.531 _TETDLpSFK_ TETDLS(1)FK T(-45.53)ET(-45.53)DLS(45.53)FK 6 2 510.71791 -0.44151 198360 41165 0 0 157200 0 0 0 464 377 427 427 Phosphoserine 3869 4389 36738 22637 Mix4_TiO2_1_1 4377 36742 22641 Mix4_TiO2_Reinj_1_4 5536 P13646;CON__P13646-1 P13646 P13646 Cytokeratin-13;Keratin, type I cytoskeletal 13;Keratin-13 KRT13 >sp|P13646|K1C13_HUMAN Keratin, type I cytoskeletal 13 OS=Homo sapiens GN=KRT13 PE=1 SV=4;>P13646-1 SWISS-PROT:P13646-1 Tax_Id=9606 Gene_Symbol=KRT13 Isoform 1 of Keratin, type I cytoskeletal 13 P13646-1;P13646 0.998613 28.5815 0.998613 28.5815 0.00111661 93.415 0.997209 25.5357 0.000170816 103.45 0 0 0 0 1 S SSAGSVSPRSTSV CDK1;Proline-directed 0.0057 0.000170816 103.45 _M(ox)IGFPSSAGSVpSPR_ MIGFPSSAGS(0.001)VS(0.999)PR MIGFPS(-60.06)S(-57.25)AGS(-28.58)VS(28.58)PR 12 2 744.83127 0.23316 568660 166560 0 0 402100 0 0 0 + 465 379 652 652 2658 3023;3024 24795 15351 Mix4_TiO2_Reinj_1_3 1859 24795 15351 Mix4_TiO2_Reinj_1_3 1859 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.889145 9.04218 0.889145 9.04218 0.00037982 97.888 2 S PSLSRHSSPHQSE CK1;PKA 0.042 0.00037982 97.888 _HpSSPHQpSEDEEDPR_ HS(0.889)S(0.111)PHQS(1)EDEEDPR HS(9.04)S(-9.04)PHQS(58.67)EDEEDPR 2 2 905.30928 -0.0017325 312510 0 0 0 312510 0 0 0 466 379 653 653 2658 3023;3024 24796 15352 Mix4_TiO2_Reinj_1_5 2016 24795 15351 Mix4_TiO2_Reinj_1_3 1859 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.500813 0 0.500813 0 0.00037982 97.888 2 S SLSRHSSPHQSED CAMK2;CHK1;CHK1/2;CK1;GSK3;PKD;Polo box;Proline-directed 0.003192 0.00037982 97.888 _HpSSPHQpSEDEEDPR_ HS(0.501)S(0.501)PHQS(0.998)EDEEDPR HS(0)S(0)PHQS(24.87)EDEEDPR 3 2 905.30928 0.051421 69493 0 0 0 69493 0 0 0 467 379 657 657 2658 3023;3024 24795 15351 Mix4_TiO2_Reinj_1_3 1859 24795 15351 Mix4_TiO2_Reinj_1_3 1859 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.999999 58.6674 0.999999 58.6674 0.00037982 97.888 2 S HSSPHQSEDEEDP CK1;CK2 0.117 0.00037982 97.888 _HpSSPHQpSEDEEDPR_ HS(0.889)S(0.111)PHQS(1)EDEEDPR HS(9.04)S(-9.04)PHQS(58.67)EDEEDPR 7 2 905.30928 -0.0017325 312510 0 0 0 312510 0 0 0 468 379 710 710 4329;4969 4923;5650 47966 29326 Mix4_TiO2_Reinj_1_3 5857 41127 25299 Mix4_TiO2_Reinj_1_3 5912 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.963034 15.4489 0.777266 6.03334 8.38461E-13 130.41 0.963034 15.4489 4.34699E-26 159.07 8.84978E-07 -59.7867 0.0594364 59.787 0 0 1 S SGSKRNSVDTATS AURORA;AURORA-1;AURORA-A;CK1;PKA 0.006142092 4.34699E-26 159.07 _RNpSVDTATSSSLSTPSEPLSPTSSLGEERN_ RNS(0.963)VDT(0.027)AT(0.006)S(0.001)S(0.001)S(0.001)LSTPSEPLSPTSSLGEERN RNS(15.45)VDT(-15.45)AT(-22.25)S(-28.85)S(-28.85)S(-28.85)LS(-57)T(-56.65)PS(-85.75)EPLS(-102.25)PT(-102.25)S(-102.25)S(-102.25)LGEERN 3 3 1062.8193 1.1404 737700 0.42743 216690 0 0 521010 0 0 0 469 379 727 727 4329;4969 4923;5650 41127 25299 Mix4_TiO2_Reinj_1_3 5912 41127 25299 Mix4_TiO2_Reinj_1_3 5912 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.964314 15.1565 2.75369E-13 -124.507 8.38461E-13 130.41 0.964314 15.1565 4.34699E-26 159.07 0.842555 9.16496 0.0594364 59.787 0 0 1 S TPSEPLSPTSSLG CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 4.34699E-26 159.07 _NSVDTATSSSLSTPSEPLpSPTSSLGEERN_ NSVDTATSSSLSTPSEPLS(0.964)PT(0.029)S(0.005)S(0.001)LGEERN NS(-139.14)VDT(-125.1)AT(-130.28)S(-125.1)S(-118.85)S(-112.21)LS(-103.91)T(-98.99)PS(-74.54)EPLS(15.16)PT(-15.16)S(-22.6)S(-29.95)LGEERN 19 3 1010.7856 0.15455 851770 0.49353 0 0 0 649030 0 202740 0 470 379 641 641 4409;6769 5016;5017;7745;7746 41974 25875 Mix4_TiO2_1_3 3095 68650 42123 Mix4_TiO2_1_3 3980 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.994751 26.3733 0.994751 26.3733 0.00284783 80.156 1.34846E-07 -63.9304 0.0151495 63.93 0.943634 16.4432 0.443617 16.443 2 S RYPRPASVPPSPS CAMK2;GSK3 0.002856 0.00284783 80.156 _PApSVPPpSPSLSR_ PAS(0.995)VPPS(0.763)PS(0.148)LS(0.095)R PAS(26.37)VPPS(7.2)PS(-7.2)LS(-9.21)R 3 2 677.79383 0.14162 496290 269810 0 0 226480 0 0 0 471 379 645 645 4409;6769 5016;5017;7745;7746 68658 42128 Mix4_TiO2_Reinj_1_3 4613 41979 25877 Mix4_TiO2_1_3 3190 P13807 P13807 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle OS=Homo sapiens GN=GYS1 PE=1 SV=2 0.906762 12.3914 0.888119 9.12597 0.00408095 88.269 0.333333 0 0.0151495 63.93 0.906762 12.3914 0.0151495 63.931 1 S PASVPPSPSLSRH CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.00408095 88.269 _YPRPASVPPpSPSLSR_ YPRPASVPPS(0.907)PS(0.052)LS(0.041)R Y(-39.19)PRPAS(-39.19)VPPS(12.39)PS(-12.39)LS(-13.48)R 10 3 564.28193 -0.31632 169730 69227 0 0 100500 0 0 0 472 380 99 99 5072 5767 49053 29967 Mix4_TiO2_1_4 4286 49054 29968 Mix4_TiO2_Reinj_1_4 4745 P13861 P13861 P13861 >sp|P13861|KAP2_HUMAN cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens GN=PRKAR2A PE=1 SV=2 0.99959 34.6171 0.99959 34.6171 0.0162032 61.172 0.938066 11.9535 7.85382E-11 118.13 1 S RFNRRVSVCAETY AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.002856 7.85382E-11 118.13 _RVpSVCAETYNPDEEEEDTDPR_ RVS(1)VCAETYNPDEEEEDTDPR RVS(34.62)VCAET(-34.62)Y(-41.91)NPDEEEEDT(-61.17)DPR 3 2 1296.0156 0.16167 1516500 144300 0 0 1372200 0 0 0 473 380 78 78 6323 7227 63385 38639 Mix4_TiO2_Reinj_1_4 5586 63385 38639 Mix4_TiO2_Reinj_1_4 5586 P13861 P13861 P13861 >sp|P13861|KAP2_HUMAN cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens GN=PRKAR2A PE=1 SV=2 1 113.768 1 111.385 3.42141E-07 111.39 1 113.768 2.2091E-07 113.77 2 S ADAKGDSESEEDE CK2 0.117 2.2091E-07 113.77 _VADAKGDpSEpSEEDEDLEVPVPSR_ VADAKGDS(1)ES(1)EEDEDLEVPVPSR VADAKGDS(113.77)ES(113.77)EEDEDLEVPVPS(-113.77)R 8 3 878.35616 0.089158 4445100 942170 0 0 3502900 0 0 0 474 380 80 80 6323 7227 63385 38639 Mix4_TiO2_Reinj_1_4 5586 63385 38639 Mix4_TiO2_Reinj_1_4 5586 P13861 P13861 P13861 >sp|P13861|KAP2_HUMAN cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens GN=PRKAR2A PE=1 SV=2 1 113.768 1 111.385 3.42141E-07 111.39 1 113.768 2.2091E-07 113.77 2 S AKGDSESEEDEDL CK2 0.117 2.2091E-07 113.77 _VADAKGDpSEpSEEDEDLEVPVPSR_ VADAKGDS(1)ES(1)EEDEDLEVPVPSR VADAKGDS(113.77)ES(113.77)EEDEDLEVPVPS(-113.77)R 10 3 878.35616 0.089158 4445100 942170 0 0 3502900 0 0 0 475 386 750 750 227 261 2261 1456 Mix4_TiO2_Reinj_1_3 7349 2261 1456 Mix4_TiO2_Reinj_1_3 7349 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 1 122.132 0 0 1 122.132 3.53076E-20 179.04 1 S SLYACASPKTPIQ CDK1;Proline-directed 0.0057 3.53076E-20 179.04 _AGFQTEDFSLYACApSPK_ AGFQTEDFSLYACAS(1)PK AGFQT(-179.04)EDFS(-179.04)LY(-122.13)ACAS(122.13)PK 15 3 657.94466 0.038018 167720 0 0 0 167720 0 0 0 476 386 419 419 346 394 3222 1955 Mix4_TiO2_Reinj_1_4 1877 3211 1940 Mix4_InSol_TiO2_1 2107 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 1 8.53311 1 4.66962 0.274359 23.624 0 0 1 8.53311 0.208027 29.121 1 40.3962 0.0418561 48.698 1 25.961 0.059526 42.847 1 S VKALQKSPGPQRE NEK6;Proline-directed 0.05 0.0418561 48.698 _ALQKpSPGPQR_ ALQKS(1)PGPQR ALQKS(8.53)PGPQR 5 2 581.29244 0.4696 10384000 383070 0 0 3534000 0 3137200 3330200 477 386 399 399 1131;2134 1273;2418 19636 11993 Mix4_TiO2_Reinj_1_5 6597 19629 11976 Mix4_TiO2_1_3 5836 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.552881 1.04776 0.0494424 -12.6889 6.15238E-26 170.81 0 0 0.552881 1.04776 8.47887E-18 143.57 0.000634444 -31.9707 0.000163687 88.695 0.032958 -14.6565 0.386027 53.076 1 S GSTTGLSATPPAS CK1 0.143 6.15238E-26 170.81 _GDGGSTTGLpSATPPASLPGSLTNVK_ GDGGSTTGLS(0.553)AT(0.434)PPAS(0.012)LPGSLTNVK GDGGS(-32)T(-32)T(-38.7)GLS(1.05)AT(-1.05)PPAS(-16.65)LPGS(-42.09)LT(-71.28)NVK 10 2 1183.0678 0.46131 429850 0 0 0 429850 0 0 0 478 386 405 405 1131;2134 1273;2418 19630 11980 Mix4_TiO2_1_3 5909 19629 11976 Mix4_TiO2_1_3 5836 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.497555 0 0.497555 0 6.15238E-26 170.81 0 0 0.0119458 -16.6542 8.47887E-18 143.57 0.00055445 -32.556 0.000163687 88.695 0.000989471 -29.8821 0.386027 53.076 1 S SATPPASLPGSLT CK1;GSK3 0.081 6.15238E-26 170.81 _GDGGSTTGLSApTPPASLPGSLTNVK_ GDGGSTTGLS(0.003)AT(0.498)PPAS(0.498)LPGS(0.002)LTNVK GDGGS(-66.05)T(-66.05)T(-73.62)GLS(-22.55)AT(0)PPAS(0)LPGS(-23.69)LT(-76.21)NVK 16 2 1183.0678 0.18734 0 0 0 0 0 0 0 0 479 386 363 363 1177;5734 1322;6535 11048 6776 Mix4_InSol_TiO2_1 8534 11052 6781 Mix4_TiO2_Reinj_1_3 8189 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.608402 4.92546 0.452167 0 1.40186E-17 139.48 0 0 0.393829 -1.13976 6.2958E-45 202.91 0 0 0.608402 4.92546 0.136069 53.111 0.452399 0 0.0823986 56.42 1 S FGQRDRSSSAPNV CAMK2 0.042 6.2958E-45 202.91 _DRpSSSAPNVHINTIEPVNIDDLIR_ DRS(0.608)S(0.196)S(0.196)APNVHINTIEPVNIDDLIR DRS(4.93)S(-4.93)S(-4.93)APNVHINT(-36.1)IEPVNIDDLIR 3 3 919.11854 -0.32768 166260 0 0 0 0 0 166260 0 480 386 364 364 1177;5734 1322;6535 56361 34434 Mix4_TiO2_Reinj_1_1 7828 11052 6781 Mix4_TiO2_Reinj_1_3 8189 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.512016 1.13976 0.452167 0 1.40186E-17 139.48 0 0 0.512016 1.13976 6.2958E-45 202.91 0 0 0.329098 0 0.136069 53.111 0.452399 0 0.0823986 56.42 1 S GQRDRSSSAPNVH PKA 0.042 6.2958E-45 202.91 _SpSSAPNVHINTIEPVNIDDLIR_ S(0.394)S(0.512)S(0.085)APNVHINT(0.009)IEPVNIDDLIR S(-1.14)S(1.14)S(-7.78)APNVHINT(-17.63)IEPVNIDDLIR 2 3 828.74252 0.10936 408030 0 0 0 408030 0 0 0 481 386 365 365 1177;5734 1322;6535 11052 6781 Mix4_TiO2_Reinj_1_3 8189 11052 6781 Mix4_TiO2_Reinj_1_3 8189 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.82669 6.87304 0.343555 0 1.40186E-17 139.48 0 0 0.82669 6.87304 6.2958E-45 202.91 0 0 0.329098 0 0.136069 53.111 0.214417 -2.21105 0.0823986 56.42 1 S QRDRSSSAPNVHI 14-3-3 binding;CAMK2;PKA/AKT 0.0001701 6.2958E-45 202.91 _DRSSpSAPNVHINTIEPVNIDDLIR_ DRS(0.003)S(0.17)S(0.827)APNVHINTIEPVNIDDLIR DRS(-23.77)S(-6.87)S(6.87)APNVHINT(-137.44)IEPVNIDDLIR 5 3 919.11854 0.61062 2712600 0 0 0 2712600 0 0 0 482 386 314 314 1983 2243 18046 10785 Mix4_TiO2_Reinj_1_3 7735 18051 10791 Mix4_TiO2_Reinj_1_5 7725 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.228762 0 0 0 0 0 0.228762 0 4.84745E-06 110.92 0 0 0 0 0 0 1 S AETALTSGSSPSA CK1 0.143 4.84745E-06 110.92 _FFEHHPIPQEEASLAETALpTSGSSPSAPASDSIGPQILTSPSPSK_ FFEHHPIPQEEAS(0.003)LAET(0.011)ALT(0.229)S(0.229)GS(0.229)S(0.229)PS(0.049)APAS(0.011)DS(0.011)IGPQILTSPSPSK FFEHHPIPQEEAS(-19.06)LAET(-13.03)ALT(0)S(0)GS(0)S(0)PS(-6.67)APAS(-13.28)DS(-13.28)IGPQILT(-43.07)S(-43.07)PS(-46.99)PS(-48.88)K 21 4 1171.5589 0.035414 0 0 0 0 0 0 0 0 483 386 316 316 1983 2243 18047 10786 Mix4_TiO2_Reinj_1_3 7766 18051 10791 Mix4_TiO2_Reinj_1_5 7725 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.362165 0 0 0 0 0 0.362165 0 4.84745E-06 110.92 0 0 0 0 0 0 1 S TALTSGSSPSAPA 4.84745E-06 110.92 _FFEHHPIPQEEASLAETALTSGpSSPSAPASDSIGPQILTSPSPSK_ FFEHHPIPQEEAS(0.002)LAET(0.002)ALT(0.015)S(0.041)GS(0.362)S(0.362)PS(0.128)APAS(0.044)DS(0.044)IGPQILT(0.001)SPSPSK FFEHHPIPQEEAS(-23.1)LAET(-23.56)ALT(-13.83)S(-9.47)GS(0)S(0)PS(-4.53)APAS(-9.17)DS(-9.17)IGPQILT(-27.59)S(-30.56)PS(-35.65)PS(-37.74)K 23 5 937.44858 0.087991 0 0 0 0 0 0 0 0 484 386 317 317 1983 2243 18047 10786 Mix4_TiO2_Reinj_1_3 7766 18051 10791 Mix4_TiO2_Reinj_1_5 7725 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.362165 0 0 0 0 0 0.362165 0 4.84745E-06 110.92 0 0 0 0 0 0 1 S ALTSGSSPSAPAS CK1;Polo box;Proline-directed 0.00405 4.84745E-06 110.92 _FFEHHPIPQEEASLAETALTSGpSSPSAPASDSIGPQILTSPSPSK_ FFEHHPIPQEEAS(0.002)LAET(0.002)ALT(0.015)S(0.041)GS(0.362)S(0.362)PS(0.128)APAS(0.044)DS(0.044)IGPQILT(0.001)SPSPSK FFEHHPIPQEEAS(-23.1)LAET(-23.56)ALT(-13.83)S(-9.47)GS(0)S(0)PS(-4.53)APAS(-9.17)DS(-9.17)IGPQILT(-27.59)S(-30.56)PS(-35.65)PS(-37.74)K 24 5 937.44858 0.087991 0 0 0 0 0 0 0 0 485 386 335 335 1983 2243 18048 10788 Mix4_TiO2_Reinj_1_3 7868 18051 10791 Mix4_TiO2_Reinj_1_5 7725 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.810596 7.24442 0 0 0 0 0.810596 7.24442 4.84745E-06 110.92 0 0 0 0 0 0 1 S QILTSPSPSKSIP CDK1;CDK2;GSK3;Proline-directed 0.0057 4.84745E-06 110.92 _FFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPpSPSK_ FFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILT(0.006)S(0.03)PS(0.811)PS(0.153)K FFEHHPIPQEEAS(-78.8)LAET(-69.97)ALT(-69.97)S(-69.97)GS(-69.97)S(-69.97)PS(-68.72)APAS(-62.65)DS(-58.93)IGPQILT(-21.1)S(-14.28)PS(7.24)PS(-7.24)K 42 4 1171.5589 0.0088992 5530400 0 0 0 5530400 0 0 0 486 386 337 337 1983 2243 18050 10790 Mix4_TiO2_Reinj_1_3 7857 18051 10791 Mix4_TiO2_Reinj_1_5 7725 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.479202 0 0 0 0 0 0.479202 0 4.84745E-06 110.92 0 0 0 0 0 0 1 S LTSPSPSKSIPIP CK1 0.143 4.84745E-06 110.92 _FFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPpSPSK_ FFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILT(0.009)S(0.033)PS(0.479)PS(0.479)K FFEHHPIPQEEAS(-64.51)LAET(-62.34)ALT(-59.4)S(-55.9)GS(-55.9)S(-55.9)PS(-55.9)APAS(-52.14)DS(-46.49)IGPQILT(-17.24)S(-11.68)PS(0)PS(0)K 44 3 1561.7428 -0.18908 0 0 0 0 0 0 0 0 487 386 446 446 4847 5510 46468 28479 Mix4_TiO2_1_3 6037 46468 28479 Mix4_TiO2_1_3 6037 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.989006 19.5406 0.989006 19.5406 1.84603E-31 198.37 0 0 0.971315 15.2971 2.63693E-21 166.02 0 0 0.980927 17.1123 3.31895E-27 194.42 0.5 0 0.00103562 81.186 1 S TLGRRDSSDDWEI CAMK2;CHK1;CHK1/2;CK2;PKA;PKD 0.003192 1.84603E-31 198.37 _RDpSSDDWEIPDGQITVGQR_ RDS(0.989)S(0.011)DDWEIPDGQITVGQR RDS(19.54)S(-19.54)DDWEIPDGQIT(-154.55)VGQR 3 2 1127.4922 0.1442 32171000 8411100 0 0 22056000 0 1143200 560710 488 386 447 447 4847 5510 46465 28474 Mix4_InSol_Tio2_Reinj_2 5235 46468 28479 Mix4_TiO2_1_3 6037 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.850681 7.5565 0.586586 1.51946 1.84603E-31 198.37 0 0 0.5 0 2.63693E-21 166.02 0 0 0.5 0 3.31895E-27 194.42 0.850681 7.5565 0.00103562 81.186 1 S LGRRDSSDDWEIP CAMK2 0.042 1.84603E-31 198.37 _RDSpSDDWEIPDGQITVGQR_ RDS(0.149)S(0.851)DDWEIPDGQITVGQR RDS(-7.56)S(7.56)DDWEIPDGQIT(-81.19)VGQR 4 2 1127.4922 -0.18086 22293000 6122600 0 0 14687000 0 801900 680880 489 386 727 727 5116 5820 49486 30232 Mix4_InSol_Tio2_Reinj_2 2145 49484 30225 Mix4_InSol_TiO2_1 3260 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.815153 9.45457 0.014786 -18.1711 0.054112 45.751 0 0 0.132532 -7.43929 0.00287775 73.975 0.00126902 -28.9598 0.00341934 107.95 0.815153 9.45457 0.00147123 88.897 1 S LPKIHRSASEPSL CK2 0.117 0.00341934 107.95 _pSASEPSLNR_ S(0.815)AS(0.092)EPS(0.092)LNR S(9.45)AS(-9.45)EPS(-9.45)LNR 1 2 520.72405 0.16915 36086 0 0 0 0 0 0 36086 490 386 729 729 5116 5820 49489 30239 Mix4_TiO2_Reinj_1_3 2976 49484 30225 Mix4_InSol_TiO2_1 3260 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.999171 31.3809 0.989003 19.9472 0.054112 45.751 0 0 0.999171 31.3809 0.00287775 73.975 0.99873 28.9598 0.00341934 107.95 0.907256 9.90468 0.00147123 88.897 1 S KIHRSASEPSLNR 14-3-3 binding;CAMK2;CHK1;PKD 0.0001701 0.00341934 107.95 _SApSEPSLNR_ S(0.001)AS(0.999)EPSLNR S(-31.38)AS(31.38)EPS(-39.91)LNR 3 2 520.72405 -0.67526 10363000 1934100 0 0 5099100 0 1842000 1488000 491 386 151 151 5514 6278 53808 32903 Mix4_InSol_TiO2_1 2946 53821 32932 Mix4_TiO2_Reinj_1_5 2632 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.999932 41.705 0.998061 27.1154 0.256134 27.115 0 0 0.999893 39.7148 0.0644513 46.856 0.999932 41.705 0.0740326 44.143 0.997637 26.2556 0.266749 26.256 1 S ARSNPKSPQKPIV CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0644513 46.856 _SNPKpSPQKPIVR_ SNPKS(1)PQKPIVR S(-41.7)NPKS(41.7)PQKPIVR 5 3 477.5887 -0.57227 13437000 221690 0 0 7736100 0 2324300 3155200 492 387 74 74 4430 5040 42137 25960 Mix4_TiO2_1_2 4145 42138 25961 Mix4_TiO2_Reinj_1_2 4892 P15407 P15407 P15407 >sp|P15407|FOSL1_HUMAN Fos-related antigen 1 OS=Homo sapiens GN=FOSL1 PE=1 SV=1 0.89269 10.0832 0.89269 10.0832 0.462821 19.565 0.856426 7.75625 0.0111168 71.932 1 S LTYPQYSPPQPRP Proline-directed 0.05 0.0111168 71.932 _PLTYPQYpSPPQPR_ PLT(0.01)Y(0.01)PQY(0.088)S(0.893)PPQPR PLT(-19.57)Y(-19.57)PQY(-10.08)S(10.08)PPQPR 8 2 812.38198 -1.1481 62201 15836 0 0 46365 0 0 0 493 388 264 264 1881;5601 2124;6383 54785 33543 Mix4_TiO2_Reinj_1_2 5751 17286 10390 Mix4_TiO2_Reinj_1_2 6430 P15880 P15880 P15880 >sp|P15880|RS2_HUMAN 40S ribosomal protein S2 OS=Homo sapiens GN=RPS2 PE=1 SV=2 0.999531 33.3123 0.481885 2.69547 0.75993 2.6955 0 0 0.999531 33.3123 0.0152357 67.504 0 0 0 0 1 S ETVFTKSPYQEFT Proline-directed 0.05 0.0152357 67.504 _pSPYQEFTDHLVK_ S(1)PYQEFTDHLVK S(33.31)PY(-33.31)QEFT(-56.3)DHLVK 1 2 772.34506 -0.17069 172410 10.215 0 0 0 172410 0 0 0 494 392 434 434 2648 3011 24684 15295 Mix4_TiO2_Reinj_1_4 4622 24683 15294 Mix4_TiO2_Reinj_1_3 4666 P16591 P16591 P16591 >sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens GN=FER PE=1 SV=2 1 83.859 0.999994 52.4807 0.0370341 52.481 1 83.859 0.00295828 120.56 0.999997 55.7201 0.0261114 55.72 0.981651 17.2835 0.394523 17.283 1 S IAGIIRSPKSALG CDK1;Proline-directed 0.0057 0.00295828 120.56 _HSIAGIIRpSPK_ HSIAGIIRS(1)PK HS(-83.86)IAGIIRS(83.86)PK 9 2 629.83701 0.31963 940510 13581 0 0 673000 0 126230 127690 495 392 411 411 5860;5861 6682;6683;6684 57832 35161 Mix4_InSol_TiO2_1 3043 57832 35161 Mix4_InSol_TiO2_1 3043 P16591 P16591 P16591 >sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens GN=FER PE=1 SV=2 0.999429 32.4318 0.683898 6.36195 0.94158 6.3619 0 0 0.999429 32.4318 0.01229 71.857 0.992905 24.4701 0.107216 47.105 1 S DARSVTSMERKER CK1 0.081 0.01229 71.857 _SVTpSMERK_ SVT(0.001)S(0.999)MERK S(-71.86)VT(-32.43)S(32.43)MERK 4 2 509.22537 0.12896 717550 7805 0 0 0 0 321990 387760 496 396 10 10 134 155 1337 838 Mix4_TiO2_1_3 5150 1337 838 Mix4_TiO2_1_3 5150 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.730274 4.3264 0.730274 4.3264 5.12711E-32 211.94 0 0 0.678935 3.25334 4.26462E-10 128.19 0.456017 0 1.91276E-15 145.79 0.499814 0 2.39667E-06 111.39 1 S VFPGNDSTASQDV 5.12711E-32 211.94 _(ac)ADVFPGNDpSTASQDVANR_ ADVFPGNDS(0.73)T(0.27)ASQDVANR ADVFPGNDS(4.33)T(-4.33)AS(-41.9)QDVANR 9 2 993.41547 0.032956 1123200 0.032285 283430 0 0 839780 0 0 0 497 396 13 13 134 155 1334 835 Mix4_InSol_TiO2_1 6280 1337 838 Mix4_TiO2_1_3 5150 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.967356 15.1567 4.71492E-05 -41.9001 5.12711E-32 211.94 0 0 7.31133E-05 -39.6783 4.26462E-10 128.19 0.967356 15.1567 1.91276E-15 145.79 0.000371715 -31.286 2.39667E-06 111.39 1 S GNDSTASQDVANR CK1 0.081 5.12711E-32 211.94 _(ac)ADVFPGNDSTApSQDVANR_ ADVFPGNDS(0.03)T(0.003)AS(0.967)QDVANR ADVFPGNDS(-15.16)T(-24.89)AS(15.16)QDVANR 12 2 993.41547 0.29556 281790 0.0080997 0 0 0 0 0 281790 0 498 396 657 657 2387 2704 22239 13859 Mix4_TiO2_Reinj_2_2 3657 22244 13864 Mix4_TiO2_Reinj_2_1 5493 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.494981 0 0.460682 0 0.00188773 91.836 0.494981 0 1.73627E-06 109.54 2 S SDFEGFSYVNPQF PDK1 0.0001168 1.73627E-06 109.54 _GQPVLpTPPDQLVIANIDQSDFEGFpSYVNPQFVHPILQSAV_ GQPVLT(1)PPDQLVIANIDQS(0.009)DFEGFS(0.495)Y(0.495)VNPQFVHPILQS(0.002)AV GQPVLT(33.15)PPDQLVIANIDQS(-17.88)DFEGFS(0)Y(0)VNPQFVHPILQS(-23.96)AV 25 4 1135.7933 -0.22234 0 0 0 0 0 0 0 0 499 396 319 319 3457;6445;6446;6447 3903;7373;7375;7376 65110 39946 Mix4_TiO2_1_3 1718 32563 20197 Mix4_InSol_TiO2_1 4666 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.988521 19.3506 0.988521 19.3506 0.0950857 48.97 0.984569 18.0486 0.39581 26.704 0.98727 18.8961 0.0200516 62.406 0 0 0.878143 8.57713 0.0182947 66.06 0.954391 13.2068 0.67915 24.072 1 S AGNKVISPSEDRK CK2;ERK/MAPK;Proline-directed 0.0034 0.0182947 66.06 _VIpSPSEDRK_ VIS(0.989)PS(0.011)EDRK VIS(19.35)PS(-19.35)EDRK 3 2 555.76318 -0.65917 4885000 49.435 950390 27081 0 3278800 0 155910 472840 500 396 226 226 5790 6596 57020 34765 Mix4_InSol_TiO2_2 5724 57037 34793 Mix4_TiO2_Reinj_1_4 7521 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.99981 37.2011 0.999259 31.2983 4.61543E-39 237.8 0.790851 10.0985 0.855646 10.791 0.99934 31.8089 1.41018E-50 263.59 0.877833 8.56462 0.022659 61.295 0.99981 37.2011 1.73817E-29 215.97 0.991786 20.8187 1.31385E-15 179.33 1 S NPQWNESFTFKLK 1.41018E-50 263.59 _STLNPQWNEpSFTFK_ STLNPQWNES(1)FTFK S(-180.28)T(-179.46)LNPQWNES(37.2)FT(-37.2)FK 10 2 889.89291 0.17536 30498000 7160400 12392 0 18838000 8998.6 2377400 2100100 501 398 339 339 2002;2355 2267;2665 21781 13554 Mix4_TiO2_Reinj_1_4 9091 21750 13372 Mix4_TiO2_1_4 6704 P17612;P17612-2 P17612 P17612 >sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA PE=1 SV=2;>sp|P17612-2|KAPCA_HUMAN Isoform C(s) of cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA 1 86.2701 1 109.998 9.73493E-34 191.88 0.998947 34.5433 0.362028 44.036 1 86.2701 8.58542E-26 168.78 0.999867 43.0042 0.0194567 62.78 0.999411 35.1645 0.590607 38.457 0.967595 19.522 1.73671 19.522 1 S EEEIRVSINEKCG AURORA;AURORA-1;CK2;PKA 0.020748 9.73493E-34 191.88 _GPGDTSNFDDYEEEEIRVpSINEK_ GPGDTSNFDDYEEEEIRVS(1)INEK GPGDT(-109.65)S(-107.87)NFDDY(-86.27)EEEEIRVS(86.27)INEK 19 3 908.38339 0.59807 43410000 10589000 440660 0 31262000 302700 528550 286870 502 400 228 228 641 737 6118 3569 Mix4_TiO2_1_4 5306 6119 3570 Mix4_TiO2_Reinj_1_6 5011 P17676 P17676 P17676 >sp|P17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta OS=Homo sapiens GN=CEBPB PE=1 SV=2 0.418829 5.53282 0.418829 5.53282 0.780564 49.137 0.0421564 -9.53036 0.0109356 77.475 0 0 0 0 1 S GSLSTSSSSSPPG CK1 0.081 0.0109356 77.475 _AYLGYQAVPSGSSGSLSTSpSSSSPPGTPSPADAK_ AYLGYQAVPS(0.042)GS(0.042)S(0.042)GS(0.042)LS(0.034)T(0.034)S(0.034)S(0.419)S(0.117)S(0.117)S(0.064)PPGT(0.01)PS(0.003)PADAK AY(-38.33)LGY(-38.33)QAVPS(-10.01)GS(-10.01)S(-10.01)GS(-10.01)LS(-10.87)T(-10.87)S(-10.87)S(5.53)S(-5.53)S(-5.53)S(-8.16)PPGT(-16.4)PS(-21.28)PADAK 20 3 1093.4961 0.1243 0 0 0 0 0 0 0 0 503 400 230 230 641 737 6119 3570 Mix4_TiO2_Reinj_1_6 5011 6119 3570 Mix4_TiO2_Reinj_1_6 5011 P17676 P17676 P17676 >sp|P17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta OS=Homo sapiens GN=CEBPB PE=1 SV=2 0.378355 0 0.117153 -5.53282 0.780564 49.137 0.378355 0 0.0109356 77.475 0 0 0 0 1 S LSTSSSSSPPGTP CK1 0.081 0.0109356 77.475 _AYLGYQAVPSGSSGSLSTSSSpSSPPGTPSPADAK_ AYLGYQAVPS(0.003)GS(0.001)S(0.001)GS(0.001)LS(0.005)T(0.015)S(0.015)S(0.042)S(0.136)S(0.378)S(0.378)PPGT(0.024)PS(0.001)PADAK AY(-56.05)LGY(-49.82)QAVPS(-20.49)GS(-26.84)S(-26.84)GS(-26.84)LS(-18.83)T(-13.9)S(-13.9)S(-9.53)S(-4.46)S(0)S(0)PPGT(-12.06)PS(-28.62)PADAK 22 3 1093.4961 -0.36666 0 0 0 0 0 0 0 0 504 400 231 231 641 737 6119 3570 Mix4_TiO2_Reinj_1_6 5011 6119 3570 Mix4_TiO2_Reinj_1_6 5011 P17676 P17676 P17676 >sp|P17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta OS=Homo sapiens GN=CEBPB PE=1 SV=2 0.378355 0 0.0639812 -8.15984 0.780564 49.137 0.378355 0 0.0109356 77.475 0 0 0 0 1 S STSSSSSPPGTPS CK1;Polo box;Proline-directed 0.00405 0.0109356 77.475 _AYLGYQAVPSGSSGSLSTSSSpSSPPGTPSPADAK_ AYLGYQAVPS(0.003)GS(0.001)S(0.001)GS(0.001)LS(0.005)T(0.015)S(0.015)S(0.042)S(0.136)S(0.378)S(0.378)PPGT(0.024)PS(0.001)PADAK AY(-56.05)LGY(-49.82)QAVPS(-20.49)GS(-26.84)S(-26.84)GS(-26.84)LS(-18.83)T(-13.9)S(-13.9)S(-9.53)S(-4.46)S(0)S(0)PPGT(-12.06)PS(-28.62)PADAK 23 3 1093.4961 -0.36666 0 0 0 0 0 0 0 0 505 401 573 573 5329;5330 6069;6070;6071 51785 31701 Mix4_TiO2_Reinj_1_3 7674 51785 31701 Mix4_TiO2_Reinj_1_3 7674 P17812 P17812 P17812 >sp|P17812|PYRG1_HUMAN CTP synthase 1 OS=Homo sapiens GN=CTPS PE=1 SV=2 0.817003 8.31077 0.511882 0.761701 1.12662 22.25 0.817003 8.31077 0.00567097 73.538 0.165861 -4.81216 8.99791E-07 100.33 0.25804 0 0.0530918 56.632 2 S YSDRSGSSSPDSE CAMK2;PKA/AKT 0.00111111 0.00567097 73.538 _SGpSSpSPDSEITELKFPSINHD_ S(0.08)GS(0.817)S(0.123)S(0.517)PDS(0.419)EIT(0.045)ELKFPSINHD S(-10.59)GS(8.31)S(-8.31)S(0.83)PDS(-0.83)EIT(-10.59)ELKFPS(-73.54)INHD 3 3 802.99613 0.03375 574000 56840 0 0 517160 0 0 0 506 401 575 575 5329;5330 6069;6070;6071 51764 31693 Mix4_TiO2_1_3 4557 51764 31693 Mix4_TiO2_1_3 4557 P17812 P17812 P17812 >sp|P17812|PYRG1_HUMAN CTP synthase 1 OS=Homo sapiens GN=CTPS PE=1 SV=2 0.985456 19.0447 0.985456 19.0447 0.000193126 101.52 0.516908 0.831998 0.00567097 73.538 0.502296 4.81216 8.99791E-07 100.33 0.25804 0 0.0530918 56.632 1 S DRSGSSSPDSEIT CK1;Polo box;Proline-directed 0.00405 0.000193126 101.52 _SGSSpSPDSEITELK_ SGSS(0.012)S(0.985)PDS(0.002)EITELK S(-44.08)GS(-34.91)S(-19.04)S(19.04)PDS(-27.13)EIT(-66.1)ELK 5 2 758.82436 0.90458 888920 797240 0 0 0 0 91680 0 507 403 50 50 1329;6784 1498;7762 68781 42177 Mix4_TiO2_Reinj_1_4 4193 12432 7593 Mix4_TiO2_Reinj_1_4 3939 P18031 P18031 P18031 >sp|P18031|PTN1_HUMAN Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens GN=PTPN1 PE=1 SV=1 0.999925 42.386 0.995238 23.2014 0.31812 23.201 0.999925 42.386 0.00383652 71.578 1 S NRYRDVSPFDHSR CAMK2;CK2;PKA/AKT;Proline-directed 0.001764 0.00383652 71.578 _YRDVpSPFDHSR_ YRDVS(1)PFDHSR Y(-47.61)RDVS(42.39)PFDHS(-42.39)R 5 2 729.81172 -0.038194 550590 19540 0 0 531050 0 0 0 508 407 1737 1737 1800 2031 16554 9981 Mix4_TiO2_Reinj_1_1 7111 16554 9981 Mix4_TiO2_Reinj_1_1 7111 P18583-9;P18583-5;P18583;P18583-7;P18583-4;P18583-3;P18583-10;P18583-2;P18583-6 P18583-9 P18583-9 >sp|P18583-9|SON_HUMAN Isoform I of Protein SON OS=Homo sapiens GN=SON;>sp|P18583-5|SON_HUMAN Isoform D of Protein SON OS=Homo sapiens GN=SON;>sp|P18583|SON_HUMAN Protein SON OS=Homo sapiens GN=SON PE=1 SV=4;>sp|P18583-7|SON_HUMAN Isoform G of Protein SON 1 95.6848 1 86.676 0.00320223 86.676 1 95.6848 0.00127801 95.685 1 S TLAALLSPKESSG CDK1;CK2;GSK3;Proline-directed 0.0057 0.00127801 95.685 _ESDQTLAALLpSPK_ ESDQTLAALLS(1)PK ES(-95.68)DQT(-95.68)LAALLS(95.68)PK 11 2 726.85272 0.16477 117780 23311 0 0 94474 0 0 0 509 409 67 67 3265;3266;6658 3700;3701;7623 30860 19153 Mix4_TiO2_Reinj_1_5 2479 30872 19169 Mix4_TiO2_Reinj_1_5 2161 P19338 P19338 P19338 >sp|P19338|NUCL_HUMAN Nucleolin OS=Homo sapiens GN=NCL PE=1 SV=3 0.995207 23.1732 0.993212 21.6532 0.235741 35.878 0.5 0 0.999134 8.6234 0.995207 23.1732 0.00104095 83.921 0.982407 17.4696 0.00638103 65.218 0.99213 21.0058 0.0291801 53.647 1 S AKKVVVSPTKKVA CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 0.00104095 83.921 _KVVVpSPTK_ KVVVS(0.995)PT(0.005)K KVVVS(23.17)PT(-23.17)K 5 2 469.25954 0.072316 3349100 118370 10229 0 1415600 0 855200 949760 510 416 1193 1193 2731 3112 25790 15941 Mix4_TiO2_Reinj_1_1 6155 25788 15937 Mix4_TiO2_1_1 5433 P20020;P20020-4;P20020-3;P20020-6 P20020 P20020 >sp|P20020|AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens GN=ATP2B1 PE=1 SV=3;>sp|P20020-4|AT2B1_HUMAN Isoform CIII of Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens GN=ATP2B1;>sp|P20020-3|AT2B1_HUMAN Isoform CI of 1 80.8697 1 97.7561 9.49639E-08 115.89 0 0 1 80.8697 2.35684E-07 112.61 0 0 0 0 1 S EFRIEDSEPHIPL 9.49639E-08 115.89 _IEDpSEPHIPLIDDTDAEDDAPTKR_ IEDS(1)EPHIPLIDDTDAEDDAPTKR IEDS(80.87)EPHIPLIDDT(-80.87)DAEDDAPT(-112.61)KR 4 3 924.74644 0.3133 1466300 390740 0 0 1075600 0 0 0 511 416 1249 1249 5127 5832 49600 30293 Mix4_TiO2_Reinj_1_1 7221 49599 30292 Mix4_TiO2_Reinj_1_1 6204 P20020;P20020-4;P20020-3;P20020-6 P20020 P20020 >sp|P20020|AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens GN=ATP2B1 PE=1 SV=3;>sp|P20020-4|AT2B1_HUMAN Isoform CIII of Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens GN=ATP2B1;>sp|P20020-3|AT2B1_HUMAN Isoform CI of 0.98164 17.2829 0.000382642 -33.4719 0.416255 33.472 0 0 0.98164 17.2829 6.94981E-10 122.39 9.5459E-06 -50.1403 0.0970456 50.14 0 0 1 S TSSSPGSPLHSLE CK1;ERK/MAPK;GSK3;Proline-directed 0.0025 6.94981E-10 122.39 _SATSSSPGpSPLHSLETSL_ SATSSSPGS(0.982)PLHS(0.018)LETSL S(-80.57)AT(-79.85)S(-67.14)S(-59.63)S(-51.78)PGS(17.28)PLHS(-17.28)LET(-62.56)S(-69.55)L 9 2 919.4144 -0.17828 272210 0 0 0 272210 0 0 0 512 416 1257 1257 5127 5832 49597 30290 Mix4_InSol_TiO2_1 7241 49599 30292 Mix4_TiO2_Reinj_1_1 6204 P20020;P20020-4;P20020-3;P20020-6 P20020 P20020 >sp|P20020|AT2B1_HUMAN Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens GN=ATP2B1 PE=1 SV=3;>sp|P20020-4|AT2B1_HUMAN Isoform CIII of Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens GN=ATP2B1;>sp|P20020-3|AT2B1_HUMAN Isoform CI of 0.985937 18.5703 0.851101 7.71962 0.416255 33.472 0 0 0.930846 11.2911 6.94981E-10 122.39 0.985937 18.5703 0.0970456 50.14 0 0 1 S LHSLETSL_____ CK1;NEK6;PLK1 0.033462 6.94981E-10 122.39 _SATSSSPGSPLHSLETpSL_ SATSSSPGSPLHSLET(0.014)S(0.986)L S(-50.14)AT(-50.14)S(-50.14)S(-50.14)S(-50.14)PGS(-50.14)PLHS(-35.13)LET(-18.57)S(18.57)L 17 2 919.4144 -0.1738 234380 35042 0 0 159300 0 40044 0 513 420 23 23 238 273 2376 1507 Mix4_TiO2_1_3 3049 2376 1507 Mix4_TiO2_1_3 3049 P20700 P20700 P20700 >sp|P20700|LMNB1_HUMAN Lamin-B1 OS=Homo sapiens GN=LMNB1 PE=1 SV=2 0.998313 27.733 0.998313 27.733 0.00936512 74.379 0.000238511 -33.8196 0.173363 33.82 0 0 0 0 1 S GPTTPLSPTRLSR CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00936512 74.379 _AGGPTTPLpSPTR_ AGGPTTPLS(0.998)PT(0.002)R AGGPT(-68.83)T(-53.58)PLS(27.73)PT(-27.73)R 9 2 617.79501 0.17685 43331 43331 0 0 0 0 0 0 514 422 101 101 2310;3761;3762 2613;4244;4245 35552 21973 Mix4_TiO2_Reinj_1_4 5692 35532 21942 Mix4_TiO2_Reinj_1_2 5324 P21796 P21796 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens GN=VDAC1 PE=1 SV=2 0.795294 8.43447 0.0963097 -8.76424 4.22379E-09 166.99 0 0 0.795294 8.43447 4.21292E-09 167.02 0 0 0.42772 0 4.13106E-05 114.67 0.018914 -13.0153 0.00168515 89.982 1 S LKLTFDSSFSPNT 4.21292E-09 167.02 _LTFDpSSFSPNTGKK_ LT(0.001)FDS(0.795)S(0.114)FS(0.088)PNT(0.001)GKK LT(-28.03)FDS(8.43)S(-8.43)FS(-9.55)PNT(-28.03)GKK 5 3 536.91503 0.075951 293690 0.47355 0 0 0 293690 0 0 0 515 422 102 102 2310;3761;3762 2613;4244;4245 35548 21964 Mix4_TiO2_1_4 5027 35532 21942 Mix4_TiO2_Reinj_1_2 5324 P21796 P21796 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens GN=VDAC1 PE=1 SV=2 0.724593 8.76424 0.724593 8.76424 4.22379E-09 166.99 0 0 0.56243 1.37186 4.21292E-09 167.02 0 0 0.42772 0 4.13106E-05 114.67 0.32749 -0.631206 0.00168515 89.982 1 S KLTFDSSFSPNTG CK1;PLK1 0.033462 4.21292E-09 167.02 _LTFDSpSFSPNTGKK_ LT(0.048)FDS(0.096)S(0.725)FS(0.083)PNT(0.048)GKK LT(-11.79)FDS(-8.76)S(8.76)FS(-9.4)PNT(-11.79)GKK 6 3 536.91503 0.36114 630110 1.016 78971 0 0 551140 0 0 0 516 422 104 104 2310;3761;3762 2613;4244;4245 35532 21942 Mix4_TiO2_Reinj_1_2 5324 35532 21942 Mix4_TiO2_Reinj_1_2 5324 P21796 P21796 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens GN=VDAC1 PE=1 SV=2 0.99941 33.5632 0.998585 28.5873 4.22379E-09 166.99 0 0 0.99941 33.5632 4.21292E-09 167.02 0 0 0.945899 14.7497 4.13106E-05 114.67 0.468315 0.171573 0.00168515 89.982 1 S TFDSSFSPNTGKK CK1;Proline-directed 0.05 4.21292E-09 167.02 _LTFDSSFpSPNTGK_ LTFDSSFS(0.999)PNTGK LT(-141.55)FDS(-66.21)S(-38.23)FS(33.56)PNT(-33.56)GK 8 2 740.82142 0.067734 8640100 13.931 1651400 0 0 5533200 0 1455500 0 517 422 57 57 6633 7592 67246 41298 Mix4_TiO2_Reinj_1_2 2162 67244 41294 Mix4_TiO2_1_2 1599 P21796 P21796 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens GN=VDAC1 PE=1 SV=2 0.999993 52.9182 0.999886 39.4933 0.0170313 66.084 0.997922 29.8241 0.341365 29.824 0.999993 52.9182 0.0361178 58.038 0.940468 14.9962 0.747323 14.996 0 0 1 S TTKVTGSLETKYR 0.0170313 66.084 _VTGpSLETK_ VTGS(1)LETK VT(-52.92)GS(52.92)LET(-58.04)K 4 2 457.71517 -0.16439 513990 3.78 82209 8664.1 0 408540 0 14572 0 518 424 124 124 5067 5761 48989 29920 Mix4_TiO2_Reinj_1_2 4130 48989 29920 Mix4_TiO2_Reinj_1_2 4130 P22087 P22087 P22087 >sp|P22087|FBRL_HUMAN rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens GN=FBL PE=1 SV=2 0.985458 18.3113 0.985458 18.3113 0.0481667 54.442 0 0 0 0 1 S YGEKRVSISEGDD AURORA;AURORA-1;AURORA-A;CK2;PKA 0.006142092 0.0481667 54.442 _RVpSISEGDDKIEYR_ RVS(0.985)IS(0.015)EGDDKIEYR RVS(18.31)IS(-18.31)EGDDKIEY(-54.44)R 3 3 582.94012 -0.11436 88749 0 0 0 88749 0 0 0 519 425 27 27 1927;6044;6045 2178;6893;6895 59709 36229 Mix4_TiO2_1_4 5407 17676 10565 Mix4_TiO2_1_4 5320 P22234 P22234 P22234 >sp|P22234|PUR6_HUMAN Multifunctional protein ADE2 OS=Homo sapiens GN=PAICS PE=1 SV=3 1 147.367 1 147.367 2.10967E-12 188.32 0 0 1 134.469 8.44461E-08 170.06 0 0 1 S VYELLDSPGKVLL CDK1;CDK2;NEK6;Proline-directed 0.0057 2.10967E-12 188.32 _TKEVYELLDpSPGK_ TKEVYELLDS(1)PGK T(-158.51)KEVY(-147.37)ELLDS(147.37)PGK 10 2 779.87365 -0.99136 1839900 17.859 465190 0 0 1374700 0 0 0 520 429 339 339 2435 2761 22851 14277 Mix4_TiO2_1_4 6187 22854 14291 Mix4_TiO2_1_4 6973 P22694;P22694-2;P22694-6;P22694-7;P22694-5;P22694-3;P22694-4 P22694 P22694 >sp|P22694|KAPCB_HUMAN cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens GN=PRKACB PE=1 SV=2;>sp|P22694-2|KAPCB_HUMAN Isoform Beta2 of cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens GN=PRKACB;>sp|P22694-6|KAPCB_HUMA 0.997461 25.9429 0.997461 25.9429 3.37435E-47 230.12 0 0 0.894784 9.29634 1.7007E-17 149.35 0.49657 0 0.79309 32.301 0 0 0.457157 1.86983 1.83969 8.7186 1 S EEDIRVSITEKCA AURORA;AURORA-1;CK2;PKA 0.020748 3.37435E-47 230.12 _GSGDTSNFDDYEEEDIRVpSITEK_ GSGDTSNFDDYEEEDIRVS(0.997)IT(0.003)EK GS(-164.28)GDT(-142.61)S(-126.99)NFDDY(-85.7)EEEDIRVS(25.94)IT(-25.94)EK 19 3 896.03951 0.56366 3913900 1204200 0 0 2709700 0 0 0 521 431 100 100 3086 3507 29374 18322 Mix4_TiO2_Reinj_1_4 2534 29374 18322 Mix4_TiO2_Reinj_1_4 2534 P23193;P23193-2 P23193 P23193 >sp|P23193|TCEA1_HUMAN Transcription elongation factor A protein 1 OS=Homo sapiens GN=TCEA1 PE=1 SV=2;>sp|P23193-2|TCEA1_HUMAN Isoform 2 of Transcription elongation factor A protein 1 OS=Homo sapiens GN=TCEA1 0.999884 39.3502 0.999884 39.3502 0.00123742 91.074 1 S AITSQNSPEAREE CK1;Proline-directed 0.05 0.00123742 91.074 _KKEPAITSQNpSPEAR_ KKEPAITSQNS(1)PEAR KKEPAIT(-72.63)S(-39.35)QNS(39.35)PEAR 11 3 579.284 1.2886 68211 0 0 0 68211 0 0 0 522 434 224 224 798;3154 905;3580 7625 4506 Mix4_TiO2_2_6 3852 7626 4509 Mix4_TiO2_Reinj_1_2 4934 P23396 P23396 P23396 >sp|P23396|RS3_HUMAN 40S ribosomal protein S3 OS=Homo sapiens GN=RPS3 PE=1 SV=2 0.737479 5.1995 0.117183 -5.75977 1.67414E-09 172.39 0.737479 5.1995 0.0204282 60.895 0.164817 -6.53966 2.72828E-13 178.6 0 0 0.0196366 -13.9729 0.000269649 83.674 0.0768367 -9.94849 0.00741044 76.335 1 S LPTTPISEQKGGK CK1 0.143 2.72828E-13 178.6 _DEILPTTPIpSEQK_ DEILPT(0.04)T(0.223)PIS(0.737)EQK DEILPT(-12.68)T(-5.2)PIS(5.2)EQK 10 2 775.87111 0.028477 26969 0.034464 0 26969 0 0 0 0 0 523 435 427 427 1615 1813 14870 9015 Mix4_TiO2_Reinj_1_4 5129 14867 9009 Mix4_TiO2_1_3 4406 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 1 45.2917 1 46.3704 0.0181731 64.693 1 45.2917 0.119 45.292 0 0 0 0 1 S SVKEKFSFEPKIR AURORA 0.038874 0.0181731 64.693 _EKFpSFEPK_ EKFS(1)FEPK EKFS(45.29)FEPK 4 2 546.24409 0.11732 2819400 485710 0 0 2333700 0 0 0 524 435 398 398 4757 5404 45367 27740 Mix4_TiO2_Reinj_1_4 9093 45367 27740 Mix4_TiO2_Reinj_1_4 9093 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 0.261184 0 0 0 0.261184 0 0.00604194 78.764 1 S VDSPDDSTLSESA CK1 0.143 0.00604194 78.764 _QTPVDSPDDpSTLSESANQVFLGFTYVAPSVLESVK_ QT(0.047)PVDS(0.148)PDDS(0.261)T(0.261)LS(0.261)ES(0.021)ANQVFLGFTYVAPSVLESVK QT(-7.47)PVDS(-2.45)PDDS(0)T(0)LS(0)ES(-10.9)ANQVFLGFT(-45.76)Y(-56.31)VAPS(-70.59)VLES(-73.25)VK 10 3 1269.9345 1.4068 0 0 0 0 0 0 0 0 525 435 401 401 4757 5404 45367 27740 Mix4_TiO2_Reinj_1_4 9093 45367 27740 Mix4_TiO2_Reinj_1_4 9093 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 0.261184 0 0 0 0.261184 0 0.00604194 78.764 1 S PDDSTLSESANQV CK1 0.081 0.00604194 78.764 _QTPVDSPDDpSTLSESANQVFLGFTYVAPSVLESVK_ QT(0.047)PVDS(0.148)PDDS(0.261)T(0.261)LS(0.261)ES(0.021)ANQVFLGFTYVAPSVLESVK QT(-7.47)PVDS(-2.45)PDDS(0)T(0)LS(0)ES(-10.9)ANQVFLGFT(-45.76)Y(-56.31)VAPS(-70.59)VLES(-73.25)VK 13 3 1269.9345 1.4068 0 0 0 0 0 0 0 0 526 435 447 447 6167;6168 7041;7042;7043 61113 37030 Mix4_TiO2_Reinj_1_3 2568 61126 37047 Mix4_TiO2_1_4 7225 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 1 103.679 1 74.7355 2.64526E-12 143.15 1 73.9373 0.0696267 73.937 1 103.679 1.37148E-08 119.21 0.994546 23.0669 0.0207192 64.156 0.710178 6.83003 0.220608 38.525 1 S SPRTPVSPVKFSP CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.64526E-12 143.15 _TPVpSPVK_ TPVS(1)PVK T(-103.68)PVS(103.68)PVK 4 2 404.20424 0.033662 5967900 953170 405580 0 3665000 0 909020 35118 527 435 452 452 6168 7042;7043 61157 37059 Mix4_TiO2_Reinj_1_4 8305 61153 37054 Mix4_TiO2_1_3 7711 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 1 75.8094 1 91.016 1.15102E-08 122.11 0 0 1 75.8094 0.000804928 92.633 0.010631 -19.0315 0.0207192 64.156 0.142467 -6.97651 0.220608 38.525 2 S VSPVKFSPGDFWG CK2;Proline-directed 0.05 1.15102E-08 122.11 _TPVpSPVKFpSPGDFWGR_ TPVS(1)PVKFS(1)PGDFWGR T(-42.7)PVS(42.7)PVKFS(75.81)PGDFWGR 9 3 646.28466 -0.51346 915800 167450 0 0 748340 0 0 0 528 437 3 3 498;499 564;565 4631 2811 Mix4_TiO2_Reinj_1_6 4811 4631 2811 Mix4_TiO2_Reinj_1_6 4811 P23528 P23528 P23528 >sp|P23528|COF1_HUMAN Cofilin-1 OS=Homo sapiens GN=CFL1 PE=1 SV=3 1 84.3699 0.999998 57.4145 0.0120837 69.468 0.999998 56.3214 0.0204621 59.31 1 84.3699 0.000720301 106.86 0 0 1 74.2447 0.00518908 84.293 1 69.0919 0.00460848 86.376 1 S ____MASGVAVSD 0.000720301 106.86 _(ac)ApSGVAVSDGVIK_ AS(1)GVAVSDGVIK AS(84.37)GVAVS(-84.37)DGVIK 2 2 612.79722 -0.12699 4956100 253040 171800 0 1015300 0 1931200 1584700 529 439 106 106 769;6734 876;7707 68280 41852 Mix4_TiO2_1_2 4922 68280 41852 Mix4_TiO2_1_2 4922 P24534 P24534 P24534 >sp|P24534|EF1B_HUMAN Elongation factor 1-beta OS=Homo sapiens GN=EEF1B2 PE=1 SV=3 0.998202 29.1243 0.998202 29.1243 2.43376E-06 102.03 0 0 0.979391 17.6916 2.82321E-06 99.448 0 0 0 0 0 0 1 S DIDLFGSDDEEES CK2;NEK6 0.076 2.43376E-06 102.03 _YGPADVEDTTGSGATDSKDDDDIDLFGpSDDEEESEEAKR_ YGPADVEDTTGSGATDS(0.001)KDDDDIDLFGS(0.998)DDEEESEEAKR Y(-45.99)GPADVEDT(-38.06)T(-38.06)GS(-43.22)GAT(-43.22)DS(-29.12)KDDDDIDLFGS(29.12)DDEEES(-38.4)EEAKR 28 4 1065.9279 0.0022725 2323400 309300 0 0 2014100 0 0 0 530 439 112 112 769;6734 876;7707 7426 4385 Mix4_TiO2_Reinj_1_2 5743 68280 41852 Mix4_TiO2_1_2 4922 P24534 P24534 P24534 >sp|P24534|EF1B_HUMAN Elongation factor 1-beta OS=Homo sapiens GN=EEF1B2 PE=1 SV=3 0.5 0 0.000144426 -38.3957 2.43376E-06 102.03 0 0 0.5 0 2.82321E-06 99.448 0 0 0 0 0 0 1 S SDDEEESEEAKRL 2.43376E-06 102.03 _DDDDIDLFGpSDDEEESEEAKR_ DDDDIDLFGS(0.5)DDEEES(0.5)EEAKR DDDDIDLFGS(0)DDEEES(0)EEAKR 16 3 836.98518 0.13733 105400 0 0 0 105400 0 0 0 531 440 103 103 2454;2791 2783;3181 23053 14409 Mix4_TiO2_Reinj_1_4 7962 23053 14409 Mix4_TiO2_Reinj_1_4 7962 P24864;P24864-3;P24864-2 P24864 P24864 >sp|P24864|CCNE1_HUMAN G1/S-specific cyclin-E1 OS=Homo sapiens GN=CCNE1 PE=1 SV=2;>sp|P24864-3|CCNE1_HUMAN Isoform E-S of G1/S-specific cyclin-E1 OS=Homo sapiens GN=CCNE1;>sp|P24864-2|CCNE1_HUMAN Isoform E1S of G1/S-specific cyclin-E1 OS=Homo sapiens GN=CC 1 145.857 1 104.627 2.45155E-06 111.24 0 0 1 145.857 1.91104E-08 159.99 1 S IAPSRGSPLPVLS CK1;PKA;Proline-directed 0.042 1.91104E-08 159.99 _GpSPLPVLSWANR_ GS(1)PLPVLSWANR GS(145.86)PLPVLS(-145.86)WANR 2 2 688.83975 0.0052768 2917200 819230 0 0 2098000 0 0 0 532 440 100 100 2791 3181 26787 16755 Mix4_TiO2_1_5 7016 26785 16752 Mix4_TiO2_1_4 7147 P24864;P24864-3;P24864-2 P24864 P24864 >sp|P24864|CCNE1_HUMAN G1/S-specific cyclin-E1 OS=Homo sapiens GN=CCNE1 PE=1 SV=2;>sp|P24864-3|CCNE1_HUMAN Isoform E-S of G1/S-specific cyclin-E1 OS=Homo sapiens GN=CCNE1;>sp|P24864-2|CCNE1_HUMAN Isoform E1S of G1/S-specific cyclin-E1 OS=Homo sapiens GN=CC 0.446332 0 0.446332 0 2.45155E-06 111.24 0 0 0.0786271 -10.6886 2.66456E-06 110.64 1 S PRIIAPSRGSPLP 2.45155E-06 111.24 _IIAPpSRGSPLPVLSWANR_ IIAPS(0.446)RGS(0.446)PLPVLS(0.107)WANR IIAPS(0)RGS(0)PLPVLS(-6.19)WANR 5 3 672.02597 -0.17225 0 0 0 0 0 0 0 0 533 444 250 250 1819 2053;2054 16690 10043 Mix4_TiO2_Reinj_1_6 3159 16682 10040 Mix4_TiO2_Reinj_1_6 2248 P25788;P25788-2 P25788 P25788 >sp|P25788|PSA3_HUMAN Proteasome subunit alpha type-3 OS=Homo sapiens GN=PSMA3 PE=1 SV=2;>sp|P25788-2|PSA3_HUMAN Isoform 2 of Proteasome subunit alpha type-3 OS=Homo sapiens GN=PSMA3 1 86.3492 1 113.383 3.043E-16 191.54 1 86.3492 3.28576E-39 242.18 1 103.588 4.14789E-23 213.9 1 144.75 4.28995E-30 229.38 1 S LKEEDESDDDNM_ CK2 0.117 3.28576E-39 242.18 _ESLKEEDEpSDDDNM_ ESLKEEDES(1)DDDNM ES(-86.35)LKEEDES(86.35)DDDNM 9 2 868.29804 0.091634 1757700 215790 0 0 619230 0 457510 465200 534 445 139 139 3031 3445 28921 17991 Mix4_TiO2_Reinj_1_6 2213 28920 17989 Mix4_TiO2_Reinj_1_6 1927 P26373 P26373 P26373 >sp|P26373|RL13_HUMAN 60S ribosomal protein L13 OS=Homo sapiens GN=RPL13 PE=1 SV=4 0.987908 19.1223 0.112859 -8.95457 0.12758 35.787 0 0 0.987908 19.1223 0.00276047 73.343 1 S APKKGDSSAEELK CK2 0.117 0.00276047 73.343 _KGDpSSAEELK_ KGDS(0.988)S(0.012)AEELK KGDS(19.12)S(-19.12)AEELK 4 2 572.2501 -0.34078 53376 0.036986 0 0 0 53376 0 0 0 535 445 140 140 3031 3445 28920 17989 Mix4_TiO2_Reinj_1_6 1927 28920 17989 Mix4_TiO2_Reinj_1_6 1927 P26373 P26373 P26373 >sp|P26373|RL13_HUMAN 60S ribosomal protein L13 OS=Homo sapiens GN=RPL13 PE=1 SV=4 0.991547 20.6929 0.887141 8.95457 0.12758 35.787 0 0 0.991547 20.6929 0.00276047 73.343 1 S PKKGDSSAEELKL CK2 0.117 0.00276047 73.343 _KGDSpSAEELK_ KGDS(0.008)S(0.992)AEELK KGDS(-20.69)S(20.69)AEELK 5 2 572.2501 -0.37196 356610 0.2471 30802 0 0 325800 0 0 0 536 445 106 106 4108;5780 4678;6586 38890 23851 Mix4_TiO2_1_6 2312 38891 23852 Mix4_TiO2_Reinj_1_6 2878 P26373 P26373 P26373 >sp|P26373|RL13_HUMAN 60S ribosomal protein L13 OS=Homo sapiens GN=RPL13 PE=1 SV=4 0.946436 12.4915 0.946436 12.4915 0.0187102 62.912 0.903182 9.78679 0.00232683 90.775 0.86885 8.34259 0.0327616 57.029 0 0 1 S PRRRNKSTESLQA CAMK2;PKA/AKT 0.001764 0.00232683 90.775 _NKpSTESLQANVQR_ NKS(0.946)T(0.053)ESLQANVQR NKS(12.49)T(-12.49)ES(-36.01)LQANVQR 3 2 777.86723 -0.39976 199630 0.32858 37080 0 0 129660 0 32884 0 537 445 109 109 4108;5780 4678;6586 56943 34726 Mix4_TiO2_1_6 2439 38891 23852 Mix4_TiO2_Reinj_1_6 2878 P26373 P26373 P26373 >sp|P26373|RL13_HUMAN 60S ribosomal protein L13 OS=Homo sapiens GN=RPL13 PE=1 SV=4 0.81316 8.80437 0.81316 8.80437 0.0187102 62.912 0.00195531 -26.6456 0.00232683 90.775 0.00389135 -23.4884 0.0327616 57.029 0 0 1 S RNKSTESLQANVQ CK1 0.081 0.00232683 90.775 _STEpSLQANVQR_ S(0.08)T(0.107)ES(0.813)LQANVQR S(-10.08)T(-8.8)ES(8.8)LQANVQR 4 2 656.79828 -0.25633 11908 0.0196 11908 0 0 0 0 0 0 538 445 97 97 6027 6874 59560 36145 Mix4_TiO2_Reinj_1_6 4486 59560 36145 Mix4_TiO2_Reinj_1_6 4486 P26373 P26373 P26373 >sp|P26373|RL13_HUMAN 60S ribosomal protein L13 OS=Homo sapiens GN=RPL13 PE=1 SV=4 1 71.3153 1 64.4446 0.00669029 64.445 0 0 1 71.3153 0.00392748 71.351 0.999995 53.4445 0.0298191 53.444 0 0 1 S ARTIGISVDPRRR CK1 0.143 0.00392748 71.351 _TIGIpSVDPR_ TIGIS(1)VDPR T(-71.32)IGIS(71.32)VDPR 5 2 519.25499 -0.10262 1282100 136.73 236220 0 0 774090 0 271820 0 539 447 141 141 1663 1868 15282 9220 Mix4_InSol_TiO2_1 2384 15283 9221 Mix4_InSol_Tio2_Reinj_1 2417 P26599-2;P26599 P26599-2 P26599-2 >sp|P26599-2|PTBP1_HUMAN Isoform PTB2 of Polypyrimidine tract-binding protein 1 OS=Homo sapiens GN=PTBP1;>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 OS=Homo sapiens GN=PTBP1 PE=1 SV=1 0.863992 8.02994 0 0 0.863992 8.02994 0.0127195 68.319 0.776123 5.62897 0.00580133 82.095 1 S ELKTDSSPNQARA Polo box;Proline-directed 0.00405 0.00580133 82.095 _ELKTDSpSPNQAR_ ELKTDS(0.136)S(0.864)PNQAR ELKT(-47.45)DS(-8.03)S(8.03)PNQAR 7 2 713.32212 0.37092 156040 0 0 0 0 0 82592 73445 540 451;452 563;547 563 1718;6163;6164 1933;7036;7037;7038 61036 36998 Mix4_TiO2_1_3 3321 61023 36985 Mix4_InSol_TiO2_1 4310 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.987017 18.8211 0.987017 18.8211 1.51654E-12 139.48 0.000145768 -38.2739 0.240656 38.274 0.8919 9.20745 5.53384E-26 197.16 0.896566 9.38647 1.35382E-33 217.99 0.849505 8.25582 1.13971E-06 115.94 1 S QRTPVASTHSISS CK1 0.143 1.35382E-33 217.99 _TPVApSTHSISSAATPDR_ TPVAS(0.987)T(0.013)HSISSAATPDR T(-54.59)PVAS(18.82)T(-18.82)HS(-45.18)IS(-62.47)S(-61.15)AAT(-99.86)PDR 5 2 889.40945 0.56106 2636200 644760 0 0 1532200 0 253620 205630 541 451;452 566;550 566 1718;6163;6164 1933;7036;7037;7038 61034 36996 Mix4_TiO2_1_3 3205 61023 36985 Mix4_InSol_TiO2_1 4310 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.784386 8.62418 0.784386 8.62418 1.51654E-12 139.48 0.000145768 -38.2739 0.240656 38.274 0.629334 0.554538 0.118179 46.637 0.557182 1.44342 2.54114E-07 117.62 0.989571 19.2833 1.9404E-06 114.42 1 S PVASTHSISSAAT CK1 0.081 1.35382E-33 217.99 _TPVASTHpSISSAATPDR_ TPVAS(0.108)T(0.108)HS(0.784)ISSAATPDR T(-42.41)PVAS(-8.62)T(-8.62)HS(8.62)IS(-35.57)S(-54.08)AAT(-73.45)PDR 8 3 593.2754 -0.21725 124010 63874 0 0 0 0 0 60134 542 451;452 569;553 569 1718;6163;6164 1933;7036;7037;7038 61091 37012 Mix4_TiO2_Reinj_1_3 4148 61023 36985 Mix4_InSol_TiO2_1 4310 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.339946 0 0.0297456 -20.0736 1.36614E-20 188.95 0.0174238 -17.4991 0.240656 38.274 0.339946 0 5.53384E-26 197.16 0.0352488 -11.7288 2.54114E-07 117.62 0.152709 -5.56299 1.13971E-06 115.94 1 S STHSISSAATPDR CK1 0.081 1.35382E-33 217.99 _TPVASTHSIpSSAATPDRIR_ TPVAST(0.001)HS(0.046)IS(0.34)S(0.34)AAT(0.273)PDRIR T(-73.09)PVAS(-35.13)T(-27.11)HS(-8.7)IS(0)S(0)AAT(-0.95)PDRIR 11 3 683.00379 0.62677 0 0 0 0 0 0 0 0 543 451;452 492;476 492 2266;2267 2563;2564;2565 20908 12827 Mix4_InSol_Tio2_Reinj_1 6005 20907 12826 Mix4_InSol_TiO2_1 6038 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.999976 46.1789 0.954217 13.1895 1.58336 17.153 0 0 0.999578 33.7481 0.15096 41.844 0.999649 34.5407 0.000309755 89.57 0.999976 46.1789 0.00752079 72.05 1 S KGIAPASPMLGNA ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000309755 89.57 _GIAPApSPMLGNASNPNKADIPER_ GIAPAS(1)PMLGNASNPNKADIPER GIAPAS(46.18)PMLGNAS(-46.18)NPNKADIPER 6 2 1200.5725 -0.027368 3895700 90819 0 0 1441300 0 1029400 1334200 544 451;452 624;608 624 2477;5667 2815;6453 55441 33950 Mix4_InSol_TiO2_1 4707 55441 33950 Mix4_InSol_TiO2_1 4707 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.999889 39.6995 0.998118 27.2583 0.00120444 87.976 0 0 0.99845 28.1109 0.0023063 101.75 0.999889 39.6995 0.00402956 111.33 0.990211 20.0864 0.000825778 80.804 1 S QTRSRGSTNLFSK CK1;PKA 0.042 0.00402956 111.33 _SRGpSTNLFSK_ SRGS(1)TNLFSK S(-54.19)RGS(39.7)T(-39.7)NLFS(-111.33)K 4 2 588.77408 -0.16069 10760000 1423400 0 0 6393300 0 1375500 1567600 545 451;452;1430;1713 238;238;218;219 3362 3803 31688 19611 Mix4_TiO2_Reinj_1_4 7848 31677 19590 Mix4_TiO2_1_3 7130 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6;Q96L34;Q96L34-2;Q9P0L2;Q9P0L2-3;Q9P0L2-2 P27448;P27448-7;Q96L34;Q9P0L2 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.597975 1.72431 0.563853 1.13282 5.47474E-32 209.73 0.000137035 -38.6311 0.000479152 90.715 0.597975 1.72431 7.64911E-26 176.24 2.9914E-07 -65.2413 1.35075E-10 132.64 8.35275E-06 -50.7817 0.00016147 96.142 1 S LDTFCGSPPYAAP CK1;Proline-directed 0.05 5.47474E-32 209.73 _LDTFCGpSPPYAAPELFQGK_ LDT(0.402)FCGS(0.598)PPYAAPELFQGK LDT(-1.72)FCGS(1.72)PPY(-55.7)AAPELFQGK 7 3 726.65863 0.08234 1161500 154370 0 0 1007100 0 0 0 546 451;452 666;650 666 4378;5672 4978;6459 41543 25534 Mix4_TiO2_Reinj_1_3 1422 41543 25534 Mix4_TiO2_Reinj_1_3 1422 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 1 97.0543 1 3.81389 0.68115 3.8139 1 97.0543 0.00147657 97.054 0 0 0 0 1 S GSSRNVSAEQKDE CAMK2;CK1 0.042 0.00147657 97.054 _NVpSAEQKDENK_ NVS(1)AEQKDENK NVS(97.05)AEQKDENK 3 2 671.28775 0.16104 240020 0.5106 20640 0 0 219380 0 0 0 547 451;452 606;590 606 5051;5913 5745;6744;6745 48829 29841 Mix4_InSol_TiO2_1 5535 48830 29843 Mix4_InSol_Tio2_Reinj_1 5480 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.973536 16.9517 0.848845 7.73025 0.0190009 61.352 0.973536 16.9517 0.361316 44.07 0.800258 7.01514 0.0204244 61.926 1 S YNGPPASPSLSHE ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.0204244 61.926 _RTATYNGPPApSPSLSHEATPLSQTR_ RT(0.002)AT(0.002)Y(0.002)NGPPAS(0.974)PS(0.02)LSHEATPLSQTR RT(-26.54)AT(-26.54)Y(-26.54)NGPPAS(16.95)PS(-16.95)LS(-37.26)HEAT(-40.8)PLS(-44.07)QT(-44.07)R 11 3 907.09937 -0.7236 441210 0 0 0 0 0 244390 196820 548 451;452 442;426 442 5080 5777 49135 30014 Mix4_TiO2_Reinj_1_3 6054 49135 30014 Mix4_TiO2_Reinj_1_3 6054 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.99856 28.5864 0.851873 7.59742 0.0128414 69.616 0 0 0.99856 28.5864 1.16808E-06 114.81 0 0 0 0 1 S QKQRRYSDHAGPA CAMK2;PKA 0.004788 1.16808E-06 114.81 _RYpSDHAGPAIPSVVAYPK_ RY(0.001)S(0.999)DHAGPAIPSVVAYPK RY(-28.59)S(28.59)DHAGPAIPS(-42.48)VVAY(-60.27)PK 3 2 1004.488 -0.34788 4800400 689140 0 0 4111300 0 0 0 549 451;452 662;646 662 5672 6459 55572 34057 Mix4_TiO2_Reinj_1_3 1401 55572 34057 Mix4_TiO2_Reinj_1_3 1401 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.998807 29.228 0.998807 29.228 0.0811761 43.898 0 0 0 0 1 S GRYEGSSRNVSAE GSK3 0.081 0.0811761 43.898 _pSRNVSAEQKDENK_ S(0.999)RNVS(0.001)AEQKDENK S(29.23)RNVS(-29.23)AEQKDENK 1 2 792.85432 0.26726 117300 0 0 0 117300 0 0 0 550 451 400 400 5697 6489 55847 34200 Mix4_TiO2_1_3 4148 55847 34200 Mix4_TiO2_1_3 4148 P27448;P27448-5;P27448-2;P27448-4;P27448-3 P27448 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.431095 0 0.431095 0 1.03353E-39 231.92 0 0 1 S LDASDSSSSSNLS CK1 0.081 1.03353E-39 231.92 _SSELDASDSpSSSSNLSLAK_ SSELDASDS(0.082)S(0.431)S(0.431)S(0.055)S(0.001)NLSLAK S(-142.4)S(-141.18)ELDAS(-48.74)DS(-7.2)S(0)S(0)S(-8.94)S(-28.74)NLS(-88.84)LAK 10 2 982.92025 0.44504 0 0 0 0 0 0 0 0 0 551 451 401 401 5697 6489 55847 34200 Mix4_TiO2_1_3 4148 55847 34200 Mix4_TiO2_1_3 4148 P27448;P27448-5;P27448-2;P27448-4;P27448-3 P27448 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.431095 0 0.431095 0 1.03353E-39 231.92 0 0 1 S DASDSSSSSNLSL CK1 0.143 1.03353E-39 231.92 _SSELDASDSpSSSSNLSLAK_ SSELDASDS(0.082)S(0.431)S(0.431)S(0.055)S(0.001)NLSLAK S(-142.4)S(-141.18)ELDAS(-48.74)DS(-7.2)S(0)S(0)S(-8.94)S(-28.74)NLS(-88.84)LAK 11 2 982.92025 0.44504 0 0 0 0 0 0 0 0 0 552 451 413 413 6579 7529;7530 66684 40916 Mix4_TiO2_Reinj_1_3 2570 66682 40914 Mix4_TiO2_Reinj_1_3 2294 P27448;P27448-5;P27448-2;P27448-4;P27448-3 P27448 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.887499 8.97633 0.111356 -6.97246 1.09762 13.409 0 0 0.887499 8.97633 1.28702E-25 177.02 0.184254 -6.46092 0.00104455 86.172 0.739903 4.71983 0.0763441 53.004 1 S LAKVRPSSDLNNS PKA 0.042 1.28702E-25 177.02 _VRPpSSDLNNSTGQSPHHK_ VRPS(0.887)S(0.112)DLNNSTGQSPHHK VRPS(8.98)S(-8.98)DLNNS(-37.44)T(-61.47)GQS(-92.46)PHHK 4 3 680.97975 -0.42536 254810 0 0 0 194610 0 0 60198 553 451 414 414 6579 7529;7530 66674 40902 Mix4_InSol_TiO2_1 3018 66682 40914 Mix4_TiO2_Reinj_1_3 2294 P27448;P27448-5;P27448-2;P27448-4;P27448-3 P27448 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.815659 6.46092 0.111356 -6.97246 1.09762 13.409 0 0 0.11234 -8.97633 1.28702E-25 177.02 0.815659 6.46092 0.00104455 86.172 0.24957 -4.71983 0.0763441 53.004 1 S AKVRPSSDLNNST CAMK2 0.042 1.28702E-25 177.02 _VRPSpSDLNNSTGQSPHHK_ VRPS(0.184)S(0.816)DLNNSTGQSPHHK VRPS(-6.46)S(6.46)DLNNS(-39.76)T(-62.19)GQS(-63.44)PHHK 5 3 680.97975 -0.11543 62097 0 0 0 0 0 62097 0 554 451 419 419 6579 7529;7530 66672 40899 Mix4_InSol_TiO2_1 2670 66682 40914 Mix4_TiO2_Reinj_1_3 2294 P27448;P27448-5;P27448-2;P27448-4;P27448-3 P27448 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.965727 14.5343 0.574297 2.20422 1.09762 13.409 0 0 0.974582 17.2779 0.00894826 73.05 0.965727 14.5343 0.00104455 86.172 0.478073 2.13885 0.0763441 53.004 1 S SSDLNNSTGQSPH GSK3;NEK6 0.076 1.28702E-25 177.02 _VRPSSDLNNpSTGQSPHHK_ VRPSSDLNNS(0.966)T(0.034)GQSPHHK VRPS(-39.93)S(-39.93)DLNNS(14.53)T(-14.53)GQS(-40.76)PHHK 10 3 680.97975 0.25172 493520 16786 0 0 0 0 476740 0 555 451 423 423 6579 7529;7530 66685 40918 Mix4_TiO2_Reinj_1_4 2324 66682 40914 Mix4_TiO2_Reinj_1_3 2294 P27448;P27448-5;P27448-2;P27448-4;P27448-3 P27448 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.999974 45.9729 0.554575 6.97246 1.09762 13.409 0 0 0.999974 45.9729 1.28702E-25 177.02 0.574021 7.316 0.00104455 86.172 0.988979 20.6023 0.0763441 53.004 1 S NNSTGQSPHHKVQ CK1;Proline-directed 0.05 1.28702E-25 177.02 _VRPSSDLNNSTGQpSPHHK_ VRPSSDLNNSTGQS(1)PHHK VRPS(-107.06)S(-107.06)DLNNS(-59.65)T(-45.97)GQS(45.97)PHHK 14 3 680.97975 1.0173 3924000 53006 0 0 3554300 0 32320 284440 556 452 403 403 3220;5700 3652;6493 55868 34208 Mix4_InSol_Tio2_Reinj_1 3165 30519 18964 Mix4_TiO2_Reinj_1_3 2432 P27448-7;P27448-6 P27448-7 P27448-7 >sp|P27448-7|MARK3_HUMAN Isoform 7 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-6|MARK3_HUMAN Isoform p58 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 0.374535 0.516138 0 0 0.0654436 -9.67563 1.1575E-11 133.48 0.00259975 -25.7191 0.316335 38.785 0.374535 0.516138 1.48554 12.496 1 S SSDLNNSTGQSPH GSK3;NEK6 0.076 1.1575E-11 133.48 _SSEVRPSSDLNNpSTGQSPHHK_ S(0.021)S(0.021)EVRPS(0.021)S(0.021)DLNNS(0.375)T(0.333)GQS(0.209)PHHK S(-12.5)S(-12.5)EVRPS(-12.5)S(-12.5)DLNNS(0.52)T(-0.52)GQS(-2.54)PHHK 13 3 782.0153 0.38581 0 0 0 0 0 0 0 0 557 452 407 407 3220;5700 3652;6493 55869 34209 Mix4_TiO2_Reinj_1_3 2682 30519 18964 Mix4_TiO2_Reinj_1_3 2432 P27448-7;P27448-6 P27448-7 P27448-7 >sp|P27448-7|MARK3_HUMAN Isoform 7 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-6|MARK3_HUMAN Isoform p58 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 0.997248 25.7529 0 0 0.997248 25.7529 1.1575E-11 133.48 0.970147 15.5968 0.316335 38.785 0.208576 -2.54229 1.48554 12.496 1 S NNSTGQSPHHKVQ CK1;Proline-directed 0.05 1.1575E-11 133.48 _SSEVRPSSDLNNSTGQpSPHHK_ SSEVRPSSDLNNST(0.003)GQS(0.997)PHHK S(-101.4)S(-101.4)EVRPS(-101.4)S(-90.03)DLNNS(-39.95)T(-25.75)GQS(25.75)PHHK 17 3 782.0153 -0.47936 1241000 0 0 0 1124300 0 116680 0 558 455 11 11 5137 5847 49701 30365 Mix4_TiO2_1_6 2496 49701 30365 Mix4_TiO2_1_6 2496 P27707 P27707 P27707 >sp|P27707|DCK_HUMAN Deoxycytidine kinase OS=Homo sapiens GN=DCK PE=1 SV=1 0.915951 10.5161 0.915951 10.5161 0.000816149 97.847 0 0 0.046472 -9.90128 0.00555828 78.536 0.0133796 -18.5916 0.00294072 87.901 4.25542E-05 -42.5653 0.00617302 77.805 1 S PKRSCPSFSASSE CK1;GSK3 0.081 0.000816149 97.847 _SCPpSFSASSEGTR_ SCPS(0.916)FS(0.081)AS(0.003)SEGTR S(-70.32)CPS(10.52)FS(-10.52)AS(-25.29)S(-50.4)EGT(-67.24)R 4 2 726.77669 -0.15174 61144 2.321 61144 0 0 0 0 0 0 559 455 15 15 5137 5847 49698 30356 Mix4_InSol_TiO2_1 4053 49701 30365 Mix4_TiO2_1_6 2496 P27707 P27707 P27707 >sp|P27707|DCK_HUMAN Deoxycytidine kinase OS=Homo sapiens GN=DCK PE=1 SV=1 0.967404 18.5916 0.859685 8.29106 0.000816149 97.847 0 0 0.465918 0 0.00555828 78.536 0.967404 18.5916 0.00294072 87.901 0.00120416 -28.0479 0.00617302 77.805 1 S CPSFSASSEGTRI CK1 0.143 0.000816149 97.847 _SCPSFSApSSEGTR_ SCPS(0.013)FS(0.01)AS(0.967)S(0.01)EGTR S(-82.89)CPS(-18.59)FS(-20.08)AS(18.59)S(-20.08)EGT(-36.59)R 8 2 726.77669 -0.095044 127110 4.8249 52454 0 0 0 0 74654 0 560 455 16 16 5137 5847 49699 30358 Mix4_InSol_Tio2_Reinj_1 3881 49701 30365 Mix4_TiO2_1_6 2496 P27707 P27707 P27707 >sp|P27707|DCK_HUMAN Deoxycytidine kinase OS=Homo sapiens GN=DCK PE=1 SV=1 0.768189 5.24951 0.127419 -8.29106 0.000816149 97.847 0 0 0.465918 0 0.00555828 78.536 0.00950228 -20.0778 0.00294072 87.901 0.768189 5.24951 0.00617302 77.805 1 S PSFSASSEGTRIK CK1 0.081 0.000816149 97.847 _SCPSFSASpSEGTR_ SCPSFS(0.001)AS(0.001)S(0.768)EGT(0.229)R S(-77.81)CPS(-42.57)FS(-28.05)AS(-28.05)S(5.25)EGT(-5.25)R 9 2 726.77669 0.21195 71062 2.6975 0 0 0 0 0 0 71062 561 455 74 74 6671 7637;7638 67634 41511 Mix4_InSol_TiO2_1 7901 67642 41521 Mix4_TiO2_Reinj_1_6 6293 P27707 P27707 P27707 >sp|P27707|DCK_HUMAN Deoxycytidine kinase OS=Homo sapiens GN=DCK PE=1 SV=1 0.999995 53.1594 0.999931 41.6373 2.51622E-32 212.32 0.999993 51.3233 7.84121E-48 235.68 0.999995 53.1594 8.82464E-39 217.94 0.999963 44.2774 5.49578E-26 181.6 1 S FEELTMSQKNGGN NEK6 0.076 7.84121E-48 235.68 _WCNVQSTQDEFEELTMpSQK_ WCNVQSTQDEFEELTMS(1)QK WCNVQS(-210.1)T(-199.93)QDEFEELT(-53.16)MS(53.16)QK 17 2 1220.4953 -0.18916 3845700 8.3907 894130 0 0 1599300 0 738390 613860 562 456 1859 1859 480;481;2786;2787 544;545;3176;3177 26752 16747 Mix4_TiO2_Reinj_1_5 3541 26709 16723 Mix4_TiO2_Reinj_1_1 3281 P27708 P27708 P27708 >sp|P27708|PYR1_HUMAN CAD protein OS=Homo sapiens GN=CAD PE=1 SV=3 1 93.9406 1 27.6068 0.0108351 71.723 1 16.2256 0.941882 16.226 1 93.9406 7.23693E-05 103.3 0 0 1 24.3882 0.00168456 82.763 1 5.27774 0.0230722 61.503 1 S PRIHRASDPGLPA PKA 0.042 7.23693E-05 103.3 _IHRApSDPGLPAEEPKEK_ IHRAS(1)DPGLPAEEPKEK IHRAS(93.94)DPGLPAEEPKEK 5 3 651.98584 -0.19065 20355000 1216700 104900 0 15212000 0 2061500 1759400 563 457 660 660 4738 5382;5383 45185 27640 Mix4_TiO2_Reinj_1_5 2537 45185 27640 Mix4_TiO2_Reinj_1_5 2537 P27815-2;P27815;P27815-7;P27815-6;P27815-3;P27815-4 P27815-2 P27815-2 >sp|P27815-2|PDE4A_HUMAN Isoform PDE4A11 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A OS=Homo sapiens GN=PDE4A;>sp|P27815|PDE4A_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4A OS=Homo sapiens GN=PDE4A PE=1 SV=3;>sp|P27815-7|PDE4A_HUMAN Isoform 0.999987 48.7682 0.0528361 -12.2857 0.53927 12.286 0.999987 48.7682 0.0576959 48.768 2 S YSAIRQSPSPPPE PKA;Proline-directed 0.042 0.0576959 48.768 _QpSPpSPPPEEESR_ QS(1)PS(1)PPPEEESR QS(48.77)PS(48.77)PPPEEES(-48.77)R 2 2 750.27619 0.25341 59948 0 0 0 59948 0 0 0 564 457 183 183 5568 6345 54489 33358 Mix4_TiO2_1_5 3140 54489 33358 Mix4_TiO2_1_5 3140 P27815-2;P27815;P27815-7;P27815-6 P27815-2 P27815-2 >sp|P27815-2|PDE4A_HUMAN Isoform PDE4A11 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A OS=Homo sapiens GN=PDE4A;>sp|P27815|PDE4A_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4A OS=Homo sapiens GN=PDE4A PE=1 SV=3;>sp|P27815-7|PDE4A_HUMAN Isoform 0.999799 36.9644 0.999799 36.9644 0.122497 36.964 0 0 1 S VPSNKRSPLGGPT CK1;Proline-directed 0.05 0.122497 36.964 _pSPLGGPTPVCK_ S(1)PLGGPTPVCK S(36.96)PLGGPT(-36.96)PVCK 1 2 596.77523 0.26876 32796 32796 0 0 0 0 0 0 565 457 44 44 5573 6350 54511 33381 Mix4_TiO2_Reinj_1_5 7707 54511 33381 Mix4_TiO2_Reinj_1_5 7707 P27815-2 P27815-2 P27815-2 >sp|P27815-2|PDE4A_HUMAN Isoform PDE4A11 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A OS=Homo sapiens GN=PDE4A 0.999981 47.4019 0.999952 43.3317 0.00942306 73.177 0.999981 47.4019 8.91169E-06 101.23 1 S APRRPRSPPSSPV CAMK2;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 8.91169E-06 101.23 _pSPPSSPVFFASPSPTFR_ S(1)PPSSPVFFASPSPTFR S(47.4)PPS(-47.4)S(-64.25)PVFFAS(-101.23)PS(-101.23)PT(-101.23)FR 1 2 944.43748 -0.25883 138240 37287 0 0 100960 0 0 0 566 458 583 583 153 179 1679 1171 Mix4_TiO2_Reinj_1_6 3709 1668 1159 Mix4_InSol_Tio2_Reinj_1 4626 P27824 P27824 P27824 >sp|P27824|CALX_HUMAN Calnexin OS=Homo sapiens GN=CANX PE=1 SV=2 1 17.7143 1 44.2493 0.0736582 44.249 0 0 1 17.7143 0.00757322 77.615 0 0 1 0.918602 0.0549852 49.536 1 79.6027 0.00649592 79.603 1 S DEILNRSPRNRKP CDK1;NEK6;Proline-directed 0.0057 0.00649592 79.603 _AEEDEILNRpSPR_ AEEDEILNRS(1)PR AEEDEILNRS(17.71)PR 10 2 754.84068 -0.034628 16945000 4065400 0 0 12119000 0 456630 304260 567 458 554 554 4599;5150 5221;5864 43634 26757 Mix4_TiO2_Reinj_1_3 3012 49925 30521 Mix4_TiO2_Reinj_1_3 2983 P27824 P27824 P27824 >sp|P27824|CALX_HUMAN Calnexin OS=Homo sapiens GN=CANX PE=1 SV=2 0.999853 41.3469 0.996936 28.1343 0.671846 28.134 0.999853 41.3469 0.0145467 63.81 1 S LEEKQKSDAEEDG CK2 0.117 0.0145467 63.81 _QKpSDAEEDGGTVSQEEEDR_ QKS(1)DAEEDGGTVSQEEEDR QKS(41.35)DAEEDGGT(-41.35)VS(-41.35)QEEEDR 3 2 1094.9293 0.12843 203900 54549 0 0 149350 0 0 0 568 458 564 564 4599;5150 5221;5864 49925 30521 Mix4_TiO2_Reinj_1_3 2983 49925 30521 Mix4_TiO2_Reinj_1_3 2983 P27824 P27824 P27824 >sp|P27824|CALX_HUMAN Calnexin OS=Homo sapiens GN=CANX PE=1 SV=2 0.917712 10.4737 0.00153192 -28.1343 0.671846 28.134 0.917712 10.4737 0.0145467 63.81 1 S EDGGTVSQEEEDR CK2 0.117 0.0145467 63.81 _SDAEEDGGTVpSQEEEDRKPK_ SDAEEDGGT(0.082)VS(0.918)QEEEDRKPK S(-63.81)DAEEDGGT(-10.47)VS(10.47)QEEEDRKPK 11 3 762.6517 0.19143 343430 0 0 0 343430 0 0 0 569 459 16 16 2527 2872 23777 14768 Mix4_TiO2_Reinj_1_6 3455 23776 14767 Mix4_TiO2_1_6 2703 P28066 P28066 P28066 >sp|P28066|PSA5_HUMAN Proteasome subunit alpha type-5 OS=Homo sapiens GN=PSMA5 PE=1 SV=3 0.99999 50.1598 0.998264 27.5972 0.00292403 72.838 0.99999 50.1598 0.00357258 70.838 1 S RGVNTFSPEGRLF Proline-directed 0.05 0.00292403 72.838 _GVNTFpSPEGR_ GVNTFS(1)PEGR GVNT(-50.16)FS(50.16)PEGR 6 2 572.24515 0.27032 57735 15593 0 0 42142 0 0 0 570 459 56 56 2928 3332 27962 17389 Mix4_TiO2_Reinj_1_6 4230 27962 17389 Mix4_TiO2_Reinj_1_6 4230 P28066 P28066 P28066 >sp|P28066|PSA5_HUMAN Proteasome subunit alpha type-5 OS=Homo sapiens GN=PSMA5 PE=1 SV=3 0.982292 17.4969 0 0 0.982292 17.4969 0.117874 39.358 1 S VEKRITSPLMEPS CAMK2;PKA;Proline-directed 0.003024 0.117874 39.358 _ITpSPLM(ox)EPSSIEK_ IT(0.017)S(0.982)PLMEPSSIEK IT(-17.5)S(17.5)PLMEPS(-39.36)S(-39.36)IEK 3 2 764.35424 0.1201 24794 0 0 0 24794 0 0 0 571 461 737 737 5645 6431 55125 33732 Mix4_TiO2_Reinj_1_1 6687 55125 33732 Mix4_TiO2_Reinj_1_1 6687 P28290;P28290-3;P28290-2 P28290 P28290 >sp|P28290|SSFA2_HUMAN Sperm-specific antigen 2 OS=Homo sapiens GN=SSFA2 PE=1 SV=3;>sp|P28290-3|SSFA2_HUMAN Isoform 3 of Sperm-specific antigen 2 OS=Homo sapiens GN=SSFA2;>sp|P28290-2|SSFA2_HUMAN Isoform 2 of Sperm-specific antigen 2 OS=Homo sapiens GN=SSF 0.673931 3.16702 0.144263 -6.07671 0.0258608 58.904 0 0 0.673931 3.16702 0.0111871 71.848 0.582445 2.05671 0.0170815 64.847 0.606736 2.20498 0.466525 19.439 1 S GYPLRRSQSLPTT NEK6;NIMA;PKA 0.001741464 0.0111871 71.848 _pSQSLPTTLLSPVR_ S(0.674)QS(0.325)LPT(0.001)TLLSPVR S(3.17)QS(-3.17)LPT(-28.69)T(-36.95)LLS(-71.85)PVR 1 2 739.88436 0.1767 807690 0 0 0 577470 0 119230 110990 572 461 739 739 5645 6431 55124 33731 Mix4_TiO2_1_5 6283 55125 33732 Mix4_TiO2_Reinj_1_1 6687 P28290;P28290-3;P28290-2 P28290 P28290 >sp|P28290|SSFA2_HUMAN Sperm-specific antigen 2 OS=Homo sapiens GN=SSFA2 PE=1 SV=3;>sp|P28290-3|SSFA2_HUMAN Isoform 3 of Sperm-specific antigen 2 OS=Homo sapiens GN=SSFA2;>sp|P28290-2|SSFA2_HUMAN Isoform 2 of Sperm-specific antigen 2 OS=Homo sapiens GN=SSF 0.584554 3.70811 0.584554 3.70811 0.0258608 58.904 0 0 0.354512 -2.58801 0.0111871 71.848 0.362731 -2.05671 0.0170815 64.847 0.365175 -2.20498 0.466525 19.439 1 S PLRRSQSLPTTLL 14-3-3 binding;CAMK2;CHK1;CHK1/2;PKD 0.0001701 0.0111871 71.848 _SQpSLPTTLLSPVR_ S(0.144)QS(0.585)LPT(0.249)T(0.022)LLSPVR S(-6.08)QS(3.71)LPT(-3.71)T(-14.19)LLS(-58.9)PVR 3 2 739.88436 -0.35693 66012 66012 0 0 0 0 0 0 573 461 92 92 6143 7014 60875 36893 Mix4_TiO2_1_1 4218 60876 36894 Mix4_TiO2_Reinj_1_1 4837 P28290;P28290-3 P28290 P28290 >sp|P28290|SSFA2_HUMAN Sperm-specific antigen 2 OS=Homo sapiens GN=SSFA2 PE=1 SV=3;>sp|P28290-3|SSFA2_HUMAN Isoform 3 of Sperm-specific antigen 2 OS=Homo sapiens GN=SSFA2 0.999995 53.1895 0.999995 53.1895 0.000786187 92.755 0 0 0.995715 26.4631 7.25845E-06 107.94 0 0 0 0 1 S RTPLGASLDEQSS CK2;NEK6 0.076 7.25845E-06 107.94 _TPLGApSLDEQSSSTLK_ TPLGAS(1)LDEQSSSTLK T(-53.19)PLGAS(53.19)LDEQS(-75.24)S(-81.71)S(-87.97)T(-87.97)LK 6 2 857.40076 0.79714 285040 50880 0 0 234160 0 0 0 574 465 880 880 391 447 3726 2220 Mix4_TiO2_1_5 6085 3726 2220 Mix4_TiO2_1_5 6085 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.999383 32.0915 0.999383 32.0915 5.3219E-05 113.64 0 0 0.997572 26.1371 0.011135 72.209 0.819649 6.57508 0.997394 6.5751 0 0 1 S LIRAPDSLKTLAD 5.3219E-05 113.64 _APDpSLKTLADFDPR_ APDS(0.999)LKT(0.001)LADFDPR APDS(32.09)LKT(-32.09)LADFDPR 4 2 813.38218 0.58455 436260 99284 0 0 284220 0 52749 0 575 465 570 570 469;4737 533;5380 4401 2666 Mix4_TiO2_Reinj_1_5 4893 4401 2666 Mix4_TiO2_Reinj_1_5 4893 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 1 129.311 1 74.421 0.000697221 107.29 0.992472 24.2107 0.176426 24.211 1 129.311 6.11331E-05 129.31 0 0 1 102.33 6.94551E-05 127.89 1 69.7174 0.000125169 118.34 1 S NQRARQSPEDVYF CK2;PKA;Proline-directed 0.042 6.11331E-05 129.31 _ARQpSPEDVYFSK_ ARQS(1)PEDVYFSK ARQS(129.31)PEDVY(-129.31)FS(-129.31)K 4 3 502.89233 -0.076594 6667500 7.592 2293300 0 0 2188500 0 1365300 820460 576 465 577 577 469;4737 533;5380 4400 2664 Mix4_TiO2_Reinj_1_5 4931 4401 2666 Mix4_TiO2_Reinj_1_5 4893 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.865766 8.09751 0.00336779 -24.6972 0.000697221 107.29 0.0153179 -18.0129 0.176426 24.211 0.865766 8.09751 6.11331E-05 129.31 0 0 0.270075 -2.31133 6.94551E-05 127.89 0.152499 -6.5872 0.000125169 118.34 1 S PEDVYFSKSEQLK CK2 0.117 6.11331E-05 129.31 _ARQSPEDVYFpSK_ ARQS(0.134)PEDVYFS(0.866)K ARQS(-8.1)PEDVY(-41.18)FS(8.1)K 11 2 753.83486 0.014255 6313600 7.1889 0 0 0 6313600 0 0 0 577 465 373 373 1444;6697 1622;7668 67926 41703 Mix4_TiO2_Reinj_1_5 7131 13498 8275 Mix4_TiO2_Reinj_1_5 7041 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.999999 61.1392 0.999979 46.7663 5.44684E-18 141.08 0.999999 61.1392 4.23673E-18 144.57 0 0 0.986887 19.5593 0.00221228 81.835 0.995632 29.7504 0.230736 64.087 1 S EQCWPESGECGPC 4.23673E-18 144.57 _WTPPQDSGGREDIVYSVTCEQCWPEpSGECGPCEASVR_ WTPPQDSGGREDIVYSVTCEQCWPES(1)GECGPCEASVR WT(-97.84)PPQDS(-92.93)GGREDIVY(-86.96)S(-82.93)VT(-74.17)CEQCWPES(61.14)GECGPCEAS(-61.14)VR 26 4 1092.1959 -0.76591 3830900 0.081526 160570 0 0 3087400 0 211390 371570 578 465 869 869 1943 2198 17801 10645 Mix4_TiO2_Reinj_1_5 8710 17801 10645 Mix4_TiO2_Reinj_1_5 8710 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 1 92.4932 0 0 1 92.4932 0.00144293 92.493 1 S KFADIVSILDKLI CK2 0.117 0.00144293 92.493 _FADIVpSILDK_ FADIVS(1)ILDK FADIVS(92.49)ILDK 6 2 600.79923 -0.28626 31709 0.19437 0 0 0 31709 0 0 0 579 465 961 961 2706 3082 25545 15783 Mix4_TiO2_1_5 6048 25546 15784 Mix4_TiO2_Reinj_1_5 6984 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.515693 0.272706 0.515693 0.272706 0.407399 19.396 0.000412373 -33.8453 0.00333986 72.82 1 S QKRIAYSLLGLKD 0.00333986 72.82 _IAYpSLLGLK_ IAY(0.484)S(0.516)LLGLK IAY(-0.27)S(0.27)LLGLK 4 2 529.2883 -0.92818 14754 2.36 14754 0 0 0 0 0 0 580 465 153 153 2728 3109 25775 15930 Mix4_TiO2_Reinj_2_1 4590 25773 15927 Mix4_TiO2_Reinj_1_5 7077 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.913938 12.8171 0.617273 2.16809 0.000283464 95.453 0.415211 -0.931459 8.94037E-26 182.6 0.913938 12.8171 0.081056 52.358 0 0 0 0 1 S PDEITVSSDFEAR 8.94037E-26 182.6 _IDTIAPDEITVpSSDFEAR_ IDTIAPDEIT(0.038)VS(0.914)S(0.048)DFEAR IDT(-52.36)IAPDEIT(-13.78)VS(12.82)S(-12.82)DFEAR 12 2 1029.967 -0.65299 41159 0.061808 32381 0 0 0 8777.8 0 0 581 465 154 154 2728 3109 25773 15927 Mix4_TiO2_Reinj_1_5 7077 25773 15927 Mix4_TiO2_Reinj_1_5 7077 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.944103 12.7862 0.374687 -2.16809 0.000283464 95.453 0.944103 12.7862 8.94037E-26 182.6 0.0477753 -12.8171 0.081056 52.358 0 0 0 0 1 S DEITVSSDFEARH CK2 0.117 8.94037E-26 182.6 _IDTIAPDEITVSpSDFEAR_ IDTIAPDEIT(0.006)VS(0.05)S(0.944)DFEAR IDT(-159.49)IAPDEIT(-21.83)VS(-12.79)S(12.79)DFEAR 13 2 1029.967 0.2344 562700 0.84501 0 0 0 562700 0 0 0 582 465 897 897 3637;6600 4099;4100;4101;7553;7554;7555 34193 21129 Mix4_TiO2_1_5 6335 34205 21165 Mix4_TiO2_Reinj_1_1 5141 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.814215 8.57013 0.814215 8.57013 6.56777E-08 156.45 0.980837 18.3439 0.0775713 44.853 0.996285 24.9314 0.00133544 95.416 0.822271 10.748 0.148176 37.446 0.998513 28.9212 0.000381577 95.244 0.941481 12.8217 0.0232612 59.611 1 S VSIRLPSTSGSEG CAMK2;GSK3 0.042 8.1107E-09 158.77 _LPpSTSGSEGVPFR_ LPS(0.814)T(0.113)S(0.036)GS(0.036)EGVPFR LPS(8.57)T(-8.57)S(-13.51)GS(-13.51)EGVPFR 3 2 707.32413 0.19841 23917 0.24399 23917 0 0 0 0 0 0 583 465 899 899 3637;6600 4099;4100;4101;7553;7554;7555 66893 41041 Mix4_InSol_Tio2_Reinj_1 7507 34205 21165 Mix4_TiO2_Reinj_1_1 5141 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.975757 18.1503 0.633385 3.5822 5.25124E-06 138.4 0.53366 1.04292 0.0775713 44.853 0.896472 10.0457 8.1107E-09 158.77 0.822271 10.748 0.148176 37.446 0.847583 8.25711 4.9386E-05 118.83 0.975757 18.1503 3.95509E-05 122.99 1 S IRLPSTSGSEGVP CK2 0.117 8.1107E-09 158.77 _VSIRLPSTpSGSEGVPFR_ VSIRLPS(0.002)T(0.007)S(0.976)GS(0.015)EGVPFR VS(-51.86)IRLPS(-27.07)T(-21.21)S(18.15)GS(-18.15)EGVPFR 9 2 934.96694 -0.096193 10575000 107.88 0 0 0 4167400 0 811450 5595900 584 465 901 901 3637;6600 4099;4100;4101;7553;7554;7555 66891 41037 Mix4_InSol_Tio2_Reinj_1 7539 34205 21165 Mix4_TiO2_Reinj_1_1 5141 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.99991 40.7142 0.999451 32.6434 6.56777E-08 156.45 0.993863 22.8645 1.86022E-05 131.85 0.998937 29.8791 8.1107E-09 158.77 0.982067 17.7497 3.39935E-05 125.34 0.963116 15.0531 4.9386E-05 118.83 0.99991 40.7142 3.95509E-05 122.99 1 S LPSTSGSEGVPFR CK1 0.143 8.1107E-09 158.77 _VSIRLPSTSGpSEGVPFR_ VSIRLPSTSGS(1)EGVPFR VS(-58.68)IRLPS(-58.68)T(-56.9)S(-40.71)GS(40.71)EGVPFR 11 3 623.64705 -0.51035 89016000 908.11 15891000 1584400 0 61054000 182710 6968500 3334900 585 465 892 892 6054;6600 6905;7553;7554;7555 59764 36261 Mix4_TiO2_Reinj_1_5 6632 66898 41052 Mix4_TiO2_1_5 6260 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 1 102.602 1 97.4645 7.26197E-07 116.75 0.999956 43.5366 0.0761753 43.537 1 102.602 6.6364E-06 105.52 0.251653 -6.19264 0.000381577 95.244 0.327208 -3.24758 0.0544528 55.906 1 S DFDPRVSIRLPST AURORA;AURORA-1;PKA 0.020748 7.26197E-07 116.75 _TLADFDPRVpSIR_ TLADFDPRVS(1)IR T(-102.6)LADFDPRVS(102.6)IR 10 2 735.36105 -0.025692 3859200 588600 82926 0 3187700 0 0 0 586 465 910 910 6293 7190 62953 38347 Mix4_TiO2_Reinj_1_5 8658 62953 38347 Mix4_TiO2_Reinj_1_5 8658 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.999961 44.0657 0.999443 34.3813 0.00446437 113.75 0.999278 31.4144 0.00219818 75.077 0.999961 44.0657 0.00313356 126.38 1 S VPFRTVSEWLESI CAMK2 0.042 0.00313356 126.38 _TVpSEWLESIK_ TVS(1)EWLESIK T(-44.07)VS(44.07)EWLES(-124.5)IK 3 2 636.29959 -0.19145 1506900 9.3749 346430 79097 0 1081300 0 0 0 587 465 775 775 6467;6468 7397;7399 65326 40068 Mix4_TiO2_Reinj_1_5 4541 65319 40056 Mix4_TiO2_1_4 3218 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.999765 36.3415 5.10654E-05 -42.8375 2.4347E-54 269.2 2.39829E-06 -55.661 1.08721E-15 157.36 0.999765 36.3415 1.75089E-20 191.59 0.00454708 -22.494 0.0147885 69.135 0.325319 0 2.39891E-16 150.77 0.255064 0 2.88773E-16 149.56 1 S EATYTTSGGKIPI CK1 0.143 2.4347E-54 269.2 _VLEDDPEATYTTpSGGK_ VLEDDPEATYTTS(1)GGK VLEDDPEAT(-116.06)Y(-98.09)T(-55.65)T(-36.34)S(36.34)GGK 13 2 881.87458 0.33996 956420 0.35614 0 0 0 956420 0 0 0 588 465;466;665 761;768;762 761 6587 7539 66779 40951 Mix4_TiO2_Reinj_1_5 5421 66779 40951 Mix4_TiO2_Reinj_1_5 5421 P29317;P54762;Q9UF33;Q15375;Q15375-2;Q9UF33-2;P54756;P54756-2;P29322;P29320;P54756-3;Q06187;P29323;P29323-3;P29323-2;P54760;P54753 P29317;P29323;P54760 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2;>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens GN=EPHB1 PE=1 SV=1;>sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens GN=EPHA6 PE=2 SV=2;>sp|Q15 0.999986 48.5729 0 0 0.999986 48.5729 0.0976655 48.573 1 S VSDFGLSRFLEDD;VSDFGLSRFLEEN;VSDFGLSRVLEDD 0.0976655 48.573 _VSDFGLpSR_ VSDFGLS(1)R VS(-48.57)DFGLS(48.57)R 7 2 480.71296 -0.25732 43091 0.3101 0 0 0 43091 0 0 0 589 465 790 790 6694 7664 67909 41695 Mix4_TiO2_1_5 5188 67909 41695 Mix4_TiO2_1_5 5188 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.982053 17.3826 0.982053 17.3826 0.0300366 52.611 0 0 1 S TAPEAISYRKFTS 0.0300366 52.611 _WTAPEAIpSYR_ WTAPEAIS(0.982)Y(0.018)R WT(-52.61)APEAIS(17.38)Y(-17.38)R 8 2 637.28428 -0.5456 22417 22417 0 0 0 0 0 0 590 466 776 776 2005;2006 2270;2272 18360 11137 Mix4_InSol_TiO2_1 6655 18375 11159 Mix4_TiO2_Reinj_1_5 6313 P29323;P29323-3;P29323-2 P29323 P29323 >sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 PE=1 SV=5;>sp|P29323-3|EPHB2_HUMAN Isoform 3 of Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2;>sp|P29323-2|EPHB2_HUMAN Isoform Short of Ephrin type-B receptor 2 OS=Homo sapiens GN 0.999039 33.4212 0.981758 17.8893 5.25254E-10 126.05 0.874589 8.56539 3.05227E-06 109.55 0.994685 25.0428 4.96298E-10 126.68 0 0 0.999039 33.4212 7.66907E-10 120.84 0.993576 22.5261 0.00155038 79.98 1 S FLEDDTSDPTYTS 4.96298E-10 126.68 _FLEDDTpSDPTYTSALGGK_ FLEDDTS(0.999)DPTYTSALGGK FLEDDT(-33.42)S(33.42)DPT(-33.42)Y(-42.88)T(-63.15)S(-72.17)ALGGK 7 2 998.9248 0.14833 11433000 29.922 4500600 118060 0 4539000 0 1437400 838270 591 468 38 38 4736 5379 45148 27627 Mix4_InSol_Tio2_Reinj_1 6854 45147 27626 Mix4_InSol_TiO2_1 6860 P29558;P29558-2 P29558 P29558 >sp|P29558|RBMS1_HUMAN RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 PE=1 SV=3;>sp|P29558-2|RBMS1_HUMAN Isoform 2 of RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 0.232518 0 0.177805 0 0.000562166 92.271 0.232518 0 0.00330012 79.412 1 S HPMAPPSPSTTSS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000562166 92.271 _QSLVPAHPMAPPpSPSTTSSNNNSSSSSNSGWDQLSK_ QSLVPAHPMAPPS(0.233)PS(0.233)T(0.233)T(0.233)S(0.059)S(0.004)NNNS(0.004)S(0.001)SSSNSGWDQLSK QS(-40.11)LVPAHPMAPPS(0)PS(0)T(0)T(0)S(-5.94)S(-17.35)NNNS(-17.35)S(-22.79)S(-28.05)S(-28.05)S(-33.12)NS(-32.73)GWDQLS(-51.45)K 13 3 1255.5547 -0.061254 0 0 0 0 0 0 0 0 592 468 40 40 4736 5379 45148 27627 Mix4_InSol_Tio2_Reinj_1 6854 45147 27626 Mix4_InSol_TiO2_1 6860 P29558;P29558-2 P29558 P29558 >sp|P29558|RBMS1_HUMAN RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 PE=1 SV=3;>sp|P29558-2|RBMS1_HUMAN Isoform 2 of RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 0.232518 0 0.177805 0 0.000562166 92.271 0.232518 0 0.00330012 79.412 1 S MAPPSPSTTSSNN GSK3 0.081 0.000562166 92.271 _QSLVPAHPMAPPpSPSTTSSNNNSSSSSNSGWDQLSK_ QSLVPAHPMAPPS(0.233)PS(0.233)T(0.233)T(0.233)S(0.059)S(0.004)NNNS(0.004)S(0.001)SSSNSGWDQLSK QS(-40.11)LVPAHPMAPPS(0)PS(0)T(0)T(0)S(-5.94)S(-17.35)NNNS(-17.35)S(-22.79)S(-28.05)S(-28.05)S(-33.12)NS(-32.73)GWDQLS(-51.45)K 15 3 1255.5547 -0.061254 0 0 0 0 0 0 0 0 593 468 43 43 4736 5379 45147 27626 Mix4_InSol_TiO2_1 6860 45147 27626 Mix4_InSol_TiO2_1 6860 P29558;P29558-2 P29558 P29558 >sp|P29558|RBMS1_HUMAN RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 PE=1 SV=3;>sp|P29558-2|RBMS1_HUMAN Isoform 2 of RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 0.177805 0 0.177805 0 0.000562166 92.271 0.0591573 -5.94447 0.00330012 79.412 1 S PSPSTTSSNNNSS CK1 0.081 0.000562166 92.271 _QSLVPAHPMAPPpSPSTTSSNNNSSSSSNSGWDQLSK_ QSLVPAHPMAPPS(0.178)PS(0.178)T(0.178)T(0.178)S(0.178)S(0.047)NNNS(0.047)S(0.013)S(0.004)S(0.001)SNSGWDQLSK QS(-44.37)LVPAHPMAPPS(0)PS(0)T(0)T(0)S(0)S(-5.79)NNNS(-5.79)S(-11.46)S(-17)S(-22.96)S(-33.78)NS(-36.73)GWDQLS(-64.57)K 18 3 1255.5547 -0.00075511 0 0 0 0 0 0 0 0 594 469 403 403 2972 3380 28301 17579 Mix4_TiO2_Reinj_1_5 1967 28301 17579 Mix4_TiO2_Reinj_1_5 1967 P29590-2;P29590;P29590-7;P29590-3;P29590-5;P29590-4 P29590-2 P29590-2 >sp|P29590-2|PML_HUMAN Isoform PML-2 of Probable transcription factor PML OS=Homo sapiens GN=PML;>sp|P29590|PML_HUMAN Probable transcription factor PML OS=Homo sapiens GN=PML PE=1 SV=3;>sp|P29590-7|PML_HUMAN Isoform PML-5 of Probable transcription factor P 0.999923 44.1333 0 0 0.999923 44.1333 0.0651798 44.133 1 S AVSKKASPEAAST CHK1;CK1;PKD;Proline-directed 0.020748 0.0651798 44.133 _KApSPEAASTPR_ KAS(1)PEAASTPR KAS(44.13)PEAAS(-44.13)T(-44.13)PR 3 2 597.77936 0.57022 125020 0 0 0 125020 0 0 0 595 469 504 504 3307;5722 3743;6520 31195 19327 Mix4_InSol_Tio2_Reinj_1 2567 56183 34352 Mix4_TiO2_Reinj_1_5 1910 P29590-2;P29590;P29590-7;P29590-3;P29590-5;P29590-4;P29590-6 P29590-2 P29590-2 >sp|P29590-2|PML_HUMAN Isoform PML-2 of Probable transcription factor PML OS=Homo sapiens GN=PML;>sp|P29590|PML_HUMAN Probable transcription factor PML OS=Homo sapiens GN=PML PE=1 SV=3;>sp|P29590-7|PML_HUMAN Isoform PML-5 of Probable transcription factor P 0.796623 9.11114 0.40053 -0.890235 0.560549 11.361 0.433929 -1.15314 0.100496 39.721 0.459822 1.07144 0.677183 19.674 0.796623 9.11114 0.471667 27.197 1 S EARLARSSPEQPR CK2;NEK6 0.076 0.100496 39.721 _LARpSSPEQPRPSTSK_ LARS(0.797)S(0.098)PEQPRPS(0.035)T(0.035)S(0.035)K LARS(9.11)S(-9.11)PEQPRPS(-13.55)T(-13.55)S(-13.55)K 4 3 574.28411 0.35983 304700 0 0 0 0 0 0 304700 596 469 505 505 3307;5722 3743;6520 31196 19328 Mix4_InSol_Tio2_Reinj_1 2570 56183 34352 Mix4_TiO2_Reinj_1_5 1910 P29590-2;P29590;P29590-7;P29590-3;P29590-5;P29590-4;P29590-6 P29590-2 P29590-2 >sp|P29590-2|PML_HUMAN Isoform PML-2 of Probable transcription factor PML OS=Homo sapiens GN=PML;>sp|P29590|PML_HUMAN Probable transcription factor PML OS=Homo sapiens GN=PML PE=1 SV=3;>sp|P29590-7|PML_HUMAN Isoform PML-5 of Probable transcription factor P 0.915152 10.9121 0.491653 0.890235 0.560549 11.361 0.56589 1.15314 0.100496 39.721 0.359291 -1.07144 0.677183 19.674 0.915152 10.9121 0.471667 27.197 1 S ARLARSSPEQPRP PKA;Polo box;Proline-directed 0.00405 0.100496 39.721 _LARSpSPEQPRPSTSK_ LARS(0.074)S(0.915)PEQPRPS(0.004)T(0.004)S(0.004)K LARS(-10.91)S(10.91)PEQPRPS(-24.11)T(-24.11)S(-24.11)K 5 2 860.92253 0.43536 690410 0 0 0 500240 0 0 190170 597 469 583 583 6130 6997 60533 36592 Mix4_TiO2_Reinj_1_3 3310 60533 36592 Mix4_TiO2_Reinj_1_3 3310 P29590-2 P29590-2 P29590-2 >sp|P29590-2|PML_HUMAN Isoform PML-2 of Probable transcription factor PML OS=Homo sapiens GN=PML 0.999974 45.855 0 0 0.999974 45.855 0.115339 45.855 0 0 0 0 1 S QPRTPASPHFRSQ ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.115339 45.855 _TPApSPHFR_ TPAS(1)PHFR T(-45.85)PAS(45.85)PHFR 4 2 496.72112 -0.29297 66587 0 0 0 66587 0 0 0 598 471 499 499 554 633;634 5245 3190 Mix4_InSol_TiO2_1 3548 5260 3195 Mix4_TiO2_Reinj_1_4 2404 P29692-2;P29692 P29692-2 P29692-2 >sp|P29692-2|EF1D_HUMAN Isoform 2 of Elongation factor 1-delta OS=Homo sapiens GN=EEF1D;>sp|P29692|EF1D_HUMAN Elongation factor 1-delta OS=Homo sapiens GN=EEF1D PE=1 SV=5 0.999981 47.548 0.931191 11.4658 0.332567 25.952 0 0 0.998986 29.9342 0.0082228 75.37 0.999981 47.548 0.0268521 58.635 0.999952 43.3971 0.0356592 56.242 1 S PQTQHVSPMRQVE CDK1;CDK2;CK1;Proline-directed 0.0057 0.0082228 75.37 _ATAPQTQHVpSPMR_ ATAPQTQHVS(1)PMR AT(-58.63)APQT(-47.55)QHVS(47.55)PMR 10 2 752.34233 1.437 666370 55416 0 0 406510 0 92217 112230 599 471 528 528 3142 3567 29830 18572 Mix4_TiO2_Reinj_1_4 6740 29828 18570 Mix4_TiO2_Reinj_1_2 5891 P29692-2;P29692 P29692-2 P29692-2 >sp|P29692-2|EF1D_HUMAN Isoform 2 of Elongation factor 1-delta OS=Homo sapiens GN=EEF1D;>sp|P29692|EF1D_HUMAN Elongation factor 1-delta OS=Homo sapiens GN=EEF1D PE=1 SV=5 1 93.6349 0 0 1 93.6349 2.98278E-19 146.57 1 S DIDLFGSDNEEED CK2;NEK6 0.076 2.98278E-19 146.57 _KPATPAEDDEDDDIDLFGpSDNEEEDKEAAQLR_ KPATPAEDDEDDDIDLFGS(1)DNEEEDKEAAQLR KPAT(-93.63)PAEDDEDDDIDLFGS(93.63)DNEEEDKEAAQLR 19 3 1219.846 1.2169 5799200 0 0 0 5799200 0 0 0 600 472 147 147 149;150 174;175 1650 1149 Mix4_TiO2_Reinj_1_3 2183 1643 1147 Mix4_TiO2_Reinj_1_3 2466 P29966 P29966 P29966 >sp|P29966|MARCS_HUMAN Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens GN=MARCKS PE=1 SV=4 0.841848 10.2435 0.584868 2.49605 0.0856383 49.308 0.841848 10.2435 0.00106066 92.248 0 0 0 0 1 S GATPSPSNETPKK CK1 0.143 0.00106066 92.248 _AEDGATPSPpSNETPKK_ AEDGATPS(0.08)PS(0.842)NET(0.079)PKK AEDGAT(-58.91)PS(-10.24)PS(10.24)NET(-10.3)PKK 10 2 854.87491 0.055005 306730 83468 0 0 223260 0 0 0 601 472 170 170 3720 4194 35108 21739 Mix4_TiO2_Reinj_1_3 5666 35108 21739 Mix4_TiO2_Reinj_1_3 5666 P29966 P29966 P29966 >sp|P29966|MARCS_HUMAN Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens GN=MARCKS PE=1 SV=4 0.999996 53.7902 0 0 0.999996 53.7902 0.0637401 53.79 0.957083 13.4832 0.807091 13.483 0.973007 15.5686 0.724709 15.569 1 S FKLSGFSFKKNKK CK1 0.081 0.0637401 53.79 _LSGFpSFKK_ LSGFS(1)FKK LS(-53.79)GFS(53.79)FKK 5 2 497.24389 -0.036146 330660 0 0 0 73505 0 152530 104620 602 474 38 38 2774 3163 26533 16590 Mix4_TiO2_Reinj_1_6 5267 26533 16590 Mix4_TiO2_Reinj_1_6 5267 P30050 P30050 P30050 >sp|P30050|RL12_HUMAN 60S ribosomal protein L12 OS=Homo sapiens GN=RPL12 PE=1 SV=1 1 75.0478 1 47.6897 0.0479918 47.69 1 43.8061 0.0602561 43.806 1 75.0478 0.00244859 75.048 1 33.3628 0.175663 33.363 0 0 1 S IGPLGLSPKKVGD CDK1;CDK2;NEK6;Proline-directed 0.0057 0.00244859 75.048 _IGPLGLpSPK_ IGPLGLS(1)PK IGPLGLS(75.05)PK 7 2 481.25954 -0.17867 134570 21966 21327 0 74535 0 16744 0 603 476 282 282 2472 2807 23210 14475 Mix4_TiO2_1_2 4807 23210 14475 Mix4_TiO2_1_2 4807 P30281 P30281 P30281 >sp|P30281|CCND3_HUMAN G1/S-specific cyclin-D3 OS=Homo sapiens GN=CCND3 PE=1 SV=2 0.514561 0.544566 0.514561 0.544566 3.72979E-07 110.74 0 0 0 0 0 0 1 S QGPSQTSTPTDVT CK1 0.081 3.72979E-07 110.74 _GSSSQGPSQTpSTPTDVTAIHL_ GSSSQGPSQT(0.016)S(0.515)T(0.454)PT(0.016)DVTAIHL GS(-59.66)S(-59.66)S(-59.66)QGPS(-43.43)QT(-15.16)S(0.54)T(-0.54)PT(-15.13)DVT(-75.74)AIHL 11 2 1075.9837 -0.15237 44169 44169 0 0 0 0 0 0 604 477 150 150 664 764 6385 3787 Mix4_TiO2_Reinj_1_3 1688 6383 3784 Mix4_TiO2_1_3 1133 P30291 P30291 P30291 >sp|P30291|WEE1_HUMAN Wee1-like protein kinase OS=Homo sapiens GN=WEE1 PE=1 SV=2 1 60.4605 1 13.6979 0.00138503 91.397 1 60.4605 0.00693787 60.461 0 0 0 0 1 S GGPGDASPRGCGA CDK1;Proline-directed 0.0057 0.00138503 91.397 _CGGPGDApSPR_ CGGPGDAS(1)PR CGGPGDAS(60.46)PR 8 2 527.19461 1.17 86169 30782 0 0 55387 0 0 0 605 477 139 139 5540 6313 54179 33151 Mix4_TiO2_1_3 7155 54179 33151 Mix4_TiO2_1_3 7155 P30291 P30291 P30291 >sp|P30291|WEE1_HUMAN Wee1-like protein kinase OS=Homo sapiens GN=WEE1 PE=1 SV=2 0.999999 60.5819 0.999999 60.5819 9.93752E-26 200.49 0.999929 41.499 1.11937E-25 198.71 1 S FLGSSFSPVRCGG CDK1;CDK2;CK1;Proline-directed 0.0057 9.93752E-26 200.49 _SPAAPYFLGSSFpSPVR_ SPAAPYFLGSSFS(1)PVR S(-200.49)PAAPY(-163.62)FLGS(-89.89)S(-60.58)FS(60.58)PVR 13 2 881.91364 -0.043715 3979100 920380 0 0 3058700 0 0 0 606 481 875 875 6822;6823 7806;7807 69147 42388 Mix4_InSol_TiO2_2 4001 69151 42390 Mix4_TiO2_1_5 4727 P30530;P30530-2 P30530 P30530 >sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo sapiens GN=AXL PE=1 SV=3;>sp|P30530-2|UFO_HUMAN Isoform Short of Tyrosine-protein kinase receptor UFO OS=Homo sapiens GN=AXL 0.949095 14.6112 0.0162071 -17.8282 0.0353551 61.862 0 0 0.0671753 -11.1895 1.34039 31.873 0.949095 14.6112 0.744847 21.972 0 0 1 S CPSTTPSPAQPAD CK1;Proline-directed 0.05 0.0353551 61.862 _YVLCPSTTPpSPAQPADR_ Y(0.006)VLCPS(0.006)T(0.006)T(0.033)PS(0.949)PAQPADR Y(-21.97)VLCPS(-21.97)T(-21.97)T(-14.61)PS(14.61)PAQPADR 10 2 970.43462 1.5199 5126.8 0 0 0 0 0 5126.8 0 607 481 884 884 6823 7807 69151 42390 Mix4_TiO2_1_5 4727 69151 42390 Mix4_TiO2_1_5 4727 P30530;P30530-2 P30530 P30530 >sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo sapiens GN=AXL PE=1 SV=3;>sp|P30530-2|UFO_HUMAN Isoform Short of Tyrosine-protein kinase receptor UFO OS=Homo sapiens GN=AXL 0.999895 40.8667 0.999895 40.8667 0.0353551 61.862 0 0 0.883406 11.1895 1.34039 31.873 0 0 0 0 1 S QPADRGSPAAPGQ PKA;Proline-directed 0.042 0.0353551 61.862 _YVLCPSTTPSPAQPADRGpSPAAPGQEDGA_ YVLCPSTTPSPAQPADRGS(1)PAAPGQEDGA Y(-61.86)VLCPS(-52.46)T(-52.46)T(-49.64)PS(-40.87)PAQPADRGS(40.87)PAAPGQEDGA 19 3 993.10597 1.3973 1197200 347570 0 0 849580 0 0 0 608 482 9 9 43 54 493 308 Mix4_TiO2_Reinj_1_4 3161 492 307 Mix4_TiO2_1_4 2595 P30566;P30566-2 P30566 P30566 >sp|P30566|PUR8_HUMAN Adenylosuccinate lyase OS=Homo sapiens GN=ADSL PE=1 SV=2;>sp|P30566-2|PUR8_HUMAN Isoform Delta-ADSL of Adenylosuccinate lyase OS=Homo sapiens GN=ADSL 0.999993 52.5669 0.999984 48.1734 0.0171813 64.727 0.999993 52.5669 0.0293237 57.963 1 S AGGDHGSPDSYRS Proline-directed 0.05 0.0171813 64.727 _(ac)AAGGDHGpSPDSYR_ AAGGDHGS(1)PDSYR AAGGDHGS(52.57)PDS(-52.57)Y(-57.96)R 8 2 706.26734 0.32996 257800 56631 0 0 201170 0 0 0 609 487 114 114 4819 5469 46016 28152 Mix4_TiO2_Reinj_1_4 4378 46015 28151 Mix4_TiO2_Reinj_1_4 4359 P31323 P31323 P31323 >sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens GN=PRKAR2B PE=1 SV=3 1 103.711 1 113.032 8.03899E-17 149.71 0 0 1 103.711 1.49447E-23 156.79 0.998302 27.6932 9.5925E-07 99.159 0.999999 61.511 4.68093E-11 125.91 1 S RFTRRASVCAEAY AURORA;AURORA-1;AURORA-A;CAMK2;CK1;PKA 0.002856 1.49447E-23 156.79 _RApSVCAEAYNPDEEEDDAESR_ RAS(1)VCAEAYNPDEEEDDAESR RAS(103.71)VCAEAY(-103.71)NPDEEEDDAES(-134.94)R 3 2 1246.979 0.54819 3339000 623700 0 0 1904700 0 402060 408560 610 488 20 20 6530 7473 65971 40451 Mix4_TiO2_Reinj_1_4 7840 65971 40451 Mix4_TiO2_Reinj_1_4 7840 P31350 P31350 P31350 >sp|P31350|RIR2_HUMAN Ribonucleoside-diphosphate reductase subunit M2 OS=Homo sapiens GN=RRM2 PE=1 SV=1 1 76.0471 1 105.433 1.97799E-10 133.12 0 0 1 76.0471 1.468E-10 134.22 1 S PQQLQLSPLKGLS CDK1;CDK2;NEK6;Proline-directed 0.0057 1.468E-10 134.22 _VPLAPITDPQQLQLpSPLK_ VPLAPITDPQQLQLS(1)PLK VPLAPIT(-76.05)DPQQLQLS(76.05)PLK 15 2 1019.5528 0.38827 1023800 180240 0 0 843610 0 0 0 611 489;765 85;87 87 6517;6518 7456;7458 65849 40340 Mix4_TiO2_1_4 3192 65843 40338 Mix4_TiO2_Reinj_1_4 4150 P31483;Q01085 P31483;Q01085 Q01085 >sp|P31483|TIA1_HUMAN Nucleolysin TIA-1 isoform p40 OS=Homo sapiens GN=TIA1 PE=1 SV=3;>sp|Q01085|TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens GN=TIAL1 PE=1 SV=1 0.475987 0 0.475987 0 0.00313545 79.307 0.0645788 -11.2967 0.0982634 39.063 0.169348 -5.49708 0.00237493 124.16 1 S NWATTPSSQKKDT 0.00237493 124.16 _VNWATTPpSSQKK_ VNWAT(0.005)T(0.043)PS(0.476)S(0.476)QKK VNWAT(-19.54)T(-10.47)PS(0)S(0)QKK 8 2 713.83995 -0.67539 0 0 0 0 0 0 0 0 0 612 489;765 86;88 88 6517;6518 7456;7458 65849 40340 Mix4_TiO2_1_4 3192 65843 40338 Mix4_TiO2_Reinj_1_4 4150 P31483;Q01085 P31483;Q01085 Q01085 >sp|P31483|TIA1_HUMAN Nucleolysin TIA-1 isoform p40 OS=Homo sapiens GN=TIA1 PE=1 SV=3;>sp|Q01085|TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens GN=TIAL1 PE=1 SV=1 0.475987 0 0.475987 0 0.00313545 79.307 0.000357653 -33.863 0.0982634 39.063 0.169348 -5.49708 0.00237493 124.16 1 S WATTPSSQKKDTS CK1 0.143 0.00237493 124.16 _VNWATTPpSSQKK_ VNWAT(0.005)T(0.043)PS(0.476)S(0.476)QKK VNWAT(-19.54)T(-10.47)PS(0)S(0)QKK 9 2 713.83995 -0.67539 0 0 0 0 0 0 0 0 0 613 490 122 122 5327 6065;6066;6067 51733 31681 Mix4_InSol_TiO2_1 5882 51735 31683 Mix4_TiO2_Reinj_1_4 5424 P31749 P31749 P31749 >sp|P31749|AKT1_HUMAN RAC-alpha serine/threonine-protein kinase OS=Homo sapiens GN=AKT1 PE=1 SV=2 0.75711 6.58311 0.364133 0.195322 1.72724 5.7937 0.499468 0 0.0268011 59.279 0.75711 6.58311 0.412145 36.85 0.131241 -5.58659 1.73471 5.5866 1 S EEMDFRSGSPSDN GSK3 0.081 0.00584997 73.328 _pSGSPSDNSGAEEMEVSLAKPK_ S(0.757)GS(0.166)PS(0.038)DNS(0.038)GAEEMEVSLAKPK S(6.58)GS(-6.58)PS(-12.97)DNS(-12.97)GAEEMEVS(-36.85)LAKPK 1 3 733.98736 -0.11836 261520 0 0 0 0 0 261520 0 614 490 124 124 5327 6065;6066;6067 51735 31683 Mix4_TiO2_Reinj_1_4 5424 51735 31683 Mix4_TiO2_Reinj_1_4 5424 P31749 P31749 P31749 >sp|P31749|AKT1_HUMAN RAC-alpha serine/threonine-protein kinase OS=Homo sapiens GN=AKT1 PE=1 SV=2 0.51353 0.970947 0.348119 -0.195322 1.72724 5.7937 0.51353 0.970947 0.00584997 73.328 0.166283 -6.58311 0.412145 36.85 0.131241 -5.58659 1.73471 5.5866 1 S MDFRSGSPSDNSG CAMK2;CK2;PKA/AKT;Proline-directed 0.00111111 0.00584997 73.328 _SGpSPSDNSGAEEMEVSLAKPK_ S(0.411)GS(0.514)PS(0.074)DNS(0.001)GAEEMEVSLAKPK S(-0.97)GS(0.97)PS(-8.39)DNS(-25.77)GAEEMEVS(-73.33)LAKPK 3 3 733.98736 0.28394 541560 0 0 0 541560 0 0 0 615 490 129 129 5327 6065;6066;6067 51751 31687 Mix4_TiO2_Reinj_1_4 4382 51751 31687 Mix4_TiO2_Reinj_1_4 4382 P31749 P31749 P31749 >sp|P31749|AKT1_HUMAN RAC-alpha serine/threonine-protein kinase OS=Homo sapiens GN=AKT1 PE=1 SV=2 0.999475 34.167 0.0959159 -5.7937 1.72724 5.7937 0.999475 34.167 0.0268011 59.279 0.0382253 -12.9681 0.412145 36.85 0.475037 5.58659 1.73471 5.5866 2 S GSPSDNSGAEEME CK1;CK2 0.081 0.0268011 59.279 _pSGSPSDNpSGAEEM(ox)EVSLAKPK_ S(0.499)GS(0.499)PS(0.001)DNS(0.999)GAEEMEVSLAKPK S(0)GS(0)PS(-26.61)DNS(34.17)GAEEMEVS(-39.43)LAKPK 8 3 765.97444 0.2791 171830 0 0 0 171830 0 0 0 616 491 126 126 666 766;767 6398 3791 Mix4_TiO2_1_4 3264 6399 3792 Mix4_TiO2_Reinj_1_4 3824 P31751 P31751 P31751 >sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase OS=Homo sapiens GN=AKT2 PE=1 SV=2 0.997461 25.9429 0.997461 25.9429 1.36083E-21 170.82 0.995931 23.8874 2.36739E-26 189.34 0.494235 0 0.442302 34.095 0.499968 0 0.00659177 74.103 1 S MDYKCGSPSDSST CK2;GSK3;Proline-directed 0.05 2.36739E-26 189.34 _CGpSPSDSSTTEEM(ox)EVAVSK_ CGS(0.997)PS(0.003)DSSTTEEMEVAVSK CGS(25.94)PS(-25.94)DS(-74.87)S(-82.15)T(-89.33)T(-104.58)EEMEVAVS(-170.82)K 3 2 1048.9054 0.402 334290 71103 0 0 232820 0 0 30368 617 491 128 128 666 766;767 6392 3790 Mix4_InSol_Tio2_Reinj_2 4284 6399 3792 Mix4_TiO2_Reinj_1_4 3824 P31751 P31751 P31751 >sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase OS=Homo sapiens GN=AKT2 PE=1 SV=2 0.499968 0 0.00253865 -25.9429 1.36083E-21 170.82 0.00406904 -23.8874 2.36739E-26 189.34 0.494235 0 0.442302 34.095 0.499968 0 0.00659177 74.103 1 S YKCGSPSDSSTTE 2.36739E-26 189.34 _CGpSPSDSSTTEEMEVAVSK_ CGS(0.5)PS(0.5)DSSTTEEMEVAVSK CGS(0)PS(0)DS(-42.4)S(-41.61)T(-60.34)T(-65.92)EEMEVAVS(-74.1)K 5 2 1040.908 -0.12706 30368 0 0 0 0 0 0 30368 618 491 34 34 5165 5880 50057 30600 Mix4_TiO2_Reinj_1_4 5102 50057 30600 Mix4_TiO2_Reinj_1_4 5102 P31751 P31751 P31751 >sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase OS=Homo sapiens GN=AKT2 PE=1 SV=2 0.999822 40.5044 0.996335 27.3537 0.259909 27.354 0.999822 40.5044 0.0755427 40.504 1 S LLKSDGSFIGYKE CK1;PLK1 0.033462 0.0755427 40.504 _SDGpSFIGYK_ SDGS(1)FIGYK S(-40.5)DGS(40.5)FIGY(-40.5)K 4 2 527.21807 -0.47802 76233 13976 0 0 62257 0 0 0 619 492;493 216;201 216 560 640 5305 3205 Mix4_TiO2_Reinj_1_4 9000 5304 3204 Mix4_TiO2_Reinj_1_2 7615 P31942;P31942-3;P31942-4;P31942-5;P31942-6;P31942-2 P31942;P31942-2 P31942 >sp|P31942|HNRH3_HUMAN Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens GN=HNRNPH3 PE=1 SV=2;>sp|P31942-3|HNRH3_HUMAN Isoform 2H9B of Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens GN=HNRNPH3;>sp|P31942-4|HNRH3_HUMAN Isoform 2H9C of H 1 90.5251 0 0 1 90.5251 5.72785E-06 107.27 1 S DIANFFSPLNPIR Proline-directed 0.05 5.72785E-06 107.27 _ATENDIANFFpSPLNPIR_ ATENDIANFFS(1)PLNPIR AT(-90.53)ENDIANFFS(90.53)PLNPIR 11 3 666.98221 0.15973 175280 2.9204 0 0 0 175280 0 0 0 620 494;643 310;310 310 561 642 5310 3208 Mix4_TiO2_Reinj_1_4 8993 5310 3208 Mix4_TiO2_Reinj_1_4 8993 P31943;P52597 P31943;P52597 P31943 >sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens GN=HNRNPH1 PE=1 SV=4;>sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens GN=HNRNPF PE=1 SV=3 1 128.432 1 100.812 4.87215E-16 157.5 1 128.432 5.65142E-26 196.82 1 S DIYNFFSPLNPVR Proline-directed 0.05 5.65142E-26 196.82 _ATENDIYNFFpSPLNPVR_ ATENDIYNFFS(1)PLNPVR AT(-150.71)ENDIY(-128.43)NFFS(128.43)PLNPVR 11 2 1038.975 0.84121 539500 95488 0 0 444010 0 0 0 621 494 63 63 1558 1749 14236 8662 Mix4_TiO2_Reinj_1_4 6153 14235 8661 Mix4_TiO2_1_4 5502 P31943 P31943 P31943 >sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens GN=HNRNPH1 PE=1 SV=4 1 151.648 1 153.43 2.31902E-21 167.24 1 151.648 3.79683E-21 161.69 1 S AFVELESEDEVKL CK2 0.117 2.31902E-21 167.24 _EGRPSGEAFVELEpSEDEVK_ EGRPSGEAFVELES(1)EDEVK EGRPS(-151.65)GEAFVELES(151.65)EDEVK 14 3 729.65449 0.65289 744620 0.6702 150360 0 0 594270 0 0 0 622 494 104 104 2674 3045 25054 15489 Mix4_InSol_TiO2_1 4302 25077 15516 Mix4_TiO2_Reinj_1_4 4084 P31943;P55795 P31943 P31943 >sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens GN=HNRNPH1 PE=1 SV=4;>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens GN=HNRNPH2 PE=1 SV=1 0.999323 33.5173 0.991472 20.8134 1.90422E-20 191.28 0 0 0.998972 30.5904 8.65451E-26 202.3 0 0 0.999323 33.5173 1.18713E-25 197.73 0.965575 14.7497 8.14919E-20 178.35 1 S KHTGPNSPDTAND CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 8.65451E-26 202.3 _HTGPNpSPDTANDGFVR_ HTGPNS(0.999)PDTANDGFVR HT(-33.52)GPNS(33.52)PDT(-36.33)ANDGFVR 6 2 882.8705 0.39652 11756000 38.04 3719300 0 0 4861100 0 2221400 954120 623 499 930 930 2601 2958 24310 15107 Mix4_TiO2_Reinj_1_1 1502 24311 15108 Mix4_TiO2_Reinj_1_5 1924 P33527;P33527-3;P33527-2;P33527-5;P33527-9;P33527-4;P33527-7;P33527-6;P33527-8 P33527 P33527 >sp|P33527|MRP1_HUMAN Multidrug resistance-associated protein 1 OS=Homo sapiens GN=ABCC1 PE=1 SV=3;>sp|P33527-3|MRP1_HUMAN Isoform Delexon-18 of Multidrug resistance-associated protein 1 OS=Homo sapiens GN=ABCC1;>sp|P33527-2|MRP1_HUMAN Isoform Delexon-17 o 0.980618 17.041 0.980618 17.041 0.0412294 48.905 0 0 0 0 1 S ISRHHNSTAELQK CK2 0.117 0.0412294 48.905 _HHNpSTAELQK_ HHNS(0.981)T(0.019)AELQK HHNS(17.04)T(-17.04)AELQK 4 3 415.51883 0.11146 382490 0 0 0 382490 0 0 0 624 499 915 915 4640 5266 43973 26951 Mix4_TiO2_Reinj_1_1 3731 43971 26949 Mix4_TiO2_1_1 3236 P33527;P33527-3;P33527-2;P33527-5;P33527-9;P33527-4;P33527-7;P33527-6;P33527-8 P33527 P33527 >sp|P33527|MRP1_HUMAN Multidrug resistance-associated protein 1 OS=Homo sapiens GN=ABCC1 PE=1 SV=3;>sp|P33527-3|MRP1_HUMAN Isoform Delexon-18 of Multidrug resistance-associated protein 1 OS=Homo sapiens GN=ABCC1;>sp|P33527-2|MRP1_HUMAN Isoform Delexon-17 o 0.448452 1.71363 0.397217 1.01666 0.0729624 48.553 0 0 0.448452 1.71363 0.208699 35.755 0 0 0 0 0 0 1 S QLQRQLSSSSSYS CAMK2;CHK1;CHK1/2;GSK3;PKD 0.003192 0.0729624 48.553 _QLpSSSSSYSGDISR_ QLS(0.448)S(0.302)S(0.239)S(0.008)S(0.001)YSGDISR QLS(1.71)S(-1.71)S(-2.73)S(-17.38)S(-25.14)Y(-29.84)S(-35.23)GDIS(-35.23)R 3 2 777.3276 1.0239 0 0 0 0 0 0 0 0 625 499 919 919 4640 5266 43972 26950 Mix4_TiO2_Reinj_1_1 3664 43971 26949 Mix4_TiO2_1_1 3236 P33527;P33527-3;P33527-2;P33527-5;P33527-9;P33527-4;P33527-7;P33527-6;P33527-8 P33527 P33527 >sp|P33527|MRP1_HUMAN Multidrug resistance-associated protein 1 OS=Homo sapiens GN=ABCC1 PE=1 SV=3;>sp|P33527-3|MRP1_HUMAN Isoform Delexon-18 of Multidrug resistance-associated protein 1 OS=Homo sapiens GN=ABCC1;>sp|P33527-2|MRP1_HUMAN Isoform Delexon-17 o 0.415499 0 0.00624053 -18.0381 0.0729624 48.553 0 0 0.415499 0 0.208699 35.755 0 0 0 0 0 0 1 S QLSSSSSYSGDIS CK1 0.081 0.0729624 48.553 _QLSSSSpSYSGDISR_ QLSS(0.001)S(0.011)S(0.078)S(0.415)Y(0.415)S(0.078)GDISR QLS(-35.76)S(-24.73)S(-15.86)S(-7.25)S(0)Y(0)S(-7.25)GDIS(-35.76)R 7 2 777.3276 0.4946 0 0 0 0 0 0 0 0 626 501 436 436 2677 3049 25133 15534 Mix4_TiO2_Reinj_1_5 6022 25133 15534 Mix4_TiO2_Reinj_1_5 6022 P33981 P33981 P33981 >sp|P33981|TTK_HUMAN Dual specificity protein kinase TTK OS=Homo sapiens GN=TTK PE=1 SV=2 0.999962 45.5721 0.968796 16.4773 0.000292713 89.463 0.999962 45.5721 7.15215E-24 159.74 0 0 0.412256 -0.00992164 0.0135933 64.871 1 S FSVSKQSPPISTS CK1;GSK3;Proline-directed 0.05 7.15215E-24 159.74 _HTTFEQPVFSVSKQpSPPISTSK_ HTTFEQPVFSVSKQS(1)PPISTSK HT(-150.19)T(-138.79)FEQPVFS(-86.74)VS(-62.3)KQS(45.57)PPIS(-45.57)T(-53.34)S(-53.34)K 15 3 838.0755 0.40337 2131100 362410 0 0 1768700 0 0 0 627 501 442 442 2677 3049 25130 15531 Mix4_InSol_Tio2_Reinj_1 6524 25133 15534 Mix4_TiO2_Reinj_1_5 6022 P33981 P33981 P33981 >sp|P33981|TTK_HUMAN Dual specificity protein kinase TTK OS=Homo sapiens GN=TTK PE=1 SV=2 0.413199 0.00992164 0.00426901 -23.559 0.000292713 89.463 0.000350439 -34.4099 7.15215E-24 159.74 0 0 0.413199 0.00992164 0.0135933 64.871 1 S SPPISTSKWFDPK 7.15215E-24 159.74 _HTTFEQPVFSVSKQSPPISTpSK_ HTTFEQPVFSVS(0.003)KQS(0.412)PPIS(0.086)T(0.086)S(0.413)K HT(-64.87)T(-64.87)FEQPVFS(-40.95)VS(-21.86)KQS(-0.01)PPIS(-6.82)T(-6.82)S(0.01)K 21 3 838.0755 -0.35146 0 0 0 0 0 0 0 0 628 508 368 368 1852;3011 2093;3425 17032 10260 Mix4_TiO2_Reinj_1_5 2343 28770 17914 Mix4_TiO2_Reinj_1_5 2183 P35251;P35251-2 P35251 P35251 >sp|P35251|RFC1_HUMAN Replication factor C subunit 1 OS=Homo sapiens GN=RFC1 PE=1 SV=4;>sp|P35251-2|RFC1_HUMAN Isoform 2 of Replication factor C subunit 1 OS=Homo sapiens GN=RFC1 0.999978 49.6251 0.947221 15.5502 0.439639 15.55 0.999978 49.6251 0.00936131 63.991 1 S AKKESVSPEDSEK CK2;GSK3;Proline-directed 0.05 0.00936131 63.991 _ESVpSPEDSEK_ ESVS(1)PEDSEK ES(-49.63)VS(49.63)PEDS(-49.63)EK 4 2 593.7292 0.37461 243300 41678 0 0 201620 0 0 0 629 510 275 275 722 827 6948 4122 Mix4_InSol_TiO2_1 3734 6948 4122 Mix4_InSol_TiO2_1 3734 P35367 P35367 P35367 >sp|P35367|HRH1_HUMAN Histamine H1 receptor OS=Homo sapiens GN=HRH1 PE=1 SV=1 0.949825 13.2534 0 0 0 0 0.734541 4.53799 0.0112627 72.109 0.949825 13.2534 0.00225731 81.241 0.0710399 -11.1593 0.0267969 60.011 1 S GGSVLKSPSQTPK CK1;Proline-directed 0.05 0.00225731 81.241 _DAGGGSVLKpSPSQTPK_ DAGGGS(0.003)VLKS(0.95)PS(0.045)QT(0.002)PK DAGGGS(-24.86)VLKS(13.25)PS(-13.25)QT(-26.42)PK 10 2 804.88508 0.21127 169660 0 0 0 119780 0 49876 0 630 510 277 277 722 827 6949 4123 Mix4_InSol_Tio2_Reinj_1 3703 6948 4122 Mix4_InSol_TiO2_1 3734 P35367 P35367 P35367 >sp|P35367|HRH1_HUMAN Histamine H1 receptor OS=Homo sapiens GN=HRH1 PE=1 SV=1 0.92775 11.1593 0 0 0 0 0.258355 -4.53799 0.0112627 72.109 0.0449057 -13.2534 0.00225731 81.241 0.92775 11.1593 0.0267969 60.011 1 S SVLKSPSQTPKEM CHK1;PKD 0.020748 0.00225731 81.241 _DAGGGSVLKSPpSQTPK_ DAGGGSVLKS(0.071)PS(0.928)QT(0.001)PK DAGGGS(-33.84)VLKS(-11.16)PS(11.16)QT(-30.5)PK 12 2 804.88508 -0.15037 62638 0 0 0 0 0 0 62638 631 512 1101 1101 2655 3020 24782 15346 Mix4_TiO2_1_3 2728 24780 15344 Mix4_InSol_TiO2_1 3706 P35568 P35568 P35568 >sp|P35568|IRS1_HUMAN Insulin receptor substrate 1 OS=Homo sapiens GN=IRS1 PE=1 SV=1 0.951373 15.066 0.951373 15.066 0.428315 24.778 0 0 0 0 0.416491 -1.16533 0.0552693 52.755 0.886622 9.07681 0.245523 33.911 1 S CRRRHSSETFSST CAMK2;GSK3;PIM1/2;PKA/AKT 0.000138852 0.0552693 52.755 _HSpSETFSSTPSATR_ HS(0.03)S(0.951)ET(0.003)FS(0.003)S(0.003)T(0.003)PS(0.003)AT(0.003)R HS(-15.07)S(15.07)ET(-24.78)FS(-24.78)S(-24.78)T(-24.78)PS(-24.78)AT(-24.78)R 3 2 787.82777 1.2274 56039 13657 0 0 0 0 0 42382 632 514 1943 1943 3026 3440 28846 17954 Mix4_TiO2_Reinj_1_5 2039 28846 17954 Mix4_TiO2_Reinj_1_5 2039 P35579;P35579-2 P35579 P35579 >sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH9 PE=1 SV=4;>sp|P35579-2|MYH9_HUMAN Isoform 2 of Myosin-9 OS=Homo sapiens GN=MYH9 1 106.513 1 46.9147 0.0798589 46.915 0 0 1 106.513 0.000135487 106.51 0 0 0 0 1 S KGAGDGSDEEVDG CK2 0.117 0.000135487 106.51 _KGAGDGpSDEEVDGK_ KGAGDGS(1)DEEVDGK KGAGDGS(106.51)DEEVDGK 7 2 722.2854 0.16651 279900 23004 0 0 256900 0 0 0 633 515 859 859 5771 6576 56840 34671 Mix4_TiO2_1_3 4319 56840 34671 Mix4_TiO2_1_3 4319 P35606 P35606 P35606 >sp|P35606|COPB2_HUMAN Coatomer subunit beta' OS=Homo sapiens GN=COPB2 PE=1 SV=2 0.968413 14.8684 0.968413 14.8684 3.23268E-07 102.42 0 0 0 0 1 S LDGKPASPTPVIV ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.23268E-07 102.42 _STAQQELDGKPApSPTPVIVASHTANK_ STAQQELDGKPAS(0.968)PT(0.032)PVIVASHTANK S(-50.15)T(-49.5)AQQELDGKPAS(14.87)PT(-14.87)PVIVAS(-63.45)HT(-73.87)ANK 13 3 909.78316 -0.51414 117910 117910 0 0 0 0 0 0 634 518 667 667 2925 3329 27936 17380 Mix4_TiO2_Reinj_1_1 2592 27936 17380 Mix4_TiO2_Reinj_1_1 2592 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 1 98.8943 0.999999 60.0323 0.0246307 60.032 0 0 1 98.8943 0.000223472 98.894 0.999828 37.6317 0.171238 37.632 0.999579 33.7555 0.248615 33.756 1 S PAAKPGSPQAKSL ERK/MAPK;Proline-directed 0.0025 0.000223472 98.894 _ITPPAAKPGpSPQAK_ ITPPAAKPGS(1)PQAK IT(-98.89)PPAAKPGS(98.89)PQAK 10 2 721.87379 0.29767 670060 105580 0 0 209840 0 167250 187390 635 518 457 457 3333 3772 31507 19503 Mix4_TiO2_1_1 7982 31509 19505 Mix4_TiO2_Reinj_1_1 8676 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 0.643666 5.64473 0.643666 5.64473 0.494865 64.412 0 0 0.364939 0 0.0081721 84.707 1 S AAAAPASLPPSSP GSK3 0.081 0.0081721 84.707 _LDASAAAAPApSLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLK_ LDAS(0.019)AAAAPAS(0.644)LPPS(0.175)S(0.053)PAAPIAT(0.054)FS(0.054)LLPAGGAPTVFSFGSSSLK LDAS(-15.35)AAAAPAS(5.64)LPPS(-5.64)S(-10.82)PAAPIAT(-10.74)FS(-10.74)LLPAGGAPT(-34.17)VFS(-44.5)FGS(-46.88)S(-48.65)S(-48.65)LK 11 4 1045.2829 0.33997 190670 190670 0 0 0 0 0 0 636 518 461 461 3333 3772 31508 19504 Mix4_TiO2_1_1 7994 31509 19505 Mix4_TiO2_Reinj_1_1 8676 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 0.378132 0 0.378132 0 0.494865 64.412 0 0 0.364939 0 0.0081721 84.707 1 S PASLPPSSPAAPI CK1;NEK6 0.076 0.0081721 84.707 _LDASAAAAPASLPPpSSPAAPIATFSLLPAGGAPTVFSFGSSSLK_ LDAS(0.001)AAAAPAS(0.012)LPPS(0.378)S(0.378)PAAPIAT(0.161)FS(0.061)LLPAGGAPT(0.006)VFS(0.001)FGS(0.001)S(0.001)S(0.001)LK LDAS(-25.2)AAAAPAS(-14.88)LPPS(0)S(0)PAAPIAT(-3.71)FS(-7.94)LLPAGGAPT(-18.28)VFS(-24.6)FGS(-28.14)S(-28.14)S(-28.14)LK 15 3 1393.3748 0.59083 0 0 0 0 0 0 0 0 637 518 462 462 3333 3772 31508 19504 Mix4_TiO2_1_1 7994 31509 19505 Mix4_TiO2_Reinj_1_1 8676 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 0.378132 0 0.378132 0 0.494865 64.412 0 0 0.102009 -5.53581 0.0081721 84.707 1 S ASLPPSSPAAPIA ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0081721 84.707 _LDASAAAAPASLPPpSSPAAPIATFSLLPAGGAPTVFSFGSSSLK_ LDAS(0.001)AAAAPAS(0.012)LPPS(0.378)S(0.378)PAAPIAT(0.161)FS(0.061)LLPAGGAPT(0.006)VFS(0.001)FGS(0.001)S(0.001)S(0.001)LK LDAS(-25.2)AAAAPAS(-14.88)LPPS(0)S(0)PAAPIAT(-3.71)FS(-7.94)LLPAGGAPT(-18.28)VFS(-24.6)FGS(-28.14)S(-28.14)S(-28.14)LK 16 3 1393.3748 0.59083 0 0 0 0 0 0 0 0 638 518 430 430 5564 6339;6340 54469 33348 Mix4_TiO2_Reinj_1_1 2373 54469 33348 Mix4_TiO2_Reinj_1_1 2373 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 1 65.4679 0.827655 7.60235 0.0559745 55.66 1 65.4679 8.46897E-13 147.06 0.0973486 -9.96668 0.846307 18.987 0.603179 5.36358 0.822766 19.667 1 S GERQPKSPGSTPT ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 8.46897E-13 147.06 _pSPGSTPTTPTSSQAPQK_ S(1)PGSTPTTPTSSQAPQK S(65.47)PGS(-66.77)T(-65.47)PT(-105.08)T(-119.76)PT(-112.05)S(-127.17)S(-133.51)QAPQK 1 2 876.39601 -0.25153 161520 42702 0 0 118820 0 0 0 639 518 433 433 5564 6339;6340 54462 33341 Mix4_InSol_TiO2_1 2613 54465 33345 Mix4_TiO2_Reinj_1_1 2097 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 0.716632 7.54904 0.639927 2.65773 4.27801E-06 109.99 0.667507 3.25755 9.08297E-10 134.9 0.716632 7.54904 0.846307 18.987 0.294575 -5.36358 0.822766 19.667 2 S QPKSPGSTPTTPT CK1 0.081 9.08297E-10 134.9 _SPGpSTPpTTPTSSQAPQK_ S(0.097)PGS(0.717)T(0.149)PT(0.558)T(0.365)PT(0.039)S(0.038)S(0.038)QAPQK S(-9.97)PGS(7.55)T(-7.55)PT(1.98)T(-1.98)PT(-17.58)S(-18.11)S(-18.62)QAPQK 4 2 916.37918 1.3407 378210 61612 0 0 299580 0 17020 0 640 521 293 293 1644;4458 1844;5069 42345 26052 Mix4_TiO2_2_4 3397 42343 26048 Mix4_TiO2_1_4 3540 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.649709 2.6829 0.5 0 8.31987E-20 178 0.649709 2.6829 0.117721 46.04 0.5 0 1.83488E-25 164.03 0 0 0 0 0 0 1 S EEGEPHSISPRPR 8.31987E-20 178 _PVVDGEEGEPHpSISPR_ PVVDGEEGEPHS(0.65)IS(0.35)PR PVVDGEEGEPHS(2.68)IS(-2.68)PR 12 2 892.89618 -0.54281 4894700 966230 108040 0 3820400 0 0 0 641 521 295 295 1644;4458 1844;5069 42343 26048 Mix4_TiO2_1_4 3540 42343 26048 Mix4_TiO2_1_4 3540 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.999848 38.1789 0.999848 38.1789 8.31987E-20 178 0.43831 -1.07716 0.117721 46.04 0.999679 34.9334 1.83488E-25 164.03 0 0 0 0 0 0 1 S GEPHSISPRPRPP CDK1;Proline-directed 0.0057 8.31987E-20 178 _PVVDGEEGEPHSIpSPR_ PVVDGEEGEPHSIS(1)PR PVVDGEEGEPHS(-38.18)IS(38.18)PR 14 2 892.89618 -0.13085 29365000 5151900 0 0 24213000 0 0 0 642 521 23 23 3169;4927 3597;5601 47295 28884 Mix4_TiO2_Reinj_1_4 7746 47295 28884 Mix4_TiO2_Reinj_1_4 7746 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.807901 7.03737 0.790345 6.02794 1.06584E-12 128.76 0 0 0.807901 7.03737 6.39521E-27 166.38 0 0 0.804728 7.03617 2.76751E-05 98.157 0.201976 0 1.70775 29.813 1 S TIAEGPSPTSEGA Proline-directed 0.05 6.39521E-27 166.38 _RKPVLPALTINPTIAEGPpSPTSEGASEANLVDLQK_ RKPVLPALTINPTIAEGPS(0.808)PT(0.16)S(0.032)EGASEANLVDLQK RKPVLPALT(-107.03)INPT(-92.83)IAEGPS(7.04)PT(-7.04)S(-13.99)EGAS(-41.78)EANLVDLQK 19 3 1231.9748 0.4988 18497000 1.6658 104550 0 0 17842000 0 550330 0 643 521 26 26 3169;4927 3597;5601 30048 18695 Mix4_TiO2_Reinj_1_4 8061 47295 28884 Mix4_TiO2_Reinj_1_4 7746 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.381284 1.00313 0.365052 0.613946 1.06584E-12 128.76 0 0 0.381284 1.00313 6.39521E-27 166.38 0 0 0.108922 -7.57485 2.76751E-05 98.157 0.201976 0 1.70775 29.813 1 S EGPSPTSEGASEA CK1;GSK3 0.081 6.39521E-27 166.38 _KPVLPALTINPTIAEGPSPTpSEGASEANLVDLQK_ KPVLPALTINPTIAEGPS(0.303)PT(0.303)S(0.381)EGAS(0.013)EANLVDLQK KPVLPALT(-89.89)INPT(-62.24)IAEGPS(-1)PT(-1)S(1)EGAS(-14.53)EANLVDLQK 21 4 885.20765 0.12956 0 0 0 0 0 0 0 0 0 644 521 30 30 3169;4927 3597;5601 47296 28885 Mix4_TiO2_Reinj_1_4 7721 47295 28884 Mix4_TiO2_Reinj_1_4 7746 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.261676 0 0.00717596 -17.9277 1.06584E-12 128.76 0 0 0.261676 0 6.39521E-27 166.38 0 0 0.00320522 -23.9979 2.76751E-05 98.157 0.00885575 -13.5808 1.70775 29.813 1 S PTSEGASEANLVD CK1 0.143 6.39521E-27 166.38 _RKPVLPALTINPTIAEGPSPTpSEGASEANLVDLQK_ RKPVLPALTINPTIAEGPS(0.238)PT(0.238)S(0.262)EGAS(0.262)EANLVDLQK RKPVLPALT(-50.5)INPT(-50.5)IAEGPS(-0.41)PT(-0.41)S(0)EGAS(0)EANLVDLQK 26 5 739.5878 0.23989 0 0 0 0 0 0 0 0 0 645 521;778 222;218 222 3325 3761;3762 31419 19475 Mix4_TiO2_Reinj_1_4 8995 31417 19473 Mix4_TiO2_Reinj_1_4 8785 P36507;Q02750 P36507;Q02750 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1;>sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2 0.993958 22.1624 0.0204515 -16.8027 1.58563E-25 175.6 0.993958 22.1624 5.90012E-39 200.95 0 0 0.127566 -8.348 3.24595E-24 168.6 0.272057 -2.24194 0.000145158 94.198 1 S SGQLIDSMANSFV GSK3;NEK6 0.076 5.90012E-39 200.95 _LCDFGVSGQLIDpSMANSFVGTR_ LCDFGVSGQLIDS(0.994)MANS(0.006)FVGTR LCDFGVS(-60.26)GQLIDS(22.16)MANS(-22.16)FVGT(-73.8)R 13 3 818.69916 0.36644 275810 0 0 0 275810 0 0 0 646 521;778 226;222 226 3325 3761;3762 31417 19473 Mix4_TiO2_Reinj_1_4 8785 31417 19473 Mix4_TiO2_Reinj_1_4 8785 P36507;Q02750 P36507;Q02750 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1;>sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2 1 64.2524 0.999943 44.2281 1.58563E-25 175.6 1 64.2524 5.90012E-39 200.95 0 0 0.999796 36.8974 3.24595E-24 168.6 0.973715 15.7162 0.000145158 94.198 1 S IDSMANSFVGTRS CK1 0.143 5.90012E-39 200.95 _LCDFGVSGQLIDSMANpSFVGTR_ LCDFGVSGQLIDSMANS(1)FVGTR LCDFGVS(-161.61)GQLIDS(-88.18)MANS(64.25)FVGT(-64.25)R 17 3 818.69916 -0.087494 5094900 843500 0 0 2918800 0 1140800 191790 647 523 295 295 2829 3222 27012 16885 Mix4_TiO2_Reinj_1_4 3712 27011 16884 Mix4_TiO2_Reinj_1_4 3695 P36578 P36578 P36578 >sp|P36578|RL4_HUMAN 60S ribosomal protein L4 OS=Homo sapiens GN=RPL4 PE=1 SV=5 1 30.4503 1 28.8106 0.000782858 80.936 1 2.47524 0.044654 48.746 1 30.4503 0.00172684 91.853 1 33.0864 0.00128562 86.75 1 20.6506 0.0409042 49.934 1 S LSRILKSPEIQRA Proline-directed 0.05 0.00172684 91.853 _ILKpSPEIQR_ ILKS(1)PEIQR ILKS(30.45)PEIQR 4 3 388.54432 0.096606 5135700 760950 91680 0 2935400 0 767420 580210 648 523 12 12 4426 5035 42116 25950 Mix4_TiO2_1_4 4438 42116 25950 Mix4_TiO2_1_4 4438 P36578 P36578 P36578 >sp|P36578|RL4_HUMAN 60S ribosomal protein L4 OS=Homo sapiens GN=RPL4 PE=1 SV=5 0.999223 35.0328 0.999223 35.0328 0.000947384 93.017 0 0 0.829161 9.32348 0.692218 19.264 1 S PLISVYSEKGESS CK1 0.081 0.000947384 93.017 _PLISVYpSEKGESSGK_ PLISVYS(0.999)EKGESSGK PLIS(-60.56)VY(-38.26)S(35.03)EKGES(-35.03)S(-35.03)GK 7 2 830.89512 0.45849 265920 45375 0 0 220550 0 0 0 649 523 17 17 4426 5035 42115 25949 Mix4_TiO2_1_4 4419 42116 25950 Mix4_TiO2_1_4 4438 P36578 P36578 P36578 >sp|P36578|RL4_HUMAN 60S ribosomal protein L4 OS=Homo sapiens GN=RPL4 PE=1 SV=5 0.237345 0 0.237345 0 0.000947384 93.017 0 0 0.00982358 -19.2637 0.692218 19.264 1 S YSEKGESSGKNVT 0.000947384 93.017 _PLISVpYSEKGESSGK_ PLIS(0.051)VY(0.237)S(0.237)EKGES(0.237)S(0.237)GK PLIS(-6.71)VY(0)S(0)EKGES(0)S(0)GK 12 3 554.26584 -0.093431 0 0 0 0 0 0 0 0 650 523 18 18 4426 5035 42115 25949 Mix4_TiO2_1_4 4419 42116 25950 Mix4_TiO2_1_4 4438 P36578 P36578 P36578 >sp|P36578|RL4_HUMAN 60S ribosomal protein L4 OS=Homo sapiens GN=RPL4 PE=1 SV=5 0.237345 0 0.237345 0 0.000947384 93.017 0 0 0.00982358 -19.2637 0.692218 19.264 1 S SEKGESSGKNVTL 0.000947384 93.017 _PLISVpYSEKGESSGK_ PLIS(0.051)VY(0.237)S(0.237)EKGES(0.237)S(0.237)GK PLIS(-6.71)VY(0)S(0)EKGES(0)S(0)GK 13 3 554.26584 -0.093431 0 0 0 0 0 0 0 0 651 526 485 485 2441 2768 22949 14350 Mix4_TiO2_1_5 3985 22949 14350 Mix4_TiO2_1_5 3985 P36956-4;P36956;P36956-2;P36956-3 P36956-4 P36956-4 >sp|P36956-4|SRBP1_HUMAN Isoform 4 of Sterol regulatory element-binding protein 1 OS=Homo sapiens GN=SREBF1;>sp|P36956|SRBP1_HUMAN Sterol regulatory element-binding protein 1 OS=Homo sapiens GN=SREBF1 PE=1 SV=2;>sp|P36956-2|SRBP1_HUMAN Isoform SREBP-1B of 0.77957 7.03827 0.77957 7.03827 2.5048E-08 117.62 0 0 1 S GSGGSGSDSEPDS CK2 0.117 2.5048E-08 117.62 _GSGSGGSGpSDSEPDSPVFEDSK_ GS(0.031)GS(0.031)GGS(0.154)GS(0.78)DS(0.005)EPDSPVFEDSK GS(-14.03)GS(-14.03)GGS(-7.04)GS(7.04)DS(-22.29)EPDS(-65.7)PVFEDS(-117.62)K 9 2 1082.9131 -0.058496 56670 0.22391 56670 0 0 0 0 0 0 652 527 573 573 2057 2331 18875 11520 Mix4_TiO2_Reinj_1_3 5746 18875 11520 Mix4_TiO2_Reinj_1_3 5746 P37173-2;P37173 P37173-2 P37173-2 >sp|P37173-2|TGFR2_HUMAN Isoform 2 of TGF-beta receptor type-2 OS=Homo sapiens GN=TGFBR2;>sp|P37173|TGFR2_HUMAN TGF-beta receptor type-2 OS=Homo sapiens GN=TGFBR2 PE=1 SV=2 0.999988 49.1359 0.999988 49.1359 0.0618115 49.136 0 0 0 0 1 S EHLDRLSGRSCSE PKA 0.042 0.0618115 49.136 _FSELEHLDRLpSGR_ FSELEHLDRLS(1)GR FS(-49.14)ELEHLDRLS(49.14)GR 11 3 546.92604 -0.19704 631070 0 0 0 631070 0 0 0 653 527 576 576 5141 5852 49730 30395 Mix4_TiO2_Reinj_1_5 4334 49730 30395 Mix4_TiO2_Reinj_1_5 4334 P37173-2;P37173 P37173-2 P37173-2 >sp|P37173-2|TGFR2_HUMAN Isoform 2 of TGF-beta receptor type-2 OS=Homo sapiens GN=TGFBR2;>sp|P37173|TGFR2_HUMAN TGF-beta receptor type-2 OS=Homo sapiens GN=TGFBR2 PE=1 SV=2 0.994434 22.5204 0.975421 15.9862 8.56439E-06 101.87 0 0 0.994434 22.5204 1.06687E-12 144.59 0.899055 9.53046 2.50402E-27 126.63 0.98297 17.6184 3.39651E-09 128.11 1 S DRLSGRSCSEEKI CK1;CK2 0.081 1.06687E-12 144.59 _pSCSEEKIPEDGSLNTTK_ S(0.994)CS(0.006)EEKIPEDGSLNTTK S(22.52)CS(-22.52)EEKIPEDGS(-82.07)LNT(-105.1)T(-96.15)K 1 2 987.92173 0.1204 3349600 586740 0 0 1972100 0 366910 423820 654 527 578 578 5141 5852 49726 30391 Mix4_TiO2_1_5 3677 49730 30395 Mix4_TiO2_Reinj_1_5 4334 P37173-2;P37173 P37173-2 P37173-2 >sp|P37173-2|TGFR2_HUMAN Isoform 2 of TGF-beta receptor type-2 OS=Homo sapiens GN=TGFBR2;>sp|P37173|TGFR2_HUMAN TGF-beta receptor type-2 OS=Homo sapiens GN=TGFBR2 PE=1 SV=2 0.641533 2.53033 0.641533 2.53033 8.56439E-06 101.87 0 0 0.431199 -1.2028 1.06687E-12 144.59 0.409405 -1.59137 2.50402E-27 126.63 0.15265 -7.43947 3.39651E-09 128.11 1 S LSGRSCSEEKIPE CAMK2 0.042 1.06687E-12 144.59 _SCpSEEKIPEDGSLNTTK_ S(0.358)CS(0.642)EEKIPEDGSLNTTK S(-2.53)CS(2.53)EEKIPEDGS(-39.47)LNT(-39.47)T(-39.47)K 3 3 658.95025 -0.040512 176270 176270 0 0 0 0 0 0 655 529 208 208 1338;1339 1507;1508 12483 7613 Mix4_InSol_TiO2_1 5137 12483 7613 Mix4_InSol_TiO2_1 5137 P38159 P38159 P38159 >sp|P38159|HNRPG_HUMAN Heterogeneous nuclear ribonucleoprotein G OS=Homo sapiens GN=RBMX PE=1 SV=3 0.99997 47.4491 0.996975 25.1802 0.245239 33.925 0 0 0.999895 39.7999 0.18923 39.8 0.99997 47.4491 0.0438139 55.476 0.949663 18.73 0.586583 18.793 1 S RRDVYLSPRDDGY CDK1;CK2;Proline-directed 0.0057 0.0438139 55.476 _DVYLpSPRDDGYSTK_ DVYLS(1)PRDDGYSTK DVY(-47.45)LS(47.45)PRDDGY(-55.48)S(-51.99)T(-55.48)K 5 2 848.36672 0.53444 1865600 235580 0 0 1188800 0 253540 187650 656 529 215 215 1339 1508 12484 7614 Mix4_InSol_TiO2_2 3847 12483 7613 Mix4_InSol_TiO2_1 5137 P38159 P38159 P38159 >sp|P38159|HNRPG_HUMAN Heterogeneous nuclear ribonucleoprotein G OS=Homo sapiens GN=RBMX PE=1 SV=3 0.339786 0 0.000383793 -33.9249 0.245239 33.925 0 0 0.0293169 -14.7871 0.207036 35.838 0.339786 0 0.0438139 55.476 0.0125382 -18.7933 0.586583 18.793 1 S PRDDGYSTKDSYS CK2;GSK3 0.081 0.0438139 55.476 _DVYLSPRDDGpYSTK_ DVY(0.091)LS(0.225)PRDDGY(0.34)S(0.34)T(0.004)K DVY(-5.71)LS(-1.79)PRDDGY(0)S(0)T(-19.12)K 12 2 848.36672 0.49284 0 0 0 0 0 0 0 0 657 531 13 13 2594;3025 2949;3439 24245 15045 Mix4_TiO2_Reinj_1_4 6169 24245 15045 Mix4_TiO2_Reinj_1_4 6169 P39023 P39023 P39023 >sp|P39023|RL3_HUMAN 60S ribosomal protein L3 OS=Homo sapiens GN=RPL3 PE=1 SV=2 1 75.6666 1 38.9151 0.0978233 38.915 1 75.6666 0.0022011 75.667 0.0165649 -17.7356 0.407366 17.736 1 S SAPRHGSLGFLPR CAMK2 0.042 0.0022011 75.667 _HGpSLGFLPR_ HGS(1)LGFLPR HGS(75.67)LGFLPR 3 2 532.25787 -0.30833 178250 27.831 25026 0 0 153220 0 0 0 658 534 515 515 4979 5661 48034 29375 Mix4_TiO2_Reinj_1_3 2452 48034 29375 Mix4_TiO2_Reinj_1_3 2452 P40222 P40222 P40222 >sp|P40222|TXLNA_HUMAN Alpha-taxilin OS=Homo sapiens GN=TXLNA PE=1 SV=3 0.739832 4.5388 0 0 0.739832 4.5388 0.00266529 84.063 1 S GAQAPSSPRVTEA CDK1;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.00266529 84.063 _RPEGPGAQAPSpSPR_ RPEGPGAQAPS(0.26)S(0.74)PR RPEGPGAQAPS(-4.54)S(4.54)PR 12 2 743.84355 0.20437 190640 0 0 0 190640 0 0 0 659 536 727 727 1995;6046 2257;6896 18133 10818 Mix4_InSol_Tio2_Reinj_1 7871 18133 10818 Mix4_InSol_Tio2_Reinj_1 7871 P40763;P40763-2 P40763 P40763 >sp|P40763|STAT3_HUMAN Signal transducer and activator of transcription 3 OS=Homo sapiens GN=STAT3 PE=1 SV=2;>sp|P40763-2|STAT3_HUMAN Isoform Del-701 of Signal transducer and activator of transcription 3 OS=Homo sapiens GN=STAT3 1 75.8895 0 0 1 67.6189 0.000684915 80.002 1 75.8895 0.000310297 90.327 1 S TIDLPMSPRTLDS CDK1;ERK/MAPK;NEK6;Proline-directed;WW GroupIV 0.0023175 0.000310297 90.327 _FICVTPTTCSNTIDLPMpSPR_ FICVTPTTCSNTIDLPMS(1)PR FICVT(-90.33)PT(-90.33)T(-90.33)CS(-90.33)NT(-75.89)IDLPMS(75.89)PR 18 3 797.35786 0.58492 371730 0 0 0 0 0 200650 171080 660 541 1047 1047 400 457 3788 2251 Mix4_TiO2_2_2 3488 3789 2252 Mix4_TiO2_Reinj_1_5 4388 P41252 P41252 P41252 >sp|P41252|SYIC_HUMAN Isoleucyl-tRNA synthetase, cytoplasmic OS=Homo sapiens GN=IARS PE=1 SV=2 0.661378 2.9244 0.00568087 -22.4311 0.000495464 102.82 0.661378 2.9244 0.316118 26.977 0.545471 0.792094 0.000183297 113.54 0 0 0 0 1 S LKPYPVSPSDKVL CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000183297 113.54 _APLKPYPVpSPSDK_ APLKPY(0.001)PVS(0.661)PS(0.337)DK APLKPY(-26.98)PVS(2.92)PS(-2.92)DK 9 2 739.86817 0.86994 303560 0 30887 0 272680 0 0 0 661 541 1049 1049 400 457 3789 2252 Mix4_TiO2_Reinj_1_5 4388 3789 2252 Mix4_TiO2_Reinj_1_5 4388 P41252 P41252 P41252 >sp|P41252|SYIC_HUMAN Isoleucyl-tRNA synthetase, cytoplasmic OS=Homo sapiens GN=IARS PE=1 SV=2 0.999264 31.3302 0.994319 22.4311 0.000495464 102.82 0.337295 -2.9244 0.316118 26.977 0.999264 31.3302 0.000183297 113.54 0 0 0 0 1 S PYPVSPSDKVLIQ 0.000183297 113.54 _APLKPYPVSPpSDK_ APLKPYPVS(0.001)PS(0.999)DK APLKPY(-69)PVS(-31.33)PS(31.33)DK 11 2 739.86817 0.40153 999260 259170 0 0 740090 0 0 0 662 542 396 396 76 90 885 588 Mix4_InSol_Tio2_Reinj_1 4534 885 588 Mix4_InSol_Tio2_Reinj_1 4534 P41970 P41970 P41970 >sp|P41970|ELK3_HUMAN ETS domain-containing protein Elk-3 OS=Homo sapiens GN=ELK3 PE=1 SV=2 0.999954 49.3668 0.999655 40.6369 0.111254 40.637 0.999954 49.3668 0.0695367 49.367 1 S SLDRAASPVLLSS CAMK2;CHK1;CHK1/2;PKD;Proline-directed 0.003192 0.0695367 49.367 _AApSPVLLSSNSQKS_ AAS(1)PVLLSSNSQKS AAS(49.37)PVLLS(-49.37)S(-49.37)NS(-49.37)QKS(-49.37) 3 2 734.8558 0.086537 53874 0 0 0 0 0 31244 22630 663 544;545 66;66 66 2360 2670 21842 13573 Mix4_TiO2_1_4 5178 21843 13575 Mix4_TiO2_Reinj_1_4 5527 P42166;P42167;P42167-2 P42166;P42167 P42167 >sp|P42166|LAP2A_HUMAN Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167-2|LAP2B_HUMAN Isoform Gamma of 0.487849 0 0.487849 0 9.26824E-05 93.632 0 0 1.295E-06 -58.8773 1.02746E-11 122.03 0.000761707 -31.1494 0.0203086 63.562 0.170265 -5.86679 0.910148 35.034 1 S KGPPDFSSDEERE CK2 0.117 1.02746E-11 122.03 _GPPDFpSSDEEREPTPVLGSGAAAAGR_ GPPDFS(0.488)S(0.488)DEEREPT(0.024)PVLGSGAAAAGR GPPDFS(0)S(0)DEEREPT(-13.03)PVLGS(-59.29)GAAAAGR 6 3 884.06421 -2.0387 0 0 0 0 0 0 0 0 664 544;545 67;67 67 2360 2670 21842 13573 Mix4_TiO2_1_4 5178 21843 13575 Mix4_TiO2_Reinj_1_4 5527 P42166;P42167;P42167-2 P42166;P42167 P42167 >sp|P42166|LAP2A_HUMAN Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167-2|LAP2B_HUMAN Isoform Gamma of 0.487849 0 0.487849 0 9.26824E-05 93.632 0 0 3.66622E-06 -54.3578 1.02746E-11 122.03 0.00285052 -25.418 0.0203086 63.562 0.170265 -5.86679 0.910148 35.034 1 S GPPDFSSDEEREP CK2 0.117 1.02746E-11 122.03 _GPPDFpSSDEEREPTPVLGSGAAAAGR_ GPPDFS(0.488)S(0.488)DEEREPT(0.024)PVLGSGAAAAGR GPPDFS(0)S(0)DEEREPT(-13.03)PVLGS(-59.29)GAAAAGR 7 3 884.06421 -2.0387 0 0 0 0 0 0 0 0 665 544;545 159;159 159 5762 6565 56656 34571 Mix4_InSol_TiO2_1 5149 56660 34575 Mix4_TiO2_1_4 4140 P42166;P42167;P42167-2 P42166;P42167 P42167 >sp|P42166|LAP2A_HUMAN Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167-2|LAP2B_HUMAN Isoform Gamma of 0.574622 1.70413 0.433928 1.85577 1.0688E-15 157.67 0.399396 0.960239 0.609414 24.872 0.418012 1.57305 3.91714E-06 112.62 0.574622 1.70413 4.55187E-09 131.34 0.413655 1.49515 1.09732E-05 102.74 1 S GTESRSSTPLPTI CK1;PKA 0.042 1.0688E-15 157.67 _SpSTPLPTISSSAENTR_ S(0.388)S(0.575)T(0.037)PLPTISSSAENTR S(-1.7)S(1.7)T(-11.88)PLPT(-75.24)IS(-85.59)S(-104.69)S(-123.77)AENT(-121.52)R 2 2 864.39601 0.12005 396180 0 0 0 0 0 396180 0 666 545 306 306 2559 2907 23978 14869 Mix4_TiO2_Reinj_1_4 8245 23978 14869 Mix4_TiO2_Reinj_1_4 8245 P42167 P42167 P42167 >sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2 1 68.55 0.999992 51.1243 0.00574062 76.766 1 68.55 1.96243E-12 146.64 0 0 0 0 1 S GNFKHASPILPIT Proline-directed 0.05 1.96243E-12 146.64 _HApSPILPITEFSDIPR_ HAS(1)PILPITEFSDIPR HAS(68.55)PILPIT(-68.55)EFS(-125.93)DIPR 3 3 624.98003 -0.38882 672550 96356 0 0 576190 0 0 0 667 547 567 567 2298 2600 21282 13046 Mix4_TiO2_Reinj_1_2 7362 21281 13045 Mix4_TiO2_Reinj_1_1 8135 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.992235 23.8255 0 0 0.992235 23.8255 0.000173641 87.255 0 0 1 S LAHQLASPGLTTL Proline-directed 0.05 0.000173641 87.255 _GLAHQLApSPGLTTLPEASDVGSITLALR_ GLAHQLAS(0.992)PGLT(0.004)T(0.004)LPEASDVGSITLALR GLAHQLAS(23.83)PGLT(-23.83)T(-24.5)LPEAS(-39.85)DVGS(-48.65)IT(-48.35)LALR 8 3 956.83374 0.33475 894850 0 0 0 894850 0 0 0 668 547 1418 1418 2367 2679 21908 13622 Mix4_TiO2_1_1 7491 21908 13622 Mix4_TiO2_1_1 7491 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.995829 23.7816 0.995829 23.7816 0.0462025 57.029 0 0 1 S ILESLISINNKLQ CK1 0.081 0.0462025 57.029 _GPTPAILESLIpSINNK_ GPTPAILES(0.004)LIS(0.996)INNK GPT(-57.03)PAILES(-23.78)LIS(23.78)INNK 12 2 873.95551 0.8892 13108 13108 0 0 0 0 0 0 669 547 2478 2478 3235;6008;6009 3667;6848;6849;6850 59331 36036 Mix4_TiO2_Reinj_1_1 7421 59331 36036 Mix4_TiO2_Reinj_1_1 7421 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.999824 41.2791 0.338539 -2.8117 0.173382 53.045 0 0 0.999824 41.2791 0.000335547 84.651 0 0 0 0 2 S GTTVPESIHSFIG CK1 0.143 0.000335547 84.651 _TGTTVPEpSIHpSFIGDGLVKPEALNK_ TGTTVPES(1)IHS(1)FIGDGLVKPEALNK T(-42.66)GT(-41.28)T(-43.8)VPES(41.28)IHS(43.55)FIGDGLVKPEALNK 8 3 924.10819 -0.017935 232640 0 0 0 232640 0 0 0 670 547 2481 2481 3235;6008;6009 3667;6848;6849;6850 59315 36029 Mix4_TiO2_1_1 6527 30612 19025 Mix4_TiO2_Reinj_1_1 6824 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.943602 15.5178 0.943602 15.5178 0.173382 53.045 0 0 0.859159 7.8536 5.81466E-12 128.7 0 0 0 0 1 S VPESIHSFIGDGL CK1 0.081 5.81466E-12 128.7 _TGTTVPESIHpSFIGDGLVKPEALNK_ T(0.023)GT(0.026)T(0.006)VPESIHS(0.944)FIGDGLVKPEALNK T(-16.06)GT(-15.52)T(-21.91)VPES(-32.97)IHS(15.52)FIGDGLVKPEALNK 11 3 897.45275 0.21855 2369400 553210 0 0 1816200 0 0 0 671 547 2448 2448 5950;6204;6205 6786;6787;7087;7088;7089 58719 35603 Mix4_TiO2_Reinj_1_5 7389 61495 37270 Mix4_TiO2_1_1 5909 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.905316 9.84755 0.834886 8.22103 1.36597E-25 160.21 0.547918 0.861062 0.000152987 90.238 0.905316 9.84755 1.61746E-25 157.31 0 0 0.102317 -5.69445 1.63028 25.351 0.365363 0 0.000169646 89.325 1 S SRTRTDSYSAGQS CAMK2;CK1;PKA/AKT 0.00111111 1.36597E-25 160.21 _TDpSYSAGQSVEILDGVELGEPAHK_ T(0.094)DS(0.905)Y(0.001)SAGQSVEILDGVELGEPAHK T(-9.85)DS(9.85)Y(-31.96)S(-34.25)AGQS(-72.2)VEILDGVELGEPAHK 3 3 861.39345 -0.23481 4694300 909140 92737 0 3692400 0 0 0 672 547 2450 2450 5950;6204;6205 6786;6787;7087;7088;7089 61518 37286 Mix4_TiO2_Reinj_1_1 6470 61518 37286 Mix4_TiO2_Reinj_1_1 6470 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.79249 6.11375 0.299537 0 1.36597E-25 160.21 0.280298 0 0.000152987 90.238 0.79249 6.11375 6.97261E-12 126.96 0 0 0.379658 0.35607 1.63028 25.351 0.180965 -1.40947 0.000169646 89.325 2 S TRTDSYSAGQSVE CK1;GSK3 0.081 6.97261E-12 126.96 _TRTDpSYpSAGQSVEILDGVELGEPAHK_ T(0.076)RT(0.12)DS(0.764)Y(0.041)S(0.792)AGQS(0.206)VEILDGVELGEPAHK T(-10.08)RT(-8.09)DS(8.09)Y(-14.05)S(6.11)AGQS(-6.11)VEILDGVELGEPAHK 7 3 973.76515 -0.021355 537450 0 0 0 537450 0 0 0 673 547 2454 2454 5950;6204;6205 6786;6787;7087;7088;7089 58716 35600 Mix4_TiO2_Reinj_1_1 6639 61495 37270 Mix4_TiO2_1_1 5909 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.996573 24.7062 0.159036 -3.13628 1.36597E-25 160.21 0.135019 -5.60527 0.000152987 90.238 0.996573 24.7062 1.61746E-25 157.31 0 0 0.349772 -0.35607 1.63028 25.351 0.0565497 -6.4611 0.000169646 89.325 1 S SYSAGQSVEILDG CK1 0.143 1.36597E-25 160.21 _TDSYSAGQpSVEILDGVELGEPAHK_ TDSYS(0.003)AGQS(0.997)VEILDGVELGEPAHK T(-60.65)DS(-59.51)Y(-42.74)S(-24.71)AGQS(24.71)VEILDGVELGEPAHK 9 3 861.39345 -0.047152 363170 0 0 0 363170 0 0 0 674 548 1421 1421 3240 3672 30637 19034 Mix4_TiO2_Reinj_1_5 1303 30637 19034 Mix4_TiO2_Reinj_1_5 1303 P42356;P42356-2 P42356 P42356 >sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA PE=1 SV=3;>sp|P42356-2|PI4KA_HUMAN Isoform PI4K97 of Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA 0.974445 15.8128 0 0 0 0 0.974445 15.8128 0.100775 38.008 1 S KKTNRGSQLHKYY CK1;PKA 0.042 0.100775 38.008 _KTNRGpSQLHK_ KT(0.026)NRGS(0.974)QLHK KT(-15.81)NRGS(15.81)QLHK 6 2 624.81407 -0.057709 187610 0 0 0 187610 0 0 0 675 548 198 198 3245;6249 3679;7139 30685 19058 Mix4_TiO2_1_5 3565 30684 19057 Mix4_TiO2_1_1 3179 P42356 P42356 P42356 >sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA PE=1 SV=3 0.931923 13.268 0.931923 13.268 6.4707E-07 119.73 0 0 0.569816 1.85842 5.48238E-05 106.92 0.54028 1.45912 0.00729942 75.842 0 0 1 S TLKRKTSSVSSIS CAMK2;CHK1;CHK1/2;GSK3;PKA;PKD 0.003024 6.4707E-07 119.73 _KTpSSVSSISQVSPER_ KT(0.024)S(0.932)S(0.044)VSSISQVSPER KT(-15.93)S(13.27)S(-13.27)VS(-38.24)S(-40.08)IS(-38.92)QVS(-76.44)PER 3 2 836.4011 0.20584 260310 80003 0 0 125760 0 54548 0 676 548 199 199 3245;6249 3679;7139 30687 19060 Mix4_TiO2_Reinj_1_1 3685 30684 19057 Mix4_TiO2_1_1 3179 P42356 P42356 P42356 >sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA PE=1 SV=3 0.536658 1.42152 0.449481 0.393326 6.4707E-07 119.73 0 0 0.536658 1.42152 5.48238E-05 106.92 0.0601242 -9.5357 0.00729942 75.842 0 0 1 S LKRKTSSVSSISQ 6.4707E-07 119.73 _KTSpSVSSISQVSPER_ KT(0.072)S(0.387)S(0.537)VS(0.001)S(0.004)ISQVSPER KT(-8.72)S(-1.42)S(1.42)VS(-28.69)S(-21.71)IS(-35.54)QVS(-71.9)PER 4 2 836.4011 0.15728 136790 0 0 0 136790 0 0 0 677 548 207 207 3245;6249 3679;7139 62006 37558 Mix4_TiO2_Reinj_1_1 3598 30684 19057 Mix4_TiO2_1_1 3179 P42356 P42356 P42356 >sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA PE=1 SV=3 0.999363 31.9692 0.9868 24.1548 6.4707E-07 119.73 0 0 0.999363 31.9692 5.48238E-05 106.92 1.40744E-08 -75.8419 0.00729942 75.842 0 0 1 S SSISQVSPERGMP CDK1;CDK2;CK1;Proline-directed 0.0057 6.4707E-07 119.73 _TSSVSSISQVpSPER_ TSSVSSIS(0.001)QVS(0.999)PER T(-82.71)S(-82.71)S(-82.71)VS(-79.55)S(-56.32)IS(-31.97)QVS(31.97)PER 11 2 772.35362 0.43149 465020 22864 0 0 442150 0 0 0 678 550 11 11 1012 1136 9651 5894 Mix4_InSol_Tio2_Reinj_1 4509 9650 5893 Mix4_InSol_TiO2_1 4555 P42677 P42677 P42677 >sp|P42677|RS27_HUMAN 40S ribosomal protein S27 OS=Homo sapiens GN=RPS27 PE=1 SV=3 1 30.4253 1 47.1286 0.0691976 47.129 1 30.4253 0.260799 30.425 1 S KDLLHPSPEEEKR CK2;NEK6;Proline-directed 0.05 0.0691976 47.129 _DLLHPpSPEEEKRK_ DLLHPS(1)PEEEKRK DLLHPS(30.43)PEEEKRK 6 3 553.26969 0.34598 121880 0 0 0 0 0 59393 62488 679 552 1051 1051 243 280 2452 1552 Mix4_TiO2_1_5 5141 2453 1554 Mix4_TiO2_Reinj_1_5 5921 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.261085 0 0.261085 0 0.0882661 54.011 0.25 0 0.0142496 64.129 1 S QVPLPTSSISPAK NEK6 0.076 0.0142496 64.129 _AGRPVM(ox)PPPQVPLPpTSSISPAK_ AGRPVMPPPQVPLPT(0.261)S(0.261)S(0.261)IS(0.217)PAK AGRPVMPPPQVPLPT(0)S(0)S(0)IS(-0.81)PAK 16 3 775.06751 0.10059 0 0 0 0 0 0 0 0 680 552 1052 1052 243 280 2452 1552 Mix4_TiO2_1_5 5141 2453 1554 Mix4_TiO2_Reinj_1_5 5921 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.261085 0 0.261085 0 0.0882661 54.011 0.25 0 0.0142496 64.129 1 S VPLPTSSISPAKM 0.0142496 64.129 _AGRPVM(ox)PPPQVPLPpTSSISPAK_ AGRPVMPPPQVPLPT(0.261)S(0.261)S(0.261)IS(0.217)PAK AGRPVMPPPQVPLPT(0)S(0)S(0)IS(-0.81)PAK 17 3 775.06751 0.10059 0 0 0 0 0 0 0 0 681 552 1054 1054 243 280 2453 1554 Mix4_TiO2_Reinj_1_5 5921 2453 1554 Mix4_TiO2_Reinj_1_5 5921 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.25 0 0.216746 -0.808299 0.0882661 54.011 0.25 0 0.0142496 64.129 1 S LPTSSISPAKMAN CDK1;CDK2;CK1;Proline-directed 0.0057 0.0142496 64.129 _AGRPVM(ox)PPPQVPLPpTSSISPAK_ AGRPVMPPPQVPLPT(0.25)S(0.25)S(0.25)IS(0.25)PAK AGRPVMPPPQVPLPT(0)S(0)S(0)IS(0)PAK 19 3 775.06751 -0.096905 0 0 0 0 0 0 0 0 682 552 631 631 959;960 1081;1082 9180 5630 Mix4_InSol_Tio2_Reinj_2 5153 9183 5635 Mix4_TiO2_1_5 5848 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.999685 38.0209 0.999514 33.7411 2.302E-15 143.6 0.975578 16.3485 0.0459435 52.096 0.99665 25.2345 5.47376E-10 125.58 0.856404 8.86888 0.385289 18.978 0.996805 27.9513 3.91419E-06 107.13 0.999685 38.0209 4.40431E-05 98.372 1 S RKQRDKSPSSLLE CAMK2;Proline-directed 0.042 2.302E-15 143.6 _DKpSPSSLLEDAKETCFTR_ DKS(1)PSSLLEDAKETCFTR DKS(38.02)PS(-38.02)S(-38.02)LLEDAKET(-72.13)CFT(-72.13)R 3 3 721.99245 -0.24626 24915000 4954200 60826 0 14474000 21010 2916100 2488700 683 552 633 633 959;960 1081;1082 9153 5618 Mix4_TiO2_Reinj_1_5 5284 9183 5635 Mix4_TiO2_1_5 5848 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.889044 9.0436 0.499964 0 2.302E-15 143.6 0.0226161 -16.3485 0.0459435 52.096 0.889044 9.0436 5.47376E-10 125.58 0.11112 -8.86888 0.385289 18.978 0.293547 0.893492 3.91419E-06 107.13 0.199595 -5.99778 4.40431E-05 98.372 1 S QRDKSPSSLLEDA 2.302E-15 143.6 _DKSPpSSLLEDAK_ DKS(0.111)PS(0.889)SLLEDAK DKS(-9.04)PS(9.04)S(-37.73)LLEDAK 5 3 457.21307 -0.23507 448880 89327 0 0 359550 0 0 0 684 552 602 602 1699;4773 1909;5421 15519 9359 Mix4_TiO2_Reinj_1_5 6816 15515 9355 Mix4_TiO2_1_5 5964 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.996682 24.7888 0.995951 23.9134 1.87631E-33 188.76 0.233206 -2.92324 1.7964 10.143 0.996682 24.7888 4.43988E-25 172.18 0.794096 6.83462 1.40367E-07 105.3 0 0 1 S QDATENSASSLAP 1.87631E-33 188.76 _ENIEGAQDATENpSASSLAPGFIR_ ENIEGAQDATENS(0.997)AS(0.003)SLAPGFIR ENIEGAQDAT(-51.23)ENS(24.79)AS(-24.79)S(-59.41)LAPGFIR 13 3 819.7025 0.36242 2931800 0.70552 562830 0 0 1975200 0 393770 0 685 552 604 604 1699;4773 1909;5421 15517 9357 Mix4_TiO2_2_2 7612 15515 9355 Mix4_TiO2_1_5 5964 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.457156 2.92324 0.0383582 -13.9796 1.87631E-33 188.76 0.457156 2.92324 1.7964 10.143 0.125379 -8.39107 4.43988E-25 172.18 0.164593 -6.83462 1.40367E-07 105.3 0 0 1 S ATENSASSLAPGF 1.87631E-33 188.76 _ENIEGAQDATENSApSSLAPGFIR_ ENIEGAQDAT(0.174)ENS(0.233)AS(0.457)S(0.136)LAPGFIR ENIEGAQDAT(-4.2)ENS(-2.92)AS(2.92)S(-5.27)LAPGFIR 15 2 1229.0501 -1.4466 0 0 0 0 0 0 0 0 0 686 552 617 617 2114;2115 2398;2399 19518 11908 Mix4_InSol_TiO2_2 2170 19488 11860 Mix4_InSol_TiO2_1 3725 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.457188 0.728442 0.000190452 -37.1986 0.000311311 109.15 0.0950532 -9.06468 0.00223159 91.221 1.87766E-06 -57.2633 3.54002E-05 124.74 0.193811 -4.99641 0.0836415 43.204 0.457188 0.728442 2.24738E-05 130.21 0.040088 -13.6069 0.000311311 109.15 1 S IRGAQASSGSPAL 2.24738E-05 130.21 _GAQApSSGSPALPRK_ GAQAS(0.457)S(0.387)GS(0.156)PALPRK GAQAS(0.73)S(-0.73)GS(-4.66)PALPRK 5 2 703.84302 -0.25971 0 0 0 0 0 0 0 0 687 552 618 618 2114;2115 2398;2399 19517 11907 Mix4_InSol_TiO2_1 3077 19488 11860 Mix4_InSol_TiO2_1 3725 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.558268 1.15654 0.026416 -15.6647 0.000311311 109.15 0.138584 -7.42723 0.00223159 91.221 0.000117337 -39.3051 3.54002E-05 124.74 0.193811 -4.99641 0.0836415 43.204 0.558268 1.15654 2.24738E-05 130.21 0.170562 -6.74852 0.000311311 109.15 1 S RGAQASSGSPALP 2.24738E-05 130.21 _GAQASpSGSPALPRK_ GAQAS(0.014)S(0.558)GS(0.428)PALPRK GAQAS(-16.01)S(1.16)GS(-1.16)PALPRK 6 3 469.56444 -0.57612 142180 0 0 0 0 0 142180 0 688 552 620 620 2114;2115 2398;2399 19488 11860 Mix4_InSol_TiO2_1 3725 19488 11860 Mix4_InSol_TiO2_1 3725 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.999999 59.8603 0.999992 51.6309 0.000311311 109.15 0.999572 33.7059 0.00223159 91.221 0.999998 57.5135 3.54002E-05 124.74 0.999373 32.9377 0.0836415 43.204 0.999999 59.8603 2.24738E-05 130.21 0.999998 57.4188 0.000311311 109.15 1 S AQASSGSPALPRK CK1;Proline-directed 0.05 2.24738E-05 130.21 _GAQASSGpSPALPR_ GAQASSGS(1)PALPR GAQAS(-77.95)S(-59.86)GS(59.86)PALPR 8 2 639.79554 0.21891 21015000 2844400 104050 0 11199000 34885 4215000 2617700 689 552 915 915 3455 3900;3901 32559 20194 Mix4_TiO2_Reinj_1_5 5776 32559 20194 Mix4_TiO2_Reinj_1_5 5776 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 1 83.6809 0 0 1 83.6809 0.000551453 83.681 1 49.9014 0.109939 49.901 1 52.2462 0.0892171 52.246 1 S EQPGWPSPAKAAP CDK1;CDK2;Proline-directed 0.0057 0.000551453 83.681 _LGM(ox)AGVPEDGEQPGWPpSPAK_ LGMAGVPEDGEQPGWPS(1)PAK LGMAGVPEDGEQPGWPS(83.68)PAK 17 2 1059.9637 0.30734 306410 0 0 0 151570 0 79795 75043 690 552 781 781 5530 6298;6299 54101 33119 Mix4_InSol_TiO2_1 4460 54101 33119 Mix4_InSol_TiO2_1 4460 P42684;P42684-3;P42684-2 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.989624 20.2845 0 0 0 0 0.370129 -1.8924 3.42094E-12 139.16 0.989624 20.2845 5.82983E-16 165.97 0.47954 0 6.05756E-06 109.62 1 S SKPFPRSNSTSSM GSK3 0.081 5.82983E-16 165.97 _pSNSTSSMSSGLPEQDR_ S(0.99)NS(0.009)T(0.001)SSMSSGLPEQDR S(20.28)NS(-20.28)T(-30.35)S(-37.06)S(-63.8)MS(-97.43)S(-104.57)GLPEQDR 1 2 881.85111 0.3958 151450 0 0 0 0 0 151450 0 691 552 783 783 5530 6298;6299 54109 33123 Mix4_TiO2_Reinj_1_5 3244 54101 33119 Mix4_InSol_TiO2_1 4460 P42684;P42684-3;P42684-2 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.572259 1.8924 0 0 0 0 0.572259 1.8924 3.42094E-12 139.16 0.221668 0 5.82983E-16 165.97 0.47954 0 6.05756E-06 109.62 1 S PFPRSNSTSSMSS CAMK2;PKA/AKT 0.00111111 5.82983E-16 165.97 _SNpSTSSM(ox)SSGLPEQDR_ S(0.37)NS(0.572)T(0.057)S(0.001)SMSSGLPEQDR S(-1.89)NS(1.89)T(-10.04)S(-27.82)S(-45.02)MS(-80.76)S(-87.89)GLPEQDR 3 2 889.84857 -0.36974 323990 0 0 0 323990 0 0 0 692 552 817 817 6299 7197;7199 62998 38376 Mix4_TiO2_1_6 2121 63001 38380 Mix4_TiO2_Reinj_1_5 3230 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.953175 15.7599 0.953175 15.7599 1.64222E-06 120.21 0.540101 1.28649 0.0286081 59.088 0.899971 10.491 9.83691E-09 140.79 0 0 0.494098 0 0.000179347 102.71 0.0023959 -25.6556 0.00633133 76.759 1 S QLERTVSTSSQPE CAMK2;CHK1;CHK1/2;PKA/AKT;PKD 0.00111111 9.83691E-09 140.79 _TVpSTSSQPEENVDR_ T(0.02)VS(0.953)T(0.025)S(0.001)SQPEENVDR T(-16.78)VS(15.76)T(-15.76)S(-29.63)S(-33)QPEENVDR 3 2 814.84361 0.75911 2360800 2.6673 635650 18929 0 1706200 0 0 0 693 552 819 819 6299 7197;7199 63000 38378 Mix4_TiO2_Reinj_1_1 2725 63001 38380 Mix4_TiO2_Reinj_1_5 3230 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.516521 0.932741 0.0747083 -7.9939 1.64222E-06 120.21 0.000910101 -27.7339 0.0286081 59.088 0.516521 0.932741 9.83691E-09 140.79 0 0 0.000894653 -27.4216 0.000179347 102.71 0.10108 -9.40361 0.00633133 76.759 1 S ERTVSTSSQPEEN CK1 0.143 9.83691E-09 140.79 _TVSTpSSQPEENVDR_ TVS(0.007)T(0.06)S(0.517)S(0.417)QPEENVDR T(-49.35)VS(-18.62)T(-9.37)S(0.93)S(-0.93)QPEENVDR 5 2 814.84361 0.1148 62603 0.070733 0 0 0 62603 0 0 0 694 552 820 820 6299 7197;7199 62995 38371 Mix4_InSol_Tio2_Reinj_1 3345 63001 38380 Mix4_TiO2_Reinj_1_5 3230 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.881103 9.40361 0.989415 19.7297 1.32713E-06 123.53 0.0001578 -35.3437 0.0286081 59.088 0.986184 18.5433 4.2134E-08 137.05 0 0 2.0831E-05 -43.751 0.000179347 102.71 0.881103 9.40361 0.00633133 76.759 1 S RTVSTSSQPEENV CK1;CK2 0.081 9.83691E-09 140.79 _TVSTSpSQPEENVDR_ TVS(0.002)T(0.015)S(0.101)S(0.881)QPEENVDR T(-54.37)VS(-25.66)T(-17.57)S(-9.4)S(9.4)QPEENVDR 6 2 814.84361 0.72473 94960 0.10729 0 0 0 0 0 0 94960 695 552 936 936 6547 7490 66128 40597 Mix4_TiO2_2_2 5432 66134 40608 Mix4_TiO2_Reinj_1_5 6642 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.999965 44.5024 0.999914 40.6566 0.00163617 96.153 0.999965 44.5024 0.00407196 111.57 0.999007 30.0252 0.00407197 111.57 0.902893 9.68386 0.000910053 79.049 0.993469 21.8215 0.0633765 41.572 0.991172 20.5028 0.0633765 41.572 1 S KVPVLISPTLKHT Proline-directed 0.05 0.00407197 111.57 _VPVLIpSPTLK_ VPVLIS(1)PTLK VPVLIS(44.5)PT(-44.5)LK 6 2 573.83033 -0.33604 6683000 1282600 879010 0 4371100 18564 63224 68571 696 554 1763 1763 4921 5595 47235 28850 Mix4_InSol_TiO2_1 5416 47236 28851 Mix4_InSol_Tio2_Reinj_1 5355 P42694 P42694 P42694 >sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2 0.43502 0 0 0 0 0 0.43502 0 1.44678E-07 113.52 0.100896 -6.74182 1.96589E-18 153.64 1 S LYQRRISSSSVQP CAMK2;PKA;PKA/AKT 0.00111111 1.96589E-18 153.64 _RIpSSSSVQPCSEEVSTPQDSLAQCK_ RIS(0.435)S(0.435)S(0.111)S(0.019)VQPCSEEVSTPQDSLAQCK RIS(0)S(0)S(-5.92)S(-13.66)VQPCS(-61.51)EEVS(-99.19)T(-105.6)PQDS(-113.52)LAQCK 3 3 954.08781 0.13834 0 0 0 0 0 0 0 0 697 554 1764 1764 4921 5595 47235 28850 Mix4_InSol_TiO2_1 5416 47236 28851 Mix4_InSol_Tio2_Reinj_1 5355 P42694 P42694 P42694 >sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2 0.43502 0 0 0 0 0 0.43502 0 1.44678E-07 113.52 0.161485 -4.69925 1.96589E-18 153.64 1 S YQRRISSSSVQPC CAMK2 0.042 1.96589E-18 153.64 _RIpSSSSVQPCSEEVSTPQDSLAQCK_ RIS(0.435)S(0.435)S(0.111)S(0.019)VQPCSEEVSTPQDSLAQCK RIS(0)S(0)S(-5.92)S(-13.66)VQPCS(-61.51)EEVS(-99.19)T(-105.6)PQDS(-113.52)LAQCK 4 3 954.08781 0.13834 0 0 0 0 0 0 0 0 698 554 1766 1766 4921 5595 47236 28851 Mix4_InSol_Tio2_Reinj_1 5355 47236 28851 Mix4_InSol_Tio2_Reinj_1 5355 P42694 P42694 P42694 >sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS=Homo sapiens GN=HELZ PE=1 SV=2 0.476494 2.61221 0 0 0 0 0.0187309 -13.6595 1.44678E-07 113.52 0.476494 2.61221 1.96589E-18 153.64 1 S RRISSSSVQPCSE CK1 0.081 1.96589E-18 153.64 _RISSSpSVQPCSEEVSTPQDSLAQCK_ RIS(0.101)S(0.161)S(0.261)S(0.476)VQPCSEEVSTPQDSLAQCK RIS(-6.74)S(-4.7)S(-2.61)S(2.61)VQPCS(-48.25)EEVS(-99.86)T(-120.85)PQDS(-153.64)LAQCK 6 3 954.08781 -0.23304 0 0 0 0 0 0 0 0 699 555 1382 1382 5443 6194 53086 32451 Mix4_TiO2_Reinj_1_1 7765 53087 32452 Mix4_TiO2_Reinj_1_5 8176 P42695 P42695 P42695 >sp|P42695|CNDD3_HUMAN Condensin-2 complex subunit D3 OS=Homo sapiens GN=NCAPD3 PE=1 SV=2 0.575339 1.33449 0.499748 0 1.56778E-12 148.64 0 0 0.575339 1.33449 7.31286E-20 180.08 1 S LPFTLNSGSPEKT 7.31286E-20 180.08 _SLGVLPFTLNpSGSPEK_ SLGVLPFT(0.002)LNS(0.575)GS(0.423)PEK S(-96.57)LGVLPFT(-25.75)LNS(1.33)GS(-1.33)PEK 11 2 863.42659 0.026667 146380 0 0 0 146380 0 0 0 700 555 1384 1384 5443 6194 53085 32450 Mix4_TiO2_1_5 7355 53087 32452 Mix4_TiO2_Reinj_1_5 8176 P42695 P42695 P42695 >sp|P42695|CNDD3_HUMAN Condensin-2 complex subunit D3 OS=Homo sapiens GN=NCAPD3 PE=1 SV=2 0.999174 30.8294 0.999174 30.8294 1.56778E-12 148.64 0 0 0.998997 29.9827 7.31286E-20 180.08 1 S FTLNSGSPEKTCS CDK1;CDK2;Proline-directed 0.0057 7.31286E-20 180.08 _SLGVLPFTLNSGpSPEK_ SLGVLPFTLNS(0.001)GS(0.999)PEK S(-148.64)LGVLPFT(-67.75)LNS(-30.83)GS(30.83)PEK 13 2 863.42659 0.31681 633290 179140 0 0 454150 0 0 0 701 557 1199 1199 1613;2292 1811;2593 14851 9005 Mix4_TiO2_1_1 3075 14851 9005 Mix4_TiO2_1_1 3075 P42858 P42858 P42858 >sp|P42858|HD_HUMAN Huntingtin OS=Homo sapiens GN=HTT PE=1 SV=2 1 79.4282 1 79.4282 3.67632E-09 140.98 0 0 0.957248 13.5007 0.0853323 51.414 0 0 0.99999 50.2186 0.00392621 77.911 0.999965 44.5202 0.112238 44.52 1 S QASVPLSPKKGSE CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.67632E-09 140.98 _EKEPGEQASVPLpSPK_ EKEPGEQASVPLS(1)PK EKEPGEQAS(-79.43)VPLS(79.43)PK 13 2 838.40057 -0.25568 1149400 409630 0 0 561490 0 153400 24874 702 557 1874 1874 3578 4033 33706 20772 Mix4_InSol_TiO2_1 6063 33706 20772 Mix4_InSol_TiO2_1 6063 P42858 P42858 P42858 >sp|P42858|HD_HUMAN Huntingtin OS=Homo sapiens GN=HTT PE=1 SV=2 1 67.3888 0.999997 55.1632 7.97762E-10 120.17 0 0 0.999999 59.3351 4.11821E-10 128.48 1 67.3888 4.32954E-16 154.22 0.99992 41.1308 0.0147271 67.929 1 S LLSPQMSGEEEDS CK1;CK2 0.117 4.32954E-16 154.22 _LLSPQMpSGEEEDSDLAAK_ LLSPQMS(1)GEEEDSDLAAK LLS(-67.39)PQMS(67.39)GEEEDS(-80.85)DLAAK 7 2 1000.4319 0.84049 505700 54173 0 0 218950 0 130710 101870 703 557 417 417 5325 6061;6062 51700 31663 Mix4_TiO2_Reinj_1_1 7229 51698 31661 Mix4_TiO2_1_1 6652 P42858 P42858 P42858 >sp|P42858|HD_HUMAN Huntingtin OS=Homo sapiens GN=HTT PE=1 SV=2 0.487027 0 0.373672 -2.24142 5.85337E-11 123.02 0.00449406 -21.928 1.14237 21.928 0.487027 0 6.38289E-11 121.74 0 0 0 0 2 S SGGRSRSGSIVEL CAMK2;PKA/AKT 0.00111111 5.85337E-11 123.02 _pSGSIVELIAGGGSSCpSPVLSR_ S(0.487)GS(0.513)IVELIAGGGS(0.014)S(0.118)CS(0.866)PVLS(0.001)R S(0)GS(0)IVELIAGGGS(-17.09)S(-7.88)CS(7.88)PVLS(-26.99)R 1 3 731.66013 -0.058523 0 0 0 0 0 0 0 0 704 557 419 419 5325 6061;6062 51699 31662 Mix4_TiO2_Reinj_1_1 7207 51698 31661 Mix4_TiO2_1_1 6652 P42858 P42858 P42858 >sp|P42858|HD_HUMAN Huntingtin OS=Homo sapiens GN=HTT PE=1 SV=2 0.643933 2.60285 0.626328 2.24142 5.85337E-11 123.02 0.00449406 -21.928 1.14237 21.928 0.643933 2.60285 6.38289E-11 121.74 0 0 0 0 2 S GRSRSGSIVELIA CAMK2;CK1;CK2;PKA/AKT 0.001764 5.85337E-11 123.02 _SGpSIVELIAGGGSSCpSPVLSR_ S(0.356)GS(0.644)IVELIAGGGS(0.003)S(0.011)CS(0.754)PVLS(0.233)R S(-2.6)GS(2.6)IVELIAGGGS(-24.28)S(-18.58)CS(5.15)PVLS(-5.15)R 3 2 1096.9866 0.1669 855750 99526 0 0 756230 0 0 0 705 557 432 432 5325 6061;6062 51706 31666 Mix4_TiO2_Reinj_1_1 7528 51704 31664 Mix4_TiO2_1_1 6773 P42858 P42858 P42858 >sp|P42858|HD_HUMAN Huntingtin OS=Homo sapiens GN=HTT PE=1 SV=2 0.999216 31.1541 0.829195 6.94302 2.22834E-39 211.68 0.700546 4.80201 1.14237 21.928 0.999216 31.1541 3.03624E-32 180.61 0 0 0 0 1 S GGGSSCSPVLSRK CK1;GSK3;Proline-directed 0.05 2.22834E-39 211.68 _SGSIVELIAGGGSSCpSPVLSR_ SGSIVELIAGGGSS(0.001)CS(0.999)PVLSR S(-169.99)GS(-169.99)IVELIAGGGS(-59.38)S(-31.15)CS(31.15)PVLS(-47.77)R 16 3 705.00469 -0.54611 681500 99836 6240.7 0 575430 0 0 0 706 558 188 188 4835;4836 5489;5490 46167 28228 Mix4_TiO2_Reinj_1_5 2555 46176 28236 Mix4_TiO2_Reinj_1_5 6260 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 1 33.8364 1 2.59103 0.620134 34.028 0.833761 7.03962 0.592937 34.543 1 33.8364 9.17129E-08 116.3 0 0 0 0 0 0 1 S RHFRRDSFDDRGP AURORA;AURORA-A;CAMK2;CK2;PKA 0.004788 9.17129E-08 116.3 _RDpSFDDR_ RDS(1)FDDR RDS(33.84)FDDR 3 2 495.68747 0.58127 3358100 60290 33181 0 3264600 0 0 0 707 558 195 195 4836 5490 46175 28235 Mix4_TiO2_Reinj_1_5 6247 46176 28236 Mix4_TiO2_Reinj_1_5 6260 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 0.995842 23.7934 0.160955 -6.57612 0.620134 34.028 0.164847 -7.03962 0.592937 34.543 0.995842 23.7934 9.17129E-08 116.3 0 0 0 0 0 0 1 S FDDRGPSLNPVLD CAMK2 0.042 9.17129E-08 116.3 _RDSFDDRGPpSLNPVLDYDHGSR_ RDS(0.004)FDDRGPS(0.996)LNPVLDYDHGSR RDS(-23.79)FDDRGPS(23.79)LNPVLDY(-78.53)DHGS(-78.53)R 10 4 650.28968 -0.04534 2133900 0 0 0 2133900 0 0 0 708 558 596 596 5877;5878 6702;6703;6704 57961 35219 Mix4_TiO2_Reinj_1_5 2120 57958 35215 Mix4_InSol_TiO2_1 2261 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 0.828139 6.87054 0.0841725 -10.2421 0.000235909 111.74 0 0 0.828139 6.87054 0.00016937 103.58 0.0974339 -9.66528 0.000540921 96.891 0.428638 -1.24969 0.0370529 57.082 2 S DKSRKRSYSPDGK CAMK2;CK1;PKA 0.004788 7.09412E-07 130.03 _pSYSPDGKEpSPSDKK_ S(0.828)Y(0.002)S(0.17)PDGKES(0.986)PS(0.014)DKK S(6.87)Y(-27.35)S(-6.87)PDGKES(18.36)PS(-18.36)DKK 1 2 842.82879 0.13342 367840 0 0 0 367840 0 0 0 709 558 598 598 5877;5878 6702;6703;6704 57979 35238 Mix4_TiO2_Reinj_1_5 2239 57954 35213 Mix4_TiO2_1_5 1935 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 0.999374 32.4541 0.992445 21.1867 0.000235909 111.74 0 0 0.999374 32.4541 0.00128531 92.396 0.980457 17.5921 0.000540921 96.891 0.995401 26.6152 0.0228003 61.162 1 S SRKRSYSPDGKES CAMK2;PKA;PKA/AKT;Proline-directed 0.001764 0.000235909 111.74 _SYpSPDGKESPSDKK_ SY(0.001)S(0.999)PDGKESPSDKK S(-42.58)Y(-32.45)S(32.45)PDGKES(-56.01)PS(-87.28)DKK 3 3 535.56618 0.47572 5059600 328710 0 0 2255600 0 1224500 1250800 710 558 604 604 5877;5878 6702;6703;6704 57958 35215 Mix4_InSol_TiO2_1 2261 57958 35215 Mix4_InSol_TiO2_1 2261 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 0.985555 18.3822 0.980329 17.0314 0.0020683 87.668 0 0 0.985537 18.3645 0.00016937 103.58 0.985555 18.3822 7.09412E-07 130.03 0.921044 10.794 0.0370529 57.082 2 S SPDGKESPSDKKS CK2;Proline-directed 0.05 7.09412E-07 130.03 _SYpSPDGKEpSPSDKK_ S(0.058)Y(0.002)S(0.94)PDGKES(0.986)PS(0.014)DKK S(-12.08)Y(-27.3)S(12.08)PDGKES(18.38)PS(-18.38)DKK 9 2 842.82879 -0.074319 793280 99976 0 0 367840 0 159400 166070 711 558 606 606 5877;5878 6702;6703;6704 57962 35220 Mix4_TiO2_Reinj_1_5 2124 57958 35215 Mix4_InSol_TiO2_1 2261 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 0.470376 0 0.0196712 -17.0314 0.0020683 87.668 0 0 0.470376 0 0.00016937 103.58 0.0144449 -18.3822 7.09412E-07 130.03 0.123206 -3.29937 0.0228003 61.162 2 S DGKESPSDKKSKT GSK3 0.081 7.09412E-07 130.03 _SYpSPDGKEpSPSDKK_ S(0.118)Y(0.118)S(0.822)PDGKES(0.47)PS(0.47)DKK S(-11.1)Y(-11.1)S(11.1)PDGKES(0)PS(0)DKK 11 3 562.22162 0.15615 0 0 0 0 0 0 0 0 712 559 281 281 438 500 4132 2473 Mix4_InSol_TiO2_1 1532 4133 2474 Mix4_InSol_Tio2_Reinj_1 1614 P43307;P43307-2 P43307 P43307 >sp|P43307|SSRA_HUMAN Translocon-associated protein subunit alpha OS=Homo sapiens GN=SSR1 PE=1 SV=3;>sp|P43307-2|SSRA_HUMAN Isoform 2 of Translocon-associated protein subunit alpha OS=Homo sapiens GN=SSR1 0.999999 61.3933 0 0 0.999999 61.3933 0.00663528 61.393 0.999998 56.9712 0.00578274 64.022 1 S KRAQKRSVGSDE_ AURORA;AURORA-1 0.020748 0.00578274 64.022 _AQKRpSVGSDE_ AQKRS(1)VGSDE AQKRS(61.39)VGS(-61.39)DE 5 2 578.75334 0.61073 186150 0 0 0 0 0 78301 107850 713 559 268 268 6389 7310 64571 39609 Mix4_TiO2_Reinj_1_2 6236 64571 39609 Mix4_TiO2_Reinj_1_2 6236 P43307;P43307-2 P43307 P43307 >sp|P43307|SSRA_HUMAN Translocon-associated protein subunit alpha OS=Homo sapiens GN=SSR1 PE=1 SV=3;>sp|P43307-2|SSRA_HUMAN Isoform 2 of Translocon-associated protein subunit alpha OS=Homo sapiens GN=SSR1 0.934544 11.5468 0.0741707 -10.8761 1.83651 22.967 0.934544 11.5468 0.0431437 60.502 1 S NQINKASPRRLPR CDK1;CDK2;Proline-directed 0.0057 0.0431437 60.502 _VEM(ox)GTSSQNDVDM(ox)SWIPQETLNQINKApSPR_ VEMGTSSQNDVDMSWIPQET(0.065)LNQINKAS(0.935)PR VEMGT(-60.5)S(-60.5)S(-60.5)QNDVDMS(-58.16)WIPQET(-11.55)LNQINKAS(11.55)PR 28 3 1163.1884 -1.3076 250470 0 0 0 250470 0 0 0 714 563 115 115 3763;3764 4247;4248 35585 21982 Mix4_TiO2_1_2 4718 35589 21989 Mix4_TiO2_Reinj_1_2 5639 P45880;P45880-1;P45880-2 P45880 P45880 >sp|P45880|VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2 PE=1 SV=2;>sp|P45880-1|VDAC2_HUMAN Isoform 1 of Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2;>sp|P45880-2|VDAC2_HUMAN Isofor 0.999907 40.4294 0.999907 40.4294 8.01356E-09 158.97 0.873607 8.45384 0.07179 46.424 0.993822 23.1868 9.1341E-14 189.65 0.999329 33.0956 2.03911E-06 149.58 0.937439 12.7731 0.00883678 74.641 1 S TFDTTFSPNTGKK Proline-directed 0.05 9.1341E-14 189.65 _LTFDTTFpSPNTGK_ LTFDTTFS(1)PNTGK LT(-122.39)FDT(-67.82)T(-40.43)FS(40.43)PNT(-57.4)GK 8 2 754.83707 -0.12238 8560300 2563900 25935 0 5531100 0 347610 91749 715 564 377 377 2386 2702 22202 13848 Mix4_TiO2_Reinj_1_4 4404 22202 13848 Mix4_TiO2_Reinj_1_4 4404 P45983-2;P45983-3 P45983-2 P45983-2 >sp|P45983-2|MK08_HUMAN Isoform JNK1-alpha-1 of Mitogen-activated protein kinase 8 OS=Homo sapiens GN=MAPK8;>sp|P45983-3|MK08_HUMAN Isoform JNK1-beta-1 of Mitogen-activated protein kinase 8 OS=Homo sapiens GN=MAPK8 1 136.89 1 18.2453 0.00226838 124.82 0 0 1 136.89 0.000314747 136.89 1 19.4834 0.00274607 121.87 1 86.1257 0.00245619 86.126 1 S VIRGQPSPLAQVQ Proline-directed 0.05 0.000314747 136.89 _GQPpSPLAQVQQ_ GQPS(1)PLAQVQQ GQPS(136.89)PLAQVQQ 4 2 616.78718 0.13139 5374400 2.3667 1067600 0 0 3198400 0 621440 486930 716 566 584 584 454 516 4213 2522 Mix4_InSol_Tio2_Reinj_1 5934 4214 2523 Mix4_TiO2_1_1 4469 P46013;P46013-2 P46013 P46013 >sp|P46013|KI67_HUMAN Antigen KI-67 OS=Homo sapiens GN=MKI67 PE=1 SV=2;>sp|P46013-2|KI67_HUMAN Isoform Short of Antigen KI-67 OS=Homo sapiens GN=MKI67 0.999962 44.2718 0.996075 24.0444 0.00333192 80.038 0 0 0.997125 25.4758 0.0960056 43.08 0.999337 31.8112 0.0527181 53.385 0.999962 44.2718 0.0221202 61.805 1 S ISPPAPSPRKTPV CDK1;CDK2;Proline-directed 0.0057 0.00333192 80.038 _AQSLVISPPAPpSPR_ AQSLVISPPAPS(1)PR AQS(-61.81)LVIS(-44.27)PPAPS(44.27)PR 12 2 750.38452 -0.094315 383230 39561 0 0 172000 0 87800 83869 717 566 357 357 6165 7039 61098 37014 Mix4_TiO2_1_5 2384 61098 37014 Mix4_TiO2_1_5 2384 P46013 P46013 P46013 >sp|P46013|KI67_HUMAN Antigen KI-67 OS=Homo sapiens GN=MKI67 PE=1 SV=2 0.999999 58.9815 0.999999 58.9815 3.90089E-05 114.87 0 0 0.999893 39.6997 0.000740518 95.71 1 S YSQQQNSPQKHKN CDK1;CDK2;Proline-directed 0.0057 3.90089E-05 114.87 _TPVQYSQQQNpSPQK_ TPVQYSQQQNS(1)PQK T(-114.87)PVQY(-103.08)S(-58.98)QQQNS(58.98)PQK 11 2 856.88562 -0.6459 163180 49890 0 0 113290 0 0 0 718 567 1015 1015 4866 5532 46665 28581 Mix4_TiO2_Reinj_1_5 6696 46665 28581 Mix4_TiO2_Reinj_1_5 6696 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 1 78.7365 1 69.0074 1.47495E-17 150.33 0 0 1 78.7365 5.86298E-25 170.97 0.999994 52.0543 0.000238546 91.704 0.999672 34.844 4.02286E-07 110.2 0.999989 49.7563 0.000141509 94.613 1 S QMTRRFSADEQFF CAMK2;CHK1;CK1;CK2;PKA 0.004788 5.86298E-25 170.97 _RFpSADEQFFSVGQAASSSAHSSK_ RFS(1)ADEQFFSVGQAASSSAHSSK RFS(78.74)ADEQFFS(-78.74)VGQAAS(-170.97)S(-170.97)S(-170.97)AHS(-170.97)S(-170.97)K 3 3 837.70272 -0.19145 12616000 1696700 0 0 9609200 60441 764530 485400 719 567 729 729 5453 6205 53164 32503 Mix4_TiO2_Reinj_1_5 7282 53163 32502 Mix4_TiO2_1_5 6467 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 1 87.3593 1 96.9566 1.22793E-06 124.57 1 87.3593 1.79298E-06 118.65 1 S LSAHRKSLNLVDS AURORA;AURORA-1;PKA 0.020748 1.22793E-06 124.57 _pSLNLVDSPQPLLEK_ S(1)LNLVDSPQPLLEK S(87.36)LNLVDS(-87.36)PQPLLEK 1 2 816.91585 0.32025 746290 201010 0 0 545280 0 0 0 720 567;568 5;5 5 5522 6287 53909 32973 Mix4_InSol_Tio2_Reinj_2 3520 53906 32970 Mix4_InSol_TiO2_1 4785 P46019;P46020;P46020-2 P46019;P46020 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1;>sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P4 0.636018 2.53383 0.0324214 -14.6005 0.486007 14.601 0 0 0.0790821 -10.6608 0.0162774 61.893 0.636018 2.53383 0.0692099 45.509 1 S __MRSRSNSGVRL CAMK2;PKA/AKT 0.00111111 0.0162774 61.893 _pSNSGVRLDGYAR_ S(0.636)NS(0.355)GVRLDGY(0.009)AR S(2.53)NS(-2.53)GVRLDGY(-18.45)AR 1 2 687.81172 -0.51446 72461 0 0 0 0 0 0 72461 721 567;568 7;7 7 5522 6287 53906 32970 Mix4_InSol_TiO2_1 4785 53906 32970 Mix4_InSol_TiO2_1 4785 P46019;P46020;P46020-2 P46019;P46020 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1;>sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P4 0.999772 36.424 0.935157 14.6005 0.486007 14.601 0 0 0.999772 36.424 0.0162774 61.893 0.995905 23.9338 0.0692099 45.509 1 S MRSRSNSGVRLDG CAMK2;CK1;PKA/AKT 0.001764 0.0162774 61.893 _SNpSGVRLDGYAR_ SNS(1)GVRLDGYAR S(-36.42)NS(36.42)GVRLDGY(-61.89)AR 3 3 458.87691 -0.022827 2518500 14750 0 0 0 0 1539400 964370 722 567 975 975 5840 6659;6660 57583 35052 Mix4_TiO2_Reinj_1_5 4895 57583 35052 Mix4_TiO2_Reinj_1_5 4895 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 0.817387 6.78809 0.817387 6.78809 0.00409596 76.539 2 S SVRPIHSSTSSPT GSK3 0.081 0.00409596 76.539 _SVRPIHpSSTpSSPTISIHEVGHTGVTK_ SVRPIHS(0.817)S(0.188)T(0.102)S(0.454)S(0.385)PT(0.053)ISIHEVGHTGVTK S(-42.61)VRPIHS(6.79)S(-6.79)T(-6.79)S(0.74)S(-0.74)PT(-9.56)IS(-36.33)IHEVGHT(-68.98)GVT(-76.28)K 7 3 958.78974 -0.4194 685080 0 0 0 685080 0 0 0 723 567 976 976 5840 6659;6660 57581 35050 Mix4_TiO2_Reinj_1_5 4702 57581 35050 Mix4_TiO2_Reinj_1_5 4702 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 0.19678 0 0.19678 0 3.50864E-07 101.08 1 S VRPIHSSTSSPTI 3.50864E-07 101.08 _SVRPIHpSSTSSPTISIHEVGHTGVTK_ S(0.01)VRPIHS(0.197)S(0.197)T(0.197)S(0.197)S(0.197)PT(0.006)ISIHEVGHTGVTK S(-13.02)VRPIHS(0)S(0)T(0)S(0)S(0)PT(-14.95)IS(-66.18)IHEVGHT(-101.08)GVT(-101.08)K 8 3 932.1343 -0.0071434 0 0 0 0 0 0 0 0 724 567 978 978 5840 6659;6660 57583 35052 Mix4_TiO2_Reinj_1_5 4895 57583 35052 Mix4_TiO2_Reinj_1_5 4895 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 0.454316 0.735231 0.454316 0.735231 0.00409596 76.539 2 S PIHSSTSSPTISI CK1 0.081 0.00409596 76.539 _SVRPIHpSSTpSSPTISIHEVGHTGVTK_ SVRPIHS(0.817)S(0.188)T(0.102)S(0.454)S(0.385)PT(0.053)ISIHEVGHTGVTK S(-42.61)VRPIHS(6.79)S(-6.79)T(-6.79)S(0.74)S(-0.74)PT(-9.56)IS(-36.33)IHEVGHT(-68.98)GVT(-76.28)K 10 3 958.78974 -0.4194 0 0 0 0 0 0 0 0 725 567 979 979 5840 6659;6660 57582 35051 Mix4_TiO2_Reinj_1_5 4703 57581 35050 Mix4_TiO2_Reinj_1_5 4702 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 0.831748 7.94635 0.831748 7.94635 3.50864E-07 101.08 1 S IHSSTSSPTISIH CK1;GSK3;Polo box;Proline-directed 0.00405 3.50864E-07 101.08 _SVRPIHSSTSpSPTISIHEVGHTGVTK_ SVRPIHSS(0.001)T(0.006)S(0.133)S(0.832)PT(0.028)ISIHEVGHTGVTK S(-77.48)VRPIHS(-44.24)S(-30.44)T(-21.43)S(-7.95)S(7.95)PT(-14.76)IS(-35.94)IHEVGHT(-59.6)GVT(-66.07)K 11 4 699.35254 0.13096 583040 0 0 0 583040 0 0 0 726 568 729 729 3423 3867 32166 19877 Mix4_TiO2_Reinj_1_5 7044 32166 19877 Mix4_TiO2_Reinj_1_5 7044 P46020;P46020-2 P46020 P46020 >sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P46020-2|KPB1_HUMAN Isoform C of Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens 0.993844 22.0799 0.993844 22.0799 1.59337E-06 113.64 1 S FQASRPSFNLLDS AURORA;CK1;PKA 0.038874 1.59337E-06 113.64 _LFQASRPpSFNLLDSPHPR_ LFQAS(0.006)RPS(0.994)FNLLDSPHPR LFQAS(-22.08)RPS(22.08)FNLLDS(-69.83)PHPR 8 3 721.35627 -0.15679 164610 0 0 0 164610 0 0 0 727 568 972 972 5841 6661 57588 35057 Mix4_TiO2_1_5 5634 57591 35061 Mix4_TiO2_Reinj_1_5 6368 P46020;P46020-2 P46020 P46020 >sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P46020-2|KPB1_HUMAN Isoform C of Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens 0.664157 5.04377 0.664157 5.04377 0.00305729 77.247 0 0 0.0590859 -11.6162 3.64191E-07 106.56 0 0 0.031839 -13.808 0.0177996 64.242 0.0143296 -14.2028 1.16456 29.669 1 S EFGVERSVRPTDS PLK1 0.033462 3.64191E-07 106.56 _pSVRPTDSNVSPAISIHEIGAVGATK_ S(0.664)VRPT(0.208)DS(0.115)NVS(0.013)PAISIHEIGAVGATK S(5.04)VRPT(-5.04)DS(-7.63)NVS(-17)PAIS(-51.32)IHEIGAVGAT(-77.25)K 1 3 862.76896 0.18376 535550 535550 0 0 0 0 0 0 728 568 978 978 5841 6661 57590 35060 Mix4_TiO2_Reinj_1_5 6276 57591 35061 Mix4_TiO2_Reinj_1_5 6368 P46020;P46020-2 P46020 P46020 >sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P46020-2|KPB1_HUMAN Isoform C of Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens 0.495973 1.41818 0.11468 -7.62783 0.00305729 77.247 0 0 0.495973 1.41818 3.64191E-07 106.56 0 0 0.164237 -6.68287 0.0177996 64.242 0.182998 -3.14072 1.16456 29.669 1 S SVRPTDSNVSPAI 3.64191E-07 106.56 _SVRPTDpSNVSPAISIHEIGAVGATK_ S(0.017)VRPT(0.098)DS(0.496)NVS(0.358)PAIS(0.031)IHEIGAVGATK S(-14.66)VRPT(-7.05)DS(1.42)NVS(-1.42)PAIS(-11.98)IHEIGAVGAT(-85.76)K 7 3 862.76896 0.024976 0 0 0 0 0 0 0 0 729 568 981 981 5841 6661 57586 35053 Mix4_InSol_TiO2_1 6775 57591 35061 Mix4_TiO2_Reinj_1_5 6368 P46020;P46020-2 P46020 P46020 >sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P46020-2|KPB1_HUMAN Isoform C of Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens 0.765169 6.68287 0.0163751 -14.7565 0.00305729 77.247 0 0 0.3578 -1.41818 3.64191E-07 106.56 0 0 0.765169 6.68287 0.0177996 64.242 0.377154 0 1.16456 29.669 1 S PTDSNVSPAISIH CK1;GSK3;Proline-directed 0.05 3.64191E-07 106.56 _SVRPTDSNVpSPAISIHEIGAVGATK_ S(0.032)VRPT(0.036)DS(0.164)NVS(0.765)PAIS(0.003)IHEIGAVGATK S(-13.81)VRPT(-13.24)DS(-6.68)NVS(6.68)PAIS(-24.84)IHEIGAVGAT(-63.12)K 10 3 862.76896 0.24162 136820 0 0 0 0 0 136820 0 730 569 732 732 2485 2824 23417 14567 Mix4_TiO2_Reinj_1_5 4179 23417 14567 Mix4_TiO2_Reinj_1_5 4179 P46087;P46087-2 P46087 P46087 >sp|P46087|NOP2_HUMAN Putative ribosomal RNA methyltransferase NOP2 OS=Homo sapiens GN=NOP2 PE=1 SV=2;>sp|P46087-2|NOP2_HUMAN Isoform 2 of Putative ribosomal RNA methyltransferase NOP2 OS=Homo sapiens GN=NOP2 0.848274 7.47661 0 0 0.848274 7.47661 0.0775074 47.474 1 S QTPAVLSPSKTQA CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 0.0775074 47.474 _GTDTQTPAVLpSPSK_ GTDTQTPAVLS(0.848)PS(0.152)K GT(-47.47)DT(-47.47)QT(-43.93)PAVLS(7.48)PS(-7.48)K 11 2 741.3478 -0.99434 121520 0 0 0 121520 0 0 0 731 570 113 113 403 461 3821 2272 Mix4_TiO2_Reinj_1_5 3706 3821 2272 Mix4_TiO2_Reinj_1_5 3706 P46379-3;P46379;P46379-2 P46379-3 P46379-3 >sp|P46379-3|BAT3_HUMAN Isoform 3 of Large proline-rich protein BAT3 OS=Homo sapiens GN=BAT3;>sp|P46379|BAT3_HUMAN Large proline-rich protein BAT3 OS=Homo sapiens GN=BAT3 PE=1 SV=2;>sp|P46379-2|BAT3_HUMAN Isoform 2 of Large proline-rich protein BAT3 OS=Hom 0.99896 29.992 0.959716 16.2009 0.478274 52.093 0.99896 29.992 5.54437E-13 130.9 0 0 0 0 1 S ATHGGGSPPGTRG Proline-directed 0.05 5.54437E-13 130.9 _APPQTHLPSGASSGTGSASATHGGGpSPPGTR_ APPQTHLPSGASSGTGSASATHGGGS(0.999)PPGT(0.001)R APPQT(-122.71)HLPS(-90.79)GAS(-97.06)S(-97.06)GT(-91.32)GS(-85.95)AS(-59.26)AT(-44.15)HGGGS(29.99)PPGT(-29.99)R 26 3 955.76857 -0.5506 977630 112790 0 0 864840 0 0 0 732 571 31 31 4890 5561 46966 28738 Mix4_TiO2_Reinj_1_6 7127 46966 28738 Mix4_TiO2_Reinj_1_6 7127 P46695 P46695 P46695 >sp|P46695|IEX1_HUMAN Radiation-inducible immediate-early gene IEX-1 OS=Homo sapiens GN=IER3 PE=1 SV=3 0.786456 5.66186 0.5 0 1.71711 12.752 0.786456 5.66186 2.44124E-11 124.49 1 S PGPRRGSGPEIFT CAMK2;CK2;PKA 0.004788 2.44124E-11 124.49 _RGpSGPEIFTFDPLPEPAAAPAGR_ RGS(0.786)GPEIFT(0.214)FDPLPEPAAAPAGR RGS(5.66)GPEIFT(-5.66)FDPLPEPAAAPAGR 3 3 811.7248 -0.041832 150800 34585 0 0 116220 0 0 0 733 572;641 218;207 218 3819 4316;4317 36297 22412 Mix4_TiO2_Reinj_1_4 8045 36287 22408 Mix4_TiO2_Reinj_1_4 7642 P46734;P46734-3;P46734-2;P52564;P52564-2 P46734;P52564 P46734 >sp|P46734|MP2K3_HUMAN Dual specificity mitogen-activated protein kinase kinase 3 OS=Homo sapiens GN=MAP2K3 PE=1 SV=2;>sp|P46734-3|MP2K3_HUMAN Isoform 3c of Dual specificity mitogen-activated protein kinase kinase 3 OS=Homo sapiens GN=MAP2K3;>sp|P46734-2|M 1 94.7168 1 111.213 6.00786E-16 165.69 1 94.7168 4.1626E-21 194.36 1 79.538 3.35707E-06 113.43 0.999996 56.1666 0.0334907 59.007 1 S SGYLVDSVAKTID;SGYLVDSVAKTMD NEK6 0.076 4.1626E-21 194.36 _MCDFGISGYLVDpSVAK_ MCDFGISGYLVDS(1)VAK MCDFGIS(-100.56)GY(-94.72)LVDS(94.72)VAK 13 2 921.39611 1.2034 1147100 161900 0 0 813140 0 59518 112560 734 577 1792 1792 1839 2076 16829 10126 Mix4_TiO2_1_1 4817 16831 10128 Mix4_TiO2_Reinj_1_1 5631 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.981232 17.1897 0.981232 17.1897 0.0300532 59.353 0 0 0.122863 -8.32151 0.0206635 62.716 0 0 0 0 1 S PLTPRESSPLYSP CK1;PKA 0.042 0.0206635 62.716 _EpSSPLYSPTFSDSTSAVK_ ES(0.981)S(0.019)PLYSPTFSDSTSAVK ES(17.19)S(-17.19)PLY(-46.9)S(-59.35)PT(-59.35)FS(-59.35)DS(-59.35)T(-59.35)S(-59.35)AVK 2 2 991.93517 1.0619 38499 38499 0 0 0 0 0 0 735 577 1793 1793 1839 2076 16830 10127 Mix4_TiO2_Reinj_1_1 5480 16831 10128 Mix4_TiO2_Reinj_1_1 5631 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.834781 8.32151 0.0187414 -17.1897 0.0300532 59.353 0 0 0.834781 8.32151 0.0206635 62.716 0 0 0 0 1 S LTPRESSPLYSPT CAMK2;GSK3;Polo box;Proline-directed 0.00405 0.0206635 62.716 _ESpSPLYSPTFSDSTSAVK_ ES(0.123)S(0.835)PLY(0.006)S(0.006)PT(0.006)FS(0.006)DS(0.006)T(0.006)S(0.006)AVK ES(-8.32)S(8.32)PLY(-21.4)S(-21.4)PT(-21.4)FS(-21.4)DS(-21.4)T(-21.4)S(-21.4)AVK 3 2 991.93517 1.1327 196130 0 0 0 196130 0 0 0 736 577 1797 1797 1839 2076 16831 10128 Mix4_TiO2_Reinj_1_1 5631 16831 10128 Mix4_TiO2_Reinj_1_1 5631 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.720901 4.44671 1.13878E-06 -59.3533 0.0300532 59.353 0 0 0.720901 4.44671 0.0206635 62.716 0 0 0 0 1 S ESSPLYSPTFSDS CK1;GSK3;Proline-directed 0.05 0.0206635 62.716 _ESSPLYpSPTFSDSTSAVK_ ESSPLY(0.002)S(0.721)PT(0.259)FS(0.012)DS(0.001)T(0.004)S(0.001)AVK ES(-49.34)S(-42.16)PLY(-24.71)S(4.45)PT(-4.45)FS(-17.63)DS(-29.55)T(-23.03)S(-29.32)AVK 7 2 991.93517 0.31416 98671 0 0 0 98671 0 0 0 737 577 1427 1427 2092 2369 19152 11645 Mix4_TiO2_Reinj_1_1 3441 19152 11645 Mix4_TiO2_Reinj_1_1 3441 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 1 39.0254 0 0 1 39.0254 0.0962742 39.025 0 0 1 18.2766 0.440767 18.277 0 0 1 S SGRGAESPFEEKS CK2;Proline-directed 0.05 0.0962742 39.025 _GAEpSPFEEK_ GAES(1)PFEEK GAES(39.03)PFEEK 4 2 537.21299 0.84525 210780 0 0 0 121090 0 89694 0 738 577 1501 1501 3113 3536 29638 18449 Mix4_TiO2_Reinj_1_1 6886 29638 18449 Mix4_TiO2_Reinj_1_1 6886 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.963265 14.1867 0 0 0.963265 14.1867 0.000990062 81.989 1 S RKLGDVSPTQIDV Proline-directed 0.05 0.000990062 81.989 _KLGDVpSPTQIDVSQFGSFK_ KLGDVS(0.963)PT(0.037)QIDVSQFGSFK KLGDVS(14.19)PT(-14.19)QIDVS(-81.99)QFGS(-81.99)FK 6 3 711.68031 0.27135 189400 0 0 0 189400 0 0 0 739 577 2271 2271 5394 6139 52529 32117 Mix4_TiO2_Reinj_1_2 3032 52529 32117 Mix4_TiO2_Reinj_1_2 3032 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 1 91.583 0 0 1 91.583 0.000185401 102.19 1 S SKPLAASPKPAGL CDK1;NEK6;Proline-directed 0.0057 0.000185401 102.19 _SKPLAApSPKPAGLK_ SKPLAAS(1)PKPAGLK S(-91.58)KPLAAS(91.58)PKPAGLK 7 2 722.89981 0.98622 342900 0 0 0 342900 0 0 0 740 577 1265 1265 5582 6362 54609 33428 Mix4_TiO2_Reinj_1_1 4673 54609 33428 Mix4_TiO2_Reinj_1_1 4673 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.982044 17.3791 0.982044 17.3791 0.000191827 101.66 1 S LSPSPPSPLEKTP CK1;CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000191827 101.66 _SPSLSPSPPpSPLEK_ SPSLSPS(0.018)PPS(0.982)PLEK S(-101.66)PS(-101.66)LS(-77.52)PS(-17.38)PPS(17.38)PLEK 10 2 751.86055 0.31717 145390 0 0 0 145390 0 0 0 741 577 2098 2098 5967 6804 58906 35749 Mix4_TiO2_Reinj_1_3 9198 58907 35750 Mix4_TiO2_Reinj_1_5 8964 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.454443 0.247578 0.450232 0.382647 0.00749056 81.304 0 0 0.454443 0.247578 0.00424972 88.903 1 S HPKTELSPSFINP Proline-directed 0.05 0.00424972 88.903 _TELpSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGK_ T(0.429)ELS(0.454)PS(0.116)FINPNPLEWFAS(0.001)EEPTEESEKPLTQSGGAPPPPGGK T(-0.25)ELS(0.25)PS(-5.95)FINPNPLEWFAS(-28.93)EEPT(-37.25)EES(-39.67)EKPLT(-43.12)QS(-44.37)GGAPPPPGGK 4 3 1510.3739 -0.0016185 0 0 0 0 0 0 0 0 742 577 2100 2100 5967 6804 58907 35750 Mix4_TiO2_Reinj_1_5 8964 58907 35750 Mix4_TiO2_Reinj_1_5 8964 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.638482 5.48094 0.136325 -5.18861 0.00749056 81.304 0 0 0.638482 5.48094 0.00424972 88.903 1 S KTELSPSFINPNP NEK6 0.076 0.00424972 88.903 _TELSPpSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGK_ T(0.181)ELS(0.181)PS(0.638)FINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGK T(-5.48)ELS(-5.48)PS(5.48)FINPNPLEWFAS(-42.7)EEPT(-54.62)EES(-59.04)EKPLT(-62.68)QS(-63.2)GGAPPPPGGK 6 3 1510.3739 0.33392 617570 0 0 0 617570 0 0 0 743 577 1965 1965 6267 7159 62464 37998 Mix4_TiO2_1_1 3736 62464 37998 Mix4_TiO2_1_1 3736 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.858842 10.6493 0.858842 10.6493 0.0162292 67.409 0 0 0.807522 8.66159 0.0187567 65.015 0 0 0 0 1 S ISEKTTSPPEVSG CK2;Proline-directed 0.05 0.0162292 67.409 _TTpSPPEVSGYSYEK_ T(0.067)T(0.074)S(0.859)PPEVSGYSYEK T(-11.07)T(-10.65)S(10.65)PPEVS(-67.41)GY(-67.41)S(-67.41)Y(-67.41)EK 3 2 812.84255 -0.13962 167800 25085 0 0 142720 0 0 0 744 577 1396 1396 6494 7430;7431 65620 40243 Mix4_TiO2_Reinj_1_1 8313 65620 40243 Mix4_TiO2_Reinj_1_1 8313 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 1 80.155 0.863474 9.18528 1.5977 24.679 0 0 1 80.155 7.92447E-08 114.26 2 S PIEKVLSPLRSPP CDK1;CDK2;CHK1;ERK/MAPK;GSK3;PKD;Proline-directed 0.0034 7.92447E-08 114.26 _VLpSPLRpSPPLIGSESAYESFLSADDK_ VLS(1)PLRS(1)PPLIGSESAYESFLSADDK VLS(80.15)PLRS(65.83)PPLIGS(-65.83)ES(-72.98)AY(-71.85)ES(-80.15)FLS(-105.33)ADDK 3 3 980.12228 0.13984 350680 83179 0 0 267500 0 0 0 745 577 1400 1400 6494 7430;7431 65616 40241 Mix4_TiO2_1_1 7222 65616 40241 Mix4_TiO2_1_1 7222 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.806324 6.19436 0.806324 6.19436 1.03481E-07 113.09 0 0 1 65.8276 7.92447E-08 114.26 1 S VLSPLRSPPLIGS CK1;Proline-directed 0.05 1.03481E-07 113.09 _VLSPLRpSPPLIGSESAYESFLSADDK_ VLS(0.194)PLRS(0.806)PPLIGSESAYESFLSADDK VLS(-6.19)PLRS(6.19)PPLIGS(-62.59)ES(-68.58)AY(-67.18)ES(-84.89)FLS(-100.02)ADDK 7 3 953.46683 1.4308 84791 84791 0 0 0 0 0 0 746 577 1779 1779 6571 7520 66562 40823 Mix4_TiO2_1_1 3280 66562 40823 Mix4_TiO2_1_1 3280 P46821 P46821 P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B OS=Homo sapiens GN=MAP1B PE=1 SV=1 0.999933 41.7361 0.999933 41.7361 0.082535 41.736 0 0 0.962284 14.0678 0.498268 14.068 0 0 0 0 1 S LEGEKLSPKSDIS CDK1;Proline-directed 0.0057 0.082535 41.736 _VQSLEGEKLpSPK_ VQSLEGEKLS(1)PK VQS(-41.74)LEGEKLS(41.74)PK 10 2 697.84998 -0.26588 93735 16934 0 0 76801 0 0 0 747 582 70 70 4942 5618 47523 29006 Mix4_TiO2_Reinj_1_3 8542 47523 29006 Mix4_TiO2_Reinj_1_3 8542 P47897 P47897 P47897 >sp|P47897|SYQ_HUMAN Glutaminyl-tRNA synthetase OS=Homo sapiens GN=QARS PE=1 SV=1 0.98763 19.6375 0 0 0.98763 19.6375 0.0245656 58.172 1 S RDTRRLSFLVSYI AURORA;AURORA-A;CAMK2;CK1;GSK3;PKA 0.004788 0.0245656 58.172 _RLpSFLVSYIASK_ RLS(0.988)FLVS(0.011)Y(0.002)IASK RLS(19.64)FLVS(-19.64)Y(-27.82)IAS(-58.17)K 3 2 732.38653 0.17525 111360 0 0 0 111360 0 0 0 748 584 417 417 1626;6316 1826;7216 63185 38507 Mix4_TiO2_Reinj_1_4 5526 14951 9046 Mix4_TiO2_Reinj_1_5 5309 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 0.986065 18.5015 0 0 0.986065 18.5015 2.1698E-16 137.88 0.982925 19.92 0.000842138 84.515 0.960831 14.2084 0.143981 45.071 1 S HREKTYSECEDGT CK2 0.117 2.1698E-16 137.88 _TYpSECEDGTYSPEISWHHR_ T(0.014)YS(0.986)ECEDGTYSPEISWHHR T(-18.5)Y(-64.43)S(18.5)ECEDGT(-49.59)Y(-88.28)S(-88.42)PEIS(-119.1)WHHR 3 3 811.98624 -0.18469 4362700 0 0 0 4009800 0 204640 148250 749 584 425 425 1626;6316 1826;7216 63181 38503 Mix4_InSol_TiO2_1 5939 14951 9046 Mix4_TiO2_Reinj_1_5 5309 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 0.966033 17.4333 0 0 0.69381 4.65044 2.1698E-16 137.88 0.966033 17.4333 0.000842138 84.515 2.98894E-05 -45.0713 0.143981 45.071 1 S CEDGTYSPEISWH GSK3;Proline-directed 0.05 2.1698E-16 137.88 _TYSECEDGTYpSPEISWHHR_ TYSECEDGT(0.013)Y(0.017)S(0.966)PEIS(0.003)WHHR T(-84.51)Y(-84.51)S(-69.38)ECEDGT(-18.59)Y(-17.43)S(17.43)PEIS(-24.85)WHHR 11 3 811.98624 -0.0019432 370990 0 0 0 261550 0 109440 0 750 584 439 439 2429;2430;2494 2752;2753;2834 22764 14218 Mix4_InSol_TiO2_2 1322 22779 14249 Mix4_TiO2_Reinj_1_4 1536 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 0.994353 22.4569 0.22203 -3.78248 0.0122671 71.885 0 0 0.153312 -7.42147 3.61798E-21 162.34 0 0 0.994353 22.4569 0.00169599 78.982 0.90422 9.76594 0.000575096 89.076 1 S RKGTKGSEDSPPK 3.61798E-21 162.34 _GpSEDSPPKHAGNNESHSSR_ GS(0.994)EDS(0.006)PPKHAGNNESHSSR GS(22.46)EDS(-22.46)PPKHAGNNES(-74.12)HS(-74.12)S(-74.12)R 2 3 691.61877 -0.27668 2428100 117.28 0 0 0 0 0 146070 2282000 751 584 442 442 2429;2430;2494 2752;2753;2834 22753 14201 Mix4_TiO2_1_3 1146 22779 14249 Mix4_TiO2_Reinj_1_4 1536 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 1 71.8846 1 71.8846 0.0122671 71.885 0 0 0.999999 59.0711 3.61798E-21 162.34 0 0 0.970774 15.7003 0.00169599 78.982 0.991013 20.4525 0.000575096 89.076 1 S TKGSEDSPPKHAG CDK1;CDK2;CK1;Proline-directed 0.0057 3.61798E-21 162.34 _GSEDpSPPK_ GSEDS(1)PPK GS(-71.88)EDS(71.88)PPK 5 2 448.6735 -0.22106 24549000 1185.7 265780 0 0 16456000 0 5735700 2092000 752 584 11 11 6088 6944 60157 36443 Mix4_TiO2_Reinj_1_3 3669 60157 36443 Mix4_TiO2_Reinj_1_3 3669 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 0.99928 31.4265 0.904426 12.7706 0.504004 12.771 0 0 0.99928 31.4265 0.00382128 70.071 0 0 0 0 1 S VGSRTLSKDDVNY CAMK2;CK1;CK2 0.042 0.00382128 70.071 _TLpSKDDVNYK_ T(0.001)LS(0.999)KDDVNYK T(-31.43)LS(31.43)KDDVNY(-70.07)K 3 2 631.78685 0.51875 785020 36697 0 0 748330 0 0 0 753 585 339 339 65;67;4593 77;80;5214 667 425 Mix4_InSol_TiO2_1 2123 678 441 Mix4_TiO2_1_4 1389 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.873898 8.47168 0.333074 0 1.54851E-77 283.56 3.98708E-12 -113.532 2.85475E-32 181.48 0.333333 0 3.27832E-65 263.47 0.873898 8.47168 8.47293E-39 203.67 0.606482 2.43344 2.05083E-32 185.36 1 S AAQQAASSSGQGQ 1.54851E-77 283.56 _AAQQAApSSSGQGQQAQTPTGK_ AAQQAAS(0.874)S(0.124)S(0.002)GQGQQAQTPTGK AAQQAAS(8.47)S(-8.47)S(-26.74)GQGQQAQT(-81.89)PT(-81.89)GK 7 2 1041.466 -1.3373 125330 0.0014517 0 0 0 0 0 56090 69238 754 585 340 340 65;67;4593 77;80;5214 666 424 Mix4_InSol_TiO2_1 2086 678 441 Mix4_TiO2_1_4 1389 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.491485 0 0.343863 0 1.54851E-77 283.56 1.08915E-11 -109.168 2.85475E-32 181.48 0.333333 0 3.27832E-65 263.47 0.491485 0 8.47293E-39 203.67 0.488347 0 2.05083E-32 185.36 1 S AQQAASSSGQGQQ 1.54851E-77 283.56 _AAQQAASpSSGQGQQAQTPTGK_ AAQQAAS(0.017)S(0.491)S(0.491)GQGQQAQTPTGK AAQQAAS(-14.61)S(0)S(0)GQGQQAQT(-47.08)PT(-57.85)GK 8 3 694.64644 -0.22217 0 0 0 0 0 0 0 0 0 755 585 341 341 65;67;4593 77;80;5214 680 445 Mix4_TiO2_1_4 1527 678 441 Mix4_TiO2_1_4 1389 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.929008 13.5313 0.929008 13.5313 1.54851E-77 283.56 1.08915E-11 -109.168 2.85475E-32 181.48 0.333333 0 3.27832E-65 263.47 0.491485 0 8.47293E-39 203.67 0.488347 0 2.05083E-32 185.36 1 S QQAASSSGQGQQA 1.54851E-77 283.56 _AAQQAASSpSGQGQQAQTPTGK_ AAQQAAS(0.041)S(0.03)S(0.929)GQGQQAQTPTGK AAQQAAS(-13.53)S(-14.94)S(13.53)GQGQQAQT(-100.79)PT(-126.75)GK 9 2 1041.466 -3.2337 77130 0.00089345 77130 0 0 0 0 0 0 756 585 3 3 535 608 5013 3024 Mix4_InSol_TiO2_1 5794 5014 3025 Mix4_TiO2_1_2 3792 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.901643 9.7289 0.540974 1.44817 0.0202493 64.37 0.125993 -8.31682 0.0746064 51.294 0.901643 9.7289 0.103558 46.083 0 0 1 S ____MASSSGSKA GSK3 0.081 0.0202493 64.37 _(ac)ApSSSGSKAEFIVGGK_ AS(0.902)S(0.096)S(0.002)GSKAEFIVGGK AS(9.73)S(-9.73)S(-26.37)GS(-34.71)KAEFIVGGK 2 2 773.86108 0.14966 290490 89069 0 0 0 0 201420 0 757 585 5 5 535 608 5015 3027 Mix4_TiO2_Reinj_1_2 4657 5014 3025 Mix4_TiO2_1_2 3792 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.85512 8.31682 0.387578 -1.44817 0.0202493 64.37 0.85512 8.31682 0.0746064 51.294 0.00208085 -26.3679 0.103558 46.083 0 0 1 S __MASSSGSKAEF 0.0202493 64.37 _(ac)ASSpSGSKAEFIVGGK_ AS(0.126)S(0.016)S(0.855)GS(0.003)KAEFIVGGK AS(-8.32)S(-17.24)S(8.32)GS(-24.94)KAEFIVGGK 4 2 773.86108 0.43778 278900 0 0 0 278900 0 0 0 758 585 156 156 671;672 772;773 6454 3841 Mix4_TiO2_Reinj_1_4 2960 6454 3841 Mix4_TiO2_Reinj_1_4 2960 P48729-2 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 1 63.943 1 54.2101 0.0274004 54.21 1 8.22116 1.01503 8.2212 1 63.943 0.00689103 63.943 1 23.3376 0.316212 23.338 1 22.5598 0.212454 30.739 1 S CNKCLESPVGKRK Proline-directed 0.05 0.00689103 63.943 _CLEpSPVGKR_ CLES(1)PVGKR CLES(63.94)PVGKR 4 2 563.25975 0.52038 6142600 487350 18407 0 2506400 0 1589000 1541500 759 585 360 360 4749 5395 45313 27719 Mix4_InSol_Tio2_Reinj_1 1141 45313 27719 Mix4_InSol_Tio2_Reinj_1 1141 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.999816 37.4633 0 0 0.999816 37.4633 0.0273729 53.493 1 S QTDKTKSNMKGF_ 0.0273729 53.493 _QTDKTKpSNMK_ QTDKTKS(1)NMK QT(-53.49)DKT(-37.46)KS(37.46)NMK 7 2 630.78633 -1.1199 1143700 0 0 0 0 0 0 1143700 760 586 382 382 2110;2111 2391;2392;2393 19399 11816 Mix4_TiO2_Reinj_1_4 5525 19397 11812 Mix4_TiO2_1_4 4784 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.894613 9.57083 0.890328 9.10332 1.0796E-21 198.98 0 0 0.894613 9.57083 1.38775E-15 178.44 0.362816 -2.40268 2.89716E-11 158.84 0.748868 5.38068 1.64378E-06 120.2 1 S GAPVNISSSDLTG CK2 0.117 1.0796E-21 198.98 _GAPVNIpSSSDLTGR_ GAPVNIS(0.895)S(0.099)S(0.007)DLTGR GAPVNIS(9.57)S(-9.57)S(-21.3)DLT(-95.36)GR 7 2 727.33777 0.016483 7296000 1886900 0 0 5312400 0 0 96695 761 586 383 383 2110;2111 2391;2392;2393 19396 11811 Mix4_TiO2_1_4 4677 19397 11812 Mix4_TiO2_1_4 4784 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.753234 7.85879 0.753234 7.85879 1.0796E-21 198.98 0 0 0.497562 0 1.38775E-15 178.44 0.630892 2.40268 2.89716E-11 158.84 0.581095 1.94201 1.64378E-06 120.2 1 S APVNISSSDLTGR 1.0796E-21 198.98 _GAPVNISpSSDLTGR_ GAPVNIS(0.123)S(0.753)S(0.123)DLTGR GAPVNIS(-7.86)S(7.86)S(-7.86)DLT(-38.13)GR 8 2 727.33777 0.021684 1429300 63371 0 0 0 0 775140 590770 762 586 384 384 2110;2111 2391;2392;2393 19393 11808 Mix4_InSol_Tio2_Reinj_1 6035 19397 11812 Mix4_TiO2_1_4 4784 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.914095 10.3053 0.371022 -2.68352 2.29566E-05 116.26 0 0 0.903522 9.6902 1.2005E-06 124.86 0.79432 5.89085 2.89716E-11 158.84 0.914095 10.3053 1.64378E-06 120.2 1 S PVNISSSDLTGRQ 1.0796E-21 198.98 _GAPVNISSpSDLTGR_ GAPVNISS(0.085)S(0.914)DLT(0.001)GR GAPVNIS(-37.4)S(-10.31)S(10.31)DLT(-32.33)GR 9 2 727.33777 0.16691 303430 0 0 0 0 0 177240 126190 763 586 328 328 2315;2316 2618;2619;2620;2621 21464 13151 Mix4_InSol_TiO2_1 4473 21446 13146 Mix4_TiO2_Reinj_1_4 3045 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.986379 17.0047 0.879623 8.52468 0.0978909 38.91 0 0 0.820523 6.57579 0.00455417 69.784 0.986379 17.0047 0.0394151 51.775 0.900495 8.58065 0.0634126 44.658 2 S ATRGLPSTASGRL 0.00455417 69.784 _GLPpSTApSGRLR_ GLPS(0.986)T(0.317)AS(0.697)GRLR GLPS(17)T(-3.53)AS(3.53)GRLR 4 2 637.78633 0.043316 1833500 427200 0 0 815680 0 308470 282110 764 586 331 331 2315;2316 2618;2619;2620;2621 21425 13134 Mix4_InSol_Tio2_Reinj_1 3074 21431 13142 Mix4_TiO2_Reinj_1_4 3079 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.999119 31.254 0.994196 22.4145 0.0404845 50.067 0 0 0.991272 20.9146 0.0152214 58.067 0.995822 26.782 0.0422994 49.492 0.999119 31.254 0.0422995 49.492 1 S GLPSTASGRLRGT CK1 0.081 0.0152214 58.067 _GLPSTApSGR_ GLPST(0.001)AS(0.999)GR GLPS(-38.79)T(-31.25)AS(31.25)GR 7 2 463.21058 -0.052285 10711000 1286400 0 0 5114100 0 2779100 1531600 765 586 350 350 2504;2505;3694;3695 2844;2845;2846;2847;2848;4165;4166;4167 23580 14670 Mix4_InSol_Tio2_Reinj_1 5674 34800 21596 Mix4_TiO2_Reinj_1_4 4587 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.384443 0 0.151865 -2.44538 0.0245207 68.767 0.126481 -6.93376 0.907724 42.156 0.308015 0 3.51356E-11 118.78 0.236638 0 0.0365223 63.425 0.384443 0 0.0387768 68.836 1 S TPLTPTSHTANTS 4.82887E-45 200.14 _GTQEVAPPTPLTPpTSHTANTSPRPVSGMER_ GTQEVAPPT(0.014)PLT(0.109)PT(0.384)S(0.384)HT(0.085)ANT(0.012)S(0.012)PRPVSGMER GT(-51.96)QEVAPPT(-14.35)PLT(-5.49)PT(0)S(0)HT(-6.57)ANT(-15.18)S(-15.18)PRPVS(-30.06)GMER 15 3 1066.1746 0.28781 0 0 0 0 0 0 0 0 766 586 356 356 2504;2505;3694;3695 2844;2845;2846;2847;2848;4165;4166;4167 23577 14667 Mix4_InSol_TiO2_1 5733 34800 21596 Mix4_TiO2_Reinj_1_4 4587 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.709428 6.82753 0.424571 0.359742 1.90689 17.926 0.030358 -13.1313 0.907724 42.156 0.690138 6.82514 4.82887E-45 200.14 0.709428 6.82753 0.0365223 63.425 0.583929 4.79972 0.0387768 68.836 1 S SHTANTSPRPVSG CDK1;CK1;Proline-directed 0.0057 4.82887E-45 200.14 _GTQEVAPPTPLTPTSHTANTpSPRPVSGMER_ GTQEVAPPTPLTPT(0.002)S(0.002)HT(0.008)ANT(0.131)S(0.709)PRPVS(0.147)GMER GT(-63.43)QEVAPPT(-46.84)PLT(-36.88)PT(-25.6)S(-25.6)HT(-19.4)ANT(-7.33)S(6.83)PRPVS(-6.83)GMER 21 3 1066.1746 -0.14864 1802400 0 0 0 595470 0 692780 514150 767 588 831 831 350 398 3270 1974 Mix4_TiO2_Reinj_1_6 3737 3270 1974 Mix4_TiO2_Reinj_1_6 3737 P48960;P48960-3;P48960-2 P48960 P48960 >sp|P48960|CD97_HUMAN CD97 antigen OS=Homo sapiens GN=CD97 PE=1 SV=4;>sp|P48960-3|CD97_HUMAN Isoform EGF(1,2,3,5) of CD97 antigen OS=Homo sapiens GN=CD97;>sp|P48960-2|CD97_HUMAN Isoform EGF(1,2,5) of CD97 antigen OS=Homo sapiens GN=CD97 0.99999 49.846 0.998821 29.2805 0.0679203 41.379 0.99999 49.846 0.00716978 63.246 0 0 0 0 1 S TRALRASESGI__ NEK6;PKA 0.042 0.00716978 63.246 _ALRApSESGI_ ALRAS(1)ESGI ALRAS(49.85)ES(-49.85)GI 5 2 492.23151 0.14156 133830 16826 0 0 117010 0 0 0 768 589 84 84 1998 2260 18149 10827 Mix4_InSol_Tio2_Reinj_1 4201 18151 10829 Mix4_TiO2_1_3 3303 P49023-3;P49023;P49023-2 P49023-3 P49023-3 >sp|P49023-3|PAXI_HUMAN Isoform Gamma of Paxillin OS=Homo sapiens GN=PXN;>sp|P49023|PAXI_HUMAN Paxillin OS=Homo sapiens GN=PXN PE=1 SV=2;>sp|P49023-2|PAXI_HUMAN Isoform Alpha of Paxillin OS=Homo sapiens GN=PXN 0.535804 1.87971 0.0202969 -16.8337 7.97586E-10 120.18 0.0223051 -16.4082 4.93578E-07 116.73 0.0413823 -13.6468 0.00140193 81.814 0.535804 1.87971 0.0100674 72.063 1 S HQQPQSSSPVYGS 7.97586E-10 120.18 _FIHQQPQSpSSPVYGSSAK_ FIHQQPQS(0.112)S(0.536)S(0.348)PVY(0.004)GSSAK FIHQQPQS(-6.79)S(1.88)S(-1.88)PVY(-20.97)GS(-39.63)S(-52.72)AK 9 2 1014.4648 0.49233 57274 0 0 0 0 0 0 57274 769 589 85 85 1998 2260 18150 10828 Mix4_TiO2_1_3 3286 18151 10829 Mix4_TiO2_1_3 3303 P49023-3;P49023;P49023-2 P49023-3 P49023-3 >sp|P49023-3|PAXI_HUMAN Isoform Gamma of Paxillin OS=Homo sapiens GN=PXN;>sp|P49023|PAXI_HUMAN Paxillin OS=Homo sapiens GN=PXN PE=1 SV=2;>sp|P49023-2|PAXI_HUMAN Isoform Alpha of Paxillin OS=Homo sapiens GN=PXN 0.999624 34.3912 0.999624 34.3912 7.97586E-10 120.18 0.994376 22.5902 4.93578E-07 116.73 0.958279 13.6468 0.00140193 81.814 0.970313 15.3058 0.0100674 72.063 1 S QQPQSSSPVYGSS Polo box;Proline-directed 0.00405 7.97586E-10 120.18 _FIHQQPQSSpSPVYGSSAK_ FIHQQPQSSS(1)PVYGSSAK FIHQQPQS(-57.3)S(-34.39)S(34.39)PVY(-50.02)GS(-65.3)S(-65.3)AK 10 3 676.6456 -0.085232 1588000 206710 0 0 971880 0 259200 150180 770 589 106 106 6248 7138 61997 37554 Mix4_InSol_TiO2_1 3578 61997 37554 Mix4_InSol_TiO2_1 3578 P49023-3;P49023;P49023-2 P49023-3 P49023-3 >sp|P49023-3|PAXI_HUMAN Isoform Gamma of Paxillin OS=Homo sapiens GN=PXN;>sp|P49023|PAXI_HUMAN Paxillin OS=Homo sapiens GN=PXN PE=1 SV=2;>sp|P49023-2|PAXI_HUMAN Isoform Alpha of Paxillin OS=Homo sapiens GN=PXN 0.998876 29.4875 0 0 0 0 0.998876 29.4875 3.19465E-16 163.83 0.972373 15.468 0.000877481 90.493 1 S PQDSVGSPCSRVG CK1;ERK/MAPK;Proline-directed 0.0034 3.19465E-16 163.83 _TSSVSNPQDSVGpSPCSR_ TSSVSNPQDSVGS(0.999)PCS(0.001)R T(-159.86)S(-159.11)S(-159.11)VS(-154.22)NPQDS(-88.78)VGS(29.49)PCS(-29.49)R 13 2 922.87766 0.40565 179170 0 0 0 0 0 83210 95965 771 590 12 12 4962;5028 5643;5719 47893 29286 Mix4_InSol_Tio2_Reinj_1 3268 47893 29286 Mix4_InSol_Tio2_Reinj_1 3268 P49207 P49207 P49207 >sp|P49207|RL34_HUMAN 60S ribosomal protein L34 OS=Homo sapiens GN=RPL34 PE=1 SV=3 0.999034 30.1489 0 0 0 0 0 0 0.998741 29.1506 0.00491623 66.695 0.999034 30.1489 0.00389839 123.37 1 S TYRRRLSYNTASN CAMK2;PKA 0.004788 0.00389839 123.37 _RLpSYNTASNK_ RLS(0.999)YNT(0.001)ASNK RLS(30.15)Y(-67.48)NT(-30.15)AS(-113.11)NK 3 2 617.28481 0.093174 2223300 0 0 0 0 0 1143000 1080400 772 592 974 974 3412 3854 32069 19820 Mix4_TiO2_Reinj_1_1 7967 32069 19820 Mix4_TiO2_Reinj_1_1 7967 P49327 P49327 P49327 >sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens GN=FASN PE=1 SV=3 0.86593 8.10193 0 0 0.86593 8.10193 1.22574E-11 125 1 S LFDHPESPTPNPT ERK/MAPK;Proline-directed;WW GroupIV 0.000145 1.22574E-11 125 _LFDHPEpSPTPNPTEPLFLAQAEVYK_ LFDHPES(0.866)PT(0.134)PNPTEPLFLAQAEVYK LFDHPES(8.1)PT(-8.1)PNPT(-48.38)EPLFLAQAEVY(-125)K 7 3 974.13167 0.49572 189160 0 0 0 189160 0 0 0 773 594 362 362 23;2605 31;2965 251 146 Mix4_TiO2_1_4 4082 252 147 Mix4_TiO2_Reinj_1_4 4641 P49585 P49585 P49585 >sp|P49585|PCY1A_HUMAN Choline-phosphate cytidylyltransferase A OS=Homo sapiens GN=PCYT1A PE=1 SV=2 1 86.3646 1 86.3646 0.000105123 121.78 1 73.5087 1.37127E-05 137.89 1 68.1067 0.00267785 83.988 0.999941 42.2804 0.0993709 42.28 1 S AAAYDISEDEED_ CK2 0.117 1.37127E-05 137.89 _AAAYDIpSEDEED_ AAAYDIS(1)EDEED AAAY(-86.36)DIS(86.36)EDEED 7 2 704.24541 0.32237 328250 47155 0 0 186940 0 52333 41831 774 596 389 389 2103;2104 2381;2383 19268 11698 Mix4_InSol_Tio2_Reinj_1 4633 19252 11688 Mix4_TiO2_1_4 3537 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.394248 0 0.374216 -2.23033 2.9786E-11 158.36 0.369329 -1.89408 6.81167E-09 145.68 0.366267 -1.85049 1.6136E-06 120.52 0.394248 0 0.000141709 105.97 1 S GAPANVSSSDLTG CK2 0.117 2.9786E-11 158.36 _GAPANVpSSSDLTGRQEVSR_ GAPANVS(0.394)S(0.394)S(0.078)DLT(0.096)GRQEVS(0.038)R GAPANVS(0)S(0)S(-7.06)DLT(-6.14)GRQEVS(-10.15)R 7 2 1005.9657 -0.024885 0 0 0 0 0 0 0 0 0 775 596 390 390 2103;2104 2381;2383 19255 11694 Mix4_TiO2_Reinj_1_4 4361 19252 11688 Mix4_TiO2_1_4 3537 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.947883 13.5236 0.625396 2.23033 2.9786E-11 158.36 0.947883 13.5236 6.81167E-09 145.68 0.560851 1.85049 1.6136E-06 120.52 0.579637 1.91962 0.000141709 105.97 1 S APANVSSSDLTGR 2.9786E-11 158.36 _GAPANVSpSSDLTGR_ GAPANVS(0.042)S(0.948)S(0.01)DLTGR GAPANVS(-13.52)S(13.52)S(-19.77)DLT(-53.35)GR 8 2 706.3143 0.027512 2454000 32.865 681110 0 0 1544400 0 112280 116200 776 596 391 391 2103;2104 2381;2383 19253 11690 Mix4_TiO2_1_4 3762 19252 11688 Mix4_TiO2_1_4 3537 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.49357 0 0.49357 0 2.9786E-11 158.36 0.059427 -9.82837 6.81167E-09 145.68 0.14798 -3.35378 1.6136E-06 120.52 0.077622 -7.05784 0.000141709 105.97 1 S PANVSSSDLTGRQ 2.9786E-11 158.36 _GAPANVSpSSDLTGR_ GAPANVS(0.007)S(0.494)S(0.494)DLT(0.006)GR GAPANVS(-18.63)S(0)S(0)DLT(-19.08)GR 9 2 706.3143 0.23815 0 0 0 0 0 0 0 0 0 777 596 405 405 2856 3252;3253 27217 17020 Mix4_TiO2_Reinj_1_4 5913 27214 17016 Mix4_TiO2_1_4 5279 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.990381 20.3462 0.819862 6.72194 0.00226047 84.114 0.016754 -17.5 0.752415 17.5 0.990381 20.3462 0.0438659 56.852 1 S VSRIPASQTSVPF 0.00226047 84.114 _IPApSQTSVPFDHLGK_ IPAS(0.99)QT(0.009)SVPFDHLGK IPAS(20.35)QT(-20.35)S(-33.2)VPFDHLGK 4 2 838.90582 -0.27468 1499800 185990 0 0 1313800 0 0 0 778 596 408 408 2856 3252;3253 27214 17016 Mix4_TiO2_1_4 5279 27214 17016 Mix4_TiO2_1_4 5279 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.999892 40.9835 0.999892 40.9835 0.00226047 84.114 0.0410959 -13.6032 0.752415 17.5 0.983197 16.3361 0.00198281 85.997 1 S IPASQTSVPFDHL CK1 0.081 0.00226047 84.114 _IPASQTpSVPFDHLGK_ IPASQTS(1)VPFDHLGK IPAS(-45.44)QT(-40.98)S(40.98)VPFDHLGK 7 2 838.90582 0.36741 151200 151200 0 0 0 0 0 0 779 596 363 363 2883 3285 27608 17224 Mix4_TiO2_1_4 1657 27608 17224 Mix4_TiO2_1_4 1657 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.999205 30.9946 0.999205 30.9946 0.00193218 75.897 0.811927 6.3519 0.125114 35.991 0.999033 30.1418 0.00488813 66.781 0.5 0 0.749635 2.028 0.903059 9.69209 0.00193217 75.897 0.863267 8.00272 0.0115058 58.747 1 S QPAGNTSPRAISR CDK1;Proline-directed 0.0057 0.00193218 75.897 _IQPAGNTpSPR_ IQPAGNT(0.001)S(0.999)PR IQPAGNT(-30.99)S(30.99)PR 8 2 560.76097 -1.4555 23539000 3746300 667090 0 15083000 14084 3550700 478080 780 596 343 343 3700;5083 4172;5780 34846 21617 Mix4_TiO2_1_4 2767 49171 30023 Mix4_InSol_Tio2_Reinj_1 2998 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 1 71.2778 1 71.2778 0.012341 71.278 0 0 0 0 0.000656476 -31.8092 0.238599 31.809 4.94311E-08 -73.0567 0.0101702 73.057 1 S TANRLRSAAEPVA CAMK2;CK2 0.042 0.0101702 73.057 _LRpSAAEPVASTPASR_ LRS(1)AAEPVASTPASR LRS(71.28)AAEPVAS(-71.28)T(-71.28)PAS(-71.28)R 3 2 796.89324 -0.087341 65274 3.0556 65274 0 0 0 0 0 0 781 596 354 354 3700;5083 4172;5780 49171 30023 Mix4_InSol_Tio2_Reinj_1 2998 49171 30023 Mix4_InSol_Tio2_Reinj_1 2998 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.999232 33.0269 7.45111E-08 -71.2778 0.012341 71.278 0 0 0 0 0.995718 25.2552 0.238599 31.809 0.999232 33.0269 0.0101702 73.057 1 S VASTPASRIQPAG CK1 0.143 0.0101702 73.057 _SAAEPVASTPApSR_ SAAEPVASTPAS(0.999)R S(-73.06)AAEPVAS(-33.03)T(-35.68)PAS(33.03)R 12 2 662.30066 -2.3426 93545 4.3791 0 0 0 0 0 36577 56968 782 597 139 139 2313 2616 21409 13124 Mix4_TiO2_1_5 4536 21409 13124 Mix4_TiO2_1_5 4536 P49736 P49736 P49736 >sp|P49736|MCM2_HUMAN DNA replication licensing factor MCM2 OS=Homo sapiens GN=MCM2 PE=1 SV=4 1 106.096 1 106.096 4.44101E-16 168.35 0 0 0.999418 32.3473 0.000184886 97.486 0.999977 46.403 6.52001E-06 109 0.999918 40.8396 0.009065 73.986 1 S RGLLYDSDEEDEE CK2;NEK6 0.076 4.44101E-16 168.35 _GLLYDpSDEEDEERPAR_ GLLYDS(1)DEEDEERPAR GLLY(-106.1)DS(106.1)DEEDEERPAR 6 2 987.40985 0.30608 1491100 256070 0 0 1020400 0 120010 94679 783 597 27 27 2332 2641 21592 13223 Mix4_TiO2_1_5 2893 21592 13223 Mix4_TiO2_1_5 2893 P49736 P49736 P49736 >sp|P49736|MCM2_HUMAN DNA replication licensing factor MCM2 OS=Homo sapiens GN=MCM2 PE=1 SV=4 0.968695 14.9206 0.968695 14.9206 0.00526061 74.079 0.967505 14.8823 0.00788278 67.628 0.962361 14.2196 0.203764 30.008 0 0 1 S NDPLTSSPGRSSR CDK1;CDK2;GSK3;NEK6;Polo box;Proline-directed 0.00405 0.00526061 74.079 _GNDPLTSpSPGR_ GNDPLTS(0.031)S(0.969)PGR GNDPLT(-39.56)S(-14.92)S(14.92)PGR 8 2 590.75334 0.47815 240280 42346 0 0 160440 0 37490 0 784 598 634 634 2347 2656 21687 13274 Mix4_TiO2_Reinj_1_1 6190 21687 13274 Mix4_TiO2_Reinj_1_1 6190 P49750;P49750-3;P49750-2 P49750 P49750 >sp|P49750|YLPM1_HUMAN YLP motif-containing protein 1 OS=Homo sapiens GN=YLPM1 PE=1 SV=3;>sp|P49750-3|YLPM1_HUMAN Isoform 3 of YLP motif-containing protein 1 OS=Homo sapiens GN=YLPM1;>sp|P49750-2|YLPM1_HUMAN Isoform 2 of YLP motif-containing protein 1 OS=H 0.815235 10.6761 0 0 0.815235 10.6761 0.13354 44.402 0 0 1 S TPSTSLSPRQSGP CDK1;CK1;GSK3;Proline-directed 0.0057 0.13354 44.402 _GPASQFYITPSTSLpSPR_ GPASQFYIT(0.001)PS(0.057)T(0.057)S(0.07)LS(0.815)PR GPAS(-44.4)QFY(-44.4)IT(-29.78)PS(-11.55)T(-11.55)S(-10.68)LS(10.68)PR 15 2 944.94567 1.3368 77818 0 0 0 77818 0 0 0 785 599 677 677 3432 3876 32222 19903 Mix4_TiO2_Reinj_1_5 2809 32222 19903 Mix4_TiO2_Reinj_1_5 2809 P49756 P49756 P49756 >sp|P49756|RBM25_HUMAN RNA-binding protein 25 OS=Homo sapiens GN=RBM25 PE=1 SV=3 0.999944 42.4954 0.995829 23.7795 0.000210311 100.03 0.999944 42.4954 0.000150281 105.23 1 S KLGASNSPGQPNS Proline-directed 0.05 0.000150281 105.23 _LGASNpSPGQPNSVK_ LGASNS(1)PGQPNSVK LGAS(-42.5)NS(42.5)PGQPNS(-82.11)VK 6 2 718.33249 0.099282 253660 68822 0 0 184840 0 0 0 786 600 140 140 5818;6201 6634;7083 57351 34939 Mix4_TiO2_Reinj_1_4 6386 57349 34937 Mix4_TiO2_1_4 5708 P49759 P49759 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2 1 131.722 1 152.394 2.60023E-24 172.62 0 0 1 131.722 3.31451E-24 171.71 0 0 0.784651 5.88944 1.46127 21.171 1 S RRKRTRSVEDDEE CAMK2;CK2;PKA;PKA/AKT 0.001764 2.60023E-24 172.62 _pSVEDDEEGHLICQSGDVLSAR_ S(1)VEDDEEGHLICQSGDVLSAR S(131.72)VEDDEEGHLICQS(-131.72)GDVLS(-154.47)AR 1 2 1198.5072 -0.51615 3239200 996860 0 0 2200000 0 0 42321 787 600;1624 328;326 328 6649 7612;7613 67432 41421 Mix4_TiO2_Reinj_2_2 2327 67443 41435 Mix4_TiO2_1_4 5002 P49759;Q9HAZ1 P49759;Q9HAZ1 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2;>sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.15576 0 0.0181275 -15.2534 2.25458E-32 184.37 0.000744322 -28.2584 0.0298721 58.973 0.000443761 -27.4496 2.19665E-16 137.65 0.15576 0 0.69416 31.087 0.0398122 -8.38045 8.61479E-07 101.09 0.0546946 -9.81232 0.0838124 53.592 1 S KVVDFGSATYDDE 2.25458E-32 184.37 _VVDFGpSATYDDEHHSTLVSTR_ VVDFGS(0.156)AT(0.156)Y(0.156)DDEHHS(0.156)T(0.156)LVS(0.156)T(0.065)R VVDFGS(0)AT(0)Y(0)DDEHHS(0)T(0)LVS(0)T(-3.77)R 6 3 806.01994 -0.027522 0 0 0 0 0 0 0 0 788 600;1624 341;339 341 6649 7612;7613 67448 41443 Mix4_TiO2_Reinj_1_4 5558 67443 41435 Mix4_TiO2_1_4 5002 P49759;Q9HAZ1 P49759;Q9HAZ1 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2;>sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.783173 8.45705 0.40062 -1.00405 2.25458E-32 184.37 0.589603 6.04182 0.0298721 58.973 0.783173 8.45705 2.19665E-16 137.65 0.309829 0 0.69416 31.087 0.301705 -0.807639 8.61479E-07 101.09 0.523814 5.86119 0.0838124 53.592 1 S HHSTLVSTRHYRA CK1 0.143 2.25458E-32 184.37 _VVDFGSATYDDEHHSTLVpSTR_ VVDFGSATYDDEHHS(0.009)T(0.096)LVS(0.783)T(0.112)R VVDFGS(-69.99)AT(-64.29)Y(-56.65)DDEHHS(-19.36)T(-9.11)LVS(8.46)T(-8.46)R 19 3 806.01994 -0.062756 13778000 0 322700 0 13343000 0 0 112240 789 601 142 142 309;5817 352;6633 57340 34932 Mix4_TiO2_Reinj_1_5 7873 57340 34932 Mix4_TiO2_Reinj_1_5 7873 P49760;P49760-3 P49760 P49760 >sp|P49760|CLK2_HUMAN Dual specificity protein kinase CLK2 OS=Homo sapiens GN=CLK2 PE=1 SV=1;>sp|P49760-3|CLK2_HUMAN Isoform 3 of Dual specificity protein kinase CLK2 OS=Homo sapiens GN=CLK2 1 112.197 0 0 0.999922 41.0583 0.258639 41.058 1 112.197 3.41449E-11 129.02 0 0 1 S SSRRAKSVEDDAE CAMK2;CK2 0.002856 3.41449E-11 129.02 _pSVEDDAEGHLIYHVGDWLQER_ S(1)VEDDAEGHLIYHVGDWLQER S(112.2)VEDDAEGHLIY(-112.2)HVGDWLQER 1 3 850.04286 -0.13685 13530000 0 19869 0 13510000 0 0 0 790 601 50 50 4853;5020 5516;5709 46535 28511 Mix4_TiO2_Reinj_1_4 2420 46531 28507 Mix4_InSol_TiO2_1 2827 P49760;P49760-3;P49760-2 P49760 P49760 >sp|P49760|CLK2_HUMAN Dual specificity protein kinase CLK2 OS=Homo sapiens GN=CLK2 PE=1 SV=1;>sp|P49760-3|CLK2_HUMAN Isoform 3 of Dual specificity protein kinase CLK2 OS=Homo sapiens GN=CLK2;>sp|P49760-2|CLK2_HUMAN Isoform Short of Dual specificity protein 0.999807 37.1424 0 0 0.999807 37.1424 0.0716223 52.578 0.99955 33.4622 0.0193568 63.252 0.996437 24.4659 0.302384 32.058 1 S RRRREDSYHVRSR CAMK2;PKA/AKT;PLK1 0.001764 0.0193568 63.252 _REDpSYHVR_ REDS(1)YHVR REDS(37.14)Y(-37.14)HVR 4 2 571.24294 0.53333 4122400 0 0 0 3438300 0 357070 327090 791 602 224 224 657 755;756 6355 3770 Mix4_TiO2_1_4 4570 6355 3770 Mix4_TiO2_1_4 4570 P49761;P49761-1;P49761-3;P49761-2 P49761 P49761 >sp|P49761|CLK3_HUMAN Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3 PE=1 SV=3;>sp|P49761-1|CLK3_HUMAN Isoform Long of Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3;>sp|P49761-3|CLK3_HUMAN Isoform 3 of Dual specificity protein 0.978835 16.6524 0.978835 16.6524 0.0514109 56.348 1 95.3954 7.85277E-06 103.21 1 S YRCEERSPSFGED Proline-directed 0.05 0.0514109 56.348 _CEERpSPSFGEDYYGPSR_ CEERS(0.979)PS(0.021)FGEDYYGPSR CEERS(16.65)PS(-16.65)FGEDY(-56.35)Y(-56.35)GPS(-56.35)R 5 3 705.94198 0.31671 52724 52724 0 0 0 0 0 0 792 602 226 226 657 755;756 6356 3771 Mix4_TiO2_Reinj_1_4 5143 6355 3770 Mix4_TiO2_1_4 4570 P49761;P49761-1;P49761-3;P49761-2 P49761 P49761 >sp|P49761|CLK3_HUMAN Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3 PE=1 SV=3;>sp|P49761-1|CLK3_HUMAN Isoform Long of Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3;>sp|P49761-3|CLK3_HUMAN Isoform 3 of Dual specificity protein 0.803673 6.89624 0.999997 55.9066 0.013889 69.373 0.803673 6.89624 0.854235 18.758 1 S CEERSPSFGEDYY CAMK2;CK2 0.042 0.0514109 56.348 _CEERSPpSFGEDYYGPSR_ CEERS(0.164)PS(0.804)FGEDY(0.011)Y(0.011)GPS(0.011)R CEERS(-6.9)PS(6.9)FGEDY(-18.76)Y(-18.76)GPS(-18.76)R 7 3 705.94198 -0.076027 172710 0 0 0 172710 0 0 0 793 602 215 215 4833 5486 46136 28219 Mix4_TiO2_Reinj_1_5 1790 46134 28214 Mix4_TiO2_Reinj_1_3 1683 P49761;P49761-1;P49761-3;P49761-2 P49761 P49761 >sp|P49761|CLK3_HUMAN Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3 PE=1 SV=3;>sp|P49761-1|CLK3_HUMAN Isoform Long of Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3;>sp|P49761-3|CLK3_HUMAN Isoform 3 of Dual specificity protein 0.930174 11.2455 0.000113742 -39.4402 0.0405206 91.105 0 0 0.930174 11.2455 0.0136577 105.63 0 0 0 0 1 S YRERRDSDTYRCE CAMK2;PKA;PKA/AKT 0.00111111 0.0136577 105.63 _RDpSDTYR_ RDS(0.93)DT(0.07)YR RDS(11.25)DT(-11.25)Y(-60.2)R 3 2 496.6953 0.26491 253290 7.1937 0 0 0 253290 0 0 0 794 602 157 157 5079;5552;6786 5776;6327;7765 54345 33268 Mix4_TiO2_Reinj_1_4 5734 68818 42201 Mix4_InSol_TiO2_2 4541 P49761;P49761-1;P49761-3;P49761-2 P49761 P49761 >sp|P49761|CLK3_HUMAN Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3 PE=1 SV=3;>sp|P49761-1|CLK3_HUMAN Isoform Long of Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3;>sp|P49761-3|CLK3_HUMAN Isoform 3 of Dual specificity protein 1 75.1298 0.999253 31.3823 0.000224674 112.15 0.950354 14.0339 0.0340638 56.699 1 75.1298 0.000426544 105.21 0 0 0.999028 30.1212 3.91429E-06 143.05 0.999994 52.674 2.7741E-05 127.98 1 S HCKRYRSPEPDPY CAMK2;PKA;Proline-directed 0.003024 3.91429E-06 143.05 _pSPEPDPYLSYR_ S(1)PEPDPYLSYR S(75.13)PEPDPY(-75.13)LS(-75.13)Y(-75.13)R 1 2 702.29758 0.58806 42419000 4832100 292790 0 28526000 0 4865400 3902700 795 602 283 283 5819 6635 57374 34946 Mix4_TiO2_Reinj_1_5 3407 57372 34944 Mix4_TiO2_Reinj_1_3 3328 P49761;P49761-1;P49761-3 P49761 P49761 >sp|P49761|CLK3_HUMAN Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3 PE=1 SV=3;>sp|P49761-1|CLK3_HUMAN Isoform Long of Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3;>sp|P49761-3|CLK3_HUMAN Isoform 3 of Dual specificity protein 1 10.6426 1 49.8173 0.0593035 49.817 1 10.6426 0.00546907 78.641 0 0 0 0 1 S SKRSSRSVEDDKE CK1;CK2 0.081 0.00546907 78.641 _pSVEDDKEGHLVCR_ S(1)VEDDKEGHLVCR S(10.64)VEDDKEGHLVCR 1 3 541.89927 -0.11359 1657900 122310 0 0 1535600 0 0 0 796 603 366 366 90 106 1021 651 Mix4_TiO2_1_6 4791 1021 651 Mix4_TiO2_1_6 4791 P49768;P49768-2 P49768 P49768 >sp|P49768|PSN1_HUMAN Presenilin-1 OS=Homo sapiens GN=PSEN1 PE=1 SV=1;>sp|P49768-2|PSN1_HUMAN Isoform I-463 of Presenilin-1 OS=Homo sapiens GN=PSEN1 0.496743 0 0.496743 0 0.0155612 65.141 0 0 1 S AVQELSSSILAGE 0.0155612 65.141 _AAVQELSpSSILAGEDPEER_ AAVQELS(0.007)S(0.497)S(0.497)ILAGEDPEER AAVQELS(-18.82)S(0)S(0)ILAGEDPEER 8 2 1040.9754 0.0055597 0 0 0 0 0 0 0 0 797 603 367 367 90 106 1021 651 Mix4_TiO2_1_6 4791 1021 651 Mix4_TiO2_1_6 4791 P49768;P49768-2 P49768 P49768 >sp|P49768|PSN1_HUMAN Presenilin-1 OS=Homo sapiens GN=PSEN1 PE=1 SV=1;>sp|P49768-2|PSN1_HUMAN Isoform I-463 of Presenilin-1 OS=Homo sapiens GN=PSEN1 0.496743 0 0.496743 0 0.0155612 65.141 0 0 1 S VQELSSSILAGED NEK6 0.076 0.0155612 65.141 _AAVQELSpSSILAGEDPEER_ AAVQELS(0.007)S(0.497)S(0.497)ILAGEDPEER AAVQELS(-18.82)S(0)S(0)ILAGEDPEER 9 2 1040.9754 0.0055597 0 0 0 0 0 0 0 0 798 606 955 955 1978 2238 18038 10780 Mix4_TiO2_Reinj_1_1 5907 18038 10780 Mix4_TiO2_Reinj_1_1 5907 P49792 P49792 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2 PE=1 SV=2 0.999951 43.0868 0.999869 38.8195 0.0136629 66.64 0.999951 43.0868 0.0116836 70.19 0 0 1 S PATGILSPRGDDY CDK1;CK1;Proline-directed 0.0057 0.0116836 70.19 _FESPATGILpSPR_ FESPATGILS(1)PR FES(-70.19)PAT(-43.09)GILS(43.09)PR 10 2 677.82377 0.15114 165320 32373 0 0 132950 0 0 0 799 606 781 781 2663;3930 3030;4475;4476 24859 15382 Mix4_TiO2_Reinj_1_1 1162 37294 22931 Mix4_InSol_TiO2_1 3253 P49792 P49792 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2 PE=1 SV=2 0.999111 30.5547 0.942318 16.9028 0.671979 16.903 0 0 0.999111 30.5547 0.0214884 60.657 0 0 0.759738 6.65436 0.000751945 94.342 0 0 1 S IKHSTPSPTRYSL CDK1;CDK2;CK1;Proline-directed 0.0057 0.000751945 94.342 _HSTPpSPTR_ HSTPS(0.999)PT(0.001)R HS(-60.66)T(-50.32)PS(30.55)PT(-30.55)R 5 2 481.70821 -0.073475 239840 19265 0 0 70536 0 150040 0 800 606 1509 1509 3192 3622 30304 18852 Mix4_TiO2_1_1 5168 30304 18852 Mix4_TiO2_1_1 5168 P49792 P49792 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2 PE=1 SV=2 0.947788 14.1832 0.947788 14.1832 0.0882609 50.567 0.177893 -2.62334 1.25587 5.8004 0 0 0 0 1 S QNPRKQSLPATSI AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.004788 0.0882609 50.567 _KQpSLPATSIPTPASFK_ KQS(0.948)LPAT(0.036)S(0.016)IPTPASFK KQS(14.18)LPAT(-14.18)S(-17.73)IPT(-43.16)PAS(-50.57)FK 3 2 876.95023 0.29085 36655 36655 0 0 0 0 0 0 801 606 1514 1514 3192 3622 30305 18853 Mix4_TiO2_Reinj_1_1 5877 30304 18852 Mix4_TiO2_1_1 5168 P49792 P49792 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2 PE=1 SV=2 0.325457 0 0.0159845 -17.7301 0.0882609 50.567 0.325457 0 1.25587 5.8004 0 0 0 0 1 S QSLPATSIPTPAS 0.0882609 50.567 _KQSLPApTSIPTPASFK_ KQS(0.178)LPAT(0.325)S(0.325)IPT(0.086)PAS(0.086)FK KQS(-2.62)LPAT(0)S(0)IPT(-5.8)PAS(-5.8)FK 8 3 584.96924 -0.34672 0 0 0 0 0 0 0 0 802 606 2900 2900 6406 7328 64694 39684 Mix4_TiO2_Reinj_1_1 7605 64694 39684 Mix4_TiO2_Reinj_1_1 7605 P49792 P49792 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2 PE=1 SV=2 1 89.8515 1 80.9827 1.24469E-07 102.25 0 0 1 89.8515 7.92256E-08 108.04 0 0 1 S GEDEDGSDEEVVH CK2 0.117 7.92256E-08 108.04 _VGEDEDGpSDEEVVHNEDIHFEPIVSLPEVEVK_ VGEDEDGS(1)DEEVVHNEDIHFEPIVSLPEVEVK VGEDEDGS(89.85)DEEVVHNEDIHFEPIVS(-89.85)LPEVEVK 8 3 1224.2155 0.61953 2378700 540160 0 0 1838500 0 0 0 803 608 1420 1420 5642 6428 55106 33719 Mix4_TiO2_Reinj_1_5 5481 55106 33719 Mix4_TiO2_Reinj_1_5 5481 P49815;P49815-4;P49815-2;P49815-3;P49815-5;P49815-6 P49815 P49815 >sp|P49815|TSC2_HUMAN Tuberin OS=Homo sapiens GN=TSC2 PE=1 SV=2;>sp|P49815-4|TSC2_HUMAN Isoform 4 of Tuberin OS=Homo sapiens GN=TSC2;>sp|P49815-2|TSC2_HUMAN Isoform 2 of Tuberin OS=Homo sapiens GN=TSC2;>sp|P49815-3|TSC2_HUMAN Isoform 3 of Tuberin OS=Homo s 0.59287 1.63231 0 0 0.59287 1.63231 4.9397E-39 208.21 1 S VKARSQSGTLDGE CAMK2;PKA/AKT 0.00111111 4.9397E-39 208.21 _SQpSGTLDGESAAWSASGEDSR_ S(0.407)QS(0.593)GTLDGESAAWSASGEDSR S(-1.63)QS(1.63)GT(-50.7)LDGES(-130.68)AAWS(-186.64)AS(-208.21)GEDS(-208.21)R 3 2 1089.4346 0.24268 202600 0 0 0 202600 0 0 0 804 609 20 20 473;6241 537;7130 61906 37514 Mix4_TiO2_2_4 3075 61901 37507 Mix4_TiO2_1_4 3231 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.491155 0.858513 0.333333 0 4.20028E-27 158.45 0.491155 0.858513 1.57093E-05 98.08 0.436247 0.787337 1.26802E-19 152.38 0 0 0.333333 0 2.29096E-19 148.91 0.333333 0 3.08254E-19 146.23 1 S SGRARTSSFAEPG PKA 0.042 4.20028E-27 158.45 _TpSSFAEPGGGGGGGGGGPGGSASGPGGTGGGK_ T(0.403)S(0.491)S(0.106)FAEPGGGGGGGGGGPGGSASGPGGTGGGK T(-0.86)S(0.86)S(-6.67)FAEPGGGGGGGGGGPGGS(-91.81)AS(-91.81)GPGGT(-91.81)GGGK 2 3 838.34901 0.031801 0 0 0 0 0 0 0 0 0 805 609 21 21 473;6241 537;7130 61900 37504 Mix4_TiO2_1_4 3153 61901 37507 Mix4_TiO2_1_4 3231 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.747986 7.735 0.747986 7.735 4.20028E-27 158.45 0.722902 7.17476 1.57093E-05 98.08 0.342405 0 1.26802E-19 152.38 0 0 0.64563 5.61557 2.29096E-19 148.91 0.658948 3.90684 3.08254E-19 146.23 1 S GRARTSSFAEPGG CAMK2;CK2;PKA/AKT 0.001764 4.20028E-27 158.45 _TSpSFAEPGGGGGGGGGGPGGSASGPGGTGGGK_ T(0.126)S(0.126)S(0.748)FAEPGGGGGGGGGGPGGSASGPGGTGGGK T(-7.73)S(-7.73)S(7.73)FAEPGGGGGGGGGGPGGS(-101.49)AS(-111.92)GPGGT(-122.8)GGGK 3 3 838.34901 -0.45932 5869300 0.39212 4520100 49674 0 0 0 98783 1200700 806 609 39 39 473;6241 537;7130 61914 37524 Mix4_TiO2_Reinj_1_4 3892 61901 37507 Mix4_TiO2_1_4 3231 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.71102 5.5415 0.0251784 -11.8568 4.20028E-27 158.45 3.23744E-10 -91.8102 1.57093E-05 98.08 0.71102 5.5415 1.26802E-19 152.38 0 0 0.00550619 -17.7479 2.29096E-19 148.91 0.000108965 -34.8545 3.08254E-19 146.23 1 S GGGPGGSASGPGG 4.20028E-27 158.45 _TSSFAEPGGGGGGGGGGPGGpSASGPGGTGGGK_ T(0.001)S(0.001)S(0.003)FAEPGGGGGGGGGGPGGS(0.711)AS(0.198)GPGGT(0.085)GGGK T(-29.27)S(-28.8)S(-23.43)FAEPGGGGGGGGGGPGGS(5.54)AS(-5.54)GPGGT(-9.2)GGGK 21 2 1257.0199 0.56195 324330 0.021668 0 0 0 324330 0 0 0 807 609 41 41 473;6241 537;7130 61913 37523 Mix4_TiO2_Reinj_1_4 3867 61901 37507 Mix4_TiO2_1_4 3231 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.476724 0 0.0251784 -11.8568 4.20028E-27 158.45 3.23744E-10 -91.8102 1.57093E-05 98.08 0.476724 0 1.26802E-19 152.38 0 0 0.00550619 -17.7479 2.29096E-19 148.91 0.000108965 -34.8545 3.08254E-19 146.23 1 S GPGGSASGPGGTG 4.20028E-27 158.45 _TSSFAEPGGGGGGGGGGPGGpSASGPGGTGGGK_ TSSFAEPGGGGGGGGGGPGGS(0.477)AS(0.477)GPGGT(0.046)GGGK T(-42.5)S(-42.5)S(-42.5)FAEPGGGGGGGGGGPGGS(0)AS(0)GPGGT(-10.11)GGGK 23 3 838.34901 0.17692 0 0 0 0 0 0 0 0 0 808 609;610 278;215 278 2174;4645 2460;2461;5271 19964 12267 Mix4_TiO2_1_4 9014 19937 12184 Mix4_InSol_TiO2_1 5014 P49840;P49841-2;P49841 P49840;P49841-2 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2;>sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens 0.986891 18.8755 0.986891 18.8755 0.00243643 109.37 0.827838 6.82007 0.00253535 85.244 0.355228 -2.58898 0.00297666 114.47 0.567035 1.17596 0.15316 34.34 0.970369 15.7815 0.000140081 145.28 0.937283 11.8363 0.000945782 132.99 1 S RGEPNVSYICSRY GSK3 0.081 0.000140081 145.28 _GEPNVpSYICSR_ GEPNVS(0.987)Y(0.013)ICSR GEPNVS(18.88)Y(-18.88)ICS(-34.85)R 6 2 681.28141 -0.02427 824080 3.1317 56518 233510 0 0 34594 109870 389580 809 609;610 282;219 282 2174;4645 2460;2461;5271 19933 12180 Mix4_TiO2_Reinj_1_4 4273 19932 12178 Mix4_TiO2_1_4 3803 P49840;P49841-2;P49841 P49840;P49841-2 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2;>sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens 1 66.2913 0.999999 60.2023 0.00291066 81.067 0.00527531 -21.7316 0.00253535 85.244 1 66.2913 0.00842625 66.291 0.000436612 -31.1351 0.15316 34.34 0.990056 19.7658 0.341701 19.766 0.238298 -3.41717 0.000945782 132.99 2 S NVSYICSRYYRAP CK1 0.143 0.00291066 81.067 _GEPNVSpYICpSR_ GEPNVS(0.041)Y(0.959)ICS(1)R GEPNVS(-13.68)Y(13.68)ICS(66.29)R 10 2 721.26457 -0.23938 288740 1.0973 79069 0 0 193970 0 15697 0 810 609 2 2 5300 6034 51478 31517 Mix4_TiO2_Reinj_1_4 2007 51478 31517 Mix4_TiO2_Reinj_1_4 2007 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.889541 9.34527 0.217519 -5.49651 0.723541 18.334 0.889541 9.34527 0.0538644 55.028 1 S _____MSGGGPSG 0.0538644 55.028 _(ac)pSGGGPSGGGPGGSGR_ S(0.89)GGGPS(0.103)GGGPGGS(0.007)GR S(9.35)GGGPS(-9.35)GGGPGGS(-21.02)GR 1 2 633.24896 0.30752 272450 1.0961 0 0 0 272450 0 0 0 811 609 7 7 5300 6034 51477 31513 Mix4_TiO2_1_4 1488 51478 31517 Mix4_TiO2_Reinj_1_4 2007 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.771165 5.49651 0.771165 5.49651 0.723541 18.334 0.103428 -9.34527 0.0538644 55.028 1 S MSGGGPSGGGPGG 0.0538644 55.028 _(ac)SGGGPpSGGGPGGSGR_ S(0.218)GGGPS(0.771)GGGPGGS(0.011)GR S(-5.5)GGGPS(5.5)GGGPGGS(-18.33)GR 6 2 633.24896 0.17695 67188 0.2703 67188 0 0 0 0 0 0 812 609 483 483 5542 6316 54234 33213 Mix4_TiO2_1_4 6333 54234 33213 Mix4_TiO2_1_4 6333 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.683581 6.53469 0.683581 6.53469 3.52454E-07 114.05 0 0 0.628272 5.25352 0.983444 50.251 1 S PTLTNSS______ 3.52454E-07 114.05 _SPAGTTTLTPSSQALTETPTSSDWQSTDATPTLTNSpS_ SPAGTTTLTPSSQALTETPTSSDWQSTDAT(0.001)PT(0.012)LT(0.152)NS(0.152)S(0.684) S(-104.61)PAGT(-104.54)T(-106.01)T(-106.01)LT(-104.06)PS(-102.59)S(-102.59)QALT(-98.28)ET(-83.22)PT(-63.08)S(-52.56)S(-47.05)DWQS(-38.63)T(-38.63)DAT(-29.05)PT(-17.66)LT(-6.53)NS(-6.53)S(6.53) 37 3 1273.9038 -1.0543 1728200 0.0086028 1443000 0 0 0 0 0 285180 813 610 402 402 2868;2869 3266;3268 27314 17067 Mix4_TiO2_1_5 2805 27315 17068 Mix4_TiO2_Reinj_1_4 3234 P49841-2;P49841 P49841-2 P49841-2 >sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 0.466974 0 0.466974 0 5.33725E-24 163.83 0 0 0.0159566 -17.8995 8.6388E-33 187.8 0.127675 -7.45021 8.15592E-17 144.73 0.458307 0 3.80187E-17 151.08 1 S RIQAAASTPTNAT 8.6388E-33 187.8 _IQAAApSTPTNATAASDANTGDR_ IQAAAS(0.467)T(0.467)PT(0.066)NATAASDANTGDR IQAAAS(0)T(0)PT(-8.5)NAT(-35.67)AAS(-72.19)DANT(-90.19)GDR 6 2 1092.4819 0.21136 0 0 0 0 0 0 0 0 0 814 610 9 9 6265 7156;7157 62423 37971 Mix4_InSol_TiO2_1 6144 62407 37966 Mix4_InSol_Tio2_Reinj_1 5286 P49841-2;P49841 P49841-2 P49841-2 >sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 0.742282 7.23552 0.358084 0 0.000520744 80.788 0.715454 6.6282 0.002624 77.115 0.742282 7.23552 0.000233994 90.75 0.357788 0 2.55026E-05 97.975 1 S GRPRTTSFAESCK CAMK2;CK2;GSK3;PKA/AKT 0.001764 2.55026E-05 97.975 _TTpSFAESCKPVQQPSAFGSMK_ T(0.117)T(0.14)S(0.742)FAESCKPVQQPSAFGSMK T(-8.03)T(-7.24)S(7.24)FAES(-31.76)CKPVQQPS(-53.68)AFGS(-53.68)MK 3 3 790.01649 -0.27853 4763300 0 0 0 2017500 0 2745900 0 815 611 171 171 1185 1331 11131 6825 Mix4_TiO2_Reinj_1_4 5296 11131 6825 Mix4_TiO2_Reinj_1_4 5296 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.857659 7.92755 0.598973 5.54796 0.622634 25.923 0.857659 7.92755 0.124469 45.721 0.506433 7.89327 0.839654 19.179 0.553575 1.06795 0.708968 23.108 1 S THYRPVSASRSSL CAMK2;GSK3 0.042 0.124469 45.721 _DSAYQSITHYRPVpSASR_ DSAYQSITHY(0.003)RPVS(0.858)AS(0.138)R DS(-45.72)AY(-45.72)QS(-34.21)IT(-34.21)HY(-23.98)RPVS(7.93)AS(-7.93)R 14 3 673.3091 0.037122 4458400 97.056 142780 0 0 3266000 0 943770 105860 816 611 173 173 1185 1331 11124 6817 Mix4_InSol_TiO2_1 5811 11131 6825 Mix4_TiO2_Reinj_1_4 5296 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.889107 11.9166 0.082492 -8.60996 0.622634 25.923 0.511 0.213246 0.124469 45.721 0.889107 11.9166 0.839654 19.179 0.432894 -1.06795 0.708968 23.108 1 S YRPVSASRSSLDL 0.124469 45.721 _DSAYQSITHYRPVSApSR_ DS(0.011)AY(0.011)QS(0.011)IT(0.011)HY(0.011)RPVS(0.057)AS(0.889)R DS(-19.18)AY(-19.18)QS(-19.18)IT(-19.18)HY(-19.18)RPVS(-11.92)AS(11.92)R 16 2 1009.46 -0.45655 755640 16.45 0 0 0 550110 0 205530 0 817 611 8 8 3826 4324 36328 22427 Mix4_TiO2_Reinj_1_2 7487 36328 22427 Mix4_TiO2_Reinj_1_2 7487 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.98465 18.0718 0 0 0.98465 18.0718 9.07546E-13 146.4 1 S DNYADLSDTELTT CK2 0.117 9.07546E-13 146.4 _(ac)M(ox)DNYADLpSDTELTTLLR_ MDNYADLS(0.985)DT(0.015)ELTTLLR MDNY(-79.91)ADLS(18.07)DT(-18.07)ELT(-70.55)T(-103.6)LLR 8 2 1054.9583 -0.62078 114230 0 0 0 114230 0 0 0 818 611 49 49 4953;5026 5631;5717 47671 29130 Mix4_TiO2_Reinj_1_2 5417 47670 29127 Mix4_TiO2_Reinj_1_2 5388 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.99951 33.1166 0.94429 13.3236 1.72501E-11 131.56 0.99951 33.1166 9.02925E-18 155.35 0 0 0 0 1 S TQRRRLSPPSSSA CAMK2;GSK3;PKA;Proline-directed 0.004788 9.02925E-18 155.35 _RLpSPPSSSAASSYSFSDLNSTR_ RLS(1)PPSSSAASSYSFSDLNSTR RLS(33.12)PPS(-33.12)S(-55.87)S(-71.16)AAS(-94.82)S(-97.83)Y(-112.99)S(-124.72)FS(-133.6)DLNS(-135.08)T(-135.08)R 3 2 1199.0396 0.073652 4032400 1066100 0 0 2966300 0 0 0 819 611 52 52 4953;5026 5631;5717 47672 29131 Mix4_TiO2_Reinj_1_4 6194 47670 29127 Mix4_TiO2_Reinj_1_2 5388 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.330534 0 0.295801 0 1.72501E-11 131.56 0.330534 0 9.02925E-18 155.35 0 0 0 0 1 S RRLSPPSSSAASS CK1 0.081 9.02925E-18 155.35 _RLSPPpSSSAASSYSFSDLNSTR_ RLS(0.002)PPS(0.331)S(0.331)S(0.331)AAS(0.006)SYSFSDLNSTR RLS(-22.27)PPS(0)S(0)S(0)AAS(-17.12)S(-40.38)Y(-57.33)S(-73.82)FS(-91.34)DLNS(-145.72)T(-145.72)R 6 3 799.69546 -0.05848 0 0 0 0 0 0 0 0 820 611 53 53 4953;5026 5631;5717 47672 29131 Mix4_TiO2_Reinj_1_4 6194 47670 29127 Mix4_TiO2_Reinj_1_2 5388 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.330534 0 0.295801 0 1.72501E-11 131.56 0.330534 0 9.02925E-18 155.35 0 0 0 0 1 S RLSPPSSSAASSY CK1;GSK3 0.081 9.02925E-18 155.35 _RLSPPpSSSAASSYSFSDLNSTR_ RLS(0.002)PPS(0.331)S(0.331)S(0.331)AAS(0.006)SYSFSDLNSTR RLS(-22.27)PPS(0)S(0)S(0)AAS(-17.12)S(-40.38)Y(-57.33)S(-73.82)FS(-91.34)DLNS(-145.72)T(-145.72)R 7 3 799.69546 -0.05848 0 0 0 0 0 0 0 0 821 611 54 54 4953;5026 5631;5717 47672 29131 Mix4_TiO2_Reinj_1_4 6194 47670 29127 Mix4_TiO2_Reinj_1_2 5388 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.330534 0 0.295801 0 1.72501E-11 131.56 0.330534 0 9.02925E-18 155.35 0 0 0 0 1 S LSPPSSSAASSYS GSK3 0.081 9.02925E-18 155.35 _RLSPPpSSSAASSYSFSDLNSTR_ RLS(0.002)PPS(0.331)S(0.331)S(0.331)AAS(0.006)SYSFSDLNSTR RLS(-22.27)PPS(0)S(0)S(0)AAS(-17.12)S(-40.38)Y(-57.33)S(-73.82)FS(-91.34)DLNS(-145.72)T(-145.72)R 8 3 799.69546 -0.05848 0 0 0 0 0 0 0 0 822 611 57 57 4953;5026 5631;5717 47669 29124 Mix4_TiO2_1_6 4598 47670 29127 Mix4_TiO2_Reinj_1_2 5388 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.245327 0 0.245327 0 1.72501E-11 131.56 0.00640797 -17.125 9.02925E-18 155.35 0 0 0 0 1 S PSSSAASSYSFSD CK1 0.081 9.02925E-18 155.35 _RLSPPSSpSAASSYSFSDLNSTR_ RLS(0.069)PPS(0.069)S(0.069)S(0.245)AAS(0.245)S(0.245)Y(0.057)S(0.001)FSDLNSTR RLS(-5.53)PPS(-5.53)S(-5.53)S(0)AAS(0)S(0)Y(-6.31)S(-26.32)FS(-33)DLNS(-41.68)T(-41.68)R 11 3 799.69546 -0.48577 0 0 0 0 0 0 0 0 823 611 58 58 4953;5026 5631;5717 47669 29124 Mix4_TiO2_1_6 4598 47670 29127 Mix4_TiO2_Reinj_1_2 5388 P50402 P50402 P50402 >sp|P50402|EMD_HUMAN Emerin OS=Homo sapiens GN=EMD PE=1 SV=1 0.245327 0 0.245327 0 1.72501E-11 131.56 3.02796E-05 -40.3807 9.02925E-18 155.35 0 0 0 0 1 S SSSAASSYSFSDL CK1;GSK3 0.081 9.02925E-18 155.35 _RLSPPSSpSAASSYSFSDLNSTR_ RLS(0.069)PPS(0.069)S(0.069)S(0.245)AAS(0.245)S(0.245)Y(0.057)S(0.001)FSDLNSTR RLS(-5.53)PPS(-5.53)S(-5.53)S(0)AAS(0)S(0)Y(-6.31)S(-26.32)FS(-33)DLNS(-41.68)T(-41.68)R 12 3 799.69546 -0.48577 0 0 0 0 0 0 0 0 824 613 759 759 1398 1571 13060 8041 Mix4_TiO2_Reinj_1_3 8788 13054 8027 Mix4_TiO2_1_3 8154 P50570;P50570-2 P50570 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DNM2 PE=1 SV=2;>sp|P50570-2|DYN2_HUMAN Isoform 2 of Dynamin-2 OS=Homo sapiens GN=DNM2 0.363804 0 0.166421 0 2.04483E-17 138.96 0 0 0.363804 0 5.33404E-11 119.67 0 0 0 0 1 S DDTWLQSASSHSP CK1 0.143 2.04483E-17 138.96 _EALNIIGDISTSTVSTPVPPPVDDTWLQpSASSHSPTPQR_ EALNIIGDISTSTVS(0.001)T(0.001)PVPPPVDDT(0.022)WLQS(0.364)AS(0.364)S(0.083)HS(0.083)PT(0.083)PQR EALNIIGDIS(-31.73)T(-31.73)S(-31.73)T(-31.73)VS(-27.51)T(-27.51)PVPPPVDDT(-12.24)WLQS(0)AS(0)S(-6.43)HS(-6.43)PT(-6.43)PQR 29 6 697.67397 -0.22012 0 0 0 0 0 0 0 0 825 613 761 761 1398 1571 13060 8041 Mix4_TiO2_Reinj_1_3 8788 13054 8027 Mix4_TiO2_1_3 8154 P50570;P50570-2 P50570 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DNM2 PE=1 SV=2;>sp|P50570-2|DYN2_HUMAN Isoform 2 of Dynamin-2 OS=Homo sapiens GN=DNM2 0.363804 0 0.300263 0 2.04483E-17 138.96 0 0 0.363804 0 5.33404E-11 119.67 0 0 0 0 1 S TWLQSASSHSPTP 2.04483E-17 138.96 _EALNIIGDISTSTVSTPVPPPVDDTWLQpSASSHSPTPQR_ EALNIIGDISTSTVS(0.001)T(0.001)PVPPPVDDT(0.022)WLQS(0.364)AS(0.364)S(0.083)HS(0.083)PT(0.083)PQR EALNIIGDIS(-31.73)T(-31.73)S(-31.73)T(-31.73)VS(-27.51)T(-27.51)PVPPPVDDT(-12.24)WLQS(0)AS(0)S(-6.43)HS(-6.43)PT(-6.43)PQR 31 6 697.67397 -0.22012 0 0 0 0 0 0 0 0 826 613 762 762 1398 1571 13057 8034 Mix4_TiO2_1_5 7879 13054 8027 Mix4_TiO2_1_3 8154 P50570;P50570-2 P50570 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DNM2 PE=1 SV=2;>sp|P50570-2|DYN2_HUMAN Isoform 2 of Dynamin-2 OS=Homo sapiens GN=DNM2 0.374649 0 0.374649 0 2.04483E-17 138.96 0 0 0.33733 0 5.33404E-11 119.67 0 0 0 0 1 S WLQSASSHSPTPQ CK1 0.081 2.04483E-17 138.96 _EALNIIGDISTSTVSTPVPPPVDDTWLQSASpSHSPTPQR_ EALNIIGDISTSTVSTPVPPPVDDT(0.001)WLQS(0.036)AS(0.115)S(0.375)HS(0.375)PT(0.099)PQR EALNIIGDIS(-69.36)T(-67.36)S(-67.36)T(-67.36)VS(-67.75)T(-56.59)PVPPPVDDT(-25.12)WLQS(-10.17)AS(-5.14)S(0)HS(0)PT(-5.79)PQR 32 3 1394.3407 -0.22585 0 0 0 0 0 0 0 0 827 613 764 764 1398 1571 13057 8034 Mix4_TiO2_1_5 7879 13054 8027 Mix4_TiO2_1_3 8154 P50570;P50570-2 P50570 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DNM2 PE=1 SV=2;>sp|P50570-2|DYN2_HUMAN Isoform 2 of Dynamin-2 OS=Homo sapiens GN=DNM2 0.374649 0 0.374649 0 2.04483E-17 138.96 0 0 0.247412 -0.405357 5.33404E-11 119.67 0 0 0 0 1 S QSASSHSPTPQRR CK1;Proline-directed 0.05 2.04483E-17 138.96 _EALNIIGDISTSTVSTPVPPPVDDTWLQSASpSHSPTPQR_ EALNIIGDISTSTVSTPVPPPVDDT(0.001)WLQS(0.036)AS(0.115)S(0.375)HS(0.375)PT(0.099)PQR EALNIIGDIS(-69.36)T(-67.36)S(-67.36)T(-67.36)VS(-67.75)T(-56.59)PVPPPVDDT(-25.12)WLQS(-10.17)AS(-5.14)S(0)HS(0)PT(-5.79)PQR 34 3 1394.3407 -0.22585 0 0 0 0 0 0 0 0 828 614 161 161 5266;5267 5994;5995 51122 31341 Mix4_InSol_TiO2_3 2594 51124 31345 Mix4_InSol_Tio2_Reinj_1 4641 P50613 P50613 P50613 >sp|P50613|CDK7_HUMAN Cell division protein kinase 7 OS=Homo sapiens GN=CDK7 PE=1 SV=1 0.707678 7.56003 0.25054 -4.75871 0.103021 54.297 0.442165 -1.00922 0.913469 7.088 0.0191062 -17.1045 0.174604 41.735 0.707678 7.56003 7.85565E-06 107.13 0.496961 0 1.18723E-06 116.44 2 S DFGLAKSFGSPNR NEK6 0.076 1.18723E-06 116.44 _pSFGSPNRAYpTHQVVTR_ S(0.708)FGS(0.217)PNRAY(0.15)T(0.774)HQVVT(0.15)R S(7.56)FGS(-7.56)PNRAY(-11.99)T(11.99)HQVVT(-11.99)R 1 2 990.42987 0.27658 273960 0 0 0 0 0 273960 0 829 614 164 164 5266;5267 5994;5995 51099 31293 Mix4_TiO2_1_2 1682 51099 31293 Mix4_TiO2_1_2 1682 P50613 P50613 P50613 >sp|P50613|CDK7_HUMAN Cell division protein kinase 7 OS=Homo sapiens GN=CDK7 PE=1 SV=1 0.999996 54.2967 0.999996 54.2967 0.103021 54.297 0.836453 7.08799 0.913469 7.088 0.999933 41.7352 0.174604 41.735 0.999983 47.7287 0.140449 47.729 0.999979 46.7809 0.145851 46.781 1 S LAKSFGSPNRAYT CDK1;CDK2;CK1;Proline-directed 0.0057 0.103021 54.297 _SFGpSPNR_ SFGS(1)PNR S(-54.3)FGS(54.3)PNR 4 2 422.67109 -0.18392 13913000 2083400 89245 0 10368000 0 745490 626220 830 615 1034 1034 2606 2966 24378 15133 Mix4_TiO2_Reinj_1_5 4266 24378 15133 Mix4_TiO2_Reinj_1_5 4266 P50748 P50748 P50748 >sp|P50748|KNTC1_HUMAN Kinetochore-associated protein 1 OS=Homo sapiens GN=KNTC1 PE=1 SV=1 0.774466 5.35791 0 0 0.774466 5.35791 0.12519 42.189 0.5 0 0.602348 21.928 0 0 1 S AKHKPGSTPEPIA CK2 0.117 0.12519 42.189 _HKPGpSTPEPIAAEVR_ HKPGS(0.774)T(0.226)PEPIAAEVR HKPGS(5.36)T(-5.36)PEPIAAEVR 5 3 556.94169 -0.57361 279600 0 0 0 247480 0 32114 0 831 616 145 145 6197 7079 61413 37232 Mix4_InSol_TiO2_1 2227 61413 37232 Mix4_InSol_TiO2_1 2227 P50749 P50749 P50749 >sp|P50749|RASF2_HUMAN Ras association domain-containing protein 2 OS=Homo sapiens GN=RASSF2 PE=1 SV=1 0.999233 31.1484 0.991398 20.6163 0.111104 46.506 0 0 0.992784 21.3857 0.0796807 51.339 0.999233 31.1484 0.00561555 81.613 0.994505 22.5763 0.0075764 77.596 1 S QLMRTRSDVGVRR CAMK2;CHK1;CHK1/2;PKD 0.003192 0.00561555 81.613 _TRpSDVGVR_ T(0.001)RS(0.999)DVGVR T(-31.15)RS(31.15)DVGVR 3 2 485.22931 0.86079 758980 27789 0 0 558630 0 77240 95325 832 617 464 464 2461;3050;4925 2793;3469;5599 29108 18200 Mix4_TiO2_Reinj_1_4 2125 23141 14440 Mix4_TiO2_Reinj_1_4 2044 P50750-2;P50750 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9;>sp|P50750|CDK9_HUMAN Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 PE=1 SV=3 1 79.5068 1 80.5446 6.75054E-09 145.78 1 79.5068 1.9584E-09 171.79 0.999526 33.2581 2.65593E-05 112.75 0.999987 49.0332 5.83628E-05 106.19 1 S PPRRKGSQITQQS CAMK2;PKA 0.004788 1.9584E-09 171.79 _KGpSQITQQSTNQSR_ KGS(1)QITQQSTNQSR KGS(79.51)QIT(-79.51)QQS(-101.92)T(-100.75)NQS(-134.26)R 3 2 821.88086 0.34555 4143600 1.6011 373640 0 0 2823000 0 362470 584540 833 617 470 470 2461;3050;4925 2793;3469;5599 23141 14440 Mix4_TiO2_Reinj_1_4 2044 23141 14440 Mix4_TiO2_Reinj_1_4 2044 P50750-2;P50750 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9;>sp|P50750|CDK9_HUMAN Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 PE=1 SV=3 0.990932 20.3856 6.12695E-07 -62.0232 6.75054E-09 145.78 0.990932 20.3856 1.9584E-09 171.79 2.74348E-05 -45.6122 2.65593E-05 112.75 4.0634E-07 -63.9061 5.83628E-05 106.19 1 S SQITQQSTNQSRN GSK3 0.081 1.9584E-09 171.79 _GSQITQQpSTNQSR_ GSQITQQS(0.991)T(0.009)NQSR GS(-95.03)QIT(-61.68)QQS(20.39)T(-20.39)NQS(-83.84)R 8 2 757.83338 0.96664 86757 0.033524 0 0 0 86757 0 0 0 834 617 52 52 3620 4080 34055 21022 Mix4_TiO2_1_4 5303 34057 21024 Mix4_TiO2_Reinj_1_4 5878 P50750-2 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 0.310075 0 0.310075 0 5.35417E-13 137.36 0.0323464 -13.481 1.89478E-24 161.44 0 0 0 0 1 S PAPPGLSGTTSPR GSK3 0.081 1.89478E-24 161.44 _LPAPPIGAAASSGGGGGGGSGGGGGGASAAPAPPGLpSGTTSPR_ LPAPPIGAAASSGGGGGGGSGGGGGGASAAPAPPGLS(0.31)GT(0.31)T(0.07)S(0.31)PR LPAPPIGAAAS(-130.41)S(-130.41)GGGGGGGS(-107.8)GGGGGGAS(-63.94)AAPAPPGLS(0)GT(0)T(-6.48)S(0)PR 37 4 870.41413 0.081062 0 0 0 0 0 0 0 0 835 617 56 56 3620 4080 34057 21024 Mix4_TiO2_Reinj_1_4 5878 34057 21024 Mix4_TiO2_Reinj_1_4 5878 P50750-2 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 0.907304 14.6781 0.472042 4.30079 5.35417E-13 137.36 0.907304 14.6781 1.89478E-24 161.44 0 0 0 0 1 S GLSGTTSPRGPGG CDK1;CK1;Proline-directed 0.0057 1.89478E-24 161.44 _LPAPPIGAAASSGGGGGGGSGGGGGGASAAPAPPGLSGTTpSPR_ LPAPPIGAAASSGGGGGGGSGGGGGGASAAPAPPGLS(0.031)GT(0.031)T(0.031)S(0.907)PR LPAPPIGAAAS(-157.51)S(-156.95)GGGGGGGS(-134.81)GGGGGGAS(-82.96)AAPAPPGLS(-14.68)GT(-14.68)T(-14.68)S(14.68)PR 41 4 870.41413 0.23206 6673800 0 0 0 6673800 0 0 0 836 618 1261 1261 3387 3828 31922 19743 Mix4_TiO2_Reinj_1_1 4094 31922 19743 Mix4_TiO2_Reinj_1_1 4094 P50851;P50851-2 P50851 P50851 >sp|P50851|LRBA_HUMAN Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens GN=LRBA PE=1 SV=4;>sp|P50851-2|LRBA_HUMAN Isoform 2 of Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens GN=LRBA 1 52.4719 0 0 1 52.4719 0.0760186 52.472 1 S RLELKASPNVEAP NEK6;Proline-directed 0.05 0.0760186 52.472 _LELKApSPNVEAPQPHR_ LELKAS(1)PNVEAPQPHR LELKAS(52.47)PNVEAPQPHR 6 3 622.64716 -0.30652 55590 0 0 0 55590 0 0 0 837 619 139 139 53 64 542 349 Mix4_TiO2_Reinj_1_6 3017 533 330 Mix4_InSol_TiO2_1 3834 P50914 P50914 P50914 >sp|P50914|RL14_HUMAN 60S ribosomal protein L14 OS=Homo sapiens GN=RPL14 PE=1 SV=4 1 59.0167 1 59.0167 0.0122211 59.017 1 20.0658 0.387406 20.066 1 59.0167 0.0122211 59.017 0 0 1 39.1221 0.00633611 65.33 1 8.75261 0.0687752 41.108 1 S AALLKASPKKAPG CDK1;CDK2;NEK6;Proline-directed 0.0057 0.00633611 65.33 _AALLKApSPK_ AALLKAS(1)PK AALLKAS(59.02)PK 7 2 489.77282 -0.3208 7876300 640570 117540 0 3050200 0 2127000 1941100 838 623 264 264 4431 5041 42140 25964 Mix4_TiO2_Reinj_1_5 1763 42140 25964 Mix4_TiO2_Reinj_1_5 1763 P51530;P51530-3;P51530-2 P51530 P51530 >sp|P51530|DNA2L_HUMAN DNA2-like helicase OS=Homo sapiens GN=DNA2 PE=1 SV=3;>sp|P51530-3|DNA2L_HUMAN Isoform 3 of DNA2-like helicase OS=Homo sapiens GN=DNA2;>sp|P51530-2|DNA2L_HUMAN Isoform 2 of DNA2-like helicase OS=Homo sapiens GN=DNA2 0.999998 58.0291 0 0 0.999998 58.0291 0.00942171 74.276 0 0 1 S PMDIEESIWSPRF PLK1 0.033462 0.00942171 74.276 _PMDIEEpSIWSPR_ PMDIEES(1)IWSPR PMDIEES(58.03)IWS(-58.03)PR 7 2 770.3311 -0.79707 557410 0 0 0 557410 0 0 0 839 624 1452 1452 2416 2738 22580 14088 Mix4_TiO2_Reinj_1_1 3934 22580 14088 Mix4_TiO2_Reinj_1_1 3934 P51532 P51532 P51532 >sp|P51532|SMCA4_HUMAN Transcription activator BRG1 OS=Homo sapiens GN=SMARCA4 PE=1 SV=2 1 69.3959 0 0 0 0 1 69.3959 0.00054338 93.694 0 0 0 0 1 S PPAEKLSPNPPNL Proline-directed 0.05 0.00054338 93.694 _GRPPAEKLpSPNPPNLTK_ GRPPAEKLS(1)PNPPNLTK GRPPAEKLS(69.4)PNPPNLT(-69.4)K 9 3 632.66281 0.35672 569580 0 0 0 569580 0 0 0 840 627 18 18 138 161;162;163 1445 905 Mix4_TiO2_Reinj_1_6 6130 1443 903 Mix4_TiO2_Reinj_1_6 5591 P51636;P51636-3 P51636 P51636 >sp|P51636|CAV2_HUMAN Caveolin-2 OS=Homo sapiens GN=CAV2 PE=1 SV=2;>sp|P51636-3|CAV2_HUMAN Isoform C of Caveolin-2 OS=Homo sapiens GN=CAV2 0.46023 0 0.177489 -6.26736 0.140273 54.626 0.46023 0 0.0151577 66.573 2 S LFMDDDSYSHHSG PLK1 0.033462 0.0151577 66.573 _ADVQLFMDDDpSpYSHHSGLEYADPEK_ ADVQLFMDDDS(0.46)Y(0.46)S(0.46)HHS(0.46)GLEY(0.159)ADPEK ADVQLFMDDDS(0)Y(0)S(0)HHS(0)GLEY(-5.47)ADPEK 11 3 1010.391 -0.0051504 0 0 0 0 0 0 0 0 841 627 20 20 138 161;162;163 1444 904 Mix4_TiO2_1_6 5324 1443 903 Mix4_TiO2_Reinj_1_6 5591 P51636;P51636-3 P51636 P51636 >sp|P51636|CAV2_HUMAN Caveolin-2 OS=Homo sapiens GN=CAV2 PE=1 SV=2;>sp|P51636-3|CAV2_HUMAN Isoform C of Caveolin-2 OS=Homo sapiens GN=CAV2 0.729501 7.72971 0.729501 7.72971 0.140273 54.626 0.46023 0 0.0151577 66.573 2 S MDDDSYSHHSGLE 0.0151577 66.573 _ADVQLFMDDDSYpSHHpSGLEYADPEK_ ADVQLFMDDDS(0.154)Y(0.154)S(0.73)HHS(0.794)GLEY(0.168)ADPEK ADVQLFMDDDS(-7.73)Y(-7.73)S(7.73)HHS(7.17)GLEY(-7.17)ADPEK 13 3 1010.391 -0.34204 117340 117340 0 0 0 0 0 0 842 627 23 23 138 161;162;163 1443 903 Mix4_TiO2_Reinj_1_6 5591 1443 903 Mix4_TiO2_Reinj_1_6 5591 P51636;P51636-3 P51636 P51636 >sp|P51636|CAV2_HUMAN Caveolin-2 OS=Homo sapiens GN=CAV2 PE=1 SV=2;>sp|P51636-3|CAV2_HUMAN Isoform C of Caveolin-2 OS=Homo sapiens GN=CAV2 0.9317 13.335 0.794442 7.17461 0.140273 54.626 0.9317 13.335 0.0151577 66.573 2 S DSYSHHSGLEYAD CK1;CK2 0.081 0.0151577 66.573 _ADVQLFM(ox)DDDpSYSHHpSGLEYADPEK_ ADVQLFMDDDS(0.335)Y(0.335)S(0.344)HHS(0.932)GLEY(0.054)ADPEK ADVQLFMDDDS(0)Y(0)S(0)HHS(13.34)GLEY(-13.34)ADPEK 16 3 1015.7226 0.031984 388400 117340 0 0 271060 0 0 0 843 629 712 712 4135 4707 39380 24235 Mix4_InSol_Tio2_Reinj_1 6205 39380 24235 Mix4_InSol_Tio2_Reinj_1 6205 P51788;P51788-3 P51788 P51788 >sp|P51788|CLCN2_HUMAN Chloride channel protein 2 OS=Homo sapiens GN=CLCN2 PE=1 SV=2;>sp|P51788-3|CLCN2_HUMAN Isoform 3 of Chloride channel protein 2 OS=Homo sapiens GN=CLCN2 0.962911 14.8967 0 0 0.962911 14.8967 0.0151333 67.595 1 S TRNLGESPTGSAE GSK3;NEK6;Proline-directed 0.05 0.0151333 67.595 _NLGEpSPTGSAESAGIALR_ NLGES(0.963)PT(0.031)GS(0.006)AESAGIALR NLGES(14.9)PT(-14.9)GS(-22.13)AES(-49.43)AGIALR 5 2 905.42256 1.6127 33378 0 0 0 0 0 0 33378 844 631;966;1767 227;221;232 227 644;2980 740;741;3389;3390 6172 3611 Mix4_TiO2_1_3 7250 6177 3622 Mix4_TiO2_Reinj_1_3 8007 P51812;Q15418;Q9UK32 P51812;Q15418;Q9UK32 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1;>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2;>sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Ho 1 76.4098 1 76.4098 3.93447E-26 189.68 0 0 1 81.096 1.73198E-39 232.03 0 0 1 73.0156 1.28114E-25 177.1 0.999996 54.6898 1.16935E-25 178.7 1 S HEKKAYSFCGTVE;QEKKAYSFCGTVE 1.73198E-39 232.03 _AYpSFCGTVEYMAPEVVNR_ AYS(1)FCGTVEYMAPEVVNR AY(-84.9)S(76.41)FCGT(-76.41)VEY(-147.81)MAPEVVNR 3 2 1086.9601 0.42162 21151000 1477300 0 0 12530000 0 4246500 2897000 845 631 369 369 1235;6141 1390;1391;7010;7011;7012 60763 36827 Mix4_TiO2_Reinj_1_3 5449 60763 36827 Mix4_TiO2_Reinj_1_3 5449 P51812 P51812 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1 0.999991 50.3768 0.999982 47.4216 0.00034243 93.051 0 0 0.999991 50.3768 8.5638E-16 148.64 0.991673 20.764 7.90244E-05 97.55 0.989096 22.5867 0.000646008 87.865 1 S AKTPKDSPGIPPS CK1;Proline-directed 0.05 8.5638E-16 148.64 _TPKDpSPGIPPSANAHQLFR_ TPKDS(1)PGIPPSANAHQLFR T(-50.38)PKDS(50.38)PGIPPS(-64.85)ANAHQLFR 5 2 1057.015 0.11483 27258000 4378600 0 0 18655000 0 2186500 2038300 846 631 375 375 1235;6141 1390;1391;7010;7011;7012 11594 7098 Mix4_TiO2_Reinj_1_3 5931 60806 36852 Mix4_TiO2_1_3 5689 P51812 P51812 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1 1 54.3591 1 13.5694 1.91635E-06 109.59 0 0 1 54.3591 0.011847 68.866 0.999851 37.4496 0.167962 42.122 0.0340661 -13.8403 0.000646008 87.865 2 S SPGIPPSANAHQL 1.91635E-06 109.59 _DpSPGIPPpSANAHQLFR_ DS(1)PGIPPS(1)ANAHQLFR DS(54.36)PGIPPS(54.36)ANAHQLFR 8 2 933.90042 -0.13993 14107000 734050 0 0 13074000 0 298510 0 847 631 737 737 3077 3498 29323 18292 Mix4_TiO2_Reinj_1_3 4736 29322 18291 Mix4_TiO2_1_3 3807 P51812 P51812 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1 0.837263 7.37028 0.80851 6.47258 0.0692938 60.215 0 0 0.837263 7.37028 0.257204 32.094 0.504944 3.09619 1.06796 3.0962 0.762546 8.07716 0.870168 8.2069 1 S GIKKITSTAL___ CHK1;PKD 0.020748 0.0692938 60.215 _KITpSTAL_ KIT(0.153)S(0.837)T(0.009)AL KIT(-7.37)S(7.37)T(-19.53)AL 4 2 407.20952 0.088129 364400 45774 0 0 202950 0 61116 54567 848 631 715 715 4278 4868 40703 25060 Mix4_TiO2_Reinj_1_6 3820 40700 25056 Mix4_TiO2_Reinj_1_3 4519 P51812 P51812 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1 1 29.7446 1 32.5282 0.00215123 106.68 1 37.2013 0.119727 37.201 1 29.7446 0.00215123 106.68 0 0 1 9.04126 0.00139581 97.929 1 14.0542 0.00159272 95.737 1 S ALNRNQSPVLEPV CAMK2;CHK1;CHK1/2;PKD;Proline-directed 0.003192 0.00215123 106.68 _NQpSPVLEPVGR_ NQS(1)PVLEPVGR NQS(29.74)PVLEPVGR 3 2 638.30828 0.3831 16225000 145 3196200 26268 0 8392500 0 2591900 2017900 849 631 415 415 4305 4897 40902 25164 Mix4_TiO2_1_3 5194 40902 25164 Mix4_TiO2_1_3 5194 P51812 P51812 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1 1 101.346 1 101.346 7.73706E-05 126.53 1 67.6495 0.00237136 94.405 1 S QQLHRNSIQFTDG AURORA;AURORA-1;PKA 0.020748 7.73706E-05 126.53 _NpSIQFTDGYEVK_ NS(1)IQFTDGYEVK NS(101.35)IQFT(-101.35)DGY(-126.53)EVK 2 2 740.82142 0.11353 6405300 162.38 1168400 0 0 5236900 0 0 0 850 631;966;1767 78;72;83 78 6472 7403 65422 40106 Mix4_TiO2_Reinj_1_3 4496 65422 40106 Mix4_TiO2_Reinj_1_3 4496 P51812;Q15418;Q9UK32 P51812;Q15418;Q9UK32 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1;>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2;>sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Ho 1 41.1122 0 0 1 41.1122 0.068763 41.112 1 S KVLGQGSFGKVFL 0.068763 41.112 _VLGQGpSFGK_ VLGQGS(1)FGK VLGQGS(41.11)FGK 6 2 486.73115 0.5885 41270 0 0 0 41270 0 0 0 851 632 165 165 219;220;4798 252;253;5448 45734 27971 Mix4_TiO2_Reinj_1_4 4318 45734 27971 Mix4_TiO2_Reinj_1_4 4318 P51858 P51858 P51858 >sp|P51858|HDGF_HUMAN Hepatoma-derived growth factor OS=Homo sapiens GN=HDGF PE=1 SV=1 1 39.7273 1 23.6645 0.369255 23.665 0 0 1 39.7273 0.0902139 39.727 0 0 1 17.0982 0.535 17.098 1 S GDLLEDSPKRPKE CDK1;CDK2;NEK6;Proline-directed 0.0057 0.0902139 39.727 _RAGDLLEDpSPK_ RAGDLLEDS(1)PK RAGDLLEDS(39.73)PK 9 2 640.79775 0.81218 577180 92339 0 0 440950 0 0 43898 852 633 322 322 2573;3213;5391 2926;2927;3645;6134;6136 52516 32107 Mix4_TiO2_Reinj_1_2 6368 52516 32107 Mix4_TiO2_Reinj_1_2 6368 P51946 P51946 P51946 >sp|P51946|CCNH_HUMAN Cyclin-H OS=Homo sapiens GN=CCNH PE=1 SV=1 1 151.14 0.120128 -8.01023 2.47448E-13 153.85 0 0 1 151.14 4.89027E-13 151.14 0 0 9.98538E-06 -49.9213 2.50612E-09 130.54 0.000232454 -36.3346 7.41762E-06 104.06 2 S DDDLVESL_____ NEK6 0.076 4.89027E-13 151.14 _SKHEEEEWpTDDDLVEpSL_ SKHEEEEWT(1)DDDLVES(1)L S(-68.98)KHEEEEWT(68.98)DDDLVES(151.14)L 16 2 1110.9165 0.036577 152540 0.27363 0 0 0 152540 0 0 0 853 633 307 307 3213;5391 3645;6134;6136 52517 32108 Mix4_TiO2_Reinj_1_2 6898 52516 32107 Mix4_TiO2_Reinj_1_2 6368 P51946 P51946 P51946 >sp|P51946|CCNH_HUMAN Cyclin-H OS=Homo sapiens GN=CCNH PE=1 SV=1 1 64.7649 0.120128 -8.01023 2.47448E-13 153.85 0 0 1 64.7649 4.89027E-13 151.14 0 0 0.0193945 -17.0381 2.50612E-09 130.54 0.000236345 -36.2625 7.41762E-06 104.06 2 S DYVSKKSKHEEEE CK1;CK2 0.081 4.89027E-13 151.14 _pSKHEEEEWpTDDDLVESL_ S(1)KHEEEEWT(1)DDDLVESL S(64.76)KHEEEEWT(64.76)DDDLVES(-64.76)L 1 2 1110.9165 -0.068095 32974 0.071347 0 0 0 32974 0 0 0 854 634 279 279 75 89 863 572 Mix4_InSol_TiO2_1 6081 871 586 Mix4_TiO2_Reinj_1_2 4914 P51948 P51948 P51948 >sp|P51948|MAT1_HUMAN CDK-activating kinase assembly factor MAT1 OS=Homo sapiens GN=MNAT1 PE=1 SV=1 1 97.3762 0.999999 63.4792 2.79296E-10 127.58 1 76.2118 6.21304E-11 135.18 1 97.3762 2.69813E-10 127.91 0.999999 66.7943 0.00995953 70.747 1 S NHVRAASPQDLAG CAMK2;CK2;Proline-directed 0.042 6.21304E-11 135.18 _AApSPQDLAGGYTSSLACHR_ AAS(1)PQDLAGGYTSSLACHR AAS(97.38)PQDLAGGY(-101.61)T(-97.38)S(-104.03)S(-117.25)LACHR 3 2 1021.4435 0.024863 4307900 642970 0 0 2215400 0 1206400 243200 855 635 296 296 4621 5244 43845 26877 Mix4_TiO2_1_4 5122 43845 26877 Mix4_TiO2_1_4 5122 P51955;P51955-2;P51955-3 P51955 P51955 >sp|P51955|NEK2_HUMAN Serine/threonine-protein kinase Nek2 OS=Homo sapiens GN=NEK2 PE=1 SV=1;>sp|P51955-2|NEK2_HUMAN Isoform B of Serine/threonine-protein kinase Nek2 OS=Homo sapiens GN=NEK2;>sp|P51955-3|NEK2_HUMAN Isoform 3 of Serine/threonine-protein kin 0.963046 17.237 0.963046 17.237 0.103362 50.067 0 0 1 S LGEPEKSQDSSPV GSK3 0.081 0.103362 50.067 _QLGEPEKpSQDSSPVLSELK_ QLGEPEKS(0.963)QDS(0.018)S(0.018)PVLS(0.001)ELK QLGEPEKS(17.24)QDS(-17.24)S(-17.24)PVLS(-32.32)ELK 8 3 717.67875 -0.2941 45999 45999 0 0 0 0 0 0 856 636 354 354 2973 3381 28306 17582 Mix4_TiO2_1_4 2331 28304 17580 Mix4_InSol_TiO2_1 2196 P51956;P51956-2 P51956 P51956 >sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo sapiens GN=NEK3 PE=1 SV=2;>sp|P51956-2|NEK3_HUMAN Isoform 2 of Serine/threonine-protein kinase Nek3 OS=Homo sapiens GN=NEK3 0.998496 28.2196 0.998496 28.2196 0.247765 28.22 0.877813 8.56377 0.0535706 45.923 0.991153 20.4934 0.00707911 63.473 0.872673 8.35931 0.0529366 46.124 1 S VHLRKASSPNLHR CAMK2;PKA 0.004788 0.00707911 63.473 _KApSSPNLHR_ KAS(0.998)S(0.002)PNLHR KAS(28.22)S(-28.22)PNLHR 3 2 545.26368 0.075507 1770300 15195 0 0 1520100 0 134860 100140 857 636 355 355 2973 3381 28307 17583 Mix4_TiO2_Reinj_1_3 1832 28304 17580 Mix4_InSol_TiO2_1 2196 P51956;P51956-2 P51956 P51956 >sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo sapiens GN=NEK3 PE=1 SV=2;>sp|P51956-2|NEK3_HUMAN Isoform 2 of Serine/threonine-protein kinase Nek3 OS=Homo sapiens GN=NEK3 0.790753 5.77383 0.00150447 -28.2196 0.247765 28.22 0.790753 5.77383 0.0535706 45.923 0.0088471 -20.4934 0.00707911 63.473 0.127327 -8.35931 0.0529366 46.124 1 S HLRKASSPNLHRR CHK1;PKD;Polo box;Proline-directed 0.00405 0.00707911 63.473 _KASpSPNLHR_ KAS(0.209)S(0.791)PNLHR KAS(-5.77)S(5.77)PNLHR 4 2 545.26368 -1.5294 87274 0 0 0 87274 0 0 0 858 637 340 340 496 562 4592 2779 Mix4_TiO2_1_3 4337 4595 2783 Mix4_TiO2_Reinj_1_3 5106 P51957;P51957-2 P51957 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 PE=1 SV=2;>sp|P51957-2|NEK4_HUMAN Isoform 2 of Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 0.999995 53.1591 0.999995 53.1591 2.55717E-05 135.4 0 0 0.999991 50.4134 1.21779E-07 156.52 0.999645 34.4925 0.00390258 88.91 0.999911 42.305 0.0704831 45.148 1 S ASGLLKSPASLKA NEK6;Proline-directed 0.05 1.21779E-07 156.52 _ASGLLKpSPASLK_ ASGLLKS(1)PASLK AS(-53.16)GLLKS(53.16)PAS(-75.76)LK 7 2 626.33905 0.32315 2858600 484450 0 0 1587400 0 442650 344040 859 637 563 563 982;4828 1104;5481 46102 28177 Mix4_TiO2_Reinj_1_3 7007 9371 5724 Mix4_TiO2_1_5 6551 P51957;P51957-2 P51957 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 PE=1 SV=2;>sp|P51957-2|NEK4_HUMAN Isoform 2 of Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 1 62.2309 1 122.76 0.00260214 122.76 0 0 1 62.2309 0.00312119 115.84 1 S LFAFQESPPRFLP CDK1;CDK2;Proline-directed 0.0057 0.00260214 122.76 _RDLFAFQEpSPPR_ RDLFAFQES(1)PPR RDLFAFQES(62.23)PPR 9 3 514.90821 -0.63302 1534000 410860 0 0 1123100 0 0 0 860 637 461 461 1152 1296 10819 6655 Mix4_TiO2_Reinj_1_3 4377 10820 6656 Mix4_TiO2_Reinj_1_5 4416 P51957 P51957 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 PE=1 SV=2 0.787936 5.70024 0 0 0.787936 5.70024 0.109704 38.068 1 S DQSLALSPKLECS CDK1;CK1;NEK6;Proline-directed 0.0057 0.109704 38.068 _DQSLALpSPK_ DQS(0.212)LALS(0.788)PK DQS(-5.7)LALS(5.7)PK 7 2 519.747 0.10158 303480 0 0 0 303480 0 0 0 861 637 484 484 3545 3998 33452 20631 Mix4_TiO2_1_3 2958 33452 20631 Mix4_TiO2_1_3 2958 P51957 P51957 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 PE=1 SV=2 0.976211 17.3391 0.976211 17.3391 0.0190321 62.529 0.208842 -3.11465 0.538083 16.993 0 0 0 0 1 S LLGSSDSPASASR CK1;Proline-directed 0.05 0.0190321 62.529 _LLGSSDpSPASASR_ LLGSS(0.018)DS(0.976)PAS(0.006)ASR LLGS(-43.46)S(-17.34)DS(17.34)PAS(-22.32)AS(-48.56)R 7 2 664.29811 -0.8073 33618 33618 0 0 0 0 0 0 862 637 489 489 3545 3998 33453 20632 Mix4_TiO2_Reinj_1_5 3815 33452 20631 Mix4_TiO2_1_3 2958 P51957 P51957 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 PE=1 SV=2 0.427841 1.06667 1.36146E-05 -48.5554 0.0190321 62.529 0.427841 1.06667 0.538083 16.993 0 0 0 0 1 S DSPASASRVAGIT 0.0190321 62.529 _LLGSSDSPASApSR_ LLGS(0.009)S(0.02)DS(0.209)PAS(0.335)AS(0.428)R LLGS(-16.99)S(-13.28)DS(-3.11)PAS(-1.07)AS(1.07)R 12 2 664.29811 0.58567 0 0 0 0 0 0 0 0 863 637 661 661 4954 5632 47685 29134 Mix4_TiO2_1_5 2667 47686 29135 Mix4_TiO2_Reinj_1_3 3170 P51957;P51957-2 P51957 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 PE=1 SV=2;>sp|P51957-2|NEK4_HUMAN Isoform 2 of Serine/threonine-protein kinase Nek4 OS=Homo sapiens GN=NEK4 0.990568 20.2153 0.990568 20.2153 0.0185762 59.844 0.884995 8.8625 0.00264473 93.424 0.987362 18.9426 0.00366006 89.78 0.87297 8.40069 0.0113256 70.837 1 S LPARRLSSDCSVT CAMK2;GSK3;PKA 0.004788 0.00264473 93.424 _RLpSSDCSVTQER_ RLS(0.991)S(0.009)DCSVTQER RLS(20.22)S(-20.22)DCS(-53.62)VT(-59.84)QER 3 2 759.32434 -0.38118 1165500 91613 0 0 645280 0 243630 184990 864 638 356 356 5713 6510 56111 34322 Mix4_TiO2_1_4 3320 56111 34322 Mix4_TiO2_1_4 3320 P51991;P51991-2 P51991 P51991 >sp|P51991|ROA3_HUMAN Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens GN=HNRNPA3 PE=1 SV=2;>sp|P51991-2|ROA3_HUMAN Isoform 2 of Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens GN=HNRNPA3 0.553714 1.41483 0.553714 1.41483 5.37287E-17 148.78 0 0 0 0 0.356052 0 0.113526 51.774 1 S SFGGRSSGSPYGG PKA 0.042 5.37287E-17 148.78 _SpSGSPYGGGYGSGGGSGGYGSR_ S(0.4)S(0.554)GS(0.047)PYGGGYGSGGGSGGYGSR S(-1.41)S(1.41)GS(-10.76)PY(-49.74)GGGY(-79.77)GS(-88.02)GGGS(-129.4)GGY(-140.34)GS(-133.18)R 2 2 995.88179 0.95746 68766 68766 0 0 0 0 0 0 865 638 358 358 5713 6510 56110 34321 Mix4_InSol_Tio2_Reinj_1 4057 56111 34322 Mix4_TiO2_1_4 3320 P51991;P51991-2 P51991 P51991 >sp|P51991|ROA3_HUMAN Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens GN=HNRNPA3 PE=1 SV=2;>sp|P51991-2|ROA3_HUMAN Isoform 2 of Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens GN=HNRNPA3 0.356052 0 0.0465175 -10.7567 5.37287E-17 148.78 0 0 0 0 0.356052 0 0.113526 51.774 1 S GGRSSGSPYGGGY CK1;Proline-directed 0.05 5.37287E-17 148.78 _SpSGSPYGGGYGSGGGSGGYGSR_ S(0.288)S(0.356)GS(0.356)PYGGGYGSGGGSGGYGSR S(-0.93)S(0)GS(0)PY(-31.05)GGGY(-51.77)GS(-48.95)GGGS(-51.77)GGY(-51.77)GS(-51.77)R 4 2 995.88179 0.1648 0 0 0 0 0 0 0 0 866 640 62 62 4380 4981 41557 25544 Mix4_TiO2_1_4 4856 41557 25544 Mix4_TiO2_1_4 4856 P52292 P52292 P52292 >sp|P52292|IMA2_HUMAN Importin subunit alpha-2 OS=Homo sapiens GN=KPNA2 PE=1 SV=1 0.997196 25.5103 0.997196 25.5103 1.60416E-33 215.07 0 0 0.857658 7.79982 1.96114E-20 186.22 0.860012 7.88414 3.16664E-06 112.12 0.477266 -0.395202 0.0210302 63.229 1 S FPDDATSPLQENR Proline-directed 0.05 1.60416E-33 215.07 _NVSSFPDDATpSPLQENR_ NVSSFPDDAT(0.003)S(0.997)PLQENR NVS(-156.3)S(-149.47)FPDDAT(-25.51)S(25.51)PLQENR 11 2 978.92038 0.68843 699730 3.45 180930 0 0 438960 0 79844 0 867 641 26 26 1386 1558 12950 7982 Mix4_InSol_Tio2_Reinj_1 4845 12949 7981 Mix4_InSol_TiO2_1 4900 P52564 P52564 P52564 >sp|P52564|MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens GN=MAP2K6 PE=1 SV=1 0.310719 0 0.232391 -3.09899 0.214582 40.007 0 0 0.0155693 -17.3975 0.0140827 66.639 0.261492 -1.46915 0.00756307 73.135 0.310719 0 0.396345 35.287 1 S FEQPQTSSTPPRD 0.00756307 73.135 _EAFEQPQTpSSTPPRDLDSK_ EAFEQPQT(0.068)S(0.311)S(0.311)T(0.311)PPRDLDSK EAFEQPQT(-6.61)S(0)S(0)T(0)PPRDLDS(-35.29)K 9 3 738.33012 0.037719 0 0 0 0 0 0 0 0 868 641 27 27 1386 1558 12949 7981 Mix4_InSol_TiO2_1 4900 12949 7981 Mix4_InSol_TiO2_1 4900 P52564 P52564 P52564 >sp|P52564|MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens GN=MAP2K6 PE=1 SV=1 0.366752 0 0.232391 -3.09899 0.214582 40.007 0 0 0.111416 -8.85072 0.0140827 66.639 0.366752 0 0.00756307 73.135 0.310719 0 0.396345 35.287 1 S EQPQTSSTPPRDL 0.00756307 73.135 _EAFEQPQTSpSTPPRDLDSK_ EAFEQPQT(0.005)S(0.261)S(0.367)T(0.367)PPRDLDSK EAFEQPQT(-18.9)S(-1.47)S(0)T(0)PPRDLDS(-31.11)K 10 3 738.33012 -0.51477 0 0 0 0 0 0 0 0 869 642 179 179 2503 2843 23560 14657 Mix4_InSol_TiO2_1 3007 23564 14662 Mix4_TiO2_Reinj_1_4 2733 P52594;P52594-3;P52594-2 P52594 P52594 >sp|P52594|AGFG1_HUMAN Arf-GAP domain and FG repeats-containing protein 1 OS=Homo sapiens GN=AGFG1 PE=1 SV=2;>sp|P52594-3|AGFG1_HUMAN Isoform 3 of Arf-GAP domain and FG repeats-containing protein 1 OS=Homo sapiens GN=AGFG1;>sp|P52594-2|AGFG1_HUMAN Isoform 0.692059 5.22774 0.00226128 -26.4466 0.00676755 70.372 0 0 0.108798 -9.06601 0.00385082 77.547 0.692059 5.22774 0.277523 23.695 0.00535206 -22.6895 0.0748116 41.277 1 S LNKGTPSQSPVVG 0.00385082 77.547 _GTPpSQSPVVGR_ GT(0.1)PS(0.692)QS(0.208)PVVGR GT(-8.39)PS(5.23)QS(-5.23)PVVGR 4 2 582.77408 -0.23588 84844 0 0 0 0 0 84844 0 870 642 181 181 2503 2843 23564 14662 Mix4_TiO2_Reinj_1_4 2733 23564 14662 Mix4_TiO2_Reinj_1_4 2733 P52594;P52594-3;P52594-2 P52594 P52594 >sp|P52594|AGFG1_HUMAN Arf-GAP domain and FG repeats-containing protein 1 OS=Homo sapiens GN=AGFG1 PE=1 SV=2;>sp|P52594-3|AGFG1_HUMAN Isoform 3 of Arf-GAP domain and FG repeats-containing protein 1 OS=Homo sapiens GN=AGFG1;>sp|P52594-2|AGFG1_HUMAN Isoform 0.999885 39.4182 0.997739 26.4466 0.00676755 70.372 0 0 0.999885 39.4182 0.00385082 77.547 0.207667 -5.22774 0.277523 23.695 0.994203 22.6895 0.0748116 41.277 1 S KGTPSQSPVVGRS CK1;Proline-directed 0.05 0.00385082 77.547 _GTPSQpSPVVGR_ GTPSQS(1)PVVGR GT(-64.94)PS(-39.42)QS(39.42)PVVGR 6 2 582.77408 0.56719 426790 68295 0 0 255680 0 0 102810 871 645 768 768 534 607 5000 3019 Mix4_InSol_TiO2_1 4314 5004 3023 Mix4_TiO2_Reinj_1_3 3910 P52735-3 P52735-3 P52735-3 >sp|P52735-3|VAV2_HUMAN Isoform 3 of Guanine nucleotide exchange factor VAV2 OS=Homo sapiens GN=VAV2 0.543393 1.34765 0.396291 0 0.171803 32.744 0.48987 0 0.0331166 53.642 0.543393 1.34765 0.0757083 41.011 0.0713123 -10.2478 0.544229 10.248 1 S RSASRASSRSPVF CK1;PKA 0.042 0.0331166 53.642 _ApSSRSPVFTPR_ AS(0.543)S(0.398)RS(0.057)PVFT(0.001)PR AS(1.35)S(-1.35)RS(-9.79)PVFT(-26.73)PR 2 2 642.80845 -0.050715 82779 0 0 0 0 0 82779 0 872 645 769 769 534 607 5001 3020 Mix4_InSol_TiO2_2 3215 5004 3023 Mix4_TiO2_Reinj_1_3 3910 P52735-3 P52735-3 P52735-3 >sp|P52735-3|VAV2_HUMAN Isoform 3 of Guanine nucleotide exchange factor VAV2 OS=Homo sapiens GN=VAV2 0.889393 9.69371 0.396291 0 0.171803 32.744 0.48987 0 0.0331166 53.642 0.889393 9.69371 0.0757083 41.011 0.755003 8.67764 0.544229 10.248 1 S SASRASSRSPVFT CAMK2;CK1 0.042 0.0331166 53.642 _ASpSRSPVFTPR_ AS(0.015)S(0.889)RS(0.095)PVFTPR AS(-17.7)S(9.69)RS(-9.69)PVFT(-41.01)PR 3 2 642.80845 0.25903 70292 0 0 0 0 0 21879 48413 873 646 624 624 2324 2629 21544 13192 Mix4_TiO2_Reinj_1_5 6269 21544 13192 Mix4_TiO2_Reinj_1_5 6269 P52756 P52756 P52756 >sp|P52756|RBM5_HUMAN RNA-binding protein 5 OS=Homo sapiens GN=RBM5 PE=1 SV=2 1 112.404 0 0 1 112.404 3.30109E-39 227.87 1 S AAYSGDSDNEEEL CK1;CK2 0.081 3.30109E-39 227.87 _GLVAAYSGDpSDNEEELVER_ GLVAAYSGDS(1)DNEEELVER GLVAAY(-170.64)S(-112.4)GDS(112.4)DNEEELVER 10 2 1066.9546 0.028231 402600 0 0 0 402600 0 0 0 874 648 260 260 3061 3481 29172 18228 Mix4_TiO2_Reinj_1_4 5683 29172 18228 Mix4_TiO2_Reinj_1_4 5683 P52799 P52799 P52799 >sp|P52799|EFNB2_HUMAN Ephrin-B2 OS=Homo sapiens GN=EFNB2 PE=1 SV=1 0.99907 30.6607 0.99907 30.6607 0.000678902 87.304 1 S RRHRKHSPQHTTT CAMK2;PKA;PKA/AKT;Proline-directed 0.001764 0.000678902 87.304 _KHpSPQHTTTLSLSTLATPK_ KHS(0.999)PQHT(0.001)TTLSLSTLATPK KHS(30.66)PQHT(-30.66)T(-44.34)T(-64.14)LS(-45.07)LS(-54.37)T(-63.63)LAT(-71.28)PK 3 3 710.03145 -1.5273 320710 0 0 0 320710 0 0 0 875 649 1023 1023 133 154 1332 833 Mix4_TiO2_Reinj_1_5 3394 1331 832 Mix4_TiO2_Reinj_1_5 2957 P52948;P52948-5;P52948-2;P52948-6 P52948 P52948 >sp|P52948|NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98 PE=1 SV=4;>sp|P52948-5|NUP98_HUMAN Isoform ADIR2 of Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98;>sp|P52948-2|NUP98_HUMAN Isoform Nup98-Nup96 prec 0.94078 12.0795 0.400767 -1.67732 0.381193 17.91 0.94078 12.0795 0.00297179 80.386 1 S PSKADTSQEICSP 0.00297179 80.386 _ADTpSQEICSPR_ ADT(0.058)S(0.941)QEICS(0.001)PR ADT(-12.08)S(12.08)QEICS(-30.01)PR 4 2 672.2685 0.54752 57938 0 0 0 57938 0 0 0 876 649 1028 1028 133 154 1331 832 Mix4_TiO2_Reinj_1_5 2957 1331 832 Mix4_TiO2_Reinj_1_5 2957 P52948;P52948-5;P52948-2;P52948-6 P52948 P52948 >sp|P52948|NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98 PE=1 SV=4;>sp|P52948-5|NUP98_HUMAN Isoform ADIR2 of Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98;>sp|P52948-2|NUP98_HUMAN Isoform Nup98-Nup96 prec 1 80.3862 0.00954207 -17.9098 0.381193 17.91 1 80.3862 0.00297179 80.386 1 S TSQEICSPRLPIS CDK1;Proline-directed 0.0057 0.00297179 80.386 _ADTSQEICpSPR_ ADTSQEICS(1)PR ADT(-80.39)S(-80.39)QEICS(80.39)PR 9 2 672.2685 0.29661 89830 0 0 0 89830 0 0 0 877 649 888 888 6733 7706 68258 41851 Mix4_TiO2_Reinj_1_5 3909 68258 41851 Mix4_TiO2_Reinj_1_5 3909 P52948;P52948-5;P52948-2;P52948-6;P52948-3;P52948-4 P52948 P52948 >sp|P52948|NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98 PE=1 SV=4;>sp|P52948-5|NUP98_HUMAN Isoform ADIR2 of Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98;>sp|P52948-2|NUP98_HUMAN Isoform Nup98-Nup96 prec 1 94.4845 1 66.4481 2.94019E-06 113.99 0.999048 33.2191 0.371031 33.219 1 94.4845 2.20598E-12 145.37 0 0 0 0 1 S KYGLQDSDEEEEE CK2;NEK6 0.076 2.20598E-12 145.37 _YGLQDpSDEEEEEHPSK_ YGLQDS(1)DEEEEEHPSK Y(-94.48)GLQDS(94.48)DEEEEEHPS(-133.58)K 6 3 657.92124 0.07537 5067600 1364200 17642 0 3685700 0 0 0 878 650 156 156 1997 2259 18145 10824 Mix4_TiO2_Reinj_1_6 2495 18145 10824 Mix4_TiO2_Reinj_1_6 2495 P53007 P53007 P53007 >sp|P53007|TXTP_HUMAN Tricarboxylate transport protein, mitochondrial OS=Homo sapiens GN=SLC25A1 PE=1 SV=2 0.700598 3.69215 0 0 0.700598 3.69215 0.0940616 39.398 1 S FIHDQTSPNPKYR Proline-directed 0.05 0.0940616 39.398 _FIHDQTpSPNPK_ FIHDQT(0.299)S(0.701)PNPK FIHDQT(-3.69)S(3.69)PNPK 7 2 682.30574 -0.18998 29973 0 0 0 29973 0 0 0 879 652 481 481 303 345;346 2820 1733 Mix4_InSol_TiO2_1 3585 2822 1736 Mix4_TiO2_Reinj_1_5 3297 P53396 P53396 P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 0.999783 36.624 0.984685 18.0818 0.00312806 81.269 0.999496 32.9718 0.00164574 90.22 0.999783 36.624 0.191354 36.624 0 0 1 S PQDSVPSPRSLQG CDK1;CK1;ERK/MAPK;Proline-directed 0.0034 0.00164574 90.22 _AKPAM(ox)PQDSVPpSPR_ AKPAMPQDSVPS(1)PR AKPAMPQDS(-36.62)VPS(36.62)PR 12 2 788.8631 0.74282 250960 57780 0 0 152950 0 40235 0 880 652 455 455 5901;5902;5903 6730;6731;6732 58171 35332 Mix4_TiO2_Reinj_1_3 2805 58191 35338 Mix4_InSol_TiO2_1 4153 P53396 P53396 P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 0.986332 19.0035 0.986236 18.5782 0.00954965 73.068 0 0 0.986332 19.0035 0.00954967 73.068 0.817939 7.62408 7.31489E-06 104.23 0.49118 4.61798 0.0561844 55.654 1 S APSRTASFSESRA CAMK2;CK1;CK2;GSK3;PKA/AKT 0.00111111 7.31489E-06 104.23 _TApSFSESR_ T(0.001)AS(0.986)FS(0.012)ESR T(-29.84)AS(19)FS(-19)ES(-36.16)R 3 2 482.69222 0.027778 8545500 1052900 0 0 3764200 0 3728400 0 881 652 457 457 5901;5902;5903 6730;6731;6732 58197 35344 Mix4_TiO2_1_5 3264 58191 35338 Mix4_InSol_TiO2_1 4153 P53396 P53396 P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 0.467028 0 0.467028 0 0.00954965 73.068 0 0 0.155743 -7.3405 0.00954967 73.068 0.0365598 -13.4972 7.31489E-06 104.23 0.349845 0 0.0561844 55.654 1 S SRTASFSESRADE CK1 0.143 7.31489E-06 104.23 _TApSFSESRADEVAPAKK_ T(0.064)AS(0.467)FS(0.467)ES(0.002)RADEVAPAKK T(-8.62)AS(0)FS(0)ES(-24.14)RADEVAPAKK 5 2 937.43821 -0.1549 0 0 0 0 0 0 0 0 882 652 459 459 5901;5902;5903 6730;6731;6732 58194 35341 Mix4_InSol_Tio2_Reinj_1 4133 58191 35338 Mix4_InSol_TiO2_1 4153 P53396 P53396 P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 0.261416 0 0.167325 -4.73688 0.00954965 73.068 0 0 0.00200781 -24.3875 0.00954967 73.068 0.00414583 -22.9511 7.31489E-06 104.23 0.261416 0 0.0561844 55.654 1 S TASFSESRADEVA CK1;CK2 0.117 7.31489E-06 104.23 _TApSFSESRADEVAPAKK_ T(0.216)AS(0.261)FS(0.261)ES(0.261)RADEVAPAKK T(-0.83)AS(0)FS(0)ES(0)RADEVAPAKK 7 2 937.43821 0.33373 0 0 0 0 0 0 0 0 883 655 402 402 707;708 811;813 6841 4065 Mix4_TiO2_Reinj_1_5 2093 6841 4065 Mix4_TiO2_Reinj_1_5 2093 P53621-2;P53621 P53621-2 P53621-2 >sp|P53621-2|COPA_HUMAN Isoform 2 of Coatomer subunit alpha OS=Homo sapiens GN=COPA;>sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapiens GN=COPA PE=1 SV=2 1 62.035 1 36.0224 0.171006 36.022 1 62.035 0.0218778 62.035 1 S IPKDADSQNPDAP 0.0218778 62.035 _DADpSQNPDAPEGKR_ DADS(1)QNPDAPEGKR DADS(62.03)QNPDAPEGKR 4 2 790.32285 -0.55611 129690 0.017066 15607 0 0 114080 0 0 0 884 655 904 904 2371 2684 21943 13643 Mix4_TiO2_Reinj_2_2 3612 21944 13644 Mix4_TiO2_Reinj_1_6 7646 P53621-2;P53621 P53621-2 P53621-2 >sp|P53621-2|COPA_HUMAN Isoform 2 of Coatomer subunit alpha OS=Homo sapiens GN=COPA;>sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapiens GN=COPA PE=1 SV=2 0.999257 31.2871 0 0 0 0 0.987166 18.8604 0.0586406 77.502 0.999257 31.2871 0.106726 75.601 1 S PPELDISPGAAGG NEK6;Proline-directed 0.05 0.0586406 77.502 _GQEEGGGWDVEEDLELPPELDIpSPGAAGGAEDGFFVPPTK_ GQEEGGGWDVEEDLELPPELDIS(0.999)PGAAGGAEDGFFVPPT(0.001)K GQEEGGGWDVEEDLELPPELDIS(31.29)PGAAGGAEDGFFVPPT(-31.29)K 23 3 1397.958 1.1612 2288000 0.19346 0 0 0 1585700 702320 0 0 885 655 173 173 4163 4739 39679 24488 Mix4_TiO2_Reinj_1_5 5628 39674 24479 Mix4_TiO2_1_5 4728 P53621-2;P53621 P53621-2 P53621-2 >sp|P53621-2|COPA_HUMAN Isoform 2 of Coatomer subunit alpha OS=Homo sapiens GN=COPA;>sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sapiens GN=COPA PE=1 SV=2 1 97.4595 1 121.622 1.01987E-05 142.7 1 106.82 0.000722257 106.82 1 97.4595 9.51087E-05 123.49 0 0 1 77.7682 0.00370799 89.608 1 85.3297 0.000645679 108.27 1 S LRKKNLSPGAVES Proline-directed 0.05 1.01987E-05 142.7 _NLpSPGAVESDVR_ NLS(1)PGAVESDVR NLS(97.46)PGAVES(-97.46)DVR 3 2 662.30066 0.02183 3754600 18.687 434860 28853 0 2449800 0 477800 363230 886 656 296 296 5144;5145 5855;5856;5857;5858 49886 30510 Mix4_InSol_TiO2_1 4192 49857 30502 Mix4_TiO2_Reinj_1_3 4138 P53667;P53667-2 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 0.706416 4.0593 0.495332 0 4.6705E-17 155.52 0 0 0.117997 -8.08404 1.52341E-26 181.92 0.706416 4.0593 1.3675E-21 158.02 0.471618 0 3.42432E-07 114.69 2 S QKPVLRSCSIDRS 1.3675E-21 158.02 _pSCSIDRSPGAGSLGpSPASQRK_ S(0.706)CS(0.273)IDRS(0.021)PGAGS(0.112)LGS(0.885)PAS(0.004)QRK S(4.06)CS(-4.06)IDRS(-15.44)PGAGS(-8.76)LGS(8.76)PAS(-27.92)QRK 1 3 759.99428 -0.74415 1624400 0 0 0 0 0 1624400 0 887 656 298 298 5144;5145 5855;5856;5857;5858 49833 30488 Mix4_TiO2_1_3 3515 49835 30490 Mix4_TiO2_Reinj_1_3 3997 P53667;P53667-2 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 0.92172 10.7101 0.92172 10.7101 4.6705E-17 155.52 0 0 0.901464 9.61399 1.52341E-26 181.92 0.876719 8.60634 1.3675E-21 158.02 0.862743 8.00699 1.18364E-06 106.26 1 S PVLRSCSIDRSPG CAMK2;CHK1;GSK3;PKD 0.020748 1.52341E-26 181.92 _SCpSIDRSPGAGSLGSPASQR_ S(0.078)CS(0.922)IDRSPGAGSLGSPASQR S(-10.71)CS(10.71)IDRS(-50.02)PGAGS(-59.01)LGS(-111.87)PAS(-155.52)QR 3 2 1035.4571 -0.27558 5152400 989260 0 0 2904700 0 1133700 124760 888 656 302 302 5144;5145;5557;5558 5855;5856;5857;5858;6332;6333 49835 30490 Mix4_TiO2_Reinj_1_3 3997 54384 33306 Mix4_TiO2_Reinj_1_4 3330 P53667;P53667-2 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 0.988298 21.5587 0.89768 9.52252 1.50914E-15 176.97 1.62848E-06 -57.8071 0.0339995 57.807 0.988298 21.5587 9.69661E-16 183.49 0 0 0.205641 -5.20022 2.29934E-16 150.99 0.849735 10.3992 7.29353E-07 129.82 1 S SCSIDRSPGAGSL CK1;Proline-directed 0.05 9.69661E-16 183.49 _SCSIDRpSPGAGSLGSPASQR_ S(0.005)CS(0.007)IDRS(0.988)PGAGSLGSPASQR S(-23.2)CS(-21.56)IDRS(21.56)PGAGS(-41.65)LGS(-95.58)PAS(-157.58)QR 7 2 1035.4571 0.79789 2187100 277840 0 0 1073200 0 0 836000 889 656 307 307 5144;5145;5557;5558 5855;5856;5857;5858;6332;6333 49887 30511 Mix4_InSol_TiO2_1 4167 49857 30502 Mix4_TiO2_Reinj_1_3 4138 P53667;P53667-2 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 0.794558 10.0657 0.0163346 -17.5716 1.50914E-15 176.97 0.000340128 -34.6085 0.0339995 57.807 0.0151837 -17.4355 9.69661E-16 183.49 0 0 0.794558 10.0657 1.3675E-21 158.02 0.352693 -2.31608 1.18364E-06 106.26 2 S RSPGAGSLGSPAS 1.3675E-21 158.02 _pSCSIDRSPGAGpSLGSPASQRK_ S(0.494)CS(0.494)IDRS(0.087)PGAGS(0.795)LGS(0.058)PAS(0.073)QRK S(0)CS(0)IDRS(-10.07)PGAGS(10.07)LGS(-11.67)PAS(-10.56)QRK 12 2 1139.4878 0.30885 126960 0 0 0 0 0 126960 0 890 656 310 310 5144;5145;5557;5558 5855;5856;5857;5858;6332;6333 54377 33292 Mix4_TiO2_1_3 2695 54384 33306 Mix4_TiO2_Reinj_1_4 3330 P53667;P53667-2 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 1 66.428 1 66.428 1.50914E-15 176.97 0.982856 17.6713 0.0339995 57.807 0.999998 56.8644 9.69661E-16 183.49 0 0 0.999967 44.8403 2.29934E-16 150.99 0.999955 43.4973 7.29353E-07 129.82 1 S GAGSLGSPASQRK CK1;Proline-directed 0.05 9.69661E-16 183.49 _SPGAGSLGpSPASQR_ SPGAGSLGS(1)PASQR S(-173.69)PGAGS(-114.32)LGS(66.43)PAS(-66.43)QR 9 2 676.30373 -0.86274 35154000 6788700 53374 0 21095000 0 4089600 3127300 891 656 313 313 5144;5145;5557;5558 5855;5856;5857;5858;6332;6333 54407 33315 Mix4_TiO2_1_3 2344 54384 33306 Mix4_TiO2_Reinj_1_4 3330 P53667;P53667-2 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 0.575368 1.38907 0.575368 1.38907 1.50914E-15 176.97 0.0168018 -17.6713 0.0339995 57.807 0.141774 -7.73329 9.69661E-16 183.49 0 0 0.198905 -3.06964 2.29934E-16 150.99 0.0904698 -5.02098 7.29353E-07 129.82 1 S SLGSPASQRKDLG CK1 0.081 9.69661E-16 183.49 _SPGAGSLGSPApSQRK_ SPGAGS(0.007)LGS(0.418)PAS(0.575)QRK S(-36)PGAGS(-19.39)LGS(-1.39)PAS(1.39)QRK 12 3 493.90323 1.2843 57547 57547 0 0 0 0 0 0 892 656 210 210 6562 7507;7508 66431 40775 Mix4_InSol_Tio2_Reinj_1 4962 66430 40774 Mix4_InSol_TiO2_1 5039 P53667;P53667-2;P53667-3 P53667 P53667 >sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3;>sp|P53667-2|LIMK1_HUMAN Isoform 2 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1;>sp|P53667-3|LIMK1_HUMAN Isoform 3 of LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 1 108.573 1 74.5821 0.00865539 74.582 1 94.0133 0.00101744 94.013 1 156.522 1.125E-10 156.52 1 108.573 0.000111701 108.57 1 S VDPGCMSPDVKNS Proline-directed 0.05 1.125E-10 156.52 _VQGVDPGCMpSPDVK_ VQGVDPGCMS(1)PDVK VQGVDPGCMS(108.57)PDVK 10 2 784.82787 -0.20086 560080 51314 0 0 148970 0 195770 164040 893 657 287 287 5524;5525 6289;6290;6291 53927 32979 Mix4_InSol_TiO2_1 6521 53927 32979 Mix4_InSol_TiO2_1 6521 P53671;P53671-2 P53671 P53671 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 PE=1 SV=1;>sp|P53671-2|LIMK2_HUMAN Isoform LIMK2b of LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 0.945597 13.059 0.977205 16.3318 0.0118477 71.534 0.996551 24.6151 0.00885828 74.366 0.945597 13.059 0.00773359 71.116 0.923716 11.9848 0.17443 44.551 1 S RRSLRRSNSISKS CK1;GSK3;NEK6;NIMA;PKA 0.001741464 0.00773359 71.116 _pSNSISKSPGPSSPKEPLLFSR_ S(0.946)NS(0.047)IS(0.008)KSPGPSSPKEPLLFSR S(13.06)NS(-13.06)IS(-20.92)KS(-52.72)PGPS(-68.77)S(-71.12)PKEPLLFS(-71.12)R 1 3 765.71754 -0.25261 790630 0 0 0 0 0 339330 451300 894 657 293 293 5524;5525;5562 6289;6290;6291;6337 53923 32977 Mix4_TiO2_Reinj_1_3 2262 53923 32977 Mix4_TiO2_Reinj_1_3 2262 P53671;P53671-2 P53671 P53671 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 PE=1 SV=1;>sp|P53671-2|LIMK2_HUMAN Isoform LIMK2b of LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 0.998478 30.3437 0.997869 27.4285 0.0118477 71.534 0 0 0.998478 30.3437 0.00885828 74.366 5.04933E-06 -52.7247 0.00773359 71.116 0.000495585 -32.7042 0.17443 44.551 2 S SNSISKSPGPSSP CK1;GSK3;Proline-directed 0.05 0.00885828 74.366 _pSNSISKpSPGPSSPK_ S(0.997)NS(0.003)IS(0.001)KS(0.998)PGPS(0.001)SPK S(24.62)NS(-24.62)IS(-30.34)KS(30.34)PGPS(-32.77)S(-41.62)PK 7 2 766.82331 0.10393 335450 62763 0 0 272690 0 0 0 895 657 297 297 5524;5525;5562 6289;6290;6291;6337 54457 33338 Mix4_TiO2_Reinj_1_4 6322 54457 33338 Mix4_TiO2_Reinj_1_4 6322 P53671;P53671-2 P53671 P53671 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 PE=1 SV=1;>sp|P53671-2|LIMK2_HUMAN Isoform LIMK2b of LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 0.902943 9.68632 0.499652 0 0.00228229 83.99 0 0 0.902943 9.68632 1.93125E-05 114.25 1.25632E-07 -68.7661 0.00773359 71.116 5.19692E-05 -42.4979 0.17443 44.551 1 S SKSPGPSSPKEPL CK1 0.143 1.93125E-05 114.25 _SPGPpSSPKEPLLFSR_ SPGPS(0.903)S(0.097)PKEPLLFSR S(-69.97)PGPS(9.69)S(-9.69)PKEPLLFS(-114.25)R 5 3 560.27819 -0.23422 401560 0 0 0 401560 0 0 0 896 657 298 298 5524;5525;5562 6289;6290;6291;6337 53932 32981 Mix4_TiO2_Reinj_1_3 6597 53932 32981 Mix4_TiO2_Reinj_1_3 6597 P53671;P53671-2 P53671 P53671 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 PE=1 SV=1;>sp|P53671-2|LIMK2_HUMAN Isoform LIMK2b of LIM domain kinase 2 OS=Homo sapiens GN=LIMK2 0.952544 12.9591 0.499652 0 0.00228229 83.99 0 0 0.952544 12.9591 0.101187 51.858 7.31319E-08 -71.116 0.00773359 71.116 3.23907E-05 -44.5512 0.17443 44.551 3 S KSPGPSSPKEPLL CDK1;CK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.101187 51.858 _pSNSISKpSPGPSpSPKEPLLFSR_ S(0.941)NS(0.059)IS(0.009)KS(0.964)PGPS(0.075)S(0.953)PKEPLLFSR S(12.1)NS(-12.1)IS(-20.38)KS(15.29)PGPS(-12.96)S(12.96)PKEPLLFS(-51.86)R 12 3 819.02842 -0.038094 321800 0 0 0 321800 0 0 0 897 661 102 102 1971 2231 18012 10771 Mix4_TiO2_Reinj_1_2 5787 18012 10771 Mix4_TiO2_Reinj_1_2 5787 P54105 P54105 P54105 >sp|P54105|ICLN_HUMAN Methylosome subunit pICln OS=Homo sapiens GN=CLNS1A PE=1 SV=1 1 74.1121 0 0 1 74.1121 1.30289E-18 151.48 0 0 0 0 1 S DEEEEDSDDDVEP CK2 0.117 1.30289E-18 151.48 _FEEESKEPVADEEEEDpSDDDVEPITEFR_ FEEESKEPVADEEEEDS(1)DDDVEPITEFR FEEES(-86.36)KEPVADEEEEDS(74.11)DDDVEPIT(-74.11)EFR 17 3 1132.1225 0.011992 272960 0 0 0 272960 0 0 0 898 664 377 377 3886 4412;4413 36850 22703 Mix4_TiO2_2_4 3724 36849 22702 Mix4_TiO2_1_4 3734 P54646 P54646 P54646 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2 1 21.2552 1 63.8857 0.0109417 63.886 1 21.2552 0.307533 21.255 0 0 0 0 1 S PPLIADSPKARCP CDK1;Proline-directed 0.0057 0.0109417 63.886 _M(ox)PPLIADpSPK_ MPPLIADS(1)PK MPPLIADS(21.26)PK 8 2 582.77216 0.14251 38777 17494 21283 0 0 0 0 0 899 664 500 500 5703 6497 55921 34230 Mix4_TiO2_Reinj_1_4 7318 55920 34229 Mix4_TiO2_Reinj_1_3 7377 P54646 P54646 P54646 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2 0.427077 6.97623 0.113885 0 0.0287076 71.628 0.427077 6.97623 0.000365423 81.326 1 S GLHRPRSSFDSTT CAMK2;CHK1;CHK1/2;CK2;GSK3;PKD 0.003192 0.000365423 81.326 _pSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPR_ S(0.427)S(0.086)FDS(0.086)T(0.086)T(0.086)AES(0.086)HS(0.086)LS(0.018)GS(0.014)LT(0.023)GS(0.003)LT(0.001)GSTLSSVSPR S(6.98)S(-6.98)FDS(-6.98)T(-6.98)T(-6.98)AES(-6.98)HS(-6.98)LS(-13.66)GS(-14.99)LT(-12.63)GS(-21.49)LT(-29.06)GS(-40.1)T(-45.05)LS(-53.59)S(-55.74)VS(-55.74)PR 1 3 1075.1595 0.50698 0 0 0 0 0 0 0 0 900 664 501 501 5703 6497 55920 34229 Mix4_TiO2_Reinj_1_3 7377 55920 34229 Mix4_TiO2_Reinj_1_3 7377 P54646 P54646 P54646 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2 0.37296 0.300384 0.113885 0 0.0287076 71.628 0.37296 0.300384 0.000365423 81.326 1 S LHRPRSSFDSTTA AURORA;PKA 0.038874 0.000365423 81.326 _SpSFDSTTAESHSLSGSLTGSLTGSTLSSVSPR_ S(0.348)S(0.373)FDS(0.085)T(0.085)T(0.085)AES(0.009)HS(0.011)LS(0.002)GS(0.002)LTGSLTGSTLSSVSPR S(-0.3)S(0.3)FDS(-6.43)T(-6.43)T(-6.43)AES(-16.08)HS(-15.46)LS(-22.29)GS(-22.29)LT(-34.7)GS(-46.2)LT(-61.35)GS(-73.9)T(-77.34)LS(-81.33)S(-81.33)VS(-81.33)PR 2 3 1075.1595 0.63212 0 0 0 0 0 0 0 0 901 664 504 504 5703 6497 55919 34228 Mix4_TiO2_1_3 6641 55920 34229 Mix4_TiO2_Reinj_1_3 7377 P54646 P54646 P54646 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2 0.113885 0 0.113885 0 0.0287076 71.628 0.0856808 -6.97623 0.000365423 81.326 1 S PRSSFDSTTAESH CK1 0.081 0.000365423 81.326 _pSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPR_ S(0.114)S(0.114)FDS(0.114)T(0.114)T(0.098)AES(0.106)HS(0.106)LS(0.106)GS(0.106)LT(0.021)GS(0.001)LTGSTLSSVSPR S(0)S(0)FDS(0)T(0)T(-0.64)AES(-0.31)HS(-0.31)LS(-0.31)GS(-0.31)LT(-7.32)GS(-22.98)LT(-44.18)GS(-56.05)T(-61.26)LS(-69.53)S(-71.63)VS(-71.63)PR 5 3 1075.1595 0.098225 0 0 0 0 0 0 0 0 902 664;843 176;202 202 6210 7094 61562 37310 Mix4_InSol_TiO2_1 5653 61563 37311 Mix4_TiO2_1_4 4704 P54646;Q13131-2;Q13131 P54646;Q13131-2 Q13131-2 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2;>sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_ 0.587632 4.21461 5.24358E-09 -82.1123 1.46771E-12 140.03 0 0 0.587632 4.21461 0.459606 31.17 1 S LRTSCGSPNYAAP CK1;Proline-directed 0.05 1.46771E-12 140.03 _TSCGpSPNYAAPEVISGR_ T(0.184)S(0.223)CGS(0.588)PNY(0.006)AAPEVISGR T(-5.05)S(-4.21)CGS(4.21)PNY(-20.13)AAPEVIS(-31.17)GR 5 2 923.39549 -0.70533 68418 0 0 0 0 0 68418 0 903 665 769 769 2008;2009 2274;2276;2277 18405 11175 Mix4_TiO2_2_2 4812 18409 11179 Mix4_TiO2_Reinj_1_5 5189 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.984255 17.9654 0.879895 8.64887 1.37452E-38 219.69 0.984255 17.9654 3.51501E-10 129.8 0.87121 8.31847 4.16059E-48 247.82 0 0 0.909045 9.99765 9.58262E-17 142.64 0.970842 15.2557 0.000151466 97.062 1 S RFLEENSSDPTYT 4.16059E-48 247.82 _FLEENpSSDPTYTSSLGGK_ FLEENS(0.984)S(0.016)DPTYTSSLGGK FLEENS(17.97)S(-17.97)DPT(-46.91)Y(-68.58)T(-88.43)S(-116.35)S(-115.74)LGGK 6 2 1006.4303 0.95092 1984800 19.042 936560 30992 0 24245 0 662350 330680 904 665 770 770 2008;2009 2274;2276;2277 18411 11181 Mix4_TiO2_Reinj_1_5 5780 18409 11179 Mix4_TiO2_Reinj_1_5 5189 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.99545 26.0447 0.126932 -8.37442 1.37452E-38 219.69 0.0157243 -17.9654 3.51501E-10 129.8 0.99545 26.0447 4.16059E-48 247.82 0 0 0.424184 0 9.58262E-17 142.64 0.429973 -0.838902 0.000151466 97.062 1 S FLEENSSDPTYTS 4.16059E-48 247.82 _FLEENSpSDPTYTSSLGGK_ FLEENS(0.002)S(0.995)DPT(0.002)YTSSLGGK FLEENS(-27.51)S(26.04)DPT(-26.04)Y(-35.07)T(-61.46)S(-86.74)S(-101.17)LGGK 7 2 1006.4303 0.13061 725420 6.9596 0 0 0 725420 0 0 0 905 665 777 777 2008;2009 2274;2276;2277 18410 11180 Mix4_TiO2_Reinj_1_5 5465 18409 11179 Mix4_TiO2_Reinj_1_5 5189 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.996713 24.83 0.981498 17.2477 1.37452E-38 219.69 2.62771E-12 -115.735 3.51501E-10 129.8 0.996713 24.83 4.16059E-48 247.82 0 0 0.00222656 -22.7992 9.58262E-17 142.64 0.0283579 -11.4197 0.000151466 97.062 1 S DPTYTSSLGGKIP CK1 0.143 4.16059E-48 247.82 _FLEENSSDPTYTSpSLGGK_ FLEENSSDPTYTS(0.003)S(0.997)LGGK FLEENS(-123.83)S(-100.57)DPT(-79.39)Y(-72.21)T(-50.33)S(-24.83)S(24.83)LGGK 14 2 1006.4303 0.80424 865810 8.3065 159610 0 0 706200 0 0 0 906 669 3 3 492 557 4543 2748 Mix4_TiO2_1_3 5576 4543 2748 Mix4_TiO2_1_3 5576 P55072 P55072 P55072 >sp|P55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase OS=Homo sapiens GN=VCP PE=1 SV=4 0.874937 8.4485 0.874937 8.4485 0.0208245 63.406 0 0 1 S ____MASGADSKG CK2;GSK3 0.081 0.0208245 63.406 _(ac)ApSGADSKGDDLSTAILK_ AS(0.875)GADS(0.125)KGDDLSTAILK AS(8.45)GADS(-8.45)KGDDLS(-63.41)T(-63.41)AILK 2 2 885.9115 2.3056 41953 0.33818 41953 0 0 0 0 0 0 907 669 784 784 2035 2307 18606 11329 Mix4_TiO2_1_3 5479 18606 11329 Mix4_TiO2_1_3 5479 P55072 P55072 P55072 >sp|P55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase OS=Homo sapiens GN=VCP PE=1 SV=4 0.384247 0 0.384247 0 0.136108 59.635 1 S QGGAGPSQGSGGG 0.136108 59.635 _FPSGNQGGAGPpSQGSGGGTGGSVYTEDNDDDLYG_ FPS(0.217)GNQGGAGPS(0.384)QGS(0.384)GGGT(0.013)GGS(0.001)VYTEDNDDDLYG FPS(-2.49)GNQGGAGPS(0)QGS(0)GGGT(-14.58)GGS(-25.18)VY(-34.9)T(-39.65)EDNDDDLY(-59.63)G 12 3 1100.7673 -0.98142 0 0 0 0 0 0 0 0 0 908 669 787 787 2035 2307 18606 11329 Mix4_TiO2_1_3 5479 18606 11329 Mix4_TiO2_1_3 5479 P55072 P55072 P55072 >sp|P55072|TERA_HUMAN Transitional endoplasmic reticulum ATPase OS=Homo sapiens GN=VCP PE=1 SV=4 0.384247 0 0.384247 0 0.136108 59.635 1 S AGPSQGSGGGTGG CK1 0.081 0.136108 59.635 _FPSGNQGGAGPpSQGSGGGTGGSVYTEDNDDDLYG_ FPS(0.217)GNQGGAGPS(0.384)QGS(0.384)GGGT(0.013)GGS(0.001)VYTEDNDDDLYG FPS(-2.49)GNQGGAGPS(0)QGS(0)GGGT(-14.58)GGS(-25.18)VY(-34.9)T(-39.65)EDNDDDLY(-59.63)G 15 3 1100.7673 -0.98142 0 0 0 0 0 0 0 0 0 909 671 384 384 3224 3656 30530 18969 Mix4_InSol_Tio2_Reinj_1 2481 30529 18968 Mix4_InSol_TiO2_1 2458 P55085 P55085 P55085 >sp|P55085|PAR2_HUMAN Proteinase-activated receptor 2 OS=Homo sapiens GN=F2RL1 PE=1 SV=1 0.918772 13.1319 0.804841 7.42848 0.271368 29.767 0.744582 8.02669 0.0135469 69.046 0 0 0.802473 6.14018 0.00243962 90.247 0.918772 13.1319 0.0717139 46.445 1 S KHSRKSSSYSSSS CAMK2;CK1;GSK3;PKA 0.004788 0.00243962 90.247 _KSpSSYSSSSTTVK_ KS(0.045)S(0.919)S(0.025)YS(0.002)S(0.009)SSTTVK KS(-13.13)S(13.13)S(-15.66)Y(-34.92)S(-27.07)S(-20.18)S(-40.31)S(-39.29)T(-33.54)T(-41.15)VK 3 2 714.81634 0.33104 452110 34406 0 0 225790 0 95852 96060 910 671 387 387 3224 3656 30533 18972 Mix4_TiO2_Reinj_1_3 2158 30529 18968 Mix4_InSol_TiO2_1 2458 P55085 P55085 P55085 >sp|P55085|PAR2_HUMAN Proteinase-activated receptor 2 OS=Homo sapiens GN=F2RL1 PE=1 SV=1 0.408123 0 0.00854132 -19.7418 0.271368 29.767 0.408123 0 0.0135469 69.046 0 0 0.000269539 -34.7381 0.00243962 90.247 0.00180446 -27.0686 0.0717139 46.445 1 S RKSSSYSSSSTTV CK1 0.081 0.00243962 90.247 _KSSSYpSSSSTTVK_ KS(0.005)S(0.123)S(0.005)YS(0.408)S(0.408)S(0.049)S(0.001)TTVK KS(-19.19)S(-5.22)S(-19.19)Y(-32.42)S(0)S(0)S(-9.18)S(-25.47)T(-30.6)T(-30.6)VK 6 2 714.81634 -0.0072894 0 0 0 0 0 0 0 0 911 671 388 388 3224 3656 30533 18972 Mix4_TiO2_Reinj_1_3 2158 30529 18968 Mix4_InSol_TiO2_1 2458 P55085 P55085 P55085 >sp|P55085|PAR2_HUMAN Proteinase-activated receptor 2 OS=Homo sapiens GN=F2RL1 PE=1 SV=1 0.408123 0 0.00138966 -27.628 0.271368 29.767 0.408123 0 0.0135469 69.046 0 0 0.000573242 -31.4609 0.00243962 90.247 0.0088131 -20.1808 0.0717139 46.445 1 S KSSSYSSSSTTVK CK1 0.081 0.00243962 90.247 _KSSSYpSSSSTTVK_ KS(0.005)S(0.123)S(0.005)YS(0.408)S(0.408)S(0.049)S(0.001)TTVK KS(-19.19)S(-5.22)S(-19.19)Y(-32.42)S(0)S(0)S(-9.18)S(-25.47)T(-30.6)T(-30.6)VK 7 2 714.81634 -0.0072894 0 0 0 0 0 0 0 0 912 672 10 10 120 141 1242 790 Mix4_TiO2_1_4 8323 1242 790 Mix4_TiO2_1_4 8323 P55209 P55209 P55209 >sp|P55209|NP1L1_HUMAN Nucleosome assembly protein 1-like 1 OS=Homo sapiens GN=NAP1L1 PE=1 SV=1 1 73.1782 1 73.1782 0.000321325 81.021 0 0 1 S IDNKEQSELDQDL CK2 0.117 0.000321325 81.021 _(ac)ADIDNKEQpSELDQDLDDVEEVEEEETGEETK_ ADIDNKEQS(1)ELDQDLDDVEEVEEEETGEETK ADIDNKEQS(73.18)ELDQDLDDVEEVEEEET(-73.18)GEET(-76.45)K 9 3 1234.8406 0.63539 96326 0.019287 96326 0 0 0 0 0 0 913 678 117 117 5186 5904 50217 30698 Mix4_InSol_TiO2_1 3162 50221 30702 Mix4_TiO2_Reinj_1_5 2953 P55884-2;P55884 P55884-2 P55884-2 >sp|P55884-2|EIF3B_HUMAN Isoform 2 of Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens GN=EIF3B;>sp|P55884|EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens GN=EIF3B PE=1 SV=3 0.498603 0 0.0862228 -10.2522 3.52716E-06 108.22 0.0808749 -10.5556 6.11194E-10 124.2 0.498603 0 0.00403676 77.382 0.107542 -9.19009 0.001499 80.631 1 S QARDERSDSRAQA 6.11194E-10 124.2 _pSDSRAQAVSEDAGGNEGR_ S(0.499)DS(0.499)RAQAVS(0.003)EDAGGNEGR S(0)DS(0)RAQAVS(-22.51)EDAGGNEGR 1 3 629.26059 0.96818 0 0 0 0 0 0 0 0 914 678 119 119 5186 5904 50221 30702 Mix4_TiO2_Reinj_1_5 2953 50221 30702 Mix4_TiO2_Reinj_1_5 2953 P55884-2;P55884 P55884-2 P55884-2 >sp|P55884-2|EIF3B_HUMAN Isoform 2 of Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens GN=EIF3B;>sp|P55884|EIF3B_HUMAN Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens GN=EIF3B PE=1 SV=3 0.920729 10.6502 0.913777 10.2522 3.52716E-06 108.22 0.920729 10.6502 6.11194E-10 124.2 0.544733 0.779176 0.00403676 77.382 0.892458 9.19009 0.001499 80.631 1 S RDERSDSRAQAVS CAMK2 0.042 6.11194E-10 124.2 _SDpSRAQAVSEDAGGNEGR_ S(0.079)DS(0.921)RAQAVSEDAGGNEGR S(-10.65)DS(10.65)RAQAVS(-79.85)EDAGGNEGR 3 3 629.26059 -0.3906 686520 64608 0 0 456070 0 80016 85827 915 681 228 228 5669 6455 55466 33970 Mix4_TiO2_Reinj_1_6 6699 55466 33970 Mix4_TiO2_Reinj_1_6 6699 P56749 P56749 P56749 >sp|P56749|CLD12_HUMAN Claudin-12 OS=Homo sapiens GN=CLDN12 PE=1 SV=1 0.918688 10.5302 0.293484 -3.8153 0.0812248 51.988 0.918688 10.5302 0.0110745 71.785 1 S QPYSARSRLSAIE CK1 0.081 0.0110745 71.785 _pSRLSAIEIDIPVVSHTT_ S(0.919)RLS(0.081)AIEIDIPVVSHTT S(10.53)RLS(-10.53)AIEIDIPVVS(-71.79)HT(-71.79)T(-71.79) 1 3 639.99423 -0.41279 17523 0 0 0 17523 0 0 0 916 681 231 231 5669 6455 55465 33969 Mix4_TiO2_1_6 5876 55466 33970 Mix4_TiO2_Reinj_1_6 6699 P56749 P56749 P56749 >sp|P56749|CLD12_HUMAN Claudin-12 OS=Homo sapiens GN=CLDN12 PE=1 SV=1 0.706503 3.8153 0.706503 3.8153 0.0812248 51.988 0.0813113 -10.5302 0.0110745 71.785 1 S SARSRLSAIEIDI CK1;CK2;PKA 0.042 0.0110745 71.785 _SRLpSAIEIDIPVVSHTT_ S(0.293)RLS(0.707)AIEIDIPVVSHTT S(-3.82)RLS(3.82)AIEIDIPVVS(-51.99)HT(-51.99)T(-51.99) 4 2 959.48771 -0.074991 10992 10992 0 0 0 0 0 0 917 682 437 437 4457 5068 42340 26046 Mix4_TiO2_Reinj_1_3 8482 42340 26046 Mix4_TiO2_Reinj_1_3 8482 P57059 P57059 P57059 >sp|P57059|SIK1_HUMAN Serine/threonine-protein kinase SIK1 OS=Homo sapiens GN=SIK1 PE=1 SV=2 0.897157 9.81 0.51589 0.431506 0.000653868 92.635 0.897157 9.81 1.04018E-12 144.87 1 S PRPVSPSSLLDTA 1.04018E-12 144.87 _PVSPpSSLLDTAISEEAR_ PVS(0.094)PS(0.897)S(0.009)LLDTAISEEAR PVS(-9.81)PS(9.81)S(-19.93)LLDT(-64.11)AIS(-108.61)EEAR 5 2 926.44042 0.1945 227570 75209 0 0 152360 0 0 0 918 682 438 438 4457 5068 42338 26044 Mix4_TiO2_1_3 7866 42340 26046 Mix4_TiO2_Reinj_1_3 8482 P57059 P57059 P57059 >sp|P57059|SIK1_HUMAN Serine/threonine-protein kinase SIK1 OS=Homo sapiens GN=SIK1 PE=1 SV=2 0.343346 0 0.343346 0 0.000653868 92.635 0.333318 0 1.04018E-12 144.87 1 S RPVSPSSLLDTAI CK1;CK2 0.081 1.04018E-12 144.87 _PVSPpSSLLDTAISEEAR_ PVS(0.313)PS(0.343)S(0.343)LLDT(0.001)AISEEAR PVS(-0.41)PS(0)S(0)LLDT(-26.62)AIS(-92.64)EEAR 6 3 617.96271 1.4145 0 0 0 0 0 0 0 0 919 682 575 575 4810 5460 45897 28067 Mix4_TiO2_Reinj_1_3 4387 45897 28067 Mix4_TiO2_Reinj_1_3 4387 P57059 P57059 P57059 >sp|P57059|SIK1_HUMAN Serine/threonine-protein kinase SIK1 OS=Homo sapiens GN=SIK1 PE=1 SV=2 0.994772 25.1022 0.971641 15.9465 0.0135022 66.906 0 0 0.994772 25.1022 0.00808082 76.698 0 0 0 0 1 S QEGRRASDTSLTQ CAMK2;PKA;PKA/AKT 0.00111111 0.00808082 76.698 _RApSDTSLTQGLK_ RAS(0.995)DT(0.002)S(0.003)LTQGLK RAS(25.1)DT(-26.65)S(-25.1)LT(-52.22)QGLK 3 2 678.82958 0.13923 804000 233450 0 0 570550 0 0 0 920 685 86 86 4671 5301 44277 27091 Mix4_TiO2_Reinj_1_5 6386 44277 27091 Mix4_TiO2_Reinj_1_5 6386 P57740 P57740 P57740 >sp|P57740|NU107_HUMAN Nuclear pore complex protein Nup107 OS=Homo sapiens GN=NUP107 PE=1 SV=1 0.998152 28.483 0.996745 25.5704 0.186915 39.685 0.998152 28.483 0.139077 42.759 0 0 0 0 1 S LGTGGKSPRLTQS CDK1;CK1;Proline-directed 0.0057 0.139077 42.759 _QPDISCILGTGGKpSPR_ QPDISCILGT(0.001)GGKS(0.998)PR QPDIS(-33.63)CILGT(-28.48)GGKS(28.48)PR 14 3 589.2816 -0.35107 926460 194610 0 0 731850 0 0 0 921 685 11 11 5295 6028 51414 31488 Mix4_TiO2_Reinj_1_3 6552 51415 31489 Mix4_TiO2_Reinj_1_5 6488 P57740 P57740 P57740 >sp|P57740|NU107_HUMAN Nuclear pore complex protein Nup107 OS=Homo sapiens GN=NUP107 PE=1 SV=1 0.868133 8.18587 0.862764 7.98524 0.014267 65.525 0.868133 8.18587 0.00775369 77.289 0.849729 7.57346 0.257711 26.988 0 0 1 S GFGEISSPVIREA Polo box;Proline-directed 0.00405 0.00775369 77.289 _SGFGEISpSPVIR_ SGFGEIS(0.132)S(0.868)PVIR S(-43.2)GFGEIS(-8.19)S(8.19)PVIR 8 2 664.81594 0.42558 488040 93115 0 0 347260 0 47667 0 922 687 21 21 3191 3621 30301 18851 Mix4_TiO2_Reinj_1_6 6504 30301 18851 Mix4_TiO2_Reinj_1_6 6504 P60174;P60174-2 P60174 P60174 >sp|P60174|TPIS_HUMAN Triosephosphate isomerase OS=Homo sapiens GN=TPI1 PE=1 SV=2;>sp|P60174-2|TPIS_HUMAN Isoform 2 of Triosephosphate isomerase OS=Homo sapiens GN=TPI1 0.999982 47.5284 0 0 0.999982 47.5284 0.00263439 81.579 1 S MNGRKQSLGELIG AURORA;AURORA-1;AURORA-A;CAMK2;CK2;PKA 0.004788 0.00263439 81.579 _KQpSLGELIGTLNAAK_ KQS(1)LGELIGTLNAAK KQS(47.53)LGELIGT(-47.53)LNAAK 3 2 811.92929 0.33159 108300 0 0 0 108300 0 0 0 923 689 7 7 4415;4416 5023;5024 42010 25909 Mix4_TiO2_Reinj_1_6 2338 42002 25900 Mix4_InSol_TiO2_1 2987 P60468 P60468 P60468 >sp|P60468|SC61B_HUMAN Protein transport protein Sec61 subunit beta OS=Homo sapiens GN=SEC61B PE=1 SV=2 0.35855 2.42131 0.100472 -4.86409 1.19343 14.077 0 0 0.35855 2.42131 0.447227 33.943 0.0346891 -10.4924 2.39429E-06 107.44 0.272713 -0.838005 0.000474947 90.763 1 S MPGPTPSGTNVGS 2.39429E-06 107.44 _PGPTPpSGTNVGSSGRSPSK_ PGPT(0.034)PS(0.359)GT(0.083)NVGS(0.205)S(0.205)GRS(0.079)PS(0.034)K PGPT(-10.19)PS(2.42)GT(-6.35)NVGS(-2.42)S(-2.42)GRS(-6.57)PS(-10.19)K 6 2 925.42564 0.19277 0 0 0 0 0 0 0 0 924 689 13 13 4415;4416 5023;5024 42007 25906 Mix4_TiO2_1_6 1886 42002 25900 Mix4_InSol_TiO2_1 2987 P60468 P60468 P60468 >sp|P60468|SC61B_HUMAN Protein transport protein Sec61 subunit beta OS=Homo sapiens GN=SEC61B PE=1 SV=2 0.674786 5.72261 0.674786 5.72261 1.19343 14.077 0 0 0.426385 5.91493 0.447227 33.943 0.185621 -2.32565 2.39429E-06 107.44 0.575812 2.49492 0.000474947 90.763 1 S SGTNVGSSGRSPS CK1;GSK3 0.081 2.39429E-06 107.44 _PGPTPSGTNVGpSSGRSPSK_ PGPT(0.026)PS(0.026)GT(0.039)NVGS(0.675)S(0.181)GRS(0.026)PS(0.026)K PGPT(-14.08)PS(-14.08)GT(-12.38)NVGS(5.72)S(-5.72)GRS(-14.08)PS(-14.08)K 12 2 925.42564 1.115 1708300 12545 0 0 0 0 0 1695700 925 689 14 14 4415;4416 5023;5024 42043 25911 Mix4_InSol_TiO2_1 3718 42002 25900 Mix4_InSol_TiO2_1 2987 P60468 P60468 P60468 >sp|P60468|SC61B_HUMAN Protein transport protein Sec61 subunit beta OS=Homo sapiens GN=SEC61B PE=1 SV=2 0.665517 7.00816 0.180678 -5.72261 1.19343 14.077 0 0 0.205314 -2.42131 0.447227 33.943 0.665517 7.00816 2.39429E-06 107.44 0.322129 0 0.000474947 90.763 1 S GTNVGSSGRSPSK 2.39429E-06 107.44 _PGPTPSGTNVGSpSGRSPSKAVAAR_ PGPT(0.001)PS(0.029)GT(0.029)NVGS(0.133)S(0.666)GRS(0.118)PS(0.025)KAVAAR PGPT(-26.6)PS(-13.67)GT(-13.67)NVGS(-7.01)S(7.01)GRS(-7.5)PS(-14.25)KAVAAR 13 3 773.37981 0.00096434 5498100 0 0 0 0 0 5498100 0 926 689 17 17 4415;4416 5023;5024 42003 25902 Mix4_InSol_TiO2_1 3062 42002 25900 Mix4_InSol_TiO2_1 2987 P60468 P60468 P60468 >sp|P60468|SC61B_HUMAN Protein transport protein Sec61 subunit beta OS=Homo sapiens GN=SEC61B PE=1 SV=2 0.963443 14.6235 0.307932 2.10372 1.19343 14.077 0 0 0.747139 6.32168 0.447227 33.943 0.963443 14.6235 2.39429E-06 107.44 0.324182 -2.49492 0.000474947 90.763 1 S VGSSGRSPSKAVA CDK1;CDK2;CK1;Proline-directed 0.0057 2.39429E-06 107.44 _PGPTPSGTNVGSSGRpSPSK_ PGPT(0.001)PS(0.001)GT(0.001)NVGS(0.001)S(0.001)GRS(0.963)PS(0.033)K PGPT(-32.27)PS(-32.27)GT(-32.27)NVGS(-30.76)S(-30.76)GRS(14.62)PS(-14.62)K 16 3 617.28618 -0.62169 2552800 0 0 0 164820 0 2387900 0 927 689 19 19 4415;4416 5023;5024 42002 25900 Mix4_InSol_TiO2_1 2987 42002 25900 Mix4_InSol_TiO2_1 2987 P60468 P60468 P60468 >sp|P60468|SC61B_HUMAN Protein transport protein Sec61 subunit beta OS=Homo sapiens GN=SEC61B PE=1 SV=2 0.938694 12.9825 0.189707 -2.10372 1.19343 14.077 0 0 0.174274 -6.32168 0.447227 33.943 0.938694 12.9825 2.39429E-06 107.44 0.679796 3.32892 0.000474947 90.763 1 S SSGRSPSKAVAAR CAMK2 0.042 2.39429E-06 107.44 _PGPTPSGTNVGSSGRSPpSK_ PGPTPSGTNVGS(0.002)S(0.012)GRS(0.047)PS(0.939)K PGPT(-65.81)PS(-41.75)GT(-40.76)NVGS(-26.98)S(-18.92)GRS(-12.98)PS(12.98)K 18 2 925.42564 -0.31739 3286500 0 0 0 0 0 1671000 1615500 928 690 3 3 500 566 4647 2816 Mix4_InSol_Tio2_Reinj_1 5451 4646 2814 Mix4_InSol_TiO2_1 5538 P60981 P60981 P60981 >sp|P60981|DEST_HUMAN Destrin OS=Homo sapiens GN=DSTN PE=1 SV=3 1 115.196 0 0 1 127.637 7.09042E-05 127.64 1 115.196 0.000279424 115.2 1 S ____MASGVQVAD 7.09042E-05 127.64 _(ac)ApSGVQVADEVCR_ AS(1)GVQVADEVCR AS(115.2)GVQVADEVCR 2 2 706.79742 0.086041 750470 0 0 0 0 0 341300 409160 929 696 263 263 119 138 1231 786 Mix4_TiO2_Reinj_1_2 4293 1231 786 Mix4_TiO2_Reinj_1_2 4293 P61247 P61247 P61247 >sp|P61247|RS3A_HUMAN 40S ribosomal protein S3a OS=Homo sapiens GN=RPS3A PE=1 SV=2 1 70.5928 0.571628 1.25293 0.783041 1.2529 0 0 1 70.5928 0.011461 70.593 0 0 1 S EPPVQESV_____ 0.011461 70.593 _ADGYEPPVQEpSV_ ADGYEPPVQES(1)V ADGY(-70.59)EPPVQES(70.59)V 11 2 685.77922 0.14999 160260 1.4893 33662 0 0 126600 0 0 0 930 697 97 97 5462 6216 53311 32574 Mix4_TiO2_Reinj_1_6 3432 53312 32575 Mix4_TiO2_Reinj_1_6 3941 P61313 P61313 P61313 >sp|P61313|RL15_HUMAN 60S ribosomal protein L15 OS=Homo sapiens GN=RPL15 PE=1 SV=2 0.999661 34.692 0.997054 25.2943 0.0254328 54.833 0 0 0.999661 34.692 0.00527842 67.974 1 S QLKFARSLQSVAE 0.00527842 67.974 _pSLQSVAEER_ S(1)LQSVAEER S(34.69)LQS(-34.69)VAEER 1 2 549.74499 0.29924 54189 0.014937 13796 0 0 40392 0 0 0 931 697 100 100 5462 6216 53312 32575 Mix4_TiO2_Reinj_1_6 3941 53312 32575 Mix4_TiO2_Reinj_1_6 3941 P61313 P61313 P61313 >sp|P61313|RL15_HUMAN 60S ribosomal protein L15 OS=Homo sapiens GN=RPL15 PE=1 SV=2 0.999997 55.7139 0.999997 54.8329 0.0254328 54.833 0 0 0.999997 55.7139 0.00527842 67.974 1 S FARSLQSVAEERA CK1;CK2 0.081 0.00527842 67.974 _SLQpSVAEER_ SLQS(1)VAEER S(-55.71)LQS(55.71)VAEER 4 2 549.74499 0.30886 37254 0.010269 9028.2 0 0 28226 0 0 0 932 702 186 186 2041;2042;3023;3024 2314;2315;3437;3438 28840 17948 Mix4_TiO2_Reinj_1_6 2834 28837 17946 Mix4_TiO2_Reinj_1_6 3023 P62070 P62070 P62070 >sp|P62070|RRAS2_HUMAN Ras-related protein R-Ras2 OS=Homo sapiens GN=RRAS2 PE=1 SV=1 0.99999 49.8006 0.991032 20.4339 0.0115271 71.862 0 0 0.99999 49.8006 6.66702E-08 135.66 0.966902 14.6558 0.27937 35.01 0 0 1 S EQECPPSPEPTRK ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 6.66702E-08 135.66 _KFQEQECPPpSPEPTRK_ KFQEQECPPS(1)PEPTRK KFQEQECPPS(49.8)PEPT(-49.8)RK 10 3 679.97484 -0.11416 1083800 82655 0 0 962540 0 38556 0 933 712 240 240 3734;3735;4957 4211;4212;4213;5636;5637 35242 21792 Mix4_InSol_Tio2_Reinj_1 2997 35223 21787 Mix4_InSol_TiO2_1 3284 P62753 P62753 P62753 >sp|P62753|RS6_HUMAN 40S ribosomal protein S6 OS=Homo sapiens GN=RPS6 PE=1 SV=1 0.750369 6.88292 0 0 0 0 0.951314 14.2171 0.147173 34.852 0.706413 8.85441 0.00642374 62.046 0.750369 6.88292 0.0812265 39.628 1 S LSSLRASTSKSES CK1;GSK3;NEK6;PKA 0.042 0.00642374 62.046 _LSSLRApSTSKSESSQK_ LS(0.154)S(0.029)LRAS(0.75)T(0.038)S(0.021)KS(0.003)ES(0.002)S(0.002)QK LS(-6.88)S(-14.08)LRAS(6.88)T(-12.93)S(-15.59)KS(-24.18)ES(-25.04)S(-25.04)QK 7 2 888.43039 -0.64976 383930 0 0 0 0 0 257780 126150 934 719;882 264;260 260 5033 5724 48598 29708 Mix4_TiO2_Reinj_1_4 2817 48597 29706 Mix4_TiO2_Reinj_1_4 2763 P62995;P62995-3;Q13595 P62995;Q13595 Q13595 >sp|P62995|TRA2B_HUMAN Transformer-2 protein homolog beta OS=Homo sapiens GN=TRA2B PE=1 SV=1;>sp|P62995-3|TRA2B_HUMAN Isoform HTRA2-beta3 of Transformer-2 protein homolog beta OS=Homo sapiens GN=TRA2B;>sp|Q13595|TRA2A_HUMAN Transformer-2 protein homolog al 0.999681 42.7404 0.999681 42.7404 0.000770481 79.757 0.408603 0.560201 0.770817 0.5602 2 S QIYRRRSPSPYYS;YRYRRRSPSPYYS CAMK2;CHK1;PKA;PKA/AKT;PKD;Proline-directed 0.00111111 0.000770481 79.757 _RRpSPpSPYYSR_ RRS(1)PS(1)PYYSR RRS(42.74)PS(42.74)PY(-42.74)Y(-42.74)S(-42.74)R 3 3 476.86555 -0.27676 3793800 0 0 0 3793800 0 0 0 935 719;882 266;262 262 5033 5724 48598 29708 Mix4_TiO2_Reinj_1_4 2817 48597 29706 Mix4_TiO2_Reinj_1_4 2763 P62995;P62995-3;Q13595 P62995;Q13595 Q13595 >sp|P62995|TRA2B_HUMAN Transformer-2 protein homolog beta OS=Homo sapiens GN=TRA2B PE=1 SV=1;>sp|P62995-3|TRA2B_HUMAN Isoform HTRA2-beta3 of Transformer-2 protein homolog beta OS=Homo sapiens GN=TRA2B;>sp|Q13595|TRA2A_HUMAN Transformer-2 protein homolog al 0.999681 42.7404 0.999681 42.7404 0.000770481 79.757 0.395032 -0.526513 0.770817 0.5602 2 S YRRRSPSPYYSRG;YRRRSPSPYYSRY CAMK2;GSK3;PKA/AKT;Proline-directed 0.001764 0.000770481 79.757 _RRpSPpSPYYSR_ RRS(1)PS(1)PYYSR RRS(42.74)PS(42.74)PY(-42.74)Y(-42.74)S(-42.74)R 5 3 476.86555 -0.27676 6193600 0 0 0 6193600 0 0 0 936 723 2 2 5175 5891 50126 30636 Mix4_TiO2_1_3 2649 50127 30637 Mix4_TiO2_Reinj_1_3 3217 P63165 P63165 P63165 >sp|P63165|SUMO1_HUMAN Small ubiquitin-related modifier 1 OS=Homo sapiens GN=SUMO1 PE=1 SV=1 0.990546 23.2129 0.990546 23.2129 0.00192423 83.872 0.989845 22.8993 2.06836E-05 98.771 1 S _____MSDQEAKP CK2 0.117 2.06836E-05 98.771 _(ac)pSDQEAKPSTEDLGDKK_ S(0.991)DQEAKPS(0.005)T(0.005)EDLGDKK S(23.21)DQEAKPS(-23.21)T(-23.21)EDLGDKK 1 2 935.40932 -0.17568 370780 104560 0 0 266220 0 0 0 937 728 314 314 31 39 328 182 Mix4_InSol_Tio2_Reinj_1 3159 329 185 Mix4_TiO2_1_4 2541 P67809 P67809 P67809 >sp|P67809|YBOX1_HUMAN Nuclease-sensitive element-binding protein 1 OS=Homo sapiens GN=YBX1 PE=1 SV=3 0.994065 22.2398 0.881885 8.73107 9.58397E-11 129.03 0.863789 8.02197 2.1592E-10 118.61 0.953066 13.0763 1.08285E-10 127.95 0.994065 22.2398 6.14186E-07 111.95 1 S PPAENSSAPEAEQ CK2 0.117 9.58397E-11 129.03 _AADPPAENSpSAPEAEQGGAE_ AADPPAENS(0.006)S(0.994)APEAEQGGAE AADPPAENS(-22.24)S(22.24)APEAEQGGAE 10 2 989.38911 0.5491 577950 0.033419 102730 0 0 253890 0 98807 122530 938 728 174 174 3997;4401 4554;5006 37848 23223 Mix4_TiO2_1_4 1694 41818 25745 Mix4_TiO2_Reinj_1_4 3204 P67809 P67809 P67809 >sp|P67809|YBOX1_HUMAN Nuclease-sensitive element-binding protein 1 OS=Homo sapiens GN=YBX1 PE=1 SV=3 0.991988 20.9277 0.991988 20.9277 9.37071E-08 107.59 0.751372 4.80306 9.7034E-13 132.98 0.00124819 -28.0537 2.41233E-12 126.42 0.0016096 -23.8749 0.000174045 87.687 1 S GEKNEGSESAPEG 9.7034E-13 132.98 _NEGpSESAPEGQAQQR_ NEGS(0.992)ES(0.008)APEGQAQQR NEGS(20.93)ES(-20.93)APEGQAQQR 4 2 834.33649 0.26525 91146 0.0017716 22360 0 0 68787 0 0 0 939 728 176 176 3997;4401 4554;5006 41818 25745 Mix4_TiO2_Reinj_1_4 3204 41818 25745 Mix4_TiO2_Reinj_1_4 3204 P67809 P67809 P67809 >sp|P67809|YBOX1_HUMAN Nuclease-sensitive element-binding protein 1 OS=Homo sapiens GN=YBX1 PE=1 SV=3 0.493376 0 0.00801196 -20.9277 9.37071E-08 107.59 0.493376 0 9.7034E-13 132.98 4.75248E-05 -42.2473 2.41233E-12 126.42 4.20255E-05 -39.707 0.000174045 87.687 1 S KNEGSESAPEGQA CK2 0.117 9.7034E-13 132.98 _NYQQNYQNSESGEKNEGpSESAPEGQAQQR_ NYQQNYQNS(0.001)ES(0.013)GEKNEGS(0.493)ES(0.493)APEGQAQQR NY(-88.51)QQNY(-36.62)QNS(-29.84)ES(-15.92)GEKNEGS(0)ES(0)APEGQAQQR 20 3 1113.1257 -1.6139 0 0 0 0 0 0 0 0 0 940 728 167 167 4401 5006 41815 25736 Mix4_InSol_TiO2_1 3493 41818 25745 Mix4_TiO2_Reinj_1_4 3204 P67809 P67809 P67809 >sp|P67809|YBOX1_HUMAN Nuclease-sensitive element-binding protein 1 OS=Homo sapiens GN=YBX1 PE=1 SV=3 0.79736 6.68448 0.601589 4.33918 9.37071E-08 107.59 0.0867809 -7.02992 9.7034E-13 132.98 0.79736 6.68448 2.41233E-12 126.42 0.302614 -1.13321 0.000174045 87.687 1 S NYQNSESGEKNEG 9.7034E-13 132.98 _NYQQNYQNSEpSGEKNEGSESAPEGQAQQR_ NYQQNY(0.03)QNS(0.171)ES(0.797)GEKNEGS(0.001)ESAPEGQAQQR NY(-45.21)QQNY(-14.21)QNS(-6.68)ES(6.68)GEKNEGS(-28.05)ES(-42.25)APEGQAQQR 11 3 1113.1257 -0.28107 821930 0.016733 480140 0 0 0 0 341790 0 941 729 205 205 2785 3174;3175 26646 16666 Mix4_TiO2_Reinj_1_6 5381 26647 16668 Mix4_TiO2_Reinj_1_6 5386 P67870 P67870 P67870 >sp|P67870|CSK2B_HUMAN Casein kinase II subunit beta OS=Homo sapiens GN=CSNK2B PE=1 SV=1 0.867085 8.14489 0.185411 -6.32855 0.000363217 86.271 0.0392872 -13.8492 0.608644 32.835 0.867085 8.14489 1.33963E-23 158.77 0.139004 -7.91819 0.529159 34.459 0.5 0 5.73138E-11 123.34 0.495063 0 4.76785E-07 108.69 1 S LQLQAASNFKSPV GSK3 0.081 1.33963E-23 158.77 _IHPM(ox)AYQLQLQAApSNFKSPVK_ IHPMAYQLQLQAAS(0.867)NFKS(0.133)PVK IHPMAY(-102.53)QLQLQAAS(8.14)NFKS(-8.14)PVK 14 4 617.56054 -0.1188 897010 0 0 0 701030 0 195980 0 942 729 209 209 2785 3174;3175 26672 16678 Mix4_InSol_TiO2_1 7534 26647 16668 Mix4_TiO2_Reinj_1_6 5386 P67870 P67870 P67870 >sp|P67870|CSK2B_HUMAN Casein kinase II subunit beta OS=Homo sapiens GN=CSNK2B PE=1 SV=1 0.999999 62.8384 0.999891 39.6216 0.000363217 86.271 0.953182 13.8492 0.608644 32.835 0.999999 61.0446 1.33963E-23 158.77 0.994625 23.0223 0.529159 34.459 0.999999 62.8384 5.73138E-11 123.34 0.999994 52.3671 4.76785E-07 108.69 1 S AASNFKSPVKTIR CDK1;CDK2;CK1;Proline-directed 0.0057 1.33963E-23 158.77 _IHPMAYQLQLQAASNFKpSPVK_ IHPMAYQLQLQAASNFKS(1)PVK IHPMAY(-123.34)QLQLQAAS(-62.84)NFKS(62.84)PVK 18 2 1226.1164 0.47437 36566000 731930 70663 0 12667000 291160 11995000 10810000 943 732;1503 48;48 48 6026 6872 59522 36118 Mix4_TiO2_1_4 7047 59522 36118 Mix4_TiO2_1_4 7047 P68363;Q71U36;CON__ENSEMBL:ENSBTAP00000016242;Q13748;Q13748-2;Q6PEY2;Q9BQE3 P68363;Q9BQE3 P68363 >sp|P68363|TBA1B_HUMAN Tubulin alpha-1B chain OS=Homo sapiens GN=TUBA1B PE=1 SV=1;>sp|Q71U36|TBA1A_HUMAN Tubulin alpha-1A chain OS=Homo sapiens GN=TUBA1A PE=1 SV=1;>ENSEMBL:ENSBTAP00000016242 (Bos taurus) similar to alpha-tubulin I isoform 1;>sp|Q13748|TBA 0.997265 25.6224 0.997265 25.6224 1.99861E-16 151.75 0.961994 15.3848 1.27793E-06 105.35 0.733303 7.32327 0.887594 24.811 0.989262 19.8707 0.0122854 66.38 1 S IGGGDDSFNTFFS PLK1 0.033462 1.99861E-16 151.75 _TIGGGDDpSFNTFFSETGAGK_ TIGGGDDS(0.997)FNT(0.003)FFSETGAGK T(-57.69)IGGGDDS(25.62)FNT(-25.62)FFS(-65.1)ET(-99.47)GAGK 8 2 1044.4333 0.047633 2194000 0.25353 549240 0 0 1532700 0 65089 46916 + 944 734 287 287 2076 2352 19058 11596 Mix4_TiO2_Reinj_1_4 7795 19058 11596 Mix4_TiO2_Reinj_1_4 7795 P68400 P68400 P68400 >sp|P68400|CSK21_HUMAN Casein kinase II subunit alpha OS=Homo sapiens GN=CSNK2A1 PE=1 SV=1 1 83.1523 0 0 1 83.1523 7.30442E-07 110.84 1 S WERFVHSENQHLV 7.30442E-07 110.84 _FVHpSENQHLVSPEALDFLDK_ FVHS(1)ENQHLVSPEALDFLDK FVHS(83.15)ENQHLVS(-83.15)PEALDFLDK 4 3 802.37729 -0.095739 392500 0.33798 0 0 0 392500 0 0 0 945 736 891 891 3003 3417 28727 17892 Mix4_TiO2_Reinj_1_5 1681 28726 17891 Mix4_TiO2_Reinj_1_5 1516 P78332 P78332 P78332 >sp|P78332|RBM6_HUMAN RNA-binding protein 6 OS=Homo sapiens GN=RBM6 PE=1 SV=5 1 5.75535 1 35.2018 0.149884 35.202 1 5.75535 0.0464759 48.17 0 0 1 S TVKKEESPPPPKV CHK1;PKD;Proline-directed 0.020748 0.0464759 48.17 _KEEpSPPPPK_ KEES(1)PPPPK KEES(5.76)PPPPK 4 2 544.75482 -1.0748 97888 5824.1 0 0 92064 0 0 0 946 737 251 251 3160 3587 29982 18639 Mix4_TiO2_Reinj_1_6 2704 29982 18639 Mix4_TiO2_Reinj_1_6 2704 P78346 P78346 P78346 >sp|P78346|RPP30_HUMAN Ribonuclease P protein subunit p30 OS=Homo sapiens GN=RPP30 PE=1 SV=1 1 112.457 0 0 1 112.457 4.03282E-06 112.46 1 S VKKPRPSEGDEDC CK2;PKA 0.042 4.03282E-06 112.46 _KPRPpSEGDEDCLPASK_ KPRPS(1)EGDEDCLPASK KPRPS(112.46)EGDEDCLPAS(-112.46)K 5 3 622.60816 -0.015959 149650 0 0 0 149650 0 0 0 947 741 505 505 6290 7186;7187 62934 38330 Mix4_TiO2_1_5 3138 62934 38330 Mix4_TiO2_1_5 3138 P78362-2;P78362 P78362-2 P78362-2 >sp|P78362-2|SRPK2_HUMAN Isoform 2 of Serine/threonine-protein kinase SRPK2 OS=Homo sapiens GN=SRPK2;>sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2 OS=Homo sapiens GN=SRPK2 PE=1 SV=3 0.999839 38.6499 0.999839 38.6499 0.00619088 80.698 0.00653689 -20.4676 0.206731 31.116 6.4182E-07 -61.1427 0.00395855 88.708 4.73651E-06 -52.4687 0.00143801 97.754 2 S DRSRTVSASSTGD CAMK2;CK1;PKA/AKT 0.00111111 0.00619088 80.698 _TVpSASSpTGDLPK_ TVS(1)ASS(0.117)T(0.883)GDLPK T(-38.65)VS(38.65)AS(-34.8)S(-8.79)T(8.79)GDLPK 3 2 661.76747 0.10754 72670 72670 0 0 0 0 0 0 948 741 508 508 6290 7186;7187 62927 38327 Mix4_InSol_Tio2_Reinj_1 3994 62927 38327 Mix4_InSol_Tio2_Reinj_1 3994 P78362-2;P78362 P78362-2 P78362-2 >sp|P78362-2|SRPK2_HUMAN Isoform 2 of Serine/threonine-protein kinase SRPK2 OS=Homo sapiens GN=SRPK2;>sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2 OS=Homo sapiens GN=SRPK2 PE=1 SV=3 0.836242 7.11259 0.116586 -8.7942 0.00619088 80.698 0.728005 7.40091 0.206731 31.116 0.834991 7.07582 0.00395855 88.708 0.836242 7.11259 0.00143801 97.754 1 S RTVSASSTGDLPK CK1;CK2 0.081 0.00143801 97.754 _TVSASpSTGDLPK_ TVSAS(0.001)S(0.836)T(0.163)GDLPK T(-87.96)VS(-52.47)AS(-28.54)S(7.11)T(-7.11)GDLPK 6 2 621.78431 0.060569 242140 0 0 0 178970 0 43085 20084 949 743 4026 4026 2247;3036 2543;3452 28960 18022 Mix4_TiO2_1_1 5564 20746 12723 Mix4_TiO2_1_1 5987 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 1 14.0167 1 14.0167 3.07575E-05 126.7 0 0 1 117.722 6.16715E-05 117.72 1 77.1577 0.00591036 77.158 0 0 1 S MLKKGGSWIQEIN CHK1;PKD 0.020748 3.07575E-05 126.7 _KGGpSWIQEINVAEK_ KGGS(1)WIQEINVAEK KGGS(14.02)WIQEINVAEK 4 3 546.93442 -0.47643 790100 1.8332 287080 0 0 448860 0 54166 0 950 743 3205 3205 3772 4258;4260 35784 22158 Mix4_TiO2_1_1 4391 35784 22158 Mix4_TiO2_1_1 4391 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 1 94.6365 1 94.6365 6.40168E-39 206.34 0 0 1 88.4921 5.9513E-24 168.32 0 0 0 0 0 0 1 S PLPEDNSMNVDQD PLK1 0.033462 6.40168E-39 206.34 _LTPLPEDNpSMNVDQDGDPSDR_ LTPLPEDNS(1)MNVDQDGDPSDR LT(-94.64)PLPEDNS(94.64)MNVDQDGDPS(-188.11)DR 9 2 1197.9914 -0.49284 3737700 0.032212 631020 0 0 3106700 0 0 0 951 743 1065 1065 3808 4303 36192 22371 Mix4_TiO2_Reinj_1_1 6665 36192 22371 Mix4_TiO2_Reinj_1_1 6665 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 1 67.1349 0.999381 32.0827 0.194807 32.083 1 67.1349 0.0034422 90.562 1 S LFKRLYSLALHPN CAMK2;PKA 0.003024 0.0034422 90.562 _LYpSLALHPNAFK_ LYS(1)LALHPNAFK LY(-67.13)S(67.13)LALHPNAFK 3 2 727.3656 -0.24375 86854 15680 0 0 71174 0 0 0 952 743 841 841 4166 4745 39742 24527 Mix4_TiO2_Reinj_1_1 6364 39742 24527 Mix4_TiO2_Reinj_1_1 6364 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.86727 8.15192 0 0 0 0 0.86727 8.15192 0.0231964 60.81 1 S KKTKNLSSNEAIS CK1;CK2 0.117 0.0231964 60.81 _NLpSSNEAISLEEIR_ NLS(0.867)S(0.133)NEAISLEEIR NLS(8.15)S(-8.15)NEAIS(-55.12)LEEIR 3 2 827.88782 0.1947 78785 0.053611 0 0 0 78785 0 0 0 953 743 1790 1790 4887 5558 46951 28732 Mix4_TiO2_Reinj_1_1 8563 46952 28733 Mix4_TiO2_Reinj_1_2 7604 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.99847 28.1805 0.499988 0 0.104412 49.937 0 0 0.99847 28.1805 0.00376225 76.922 1 S RIARRGSCVTQVG AURORA;AURORA-A;CAMK2;CHK1;PKA;PKD 0.004788 0.00376225 76.922 _RGpSCVTQVGLLESVYEM(ox)FR_ RGS(0.998)CVT(0.002)QVGLLESVYEMFR RGS(28.18)CVT(-28.18)QVGLLES(-52.39)VY(-52.39)EMFR 3 2 1164.0316 -0.12135 294720 69640 0 0 225080 0 0 0 954 743 893 893 4941 5617 47515 29005 Mix4_TiO2_Reinj_1_5 7391 47511 28998 Mix4_TiO2_1_1 6158 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 1 38.0599 1 1.16798 0.00702156 63.617 0 0 1 38.0599 0.0319322 52.775 0 0 0 0 1 S DREKRLSFAVPFR AURORA;AURORA-A;PKA 0.006142092 0.00702156 63.617 _RLpSFAVPFR_ RLS(1)FAVPFR RLS(38.06)FAVPFR 3 2 586.80244 -0.46997 1932800 330360 0 0 1602500 0 0 0 955 743 2672 2672 5704 6498 55924 34231 Mix4_TiO2_1_1 7276 55927 34236 Mix4_TiO2_Reinj_1_1 8098 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.782107 7.22055 0.782107 7.22055 3.06203E-13 134.83 0.122301 -6.048 0.0718279 59.668 0.332449 0 1.25411E-48 214.01 0 0 0 0 1 S PLVDHTSPSSDSL Proline-directed 0.05 1.25411E-48 214.01 _SSFDWLTGSSTDPLVDHTpSPSSDSLLFAHK_ SSFDWLTGSSTDPLVDHT(0.148)S(0.782)PS(0.018)S(0.023)DS(0.029)LLFAHK S(-106.86)S(-106.55)FDWLT(-70.03)GS(-54.58)S(-50.77)T(-50.77)DPLVDHT(-7.22)S(7.22)PS(-16.38)S(-15.36)DS(-14.34)LLFAHK 19 3 1105.5012 0.24054 1765700 2.0161 1765700 0 0 0 0 0 0 956 743 2675 2675 5704 6498 55933 34242 Mix4_TiO2_Reinj_1_5 8455 55927 34236 Mix4_TiO2_Reinj_1_1 8098 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.879771 12.7343 0.414698 0 3.06203E-13 134.83 0.139349 -5.48128 0.0718279 59.668 0.879771 12.7343 1.25411E-48 214.01 0 0 0 0 1 S DHTSPSSDSLLFA CK1 0.081 1.25411E-48 214.01 _SSFDWLTGSSTDPLVDHTSPSpSDSLLFAHK_ SSFDWLTGSSTDPLVDHT(0.002)S(0.039)PS(0.032)S(0.88)DS(0.047)LLFAHK S(-84.73)S(-84.56)FDWLT(-68.94)GS(-57.57)S(-57.57)T(-51.31)DPLVDHT(-25.56)S(-13.56)PS(-14.37)S(12.73)DS(-12.73)LLFAHK 22 4 829.37768 0.12983 264600 0.30213 0 0 0 264600 0 0 0 957 743 2677 2677 5704 6498 55930 34239 Mix4_TiO2_Reinj_1_2 7352 55927 34236 Mix4_TiO2_Reinj_1_1 8098 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.648969 6.14399 0.414698 0 3.06203E-13 134.83 0.4923 5.48128 0.0718279 59.668 0.648969 6.14399 1.25411E-48 214.01 0 0 0 0 1 S TSPSSDSLLFAHK CK1 0.081 1.25411E-48 214.01 _SSFDWLTGSSTDPLVDHTSPSSDpSLLFAHK_ SSFDWLTGSSTDPLVDHT(0.041)S(0.138)PS(0.015)S(0.158)DS(0.649)LLFAHK S(-53.95)S(-53.95)FDWLT(-49.41)GS(-44.49)S(-39.34)T(-36.51)DPLVDHT(-12.03)S(-6.73)PS(-16.5)S(-6.14)DS(6.14)LLFAHK 24 4 829.37768 -0.12131 97098 0.11087 0 0 0 97098 0 0 0 958 743 2612 2612 5809 6622;6625 57266 34898 Mix4_TiO2_1_1 5514 57281 34903 Mix4_TiO2_Reinj_1_1 7037 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.973915 15.9193 0.973915 15.9193 0.000545608 79.95 0.968895 15.7598 6.21185E-07 105.84 0 0 1 S FVETQASQGTLQT 6.21185E-07 105.84 _STVLTPM(ox)FVETQApSQGTLQTR_ STVLTPMFVET(0.001)QAS(0.974)QGT(0.025)LQTR S(-79.95)T(-79.95)VLT(-61.19)PMFVET(-29.33)QAS(15.92)QGT(-15.92)LQT(-45.88)R 14 3 797.71357 0.3701 274450 0.39199 72242 0 0 202210 0 0 0 959 743 2827 2827 6086 6941 60135 36425 Mix4_TiO2_Reinj_1_1 2655 60135 36425 Mix4_TiO2_Reinj_1_1 2655 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.989175 19.6708 0 0 0.989175 19.6708 0.109544 38.073 0 0 0 0 1 S DKFKTLSEKNNIT 0.109544 38.073 _TLpSEKNNITQK_ T(0.011)LS(0.989)EKNNITQK T(-19.67)LS(19.67)EKNNIT(-38.07)QK 3 2 678.33196 -0.015734 38028 0 0 0 38028 0 0 0 960 743 2624 2624 6173 7050 61197 37079 Mix4_TiO2_Reinj_1_1 2071 61197 37079 Mix4_TiO2_Reinj_1_1 2071 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.987197 18.8753 0.987197 18.8753 0.0445107 48.792 0 0 0 0 1 S TRTQEGSLSARWP CK1;PLK1 0.033462 0.0445107 48.792 _TQEGpSLSAR_ TQEGS(0.987)LS(0.013)AR T(-48.79)QEGS(18.88)LS(-18.88)AR 5 2 514.72405 -0.015594 58340 0.18608 0 0 0 58340 0 0 0 961 744 709 709 3662 4128 34418 21400 Mix4_TiO2_1_5 6747 34418 21400 Mix4_TiO2_1_5 6747 P80192-4;P80192 P80192-4 P80192-4 >sp|P80192-4|M3K9_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens GN=MAP3K9;>sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens GN=MAP3K9 PE=1 SV=3 0.624415 2.403 0.624415 2.403 0.0102884 72.954 0 0 1 S RLQHSPSQSYLCI 0.0102884 72.954 _LQHSPpSQSYLCIPFPR_ LQHS(0.359)PS(0.624)QS(0.016)YLCIPFPR LQHS(-2.4)PS(2.4)QS(-15.85)Y(-33.34)LCIPFPR 6 3 670.64829 -0.33978 26783 26783 0 0 0 0 0 0 962 746 399 399 5126 5831 49595 30289 Mix4_TiO2_Reinj_1_5 7374 49595 30289 Mix4_TiO2_Reinj_1_5 7374 P82094-2;P82094 P82094-2 P82094-2 >sp|P82094-2|TMF1_HUMAN Isoform 2 of TATA element modulatory factor OS=Homo sapiens GN=TMF1;>sp|P82094|TMF1_HUMAN TATA element modulatory factor OS=Homo sapiens GN=TMF1 PE=1 SV=2 0.5 0 0 0 0.5 0 1.57995E-07 103.69 1 S MEESGRSATPVNC CK1 0.081 1.57995E-07 103.69 _pSATPVNCEQPDILVSSTPINEGQTVLDK_ S(0.5)AT(0.5)PVNCEQPDILVSSTPINEGQTVLDK S(0)AT(0)PVNCEQPDILVS(-80.51)S(-89.45)T(-89.45)PINEGQT(-103.69)VLDK 1 3 1031.488 0.60031 369090 0 0 0 369090 0 0 0 963 749 504 504 6752 7726 68504 42048 Mix4_InSol_TiO2_2 2297 68503 42047 Mix4_InSol_TiO2_1 3231 P83436 P83436 P83436 >sp|P83436|COG7_HUMAN Conserved oligomeric Golgi complex subunit 7 OS=Homo sapiens GN=COG7 PE=1 SV=1 0.964942 14.4277 0.109708 -9.09286 0.0386994 50.632 0.692582 3.60123 0.303114 24.272 0.964942 14.4277 0.00450573 69.905 0.236835 -0.871939 0.00533387 67.835 1 S GKYLSDSCSPRSL NEK6 0.076 0.00450573 69.905 _YLSDpSCSPR_ YLSDS(0.965)CS(0.035)PR Y(-43.59)LS(-36.76)DS(14.43)CS(-14.43)PR 5 2 582.7232 -0.1396 417550 0 0 0 400100 0 17444 0 964 749 506 506 6752 7726 68505 42049 Mix4_InSol_Tio2_Reinj_1 3234 68503 42047 Mix4_InSol_TiO2_1 3231 P83436 P83436 P83436 >sp|P83436|COG7_HUMAN Conserved oligomeric Golgi complex subunit 7 OS=Homo sapiens GN=COG7 PE=1 SV=1 0.996396 24.4169 0.890276 9.09286 0.0386994 50.632 0.302237 -3.60123 0.303114 24.272 0.994997 22.9869 0.00450573 69.905 0.996396 24.4169 0.00533387 67.835 1 S YLSDSCSPRSLAG CDK1;CK1;Proline-directed 0.0057 0.00450573 69.905 _YLSDSCpSPR_ YLSDS(0.004)CS(0.996)PR Y(-67.84)LS(-67.84)DS(-24.42)CS(24.42)PR 7 2 582.7232 -0.082656 284280 105750 0 0 0 0 120090 58441 965 751 189 189 6089 6946 60170 36447 Mix4_TiO2_Reinj_1_6 1850 60170 36447 Mix4_TiO2_Reinj_1_6 1850 P84098 P84098 P84098 >sp|P84098|RL19_HUMAN 60S ribosomal protein L19 OS=Homo sapiens GN=RPL19 PE=1 SV=1 0.998584 28.8617 0.998584 28.8617 0.0751266 40.133 1 S EIIKTLSKEEETK CHK1;CK2;PKD 0.020748 0.0751266 40.133 _TLpSKEEETKK_ T(0.001)LS(0.999)KEEETKK T(-28.86)LS(28.86)KEEET(-39.29)KK 3 3 424.87428 -0.16784 14452 0.17686 0 0 0 14452 0 0 0 966 752 723 723 3308 3744 31209 19332 Mix4_TiO2_Reinj_1_5 3188 31209 19332 Mix4_TiO2_Reinj_1_5 3188 P98175;P98175-2;P98175-3;P98175-4 P98175 P98175 >sp|P98175|RBM10_HUMAN RNA-binding protein 10 OS=Homo sapiens GN=RBM10 PE=1 SV=3;>sp|P98175-2|RBM10_HUMAN Isoform 2 of RNA-binding protein 10 OS=Homo sapiens GN=RBM10;>sp|P98175-3|RBM10_HUMAN Isoform 3 of RNA-binding protein 10 OS=Homo sapiens GN=RBM10;>sp 0.999968 44.9262 0.999017 30.0716 0.20303 30.072 0.93813 11.8078 0.487685 12.906 0.999968 44.9262 0.0625068 44.926 0 0 0 0 1 S ASDDRPSPPRGLV CDK1;CDK2;PKA;Proline-directed 0.0057 0.0625068 44.926 _LASDDRPpSPPR_ LASDDRPS(1)PPR LAS(-44.93)DDRPS(44.93)PPR 8 2 645.79554 -0.010948 219060 37255 19054 0 162750 0 0 0 967 757 110 110 3075;3076 3496;3497 29292 18277 Mix4_InSol_Tio2_Reinj_1 3391 29294 18280 Mix4_TiO2_1_4 2509 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.999378 32.0612 0.997898 26.7639 0.00127469 86.624 0.942849 12.1742 0.0312412 52.994 0.5 0 0.684381 4.9807 0.999378 32.0612 0.00127469 86.624 1 S HPPRKISTEDINK CAMK2;CK2;PKA 0.004788 0.00127469 86.624 _KIpSTEDINK_ KIS(0.999)T(0.001)EDINK KIS(32.06)T(-32.06)EDINK 3 2 564.27084 0.40577 2182400 365160 0 0 1197900 0 172080 447250 968 757 138 138 3768 4253 35655 22042 Mix4_TiO2_Reinj_1_3 7288 35648 22033 Mix4_TiO2_1_3 6553 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.999982 47.7528 0.999964 44.4362 1.59809E-05 116.86 0.972322 18.467 0.0225677 61.382 0.999982 47.7528 0.00155916 90.743 0.997719 29.4196 0.335659 29.42 0.889012 9.03647 0.0525665 53.397 1 S EKLTLNSPIFDKP Proline-directed 0.05 1.59809E-05 116.86 _LTLNpSPIFDKPLSR_ LTLNS(1)PIFDKPLSR LT(-47.75)LNS(47.75)PIFDKPLS(-57.77)R 5 3 560.9622 -0.43884 8765900 2413300 38193 0 5251000 0 633990 429390 969 757 86 86 3861;3862 4373;4374;4375 36603 22572 Mix4_InSol_TiO2_2 3345 36594 22570 Mix4_TiO2_Reinj_1_3 3291 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.23603 0.18236 8.46573E-09 -80.7234 0.000380325 87.454 2.26974E-08 -76.4402 6.91417E-40 207.78 0.23603 0.18236 2.09186 4.4626 0.000207151 -36.8352 0.000307889 85.822 1 S GESDQASATSSDE CK1;GSK3 0.081 6.91417E-40 207.78 _MGSDGESDQApSATSSDEVQSPVRVR_ MGS(0.084)DGES(0.084)DQAS(0.236)AT(0.226)S(0.084)S(0.084)DEVQS(0.2)PVRVR MGS(-4.46)DGES(-4.46)DQAS(0.18)AT(-0.18)S(-4.46)S(-4.46)DEVQS(-0.72)PVRVR 11 3 892.37987 0.35169 0 0 0 0 0 0 0 0 970 757 95 95 3861;3862 4373;4374;4375 36594 22570 Mix4_TiO2_Reinj_1_3 3291 36594 22570 Mix4_TiO2_Reinj_1_3 3291 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 1 90.4142 0.999999 63.6998 0.000380325 87.454 1 90.4142 6.91417E-40 207.78 0.199765 -0.724473 2.09186 4.4626 0.999551 36.8352 0.000307889 85.822 1 S SSDEVQSPVRVRM CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 6.91417E-40 207.78 _M(ox)GSDGESDQASATSSDEVQpSPVR_ MGSDGESDQASATSSDEVQS(1)PVR MGS(-203.54)DGES(-198.48)DQAS(-144.83)AT(-117.31)S(-112.29)S(-90.41)DEVQS(90.41)PVR 20 2 1218.4789 0.68347 328740 49068 0 0 212180 0 0 67496 971 757 119 119 4945;4946 5621;5622 47563 29042 Mix4_TiO2_Reinj_1_6 5134 47552 29023 Mix4_TiO2_1_3 5332 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 1 9.12704 1 8.17407 0.00126028 86.458 1 55.4384 0.0235221 55.438 1 9.12704 0.00864154 60.15 0 0 1 20.4439 0.376137 20.444 1 32.0539 0.194015 32.054 1 S DINKRLSLPADIR AURORA;AURORA-1;AURORA-A;CHK1;PKA;PKD 0.006142092 0.00126028 86.458 _RLpSLPADIR_ RLS(1)LPADIR RLS(9.13)LPADIR 3 2 560.79736 -0.72348 29115000 7049600 219890 0 21136000 0 501530 208110 972 757 153 153 5068;6601 5762;7556 66995 41122 Mix4_TiO2_Reinj_1_4 7138 49005 29944 Mix4_TiO2_Reinj_1_3 6774 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.999546 33.4304 0.999528 33.2598 0.0014418 99.976 0.960439 13.852 0.0924439 39.536 0.999546 33.4304 0.00316303 116.23 0.997196 25.51 0.00134669 98.476 0.999223 31.0921 0.00716146 69.403 1 S RRLRRVSLSEIGF AURORA;AURORA-1;AURORA-A;CAMK2;CK2;PKA;PKA/AKT 0.00111111 0.00316303 116.23 _VpSLSEIGFGK_ VS(1)LSEIGFGK VS(33.43)LS(-33.43)EIGFGK 2 2 558.77047 -0.028487 6519800 4489100 53719 0 979470 0 571930 425520 973 757 155 155 5068;6601 5762;7556 49005 29944 Mix4_TiO2_Reinj_1_3 6774 49005 29944 Mix4_TiO2_Reinj_1_3 6774 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.975362 15.9757 0.183765 -6.47554 0.0014418 99.976 0.0395612 -13.852 0.0924439 39.536 0.975362 15.9757 0.00316303 116.23 0.002804 -25.51 0.00134669 98.476 0.32192 -3.23532 0.00716146 69.403 1 S LRRVSLSEIGFGK 0.00316303 116.23 _RVSLpSEIGFGK_ RVS(0.025)LS(0.975)EIGFGK RVS(-15.98)LS(15.98)EIGFGK 5 2 636.82103 -0.26365 12144000 0 0 0 12144000 0 0 0 974 758 180 180 509;4816 575;5466 4727 2856 Mix4_TiO2_1_3 5515 45981 28135 Mix4_TiO2_Reinj_1_4 5850 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 0.999941 42.2596 0.999941 42.2596 0.00173629 94.139 0.998271 27.6141 0.107899 38.213 0.999894 39.7388 0.00134794 98.462 0 0 0.996652 24.7378 0.00221973 88.757 0.999485 32.8763 0.00186812 92.672 1 S RRSRRASLSEIGF AURORA;AURORA-1;AURORA-A;CAMK2;CK1;CK2;PKA;PKA/AKT 0.00111111 0.00134794 98.462 _ApSLSEIGFGK_ AS(1)LSEIGFGK AS(42.26)LS(-42.26)EIGFGK 2 2 544.75482 0.27638 31588000 6907400 111360 0 18584000 0 5808600 176430 975 758 182 182 509;4816 575;5466 45964 28110 Mix4_InSol_Tio2_Reinj_1 6291 45981 28135 Mix4_TiO2_Reinj_1_4 5850 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 0.711203 3.914 0.30684 -3.53921 0.00173629 94.139 0.00172918 -27.6141 0.107899 38.213 0.16691 -6.98209 0.00134794 98.462 0 0 0.204851 -5.89009 0.00221973 88.757 0.711203 3.914 0.00186812 92.672 1 S SRRASLSEIGFGK 0.00134794 98.462 _RASLpSEIGFGK_ RAS(0.289)LS(0.711)EIGFGK RAS(-3.91)LS(3.91)EIGFGK 5 2 622.80538 0.24052 1513700 0 0 0 0 0 0 1513700 976 758 165 165 3663 4129;4130 34448 21411 Mix4_InSol_Tio2_Reinj_1 7036 34423 21406 Mix4_TiO2_Reinj_1_4 5962 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 1 113.111 1 82.1967 0.000308792 98.293 0.99985 38.2435 0.159028 38.244 1 118.634 2.9741E-11 158.39 0 0 1 143.82 6.9445E-09 145.47 1 113.111 9.5642E-07 127.43 1 S EKLQINSPPFDQP Proline-directed 0.05 2.9741E-11 158.39 _LQINpSPPFDQPMSR_ LQINS(1)PPFDQPMSR LQINS(113.11)PPFDQPMS(-113.11)R 5 2 855.38948 0.20871 1207300 109350 24966 0 324190 0 463630 285220 977 758 116 116 3863 4376;4377 36613 22578 Mix4_InSol_Tio2_Reinj_2 3690 36628 22580 Mix4_InSol_TiO2_1 5285 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 0.570359 5.5172 0 0 0 0 7.1694E-13 -121.425 8.24814E-26 162.2 0.00724096 -21.1749 8.07194E-47 208.68 0.570359 5.5172 3.57476E-12 129.1 1 S DQASGTSSDEVQS CK1;CK2 0.081 8.07194E-47 208.68 _M(ox)GSDGESDQASGTpSSDEVQSPTGVCLR_ MGS(0.019)DGES(0.019)DQAS(0.019)GT(0.019)S(0.57)S(0.16)DEVQS(0.147)PT(0.049)GVCLR MGS(-14.88)DGES(-14.88)DQAS(-14.88)GT(-14.88)S(5.52)S(-5.52)DEVQS(-5.9)PT(-10.69)GVCLR 14 3 951.71107 -0.11968 17674 0.015236 0 0 0 0 0 0 17674 978 758 117 117 3863 4376;4377 36612 22577 Mix4_InSol_Tio2_Reinj_1 5004 36628 22580 Mix4_InSol_TiO2_1 5285 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 0.47267 1.19301 0 0 0 0 2.66133E-10 -95.7287 8.24814E-26 162.2 0.00500727 -22.7769 8.07194E-47 208.68 0.47267 1.19301 3.57476E-12 129.1 1 S QASGTSSDEVQSP CK1 0.143 8.07194E-47 208.68 _M(ox)GSDGESDQASGTSpSDEVQSPTGVCLR_ MGSDGESDQASGT(0.028)S(0.359)S(0.473)DEVQS(0.113)PT(0.026)GVCLR MGS(-32.51)DGES(-30.43)DQAS(-30.81)GT(-12.33)S(-1.19)S(1.19)DEVQS(-6.2)PT(-12.57)GVCLR 15 2 1427.063 0.051558 0 0 0 0 0 0 0 0 0 979 758 122 122 3863 4376;4377 36628 22580 Mix4_InSol_TiO2_1 5285 36628 22580 Mix4_InSol_TiO2_1 5285 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 0.996357 24.3693 0 0 0 0 0.995335 23.2916 8.24814E-26 162.2 0.996357 24.3693 8.07194E-47 208.68 0.987158 18.8816 3.57476E-12 129.1 1 S SSDEVQSPTGVCL ERK/MAPK;Proline-directed 0.0034 8.07194E-47 208.68 _MGSDGESDQASGTSSDEVQpSPTGVCLR_ MGSDGESDQASGTSSDEVQS(0.996)PT(0.004)GVCLR MGS(-189.37)DGES(-170.07)DQAS(-147.32)GT(-123.13)S(-131.46)S(-118.49)DEVQS(24.37)PT(-24.37)GVCLR 20 3 946.37943 0.084716 5978000 5.1535 0 0 0 1063800 0 2624600 2289600 980 758 137 137 4917;4918 5590;5591;5592 47210 28841 Mix4_TiO2_Reinj_1_4 4409 47181 28832 Mix4_InSol_TiO2_1 5043 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 1 32.9593 1 29.9419 0.223622 29.942 0 0 1 32.9593 0.161704 32.959 0 0 1 65.049 0.00139505 88.016 1 23.519 0.00104984 84.024 1 S RIHRRISMEDLNK AURORA;AURORA-A;CAMK2;CHK1;CK2;PKA;PKD 0.004788 0.00139505 88.016 _RIpSMEDLNKR_ RIS(1)MEDLNKR RIS(32.96)MEDLNKR 3 2 671.32087 0.15371 3370200 78381 0 0 1250900 0 1067100 973820 981 758 146 146 4945 5621 47563 29042 Mix4_TiO2_Reinj_1_6 5134 47552 29023 Mix4_TiO2_1_3 5332 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 1 9.12704 1 8.17407 0.00126028 86.458 1 55.4384 0.0235221 55.438 1 9.12704 0.00864154 60.15 0 0 1 20.4439 0.376137 20.444 1 32.0539 0.194015 32.054 1 S DLNKRLSLPADIR AURORA;AURORA-1;AURORA-A;CHK1;PKA;PKD 0.006142092 0.00126028 86.458 _RLpSLPADIR_ RLS(1)LPADIR RLS(9.13)LPADIR 3 2 560.79736 -0.72348 28043000 7003000 219890 0 20384000 0 227170 208110 982 758 9 9 4949 5625 47593 29057 Mix4_TiO2_Reinj_1_3 5747 47594 29060 Mix4_TiO2_Reinj_1_4 5759 Q00537 Q00537 Q00537 >sp|Q00537|CDK17_HUMAN Cell division protein kinase 17 OS=Homo sapiens GN=CDK17 PE=1 SV=2 0.999916 40.7837 0.99973 35.6777 0.00591548 112.76 0.999916 40.7837 6.50343E-05 128.41 0.906048 9.84245 0.295733 27.726 1 S KFKRRLSLTLRGS AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.00111111 6.50343E-05 128.41 _RLpSLTLR_ RLS(1)LTLR RLS(40.78)LT(-40.78)LR 3 2 469.76278 -0.3142 14863000 48.781 2115200 0 0 10551000 0 2196900 0 983 759 350 350 549 626 5180 3162 Mix4_TiO2_1_4 6886 5180 3162 Mix4_TiO2_1_4 6886 Q00587;Q00587-2 Q00587 Q00587 >sp|Q00587|BORG5_HUMAN Cdc42 effector protein 1 OS=Homo sapiens GN=CDC42EP1 PE=1 SV=1;>sp|Q00587-2|BORG5_HUMAN Isoform 2 of Cdc42 effector protein 1 OS=Homo sapiens GN=CDC42EP1 1 75.2424 1 75.2424 0.00207562 90.386 0 0 1 S LPQARASWESLDE PKA 0.042 0.00207562 90.386 _ApSWESLDEEWR_ AS(1)WESLDEEWR AS(75.24)WES(-75.24)LDEEWR 2 2 744.29557 0.39305 28053 28053 0 0 0 0 0 0 984 759 121 121 3937 4484 37349 22962 Mix4_TiO2_Reinj_1_4 8464 37349 22962 Mix4_TiO2_Reinj_1_4 8464 Q00587;Q00587-2 Q00587 Q00587 >sp|Q00587|BORG5_HUMAN Cdc42 effector protein 1 OS=Homo sapiens GN=CDC42EP1 PE=1 SV=1;>sp|Q00587-2|BORG5_HUMAN Isoform 2 of Cdc42 effector protein 1 OS=Homo sapiens GN=CDC42EP1 1 103.159 1 68.3509 0.00037336 88.589 1 103.159 3.63953E-22 171.17 1 S IIKNAISLPQLNQ 3.63953E-22 171.17 _NAIpSLPQLNQAAYDSLVVGK_ NAIS(1)LPQLNQAAYDSLVVGK NAIS(103.16)LPQLNQAAY(-103.16)DS(-121.82)LVVGK 4 3 727.70323 -0.17732 631280 177320 0 0 453960 0 0 0 985 759 192 192 5039;5185 5731;5903 48737 29798 Mix4_TiO2_Reinj_1_4 6068 48736 29797 Mix4_TiO2_1_4 5340 Q00587;Q00587-2 Q00587 Q00587 >sp|Q00587|BORG5_HUMAN Cdc42 effector protein 1 OS=Homo sapiens GN=CDC42EP1 PE=1 SV=1;>sp|Q00587-2|BORG5_HUMAN Isoform 2 of Cdc42 effector protein 1 OS=Homo sapiens GN=CDC42EP1 0.999272 31.8917 0.993246 21.6923 0.00350328 72.412 0 0 0.999272 31.8917 0.00468255 69.464 0 0 0 0 1 S GLRRSDSLLSFRL CAMK2;CHK1;CHK1/2;PKD 0.003192 0.00350328 72.412 _RSDpSLLSFR_ RSDS(0.999)LLS(0.001)FR RS(-40.89)DS(31.89)LLS(-31.89)FR 4 2 580.77662 -0.20666 1027100 217140 0 0 809950 0 0 0 986 762 252 252 306 349 2857 1750 Mix4_TiO2_Reinj_1_5 7604 2857 1750 Mix4_TiO2_Reinj_1_5 7604 Q00839-2;Q00839 Q00839-2 Q00839-2 >sp|Q00839-2|HNRPU_HUMAN Isoform Short of Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU;>sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU PE=1 SV=6 0.999992 51.0259 0.56221 1.72289 1.18765 39.65 0 0 0.999992 51.0259 2.23083E-08 115.29 0 0 0.999926 41.358 0.000256803 86.554 0.969918 15.0848 0.000256802 86.554 1 S KYSRAKSPQPPVE CAMK2;CK1;Proline-directed 0.042 2.23083E-08 115.29 _AKpSPQPPVEEEDEHFDDTVVCLDTYNCDLHFK_ AKS(1)PQPPVEEEDEHFDDTVVCLDTYNCDLHFK AKS(51.03)PQPPVEEEDEHFDDT(-51.03)VVCLDT(-94.88)Y(-96.03)NCDLHFK 3 4 979.41949 -0.29718 27002000 62209 0 0 25854000 0 684140 401990 987 762 2 2 5750;5751 6553;6554 56541 34527 Mix4_TiO2_1_5 1912 56529 34516 Mix4_InSol_TiO2_1 2933 Q00839-2;Q00839 Q00839-2 Q00839-2 >sp|Q00839-2|HNRPU_HUMAN Isoform Short of Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU;>sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU PE=1 SV=6 0.867186 8.48577 0.867186 8.48577 0.0887753 51.17 0 0 0.790239 8.03049 0.377436 27.757 0 0 0.481535 0 0.00315754 95.077 0.433778 1.85312 0.0213137 60.869 1 S _____MSSSPVNV 0.00315754 95.077 _(ac)pSSSPVNVKK_ S(0.867)S(0.123)S(0.01)PVNVKK S(8.49)S(-8.49)S(-19.42)PVNVKK 1 2 534.26027 -0.27981 4213500 812790 0 0 3400800 0 0 0 988 762 3 3 5750;5751 6553;6554 56531 34519 Mix4_TiO2_1_5 2315 56529 34516 Mix4_InSol_TiO2_1 2933 Q00839-2;Q00839 Q00839-2 Q00839-2 >sp|Q00839-2|HNRPU_HUMAN Isoform Short of Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU;>sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU PE=1 SV=6 0.619472 2.55338 0.619472 2.55338 0.0887753 51.17 0 0 0.382867 0 0.377436 27.757 0 0 0.481535 0 0.00315754 95.077 0.283111 -1.85312 0.0213137 60.869 1 S ____MSSSPVNVK 0.00315754 95.077 _(ac)SpSSPVNVK_ S(0.036)S(0.619)S(0.344)PVNVK S(-12.31)S(2.55)S(-2.55)PVNVK 2 2 470.21279 -0.71539 0 0 0 0 0 0 0 0 989 762 4 4 5750;5751 6553;6554 56530 34517 Mix4_InSol_Tio2_Reinj_1 2924 56529 34516 Mix4_InSol_TiO2_1 2933 Q00839-2;Q00839 Q00839-2 Q00839-2 >sp|Q00839-2|HNRPU_HUMAN Isoform Short of Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU;>sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens GN=HNRNPU PE=1 SV=6 0.915707 10.593 0.775467 8.39313 0.0887753 51.17 0 0 0.285921 -1.7536 0.377436 27.757 0 0 0.914059 10.4666 0.00315754 95.077 0.915707 10.593 0.0213137 60.869 1 S ___MSSSPVNVKK Polo box;Proline-directed 0.00405 0.00315754 95.077 _(ac)SSpSPVNVK_ S(0.004)S(0.08)S(0.916)PVNVK S(-23.17)S(-10.59)S(10.59)PVNVK 3 2 470.21279 -0.00421 293430 0 0 0 0 0 132290 161140 990 764 2102 2102 4995 5679 48198 29463 Mix4_TiO2_Reinj_1_1 1642 48198 29463 Mix4_TiO2_Reinj_1_1 1642 Q01082;Q01082-2;Q01082-3 Q01082 Q01082 >sp|Q01082|SPTB2_HUMAN Spectrin beta chain, brain 1 OS=Homo sapiens GN=SPTBN1 PE=1 SV=2;>sp|Q01082-2|SPTB2_HUMAN Isoform Short of Spectrin beta chain, brain 1 OS=Homo sapiens GN=SPTBN1;>sp|Q01082-3|SPTB2_HUMAN Isoform 2 of Spectrin beta chain, brain 1 OS=H 0.999583 36.8041 0.900917 12.5972 0.508021 12.597 0.999583 36.8041 0.0551001 44.313 0 0 0 0 1 S RKRRPPSPEPSTK CAMK2;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.0551001 44.313 _RPPpSPEPSTK_ RPPS(1)PEPSTK RPPS(36.8)PEPS(-36.8)T(-36.8)K 4 2 588.27645 0.14003 275100 17379 0 0 257720 0 0 0 991 765 200 200 1969 2229 18007 10767 Mix4_TiO2_2_4 3480 18009 10769 Mix4_TiO2_Reinj_1_4 4132 Q01085 Q01085 Q01085 >sp|Q01085|TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens GN=TIAL1 PE=1 SV=1 0.956544 13.4266 0.00814121 -20.8576 0.00249178 85.729 0.956544 13.4266 0.16096 33.672 0.5 0 0.00280012 121.54 1 S EDVVNQSSPKNCT 0.00280012 121.54 _FEDVVNQpSSPK_ FEDVVNQS(0.957)S(0.043)PK FEDVVNQS(13.43)S(-13.43)PK 8 2 665.28976 0.51506 41853 0.07495 0 13007 0 28846 0 0 0 992 765 201 201 1969 2229 18006 10765 Mix4_TiO2_1_4 3426 18009 10769 Mix4_TiO2_Reinj_1_4 4132 Q01085 Q01085 Q01085 >sp|Q01085|TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens GN=TIAL1 PE=1 SV=1 0.991859 20.8576 0.991859 20.8576 0.00249178 85.729 0.0434555 -13.4266 0.16096 33.672 0.909308 10.0114 0.00280012 121.54 1 S DVVNQSSPKNCTV CDK1;Polo box;Proline-directed 0.00405 0.00280012 121.54 _FEDVVNQSpSPK_ FEDVVNQS(0.008)S(0.992)PK FEDVVNQS(-20.86)S(20.86)PK 9 2 665.28976 0.34762 719720 1.2889 164070 0 0 555660 0 0 0 993 767 303 303 4580 5200;5201 43311 26556 Mix4_TiO2_1_4 7681 43312 26557 Mix4_TiO2_Reinj_1_4 8236 Q01196-8;Q01196-2;Q01196-10;Q01196-9;Q01196;Q01196-11 Q01196-8 Q01196-8 >sp|Q01196-8|RUNX1_HUMAN Isoform AML-1G of Runt-related transcription factor 1 OS=Homo sapiens GN=RUNX1;>sp|Q01196-2|RUNX1_HUMAN Isoform AML-1A of Runt-related transcription factor 1 OS=Homo sapiens GN=RUNX1;>sp|Q01196-10|RUNX1_HUMAN Isoform AML-1I of Runt 0.874935 10.2872 0.874935 10.2872 0.733705 50.859 0.863702 11.2117 0.041407 73.393 1 S HPATPISPGRASG CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.041407 73.393 _QIQPSPPWSYDQSYQYLGSIASPSVHPATPIpSPGR_ QIQPSPPWSYDQS(0.001)Y(0.001)QY(0.001)LGS(0.002)IAS(0.005)PS(0.033)VHPAT(0.082)PIS(0.875)PGR QIQPS(-41.09)PPWS(-33.85)Y(-33.85)DQS(-30.02)Y(-30.02)QY(-30.63)LGS(-26.65)IAS(-22.73)PS(-14.19)VHPAT(-10.29)PIS(10.29)PGR 32 3 1297.9508 -0.41027 906850 260160 0 0 646690 0 0 0 994 767 48 48 4875 5543;5544 46791 28634 Mix4_TiO2_1_4 4180 46791 28634 Mix4_TiO2_1_4 4180 Q01196-8;Q01196-2;Q01196-10;Q01196-9;Q01196;Q01196-4;Q01196-3;Q01196-7;Q01196-5;Q01196-6 Q01196-8 Q01196-8 >sp|Q01196-8|RUNX1_HUMAN Isoform AML-1G of Runt-related transcription factor 1 OS=Homo sapiens GN=RUNX1;>sp|Q01196-2|RUNX1_HUMAN Isoform AML-1A of Runt-related transcription factor 1 OS=Homo sapiens GN=RUNX1;>sp|Q01196-10|RUNX1_HUMAN Isoform AML-1I of Runt 0.999571 36.2791 0.999571 36.2791 0.00428917 81.587 0.177088 -4.22737 0.911609 4.2274 0.984012 19.1979 0.251106 31.03 0 0 0 0 1 S PPSTALSPGKMSE CDK1;CDK2;CK1;Proline-directed 0.0057 0.00428917 81.587 _RFTPPSTALpSPGK_ RFTPPSTALS(1)PGK RFT(-46.73)PPS(-37.63)T(-36.28)ALS(36.28)PGK 10 2 719.85814 -0.13004 478110 59863 0 0 418250 0 0 0 995 768 308 308 5315 6051 51589 31584 Mix4_InSol_TiO2_1 4283 51592 31587 Mix4_TiO2_Reinj_1_4 3830 Q01518;Q01518-2 Q01518 Q01518 >sp|Q01518|CAP1_HUMAN Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 PE=1 SV=5;>sp|Q01518-2|CAP1_HUMAN Isoform 2 of Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 0.498632 0 0.469793 0 4.52763E-10 127.6 0.498632 0 0.133975 45.099 0.400763 0 1.28929 7.8231 1 S APKPQTSPSPKRA Proline-directed 0.05 4.52763E-10 127.6 _SGPKPFSAPKPQpTSPSPK_ SGPKPFSAPKPQT(0.499)S(0.499)PS(0.003)PK S(-45.1)GPKPFS(-45.1)APKPQT(0)S(0)PS(-22.66)PK 14 3 639.98719 -0.17348 0 0 0 0 0 0 0 0 996 768 310 310 5315 6051 51592 31587 Mix4_TiO2_Reinj_1_4 3830 51592 31587 Mix4_TiO2_Reinj_1_4 3830 Q01518;Q01518-2 Q01518 Q01518 >sp|Q01518|CAP1_HUMAN Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 PE=1 SV=5;>sp|Q01518-2|CAP1_HUMAN Isoform 2 of Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 0.971795 16.3622 0.971795 16.3622 4.52763E-10 127.6 0.00270536 -22.6556 0.133975 45.099 0.0661579 -7.82306 1.28929 7.8231 1 S KPQTSPSPKRATK CDK1;CDK2;Proline-directed 0.0057 4.52763E-10 127.6 _SGPKPFSAPKPQTSPpSPK_ SGPKPFSAPKPQT(0.006)S(0.022)PS(0.972)PK S(-108.4)GPKPFS(-59.23)APKPQT(-22.28)S(-16.36)PS(16.36)PK 16 2 959.47714 0.55624 125830 0 0 0 125830 0 0 0 997 769 31 31 5085 5784 49198 30032 Mix4_TiO2_1_2 2947 49199 30033 Mix4_TiO2_Reinj_1_2 3646 Q01650 Q01650 Q01650 >sp|Q01650|LAT1_HUMAN Large neutral amino acids transporter small subunit 1 OS=Homo sapiens GN=SLC7A5 PE=1 SV=2 0.5 0 0.5 0 2.33516E-06 111.54 0.0087678 -20.5328 6.11477E-22 174.62 0 0 0 0 1 S KMLAAKSADGSAP GSK3 0.081 6.11477E-22 174.62 _pSADGSAPAGEGEGVTLQR_ S(0.5)ADGS(0.5)APAGEGEGVTLQR S(0)ADGS(0)APAGEGEGVT(-111.54)LQR 1 2 891.38872 0.27345 43174 0.055006 43174 0 0 0 0 0 0 998 769 35 35 5085 5784 49199 30033 Mix4_TiO2_Reinj_1_2 3646 49199 30033 Mix4_TiO2_Reinj_1_2 3646 Q01650 Q01650 Q01650 >sp|Q01650|LAT1_HUMAN Large neutral amino acids transporter small subunit 1 OS=Homo sapiens GN=SLC7A5 PE=1 SV=2 0.991232 20.5328 0.5 0 2.33516E-06 111.54 0.991232 20.5328 6.11477E-22 174.62 0 0 0 0 1 S AKSADGSAPAGEG CK1 0.143 6.11477E-22 174.62 _SADGpSAPAGEGEGVTLQR_ S(0.009)ADGS(0.991)APAGEGEGVTLQR S(-20.53)ADGS(20.53)APAGEGEGVT(-147.02)LQR 5 2 891.38872 0.46888 176220 0.22451 43174 0 0 133040 0 0 0 999 770 545 545 4980 5662 48038 29377 Mix4_TiO2_Reinj_1_5 5648 48038 29377 Mix4_TiO2_Reinj_1_5 5648 Q01804;Q01804-3 Q01804 Q01804 >sp|Q01804|OTUD4_HUMAN OTU domain-containing protein 4 OS=Homo sapiens GN=OTUD4 PE=1 SV=3;>sp|Q01804-3|OTUD4_HUMAN Isoform 3 of OTU domain-containing protein 4 OS=Homo sapiens GN=OTUD4 0.734344 7.42928 0.401688 -0.907014 4.52946E-07 109.21 0.734344 7.42928 1.17024E-07 115.81 1 S KYATVSSPSKSKK CDK1;CDK2;ERK/MAPK;GSK3;Polo box;Proline-directed 0.0034 1.17024E-07 115.81 _RPEPSTLENITDDKYATVSpSPSK_ RPEPSTLENITDDKYATVS(0.133)S(0.734)PS(0.133)K RPEPS(-115.81)T(-115.81)LENIT(-92.61)DDKY(-41.96)AT(-36.96)VS(-7.43)S(7.43)PS(-7.43)K 20 3 872.41273 0.90372 1503300 0 0 0 1503300 0 0 0 1000 770 547 547 4980 5662 48037 29376 Mix4_TiO2_1_5 4996 48038 29377 Mix4_TiO2_Reinj_1_5 5648 Q01804;Q01804-3 Q01804 Q01804 >sp|Q01804|OTUD4_HUMAN OTU domain-containing protein 4 OS=Homo sapiens GN=OTUD4 PE=1 SV=3;>sp|Q01804-3|OTUD4_HUMAN Isoform 3 of OTU domain-containing protein 4 OS=Homo sapiens GN=OTUD4 0.494983 0.907014 0.494983 0.907014 4.52946E-07 109.21 0.132731 -7.42928 1.17024E-07 115.81 1 S ATVSSPSKSKKLE CK1 0.081 1.17024E-07 115.81 _RPEPSTLENITDDKYATVSSPpSK_ RPEPSTLENITDDKYATVS(0.103)S(0.402)PS(0.495)K RPEPS(-109.21)T(-109.21)LENIT(-93.55)DDKY(-57.2)AT(-30.39)VS(-6.82)S(-0.91)PS(0.91)K 22 3 872.41273 1.2966 0 0 0 0 0 0 0 0 1001 771 386 386 2419;5253 2742;5981 22608 14102 Mix4_TiO2_Reinj_1_3 4890 22608 14102 Mix4_TiO2_Reinj_1_3 4890 Q01813 Q01813 Q01813 >sp|Q01813|K6PP_HUMAN 6-phosphofructokinase type C OS=Homo sapiens GN=PFKP PE=1 SV=2 1 112.17 1 97.1826 0.00148775 97.576 1 112.17 0.00043939 112.17 1 S VRLRGRSFAGNLN CAMK2;PKA/AKT 0.001764 0.00043939 112.17 _GRpSFAGNLNTYK_ GRS(1)FAGNLNTYK GRS(112.17)FAGNLNT(-112.17)Y(-112.17)K 3 2 704.32447 0.2891 1184000 242030 0 0 941940 0 0 0 1002 773 310 310 5738 6539 56402 34447 Mix4_TiO2_Reinj_1_4 8148 56401 34446 Mix4_TiO2_1_4 7436 Q01850 Q01850 Q01850 >sp|Q01850|CDR2_HUMAN Cerebellar degeneration-related protein 2 OS=Homo sapiens GN=CDR2 PE=1 SV=2 0.331711 0 0.225094 -1.59141 3.01109E-06 112.39 0 0 0.331711 0 0.00117625 87.631 1 S KPLKRSSSETILS PKA 0.042 3.01109E-06 112.39 _SpSSETILSSLAGSDIVK_ S(0.258)S(0.332)S(0.332)ET(0.078)ILSSLAGSDIVK S(-1.09)S(0)S(0)ET(-6.27)ILS(-36.6)S(-37.47)LAGS(-83.08)DIVK 2 2 887.42952 0.18894 0 0 0 0 0 0 0 0 1003 773 311 311 5738 6539 56402 34447 Mix4_TiO2_Reinj_1_4 8148 56401 34446 Mix4_TiO2_1_4 7436 Q01850 Q01850 Q01850 >sp|Q01850|CDR2_HUMAN Cerebellar degeneration-related protein 2 OS=Homo sapiens GN=CDR2 PE=1 SV=2 0.331711 0 0.225094 -1.59141 3.01109E-06 112.39 0 0 0.331711 0 0.00117625 87.631 1 S PLKRSSSETILSS CAMK2;CHK1;CHK1/2;PKA;PKA/AKT;PKD 0.00111111 3.01109E-06 112.39 _SpSSETILSSLAGSDIVK_ S(0.258)S(0.332)S(0.332)ET(0.078)ILSSLAGSDIVK S(-1.09)S(0)S(0)ET(-6.27)ILS(-36.6)S(-37.47)LAGS(-83.08)DIVK 3 2 887.42952 0.18894 0 0 0 0 0 0 0 0 1004 774 776 776 5868 6692 57890 35184 Mix4_TiO2_1_5 5561 57890 35184 Mix4_TiO2_1_5 5561 Q01973;Q01973-2 Q01973 Q01973 >sp|Q01973|ROR1_HUMAN Tyrosine-protein kinase transmembrane receptor ROR1 OS=Homo sapiens GN=ROR1 PE=2 SV=2;>sp|Q01973-2|ROR1_HUMAN Isoform T-ROR1 of Tyrosine-protein kinase transmembrane receptor ROR1 OS=Homo sapiens GN=ROR1 0.944404 13.7159 0.944404 13.7159 0.0011071 92.477 0 0 1 S TTSLSASPVSNLS CK1;NEK6;Proline-directed 0.05 0.0011071 92.477 _SWEGLSSHTSSTTPSGGNATTQTTSLSApSPVSNLSNPR_ SWEGLSSHTSSTTPSGGNATTQTT(0.001)S(0.002)LS(0.04)AS(0.944)PVS(0.011)NLS(0.001)NPR S(-69.84)WEGLS(-59.96)S(-59.96)HT(-59.96)S(-59.96)S(-60.16)T(-60.16)T(-60.16)PS(-48.64)GGNAT(-41.05)T(-41.82)QT(-37.87)T(-32.14)S(-26.19)LS(-13.72)AS(13.72)PVS(-19.24)NLS(-29.51)NPR 29 3 1295.5905 -1.6932 156940 156940 0 0 0 0 0 0 1005 775 729 729 2196 2486;2487 20152 12397 Mix4_TiO2_1_3 7918 20152 12397 Mix4_TiO2_1_3 7918 Q02156 Q02156 Q02156 >sp|Q02156|KPCE_HUMAN Protein kinase C epsilon type OS=Homo sapiens GN=PRKCE PE=1 SV=1 0.999998 56.2564 0.999998 56.2564 0.0102586 61.783 0.999982 47.4472 0.0108736 60.27 1 S EEFKGFSYFGEDL PDK1 0.0001168 0.0102586 61.783 _GFpSYFGEDLM(ox)P_ GFS(1)YFGEDLMP GFS(56.26)Y(-56.26)FGEDLMP 3 2 679.75416 -0.41227 112970 43241 0 0 69732 0 0 0 1006 775 334 334 3478;3479 3925;3927 32787 20316 Mix4_InSol_TiO2_1 4025 32781 20314 Mix4_TiO2_Reinj_1_3 4005 Q02156 Q02156 Q02156 >sp|Q02156|KPCE_HUMAN Protein kinase C epsilon type OS=Homo sapiens GN=PRKCE PE=1 SV=1 0.78115 7.16587 0.000785749 -30.7464 8.92735E-25 174.81 0.00609172 -21.9366 1.37687E-38 196.9 0.78115 7.16587 0.125502 51.696 0 0 1 S ESPQPASGSSPSE 1.37687E-38 196.9 _LIAGAESPQPApSGSSPSEEDRSK_ LIAGAES(0.001)PQPAS(0.781)GS(0.15)S(0.03)PS(0.03)EEDRS(0.009)K LIAGAES(-31.11)PQPAS(7.17)GS(-7.17)S(-14.2)PS(-14.2)EEDRS(-19.5)K 12 3 794.02699 -0.10682 68781 0.7096 0 0 0 0 0 68781 0 1007 775 337 337 3478;3479 3925;3927 32781 20314 Mix4_TiO2_Reinj_1_3 4005 32781 20314 Mix4_TiO2_Reinj_1_3 4005 Q02156 Q02156 Q02156 >sp|Q02156|KPCE_HUMAN Protein kinase C epsilon type OS=Homo sapiens GN=PRKCE PE=1 SV=1 0.951485 15.7546 0.933091 13.7258 8.92735E-25 174.81 0.951485 15.7546 1.37687E-38 196.9 0.0297277 -14.1957 0.125502 51.696 0 0 1 S QPASGSSPSEEDR CK1;CK2;Polo box;Proline-directed 0.00405 1.37687E-38 196.9 _LIAGAESPQPASGSpSPSEEDR_ LIAGAESPQPAS(0.006)GS(0.017)S(0.951)PS(0.025)EEDR LIAGAES(-137.14)PQPAS(-21.94)GS(-17.45)S(15.75)PS(-15.75)EEDR 15 2 1082.9733 -0.21204 581130 5.9955 165660 0 0 415480 0 0 0 1008 777 71 71 3222;5708;5709 3654;6505;6506 56075 34304 Mix4_TiO2_Reinj_1_6 5405 56073 34302 Mix4_TiO2_1_6 4711 Q02543 Q02543 Q02543 >sp|Q02543|RL18A_HUMAN 60S ribosomal protein L18a OS=Homo sapiens GN=RPL18A PE=1 SV=2 1 114.513 1 150.629 4.8598E-21 165.53 1 114.513 6.78244E-17 156.01 0 0 1 108.994 7.89455E-10 120.35 0.999999 66.7868 0.016049 66.787 1 S GQVFEKSPLRVKN CDK1;CDK2;Proline-directed 0.0057 4.8598E-21 165.53 _SSGEIVYCGQVFEKpSPLR_ SSGEIVYCGQVFEKS(1)PLR S(-119.44)S(-118.83)GEIVY(-114.51)CGQVFEKS(114.51)PLR 15 2 1068.4952 0.19154 2328500 288500 0 0 1348300 0 417920 273720 1009 778 385 385 5036;5151 5728;5865 49939 30533 Mix4_TiO2_Reinj_1_3 9270 49940 30534 Mix4_TiO2_Reinj_1_4 9082 Q02750 Q02750 Q02750 >sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2 0.476288 0 0.474806 0 1.63718E-47 207.85 0.470431 0 1.27964E-05 98.124 0.476288 0 2.09752E-60 229.46 0.476252 0 6.17936E-60 220.97 1 S IGLNQPSTPTHAA 2.09752E-60 229.46 _SDAEEVDFAGWLCSTIGLNQPpSTPTHAAGV_ SDAEEVDFAGWLCSTIGLNQPS(0.476)T(0.476)PT(0.047)HAAGV S(-192.49)DAEEVDFAGWLCS(-111.98)T(-111.98)IGLNQPS(0)T(0)PT(-10.02)HAAGV 22 3 1070.8077 -0.070043 0 0 0 0 0 0 0 0 1010 782 37 37 369;370 420;421;422;423 3511 2094 Mix4_InSol_Tio2_Reinj_1 5020 3506 2089 Mix4_InSol_TiO2_1 5071 Q03135 Q03135 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CAV1 PE=1 SV=4 1 120.46 1 40.4428 7.7388E-06 103.45 1 37.2681 0.120911 37.268 1 92.5823 6.98277E-09 118.33 0 0 1 139.991 4.44367E-16 159.12 1 120.46 2.17023E-13 154.2 1 S AMADELSEKQVYD 4.44367E-16 159.12 _AMADELpSEKQVYDAHTK_ AMADELS(1)EKQVYDAHTK AMADELS(120.46)EKQVY(-122.81)DAHT(-120.46)K 7 2 1008.4426 -0.15706 26789000 1470000 111060 0 9351000 0 8685100 7172200 1011 782 2 2 5301 6036 51494 31522 Mix4_InSol_Tio2_Reinj_1 6717 51493 31521 Mix4_InSol_TiO2_1 6744 Q03135 Q03135 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CAV1 PE=1 SV=4 0.998982 30.1286 0 0 0 0 0.97872 16.6305 2.57439E-06 110.89 0.998982 30.1286 0.0328815 58.966 1 S _____MSGGKYVD 2.57439E-06 110.89 _(ac)pSGGKYVDSEGHLYTVPIR_ S(0.999)GGKYVDS(0.001)EGHLYTVPIR S(30.13)GGKY(-43.44)VDS(-30.13)EGHLY(-58.97)T(-58.97)VPIR 1 2 1050.4935 0.10701 635330 0 0 0 0 0 380530 254800 1012 782 9 9 5301;6818 6036;7802 69124 42382 Mix4_TiO2_Reinj_1_6 5165 69124 42382 Mix4_TiO2_Reinj_1_6 5165 Q03135 Q03135 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CAV1 PE=1 SV=4 1 85.6247 0.999618 34.183 0.00011301 108.46 0 0 1 85.6247 4.38321E-07 132.91 0.021262 -16.6305 2.57439E-06 110.89 0.000969845 -30.1286 0.0328815 58.966 1 S GGKYVDSEGHLYT 4.38321E-07 132.91 _YVDpSEGHLYTVPIR_ YVDS(1)EGHLYTVPIR Y(-85.62)VDS(85.62)EGHLY(-106.73)T(-99.92)VPIR 4 2 864.90328 -0.24053 497070 94776 0 0 402290 0 0 0 1013 783 6 6 113 131;132 1214 776 Mix4_TiO2_Reinj_1_6 3423 1183 773 Mix4_TiO2_Reinj_1_6 4023 Q03135-2 Q03135-2 Q03135-2 >sp|Q03135-2|CAV1_HUMAN Isoform Beta of Caveolin-1 OS=Homo sapiens GN=CAV1 1 84.9117 1 95.0835 4.24952E-07 125.83 1 66.0023 7.05804E-05 103.7 1 84.9117 1.36659E-09 150.85 0.999881 39.5599 0.0774 50.816 1 71.89 4.00161E-07 126.51 1 84.4638 4.02093E-09 139.48 1 S _MADELSEKQVYD 1.36659E-09 150.85 _ADELpSEKQVYDAHTK_ ADELS(1)EKQVYDAHTK ADELS(84.91)EKQVY(-84.91)DAHT(-86.48)K 5 3 605.27165 0.5339 36266000 3997800 611580 0 11683000 41181 9865700 10067000 1014 784 17 17 237 272 2349 1501 Mix4_InSol_TiO2_1 4122 2351 1503 Mix4_TiO2_1_3 3044 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.867245 11.1612 0.385892 -2.01677 0.0103589 72.583 0.135553 -7.30557 0.227973 29.396 0.0832585 -10.0047 0.591757 10.005 0.867245 11.1612 0.565146 11.161 0 0 1 S GPATPLSPTRLSR CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0103589 72.583 _AGGPATPLpSPTR_ AGGPAT(0.066)PLS(0.867)PT(0.066)R AGGPAT(-11.16)PLS(11.16)PT(-11.16)R 9 2 602.78973 0.33322 35083 0 0 0 0 0 35083 0 1015 784 400 400 587 674 5585 3319 Mix4_TiO2_1_3 1935 5586 3320 Mix4_TiO2_Reinj_1_3 2411 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.469597 0 0.469597 0 0.0011545 93.186 4.89773E-05 -42.9705 3.40475E-07 133.91 2.29529E-05 -46.1754 0.00265 84.156 0.431755 0 0.0116101 71.759 1 S VSRATSSSSGSLS GSK3 0.081 3.40475E-07 133.91 _ATSpSSSGSLSATGR_ ATS(0.001)S(0.47)S(0.47)S(0.059)GS(0.001)LSATGR AT(-36.26)S(-28.38)S(0)S(0)S(-9.01)GS(-26.67)LS(-53.62)AT(-93.19)GR 4 2 674.79065 0.039952 0 0 0 0 0 0 0 0 1016 784 401 401 587 674 5585 3319 Mix4_TiO2_1_3 1935 5586 3320 Mix4_TiO2_Reinj_1_3 2411 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.469597 0 0.469597 0 0.0011545 93.186 3.2733E-05 -44.7206 3.40475E-07 133.91 1.70936E-05 -47.4555 0.00265 84.156 0.431755 0 0.0116101 71.759 1 S SRATSSSSGSLSA 3.40475E-07 133.91 _ATSpSSSGSLSATGR_ ATS(0.001)S(0.47)S(0.47)S(0.059)GS(0.001)LSATGR AT(-36.26)S(-28.38)S(0)S(0)S(-9.01)GS(-26.67)LS(-53.62)AT(-93.19)GR 5 2 674.79065 0.039952 0 0 0 0 0 0 0 0 1017 784 404 404 587 674 5586 3320 Mix4_TiO2_Reinj_1_3 2411 5586 3320 Mix4_TiO2_Reinj_1_3 2411 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.970617 16.235 0.00101078 -26.6707 0.0011545 93.186 0.970617 16.235 3.40475E-07 133.91 0.028413 -15.2486 0.00265 84.156 0.000543799 -28.998 0.0116101 71.759 1 S TSSSSGSLSATGR CK1 0.081 3.40475E-07 133.91 _ATSSSSGpSLSATGR_ ATSSSS(0.023)GS(0.971)LS(0.006)ATGR AT(-78.53)S(-70.27)S(-42.97)S(-44.72)S(-16.24)GS(16.24)LS(-21.94)AT(-85.46)GR 8 2 674.79065 -0.51932 518480 0 0 0 518480 0 0 0 1018 784 406 406 587 674 5583 3312 Mix4_InSol_TiO2_1 2671 5586 3320 Mix4_TiO2_Reinj_1_3 2411 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.951433 15.2486 2.03979E-06 -53.6214 0.0011545 93.186 0.00620442 -21.9435 3.40475E-07 133.91 0.951433 15.2486 0.00265 84.156 4.52604E-07 -59.7952 0.0116101 71.759 1 S SSSGSLSATGRLG CK1 0.143 3.40475E-07 133.91 _ATSSSSGSLpSATGR_ ATSSSSGS(0.028)LS(0.951)AT(0.02)GR AT(-77.05)S(-69.94)S(-46.18)S(-47.46)S(-40.94)GS(-15.25)LS(15.25)AT(-16.77)GR 10 2 674.79065 -0.5124 158780 0 0 0 0 0 158780 0 1019 790 1231 1231 1371 1542 12885 7950 Mix4_TiO2_Reinj_1_5 5719 12883 7947 Mix4_TiO2_Reinj_1_1 5103 Q04637;Q04637-3;Q04637-4;Q04637-5;Q04637-6 Q04637 Q04637 >sp|Q04637|IF4G1_HUMAN Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens GN=EIF4G1 PE=1 SV=4;>sp|Q04637-3|IF4G1_HUMAN Isoform B of Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens GN=EIF4G1;>sp|Q04637-4|IF4G1_HUMAN Isofor 1 38.5579 1 36.7242 0.125303 36.724 0 0 1 38.5579 0.0640235 44.476 0 0 1 S AALPPVSPLKAAL CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0640235 44.476 _EAALPPVpSPLK_ EAALPPVS(1)PLK EAALPPVS(38.56)PLK 8 2 601.31505 0.22176 264600 51997 0 0 212600 0 0 0 1020 790 1187 1187 5274 6002 51184 31372 Mix4_InSol_TiO2_1 4642 51187 31375 Mix4_TiO2_Reinj_1_1 3812 Q04637;Q04637-3;Q04637-4;Q04637-5;Q04637-6 Q04637 Q04637 >sp|Q04637|IF4G1_HUMAN Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens GN=EIF4G1 PE=1 SV=4;>sp|Q04637-3|IF4G1_HUMAN Isoform B of Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens GN=EIF4G1;>sp|Q04637-4|IF4G1_HUMAN Isofor 0.999924 41.1878 0.817179 6.50291 0.595467 13.09 0.999919 40.8973 0.00696772 63.751 0.999924 41.1878 0.027188 54.277 0.984082 17.9114 0.0215133 56.074 1 S ATKRSFSKEVEER CAMK2;PKA 0.003024 0.00696772 63.751 _SFpSKEVEER_ SFS(1)KEVEER S(-41.19)FS(41.19)KEVEER 3 2 595.75809 0.12266 308700 22556 0 0 176560 0 60607 48973 1021 791 284 284 746 852 7263 4292 Mix4_InSol_Tio2_Reinj_1 3911 7264 4293 Mix4_TiO2_1_3 2986 Q04724 Q04724 Q04724 >sp|Q04724|TLE1_HUMAN Transducin-like enhancer protein 1 OS=Homo sapiens GN=TLE1 PE=1 SV=2 0.430072 0 0.0336152 -12.7037 0.000417655 91.741 0.000301461 -31.519 0.00127353 79.378 0 0 0.430072 0 0.0926843 51.38 1 S LLKKDASSSPAST CHK1;PKD 0.020748 0.000417655 91.741 _DApSSSPASTASSASSTSLK_ DAS(0.43)S(0.43)S(0.118)PAS(0.018)T(0.004)ASSASSTSLK DAS(0)S(0)S(-5.63)PAS(-13.7)T(-20.56)AS(-37.84)S(-51.38)AS(-51.38)S(-51.38)T(-51.38)S(-51.38)LK 3 2 911.39112 0.0074978 0 0 0 0 0 0 0 0 1022 791 285 285 746 852 7263 4292 Mix4_InSol_Tio2_Reinj_1 3911 7264 4293 Mix4_TiO2_1_3 2986 Q04724 Q04724 Q04724 >sp|Q04724|TLE1_HUMAN Transducin-like enhancer protein 1 OS=Homo sapiens GN=TLE1 PE=1 SV=2 0.430072 0 0.334127 -2.72989 0.000417655 91.741 0.0708941 -7.80524 0.00127353 79.378 0 0 0.430072 0 0.0926843 51.38 1 S LKKDASSSPASTA GSK3 0.081 0.000417655 91.741 _DApSSSPASTASSASSTSLK_ DAS(0.43)S(0.43)S(0.118)PAS(0.018)T(0.004)ASSASSTSLK DAS(0)S(0)S(-5.63)PAS(-13.7)T(-20.56)AS(-37.84)S(-51.38)AS(-51.38)S(-51.38)T(-51.38)S(-51.38)LK 4 2 911.39112 0.0074978 0 0 0 0 0 0 0 0 1023 791 286 286 746 852 7264 4293 Mix4_TiO2_1_3 2986 7264 4293 Mix4_TiO2_1_3 2986 Q04724 Q04724 Q04724 >sp|Q04724|TLE1_HUMAN Transducin-like enhancer protein 1 OS=Homo sapiens GN=TLE1 PE=1 SV=2 0.626471 2.72989 0.626471 2.72989 0.000417655 91.741 0.427695 0 0.00127353 79.378 0 0 0.117629 -5.63028 0.0926843 51.38 1 S KKDASSSPASTAS Polo box;Proline-directed 0.00405 0.000417655 91.741 _DASSpSPASTASSASSTSLK_ DAS(0.034)S(0.334)S(0.626)PAS(0.005)T(0.001)ASSASSTSLK DAS(-12.7)S(-2.73)S(2.73)PAS(-20.76)T(-30.83)AS(-49.57)S(-58.98)AS(-88.6)S(-87.98)T(-81.58)S(-91.74)LK 5 2 911.39112 -0.22203 55356 55356 0 0 0 0 0 0 1024 791 289 289 746 852 7265 4294 Mix4_TiO2_Reinj_1_3 3674 7264 4293 Mix4_TiO2_1_3 2986 Q04724 Q04724 Q04724 >sp|Q04724|TLE1_HUMAN Transducin-like enhancer protein 1 OS=Homo sapiens GN=TLE1 PE=1 SV=2 0.427695 0 0.00526193 -20.7576 0.000417655 91.741 0.427695 0 0.00127353 79.378 0 0 0.0183609 -13.6965 0.0926843 51.38 1 S ASSSPASTASSAS CK1;GSK3 0.081 0.000417655 91.741 _DASSpSPASTASSASSTSLK_ DASS(0.071)S(0.428)PAS(0.428)T(0.071)AS(0.002)SASSTSLK DAS(-31.52)S(-7.81)S(0)PAS(0)T(-7.81)AS(-23.02)S(-30.42)AS(-59.27)S(-78.71)T(-71.25)S(-77.35)LK 8 2 911.39112 0.22075 0 0 0 0 0 0 0 0 1025 792 286 286 736 842 7124 4232 Mix4_InSol_Tio2_Reinj_1 3702 7125 4235 Mix4_TiO2_1_3 2888 Q04726;Q04726-4;Q04726-3;Q04726-2 Q04726 Q04726 >sp|Q04726|TLE3_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=1 SV=2;>sp|Q04726-4|TLE3_HUMAN Isoform 4 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3;>sp|Q04726-3|TLE3_HUMAN Isoform 3 of Transducin-like enhancer protein 0.898601 9.49065 0.894436 9.32575 1.755E-15 140.18 0 0 0.820606 6.74 9.11526E-05 97.318 0.816751 7.52475 0.00071771 86.616 0.898601 9.49065 0.00057038 89.133 1 S KKDAPTSPASVAS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.755E-15 140.18 _DAPTpSPASVASSSSTPSSK_ DAPT(0.101)S(0.899)PASVASSSSTPSSK DAPT(-9.49)S(9.49)PAS(-34.01)VAS(-78.99)S(-78.44)S(-85.06)S(-89.13)T(-89.13)PS(-89.13)S(-89.13)K 5 2 922.40149 0.073471 1124300 389140 0 0 269970 0 251510 213690 1026 792 289 289 736 842 7127 4237 Mix4_TiO2_Reinj_1_3 3449 7125 4235 Mix4_TiO2_1_3 2888 Q04726;Q04726-4;Q04726-3;Q04726-2 Q04726 Q04726 >sp|Q04726|TLE3_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=1 SV=2;>sp|Q04726-4|TLE3_HUMAN Isoform 4 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3;>sp|Q04726-3|TLE3_HUMAN Isoform 3 of Transducin-like enhancer protein 0.345047 0 0.104466 -9.32575 1.755E-15 140.18 0 0 0.345047 0 9.11526E-05 97.318 0.0388022 -13.2323 0.00071771 86.616 0.000356529 -34.0147 0.00057038 89.133 1 S APTSPASVASSSS CK1;GSK3 0.081 1.755E-15 140.18 _DAPTpSPASVASSSSTPSSK_ DAPT(0.306)S(0.345)PAS(0.345)VAS(0.001)S(0.002)SSTPSSK DAPT(-0.52)S(0)PAS(0)VAS(-23.93)S(-22.63)S(-30.42)S(-54.02)T(-72.82)PS(-97.32)S(-97.32)K 8 2 922.40149 0.272 0 0 0 0 0 0 0 0 1027 792 203 203 1833 2070 16803 10118 Mix4_TiO2_1_3 3059 16803 10118 Mix4_TiO2_1_3 3059 Q04726;Q04726-4;Q04726-3;Q04726-2 Q04726 Q04726 >sp|Q04726|TLE3_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=1 SV=2;>sp|Q04726-4|TLE3_HUMAN Isoform 4 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3;>sp|Q04726-3|TLE3_HUMAN Isoform 3 of Transducin-like enhancer protein 0.998854 29.8803 0.998854 29.8803 3.40471E-09 142.12 0 0 0 0 0 0 1 S SANNSVSPSESLR CK2;GSK3;Proline-directed 0.05 3.40471E-09 142.12 _ESSANNSVpSPSESLR_ ESSANNS(0.001)VS(0.999)PSESLR ES(-79.26)S(-79.26)ANNS(-29.88)VS(29.88)PS(-40.52)ES(-45.17)LR 9 2 822.34906 0.77196 184190 184190 0 0 0 0 0 0 1028 797 774 774 5046 5739;5740 48798 29824 Mix4_TiO2_1_5 1240 48799 29826 Mix4_TiO2_Reinj_1_3 1656 Q05193;Q05193-2;Q05193-4;Q05193-3;Q05193-5 Q05193 Q05193 >sp|Q05193|DYN1_HUMAN Dynamin-1 OS=Homo sapiens GN=DNM1 PE=1 SV=2;>sp|Q05193-2|DYN1_HUMAN Isoform 2 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-4|DYN1_HUMAN Isoform 4 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-3|DYN1_HUMAN Isoform 3 of Dynamin-1 O 0.822484 12.8811 0.822484 12.8811 0.134246 35.959 0.390689 -1.2971 0.214363 29.101 2 S VPAGRRSPTSSPT GSK3;PKA;Proline-directed 0.042 0.00178588 103.23 _RpSPpTSSPTPQR_ RS(0.822)PT(0.663)S(0.158)S(0.224)PT(0.132)PQR RS(12.88)PT(6.28)S(-9.16)S(-6.28)PT(-11.23)PQR 2 2 687.28416 -0.13509 15256 15256 0 0 0 0 0 0 1029 797 778 778 5046 5739;5740 48799 29826 Mix4_TiO2_Reinj_1_3 1656 48799 29826 Mix4_TiO2_Reinj_1_3 1656 Q05193;Q05193-2;Q05193-4;Q05193-3;Q05193-5 Q05193 Q05193 >sp|Q05193|DYN1_HUMAN Dynamin-1 OS=Homo sapiens GN=DNM1 PE=1 SV=2;>sp|Q05193-2|DYN1_HUMAN Isoform 2 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-4|DYN1_HUMAN Isoform 4 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-3|DYN1_HUMAN Isoform 3 of Dynamin-1 O 0.555933 2.16058 0.223892 -6.28429 0.134246 35.959 0.555933 2.16058 0.00178588 103.23 2 S RRSPTSSPTPQRR CK1;Polo box;Proline-directed 0.00405 0.00178588 103.23 _RSPpTSpSPTPQR_ RS(0.007)PT(0.993)S(0.106)S(0.556)PT(0.338)PQR RS(-21.78)PT(21.78)S(-7.2)S(2.16)PT(-2.16)PQR 6 2 687.28416 -0.2913 262200 0 0 0 262200 0 0 0 1030 798 673 673 1302 1469 12179 7460 Mix4_TiO2_Reinj_1_5 5228 12178 7459 Mix4_TiO2_1_5 4463 Q05209 Q05209 Q05209 >sp|Q05209|PTN12_HUMAN Tyrosine-protein phosphatase non-receptor type 12 OS=Homo sapiens GN=PTPN12 PE=1 SV=2 0.999994 51.9318 0.999966 44.6653 3.13841E-09 143.26 0.999994 51.9318 5.37137E-07 122.75 1 S VDVSEDSPPPLPE CK1;Proline-directed 0.05 3.13841E-09 143.26 _DVDVSEDpSPPPLPER_ DVDVSEDS(1)PPPLPER DVDVS(-51.93)EDS(51.93)PPPLPER 8 2 866.37729 0.26297 525750 119410 0 0 406340 0 0 0 1031 798 435 435 4162 4738 39666 24472 Mix4_TiO2_Reinj_1_5 6566 39665 24471 Mix4_TiO2_Reinj_1_3 6629 Q05209 Q05209 Q05209 >sp|Q05209|PTN12_HUMAN Tyrosine-protein phosphatase non-receptor type 12 OS=Homo sapiens GN=PTPN12 PE=1 SV=2 1 35.9233 1 27.7596 0.295442 27.76 1 35.9233 0.129774 49.602 1 5.90467 0.959268 5.9047 0 0 1 S KLERNLSFEIKKV CAMK2;CHK1;CHK1/2;PKD 0.003192 0.129774 49.602 _NLpSFEIK_ NLS(1)FEIK NLS(35.92)FEIK 3 2 465.72025 -0.42349 307170 49899 0 0 199930 0 57341 0 1032 798 507 507 6622 7581 67149 41193 Mix4_TiO2_1_5 3538 67150 41195 Mix4_TiO2_Reinj_1_5 4207 Q05209 Q05209 Q05209 >sp|Q05209|PTN12_HUMAN Tyrosine-protein phosphatase non-receptor type 12 OS=Homo sapiens GN=PTPN12 PE=1 SV=2 0.499687 0 0.499687 0 0.215384 40.384 4.25751E-05 -42.2842 0.000679289 80.158 1 S TQSNKVSVTPPEE AURORA;AURORA-1;AURORA-A;CK1 0.006142092 0.000679289 80.158 _VpSVTPPEESQNSDTPPRPDR_ VS(0.5)VT(0.5)PPEESQNSDTPPRPDR VS(0)VT(0)PPEES(-30.58)QNS(-35.42)DT(-40.38)PPRPDR 2 3 763.34454 0.21056 0 0 0 0 0 0 0 0 1033 798 517 517 6622 7581 67150 41195 Mix4_TiO2_Reinj_1_5 4207 67150 41195 Mix4_TiO2_Reinj_1_5 4207 Q05209 Q05209 Q05209 >sp|Q05209|PTN12_HUMAN Tyrosine-protein phosphatase non-receptor type 12 OS=Homo sapiens GN=PTPN12 PE=1 SV=2 0.720405 4.1493 0.000143515 -35.418 0.215384 40.384 0.720405 4.1493 0.000679289 80.158 1 S PEESQNSDTPPRP CK1 0.081 0.000679289 80.158 _VSVTPPEESQNpSDTPPRPDR_ VSVT(0.001)PPEES(0.001)QNS(0.72)DT(0.277)PPRPDR VS(-42.28)VT(-27.24)PPEES(-28.22)QNS(4.15)DT(-4.15)PPRPDR 12 3 763.34454 0.074564 106870 0 0 0 106870 0 0 0 1034 799 16 16 24 32 259 154 Mix4_TiO2_1_5 5614 262 157 Mix4_TiO2_Reinj_1_5 6506 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.284155 0 0.284155 0 1.18667E-15 149.93 0.00506049 -22.9323 6.86721E-06 98.828 0.0355844 -14.3297 3.82093E-22 175.14 0.00257418 -25.8778 0.0103134 71.846 0.231271 0 5.69392E-10 125.08 1 S LNHTPNSSTKTHL 3.82093E-22 175.14 _(ac)AAAYLDPNLNHTPNpSSTK_ AAAY(0.046)LDPNLNHT(0.102)PNS(0.284)S(0.284)T(0.284)K AAAY(-7.93)LDPNLNHT(-4.46)PNS(0)S(0)T(0)K 15 3 679.30888 0.058166 0 0 0 0 0 0 0 0 1035 799 17 17 24 32 259 154 Mix4_TiO2_1_5 5614 262 157 Mix4_TiO2_Reinj_1_5 6506 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.284155 0 0.284155 0 1.18667E-15 149.93 0.000759452 -31.1692 6.86721E-06 98.828 0.00103523 -29.8361 3.82093E-22 175.14 0.0019221 -27.1106 0.0103134 71.846 0.231271 0 5.69392E-10 125.08 1 S NHTPNSSTKTHLG CK1 0.143 3.82093E-22 175.14 _(ac)AAAYLDPNLNHTPNpSSTK_ AAAY(0.046)LDPNLNHT(0.102)PNS(0.284)S(0.284)T(0.284)K AAAY(-7.93)LDPNLNHT(-4.46)PNS(0)S(0)T(0)K 16 3 679.30888 0.058166 0 0 0 0 0 0 0 0 1036 799 840 840 2015 2283 18491 11206 Mix4_TiO2_Reinj_1_5 5238 18490 11205 Mix4_TiO2_Reinj_1_3 5195 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 1 30.8452 0 0 0 0 1 30.8452 0.0411182 48.966 0 0 0 0 0 0 1 S KPDVRLSRGSIDR PKA 0.042 0.0411182 48.966 _FLKPDVRLpSR_ FLKPDVRLS(1)R FLKPDVRLS(30.85)R 9 2 655.85266 0.30389 1497800 0 0 0 1497800 0 0 0 1037 799 843 843 2445 2772 22992 14379 Mix4_TiO2_Reinj_1_5 5649 22989 14375 Mix4_TiO2_Reinj_1_5 5349 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.997332 25.7482 0.877687 8.89915 1.70097 27.681 0 0 0.997332 25.7482 0.000441628 80.159 1 S VRLSRGSIDREDG AURORA;AURORA-1;CK1;PKA 0.020748 0.000441628 80.159 _GpSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPK_ GS(0.997)IDREDGS(0.003)LQGPIGNQHIYQPVGKPDPAAPPK GS(25.75)IDREDGS(-25.75)LQGPIGNQHIY(-48.64)QPVGKPDPAAPPK 2 3 1173.5736 0.060107 7961500 127660 0 0 7833800 0 0 0 1038 799 893 893 3159 3586 29981 18638 Mix4_TiO2_Reinj_1_5 5895 29981 18638 Mix4_TiO2_Reinj_1_5 5895 Q05397;Q05397-2 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 0.748673 7.29176 0.748673 7.29176 1.89366E-12 128.78 1 S SLASLSSPADSYN CK1;CK2;GSK3;Polo box;Proline-directed 0.00405 1.89366E-12 128.78 _KPPRPGAPGHLGSLASLSpSPADSYNEGVK_ KPPRPGAPGHLGS(0.001)LAS(0.109)LS(0.14)S(0.749)PADS(0.001)Y(0.001)NEGVK KPPRPGAPGHLGS(-27.56)LAS(-8.38)LS(-7.29)S(7.29)PADS(-30.49)Y(-29.52)NEGVK 19 3 990.48874 0.50273 613420 0 0 0 613420 0 0 0 1039 799 568 568 3434 3878 32229 19908 Mix4_TiO2_Reinj_1_5 6040 32227 19906 Mix4_TiO2_1_5 5055 Q05397;Q05397-2;Q05397-3;Q05397-4;Q14289;Q14289-2 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 1 69.4768 1 88.7078 0.00432038 88.708 1 69.4768 0.00621651 79.252 1 S LGDFGLSRYMEDS 0.00432038 88.708 _LGDFGLpSR_ LGDFGLS(1)R LGDFGLS(69.48)R 7 2 472.7155 -0.24558 334630 74105 0 0 260530 0 0 0 1040 799 910 910 3673 4144 34531 21468 Mix4_TiO2_1_5 4744 34530 21466 Mix4_TiO2_1_5 4769 Q05397;Q05397-2 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 0.99997 45.1723 0.99997 45.1723 9.09601E-17 174.38 0.999946 42.6748 2.26999E-16 172.06 0.999591 33.8822 3.32926E-12 139.65 0.767304 5.18179 0.690198 22.035 0.999332 31.7505 3.28937E-12 139.83 0.976849 16.2526 1.03092E-08 123.7 1 S LQPQEISPPPTAN Proline-directed 0.05 9.09601E-17 174.38 _LQPQEIpSPPPTANLDR_ LQPQEIS(1)PPPTANLDR LQPQEIS(45.17)PPPT(-45.17)ANLDR 7 3 619.30317 0.028449 21784000 4185200 686160 0 12587000 16133 2222700 2087100 1041 799 722 722 4422;4479 5031;5090 42106 25942 Mix4_TiO2_Reinj_1_5 3030 42478 26125 Mix4_TiO2_1_5 4474 Q05397;Q05397-2 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 0.998149 27.3186 0.800631 9.12175 2.17064E-07 101.51 0.798267 6.26736 0.0234521 63.294 0.998149 27.3186 8.8028E-05 92.722 0 0 0.983314 18.5971 0.0143024 69.709 0.774214 6.29579 0.0178485 67.223 1 S SRPGYPSPRSSEG CDK1;GSK3;Proline-directed 0.0057 2.17064E-07 101.51 _PGYPpSPR_ PGY(0.002)PS(0.998)PR PGY(-27.32)PS(27.32)PR 5 2 427.18384 0.41559 8332600 1123800 55029 0 5650200 0 891130 612490 1042 799 390 390 6013 6856;6857 59415 36063 Mix4_TiO2_1_5 5791 59417 36065 Mix4_TiO2_Reinj_1_5 6423 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.248459 0 0.248459 0 0.000204101 85.223 0 0 0.0871881 -9.27032 1.49544E-07 104.48 0 0 0.0761925 -5.99645 0.000263815 81.239 0.189793 -1.0342 0.0149515 70.965 1 S MRTHAVSVSETDD CK1;CK2 0.117 1.49544E-07 104.48 _THAVpSVSETDDYAEIIDEEDTYTM(ox)PSTR_ T(0.048)HAVS(0.248)VS(0.248)ET(0.248)DDY(0.206)AEIIDEEDTYTMPSTR T(-7.1)HAVS(0)VS(0)ET(0)DDY(-0.81)AEIIDEEDT(-63.48)Y(-68.89)T(-78.34)MPS(-85.22)T(-85.22)R 5 3 1091.1218 0.36264 0 0 0 0 0 0 0 0 1043 799 392 392 6013 6856;6857 59406 36059 Mix4_InSol_TiO2_1 7331 59417 36065 Mix4_TiO2_Reinj_1_5 6423 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.30308 0 0.248459 0 0.000204101 85.223 0 0 0.0871881 -9.27032 1.49544E-07 104.48 0 0 0.30308 0 0.000263815 81.239 0.189793 -1.0342 0.0149515 70.965 1 S THAVSVSETDDYA CK2 0.117 1.49544E-07 104.48 _THAVSVpSETDDYAEIIDEEDTYTMPSTR_ T(0.015)HAVS(0.076)VS(0.303)ET(0.303)DDY(0.303)AEIIDEEDTYTMPSTR T(-13.18)HAVS(-6)VS(0)ET(0)DDY(0)AEIIDEEDT(-62.96)Y(-66.9)T(-70.47)MPS(-74.61)T(-74.61)R 7 3 1085.7902 0.41264 0 0 0 0 0 0 0 0 1044 799 29 29 6014 6858;6859;6860 59445 36070 Mix4_TiO2_Reinj_1_5 2661 59445 36070 Mix4_TiO2_Reinj_1_5 2661 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.999978 49.631 0 0 0 0 0.999978 49.631 0.0943497 49.631 0.972243 18.4544 0.812569 18.454 0.923274 11.1285 0.683989 22.229 1 S GTGMERSPGAMER Proline-directed 0.05 0.0943497 49.631 _THLGTGM(ox)ERpSPGAM(ox)ER_ THLGTGMERS(1)PGAMER T(-49.63)HLGT(-49.63)GMERS(49.63)PGAMER 10 3 614.59385 0.79364 924660 0 0 0 119330 0 575600 229730 1045 800 645 645 467;468 530;531;532 4355 2620 Mix4_TiO2_1_4 2445 4356 2625 Mix4_TiO2_1_5 2501 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.993612 22.4248 0.993612 22.4248 0.00571784 71.616 0.942777 13.0517 0.384689 21.048 0.992969 22.1015 0.00713631 65.722 0 0 0.704205 6.77739 0.0166001 67.509 0.969415 16.5693 0.0408067 48.914 1 S NEKARLSYSDKNL CK2;PKA 0.042 0.00571784 71.616 _ARLpSYSDK_ ARLS(0.994)Y(0.006)S(0.001)DK ARLS(22.42)Y(-22.42)S(-31.5)DK 4 2 510.23151 0.12843 13689000 6497900 64473 0 6325100 0 72142 729440 1046 800 647 647 467;468 530;531;532 4350 2597 Mix4_InSol_TiO2_1 3293 4356 2625 Mix4_TiO2_1_5 2501 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.92178 10.9707 0.163905 -7.05174 0.00571784 71.616 0.0466919 -13.0517 0.384689 21.048 0.895299 9.34493 0.00713631 65.722 0 0 0.92178 10.9707 0.0166001 67.509 0.00922596 -20.215 0.0408067 48.914 1 S KARLSYSDKNLID NEK6 0.076 0.00571784 71.616 _ARLSYpSDK_ ARLS(0.074)Y(0.005)S(0.922)DK ARLS(-10.97)Y(-23.11)S(10.97)DK 6 2 510.23151 0.42091 30541000 0 0 0 29650000 0 890870 0 1047 800 664 664 468;4140 531;532;4714;4715 39470 24349 Mix4_TiO2_Reinj_1_4 8985 39468 24347 Mix4_TiO2_Reinj_1_3 9144 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 1 108.091 1 115.94 3.23072E-32 204.55 0 0 1 108.091 1.86943E-39 221.98 0 0 1 S SAFAGFSFVNPKF PDK1 0.0001168 1.86943E-39 221.98 _NLIDSMDQSAFAGFpSFVNPK_ NLIDSMDQSAFAGFS(1)FVNPK NLIDS(-162.11)MDQS(-108.09)AFAGFS(108.09)FVNPK 15 2 1134.5058 1.0951 15514000 2438100 0 0 13076000 0 0 0 1048 800 299 299 522;3514;3515 590;591;3967;3968 33171 20489 Mix4_InSol_TiO2_1 6682 33172 20491 Mix4_InSol_TiO2_1 6711 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 1 72.4049 0.971871 15.3845 0.0029378 79.546 0.997002 25.2191 0.0151528 68.838 1 72.4049 0.00280379 80.43 0.999514 33.1354 0.227969 37.067 1 S QVTQRASRRSDSA CK1;PKA 0.042 0.00280379 80.43 _LLAEALNQVTQRApSR_ LLAEALNQVTQRAS(1)R LLAEALNQVT(-72.4)QRAS(72.4)R 14 2 875.454 -0.037481 29562000 250230 0 0 1217600 0 16257000 11837000 1049 800 302 302 522;5037;5038;5178 590;591;5729;5730;5894 48707 29783 Mix4_TiO2_1_3 5335 50144 30650 Mix4_TiO2_Reinj_1_3 6623 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.988493 19.5845 0.988493 19.5845 4.61512E-26 188.69 0.882922 8.77455 1.35227E-33 218.03 0.623265 2.89917 3.23377E-10 126 0.306562 0 0.00103108 81.288 1 S QRASRRSDSASSE CK1;GSK3;PKA 0.042 1.35227E-33 218.03 _RpSDSASSEPVGIYQGFEK_ RS(0.988)DS(0.011)AS(0.001)SEPVGIYQGFEK RS(19.58)DS(-19.58)AS(-31.96)S(-81.9)EPVGIY(-156.42)QGFEK 2 2 1018.9517 0.15321 6612600 71.233 1071500 0 0 5294100 0 246930 0 1050 800 304 304 522;5037;5038;5178 590;591;5729;5730;5894 48700 29776 Mix4_InSol_TiO2_1 6618 50144 30650 Mix4_TiO2_Reinj_1_3 6623 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.858557 8.71762 0.616024 2.05295 4.61512E-26 188.69 0.721276 4.69323 1.35227E-33 218.03 0.858557 8.71762 3.23377E-10 126 0.830291 6.99881 0.00103108 81.288 1 S ASRRSDSASSEPV CAMK2;PKA/AKT 0.00111111 1.35227E-33 218.03 _RSDpSASSEPVGIYQGFEK_ RS(0.005)DS(0.859)AS(0.115)S(0.021)EPVGIYQGFEK RS(-22.29)DS(8.72)AS(-8.72)S(-16.11)EPVGIY(-96.43)QGFEK 4 2 1018.9517 0.032316 1943600 20.937 1023700 0 0 229810 0 373980 316030 1051 800 306 306 522;5037;5038;5178 590;591;5729;5730;5894 4896 2958 Mix4_InSol_Tio2_Reinj_1 6235 50144 30650 Mix4_TiO2_Reinj_1_3 6623 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.608147 5.71039 0.288857 -1.649 4.61512E-26 188.69 0.25 0 1.35227E-33 218.03 0.247526 0 3.23377E-10 126 0.608147 5.71039 0.00103108 81.288 1 S RRSDSASSEPVGI CK1 0.143 1.35227E-33 218.03 _ASRRSDSApSSEPVGIYQGFEK_ AS(0.043)RRS(0.142)DS(0.036)AS(0.608)S(0.163)EPVGIY(0.008)QGFEK AS(-11.48)RRS(-6.32)DS(-12.29)AS(5.71)S(-5.71)EPVGIY(-19.06)QGFEK 9 3 784.3603 -0.31156 127060 1.3688 0 0 0 0 0 0 127060 1052 800 307 307 522;5037;5038;5178 590;591;5729;5730;5894 48711 29790 Mix4_TiO2_Reinj_1_3 6132 50144 30650 Mix4_TiO2_Reinj_1_3 6623 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.25 0 0.25 0 4.61512E-26 188.69 0.25 0 1.35227E-33 218.03 0.247526 0 3.23377E-10 126 0.163294 -5.71039 0.00103108 81.288 1 S RSDSASSEPVGIY CK1 0.081 1.35227E-33 218.03 _RpSDSASSEPVGIYQGFEK_ RS(0.25)DS(0.25)AS(0.25)S(0.25)EPVGIYQGFEK RS(0)DS(0)AS(0)S(0)EPVGIY(-121.59)QGFEK 7 3 679.63688 0.59719 0 0 0 0 0 0 0 0 0 1053 800 506 506 541 615 5078 3085 Mix4_InSol_Tio2_Reinj_3 3805 5089 3112 Mix4_TiO2_1_4 8231 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.826559 6.81239 0.5 0 2.87622E-27 192.73 0.496878 0 0.708823 28.953 0.5 0 4.19236E-22 170.47 0.499725 0 0.501626 33.753 0.5 0 1.8212E-16 152.19 0.826559 6.81239 3.51132E-11 134.34 1 S FGESRASTFCGTP CK1;PKA 0.042 2.87622E-27 192.73 _ApSTFCGTPDYIAPEILQGLK_ AS(0.827)T(0.172)FCGT(0.001)PDYIAPEILQGLK AS(6.81)T(-6.81)FCGT(-28.26)PDY(-50.94)IAPEILQGLK 2 3 754.35684 -0.3849 68946000 5.6562 14212000 0 0 53382000 0 1036700 315150 1054 801 257 257 2426 2749 22745 14192 Mix4_InSol_Tio2_Reinj_1 7282 22744 14191 Mix4_InSol_TiO2_1 7307 Q06210;Q06210-2 Q06210 Q06210 >sp|Q06210|GFPT1_HUMAN Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 PE=1 SV=3;>sp|Q06210-2|GFPT1_HUMAN Isoform 2 of Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 0.498355 3.02482 0.0175472 -16.7245 0.000532196 84.212 0.498355 3.02482 0.00886518 70.266 1 S KGSCNLSRVDSTT CK1;CK2;GSK3 0.081 0.000532196 84.212 _GSCNLpSRVDSTTCLFPVEEK_ GS(0.001)CNLS(0.498)RVDS(0.248)T(0.248)T(0.004)CLFPVEEK GS(-27.39)CNLS(3.02)RVDS(-3.02)T(-3.02)T(-20.91)CLFPVEEK 6 3 793.6834 -0.22258 0 0 0 0 0 0 0 0 1055 801 261 261 2426;6372 2749;7288 64360 39493 Mix4_TiO2_1_3 5822 64360 39493 Mix4_TiO2_1_3 5822 Q06210;Q06210-2 Q06210 Q06210 >sp|Q06210|GFPT1_HUMAN Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 PE=1 SV=3;>sp|Q06210-2|GFPT1_HUMAN Isoform 2 of Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 0.998587 28.546 0.998587 28.546 3.94701E-06 142.94 0.437011 0 0.860998 5.957 0.928692 11.2039 0.00022029 112.27 0.986515 18.6755 0.00035189 107.75 0.991614 20.7739 0.00052565 101.78 1 S NLSRVDSTTCLFP CAMK2;CHK1;CHK1/2;CK1;PKD 0.003192 3.94701E-06 142.94 _VDpSTTCLFPVEEK_ VDS(0.999)T(0.001)TCLFPVEEK VDS(28.55)T(-28.55)T(-47.54)CLFPVEEK 3 2 802.84932 -0.54239 11119000 2319600 0 0 6367400 0 1613000 818860 1056 802 818 818 157 184 1735 1192 Mix4_TiO2_1_5 4648 1735 1192 Mix4_TiO2_1_5 4648 Q06418 Q06418 Q06418 >sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=Homo sapiens GN=TYRO3 PE=1 SV=1 0.999412 32.3057 0.999412 32.3057 0.0415529 57.245 0 0 1 S EPTAGGSLELPGR CK1 0.143 0.0415529 57.245 _AEEPTAGGpSLELPGR_ AEEPT(0.001)AGGS(0.999)LELPGR AEEPT(-32.31)AGGS(32.31)LELPGR 9 2 782.35616 0.00075878 26078 26078 0 0 0 0 0 0 1057 802 869 869 6742 7715 68352 41883 Mix4_TiO2_1_5 5762 68352 41883 Mix4_TiO2_1_5 5762 Q06418 Q06418 Q06418 >sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=Homo sapiens GN=TYRO3 PE=1 SV=1 0.992241 21.069 0.992241 21.069 0.0255446 64.768 0 0 1 S AEHQPESPLNETQ ERK/MAPK;Proline-directed;WW GroupIV 0.000145 0.0255446 64.768 _YILTPGGLAEQPGQAEHQPEpSPLNETQR_ YILTPGGLAEQPGQAEHQPES(0.992)PLNET(0.008)QR Y(-64.77)ILT(-57.88)PGGLAEQPGQAEHQPES(21.07)PLNET(-21.07)QR 21 3 1047.4943 0.067844 125300 0.56841 125300 0 0 0 0 0 0 1058 804 132 132 508;4813;4814 574;5463;5464 4723 2853 Mix4_TiO2_1_4 5478 45953 28104 Mix4_TiO2_Reinj_1_4 7657 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 0.999964 44.4733 0.999964 44.4733 0.0020978 75.386 0.998453 28.0975 0.145824 34.968 0.999455 32.6366 0.000600142 93.174 0.999619 34.1857 0.00380022 77.672 0.979644 16.8238 0.0108575 60.31 1 S RMSRRASLSDIGF AURORA;AURORA-1;AURORA-A;CAMK2;CHK1;CK1;CK2;PKA;PKA/AKT 0.00111111 0.000600142 93.174 _ApSLSDIGFGK_ AS(1)LSDIGFGK AS(44.47)LS(-44.47)DIGFGK 2 2 537.747 0.13082 11818000 2564500 71934 0 8071800 0 732780 377000 1059 804 134 134 508;4813;4814 574;5463;5464 45932 28085 Mix4_InSol_Tio2_Reinj_2 4615 45953 28104 Mix4_TiO2_Reinj_1_4 7657 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 0.5 0 0.014077 -18.4533 0.0020978 75.386 0.0015473 -28.0975 0.145824 34.968 0.166096 -7.00757 0.000600142 93.174 0.19462 -5.68039 0.00380022 77.672 0.5 0 0.0108575 60.31 1 S SRRASLSDIGFGK 0.000600142 93.174 _RApSLSDIGFGK_ RAS(0.5)LS(0.5)DIGFGK RAS(0)LS(0)DIGFGK 5 2 615.79755 0.056802 31305 0 0 0 0 0 0 31305 1060 804 74 74 1105 1243 10384 6395 Mix4_TiO2_Reinj_1_4 6272 10384 6395 Mix4_TiO2_Reinj_1_4 6272 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 1 114.306 1 113.806 1.95313E-18 144.12 1 114.306 4.33329E-19 153.89 1 S EEPGQLSPGVQFQ Proline-directed 0.05 4.33329E-19 153.89 _DPPQECSTFSPTDSGEEPGQLpSPGVQFQR_ DPPQECSTFSPTDSGEEPGQLS(1)PGVQFQR DPPQECS(-145.49)T(-142.19)FS(-134.02)PT(-118.42)DS(-114.31)GEEPGQLS(114.31)PGVQFQR 22 3 1086.4625 0.85745 2844200 1042300 0 0 1801900 0 0 0 1061 804 117 117 3668 4136;4137 34481 21429 Mix4_TiO2_Reinj_1_4 5313 34481 21429 Mix4_TiO2_Reinj_1_4 5313 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 0.999999 59.5243 0.999983 47.6896 0.0766995 47.69 0 0 0.999999 59.5243 0.0267703 59.524 0.999875 39.0254 0.0977615 42.663 0.997196 25.5096 0.413231 25.51 1 S QKLQMESPDLPKP Proline-directed 0.05 0.0267703 59.524 _LQM(ox)EpSPDLPKPLSR_ LQMES(1)PDLPKPLSR LQMES(59.52)PDLPKPLS(-59.52)R 5 3 569.61095 -0.17988 520760 123130 0 0 224220 0 98082 75323 1062 804 14 14 4872 5538 46753 28623 Mix4_TiO2_1_4 5242 46755 28626 Mix4_TiO2_Reinj_1_4 5912 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 0.999812 37.2516 0.999812 37.2516 0.00210847 101.89 0 0 0.999447 32.5714 0.00210847 101.89 0.404108 -1.68669 0.80674 13.493 0.406416 -1.64512 1.1474 4.8713 1 S NFKRRFSLSVPRT AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.00111111 0.00210847 101.89 _RFpSLSVPR_ RFS(1)LSVPR RFS(37.25)LS(-37.25)VPR 3 2 521.26569 -0.052697 3612700 727580 0 0 2885100 0 0 0 1063 804 16 16 4872 5538 46751 28621 Mix4_InSol_TiO2_1 6451 46755 28626 Mix4_TiO2_Reinj_1_4 5912 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 0.595892 1.68669 0.000188261 -37.2516 0.00210847 101.89 0 0 0.0168407 -17.6626 0.00210847 101.89 0.595892 1.68669 0.80674 13.493 0.593584 1.64512 1.1474 4.8713 1 S KRRFSLSVPRTET 0.00210847 101.89 _RFSLpSVPR_ RFS(0.404)LS(0.596)VPR RFS(-1.69)LS(1.69)VPR 5 2 521.26569 0.47876 371160 0 0 0 0 0 204900 166260 1064 804 89 89 4873;4874 5539;5540;5541;5542 46764 28628 Mix4_InSol_TiO2_1 5095 46766 28630 Mix4_InSol_Tio2_Reinj_1 5042 Q07002-2;Q07002 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3 1 63.4629 0.986569 18.6603 0.429332 18.66 0 0 0.948387 12.6423 0.506975 12.642 1 63.4629 0.0070831 63.463 0.999999 60.2441 0.000687749 79.836 1 S QNQRRFSMEDVSK AURORA;AURORA-A;CAMK2;CK2;PKA 0.004788 0.000687749 79.836 _RFpSMEDVSK_ RFS(1)MEDVSK RFS(63.46)MEDVS(-63.46)K 3 2 589.74921 0.52743 1108400 77721 0 0 186680 0 499730 344310 1065 804 98 98 4948 5624 47588 29049 Mix4_TiO2_Reinj_1_4 6842 47587 29048 Mix4_TiO2_1_4 6088 Q07002-2;Q07002;Q07002-3 Q07002-2 Q07002-2 >sp|Q07002-2|CDK18_HUMAN Isoform 3a of Cell division protein kinase 18 OS=Homo sapiens GN=CDK18;>sp|Q07002|CDK18_HUMAN Cell division protein kinase 18 OS=Homo sapiens GN=CDK18 PE=1 SV=3;>sp|Q07002-3|CDK18_HUMAN Isoform 3b of Cell division protein kinase 18 1 19.5725 1 43.2908 0.0618834 43.291 0 0 1 19.5725 0.402124 19.573 1 S DVSKRLSLPMDIR AURORA;AURORA-1;AURORA-A;CHK1;CK1;PKA;PKD 0.006142092 0.0618834 43.291 _RLpSLPMDIR_ RLS(1)LPMDIR RLS(19.57)LPMDIR 3 2 590.79904 -0.61066 165010 36379 0 0 128630 0 0 0 1066 805 130 130 2840 3235 27122 16959 Mix4_TiO2_Reinj_1_6 6805 27122 16959 Mix4_TiO2_Reinj_1_6 6805 Q07020 Q07020 Q07020 >sp|Q07020|RL18_HUMAN 60S ribosomal protein L18 OS=Homo sapiens GN=RPL18 PE=1 SV=2 1 64.7937 0 0 1 64.7937 0.0171259 64.794 1 S DQLALDSPKGCGT CDK1;Proline-directed 0.0057 0.0171259 64.794 _ILTFDQLALDpSPK_ ILTFDQLALDS(1)PK ILT(-64.79)FDQLALDS(64.79)PK 11 2 770.88656 0.010583 20793 0.15584 0 0 0 20793 0 0 0 1067 807 54 54 4908 5580 47092 28794 Mix4_TiO2_Reinj_1_4 3105 47092 28794 Mix4_TiO2_Reinj_1_4 3105 Q07352 Q07352 Q07352 >sp|Q07352|TISB_HUMAN Zinc finger protein 36, C3H1 type-like 1 OS=Homo sapiens GN=ZFP36L1 PE=1 SV=1 0.997892 26.7535 0 0 0.997892 26.7535 0.00586227 63.777 0.780033 6.07023 0.392411 17.59 0.368354 2.42913 0.743466 2.4291 1 S GFPRRHSVTLPSS AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.00111111 0.00586227 63.777 _RHpSVTLPSSK_ RHS(0.998)VT(0.002)LPSSK RHS(26.75)VT(-26.75)LPS(-63.78)S(-63.78)K 3 3 397.86757 0.023613 129460 0 0 0 62455 0 67003 0 1068 809 165 165 3244 3678 30681 19053 Mix4_TiO2_Reinj_1_5 8609 30680 19050 Mix4_TiO2_1_5 7798 Q07912-3;Q07912;Q07912-2 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3;>sp|Q07912-2|ACK1_HUMAN Isoform 2 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 0.5 0 0.5 0 1.65582E-25 162.11 0.5 0 7.32017E-19 155.54 1 S STFRKTSPAPGGP CAMK2;PKA;Proline-directed 0.004788 1.65582E-25 162.11 _KpTSPAPGGPAGEGPLQSLTCLIGEK_ KT(0.5)S(0.5)PAPGGPAGEGPLQSLTCLIGEK KT(0)S(0)PAPGGPAGEGPLQS(-128.9)LT(-154.9)CLIGEK 3 3 849.08378 -0.32833 918620 245850 0 0 672770 0 0 0 1069 809 886 886 3742 4221 35358 21865 Mix4_InSol_TiO2_1 5353 35358 21865 Mix4_InSol_TiO2_1 5353 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.318384 0 0.318384 0 0.00618544 73.311 0.240216 -0.607564 0.401632 36.069 1 S PLPPRLSSSPGKT PKA 0.042 0.00618544 73.311 _LpSSSPGKTMPTTQSFASDPK_ LS(0.318)S(0.318)S(0.318)PGKT(0.045)MPTTQSFASDPK LS(0)S(0)S(0)PGKT(-8.52)MPT(-36.5)T(-42.23)QS(-72.88)FAS(-73.31)DPK 2 3 716.32906 -0.21119 0 0 0 0 0 0 0 0 1070 809 887 887 3742 4221 35358 21865 Mix4_InSol_TiO2_1 5353 35358 21865 Mix4_InSol_TiO2_1 5353 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.318384 0 0.318384 0 0.00618544 73.311 0.240216 -0.607564 0.401632 36.069 1 S LPPRLSSSPGKTM CAMK2 0.042 0.00618544 73.311 _LpSSSPGKTMPTTQSFASDPK_ LS(0.318)S(0.318)S(0.318)PGKT(0.045)MPTTQSFASDPK LS(0)S(0)S(0)PGKT(-8.52)MPT(-36.5)T(-42.23)QS(-72.88)FAS(-73.31)DPK 3 3 716.32906 -0.21119 0 0 0 0 0 0 0 0 1071 809 888 888 3742 4221 35358 21865 Mix4_InSol_TiO2_1 5353 35358 21865 Mix4_InSol_TiO2_1 5353 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.318384 0 0.318384 0 0.00618544 73.311 0.240216 -0.607564 0.401632 36.069 1 S PPRLSSSPGKTMP CDK1;CDK2;NEK6;Polo box;Proline-directed 0.00405 0.00618544 73.311 _LpSSSPGKTMPTTQSFASDPK_ LS(0.318)S(0.318)S(0.318)PGKT(0.045)MPTTQSFASDPK LS(0)S(0)S(0)PGKT(-8.52)MPT(-36.5)T(-42.23)QS(-72.88)FAS(-73.31)DPK 4 3 716.32906 -0.21119 0 0 0 0 0 0 0 0 1072 809 802 802 4630 5255;5256 43883 26904 Mix4_TiO2_1_5 3836 43887 26910 Mix4_TiO2_Reinj_1_5 4262 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.999796 37.0827 0.999796 37.0827 2.97637E-07 103.66 0.999412 34.4401 8.87883E-08 113.8 1 S LQAPAGSPAPSPS GSK3;Proline-directed 0.05 8.87883E-08 113.8 _QLQAPAGpSPAPSPSPGGDDKPQVPPR_ QLQAPAGS(1)PAPSPSPGGDDKPQVPPR QLQAPAGS(37.08)PAPS(-37.08)PS(-50.9)PGGDDKPQVPPR 8 3 877.75694 0.0066108 2852200 973400 0 0 1878800 0 0 0 1073 809 806 806 4630 5255;5256 43877 26900 Mix4_TiO2_Reinj_1_5 4249 43875 26894 Mix4_TiO2_1_5 3821 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.996775 24.9001 0.983174 17.6664 1.06144E-11 121.52 0.996775 24.9001 0.000102687 93.069 2 S AGSPAPSPSPGGD CK1;Proline-directed 0.05 1.06144E-11 121.52 _QLQAPAGpSPAPpSPSPGGDDKPQVPPR_ QLQAPAGS(1)PAPS(0.997)PS(0.003)PGGDDKPQVPPR QLQAPAGS(67.86)PAPS(24.9)PS(-24.9)PGGDDKPQVPPR 12 3 904.41238 -0.43306 2406100 579120 0 0 1827000 0 0 0 1074 809 835 835 6528 7470;7471 65946 40437 Mix4_TiO2_Reinj_1_5 6118 65946 40437 Mix4_TiO2_Reinj_1_5 6118 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.732365 6.97756 0.732365 6.97756 0.0307743 75.008 2 S RPHVQLSPAPPGE Proline-directed 0.05 0.0307743 75.008 _VPIPPRPTRPHVQLpSPAPPGEEETSQWPGPApSPPR_ VPIPPRPT(0.116)RPHVQLS(0.732)PAPPGEEET(0.147)S(0.005)QWPGPAS(1)PPR VPIPPRPT(-8.01)RPHVQLS(6.98)PAPPGEEET(-6.98)S(-21.79)QWPGPAS(50.29)PPR 15 4 981.22639 -0.22393 2735600 0 0 0 2735600 0 0 0 1075 809 863 863 6535 7478 65997 40465 Mix4_TiO2_Reinj_1_5 3645 65997 40465 Mix4_TiO2_Reinj_1_5 3645 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.999956 43.5418 0.998829 29.3105 0.122017 39.076 0.999956 43.5418 0.065433 48.151 1 S PPREPLSPQGSRT ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.065433 48.151 _VPPREPLpSPQGSR_ VPPREPLS(1)PQGSR VPPREPLS(43.54)PQGS(-43.54)R 8 2 750.37195 0.12349 760970 174250 0 0 586720 0 0 0 1076 813 138 138 1813;5181 2046;5898 50154 30656 Mix4_InSol_TiO2_1 4471 50164 30672 Mix4_TiO2_Reinj_1_3 4157 Q08499-6;Q08499;Q08499-11;Q08499-9;Q08499-10;Q08499-2;Q08499-12;Q08499-7;Q07343;Q07343-3 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D PE=1 SV=2;>sp|Q08499-11|PDE4D_HUMAN Isoform 1 92.7281 0.999998 57.9426 0.00268884 128.13 0 0 1 70.2137 0.000188453 145.88 1 92.7281 0.000277495 140.78 1 74.14 0.00268884 128.13 1 S DSDYDLSPKSMSR CDK1;Proline-directed 0.0057 0.000188453 145.88 _SDSDYDLpSPK_ SDSDYDLS(1)PK S(-140.78)DS(-120.59)DY(-92.73)DLS(92.73)PK 8 2 603.73174 0.10199 3771600 740850 0 0 2152200 0 484480 394090 1077 813 651 651 1931 2183 17702 10577 Mix4_TiO2_1_3 5400 17701 10576 Mix4_TiO2_1_3 5353 Q08499-6;Q08499;Q08499-11;Q08499-9;Q08499-10;Q08499-2;Q08499-3;Q08499-4;Q08499-8;Q08499-5 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D PE=1 SV=2;>sp|Q08499-11|PDE4D_HUMAN Isoform 0.883694 8.81187 0.883694 8.81187 0.0116468 67.069 0.0518067 -12.6244 0.163004 47.395 1 S QSTIPQSPSPAPD CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0116468 67.069 _EWYQSTIPQpSPSPAPDDPEEGR_ EWYQSTIPQS(0.884)PS(0.116)PAPDDPEEGR EWY(-58.08)QS(-45.89)T(-39.18)IPQS(8.81)PS(-8.81)PAPDDPEEGR 10 3 856.03051 -0.10852 317690 317690 0 0 0 0 0 0 1078 813 653 653 1931 2183 17703 10578 Mix4_TiO2_Reinj_1_3 6034 17701 10576 Mix4_TiO2_1_3 5353 Q08499-6;Q08499;Q08499-11;Q08499-9;Q08499-10;Q08499-2;Q08499-3;Q08499-4;Q08499-8;Q08499-5 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D PE=1 SV=2;>sp|Q08499-11|PDE4D_HUMAN Isoform 0.948046 12.6244 0.551913 0.905501 0.0116468 67.069 0.948046 12.6244 0.163004 47.395 1 S TIPQSPSPAPDDP Proline-directed 0.05 0.0116468 67.069 _EWYQSTIPQSPpSPAPDDPEEGR_ EWYQSTIPQS(0.052)PS(0.948)PAPDDPEEGR EWY(-47.4)QS(-41.62)T(-41.62)IPQS(-12.62)PS(12.62)PAPDDPEEGR 12 3 856.03051 0.16891 1145000 215740 0 0 929300 0 0 0 1079 813 51 51 3228;5847 3660;6667 57658 35088 Mix4_TiO2_Reinj_1_5 5374 57657 35087 Mix4_TiO2_1_3 4644 Q08499-6;Q08499-12;Q08499-7 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499-12|PDE4D_HUMAN Isoform 12 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499-7|PDE4D_HUMAN I 0.988741 19.4268 0.931193 11.314 0.00689242 76.951 0.988741 19.4268 0.271465 29.76 3 S TARKSVSPKLSPV CDK1;GSK3;Proline-directed 0.0057 0.00689242 76.951 _SVpSPKLpSPVIpSPR_ S(0.013)VS(0.989)PKLS(0.999)PVIS(0.999)PR S(-19.43)VS(19.43)PKLS(29.76)PVIS(29.76)PR 3 2 803.85577 -1.9111 879900 240060 0 0 639840 0 0 0 1080 813 55 55 3228;3728;3729;5847 3660;4204;4205;4206;6667 35189 21778 Mix4_TiO2_Reinj_1_3 4463 35191 21779 Mix4_TiO2_1_3 3528 Q08499-6;Q08499-12;Q08499-7 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499-12|PDE4D_HUMAN Isoform 12 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499-7|PDE4D_HUMAN I 1 23.8425 1 76.9507 0.00689242 76.951 0.000419563 -33.7702 0.272521 33.77 1 23.8425 0.445729 23.843 0 0 0 0 2 S SVSPKLSPVISPR CK1;GSK3;Proline-directed 0.05 0.0749545 43.882 _LpSPVIpSPR_ LS(1)PVIS(1)PR LS(23.84)PVIS(23.84)PR 2 2 514.73251 0.19004 255330 0 0 0 255330 0 0 0 1081 813 63 63 3729 4206 35191 21779 Mix4_TiO2_1_3 3528 35191 21779 Mix4_TiO2_1_3 3528 Q08499-6;Q08499-12;Q08499-7 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499-12|PDE4D_HUMAN Isoform 12 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499-7|PDE4D_HUMAN I 0.999959 43.8824 0.999959 43.8824 0.0749545 43.882 2 S VISPRNSPRLLRR CDK1;CK1;PKA;Proline-directed 0.0057 0.0749545 43.882 _LSPVIpSPRNpSPR_ LSPVIS(1)PRNS(1)PR LS(-43.88)PVIS(43.88)PRNS(43.88)PR 10 2 741.84692 0.4275 80747 80747 0 0 0 0 0 0 1082 813 284 284 4561;5312 5180;6048 43211 26502 Mix4_TiO2_1_3 3468 51556 31552 Mix4_TiO2_1_3 7710 Q08499-6;Q08499;Q08499-11;Q08499-9;Q08499-10;Q08499-2;Q08499-3;Q08499-4;Q08499-8;Q08499-5 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D PE=1 SV=2;>sp|Q08499-11|PDE4D_HUMAN Isoform 0.870075 8.25864 0.870075 8.25864 7.25883E-08 111.51 0.714237 3.97837 0.00576067 82.241 1 S HEVEIPSPTQKEK Proline-directed 0.05 7.25883E-08 111.51 _QHEVEIPpSPTQK_ QHEVEIPS(0.87)PT(0.13)QK QHEVEIPS(8.26)PT(-8.26)QK 8 2 736.84269 0.28016 1518600 538770 0 0 979860 0 0 0 1083 816 22 22 3243;4930 3677;5606 30668 19046 Mix4_TiO2_Reinj_1_3 6520 30668 19046 Mix4_TiO2_Reinj_1_3 6520 Q09161 Q09161 Q09161 >sp|Q09161|NCBP1_HUMAN Nuclear cap-binding protein subunit 1 OS=Homo sapiens GN=NCBP1 PE=1 SV=1 0.981038 17.1391 0.971113 15.2696 5.71869E-06 102.07 0 0 0.981038 17.1391 2.93749E-11 136.76 0.49998 0 0.0535403 56.132 0.117722 -8.12538 0.14618 44.801 1 S HKRRKTSDANETE CAMK2;PKA 0.004788 2.93749E-11 136.76 _KTpSDANETEDHLESLICK_ KT(0.019)S(0.981)DANETEDHLESLICK KT(-17.14)S(17.14)DANET(-52.89)EDHLES(-130.22)LICK 3 3 723.98384 -0.16207 7998100 1233000 0 0 6503500 0 261690 0 1084 816 7 7 4906 5578 47086 28787 Mix4_TiO2_Reinj_1_3 935 47086 28787 Mix4_TiO2_Reinj_1_3 935 Q09161 Q09161 Q09161 >sp|Q09161|NCBP1_HUMAN Nuclear cap-binding protein subunit 1 OS=Homo sapiens GN=NCBP1 PE=1 SV=1 1 80.3028 1 80.3028 0.00456349 80.303 1 S MSRRRHSDENDGG CAMK2;PKA 0.004788 0.00456349 80.303 _RHpSDENDGGQPHK_ RHS(1)DENDGGQPHK RHS(80.3)DENDGGQPHK 3 2 778.81552 -0.18103 34792 0 0 0 34792 0 0 0 1085 817 176 176 903;1528 1019;1718 8594 5206 Mix4_TiO2_Reinj_1_1 5469 8594 5206 Mix4_TiO2_Reinj_1_1 5469 Q09666 Q09666 Q09666 >sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 0.5 0 0.0903322 -10.0304 0.137376 34.999 0.5 0 0.00667019 61.286 0 0 0.148404 -7.58787 0.399699 26.187 1 S AKDIDISSPEFKI CK2 0.117 0.00667019 61.286 _DIDIpSSPEFK_ DIDIS(0.5)S(0.5)PEFK DIDIS(0)S(0)PEFK 5 2 615.76813 0.058804 55478 0 0 0 55478 0 0 0 1086 817 177 177 903;1528 1019;1718 8591 5203 Mix4_TiO2_1_1 4758 8594 5206 Mix4_TiO2_Reinj_1_1 5469 Q09666 Q09666 Q09666 >sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 0.987392 18.9386 0.987392 18.9386 0.137376 34.999 0.982645 17.5298 0.00667019 61.286 0 0 0.851596 7.58787 0.399699 26.187 1 S KDIDISSPEFKIK Polo box;Proline-directed 0.00405 0.00667019 61.286 _DIDISpSPEFK_ DIDIS(0.013)S(0.987)PEFK DIDIS(-18.94)S(18.94)PEFK 6 2 615.76813 0.18416 272690 43090 0 0 148480 0 0 81122 1087 817 135 135 3510 3963 33123 20478 Mix4_TiO2_1_5 3787 33120 20475 Mix4_InSol_TiO2_1 4764 Q09666 Q09666 Q09666 >sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 1 85.8046 1 85.8046 0.00136697 85.805 0 0 1 139.505 3.25521E-13 152.97 1 91.6778 0.000753876 91.678 1 S IKPRLKSEDGVEG CAMK2 0.042 3.25521E-13 152.97 _LKpSEDGVEGDLGETQSR_ LKS(1)EDGVEGDLGETQSR LKS(85.8)EDGVEGDLGET(-85.8)QS(-85.8)R 3 2 950.42022 -0.43992 274080 31722 0 0 0 0 190130 52228 1088 817 216 216 3630 4091 34115 21056 Mix4_TiO2_Reinj_1_2 4146 34115 21056 Mix4_TiO2_Reinj_1_2 4146 Q09666 Q09666 Q09666 >sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 0.981105 19.0889 0.750926 7.58369 0.061873 54.965 0 0 0.981105 19.0889 0.000624455 91.295 0 0 0 0 1 S SGSGAASPTGSAV CK1;GSK3;Proline-directed 0.05 0.000624455 91.295 _LPSGSGAApSPTGSAVDIR_ LPSGSGAAS(0.981)PT(0.012)GS(0.007)AVDIR LPS(-43.2)GS(-43.2)GAAS(19.09)PT(-19.09)GS(-21.66)AVDIR 9 2 861.90655 0.36025 374540 23536 0 0 351000 0 0 0 1089 822 1147 1147 3489 3940 32935 20404 Mix4_TiO2_Reinj_1_1 7340 32937 20407 Mix4_TiO2_Reinj_1_5 7821 Q12769 Q12769 Q12769 >sp|Q12769|NU160_HUMAN Nuclear pore complex protein Nup160 OS=Homo sapiens GN=NUP160 PE=1 SV=3 0.347177 0 3.74046E-07 -64.2705 9.23568E-18 137.66 0 0 0.347177 0 2.30342E-45 197.78 0.118429 -8.09143 9.05204E-18 138.04 1 S WIVQPVSGAVYDR 2.30342E-45 197.78 _LIRPEYAWIVQPVpSGAVYDRPGASPK_ LIRPEYAWIVQPVS(0.347)GAVY(0.347)DRPGAS(0.306)PK LIRPEY(-61.67)AWIVQPVS(0)GAVY(0)DRPGAS(-0.55)PK 14 4 738.13102 -0.15113 0 0 0 0 0 0 0 0 1090 822 1157 1157 3489 3940 32937 20407 Mix4_TiO2_Reinj_1_5 7821 32937 20407 Mix4_TiO2_Reinj_1_5 7821 Q12769 Q12769 Q12769 >sp|Q12769|NU160_HUMAN Nuclear pore complex protein Nup160 OS=Homo sapiens GN=NUP160 PE=1 SV=3 1 76.769 1 66.284 9.23568E-18 137.66 0 0 1 76.769 2.30342E-45 197.78 0.999881 39.2622 9.05204E-18 138.04 1 S YDRPGASPKRNHD CDK1;CDK2;Proline-directed 0.0057 2.30342E-45 197.78 _LIRPEYAWIVQPVSGAVYDRPGApSPK_ LIRPEYAWIVQPVSGAVYDRPGAS(1)PK LIRPEY(-197.78)AWIVQPVS(-120.98)GAVY(-76.77)DRPGAS(76.77)PK 24 3 983.83894 -0.58854 21475000 240090 0 0 21120000 115420 0 0 1091 823 822 822 4839 5499 46264 28285 Mix4_TiO2_Reinj_1_5 5616 46264 28285 Mix4_TiO2_Reinj_1_5 5616 Q12770;Q12770-2;Q12770-4 Q12770 Q12770 >sp|Q12770|SCAP_HUMAN Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP PE=1 SV=4;>sp|Q12770-2|SCAP_HUMAN Isoform 2 of Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP 0.834394 7.02306 0 0 0.834394 7.02306 0.0712314 53.465 1 S GRQRRDSGVGSGL CAMK2;F box bTrCP;GSK3;PKA;PKA/AKT 0.000624338 0.0712314 53.465 _RDpSGVGSGLEAQESWER_ RDS(0.834)GVGS(0.166)GLEAQESWER RDS(7.02)GVGS(-7.02)GLEAQES(-53.46)WER 3 3 648.28121 -0.034264 65331 0 0 0 65331 0 0 0 1092 826 334 334 6539 7482 66049 40528 Mix4_TiO2_Reinj_1_5 7104 66048 40527 Mix4_TiO2_1_5 6274 Q12815 Q12815 Q12815 >sp|Q12815|TROAP_HUMAN Tastin OS=Homo sapiens GN=TROAP PE=1 SV=3 0.999994 53.4226 0.999958 43.9736 0.00227571 81.097 0 0 0.999994 53.4226 0.00236813 80.397 1 S RAQRVPSPGPPTL CAMK2;ERK/MAPK;Proline-directed 0.0034 0.00227571 81.097 _VPpSPGPPTLTSYSVLR_ VPS(1)PGPPTLTSYSVLR VPS(53.42)PGPPT(-53.42)LT(-60.21)S(-66.8)Y(-75.48)S(-65.1)VLR 3 2 875.9424 0.44329 167640 42009 0 0 125640 0 0 0 1093 827 72 72 6573 7523 66627 40881 Mix4_TiO2_Reinj_1_4 1818 66628 40883 Mix4_TiO2_Reinj_1_4 1862 Q12834 Q12834 Q12834 >sp|Q12834|CDC20_HUMAN Cell division cycle protein 20 homolog OS=Homo sapiens GN=CDC20 PE=1 SV=2 0.98365 18.4382 0.572375 1.36142 0.217921 30.21 0.693358 6.55356 0.671165 6.5536 0.98365 18.4382 0.0978628 39.935 0 0 0 0 1 S KVQTTPSKPGGDR 0.0978628 39.935 _VQTTPpSKPGGDR_ VQT(0.002)T(0.014)PS(0.984)KPGGDR VQT(-26.39)T(-18.44)PS(18.44)KPGGDR 6 2 661.80865 0.94537 517970 98123 35688 0 384160 0 0 0 1094 828 634 634 2118 2402 19551 11922 Mix4_TiO2_Reinj_1_5 2469 19551 11922 Mix4_TiO2_Reinj_1_5 2469 Q12852 Q12852 Q12852 >sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 OS=Homo sapiens GN=MAP3K12 PE=1 SV=2 1 79.3958 0.999998 57.0828 0.0449782 57.217 1 79.3958 6.43731E-06 109.09 1 S GAGDPGSPPPARG ERK/MAPK;Proline-directed 0.0025 6.43731E-06 109.09 _GATGGAGDPGpSPPPAR_ GATGGAGDPGS(1)PPPAR GAT(-79.4)GGAGDPGS(79.4)PPPAR 11 2 722.81446 0.3173 170610 41570 0 0 129040 0 0 0 1095 833 476 476 1250 1409 11750 7201 Mix4_TiO2_1_3 6925 11754 7205 Mix4_TiO2_Reinj_1_5 7513 Q12906;Q12906-3;Q12906-2;Q12906-5 Q12906 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3;>sp|Q12906-3|ILF3_HUMAN Isoform 3 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-2|ILF3_HUMAN Isoform DRBP76 of Interleukin enhancer- 0.340771 0 0.340771 0 0.00395131 93.943 0 0 0.323914 0 1.26225E-05 101.46 0 0 1 S GAEGRDSSKGEDS PKA 0.042 1.26225E-05 101.46 _DpSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTK_ DS(0.341)S(0.341)KGEDS(0.289)AEET(0.02)EAKPAVVAPAPVVEAVS(0.002)T(0.007)PS(0.001)AAFPSDATAEQGPILTK DS(0)S(0)KGEDS(-0.72)AEET(-12.22)EAKPAVVAPAPVVEAVS(-22.24)T(-17.04)PS(-26.94)AAFPS(-43.63)DAT(-47.15)AEQGPILT(-58.92)K 2 4 1233.8445 0.49453 0 0 0 0 0 0 0 0 0 1096 833 477 477 1250 1409 11750 7201 Mix4_TiO2_1_3 6925 11754 7205 Mix4_TiO2_Reinj_1_5 7513 Q12906;Q12906-3;Q12906-2;Q12906-5 Q12906 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3;>sp|Q12906-3|ILF3_HUMAN Isoform 3 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-2|ILF3_HUMAN Isoform DRBP76 of Interleukin enhancer- 0.340771 0 0.340771 0 0.00395131 93.943 0 0 0.323914 0 1.26225E-05 101.46 0 0 1 S AEGRDSSKGEDSA CAMK2;CK2 0.042 1.26225E-05 101.46 _DpSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTK_ DS(0.341)S(0.341)KGEDS(0.289)AEET(0.02)EAKPAVVAPAPVVEAVS(0.002)T(0.007)PS(0.001)AAFPSDATAEQGPILTK DS(0)S(0)KGEDS(-0.72)AEET(-12.22)EAKPAVVAPAPVVEAVS(-22.24)T(-17.04)PS(-26.94)AAFPS(-43.63)DAT(-47.15)AEQGPILT(-58.92)K 3 4 1233.8445 0.49453 0 0 0 0 0 0 0 0 0 1097 833 482 482 1250;2162 1409;2448 11751 7202 Mix4_TiO2_1_5 6752 19867 12127 Mix4_TiO2_1_5 6941 Q12906;Q12906-3;Q12906-2;Q12906-5 Q12906 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3;>sp|Q12906-3|ILF3_HUMAN Isoform 3 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-2|ILF3_HUMAN Isoform DRBP76 of Interleukin enhancer- 0.51139 3.87494 0.51139 3.87494 9.7843E-06 103.58 0 0 0.45998 3.85976 1.26225E-05 101.46 0 0 1 S SSKGEDSAEETEA CK2 0.117 9.7843E-06 103.58 _DSSKGEDpSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTK_ DS(0.192)S(0.075)KGEDS(0.511)AEET(0.21)EAKPAVVAPAPVVEAVS(0.004)T(0.004)PS(0.004)AAFPSDATAEQGPILTK DS(-4.25)S(-8.36)KGEDS(3.87)AEET(-3.87)EAKPAVVAPAPVVEAVS(-21.01)T(-21.01)PS(-21.01)AAFPS(-36.34)DAT(-39.23)AEQGPILT(-48.86)K 8 5 987.27706 0.22547 519060 0.1521 519060 0 0 0 0 0 0 1098 833;834 382;382 382 4992 5675;5676 48192 29457 Mix4_TiO2_Reinj_1_5 2174 48191 29456 Mix4_TiO2_Reinj_1_5 1619 Q12906;Q12906-3;Q12906-2;Q12906-5;Q12906-6;Q12906-4 Q12906;Q12906-6 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3;>sp|Q12906-3|ILF3_HUMAN Isoform 3 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-2|ILF3_HUMAN Isoform DRBP76 of Interleukin enhancer- 0.974973 15.9059 0.974973 15.9059 0.000178013 102.83 1 S EDGEEKSPSKKKK CDK1;CDK2;Proline-directed 0.0057 0.000178013 102.83 _RPMEEDGEEKpSPSK_ RPMEEDGEEKS(0.975)PS(0.025)K RPMEEDGEEKS(15.91)PS(-15.91)K 11 2 849.85567 0.45468 249900 0 0 0 249900 0 0 0 1099 833;834 384;384 384 4992 5675;5676 48189 29454 Mix4_TiO2_Reinj_1_3 1523 48191 29456 Mix4_TiO2_Reinj_1_5 1619 Q12906;Q12906-3;Q12906-2;Q12906-5;Q12906-6;Q12906-4 Q12906;Q12906-6 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3;>sp|Q12906-3|ILF3_HUMAN Isoform 3 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-2|ILF3_HUMAN Isoform DRBP76 of Interleukin enhancer- 0.980313 16.9718 0.980313 16.9718 0.000178013 102.83 1 S GEEKSPSKKKKKI 0.000178013 102.83 _RPM(ox)EEDGEEKSPpSK_ RPMEEDGEEKS(0.02)PS(0.98)K RPMEEDGEEKS(-16.97)PS(16.97)K 13 2 857.85312 0.35712 48834 0 0 0 48834 0 0 0 1100 834 476 476 1249 1406 11728 7195 Mix4_TiO2_Reinj_1_3 7246 11729 7196 Mix4_TiO2_Reinj_1_5 7203 Q12906-6;Q12906-4 Q12906-6 Q12906-6 >sp|Q12906-6|ILF3_HUMAN Isoform 6 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-4|ILF3_HUMAN Isoform ILF3-A of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 0.270545 0 0.252779 -1.81875 0.0124904 79.646 0 0 0.270545 0 0.00236984 95.222 0 0 0 0 1 S GAEGRDSSKGEDS PKA 0.042 0.00236984 95.222 _DpSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK_ DS(0.271)S(0.271)KGEDS(0.271)AEET(0.179)EAKPAVVAPAPVVEAVS(0.007)T(0.002)PSAAFPSDATAENVK DS(0)S(0)KGEDS(0)AEET(-1.79)EAKPAVVAPAPVVEAVS(-15.78)T(-21.09)PS(-36.17)AAFPS(-62.28)DAT(-62.34)AENVK 2 4 1134.7852 0.84141 0 0 0 0 0 0 0 0 0 1101 834 477 477 1249 1406 11728 7195 Mix4_TiO2_Reinj_1_3 7246 11729 7196 Mix4_TiO2_Reinj_1_5 7203 Q12906-6;Q12906-4 Q12906-6 Q12906-6 >sp|Q12906-6|ILF3_HUMAN Isoform 6 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-4|ILF3_HUMAN Isoform ILF3-A of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 0.270545 0 0.252779 -1.81875 0.0124904 79.646 0 0 0.270545 0 0.00236984 95.222 0 0 0 0 1 S AEGRDSSKGEDSA CAMK2;CK2 0.042 0.00236984 95.222 _DpSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK_ DS(0.271)S(0.271)KGEDS(0.271)AEET(0.179)EAKPAVVAPAPVVEAVS(0.007)T(0.002)PSAAFPSDATAENVK DS(0)S(0)KGEDS(0)AEET(-1.79)EAKPAVVAPAPVVEAVS(-15.78)T(-21.09)PS(-36.17)AAFPS(-62.28)DAT(-62.34)AENVK 3 4 1134.7852 0.84141 0 0 0 0 0 0 0 0 0 1102 834 482 482 1249 1406 11727 7194 Mix4_TiO2_1_5 6346 11729 7196 Mix4_TiO2_Reinj_1_5 7203 Q12906-6;Q12906-4 Q12906-6 Q12906-6 >sp|Q12906-6|ILF3_HUMAN Isoform 6 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-4|ILF3_HUMAN Isoform ILF3-A of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 0.384251 1.81875 0.384251 1.81875 0.0124904 79.646 0 0 0.270545 0 0.00236984 95.222 0 0 0 0 1 S SSKGEDSAEETEA CK2 0.117 0.00236984 95.222 _DSSKGEDpSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK_ DS(0.253)S(0.253)KGEDS(0.384)AEET(0.1)EAKPAVVAPAPVVEAVS(0.005)T(0.005)PSAAFPSDATAENVK DS(-1.82)S(-1.82)KGEDS(1.82)AEET(-5.84)EAKPAVVAPAPVVEAVS(-19.06)T(-18.78)PS(-32.52)AAFPS(-41.37)DAT(-49.23)AENVK 8 4 1134.7852 0.47174 0 0 0 0 0 0 0 0 0 1103 835 176 176 3049 3468 29100 18193 Mix4_TiO2_1_4 3471 29100 18193 Mix4_TiO2_1_4 3471 Q12982-2;Q12982 Q12982-2 Q12982-2 >sp|Q12982-2|BNIP2_HUMAN Isoform 2 of BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 OS=Homo sapiens GN=BNIP2;>sp|Q12982|BNIP2_HUMAN BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 OS=Homo sapiens GN=BNIP2 PE=1 SV=1 0.999291 31.4932 0.999291 31.4932 0.00980178 73.494 0 0 1 S EVIRKGSITEYTA AURORA;AURORA-1;AURORA-A;CAMK2;CHK1;CK2;PKA;PKD 0.004788 0.00980178 73.494 _KGpSITEYTAAEEK_ KGS(0.999)IT(0.001)EYTAAEEK KGS(31.49)IT(-31.49)EY(-73.49)T(-73.49)AAEEK 3 2 753.83981 1.5966 62250 62250 0 0 0 0 0 0 1104 836 86 86 488 553 4533 2742 Mix4_TiO2_Reinj_1_6 2026 4533 2742 Mix4_TiO2_Reinj_1_6 2026 Q12983 Q12983 Q12983 >sp|Q12983|BNIP3_HUMAN BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 OS=Homo sapiens GN=BNIP3 PE=1 SV=2 0.983156 17.6619 0.81764 7.91983 0.474169 15.115 0.983156 17.6619 0.00518127 84.321 0 0 0 0 1 S SETDTHSIGEKNS CK1;CK2 0.117 0.00518127 84.321 _ASETDTHpSIGEK_ ASETDT(0.017)HS(0.983)IGEK AS(-68.37)ET(-69.56)DT(-17.66)HS(17.66)IGEK 8 2 677.77975 0.12371 229200 22239 0 0 206960 0 0 0 1105 837 691 691 4993 5677 48193 29458 Mix4_TiO2_Reinj_1_3 1476 48193 29458 Mix4_TiO2_Reinj_1_3 1476 Q12996 Q12996 Q12996 >sp|Q12996|CSTF3_HUMAN Cleavage stimulation factor subunit 3 OS=Homo sapiens GN=CSTF3 PE=1 SV=1 1 113.083 0 0 1 113.083 0.0003911 113.08 1 S KRPNEDSDEDEEK CK2 0.117 0.0003911 113.08 _RPNEDpSDEDEEK_ RPNEDS(1)DEDEEK RPNEDS(113.08)DEDEEK 6 2 771.78322 0.1537 45197 0 0 0 45197 0 0 0 1106 838 560 560 4076;4077 4643;4644 38619 23688 Mix4_TiO2_Reinj_1_3 8954 38614 23683 Mix4_TiO2_1_3 7853 Q13042;Q13042-2;Q13042-3 Q13042 Q13042 >sp|Q13042|CDC16_HUMAN Cell division cycle protein 16 homolog OS=Homo sapiens GN=CDC16 PE=1 SV=2;>sp|Q13042-2|CDC16_HUMAN Isoform 2 of Cell division cycle protein 16 homolog OS=Homo sapiens GN=CDC16;>sp|Q13042-3|CDC16_HUMAN Isoform 3 of Cell division cycle 1 52.0902 1 5.0756 0.00100132 84.129 1 52.0902 0.00333843 71.56 1 S TLKNIISPPWDFR Proline-directed 0.05 0.00100132 84.129 _NIIpSPPWDFREFEVEK_ NIIS(1)PPWDFREFEVEK NIIS(52.09)PPWDFREFEVEK 4 2 1043.4877 0.39293 551170 108450 0 0 442720 0 0 0 1107 839 410 410 1612;1712 1809;1927 15756 9543 Mix4_TiO2_Reinj_1_4 3913 15756 9543 Mix4_TiO2_Reinj_1_4 3913 Q13043;Q13043-2 Q13043 Q13043 >sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sapiens GN=STK4 PE=1 SV=2;>sp|Q13043-2|STK4_HUMAN Isoform 2 of Serine/threonine-protein kinase 4 OS=Homo sapiens GN=STK4 1 87.181 1 80.4354 0.00296737 80.435 1 87.181 0.00132284 87.181 0 0 0 0 1 S KENQINSFGKSVP GSK3 0.081 0.00132284 87.181 _ENQINpSFGK_ ENQINS(1)FGK ENQINS(87.18)FGK 6 2 558.7397 0.21326 263590 1.3138 139300 0 0 124290 0 0 0 1108 839 320 320 1900;4531 2146;2147;2148;5146 17485 10487 Mix4_InSol_TiO2_1 5329 17435 10466 Mix4_TiO2_Reinj_1_3 3183 Q13043;Q13043-2 Q13043 Q13043 >sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sapiens GN=STK4 PE=1 SV=2;>sp|Q13043-2|STK4_HUMAN Isoform 2 of Serine/threonine-protein kinase 4 OS=Homo sapiens GN=STK4 1 82.7547 1 73.4516 1.08326E-16 140.81 1 87.7933 1.92931E-24 171.58 1 82.7547 4.56003E-11 121.98 1 78.024 6.60951E-17 147 1 S QDDEENSEEDEMD CK2 0.117 1.92931E-24 171.58 _EVDQDDEENpSEEDEMDSGTMVR_ EVDQDDEENS(1)EEDEMDSGTMVR EVDQDDEENS(82.75)EEDEMDS(-82.75)GT(-98.44)MVR 10 3 880.3142 -0.11282 20448000 907400 0 0 2263800 0 9489600 7786800 1109 839 438 438 2861 3259 27277 17045 Mix4_TiO2_Reinj_1_4 8407 27277 17045 Mix4_TiO2_Reinj_1_4 8407 Q13043 Q13043 Q13043 >sp|Q13043|STK4_HUMAN Serine/threonine-protein kinase 4 OS=Homo sapiens GN=STK4 PE=1 SV=2 0.879512 8.63331 0.603294 1.82485 0.253247 39.507 0.879512 8.63331 0.000434567 86.902 1 S DYEFLKSWTVEDL 0.000434567 86.902 _IPQDGDYEFLKpSWTVEDLQK_ IPQDGDYEFLKS(0.88)WT(0.12)VEDLQK IPQDGDY(-49.82)EFLKS(8.63)WT(-8.63)VEDLQK 12 3 831.05247 0.58357 850810 183430 0 0 667380 0 0 0 1110 840 856 856 3931 4477 37306 22934 Mix4_InSol_Tio2_Reinj_1 5274 37306 22934 Mix4_InSol_Tio2_Reinj_1 5274 Q13045 Q13045 Q13045 >sp|Q13045|FLII_HUMAN Protein flightless-1 homolog OS=Homo sapiens GN=FLII PE=1 SV=2 0.999574 33.7007 0 0 0 0 0 0 0.999574 33.7007 0.000773187 95.512 1 S AEAVLQSPGLSGK GSK3;Proline-directed 0.05 0.000773187 95.512 _NAEAVLQpSPGLSGK_ NAEAVLQS(1)PGLSGK NAEAVLQS(33.7)PGLS(-33.7)GK 8 2 725.85051 -2.7348 61407 0 0 0 0 0 0 61407 1111 841 60 60 1999 2261;2263 18174 10840 Mix4_TiO2_Reinj_1_1 7683 18174 10840 Mix4_TiO2_Reinj_1_1 7683 Q13085-4;Q13085 Q13085-4 Q13085-4 >sp|Q13085-4|ACACA_HUMAN Isoform 4 of Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA;>sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA PE=1 SV=2 0.833189 6.98519 9.79858E-10 -90.0884 8.13196E-22 165.31 5.75423E-05 -42.3993 0.00219012 77.827 0.833189 6.98519 5.52036E-05 97.357 0 0 2 S SRFIIGSVSEDNS CK2 0.117 5.52036E-05 97.357 _FIIGpSVSEDNpSEDEISNLVK_ FIIGS(0.833)VS(0.167)EDNS(1)EDEISNLVK FIIGS(6.99)VS(-6.99)EDNS(64.82)EDEIS(-64.82)NLVK 5 2 1178.0057 0.020512 188110 3.8431 0 0 0 188110 0 0 0 1112 841 66 66 1999 2261;2263 18166 10836 Mix4_TiO2_Reinj_1_1 7474 18166 10836 Mix4_TiO2_Reinj_1_1 7474 Q13085-4;Q13085 Q13085-4 Q13085-4 >sp|Q13085-4|ACACA_HUMAN Isoform 4 of Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA;>sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA PE=1 SV=2 1 79.2654 0.999999 61.2926 8.13196E-22 165.31 0.999802 38.6595 0.00219012 77.827 1 79.2654 2.64179E-32 206.39 0 0 1 S SVSEDNSEDEISN CK1;CK2 0.117 2.64179E-32 206.39 _FIIGSVSEDNpSEDEISNLVK_ FIIGSVSEDNS(1)EDEISNLVK FIIGS(-141.81)VS(-101.06)EDNS(79.27)EDEIS(-79.27)NLVK 11 2 1138.0225 -0.15476 2004300 40.947 283110 29986 0 1691200 0 0 0 1113 841 115 115 5720 6517;6518 56157 34342 Mix4_TiO2_1_1 4344 56156 34341 Mix4_InSol_TiO2_1 5958 Q13085-4;Q13085;Q13085-2 Q13085-4 Q13085-4 >sp|Q13085-4|ACACA_HUMAN Isoform 4 of Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA;>sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA PE=1 SV=2;>sp|Q13085-2|ACACA_HUMAN Isoform E5A of Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=A 0.491207 1.5965 0.491207 1.5965 0.129924 35.593 0.0213729 -16.5376 0.283677 22.853 0 0 0.467393 1.69785 0.0526551 45.122 0 0 1 S ALHIRSSMSGLHL AURORA;PKA 0.038874 0.0526551 45.122 _SpSMSGLHLVK_ S(0.34)S(0.491)MS(0.169)GLHLVK S(-1.6)S(1.6)MS(-4.64)GLHLVK 2 2 569.76995 0.45529 0 0 0 0 0 0 0 0 1114 841 117 117 5720 6517;6518 56162 34343 Mix4_TiO2_Reinj_1_1 3966 56156 34341 Mix4_InSol_TiO2_1 5958 Q13085-4;Q13085;Q13085-2 Q13085-4 Q13085-4 >sp|Q13085-4|ACACA_HUMAN Isoform 4 of Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA;>sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA PE=1 SV=2;>sp|Q13085-2|ACACA_HUMAN Isoform E5A of Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=A 0.962996 16.5376 0.168688 -4.64181 0.129924 35.593 0.962996 16.5376 0.283677 22.853 0 0 0.216454 -3.34317 0.0526551 45.122 0 0 1 S HIRSSMSGLHLVK CK1 0.081 0.0526551 45.122 _SSM(ox)pSGLHLVK_ S(0.016)S(0.021)MS(0.963)GLHLVK S(-17.9)S(-16.54)MS(16.54)GLHLVK 4 2 577.76741 -0.32119 98202 0 0 0 98202 0 0 0 1115 842 410 410 2466 2800 23184 14464 Mix4_TiO2_Reinj_1_3 2985 23183 14463 Mix4_TiO2_1_3 2417 Q13112 Q13112 Q13112 >sp|Q13112|CAF1B_HUMAN Chromatin assembly factor 1 subunit B OS=Homo sapiens GN=CHAF1B PE=1 SV=1 0.798126 5.97055 0.567799 1.18511 0.0390432 58.129 0.798126 5.97055 0.109718 47.294 1 S QTHRGSSPGPRPV CAMK2;Polo box;Proline-directed 0.00405 0.0390432 58.129 _GSpSPGPRPVEGTPASR_ GS(0.202)S(0.798)PGPRPVEGTPASR GS(-5.97)S(5.97)PGPRPVEGT(-47.29)PAS(-47.29)R 3 3 544.58943 -0.38132 111390 12011 0 0 99377 0 0 0 1116 842 428 428 6170 7045 61164 37063 Mix4_TiO2_Reinj_1_3 2687 61164 37063 Mix4_TiO2_Reinj_1_3 2687 Q13112 Q13112 Q13112 >sp|Q13112|CAF1B_HUMAN Chromatin assembly factor 1 subunit B OS=Homo sapiens GN=CHAF1B PE=1 SV=1 0.984241 18.1935 0.580296 1.42411 0.00787194 75.194 0.984241 18.1935 0.00156288 88.844 1 S SRTQDPSSPGTTP CK1 0.143 0.00156288 88.844 _TQDPpSSPGTTPPQAR_ TQDPS(0.984)S(0.015)PGT(0.001)TPPQAR T(-64.08)QDPS(18.19)S(-18.19)PGT(-31.46)T(-38.63)PPQAR 5 2 810.35669 0.15065 96917 23387 0 0 73530 0 0 0 1117 843 371 371 838;839 948;949 7896 4685 Mix4_TiO2_Reinj_1_4 7785 7896 4685 Mix4_TiO2_Reinj_1_4 7785 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.892065 9.17358 0.856401 10.7694 0.00279505 77.163 0.892065 9.17358 0.000271109 91.407 0.490796 0 0.000380007 82.769 1 S DFYLATSPPDSFL CK2;GSK3;NEK6;Proline-directed 0.05 0.000271109 91.407 _DFYLATpSPPDSFLDDHHLTR_ DFYLAT(0.108)S(0.892)PPDSFLDDHHLTR DFY(-62.06)LAT(-9.17)S(9.17)PPDS(-45.44)FLDDHHLT(-53.22)R 7 3 809.69328 0.23767 5988700 98386 0 0 5890300 0 0 0 1118 843 375 375 838;839 948;949 7902 4691 Mix4_TiO2_Reinj_1_3 7188 7896 4685 Mix4_TiO2_Reinj_1_4 7785 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.400756 0 0.0837347 -9.44528 0.00279505 77.163 0.400756 0 0.000271109 91.407 0.168806 -3.99047 0.000380007 82.769 1 S ATSPPDSFLDDHH CK1;CK2 0.117 0.000271109 91.407 _DFYLATpSPPDSFLDDHHLTRPHPER_ DFYLAT(0.198)S(0.401)PPDS(0.401)FLDDHHLTRPHPER DFY(-38.69)LAT(-3.05)S(0)PPDS(0)FLDDHHLT(-56.34)RPHPER 11 3 1015.1293 0.076334 0 0 0 0 0 0 0 0 1119 843 521 521 5139 5850 49710 30378 Mix4_InSol_TiO2_1 1471 49710 30378 Mix4_InSol_TiO2_1 1471 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.509427 2.5424 0 0 0.509427 2.5424 0.0156012 67.979 0.0414246 -13.331 0.0917979 44.079 1 S YRSCQRSDSDAEA CK1;CK2 0.117 0.0156012 67.979 _SCQRpSDSDAEAQGK_ S(0.207)CQRS(0.509)DS(0.284)DAEAQGK S(-3.91)CQRS(2.54)DS(-2.54)DAEAQGK 5 2 809.81179 0.063169 192290 0 0 0 0 0 192290 0 1120 843 523 523 5139 5850 49711 30379 Mix4_InSol_Tio2_Reinj_1 1503 49710 30378 Mix4_InSol_TiO2_1 1471 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.891992 11.2699 0 0 0.283689 -2.5424 0.0156012 67.979 0.891992 11.2699 0.0917979 44.079 1 S SCQRSDSDAEAQG CAMK2;CK2 0.042 0.0156012 67.979 _SCQRSDpSDAEAQGK_ S(0.067)CQRS(0.041)DS(0.892)DAEAQGK S(-11.27)CQRS(-13.33)DS(11.27)DAEAQGK 7 2 809.81179 -0.017421 173650 0 0 0 0 0 0 173650 1121 843 509 509 5333;5336 6074;6077 51828 31734 Mix4_InSol_Tio2_Reinj_1 3258 51827 31733 Mix4_InSol_TiO2_1 3280 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.776715 6.19555 0.0230766 -16.1013 0.00501848 84.884 0 0 0.0143881 -18.3484 0.0202391 62.178 0.24691 -4.73858 9.8339E-06 104.33 0.776715 6.19555 0.00650969 76.117 2 S TATPQRSGSVSNY CK1;GSK3 0.081 9.8339E-06 104.33 _SGTApTPQRpSGSVSNYR_ S(0.203)GT(0.285)AT(0.492)PQRS(0.777)GS(0.243)VSNYR S(-4.57)GT(-2.54)AT(2.54)PQRS(6.2)GS(-6.2)VS(-37.26)NY(-65.96)R 9 2 914.37476 0.37278 94292 0 0 0 0 0 0 94292 1122 843 511 511 5333;5336 6074;6077 51794 31706 Mix4_InSol_Tio2_Reinj_1 2740 51794 31706 Mix4_InSol_Tio2_Reinj_1 2740 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.999951 43.5341 0.999373 32.4722 0.00501848 84.884 0 0 0.997906 28.8695 0.0202391 62.178 0.993589 21.9601 0.0181316 64.744 0.999951 43.5341 0.00299902 95.945 1 S TPQRSGSVSNYRS CAMK2;PKA/AKT 0.00111111 0.00299902 95.945 _SGpSVSNYR_ SGS(1)VSNYR S(-43.53)GS(43.53)VS(-52.99)NY(-95.95)R 3 2 475.19239 0.20638 6651900 1039900 0 0 3953200 0 838140 820620 1123 843 501 501 5335;5336;5362 6076;6077;6104;6105 52127 31890 Mix4_InSol_Tio2_Reinj_1 4852 52133 31896 Mix4_TiO2_1_4 3985 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.912121 12.3872 0.999855 38.8431 1.84428E-15 146.17 0 0 0.919127 10.5565 7.62144E-10 120.92 0.996566 24.5356 1.23591E-15 149.63 0.912121 12.3872 1.43005E-15 148.55 1 S EITEAKSGTATPQ CK1 0.143 6.55076E-21 161.88 _SIDDEITEAKpSGTATPQR_ S(0.008)IDDEIT(0.027)EAKS(0.912)GT(0.053)ATPQR S(-20.5)IDDEIT(-15.27)EAKS(12.39)GT(-12.39)AT(-57.1)PQR 11 2 999.95442 0.45775 4466900 508460 0 0 2720800 0 66648 1171000 1124 843 532 532 5701 6494;6495 55882 34215 Mix4_TiO2_Reinj_1_4 7190 55880 34213 Mix4_TiO2_Reinj_1_3 7242 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.332946 1.14292 6.05086E-05 -41.3938 8.88907E-07 100.64 0.332946 1.14292 2.27979E-55 237.53 1 S EAQGKSSEVSLTS 2.27979E-55 237.53 _SpSEVSLTSSVTSLDSSPVDLTPR_ S(0.256)S(0.333)EVS(0.055)LT(0.186)S(0.139)S(0.028)VT(0.001)S(0.002)LDSSPVDLTPR S(-1.14)S(1.14)EVS(-7.79)LT(-2.53)S(-3.79)S(-10.75)VT(-24.34)S(-23.21)LDS(-57.06)S(-68.7)PVDLT(-100.3)PR 2 2 1222.5756 0.93965 0 0 0 0 0 0 0 0 1125 843 538 538 5701 6494;6495 55878 34211 Mix4_TiO2_1_3 6493 55880 34213 Mix4_TiO2_Reinj_1_3 7242 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.834059 7.98076 0.834059 7.98076 8.88907E-07 100.64 0.829645 9.19003 2.27979E-55 237.53 1 S SEVSLTSSVTSLD CK1;GSK3 0.081 2.27979E-55 237.53 _SSEVSLTpSSVTSLDSSPVDLTPR_ SSEVSLT(0.001)S(0.834)S(0.133)VT(0.027)S(0.005)LDSSPVDLTPR S(-42.2)S(-41.39)EVS(-41.39)LT(-29.3)S(7.98)S(-7.98)VT(-14.84)S(-22.59)LDS(-42.41)S(-57.97)PVDLT(-100.64)PR 8 2 1222.5756 0.13984 626300 219740 0 0 406560 0 0 0 1126 843 539 539 5701 6494;6495 55894 34217 Mix4_TiO2_Reinj_1_3 7175 55894 34217 Mix4_TiO2_Reinj_1_3 7175 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.561037 1.13748 0.132776 -7.98076 8.88907E-07 100.64 0.561037 1.13748 9.46508E-07 99.508 2 S EVSLTSSVTSLDS CK1;NEK6 0.076 9.46508E-07 99.508 _SSEVSLTSpSVTpSLDSSPVDLTPR_ SSEVS(0.002)LT(0.003)S(0.432)S(0.561)VT(0.219)S(0.782)LDSSPVDLTPR S(-34.61)S(-33.71)EVS(-23.77)LT(-22.78)S(-1.14)S(1.14)VT(-5.56)S(5.56)LDS(-49.68)S(-62.41)PVDLT(-99.51)PR 9 2 1262.5588 0.47504 1300500 0 0 0 1300500 0 0 0 1127 843 542 542 5701 6494;6495 55895 34218 Mix4_TiO2_Reinj_1_4 7119 55894 34217 Mix4_TiO2_Reinj_1_3 7175 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.804031 6.14984 0.00458917 -22.5946 8.88907E-07 100.64 0.804031 6.14984 9.46508E-07 99.508 2 S LTSSVTSLDSSPV CK1;GSK3 0.081 9.46508E-07 99.508 _SSEVSLTSpSVTpSLDSSPVDLTPR_ SSEVS(0.002)LT(0.009)S(0.444)S(0.527)VT(0.214)S(0.804)LDSSPVDLTPR S(-33.57)S(-32.97)EVS(-24.75)LT(-18.15)S(-0.76)S(0.76)VT(-6.15)S(6.15)LDS(-33.11)S(-38.94)PVDLT(-62.57)PR 12 2 1262.5588 0.52987 1300500 0 0 0 1300500 0 0 0 1128 843 545 545 5701 6494;6495 55881 34214 Mix4_TiO2_Reinj_1_3 7370 55880 34213 Mix4_TiO2_Reinj_1_3 7242 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.992741 23.3255 4.79197E-05 -42.4068 8.88907E-07 100.64 0.992741 23.3255 2.27979E-55 237.53 1 S SVTSLDSSPVDLT CK1 0.081 2.27979E-55 237.53 _SSEVSLTSSVTSLDpSSPVDLTPR_ SSEVSLTSSVTS(0.003)LDS(0.993)S(0.005)PVDLTPR S(-74.46)S(-73.67)EVS(-80.64)LT(-75.24)S(-62.53)S(-55.98)VT(-39.85)S(-25.93)LDS(23.33)S(-23.33)PVDLT(-81.96)PR 15 2 1222.5756 0.32449 1381700 0 0 0 1381700 0 0 0 1129 847 95 95 3214;5467;5468 3646;6221;6223;6224 30490 18952 Mix4_TiO2_Reinj_1_6 1584 53345 32593 Mix4_InSol_TiO2_1 2056 Q13185 Q13185 Q13185 >sp|Q13185|CBX3_HUMAN Chromobox protein homolog 3 OS=Homo sapiens GN=CBX3 PE=1 SV=4 0.983039 19.2716 0.975645 17.5967 0.250842 25.979 0 0 0.983039 19.2716 0.164524 33.367 0.499945 0 0.0672138 47.668 0.666667 0 1.00179 0 1 S TKRKSLSDSESDD CK2;GSK3 0.081 0.0672138 47.668 _KSLpSDSESDDSK_ KS(0.002)LS(0.983)DS(0.012)ES(0.003)DDS(0.001)K KS(-27.8)LS(19.27)DS(-19.27)ES(-24.87)DDS(-32.93)K 4 2 689.2745 -0.081531 150450 4.6028 11209 0 0 75183 0 64056 0 1130 848 316 316 1649;2574 1850;1851;2929 15110 9126 Mix4_TiO2_Reinj_1_4 4792 15106 9120 Mix4_TiO2_1_4 4258 Q13188 Q13188 Q13188 >sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sapiens GN=STK3 PE=1 SV=2 1 88.26 1 129.699 9.20718E-24 164.15 0 0 1 88.26 1.09826E-16 147.16 0 0 0.999999 62.913 2.83695E-06 98.645 1 93.2473 0.000159189 93.342 1 S EEEEENSDEDELD CK2 0.117 9.20718E-24 164.15 _ELEEEEENpSDEDELDSHTM(ox)VK_ ELEEEEENS(1)DEDELDSHTMVK ELEEEEENS(88.26)DEDELDS(-89.87)HT(-88.26)MVK 9 2 1301.9968 0.045531 19495000 6219700 0 0 11041000 0 1256600 977970 1131 848 385 385 3944;3945;3946 4492;4493;4494;4495 37410 22999 Mix4_TiO2_Reinj_1_3 2055 37409 22997 Mix4_TiO2_1_4 1526 Q13188 Q13188 Q13188 >sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sapiens GN=STK3 PE=1 SV=2 0.998073 27.1431 0.997696 26.3647 0.00450002 69.92 0.998073 27.1431 0.0131236 58.731 0.638108 4.69464 0.411677 37.794 0.448291 0 1.47514 16.5 1 S MKRNATSPQVQRP Proline-directed 0.05 0.00450002 69.92 _NATpSPQVQR_ NAT(0.002)S(0.998)PQVQR NAT(-27.14)S(27.14)PQVQR 4 2 540.74532 0.92714 1772400 231480 0 0 1227200 0 313740 0 1132 849 16 16 412;937 470;1056 3906 2334 Mix4_TiO2_Reinj_1_3 2883 3906 2334 Mix4_TiO2_Reinj_1_3 2883 Q13200 Q13200 Q13200 >sp|Q13200|PSMD2_HUMAN 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens GN=PSMD2 PE=1 SV=3 1 90.7333 1 75.3016 5.33035E-07 101.2 1 90.7333 3.61167E-07 111.01 1 S PVQPQQSPAAAPG Proline-directed 0.05 3.61167E-07 111.01 _APVQPQQpSPAAAPGGTDEKPSGK_ APVQPQQS(1)PAAAPGGTDEKPSGK APVQPQQS(90.73)PAAAPGGT(-90.73)DEKPS(-111.01)GK 8 3 766.69691 -0.034026 1614000 0.78049 674710 0 0 939330 0 0 0 1133 850 34 34 524 593 4913 2968 Mix4_TiO2_Reinj_1_5 5978 4913 2968 Mix4_TiO2_Reinj_1_5 5978 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.928313 11.1226 0.85957 7.86821 0.793219 8.2735 0.928313 11.1226 0.00202472 92.189 1 S GGALKASSAPAAA NEK6 0.076 0.00202472 92.189 _ApSSAPAAAAGLLR_ AS(0.928)S(0.072)APAAAAGLLR AS(11.12)S(-11.12)APAAAAGLLR 2 2 618.31083 -1.1444 39600 9394.3 0 0 30205 0 0 0 1134 850 21 21 583 667 5494 3277 Mix4_InSol_Tio2_Reinj_1 2900 5496 3280 Mix4_TiO2_1_5 2106 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.863395 8.00744 0.856764 7.76809 0.0107355 72.588 0 0 0.414184 -1.50568 0.0558905 52.608 0 0 0.439184 -1.06173 0.355717 28.39 0.863395 8.00744 0.0232687 60.718 1 S PGARATSPEAGGG CAMK2;Proline-directed 0.042 0.0107355 72.588 _ATpSPEAGGGGGALK_ AT(0.137)S(0.863)PEAGGGGGALK AT(-8.01)S(8.01)PEAGGGGGALK 3 2 626.7821 -0.74083 504460 192260 0 0 0 0 0 312200 1135 850 1018 1018 2863;3657 3261;4123 27285 17055 Mix4_TiO2_Reinj_1_1 2292 27283 17053 Mix4_TiO2_1_5 2175 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.995768 23.7624 0.990842 20.4197 0.00179428 98.903 0.973113 15.8673 0.0640783 41.34 0.995768 23.7624 0.00473244 67.262 0.719939 6.62055 0.244327 38.588 0.575412 2.49015 0.240565 38.675 1 S CRIPSASPQTQRK Proline-directed 0.05 0.00179428 98.903 _IPSApSPQTQR_ IPSAS(0.996)PQT(0.004)QR IPS(-43.48)AS(23.76)PQT(-23.76)QR 5 2 582.77408 0.98256 2443100 507670 23653 0 1356800 0 316250 238710 1136 850 923 923 3708 4181 34963 21660 Mix4_TiO2_2_2 2956 34960 21657 Mix4_TiO2_1_5 3165 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.9511 12.9126 0.900448 9.56409 0.000102797 148.31 0.9511 12.9126 0.00256441 84.921 0.887314 8.96291 0.00236541 87.136 0.411616 -1.55095 0.046744 49.601 0.891272 9.13672 0.00322557 118.91 0.907638 9.92806 0.00210317 90.055 1 S ATKLSASSEDISE CK2;NEK6 0.076 0.000102797 148.31 _LSApSSEDISER_ LSAS(0.951)S(0.049)EDISER LS(-35.58)AS(12.91)S(-12.91)EDIS(-84.92)ER 4 2 637.26902 -0.077656 3573200 731430 43496 0 1842400 0 602430 353480 1137 850 924 924 3708 4181 34966 21663 Mix4_TiO2_Reinj_2_1 2790 34960 21657 Mix4_TiO2_1_5 3165 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.588284 1.55095 0.582475 1.46689 0.000102797 148.31 0.506467 1.28798 0.00256441 84.921 0.119072 -8.69128 0.00236541 87.136 0.588284 1.55095 0.046744 49.601 0.108727 -9.13672 0.00322557 118.91 0.580231 1.42563 0.00210317 90.055 1 S TKLSASSEDISER CK1;GSK3 0.081 0.000102797 148.31 _LSASpSEDISER_ LSAS(0.412)S(0.588)EDISER LS(-38.08)AS(-1.55)S(1.55)EDIS(-48.44)ER 5 2 637.26902 -0.21499 61362 14899 6989.9 0 0 8185.8 0 31287 1138 850 292 292 4802 5452 45748 27979 Mix4_TiO2_1_5 4570 45751 27983 Mix4_TiO2_Reinj_1_1 4824 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 1 69.5127 1 69.5127 4.49679E-16 154.12 0.773285 11.3492 1.16778 11.349 1 64.3183 7.50247E-21 159.86 0.999672 35.1301 0.0804566 52.44 0.919587 10.6551 0.426394 33.17 1 S PPRRAPSPDGFSP CAMK2;Proline-directed 0.042 7.50247E-21 159.86 _RAPpSPDGFSPYSPEETNR_ RAPS(1)PDGFSPYSPEETNR RAPS(69.51)PDGFS(-69.51)PY(-116.14)S(-143.35)PEET(-154.12)NR 4 3 696.30038 0.46834 1935200 333360 56513 0 1248800 0 122280 174240 1139 850 275 275 5070 5765 49040 29963 Mix4_TiO2_1_5 3688 49040 29963 Mix4_TiO2_1_5 3688 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.999842 38.0183 0.999842 38.0183 0.110184 38.018 0 0 0.998846 29.3724 0.2112 29.372 0 0 0 0 1 S VRRKRVSPVPFQS PKA;Proline-directed 0.042 0.110184 38.018 _RVpSPVPFQSGR_ RVS(1)PVPFQSGR RVS(38.02)PVPFQS(-38.02)GR 3 2 655.32427 0.014203 356670 103760 0 0 252910 0 0 0 1140 850 266 266 6284 7180 62816 38232 Mix4_InSol_TiO2_1 2281 62817 38233 Mix4_InSol_Tio2_Reinj_1 2329 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.983429 20.7442 0.983429 20.7442 0.320879 20.744 0.842477 7.3967 0.0859914 40.089 1 S RTVKSESPGVRRK Proline-directed 0.05 0.0859914 40.089 _TVKSEpSPGVRR_ T(0.008)VKS(0.008)ES(0.983)PGVRR T(-20.74)VKS(-20.74)ES(20.74)PGVRR 6 2 648.32701 0.43929 132700 0 0 0 0 0 81354 51343 1141 851 204 204 2403 2724 22422 13978 Mix4_TiO2_Reinj_1_6 1676 22422 13978 Mix4_TiO2_Reinj_1_6 1676 Q13242 Q13242 Q13242 >sp|Q13242|SRSF9_HUMAN Serine/arginine-rich splicing factor 9 OS=Homo sapiens GN=SRSF9 PE=1 SV=1 0.990358 20.1326 0 0 0.990358 20.1326 0.00216414 96.911 1 S GSRGRDSPYQSRG GSK3;PKA;Proline-directed 0.042 0.00216414 96.911 _GRDpSPYQSR_ GRDS(0.99)PY(0.01)QSR GRDS(20.13)PY(-20.13)QS(-44.39)R 4 2 573.2404 0.15576 283860 0 0 0 283860 0 0 0 1142 851 211 211 2453 2781;2782 23040 14403 Mix4_TiO2_Reinj_1_6 6349 23040 14403 Mix4_TiO2_Reinj_1_6 6349 Q13242 Q13242 Q13242 >sp|Q13242|SRSF9_HUMAN Serine/arginine-rich splicing factor 9 OS=Homo sapiens GN=SRSF9 PE=1 SV=1 0.999995 53.0012 0.999456 37.0768 0.126788 37.592 0.999995 53.0012 0.00446039 86.908 0 0 0 0 0 0 1 S PYQSRGSPHYFSP CK1;PKA;Proline-directed 0.042 0.00446039 86.908 _GpSPHYFSPFRPY_ GS(1)PHYFSPFRPY GS(53)PHY(-71.77)FS(-53)PFRPY(-86.91) 2 2 767.82938 -0.10315 1052100 67299 0 0 984830 0 0 0 1143 851 216 216 2453 2781;2782 23051 14405 Mix4_TiO2_Reinj_1_6 6684 23051 14405 Mix4_TiO2_Reinj_1_6 6684 Q13242 Q13242 Q13242 >sp|Q13242|SRSF9_HUMAN Serine/arginine-rich splicing factor 9 OS=Homo sapiens GN=SRSF9 PE=1 SV=1 0.999291 32.4775 0.556049 2.44897 0.765604 2.449 0.999291 32.4775 0.0412839 53.415 0 0 0 0 0 0 2 S GSPHYFSPFRPY_ CDK1;CDK2;Proline-directed 0.0057 0.0412839 53.415 _GpSPHYFpSPFRPY_ GS(1)PHY(0.001)FS(0.999)PFRPY GS(53.41)PHY(-32.48)FS(32.48)PFRPY(-38.55) 7 2 807.81255 0.70862 139000 38540 0 0 100450 0 0 0 1144 852 17 17 71;72 84;86 811 550 Mix4_TiO2_1_6 4006 814 553 Mix4_TiO2_Reinj_1_5 5504 Q13263;Q13263-2 Q13263 Q13263 >sp|Q13263|TIF1B_HUMAN Transcription intermediary factor 1-beta OS=Homo sapiens GN=TRIM28 PE=1 SV=5;>sp|Q13263-2|TIF1B_HUMAN Isoform 2 of Transcription intermediary factor 1-beta OS=Homo sapiens GN=TRIM28 0.428539 0 0.428539 0 3.29744E-36 185.66 0 0 0.16556 -7.01529 1.49683E-36 190.89 0 0 0.153324 -7.04754 6.88782E-08 107.9 0.17234 -6.80539 0.000106277 92.941 1 S AAASAASGSPGPG CK1 0.081 1.49683E-36 190.89 _(ac)AASAAAASAAAASAApSGSPGPGEGSAGGEK_ AASAAAASAAAAS(0.064)AAS(0.429)GS(0.429)PGPGEGS(0.078)AGGEK AAS(-37.44)AAAAS(-30.15)AAAAS(-8.25)AAS(0)GS(0)PGPGEGS(-7.38)AGGEK 16 3 837.0328 0.71609 0 0 0 0 0 0 0 0 0 1145 852 19 19 71;72 84;86 810 549 Mix4_TiO2_1_5 4854 814 553 Mix4_TiO2_Reinj_1_5 5504 Q13263;Q13263-2 Q13263 Q13263 >sp|Q13263|TIF1B_HUMAN Transcription intermediary factor 1-beta OS=Homo sapiens GN=TRIM28 PE=1 SV=5;>sp|Q13263-2|TIF1B_HUMAN Isoform 2 of Transcription intermediary factor 1-beta OS=Homo sapiens GN=TRIM28 0.997497 28.4567 0.997497 28.4567 3.29744E-36 185.66 0 0 0.992376 21.2103 1.49683E-36 190.89 0 0 0.776899 7.04754 6.88782E-08 107.9 0.825893 6.80539 0.000106277 92.941 1 S ASAASGSPGPGEG Proline-directed 0.05 1.49683E-36 190.89 _(ac)AASAAAASAAAASAASGpSPGPGEGSAGGEK_ AASAAAASAAAASAAS(0.001)GS(0.997)PGPGEGS(0.001)AGGEK AAS(-144.47)AAAAS(-110.57)AAAAS(-68.01)AAS(-29.66)GS(28.46)PGPGEGS(-28.46)AGGEK 18 3 837.0328 1.0939 9312400 263.15 1161200 0 0 5593300 0 1228700 1329200 1146 852 26 26 71;72 84;86 823 556 Mix4_InSol_TiO2_2 4257 814 553 Mix4_TiO2_Reinj_1_5 5504 Q13263;Q13263-2 Q13263 Q13263 >sp|Q13263|TIF1B_HUMAN Transcription intermediary factor 1-beta OS=Homo sapiens GN=TRIM28 PE=1 SV=5;>sp|Q13263-2|TIF1B_HUMAN Isoform 2 of Transcription intermediary factor 1-beta OS=Homo sapiens GN=TRIM28 0.445597 0.48142 0.0782978 -7.38241 3.29744E-36 185.66 0 0 0.0876346 -10.1205 1.49683E-36 190.89 0 0 0.445597 0.48142 6.88782E-08 107.9 0.409626 0 0.000106277 92.941 1 S PGPGEGSAGGEKR 1.49683E-36 190.89 _(ac)AASAAAASAAAASAASGSPGPGEGpSAGGEKR_ AAS(0.002)AAAAS(0.002)AAAAS(0.037)AAS(0.113)GS(0.399)PGPGEGS(0.446)AGGEKR AAS(-22.55)AAAAS(-22.55)AAAAS(-10.78)AAS(-5.94)GS(-0.48)PGPGEGS(0.48)AGGEKR 25 3 889.0665 -0.0064858 0 0 0 0 0 0 0 0 0 1147 853 230 230 5743 6544 56432 34465 Mix4_TiO2_Reinj_1_3 7827 56432 34465 Mix4_TiO2_Reinj_1_3 7827 Q13283 Q13283 Q13283 >sp|Q13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens GN=G3BP1 PE=1 SV=1 0.481711 0 0.333333 0 1.08174E-15 150.53 0.481711 0 4.96046E-26 188.23 0 0 0.468078 0 1.89674E-15 145.9 1 S PEDAQKSSSPAPA 4.96046E-26 188.23 _pSSSPAPADIAQTVQEDLR_ S(0.482)S(0.482)S(0.037)PAPADIAQTVQEDLR S(0)S(0)S(-11.2)PAPADIAQT(-140.02)VQEDLR 1 3 655.63688 -0.1804 0 0 0 0 0 0 0 0 1148 853 231 231 5743 6544 56433 34466 Mix4_TiO2_Reinj_1_3 7829 56432 34465 Mix4_TiO2_Reinj_1_3 7827 Q13283 Q13283 Q13283 >sp|Q13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens GN=G3BP1 PE=1 SV=1 0.556146 1.8924 0.423584 1.67233 1.08174E-15 150.53 0.556146 1.8924 4.96046E-26 188.23 0 0 0.468078 0 1.89674E-15 145.9 1 S EDAQKSSSPAPAD 4.96046E-26 188.23 _SpSSPAPADIAQTVQEDLR_ S(0.084)S(0.556)S(0.36)PAPADIAQTVQEDLR S(-8.2)S(1.89)S(-1.89)PAPADIAQT(-115.06)VQEDLR 2 2 982.95168 -0.30621 3029000 0 0 0 3029000 0 0 0 1149 853 149 149 6773 7750 68681 42138 Mix4_TiO2_1_3 6868 68681 42138 Mix4_TiO2_1_3 6868 Q13283 Q13283 Q13283 >sp|Q13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens GN=G3BP1 PE=1 SV=1 0.999999 59.9159 0.999999 59.9159 1.41542E-07 107.28 0 0 1 S TEPQEESEEEVEE CK2 0.117 1.41542E-07 107.28 _YQDEVFGGFVTEPQEEpSEEEVEEPEER_ YQDEVFGGFVTEPQEES(1)EEEVEEPEER Y(-102.35)QDEVFGGFVT(-59.92)EPQEES(59.92)EEEVEEPEER 17 3 1099.4487 0.5376 725940 725940 0 0 0 0 0 0 1150 855 1981 1981 5412 6159 52779 32257 Mix4_TiO2_2_1 3935 52776 32254 Mix4_InSol_TiO2_1 7108 Q13315 Q13315 Q13315 >sp|Q13315|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=2 0.997797 29.2026 0.99714 25.5628 4.21416E-11 135.91 0.997797 29.2026 0.000160525 96.133 0 0 0.997333 25.7489 9.38431E-16 147.87 0.951594 13.412 0.00223333 78.446 1 S LAFEEGSQSTTIS 9.38431E-16 147.87 _SLAFEEGpSQSTTISSLSEK_ S(0.001)LAFEEGS(0.998)QS(0.001)TTISSLSEK S(-29.2)LAFEEGS(29.2)QS(-30.02)T(-49.39)T(-62.5)IS(-96.13)S(-96.13)LS(-96.13)EK 8 2 1040.9697 0.44242 414450 181820 22149 0 0 0 118880 91606 1151 855 369 369 5423 6172 52863 32306 Mix4_TiO2_Reinj_1_1 4537 52863 32306 Mix4_TiO2_Reinj_1_1 4537 Q13315 Q13315 Q13315 >sp|Q13315|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=2 0.572694 1.3097 0.572694 1.3097 0.0462745 53.357 0 0 1 S SLEISQSYTTTQR 0.0462745 53.357 _SLEISQpSYTTTQR_ SLEIS(0.424)QS(0.573)YT(0.001)T(0.001)T(0.001)QR S(-41.13)LEIS(-1.31)QS(1.31)Y(-36.35)T(-27.61)T(-26.55)T(-26.55)QR 7 2 797.36144 0.1414 55684 0 0 0 55684 0 0 0 1152 855 1883 1883 5807 6619 57252 34893 Mix4_TiO2_1_1 5402 57252 34893 Mix4_TiO2_1_1 5402 Q13315 Q13315 Q13315 >sp|Q13315|ATM_HUMAN Serine-protein kinase ATM OS=Homo sapiens GN=ATM PE=1 SV=2 0.333323 0 0.333323 0 0.134733 43.426 0 0 0.00920802 -20.2764 0.224465 38.39 0 0 0 0 1 S FSQTSRSTTPANL 0.134733 43.426 _pSTTPANLDSESEHFFR_ S(0.333)T(0.333)T(0.333)PANLDSESEHFFR S(0)T(0)T(0)PANLDS(-43.43)ES(-43.43)EHFFR 1 2 959.40437 0.49718 0 0 0 0 0 0 0 0 1153 860 95 95 2308 2611 21363 13093 Mix4_TiO2_Reinj_1_4 4861 21360 13086 Mix4_TiO2_1_4 4238 Q13425;Q13425-2 Q13425 Q13425 >sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapiens GN=SNTB2 PE=1 SV=1;>sp|Q13425-2|SNTB2_HUMAN Isoform Beta2-syntrophin28 of Beta-2-syntrophin OS=Homo sapiens GN=SNTB2 1 68.2016 1 68.4597 0.0126419 68.46 1 23.6081 0.299432 23.608 1 68.2016 0.0127847 68.202 1 S RGLGPPSPPAPPR ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0126419 68.46 _GLGPPpSPPAPPR_ GLGPPS(1)PPAPPR GLGPPS(68.2)PPAPPR 6 2 611.80264 -0.019797 703160 127290 74730 0 501140 0 0 0 1154 860 110 110 2345;2346 2654;2655 21677 13273 Mix4_TiO2_Reinj_1_4 2943 21672 13269 Mix4_TiO2_1_4 2630 Q13425;Q13425-2 Q13425 Q13425 >sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapiens GN=SNTB2 PE=1 SV=1;>sp|Q13425-2|SNTB2_HUMAN Isoform Beta2-syntrophin28 of Beta-2-syntrophin OS=Homo sapiens GN=SNTB2 1 4.39028 1 28.6474 0.0835777 43.222 1 41.3804 0.0903515 41.38 1 4.39028 0.737076 14.318 0 0 0 0 1 S AGEAGASPPVRRV Proline-directed 0.05 0.0835777 43.222 _GPAGEAGApSPPVRR_ GPAGEAGAS(1)PPVRR GPAGEAGAS(4.39)PPVRR 9 3 467.89267 -0.13302 645880 142910 26283 0 476690 0 0 0 1155 861 381 381 6233 7121 61793 37446 Mix4_TiO2_Reinj_1_5 2623 61793 37446 Mix4_TiO2_Reinj_1_5 2623 Q13428-4;Q13428-3;Q13428;Q13428-2;Q13428-5 Q13428-4 Q13428-4 >sp|Q13428-4|TCOF_HUMAN Isoform 4 of Treacle protein OS=Homo sapiens GN=TCOF1;>sp|Q13428-3|TCOF_HUMAN Isoform 3 of Treacle protein OS=Homo sapiens GN=TCOF1;>sp|Q13428|TCOF_HUMAN Treacle protein OS=Homo sapiens GN=TCOF1 PE=1 SV=3;>sp|Q13428-2|TCOF_HUMAN Iso 0.999971 50.1494 0.739675 9.30647 1.13388 9.3065 0.999971 50.1494 0.090978 50.149 0.997397 30.6045 0.445491 30.604 0.994057 27.0053 0.547982 27.005 1 S SAPAKESPRKGAA CDK1;CDK2;Proline-directed 0.0057 0.090978 50.149 _TSQVGAASAPAKEpSPR_ TSQVGAASAPAKES(1)PR T(-50.15)S(-50.15)QVGAAS(-50.15)APAKES(50.15)PR 14 2 818.88816 -0.55649 119950 10039 0 0 58538 0 25846 25531 1156 862 478 478 6722 7695 68164 41789 Mix4_TiO2_Reinj_1_5 5300 68164 41789 Mix4_TiO2_Reinj_1_5 5300 Q13433;Q13433-2 Q13433 Q13433 >sp|Q13433|S39A6_HUMAN Zinc transporter ZIP6 OS=Homo sapiens GN=SLC39A6 PE=1 SV=3;>sp|Q13433-2|S39A6_HUMAN Isoform 2 of Zinc transporter ZIP6 OS=Homo sapiens GN=SLC39A6 0.866783 8.18104 0 0 0 0 0.866783 8.18104 0.000151048 94.327 1 S KYESQLSTNEEKV CK1;CK2 0.081 0.000151048 94.327 _YESQLpSTNEEKVDTDDRTEGYLR_ YES(0.001)QLS(0.867)T(0.132)NEEKVDTDDRTEGYLR Y(-57.4)ES(-27.79)QLS(8.18)T(-8.18)NEEKVDT(-51.67)DDRT(-77.43)EGY(-77.02)LR 6 3 943.41346 -0.95438 196670 0 0 0 196670 0 0 0 1157 863 309 309 5716;5717 6513;6514 56120 34325 Mix4_TiO2_Reinj_1_5 4779 56120 34325 Mix4_TiO2_Reinj_1_5 4779 Q13435 Q13435 Q13435 >sp|Q13435|SF3B2_HUMAN Splicing factor 3B subunit 2 OS=Homo sapiens GN=SF3B2 PE=1 SV=2 0.977712 16.4243 0 0 0.977712 16.4243 4.67295E-21 158.4 0.111954 -7.24628 1.03349 21.365 0.782183 6.98657 0.143284 46.19 1 S SLGQSASETEEDT CK2 0.117 4.67295E-21 158.4 _SSLGQSApSETEEDTVSVSK_ SSLGQSAS(0.978)ET(0.022)EEDTVSVSK S(-80.66)S(-79.57)LGQS(-48.23)AS(16.42)ET(-16.42)EEDT(-84.65)VS(-126.18)VS(-145.43)K 8 2 1010.9334 0.49207 315170 0 0 0 215730 0 0 99433 1158 865 1408 1408 3093 3515 29401 18333 Mix4_TiO2_Reinj_1_1 4171 29401 18333 Mix4_TiO2_Reinj_1_1 4171 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.678104 3.23908 0 0 0.678104 3.23908 0.000427694 86.01 0 0 0 0 1 S AGLSPGSQVDSKS CK1;CK2;GSK3 0.081 0.000427694 86.01 _KKPGDASSLPDAGLSPGpSQVDSK_ KKPGDASSLPDAGLS(0.322)PGS(0.678)QVDSK KKPGDAS(-76.63)S(-80.85)LPDAGLS(-3.24)PGS(3.24)QVDS(-34.46)K 18 3 774.3722 0.84446 214480 0 0 0 214480 0 0 0 1159 865 1993 1993 3622 4082 34073 21028 Mix4_TiO2_Reinj_1_1 6852 34073 21028 Mix4_TiO2_Reinj_1_1 6852 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 1 64.7578 0 0 0 0 1 64.7578 2.14145E-18 142.91 1 S ELDPRGSDEENLD CK2;PKA 0.042 2.14145E-18 142.91 _LPELDPRGpSDEENLDSETSASTESLLEER_ LPELDPRGS(1)DEENLDSETSASTESLLEER LPELDPRGS(64.76)DEENLDS(-64.76)ET(-85.89)S(-91.14)AS(-106.51)T(-111.08)ES(-119.65)LLEER 9 3 1100.1543 0.91529 1058900 0 0 0 1058900 0 0 0 1160 865 1354 1354 5056 5750 48876 29869 Mix4_InSol_Tio2_Reinj_1 3859 48876 29869 Mix4_InSol_Tio2_Reinj_1 3859 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.885789 8.9297 0.804725 6.16072 0.0106244 60.883 0 0 0.838614 7.27672 0.0415629 51.138 0 0 0.885789 8.9297 0.00502806 74.651 1 S TEERRTSFSTSDV AURORA;AURORA-A;CAMK2;GSK3;PKA;PKA/AKT 0.00111111 0.00502806 74.651 _RTpSFSTSDVSK_ RT(0.113)S(0.886)FSTSDVSK RT(-8.93)S(8.93)FS(-33.37)T(-33.37)S(-41.67)DVS(-74.65)K 3 2 647.78738 0.38113 948660 172640 0 0 518300 0 0 257720 1161 865 1114 1114 5566;5567 6342;6343;6344 54472 33351 Mix4_TiO2_Reinj_1_1 2031 54482 33357 Mix4_TiO2_Reinj_1_1 2892 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.761801 5.04964 0.5 0 1.0706 12.53 0 0 0.761801 5.04964 0.0162409 67.334 0 0 0 0 1 S RSPLEHSSPEKEA CK2;NEK6 0.076 0.0162409 67.334 _SPLEHpSSPEK_ SPLEHS(0.762)S(0.238)PEK S(-43.53)PLEHS(5.05)S(-5.05)PEK 6 2 595.75809 0.037555 281460 0 0 0 281460 0 0 0 1162 865 1115 1115 5566;5567 6342;6343;6344 54480 33355 Mix4_TiO2_1_1 2497 54482 33357 Mix4_TiO2_Reinj_1_1 2892 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.792974 7.85564 0.792974 7.85564 0.259391 37.644 0 0 0.501116 0 0.899668 17.445 0 0 0 0 1 S SPLEHSSPEKEAP CDK1;CDK2;Polo box;Proline-directed 0.00405 0.0162409 67.334 _SPLEHSpSPEKEAPSPEK_ SPLEHS(0.13)S(0.793)PEKEAPS(0.077)PEK S(-37.64)PLEHS(-7.86)S(7.86)PEKEAPS(-10.13)PEK 7 3 643.62609 -0.022008 253460 38870 0 0 214590 0 0 0 1163 865 1290 1290 6556 7499 66318 40721 Mix4_TiO2_Reinj_1_5 3055 66317 40720 Mix4_TiO2_Reinj_1_1 2565 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.999975 46.1393 0.9998 37.4941 0.00237725 80.302 0 0 0.999975 46.1393 8.84562E-20 176.91 0 0 0.999945 43.2413 0.0189164 65.653 1 S VQEKPDSPGGSTQ ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 8.84562E-20 176.91 _VQEKPDpSPGGSTQIQR_ VQEKPDS(1)PGGSTQIQR VQEKPDS(46.14)PGGS(-46.14)T(-62.15)QIQR 7 3 602.95091 0.25032 2024500 230540 0 0 1365500 0 0 428470 1164 865 1294 1294 6556 7499 66314 40715 Mix4_TiO2_1_1 2174 66317 40720 Mix4_TiO2_Reinj_1_1 2565 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.365981 0 0.365981 0 0.00237725 80.302 0 0 0.00419558 -23.7535 8.84562E-20 176.91 0 0 4.74074E-05 -43.2413 0.0189164 65.653 1 S PDSPGGSTQIQRY CK1 0.143 8.84562E-20 176.91 _VQEKPDSPGGpSTQIQR_ VQEKPDS(0.268)PGGS(0.366)T(0.366)QIQR VQEKPDS(-1.35)PGGS(0)T(0)QIQR 11 2 903.92273 -0.0017073 0 0 0 0 0 0 0 0 1165 865 1267 1267 6605 7560;7561 67012 41131 Mix4_TiO2_Reinj_1_1 2940 67011 41130 Mix4_TiO2_1_1 2593 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.999968 44.9906 0.999935 41.8564 0.0231251 62.127 0.999968 44.9906 0.12471 44.991 0 0 2 S SPPAPGSAPETPE CK2 0.117 0.0231251 62.127 _VSPPAPGpSAPEpTPEDK_ VSPPAPGS(1)APET(1)PEDK VS(-44.99)PPAPGS(44.99)APET(44.99)PEDK 8 2 869.85227 0.22203 258750 53996 0 0 204760 0 0 0 1166 867 518 518 4450;5430 5061;6180;6181 52978 32375 Mix4_TiO2_1_3 6890 52978 32375 Mix4_TiO2_1_3 6890 Q13470;Q13470-2 Q13470 Q13470 >sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 PE=1 SV=3;>sp|Q13470-2|TNK1_HUMAN Isoform 2 of Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 0.689446 3.64204 0.689446 3.64204 3.8925E-07 110.46 0.602956 1.81447 0.00650189 79.581 0 0 1 S RPTGGGSSPPEIR CK1 0.143 3.8925E-07 110.46 _SLESVLSLGPRPTGGGpSSPPEIR_ SLESVLSLGPRPT(0.298)GGGS(0.689)S(0.012)PPEIR S(-110.46)LES(-108.93)VLS(-73.12)LGPRPT(-3.64)GGGS(3.64)S(-17.42)PPEIR 17 3 791.73184 -1.2994 435490 57444 0 0 378050 0 0 0 1167 867 519 519 4450;5430 5061;6180;6181 52981 32377 Mix4_TiO2_1_3 6954 52981 32377 Mix4_TiO2_1_3 6954 Q13470;Q13470-2 Q13470 Q13470 >sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 PE=1 SV=3;>sp|Q13470-2|TNK1_HUMAN Isoform 2 of Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 0.834459 7.1121 0.834459 7.1121 4.69113E-07 108.89 0.408706 0 0.00217238 77.877 0 0 2 S PTGGGSSPPEIRQ CK2;Polo box;Proline-directed 0.00405 4.69113E-07 108.89 _pSLESVLSLGPRPTGGGSpSPPEIR_ S(1)LESVLSLGPRPT(0.003)GGGS(0.162)S(0.834)PPEIR S(41.97)LES(-41.97)VLS(-69.99)LGPRPT(-24.05)GGGS(-7.11)S(7.11)PPEIR 18 3 818.38729 -0.33717 524430 524430 0 0 0 0 0 0 1168 867 502 502 5429;5430 6179;6180;6181 52974 32371 Mix4_TiO2_1_3 6815 52974 32371 Mix4_TiO2_1_3 6815 Q13470;Q13470-2 Q13470 Q13470 >sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 PE=1 SV=3;>sp|Q13470-2|TNK1_HUMAN Isoform 2 of Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 1 63.8033 1 63.8033 2.64617E-07 157.54 0.99999 49.9698 0.00106751 132.24 1 S MKGISRSLESVLS 2.64617E-07 157.54 _pSLESVLSLGPR_ S(1)LESVLSLGPR S(63.8)LES(-63.8)VLS(-147.18)LGPR 1 2 619.31304 0.032434 651690 167480 0 0 484210 0 0 0 1169 869 272 272 3774;5670 4264;4265;6456;6457 35856 22200 Mix4_InSol_TiO2_2 2849 55483 33982 Mix4_InSol_Tio2_Reinj_1 3905 Q13501;Q13501-2 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1;>sp|Q13501-2|SQSTM_HUMAN Isoform 2 of Sequestosome-1 OS=Homo sapiens GN=SQSTM1 0.996631 24.748 0.933442 11.937 1.2334E-08 121.01 0.481015 6.01619 0.0947839 49.565 0.973087 15.6573 0.00133498 92.096 0.996631 24.748 0.00101431 90.994 0.995867 24.5804 5.09511E-09 130.64 1 S SRLTPVSPESSST ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 5.09511E-09 130.64 _LTPVpSPESSSTEEK_ LTPVS(0.997)PES(0.003)SSTEEK LT(-53.73)PVS(24.75)PES(-24.75)S(-47.59)S(-51.28)T(-63.1)EEK 5 2 785.84783 0.23815 8401700 1558100 0 0 5987700 0 93531 762280 1170 869 275 275 3774;5670 4264;4265;6456;6457 35880 22220 Mix4_TiO2_Reinj_1_4 3471 55474 33976 Mix4_TiO2_Reinj_1_3 3434 Q13501;Q13501-2 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1;>sp|Q13501-2|SQSTM_HUMAN Isoform 2 of Sequestosome-1 OS=Homo sapiens GN=SQSTM1 0.879194 10.8707 0.587354 0 1.19301E-06 116.43 0.445586 0.912136 0.0947839 49.565 0.879194 10.8707 1.73737E-27 131.16 0.508175 1.35016 0.00101431 90.994 0.112816 -5.87038 5.09511E-09 130.64 2 S TPVSPESSSTEEK CK1 0.081 1.73737E-27 131.16 _LTPVpSPEpSSSTEEK_ LTPVS(0.993)PES(0.879)S(0.077)S(0.029)T(0.023)EEK LT(-52.35)PVS(23.95)PES(10.87)S(-10.87)S(-15.22)T(-16.27)EEK 8 2 825.831 0.51762 245190 182560 0 0 62631 0 0 0 1171 869 276 276 3774;5670 4264;4265;6456;6457 55471 33971 Mix4_InSol_TiO2_1 3733 55474 33976 Mix4_TiO2_Reinj_1_3 3434 Q13501;Q13501-2 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1;>sp|Q13501-2|SQSTM_HUMAN Isoform 2 of Sequestosome-1 OS=Homo sapiens GN=SQSTM1 0.475609 0 0.0268066 -14.6876 1.2334E-08 121.01 0.120376 -6.01619 0.0947839 49.565 0.0765767 -10.8707 1.73737E-27 131.16 0.475609 0 1.07766E-05 103.04 0.112816 -5.87038 5.09511E-09 130.64 2 S PVSPESSSTEEKS CK1;CK2 0.117 1.73737E-27 131.16 _SRLTPVpSPEpSSSTEEK_ S(0.004)RLT(0.077)PVS(0.958)PES(0.475)S(0.476)S(0.007)T(0.002)EEK S(-21.73)RLT(-10.9)PVS(13.63)PES(0)S(0)S(-18.16)T(-26.91)EEK 11 2 947.39757 0.59023 0 0 0 0 0 0 0 0 1172 869 24 24 4871 5537 46745 28618 Mix4_InSol_Tio2_Reinj_2 4924 46747 28620 Mix4_TiO2_Reinj_1_4 6223 Q13501 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1 0.935069 11.5839 0.419965 -1.40241 0.400274 42.233 0.5 0 0.000261193 87.798 0.785448 5.63584 0.00767351 73.2 0.935069 11.5839 0.255223 49.136 1 S REIRRFSFCCSPE AURORA;AURORA-A;CAMK2;GSK3;PKA 0.004788 0.000261193 87.798 _RFpSFCCSPEPEAEAEAAAGPGPCER_ RFS(0.935)FCCS(0.065)PEPEAEAEAAAGPGPCER RFS(11.58)FCCS(-11.58)PEPEAEAEAAAGPGPCER 3 3 954.71543 -0.74613 1641100 0 0 0 787550 0 814000 39523 1173 869 28 28 4871 5537 46743 28615 Mix4_InSol_TiO2_2 4995 46747 28620 Mix4_TiO2_Reinj_1_4 6223 Q13501 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1 0.602319 1.80292 0.580035 1.40241 0.400274 42.233 0.5 0 0.000261193 87.798 0.602319 1.80292 0.00767351 73.2 0.580293 1.407 0.255223 49.136 1 S RFSFCCSPEPEAE CK1;Proline-directed 0.05 0.000261193 87.798 _RFSFCCpSPEPEAEAEAAAGPGPCER_ RFS(0.398)FCCS(0.602)PEPEAEAEAAAGPGPCER RFS(-1.8)FCCS(1.8)PEPEAEAEAAAGPGPCER 7 3 954.71543 -0.74895 1739800 418630 0 0 787550 0 44406 489210 1174 869 266 266 5670 6456;6457 55484 33983 Mix4_InSol_Tio2_Reinj_1 3922 55483 33982 Mix4_InSol_Tio2_Reinj_1 3905 Q13501;Q13501-2 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1;>sp|Q13501-2|SQSTM_HUMAN Isoform 2 of Sequestosome-1 OS=Homo sapiens GN=SQSTM1 0.801866 6.07888 0.499407 0 1.2334E-08 121.01 0.0446263 -10.3257 0.0947839 49.565 0.499992 0 0.0011868 89.62 0.716941 7.90069 0.00101431 90.994 0.801866 6.07888 5.09511E-09 130.64 1 S EHGGKRSRLTPVS 5.09511E-09 130.64 _pSRLTPVSPESSSTEEK_ S(0.802)RLT(0.198)PVSPESSSTEEK S(6.08)RLT(-6.08)PVS(-33.84)PES(-56.16)S(-56.16)S(-56.16)T(-56.16)EEK 1 3 605.27869 -0.30666 844760 0 0 0 739050 0 33701 72006 1175 872 428 428 3847 4350;4354 36439 22486 Mix4_TiO2_Reinj_1_1 6658 36452 22493 Mix4_TiO2_Reinj_1_1 7726 Q13535;Q13535-3;Q13535-2 Q13535 Q13535 >sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3;>sp|Q13535-3|ATR_HUMAN Isoform 3 of Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR;>sp|Q13535-2|ATR_HUMAN Isoform 2 of Serine/threonine-protein kinase ATR 0.999423 33.7583 0.999414 33.5492 0.000215874 85.001 0 0 0.999423 33.7583 4.14688E-12 118.55 0 0 1 S SNSDGISPKRRRL CDK1;CDK2;CK1;Proline-directed 0.0057 4.14688E-12 118.55 _M(ox)ESM(ox)EIIEEIQCQTQQENLSSNSDGIpSPK_ MESMEIIEEIQCQTQQENLSSNSDGIS(0.999)PK MES(-98.69)MEIIEEIQCQT(-73.82)QQENLS(-44.93)S(-39.05)NS(-33.76)DGIS(33.76)PK 27 3 1146.4859 -0.5608 938460 0.35685 109720 0 0 828740 0 0 0 1176 872 435 435 4958;4959 5638;5639 47744 29172 Mix4_TiO2_Reinj_1_1 3060 47729 29163 Mix4_TiO2_1_1 2695 Q13535;Q13535-3;Q13535-2 Q13535 Q13535 >sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3;>sp|Q13535-3|ATR_HUMAN Isoform 3 of Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR;>sp|Q13535-2|ATR_HUMAN Isoform 2 of Serine/threonine-protein kinase ATR 0.937454 14.2814 0.890622 10.8554 0.0363378 50.525 0 0 0.937454 14.2814 0.125198 35.984 0.901575 10.0568 0.10526 37.637 0.376831 -1.60328 0.187851 30.793 1 S PKRRRLSSSLNPS CAMK2;PKA;PKA/AKT 0.00111111 0.0363378 50.525 _RLpSSSLNPSKR_ RLS(0.937)S(0.035)S(0.014)LNPS(0.014)KR RLS(14.28)S(-14.28)S(-18.33)LNPS(-18.33)KR 3 2 662.84028 -0.027355 1395500 204830 0 0 888810 0 301880 0 1177 872 436 436 4958;4959 5638;5639 47728 29161 Mix4_InSol_Tio2_Reinj_1 3968 47729 29163 Mix4_TiO2_1_1 2695 Q13535;Q13535-3;Q13535-2 Q13535 Q13535 >sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3;>sp|Q13535-3|ATR_HUMAN Isoform 3 of Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR;>sp|Q13535-2|ATR_HUMAN Isoform 2 of Serine/threonine-protein kinase ATR 0.545099 1.60328 0.128405 -8.21646 0.0363378 50.525 0 0 0.471721 0 0.125198 35.984 0.473655 0 0.10526 37.637 0.545099 1.60328 0.187851 30.793 1 S KRRRLSSSLNPSK CAMK2;PKA/AKT 0.001764 0.0363378 50.525 _RLSpSSLNPSK_ RLS(0.377)S(0.545)S(0.078)LNPSK RLS(-1.6)S(1.6)S(-8.47)LNPS(-30.79)K 4 2 584.78973 0.21071 69809 0 0 0 0 0 0 69809 1178 872 437 437 4958;4959 5638;5639 47742 29169 Mix4_InSol_Tio2_Reinj_1 3957 47729 29163 Mix4_TiO2_1_1 2695 Q13535;Q13535-3;Q13535-2 Q13535 Q13535 >sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3;>sp|Q13535-3|ATR_HUMAN Isoform 3 of Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR;>sp|Q13535-2|ATR_HUMAN Isoform 2 of Serine/threonine-protein kinase ATR 0.330775 0 0.0199992 -16.2922 0.0363378 50.525 0 0 0.0662323 -8.66997 0.125198 35.984 0.11582 -7.50821 0.10526 37.637 0.330775 0 0.187851 30.793 1 S RRRLSSSLNPSKR GSK3;NEK6 0.076 0.0363378 50.525 _RLpSSSLNPSKR_ RLS(0.331)S(0.331)S(0.331)LNPS(0.008)KR RLS(0)S(0)S(0)LNPS(-16.35)KR 5 3 442.22928 -0.41267 0 0 0 0 0 0 0 0 1179 874 421 421 2688 3061 25271 15600 Mix4_TiO2_Reinj_1_4 3982 25266 15595 Mix4_TiO2_1_3 3501 Q13547 Q13547 Q13547 >sp|Q13547|HDAC1_HUMAN Histone deacetylase 1 OS=Homo sapiens GN=HDAC1 PE=1 SV=1 1 94.0771 1 24.4081 0.000112863 96.972 1 94.0771 0.000282332 94.077 2 S ACEEEFSDSEEEG CK2 0.117 0.000112863 96.972 _IACEEEFpSDpSEEEGEGGRK_ IACEEEFS(1)DS(1)EEEGEGGRK IACEEEFS(94.08)DS(94.08)EEEGEGGRK 8 2 1159.4138 0.48506 1221400 209870 0 0 1011600 0 0 0 1180 874 423 423 2688 3061 25271 15600 Mix4_TiO2_Reinj_1_4 3982 25266 15595 Mix4_TiO2_1_3 3501 Q13547 Q13547 Q13547 >sp|Q13547|HDAC1_HUMAN Histone deacetylase 1 OS=Homo sapiens GN=HDAC1 PE=1 SV=1 1 94.0771 1 24.4081 0.000112863 96.972 1 94.0771 0.000282332 94.077 2 S EEEFSDSEEEGEG CK2 0.117 0.000112863 96.972 _IACEEEFpSDpSEEEGEGGRK_ IACEEEFS(1)DS(1)EEEGEGGRK IACEEEFS(94.08)DS(94.08)EEEGEGGRK 10 2 1159.4138 0.48506 1221400 209870 0 0 1011600 0 0 0 1181 875;876;877;878 311;311;311;311 311 2099 2376;2377 19209 11669 Mix4_TiO2_Reinj_1_4 7242 19209 11669 Mix4_TiO2_Reinj_1_4 7242 Q13555-4;Q13555-6;Q13555-7;Q13555-3;Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-4;Q13555-6;Q13555-7;Q13555-9 Q13555-9 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAM 1 76.2394 1 77.6231 0.00261407 111.05 0.999919 41.0596 0.00727567 69.122 1 76.2394 0.00239351 124.05 1 71.2553 0.00176391 93.832 0.999999 61.2856 0.00176391 93.832 1 S LTTMLVSRNFSAA;LTTMLVSRNFSVG CK1;GSK3 0.081 0.00239351 124.05 _GAILTTMLVpSR_ GAILTTMLVS(1)R GAILT(-101.47)T(-76.24)MLVS(76.24)R 10 2 621.31981 -0.040536 4190800 889410 64430 0 3034800 0 115340 86824 1182 875 381 381 2474;2476 2811;2813 23241 14489 Mix4_TiO2_1_4 2764 23241 14489 Mix4_TiO2_1_4 2764 Q13555-4 Q13555-4 Q13555-4 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.499906 0 0.499906 0 1.6626E-20 191.78 0 0 0.156578 -6.42127 9.04602E-20 176.5 0 0 0.424963 0 0.00327354 78.056 0.251955 -2.05972 0.0181031 64.951 1 S TDGIKGSTESCNT 1.6626E-20 191.78 _GpSTESCNTTTEDEDLK_ GS(0.5)T(0.5)ESCNTTTEDEDLK GS(0)T(0)ES(-34.25)CNT(-87.94)T(-95.61)T(-126.58)EDEDLK 2 2 933.85098 -0.035752 241270 0.10742 241270 0 0 0 0 0 0 1183 875 384 384 2474;2476 2811;2813 23269 14506 Mix4_TiO2_1_4 3520 23241 14489 Mix4_TiO2_1_4 2764 Q13555-4 Q13555-4 Q13555-4 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.965985 16.9488 0.965985 16.9488 1.6626E-20 191.78 0 0 0.686844 6.42127 9.04602E-20 176.5 0 0 0.333149 0 0.00327354 78.056 0.0621303 -8.13992 0.0181031 64.951 1 S IKGSTESCNTTTE CK1 0.081 1.6626E-20 191.78 _GSTEpSCNTTTEDEDLKVR_ GS(0.006)T(0.006)ES(0.966)CNT(0.02)T(0.003)TEDEDLKVR GS(-22.33)T(-22.33)ES(16.95)CNT(-16.95)T(-24.94)T(-39.1)EDEDLKVR 5 3 707.95958 -0.59013 1438200 0.64035 784830 0 0 653350 0 0 0 1184 875;877;878 315;315;315 315 4027;4029;4030 4586;4589;4590;4591;4592 38039 23362 Mix4_TiO2_Reinj_1_3 2558 38067 23379 Mix4_InSol_TiO2_1 5964 Q13555-4;Q13555-7;Q13555-3;Q13555-9;Q13555-8;Q13555-2;Q13555;Q13554-5;Q13554-3;Q13554-4 Q13555-4;Q13555-7;Q13555-9 Q13555-9 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 1 52.9451 1 24.0723 0.00154651 129.28 0 0 1 52.9451 0.000677339 134.65 1 55.6781 0.000190391 141.19 1 55.6781 0.0075992 68.326 1 S LVSRNFSAAKSLL CAMK2;CHK1;CK1;GSK3;PKD 0.020748 0.000190391 141.19 _NFpSAAK_ NFS(1)AAK NFS(52.95)AAK 3 2 359.152 0.0077191 1376100 0 0 0 467160 0 462080 446900 1185 875;877;878 319;319;319 319 4029;4030 4589;4590;4591;4592 38071 23383 Mix4_TiO2_Reinj_1_4 5471 38067 23379 Mix4_InSol_TiO2_1 5964 Q13555-4;Q13555-7;Q13555-3;Q13555-9;Q13555-8;Q13555-2;Q13555;Q13554-5;Q13554-3;Q13554-4 Q13555-4;Q13555-7;Q13555-9 Q13555-9 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 1 83.4756 0.999998 58.0774 0.0014558 100.11 0 0 1 83.4756 0.000677339 134.65 1 93.6398 0.000190391 141.19 1 65.0904 0.0075992 68.326 1 S NFSAAKSLLNKKS CK1 0.143 0.000190391 141.19 _NFSAAKpSLLNK_ NFSAAKS(1)LLNK NFS(-83.48)AAKS(83.48)LLNK 7 2 636.82103 0.14164 4089200 183370 0 0 407520 0 2523500 974790 1186 876;877 402;347 2474;2475 2811;2812 23241 14489 Mix4_TiO2_1_4 2764 23241 14489 Mix4_TiO2_1_4 2764 Q13555-6;Q13555-7;Q13555-3 Q13555-6;Q13555-7 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.499906 0 0.499906 0 1.6626E-20 191.78 0 0 0.156578 -6.42127 9.04602E-20 176.5 0.000264699 -34.4032 0.127218 49.261 0 0 1 S TDGIKGSTESCNT 1.6626E-20 191.78 _GpSTESCNTTTEDEDLK_ GS(0.5)T(0.5)ESCNTTTEDEDLK GS(0)T(0)ES(-34.25)CNT(-87.94)T(-95.61)T(-126.58)EDEDLK 2 2 933.85098 -0.035752 241270 0.1768 241270 0 0 0 0 0 0 1187 876;877 405;350 2474;2475 2811;2812 23245 14495 Mix4_TiO2_Reinj_1_4 3365 23241 14489 Mix4_TiO2_1_4 2764 Q13555-6;Q13555-7;Q13555-3 Q13555-6;Q13555-7 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.686844 6.42127 0.00188117 -24.2372 1.6626E-20 191.78 0 0 0.686844 6.42127 9.04602E-20 176.5 0.0816117 -9.51324 0.127218 49.261 0 0 1 S IKGSTESCNTTTE CK1 0.081 1.6626E-20 191.78 _GSTEpSCNTTTEDEDLK_ GS(0.157)T(0.157)ES(0.687)CNTTTEDEDLK GS(-6.42)T(-6.42)ES(6.42)CNT(-81.86)T(-95.38)T(-111.3)EDEDLK 5 2 933.85098 -0.17353 653350 0.47879 0 0 0 653350 0 0 0 1188 876 320 320 4034;4739 4596;5384;5385 45187 27643 Mix4_InSol_TiO2_1 5766 45195 27657 Mix4_TiO2_1_3 4531 Q13555-6 Q13555-6 Q13555-6 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.883732 8.80862 0.512474 0 0.00520793 74.081 0.560768 1.0609 0.000385095 85.513 0.531909 0.572467 1.60866E-16 142.74 0 0 0.883732 8.80862 2.97809E-08 117.5 0.6476 0 0.00648892 75.187 1 S FSVGRQSSAPASP PKA 0.042 9.72881E-24 163.45 _QpSSAPASPAASAAGLAGQAAK_ QS(0.884)S(0.116)APASPAASAAGLAGQAAK QS(8.81)S(-8.81)APAS(-73)PAAS(-91.67)AAGLAGQAAK 2 2 946.44911 -0.22242 10022000 795370 77994 0 5232700 0 1829900 2086200 1189 876 321 321 4034;4739 4596;5384;5385 45196 27661 Mix4_TiO2_1_3 4616 45195 27657 Mix4_TiO2_1_3 4531 Q13555-6 Q13555-6 Q13555-6 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.96504 14.5746 0.96504 14.5746 9.72881E-24 163.45 0.439231 -1.0609 0.000385095 85.513 0.94968 15.0958 1.60866E-16 142.74 0 0 0.76309 5.72581 2.97809E-08 117.5 0.790668 5.86865 2.21052E-07 113.72 1 S SVGRQSSAPASPA CAMK2;CHK1;GSK3;PKD 0.020748 9.72881E-24 163.45 _QSpSAPASPAASAAGLAGQAAK_ QS(0.034)S(0.965)APAS(0.001)PAASAAGLAGQAAK QS(-14.57)S(14.57)APAS(-28.76)PAAS(-46.99)AAGLAGQAAK 3 3 631.30183 0.32445 13694000 3209200 0 0 6533600 0 961300 2989700 1190 876 325 325 4034;4739 4596;5384;5385 45243 27684 Mix4_TiO2_1_4 4614 38145 23415 Mix4_InSol_TiO2_1 6483 Q13555-6 Q13555-6 Q13555-6 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.999771 36.5968 0.999771 36.5968 0.00520793 74.081 1.18227E-06 -56.7607 0.000385095 85.513 0.0700451 -8.20958 1.60866E-16 142.74 0 0 0.128855 -9.03426 2.40058E-07 99.749 0.0953179 -10.6651 0.00648892 75.187 2 S QSSAPASPAASAA CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 2.40058E-07 99.749 _QSpSAPApSPAASAAGLAGQAAK_ QS(0.438)S(0.562)APAS(1)PAASAAGLAGQAAK QS(-1.08)S(1.08)APAS(36.6)PAAS(-40.24)AAGLAGQAAK 7 2 986.43228 0.044669 78464 78464 0 0 0 0 0 0 1191 876;877;878 449;394;403 403 5892 6720;6721 58121 35298 Mix4_InSol_TiO2_1 4634 58125 35300 Mix4_InSol_TiO2_1 5437 Q13555-6;Q13555-7;Q13555-3;Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-6;Q13555-7;Q13555-9 Q13555-9 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.974477 15.9196 0.974477 15.9196 5.27827E-10 118.82 0.945121 13.0354 0.00105947 80.779 1 S GMQPQPSLCSSAM GSK3 0.081 5.27827E-10 118.82 _TAPSAGMQPQPpSLCSSAM(ox)R_ TAPSAGMQPQPS(0.974)LCS(0.025)S(0.001)AMR T(-86.81)APS(-80)AGMQPQPS(15.92)LCS(-15.92)S(-32.19)AMR 12 2 1036.9336 -0.58807 271310 0 0 0 0 0 145040 126270 1192 878 356 356 2474;2475;4309 2811;2812;4902 23241 14489 Mix4_TiO2_1_4 2764 23241 14489 Mix4_TiO2_1_4 2764 Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-9 Q13555-9 >sp|Q13555-9|KCC2G_HUMAN Isoform gamma D of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-8|KCC2G_HUMAN Isoform gamma E of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sa 0.499906 0 0.499906 0 1.6626E-20 191.78 0 0 0.156578 -6.42127 9.04602E-20 176.5 0.000264699 -34.4032 0.127218 49.261 0 0 1 S TDGIKGSTESCNT 1.6626E-20 191.78 _GpSTESCNTTTEDEDLK_ GS(0.5)T(0.5)ESCNTTTEDEDLK GS(0)T(0)ES(-34.25)CNT(-87.94)T(-95.61)T(-126.58)EDEDLK 2 2 933.85098 -0.035752 241270 0.1768 241270 0 0 0 0 0 0 1193 878 359 359 2474;2475;4309 2811;2812;4902 23245 14495 Mix4_TiO2_Reinj_1_4 3365 23241 14489 Mix4_TiO2_1_4 2764 Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-9 Q13555-9 >sp|Q13555-9|KCC2G_HUMAN Isoform gamma D of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-8|KCC2G_HUMAN Isoform gamma E of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sa 0.686844 6.42127 0.105171 -6.14801 1.6626E-20 191.78 0 0 0.686844 6.42127 9.04602E-20 176.5 0.0816117 -9.51324 0.127218 49.261 0 0 1 S IKGSTESCNTTTE CK1 0.081 1.6626E-20 191.78 _GSTEpSCNTTTEDEDLK_ GS(0.157)T(0.157)ES(0.687)CNTTTEDEDLK GS(-6.42)T(-6.42)ES(6.42)CNT(-81.86)T(-95.38)T(-111.3)EDEDLK 5 2 933.85098 -0.17353 653350 0.47879 0 0 0 653350 0 0 0 1194 879 330 330 1841;1842;3144 2078;2080;2081;3569;3570 29846 18576 Mix4_InSol_TiO2_1 4092 16851 10146 Mix4_TiO2_Reinj_1_4 3512 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 0.983033 17.6307 0.874808 8.48847 5.97586E-20 182.85 0.00130144 -28.3219 0.0255549 60.202 0.891021 9.12576 2.17703E-33 222.33 0.485526 0 1.05743 26.128 0.983033 17.6307 7.50688E-17 145.68 0.440126 0 1.39115E-10 134.36 1 S PDGVKESTESSNT GSK3 0.081 2.17703E-33 222.33 _KPDGVKEpSTESSNTTIEDEDVK_ KPDGVKES(0.983)T(0.017)ESSNTTIEDEDVK KPDGVKES(17.63)T(-17.63)ES(-53.4)S(-68.96)NT(-102.61)T(-104.2)IEDEDVK 8 3 830.03733 0.031755 18704000 1.8335 279540 0 0 18167000 0 256980 0 1195 879 333 333 1841;1842;3144 2078;2080;2081;3569;3570 16910 10178 Mix4_TiO2_1_4 3013 16911 10181 Mix4_TiO2_Reinj_1_4 3430 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 0.817423 11.1553 0.817423 11.1553 9.79049E-09 124.39 0.0115793 -18.8293 0.0255549 60.202 0.149987 -6.90605 2.17703E-33 222.33 0.0605589 -7.96326 1.05743 26.128 0.438365 0 7.50688E-17 145.68 0.0662353 -8.22487 1.39115E-10 134.36 2 S VKESTESSNTTIE CK1 0.081 8.64559E-26 202.29 _ESTEpSSNpTTIEDEDVK_ ES(0.063)T(0.063)ES(0.817)S(0.054)NT(0.942)T(0.06)IEDEDVK ES(-11.16)T(-11.16)ES(11.16)S(-13.95)NT(13.95)T(-13.95)IEDEDVK 5 2 972.35576 1.073 152740 0.014974 152740 0 0 0 0 0 0 1196 879 334 334 1841;1842;3144 2078;2080;2081;3569;3570 16852 10147 Mix4_TiO2_Reinj_1_4 3669 16851 10146 Mix4_TiO2_Reinj_1_4 3512 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 0.980872 17.9139 0.322813 -0.895457 9.79049E-09 124.39 0.263683 -1.96936 0.0255549 60.202 0.980872 17.9139 2.17703E-33 222.33 0.0605589 -7.96326 1.05743 26.128 0.438365 0 7.50688E-17 145.68 0.050418 -9.40991 1.39115E-10 134.36 1 S KESTESSNTTIED CK1 0.143 2.17703E-33 222.33 _ESTESpSNTTIEDEDVK_ ESTES(0.001)S(0.981)NT(0.016)T(0.002)IEDEDVK ES(-87.29)T(-87.29)ES(-29.09)S(17.91)NT(-17.91)T(-26.77)IEDEDVK 6 2 932.3726 0.50132 769320 0.075418 0 0 0 769320 0 0 0 1197 879 315 315 4027;4028 4586;4587;4588 38039 23362 Mix4_TiO2_Reinj_1_3 2558 38041 23363 Mix4_InSol_TiO2_1 6092 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 1 52.9451 1 3.56775 0.000796896 79.398 0 0 1 52.9451 0.00138209 91.341 1 55.6781 0.00177381 98.76 1 55.6781 0.00836893 59.785 1 S LATRNFSAAKSLL CAMK2;CK1;GSK3 0.042 0.00177381 98.76 _NFpSAAK_ NFS(1)AAK NFS(52.95)AAK 3 2 359.152 0.0077191 1068200 0 0 0 159180 0 462080 446900 1198 879 319 319 4028 4587;4588 38041 23363 Mix4_InSol_TiO2_1 6092 38041 23363 Mix4_InSol_TiO2_1 6092 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 1 81.8692 0.985455 18.3092 0.305272 18.309 0.999988 49.0805 0.00138209 91.341 1 81.8692 0.00177381 98.76 0.999999 59.7853 0.00836893 59.785 1 S NFSAAKSLLKKPD CK1 0.143 0.00177381 98.76 _NFSAAKpSLLK_ NFSAAKS(1)LLK NFS(-81.87)AAKS(81.87)LLK 7 2 579.79956 0.30643 2025300 0 0 0 1324000 0 432970 268370 1199 879 472 472 5328 6068 51759 31692 Mix4_TiO2_Reinj_1_4 3837 51758 31691 Mix4_TiO2_1_4 3079 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 0.978576 19.292 0.918891 10.7219 0.00754425 62.31 0.978576 19.292 0.0597941 43.952 0.700514 6.70071 0.786008 6.7007 0.868596 10.5467 0.045752 48.399 1 S HFHRSGSPTVPIK CAMK2;PKA/AKT;Proline-directed 0.00111111 0.00754425 62.31 _SGpSPTVPIK_ S(0.01)GS(0.979)PT(0.012)VPIK S(-19.95)GS(19.29)PT(-19.29)VPIK 3 2 483.23881 -0.14209 2336500 343700 0 0 1397600 0 27717 567520 1200 883 50 50 1619;3649 1817;1818;4115 14897 9028 Mix4_TiO2_1_3 2699 14897 9028 Mix4_TiO2_1_3 2699 Q13610 Q13610 Q13610 >sp|Q13610|PWP1_HUMAN Periodic tryptophan protein 1 homolog OS=Homo sapiens GN=PWP1 PE=1 SV=1 1 87.2853 1 87.2853 7.85001E-27 174.65 0 0 0.999999 60.9277 3.5802E-18 151.14 0.999884 39.3506 5.81708E-18 140.02 1 S QEEGGGSDEEETG CK2 0.117 7.85001E-27 174.65 _EKLQEEGGGpSDEEETGSPSEDGM(ox)QSAR_ EKLQEEGGGS(1)DEEETGSPSEDGMQSAR EKLQEEGGGS(87.29)DEEET(-87.29)GS(-130.48)PS(-161.92)EDGMQS(-174.65)AR 10 3 979.05215 -0.47039 1410900 256040 0 0 0 0 488780 666090 1201 884 652 652 2468 2802 23189 14466 Mix4_TiO2_1_3 2587 23189 14466 Mix4_TiO2_1_3 2587 Q13613 Q13613 Q13613 >sp|Q13613|MTMR1_HUMAN Myotubularin-related protein 1 OS=Homo sapiens GN=MTMR1 PE=1 SV=4 0.49687 0 0.49687 0 0.0680677 52.471 0.298902 -1.14087 0.611081 21.584 0 0 0 0 1 S SSSERGSSPSHSA CK1;PKA 0.042 0.0680677 52.471 _GpSSPSHSATSVHTSV_ GS(0.497)S(0.497)PS(0.006)HSATSVHTSV GS(0)S(0)PS(-19.22)HS(-46.11)AT(-33.14)S(-39.72)VHT(-52.47)S(-52.47)V 2 2 760.82248 0.70673 0 0 0 0 0 0 0 0 1202 884 653 653 2468 2802 23189 14466 Mix4_TiO2_1_3 2587 23189 14466 Mix4_TiO2_1_3 2587 Q13613 Q13613 Q13613 >sp|Q13613|MTMR1_HUMAN Myotubularin-related protein 1 OS=Homo sapiens GN=MTMR1 PE=1 SV=4 0.49687 0 0.49687 0 0.0680677 52.471 0.298902 -1.14087 0.611081 21.584 0 0 0 0 1 S SSERGSSPSHSAT CAMK2;GSK3;Polo box;Proline-directed 0.00405 0.0680677 52.471 _GpSSPSHSATSVHTSV_ GS(0.497)S(0.497)PS(0.006)HSATSVHTSV GS(0)S(0)PS(-19.22)HS(-46.11)AT(-33.14)S(-39.72)VHT(-52.47)S(-52.47)V 3 2 760.82248 0.70673 0 0 0 0 0 0 0 0 1203 884 655 655 2468 2802 23190 14467 Mix4_TiO2_Reinj_1_3 3241 23189 14466 Mix4_TiO2_1_3 2587 Q13613 Q13613 Q13613 >sp|Q13613|MTMR1_HUMAN Myotubularin-related protein 1 OS=Homo sapiens GN=MTMR1 PE=1 SV=4 0.388701 1.14087 0.00594883 -19.2181 0.0680677 52.471 0.388701 1.14087 0.611081 21.584 0 0 0 0 1 S ERGSSPSHSATSV CK1 0.081 0.0680677 52.471 _GSSPpSHSATSVHTSV_ GS(0.299)S(0.299)PS(0.389)HS(0.003)AT(0.003)S(0.003)VHT(0.003)S(0.003)V GS(-1.14)S(-1.14)PS(1.14)HS(-21.58)AT(-21.58)S(-21.58)VHT(-21.58)S(-21.58)V 5 2 760.82248 0.92693 0 0 0 0 0 0 0 0 1204 885 633 633 4824 5474 46056 28161 Mix4_TiO2_Reinj_1_5 2604 46056 28161 Mix4_TiO2_Reinj_1_5 2604 Q13615;Q13615-2;Q13615-3 Q13615 Q13615 >sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3 PE=1 SV=3;>sp|Q13615-2|MTMR3_HUMAN Isoform FYVE-DSP1a of Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3;>sp|Q13615-3|MTMR3_HUMAN Isoform FYVE-DSP1c of Myotubularin-rela 0.999922 41.0565 0 0 0.999922 41.0565 0.0475007 46.829 1 S LASRRCSDPSLNE CAMK2;CK1;PKA 0.004788 0.0475007 46.829 _RCpSDPSLNEK_ RCS(1)DPSLNEK RCS(41.06)DPS(-41.06)LNEK 3 2 643.26576 -0.073303 113800 0 0 0 113800 0 0 0 1205 885 647 647 5424 6173 52866 32308 Mix4_TiO2_Reinj_1_5 7576 52866 32308 Mix4_TiO2_Reinj_1_5 7576 Q13615;Q13615-2;Q13615-3 Q13615 Q13615 >sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3 PE=1 SV=3;>sp|Q13615-2|MTMR3_HUMAN Isoform FYVE-DSP1a of Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3;>sp|Q13615-3|MTMR3_HUMAN Isoform FYVE-DSP1c of Myotubularin-rela 1 67.3718 0.994185 29.319 1.18744 29.319 1 67.3718 0.000277063 87.126 1 S WQEHRRSLELSSL AURORA;AURORA-1;GSK3;PKA 0.020748 0.000277063 87.126 _pSLELSSLAGPGEDPLSADSLGKPTR_ S(1)LELSSLAGPGEDPLSADSLGKPTR S(67.37)LELS(-67.37)S(-79.26)LAGPGEDPLS(-87.13)ADS(-87.13)LGKPT(-87.13)R 1 3 859.75297 0.0044577 560130 165610 0 0 394510 0 0 0 1206 885 613 613 6202 7084 61467 37257 Mix4_TiO2_1_5 4875 61468 37258 Mix4_TiO2_Reinj_1_5 5592 Q13615;Q13615-2;Q13615-3 Q13615 Q13615 >sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3 PE=1 SV=3;>sp|Q13615-2|MTMR3_HUMAN Isoform FYVE-DSP1a of Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3;>sp|Q13615-3|MTMR3_HUMAN Isoform FYVE-DSP1c of Myotubularin-rela 0.431467 0 0.431467 0 0.00993202 69.053 0.280956 0 0.00522258 74.405 1 S RLPKTRSYDNLTT CHK1;PKD 0.020748 0.00522258 74.405 _TRpSYDNLTTACDNTVPLASR_ T(0.132)RS(0.431)Y(0.431)DNLT(0.002)T(0.002)ACDNTVPLASR T(-5.13)RS(0)Y(0)DNLT(-22.64)T(-22.64)ACDNT(-61)VPLAS(-69.05)R 3 3 779.01766 1.3424 0 0 0 0 0 0 0 0 1207 886 10 10 3048 3467 29094 18191 Mix4_TiO2_1_3 4682 29094 18191 Mix4_TiO2_1_3 4682 Q13619 Q13619 Q13619 >sp|Q13619|CUL4A_HUMAN Cullin-4A OS=Homo sapiens GN=CUL4A PE=1 SV=3 0.996363 24.3762 0.996363 24.3762 0.146679 34.205 0 0 0.881676 8.72235 0.598523 8.7223 0 0 0 0 1 S EAPRKGSFSALVG AURORA;AURORA-A;CAMK2;PKA 0.004788 0.146679 34.205 _KGpSFSALVGR_ KGS(0.996)FS(0.004)ALVGR KGS(24.38)FS(-24.38)ALVGR 3 2 551.27626 -0.13074 254190 48080 0 0 206110 0 0 0 1208 888 698 698 2862 3260 27279 17047 Mix4_TiO2_Reinj_1_5 4006 27279 17047 Mix4_TiO2_Reinj_1_5 4006 Q13625;Q13625-2 Q13625 Q13625 >sp|Q13625|ASPP2_HUMAN Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens GN=TP53BP2 PE=1 SV=2;>sp|Q13625-2|ASPP2_HUMAN Isoform Bbp of Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens GN=TP53BP2 0.987736 19.0601 0.873648 8.39755 0.648376 11.316 0.987736 19.0601 0.0893854 39.517 1 S RIPRPLSPTKLLP CAMK2;CDK1;CDK2;CHK1;ERK/MAPK;PKD;Proline-directed;WW GroupIV 0.0023175 0.0893854 39.517 _IPRPLpSPTK_ IPRPLS(0.988)PT(0.012)K IPRPLS(19.06)PT(-19.06)K 6 2 544.79682 0.20278 343640 62426 0 0 281220 0 0 0 1209 888 480 480 3137 3562 29812 18561 Mix4_TiO2_Reinj_1_5 4047 29812 18561 Mix4_TiO2_Reinj_1_5 4047 Q13625;Q13625-2 Q13625 Q13625 >sp|Q13625|ASPP2_HUMAN Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens GN=TP53BP2 PE=1 SV=2;>sp|Q13625-2|ASPP2_HUMAN Isoform Bbp of Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens GN=TP53BP2 0.921695 10.708 0.921695 10.708 0.112 31.409 1 S TLRKNQSSEDILR CHK1;CK2;PKD 0.020748 0.112 31.409 _KNQpSSEDILR_ KNQS(0.922)S(0.078)EDILR KNQS(10.71)S(-10.71)EDILR 4 2 635.29537 0.72912 0 0 0 0 0 0 0 0 1210 889 520 520 470 534 4420 2670 Mix4_TiO2_Reinj_1_3 1095 4420 2670 Mix4_TiO2_Reinj_1_3 1095 Q13627-2;Q13627;Q13627-5 Q13627-2 Q13627-2 >sp|Q13627-2|DYR1A_HUMAN Isoform 1 of Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A;>sp|Q13627|DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2;>sp|Q1362 0.99854 28.3487 0.99854 28.3487 0.00646286 61.925 0 0 0 0 1 S NSGRARSDPTHQH CAMK2 0.042 0.00646286 61.925 _ARpSDPTHQHR_ ARS(0.999)DPT(0.001)HQHR ARS(28.35)DPT(-28.35)HQHR 3 3 428.85796 -0.25026 453370 0 0 0 453370 0 0 0 1211 889 739 739 4541 5157;5158 43000 26386 Mix4_InSol_TiO2_1 5409 43000 26386 Mix4_InSol_TiO2_1 5409 Q13627-2;Q13627 Q13627-2 Q13627-2 >sp|Q13627-2|DYR1A_HUMAN Isoform 1 of Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A;>sp|Q13627|DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2 0.984089 17.9133 0.984089 17.9133 0.000362072 88.001 0.963898 14.6164 0.926594 30.13 1 S GADREESPMTGVC CAMK2;Proline-directed 0.042 0.000362072 88.001 _QGADREEpSPMTGVCVQQSPVASS_ QGADREES(0.984)PMT(0.016)GVCVQQSPVASS QGADREES(17.91)PMT(-17.91)GVCVQQS(-88)PVAS(-88)S(-88) 8 3 834.02085 -0.015761 191090 0 0 0 0 0 113740 77350 1212 893 166 166 6560 7504 66392 40752 Mix4_TiO2_Reinj_1_4 5840 66392 40752 Mix4_TiO2_Reinj_1_4 5840 Q13765 Q13765 Q13765 >sp|Q13765|NACA_HUMAN Nascent polypeptide-associated complex subunit alpha OS=Homo sapiens GN=NACA PE=1 SV=1 0.985954 18.8236 0.985954 18.8236 9.77572E-13 134.19 1 S PTVQEESEEEEVD CK2 0.117 9.77572E-13 134.19 _VQGEAVSNIQENTQTPTVQEEpSEEEEVDETGVEVK_ VQGEAVSNIQENTQTPT(0.013)VQEES(0.986)EEEEVDET(0.001)GVEVK VQGEAVS(-93.19)NIQENT(-76.05)QT(-50.1)PT(-18.82)VQEES(18.82)EEEEVDET(-29.49)GVEVK 22 3 1314.2496 -0.0047602 1971400 0 0 0 1971400 0 0 0 1213 895 862 862 3602 4060 33862 20852 Mix4_TiO2_Reinj_1_5 5811 33862 20852 Mix4_TiO2_Reinj_1_5 5811 Q13873 Q13873 Q13873 >sp|Q13873|BMPR2_HUMAN Bone morphogenetic protein receptor type-2 OS=Homo sapiens GN=BMPR2 PE=1 SV=2 0.5 0 0.214771 -5.63022 0.0117299 71.813 0.5 0 0.00998077 73.346 1 S TRLNINSSPDEHE CK2 0.117 0.00998077 73.346 _LNINpSSPDEHEPLLR_ LNINS(0.5)S(0.5)PDEHEPLLR LNINS(0)S(0)PDEHEPLLR 5 3 605.28752 -0.10186 457260 0 0 0 457260 0 0 0 1214 895 863 863 3602 4060 33860 20849 Mix4_TiO2_1_5 5033 33862 20852 Mix4_TiO2_Reinj_1_5 5811 Q13873 Q13873 Q13873 >sp|Q13873|BMPR2_HUMAN Bone morphogenetic protein receptor type-2 OS=Homo sapiens GN=BMPR2 PE=1 SV=2 0.872181 8.34013 0.872181 8.34013 0.0117299 71.813 0.5 0 0.00998077 73.346 1 S RLNINSSPDEHEP CK2;Polo box;Proline-directed 0.00405 0.00998077 73.346 _LNINSpSPDEHEPLLR_ LNINS(0.128)S(0.872)PDEHEPLLR LNINS(-8.34)S(8.34)PDEHEPLLR 6 3 605.28752 0.039427 631630 174370 0 0 457260 0 0 0 1215 898;1637 113;74 113 3577;4936 4032;5612 47459 28982 Mix4_TiO2_Reinj_1_4 5657 47459 28982 Mix4_TiO2_Reinj_1_4 5657 Q13946;Q13946-2;Q13946-3;Q9NP56 Q13946;Q9NP56 Q13946 >sp|Q13946|PDE7A_HUMAN High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A OS=Homo sapiens GN=PDE7A PE=1 SV=2;>sp|Q13946-2|PDE7A_HUMAN Isoform PDE7A2 of High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A OS=Homo sapiens GN=PDE7A;>sp|Q1 1 56.8386 1 36.5607 0.385084 40.566 1 18.1764 0.787168 18.176 1 56.8386 0.0885362 56.839 1 51.5164 0.301636 51.516 1 22.5521 0.653504 22.552 1 S KVKRLLSFQRYFH;NIRRLLSFQRYLR CAMK2;CHK1;PKA;PKD 0.003024 0.0885362 56.839 _RLLpSFQR_ RLLS(1)FQR RLLS(56.84)FQR 4 2 500.26041 -0.25329 4725000 827370 61997 0 3587100 0 164690 83840 1216 898 84 84 4891 5562 46970 28740 Mix4_TiO2_Reinj_1_4 5241 46970 28740 Mix4_TiO2_Reinj_1_4 5241 Q13946;Q13946-2;Q13946-3 Q13946 Q13946 >sp|Q13946|PDE7A_HUMAN High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A OS=Homo sapiens GN=PDE7A PE=1 SV=2;>sp|Q13946-2|PDE7A_HUMAN Isoform PDE7A2 of High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A OS=Homo sapiens GN=PDE7A;>sp|Q1 0.999589 33.8557 0 0 0 0 0.999589 33.8557 0.0254344 54.135 0 0 0 0 1 S ESERRGSHPYIDF CAMK2;PKA 0.004788 0.0254344 54.135 _RGpSHPYIDFR_ RGS(1)HPYIDFR RGS(33.86)HPY(-33.86)IDFR 3 2 664.30079 0.49937 4507600 0 0 0 4507600 0 0 0 1217 900 493 493 514 580 4749 2867 Mix4_InSol_Tio2_Reinj_1 2676 4752 2870 Mix4_TiO2_Reinj_1_5 2425 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.395792 0 0.368921 0 0.0153799 66.376 0 0 0.28733 -1.3996 1.84765E-34 178.37 0 0 0.395792 0 3.32285E-07 107.57 1 S AKASNTSTPTKGN CK1 0.081 1.84765E-34 178.37 _ASNTpSTPTKGNTETSASASQTNHVK_ AS(0.069)NT(0.069)S(0.396)T(0.396)PT(0.047)KGNT(0.024)ETSASASQTNHVK AS(-7.59)NT(-7.59)S(0)T(0)PT(-9.29)KGNT(-12.21)ET(-31.99)S(-51.65)AS(-69.29)AS(-91.31)QT(-104.99)NHVK 5 3 867.05924 -0.11258 0 0 0 0 0 0 0 0 1218 900 662 662 673 774 6473 3845 Mix4_TiO2_Reinj_1_5 8501 6472 3844 Mix4_TiO2_Reinj_1_1 8156 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.554273 0.94655 0.548449 0.844302 0.000168199 91.733 0 0 0.554273 0.94655 1.53123E-07 113.25 1 S PGGDDLSKSPEEK 1.53123E-07 113.25 _CLLADLPLPPELPGGDDLpSKSPEEK_ CLLADLPLPPELPGGDDLS(0.554)KS(0.446)PEEK CLLADLPLPPELPGGDDLS(0.95)KS(-0.95)PEEK 19 3 924.1134 -0.12174 432250 48519 0 0 383730 0 0 0 1219 900 664 664 673 774 6471 3843 Mix4_TiO2_1_5 7751 6472 3844 Mix4_TiO2_Reinj_1_1 8156 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.875598 8.47479 0.875598 8.47479 0.000168199 91.733 0 0 0.5 0 1.53123E-07 113.25 1 S GDDLSKSPEEKKT CK2;NEK6;Proline-directed 0.05 1.53123E-07 113.25 _CLLADLPLPPELPGGDDLSKpSPEEK_ CLLADLPLPPELPGGDDLS(0.124)KS(0.876)PEEK CLLADLPLPPELPGGDDLS(-8.47)KS(8.47)PEEK 21 3 924.1134 -0.503 255130 82875 0 0 172250 0 0 0 1220 900 383 383 2203 2495 20220 12432 Mix4_TiO2_Reinj_1_5 5320 20219 12431 Mix4_TiO2_Reinj_1_1 4788 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.99686 25.029 0.973282 15.6143 0.000730804 94.485 0 0 0.99686 25.029 0.00065556 94.995 0.979721 16.8437 0.0163264 67.784 0.409404 -1.59137 0.00212926 85.004 1 S ERGGDVSPSPYSS Proline-directed 0.05 0.00065556 94.995 _GGDVpSPSPYSSSSWR_ GGDVS(0.997)PS(0.003)PYSSSSWR GGDVS(25.03)PS(-25.03)PY(-67.61)S(-53.13)S(-55.38)S(-63.32)S(-70.96)WR 5 2 824.83559 0.49444 1012800 180830 0 0 734950 0 96997 0 1221 900 385 385 2203 2495 20216 12428 Mix4_InSol_Tio2_Reinj_1 5557 20219 12431 Mix4_TiO2_Reinj_1_1 4788 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.590595 1.59137 0.146697 -7.64679 0.000730804 94.485 0 0 0.0152743 -18.0931 0.00065556 94.995 0.0202643 -16.8437 0.0163264 67.784 0.590595 1.59137 0.00212926 85.004 1 S GGDVSPSPYSSSS GSK3;Proline-directed 0.05 0.00065556 94.995 _GGDVSPpSPYSSSSWR_ GGDVS(0.409)PS(0.591)PYSSSSWR GGDVS(-1.59)PS(1.59)PY(-73.59)S(-57.56)S(-64.53)S(-74.57)S(-81.55)WR 7 2 824.83559 0.21556 108600 0 0 0 0 0 0 108600 1222 900 525 525 2740;2814 3123;3206 26913 16821 Mix4_TiO2_Reinj_1_5 4221 26912 16820 Mix4_TiO2_Reinj_1_1 3665 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.999412 33.8413 0.389853 -1.25198 0.136124 39.391 0 0 0.999412 33.8413 0.0122417 71.306 0 0 1 S KIEHAPSPSSGGT Proline-directed 0.05 0.0122417 71.306 _IKIEHAPpSPSSGGTLK_ IKIEHAPS(0.999)PSSGGTLK IKIEHAPS(33.84)PS(-33.84)S(-40.58)GGT(-40.58)LK 8 3 567.95723 -1.6435 202190 0 0 0 202190 0 0 0 1223 900 527 527 2740;2814 3123;3206 25931 16055 Mix4_TiO2_1_5 2895 26912 16820 Mix4_TiO2_Reinj_1_1 3665 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.520114 1.25198 0.520114 1.25198 0.136124 39.391 0 0 0.287741 0 0.0122417 71.306 0 0 1 S EHAPSPSSGGTLK 0.0122417 71.306 _IEHAPSPpSSGGTLK_ IEHAPS(0.39)PS(0.52)S(0.089)GGT(0.001)LK IEHAPS(-1.25)PS(1.25)S(-7.67)GGT(-26.64)LK 8 2 730.84269 -0.44445 41239 41239 0 0 0 0 0 0 1224 900 528 528 2740;2814 3123;3206 25932 16056 Mix4_TiO2_Reinj_1_1 2985 26912 16820 Mix4_TiO2_Reinj_1_1 3665 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.287741 0 0.17508 -2.68379 0.136124 39.391 0 0 0.287741 0 0.0122417 71.306 0 0 1 S HAPSPSSGGTLKN CK1 0.081 0.0122417 71.306 _IEHAPSPpSSGGTLK_ IEHAPS(0.137)PS(0.288)S(0.288)GGT(0.288)LK IEHAPS(-3.23)PS(0)S(0)GGT(0)LK 9 2 730.84269 0.55936 0 0 0 0 0 0 0 0 1225 900 864 864 3809 4304 36194 22373 Mix4_TiO2_1_5 2883 36197 22376 Mix4_TiO2_Reinj_1_1 3006 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.420811 0 0.420811 0 0.411077 21.334 0.0515321 -11.5853 0.696314 11.585 0.0894542 -6.36889 0.00325837 86.413 0 0 0.00853343 -20.4994 0.435486 20.499 0 0 1 S LARLYSSEESRPY NEK6 0.076 0.00325837 86.413 _LYSpSEESRPYTNK_ LY(0.003)S(0.003)S(0.421)EES(0.421)RPY(0.076)T(0.076)NK LY(-21.33)S(-21.33)S(0)EES(0)RPY(-7.43)T(-7.43)NK 4 3 551.91005 0.1329 0 0 0 0 0 0 0 0 1226 900 867 867 3809 4304 36194 22373 Mix4_TiO2_1_5 2883 36197 22376 Mix4_TiO2_Reinj_1_1 3006 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.420811 0 0.420811 0 0.411077 21.334 0.0515321 -11.5853 0.696314 11.585 0.0894542 -6.36889 0.00325837 86.413 0 0 0.00853343 -20.4994 0.435486 20.499 0 0 1 S LYSSEESRPYTNK CK1 0.081 0.00325837 86.413 _LYSpSEESRPYTNK_ LY(0.003)S(0.003)S(0.421)EES(0.421)RPY(0.076)T(0.076)NK LY(-21.33)S(-21.33)S(0)EES(0)RPY(-7.43)T(-7.43)NK 7 3 551.91005 0.1329 0 0 0 0 0 0 0 0 1227 900 1146 1146 4750 5396 45321 27722 Mix4_TiO2_1_5 4383 45321 27722 Mix4_TiO2_1_5 4383 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.495306 0 0.495306 0 0.0184244 68.934 0 0 0.445615 0 0.026444 64.243 0.219559 -3.96512 0.487668 47.778 0 0 1 S EKQTDPSTPQQES 0.0184244 68.934 _QTDPpSTPQQESSKPLGGIQPSSQTIQPK_ QT(0.006)DPS(0.495)T(0.495)PQQES(0.001)S(0.001)KPLGGIQPSSQTIQPK QT(-18.89)DPS(0)T(0)PQQES(-25.2)S(-25.2)KPLGGIQPS(-67.78)S(-68.93)QT(-68.93)IQPK 5 3 1015.4906 0.18648 0 0 0 0 0 0 0 0 1228 901 80 80 2713;3987 3090;3092;4541;4543 37753 23178 Mix4_TiO2_Reinj_1_4 1266 37753 23178 Mix4_TiO2_Reinj_1_4 1266 Q14103;Q14103-3 Q14103 Q14103 >sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens GN=HNRNPD PE=1 SV=1;>sp|Q14103-3|HNRPD_HUMAN Isoform Dx7 of Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens GN=HNRNPD 0.998118 27.0008 0.572095 2.01404 1.00806E-25 180.96 0 0 0.998118 27.0008 0.00430061 81.534 0 0 0.625536 5.2967 1.94848E-15 145.58 0.441823 0 1.71044E-21 172.26 2 S EEDEGHSNSSPRH 0.00430061 81.534 _NEEDEGHpSNSpSPR_ NEEDEGHS(0.998)NS(0.057)S(0.945)PR NEEDEGHS(27)NS(-12.35)S(12.35)PR 8 2 809.26435 0.33496 354870 0.099221 0 0 0 354870 0 0 0 1229 901 82 82 2713;3987 3090;3092;4541;4543 25621 15845 Mix4_TiO2_Reinj_1_6 1774 25614 15830 Mix4_TiO2_1_4 1638 Q14103;Q14103-3 Q14103 Q14103 >sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens GN=HNRNPD PE=1 SV=1;>sp|Q14103-3|HNRPD_HUMAN Isoform Dx7 of Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens GN=HNRNPD 0.809349 6.9706 0.482782 0 1.00806E-25 180.96 0 0 0.809349 6.9706 7.86083E-09 159.3 0 0 0.448084 0 1.94848E-15 145.58 0.792919 6.55943 1.71044E-21 172.26 1 S DEGHSNSSPRHSE 1.00806E-25 180.96 _IDASKNEEDEGHSNpSSPR_ IDASKNEEDEGHS(0.163)NS(0.809)S(0.028)PR IDAS(-37.14)KNEEDEGHS(-6.97)NS(6.97)S(-14.62)PR 15 3 684.61492 0.043504 11022000 3.0818 0 0 0 9615600 0 0 1406900 1230 901 83 83 2713;3987 3090;3092;4541;4543 37728 23165 Mix4_TiO2_Reinj_1_4 1252 25614 15830 Mix4_TiO2_1_4 1638 Q14103;Q14103-3 Q14103 Q14103 >sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens GN=HNRNPD PE=1 SV=1;>sp|Q14103-3|HNRPD_HUMAN Isoform Dx7 of Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens GN=HNRNPD 0.99791 26.8378 0.997152 25.5381 1.00806E-25 180.96 0 0 0.99791 26.8378 7.86083E-09 159.3 0 0 0.847073 7.43718 1.94848E-15 145.58 0.683748 6.00761 1.71044E-21 172.26 1 S EGHSNSSPRHSEA CDK1;CK1;GSK3;Polo box;Proline-directed 0.00405 1.00806E-25 180.96 _NEEDEGHSNSpSPR_ NEEDEGHSNS(0.002)S(0.998)PR NEEDEGHS(-46.33)NS(-26.84)S(26.84)PR 11 2 769.28118 -0.43355 8739700 2.4436 316060 0 0 6914100 0 985150 524460 1231 906 881 881 3435;4935 3879;5611 47452 28978 Mix4_TiO2_1_5 2490 32231 19911 Mix4_TiO2_Reinj_1_5 3159 Q14152 Q14152 Q14152 >sp|Q14152|EIF3A_HUMAN Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens GN=EIF3A PE=1 SV=1 0.903114 10.1747 0.903114 10.1747 0.104847 47.468 0.409388 -1.31561 0.0194933 63.086 0.854848 9.15679 0.593534 13.154 0 0 1 S ERRLGDSSLSRKD NEK6 0.076 0.0194933 63.086 _RLGDpSSLSR_ RLGDS(0.903)S(0.087)LS(0.01)R RLGDS(10.17)S(-10.17)LS(-19.5)R 5 2 535.75315 -0.18205 197690 39396 0 0 0 0 158290 0 1232 906 882 882 3435;4935 3879;5611 32231 19911 Mix4_TiO2_Reinj_1_5 3159 32231 19911 Mix4_TiO2_Reinj_1_5 3159 Q14152 Q14152 Q14152 >sp|Q14152|EIF3A_HUMAN Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens GN=EIF3A PE=1 SV=1 0.992627 21.5228 0.990771 20.6291 0.104847 47.468 0.992627 21.5228 0.0194933 63.086 0.103803 -9.15679 0.593534 13.154 0 0 1 S RRLGDSSLSRKDS PLK1 0.033462 0.0194933 63.086 _LGDSpSLSR_ LGDS(0.007)S(0.993)LSR LGDS(-21.52)S(21.52)LS(-34.14)R 5 2 457.70259 -0.17166 137360 15216 0 0 122140 0 0 0 1233 906 884 884 3435;4935 3879;5611 47453 28979 Mix4_TiO2_Reinj_1_5 3119 32231 19911 Mix4_TiO2_Reinj_1_5 3159 Q14152 Q14152 Q14152 >sp|Q14152|EIF3A_HUMAN Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens GN=EIF3A PE=1 SV=1 0.554238 1.31561 0.0101359 -19.4988 0.104847 47.468 0.554238 1.31561 0.0194933 63.086 0.0413493 -13.1542 0.593534 13.154 0 0 1 S LGDSSLSRKDSRW CK1;CK2;GSK3 0.081 0.0194933 63.086 _RLGDSSLpSR_ RLGDS(0.409)S(0.036)LS(0.554)R RLGDS(-1.32)S(-11.83)LS(1.32)R 8 2 535.75315 0.15778 0 0 0 0 0 0 0 0 1234 907 694 694 3753 4233 35469 21908 Mix4_TiO2_Reinj_1_3 6939 35469 21908 Mix4_TiO2_Reinj_1_3 6939 Q14156;Q14156-2;Q14156-3 Q14156 Q14156 >sp|Q14156|EFR3A_HUMAN Protein EFR3 homolog A OS=Homo sapiens GN=EFR3A PE=1 SV=2;>sp|Q14156-2|EFR3A_HUMAN Isoform 2 of Protein EFR3 homolog A OS=Homo sapiens GN=EFR3A;>sp|Q14156-3|EFR3A_HUMAN Isoform 3 of Protein EFR3 homolog A OS=Homo sapiens GN=EFR3A 1 71.0746 0.152822 -6.61415 1.16553 9.8119 0 0 1 71.0746 0.000132766 97.651 0 0 0 0 1 S TDEDRLSRRKSIV GSK3;PKA 0.042 0.000132766 97.651 _LSVPYVPQVTDEDRLpSR_ LSVPYVPQVTDEDRLS(1)R LS(-97.65)VPY(-97.65)VPQVT(-71.07)DEDRLS(71.07)R 16 2 1027.5013 0.28997 690970 0 0 0 690970 0 0 0 1235 908 496 496 3079 3500 29327 18296 Mix4_TiO2_Reinj_1_5 1260 29327 18296 Mix4_TiO2_Reinj_1_5 1260 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.786058 7.03241 0.786058 7.03241 0.0211096 61.118 1 S KKASLTSKIPALA CK1 0.081 0.0211096 61.118 _KKASLTpSK_ KKAS(0.156)LT(0.058)S(0.786)K KKAS(-7.03)LT(-11.3)S(7.03)K 7 2 471.75463 -0.12122 115050 0 0 0 115050 0 0 0 1236 908 412 412 4243;4244 4831;4832 40430 24908 Mix4_InSol_Tio2_Reinj_1 4051 40428 24907 Mix4_TiO2_Reinj_1_5 3930 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.429273 3.53426 4.03874E-07 -63.9247 1.68666E-05 132.58 0.347638 0 2.54279E-13 179.73 0 0 0.429273 3.53426 1.09964 3.5343 1 S LKNPSDSAVHSPF GSK3 0.081 2.54279E-13 179.73 _NPSDpSAVHSPFTKR_ NPS(0.19)DS(0.429)AVHS(0.19)PFT(0.19)KR NPS(-3.53)DS(3.53)AVHS(-3.53)PFT(-3.53)KR 5 3 541.58227 -0.17538 0 0 0 0 0 0 0 0 1237 908 416 416 4243;4244 4831;4832 40428 24907 Mix4_TiO2_Reinj_1_5 3930 40428 24907 Mix4_TiO2_Reinj_1_5 3930 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.999747 35.9786 0.997047 25.2858 1.68666E-05 132.58 0.999747 35.9786 2.54279E-13 179.73 0 0 0.190242 -3.53426 1.09964 3.5343 1 S SDSAVHSPFTKRQ CK1;ERK/MAPK;Proline-directed 0.0034 2.54279E-13 179.73 _NPSDSAVHpSPFTK_ NPSDSAVHS(1)PFTK NPS(-134.09)DS(-62.2)AVHS(35.98)PFT(-35.98)K 9 2 733.81921 -0.26391 448850 78128 0 0 370720 0 0 0 1238 908 604 604 5077;5078;6770;6771 5772;5773;5774;5775;7747;7748 49074 29980 Mix4_TiO2_Reinj_1_1 2879 49092 29994 Mix4_TiO2_1_5 4054 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.448907 0 0.352247 -1.47252 0.0660685 46.398 0 0 0.448907 0 0.0029791 78.316 0 0 0.100696 -3.73572 0.01552 67.254 0.0238271 -14.3091 0.0748378 53.211 1 S QTRRYPSSISSSP CAMK2;GSK3 0.042 0.00105067 86.098 _RYPpSSISSSPQK_ RY(0.022)PS(0.449)S(0.449)IS(0.022)S(0.022)S(0.037)PQK RY(-13.14)PS(0)S(0)IS(-13.14)S(-13.14)S(-10.86)PQK 4 2 708.82958 -0.2269 0 0 0 0 0 0 0 0 1239 908 605 605 5077;5078;6770;6771 5772;5773;5774;5775;7747;7748 49116 30001 Mix4_TiO2_1_5 4241 49084 29984 Mix4_TiO2_1_5 2706 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.577858 2.24609 0.577858 2.24609 0.0660685 46.398 0 0 0.448907 0 0.0029791 78.316 0 0 0.149933 -2.00686 0.01552 67.254 0.0238271 -14.3091 0.0748378 53.211 2 S TRRYPSSISSSPQ GSK3 0.081 0.0660685 46.398 _RYPSpSIpSSSPQKDLTQAK_ RY(0.011)PS(0.333)S(0.578)IS(0.361)S(0.353)S(0.353)PQKDLT(0.011)QAK RY(-20.19)PS(-2.25)S(2.25)IS(0)S(0)S(0)PQKDLT(-20.19)QAK 5 3 718.32737 0.096025 153210 153210 0 0 0 0 0 0 1240 908 607 607 5077;5078;6770;6771 5772;5773;5774;5775;7747;7748 68665 42134 Mix4_TiO2_Reinj_1_5 4899 49092 29994 Mix4_TiO2_1_5 4054 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.883946 9.95597 0.771511 8.31481 0.00105067 86.098 0 0 0.883946 9.95597 0.0029791 78.316 0 0 0.329343 0 0.01552 67.254 0.440318 0 0.0748378 53.211 1 S RYPSSISSSPQKD CK1 0.081 0.00105067 86.098 _YPSSIpSSSPQKDLTQAK_ YPSS(0.014)IS(0.884)S(0.089)S(0.013)PQKDLTQAK Y(-64.69)PS(-32.88)S(-18.14)IS(9.96)S(-9.96)S(-18.41)PQKDLT(-67.25)QAK 6 3 639.63822 -0.22861 725090 57840 0 0 667260 0 0 0 1241 908 608 608 5077;5078;6770;6771 5772;5773;5774;5775;7747;7748 49087 29988 Mix4_InSol_TiO2_1 5049 49092 29994 Mix4_TiO2_1_5 4054 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.828186 7.52217 0.447042 2.52941 0.00105067 86.098 0 0 0.597603 2.14557 0.0029791 78.316 0 0 0.828186 7.52217 0.01552 67.254 0.440318 0 0.0748378 53.211 1 S YPSSISSSPQKDL CK1 0.081 0.00105067 86.098 _RYPSSISpSSPQKDLTQAK_ RYPS(0.001)S(0.001)IS(0.147)S(0.828)S(0.022)PQKDLTQAK RY(-52.93)PS(-27.6)S(-27.6)IS(-7.52)S(7.52)S(-15.73)PQKDLT(-35.26)QAK 8 2 1037.0043 0.095133 4838100 0 0 0 4495400 0 342640 0 1242 908 609 609 5077;5078;6770;6771 5772;5773;5774;5775;7747;7748 49072 29977 Mix4_TiO2_1_5 2713 49092 29994 Mix4_TiO2_1_5 4054 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.993828 25.1103 0.993828 25.1103 0.00105067 86.098 0 0 0.759863 6.8849 0.0029791 78.316 0 0 0.661232 2.98221 0.01552 67.254 0.773825 5.65489 0.0748378 53.211 1 S PSSISSSPQKDLT CDK1;CDK2;CK1;Polo box;Proline-directed 0.00405 0.00105067 86.098 _RYPSSISSpSPQK_ RY(0.001)PS(0.001)S(0.001)IS(0.001)S(0.003)S(0.994)PQK RY(-32.29)PS(-29.4)S(-30.96)IS(-32.29)S(-25.11)S(25.11)PQK 9 2 708.82958 -0.24039 5709100 1617200 0 0 387680 0 1520900 2183400 1243 908 453 453 5546 6320 54283 33239 Mix4_InSol_Tio2_Reinj_3 2442 54297 33256 Mix4_TiO2_Reinj_1_5 4439 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.842202 8.73922 0.576831 1.34574 3.64447E-11 128.43 0.304384 0 7.29996E-07 103.66 0.149413 -7.54954 1.2087E-16 146.21 0 0 0.496172 0 1.37372E-16 144.78 0.842202 8.73922 3.62932E-07 110.92 1 S AAPPPPSSPLPSK 1.2087E-16 146.21 _SPAVATSTAAPPPPpSSPLPSK_ SPAVATSTAAPPPPS(0.842)S(0.113)PLPS(0.044)K S(-33.5)PAVAT(-33.5)S(-33.5)T(-33.5)AAPPPPS(8.74)S(-8.74)PLPS(-12.85)K 15 2 1020.5061 0.65182 454850 167860 0 0 0 0 0 286990 1244 908 454 454 5546 6320 54279 33234 Mix4_InSol_Tio2_Reinj_1 4662 54297 33256 Mix4_TiO2_Reinj_1_5 4439 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.970391 15.7363 0.852568 7.73116 3.64447E-11 128.43 0.875548 8.48445 7.29996E-07 103.66 0.86454 8.05214 1.2087E-16 146.21 0 0 0.866806 8.26625 1.37372E-16 144.78 0.970391 15.7363 3.62932E-07 110.92 1 S APPPPSSPLPSKS ERK/MAPK;GSK3;Polo box;Proline-directed;WW GroupIV 0.0023175 1.2087E-16 146.21 _SPAVATSTAAPPPPSpSPLPSK_ SPAVATSTAAPPPPS(0.026)S(0.97)PLPS(0.004)K S(-110.92)PAVAT(-103.02)S(-83.86)T(-77.23)AAPPPPS(-15.74)S(15.74)PLPS(-24.18)K 16 2 1020.5061 -0.20353 14830000 2012600 431140 0 8880600 0 2139300 1366300 1245 908 458 458 5546 6320 54282 33238 Mix4_InSol_Tio2_Reinj_2 3372 54297 33256 Mix4_TiO2_Reinj_1_5 4439 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.482279 0.684041 0.333296 0 3.64447E-11 128.43 0.304384 0 7.29996E-07 103.66 0.117673 -8.26359 1.2087E-16 146.21 0 0 0.375664 0.804616 1.37372E-16 144.78 0.482279 0.684041 3.62932E-07 110.92 1 S PSSPLPSKSTSAP CK1;GSK3 0.081 1.2087E-16 146.21 _SPAVATSTAAPPPPSSPLPpSK_ S(0.007)PAVAT(0.007)S(0.007)T(0.007)AAPPPPS(0.079)S(0.412)PLPS(0.482)K S(-18.66)PAVAT(-18.66)S(-18.66)T(-18.66)AAPPPPS(-7.83)S(-0.68)PLPS(0.68)K 20 3 680.67316 0.28228 0 0 0 0 0 0 0 0 1246 908 467 467 5800 6607;6609;6611 57150 34850 Mix4_TiO2_Reinj_1_5 3234 57149 34849 Mix4_TiO2_Reinj_1_1 2749 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.464847 0 0 0 0.464847 0 1.5413E-11 121.81 0.249266 -1.77606 5.79514E-08 116.27 0.331886 0 0.0399317 59.418 1 S TSAPQMSPGSSDN GSK3;Proline-directed 0.05 1.5413E-11 121.81 _STSAPQMpSPGSSDNQSSSPQPAQQK_ STSAPQMS(0.465)PGS(0.465)S(0.07)DNQSSSPQPAQQK S(-42.03)T(-42.03)S(-42.03)APQMS(0)PGS(0)S(-8.21)DNQS(-47.96)S(-47.41)S(-63.79)PQPAQQK 8 3 871.36919 -1.4058 0 0 0 0 0 0 0 0 0 1247 908 470 470 5800 6607;6609;6611 57149 34849 Mix4_TiO2_Reinj_1_1 2749 57149 34849 Mix4_TiO2_Reinj_1_1 2749 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.469328 0 0 0 0.469328 0 1.5413E-11 121.81 0.375206 0 5.79514E-08 116.27 0.381933 1.81177 5.79608E-07 99.723 1 S PQMSPGSSDNQSS CK1 0.081 1.5413E-11 121.81 _STSAPQMSPGpSSDNQSSSPQPAQQK_ STSAPQMS(0.061)PGS(0.469)S(0.469)DNQSSSPQPAQQK S(-65.44)T(-64.71)S(-64.71)APQMS(-8.84)PGS(0)S(0)DNQS(-53.88)S(-58.98)S(-66.81)PQPAQQK 11 3 871.36919 -0.49516 0 0 0 0 0 0 0 0 0 1248 908 471 471 5800 6607;6609;6611 57146 34845 Mix4_InSol_TiO2_1 3419 57149 34849 Mix4_TiO2_Reinj_1_1 2749 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.486726 1.94178 0 0 0.469328 0 1.5413E-11 121.81 0.486726 1.94178 5.79514E-08 116.27 0.417468 1.8017 5.79608E-07 99.723 1 S QMSPGSSDNQSSS CK1;GSK3 0.081 1.5413E-11 121.81 _STSAPQMSPGSpSDNQSSSPQPAQQK_ STSAPQMS(0.201)PGS(0.311)S(0.487)DNQS(0.001)SSPQPAQQK S(-44.61)T(-43.96)S(-52.03)APQMS(-3.84)PGS(-1.94)S(1.94)DNQS(-27.66)S(-43.26)S(-60.99)PQPAQQK 12 3 871.36919 -0.80273 0 0 0 0 0 0 0 0 0 1249 908 477 477 5800 6607;6609;6611 57170 34855 Mix4_InSol_Tio2_Reinj_1 3134 57170 34855 Mix4_InSol_Tio2_Reinj_1 3134 Q14157;Q14157-3;Q14157-1;Q14157-4 Q14157 Q14157 >sp|Q14157|UBP2L_HUMAN Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L PE=1 SV=2;>sp|Q14157-3|UBP2L_HUMAN Isoform 3 of Ubiquitin-associated protein 2-like OS=Homo sapiens GN=UBAP2L;>sp|Q14157-1|UBP2L_HUMAN Isoform 2 of Ubiquitin-associated pr 0.795216 6.45583 0 0 1.94343E-07 -63.7874 1.5413E-11 121.81 3.87206E-07 -60.9934 5.79514E-08 116.27 0.795216 6.45583 0.0399317 59.418 2 S SDNQSSSPQPAQQ Polo box;Proline-directed 0.00405 0.0399317 59.418 _STSAPQMpSPGSSDNQSSpSPQPAQQK_ STSAPQMS(0.332)PGS(0.332)S(0.332)DNQS(0.029)S(0.18)S(0.795)PQPAQQK S(-45.18)T(-44.74)S(-44.3)APQMS(0)PGS(0)S(0)DNQS(-15.06)S(-6.46)S(6.46)PQPAQQK 18 3 898.02464 0.14002 109310 0.052284 0 0 0 0 0 0 109310 1250 909 664 664 298;2112;2113 338;339;2394;2395;2396;2397 19435 11830 Mix4_TiO2_Reinj_1_3 5254 19434 11826 Mix4_TiO2_1_3 4458 Q14164 Q14164 Q14164 >sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon OS=Homo sapiens GN=IKBKE PE=1 SV=1 1 95.8582 1 102.391 1.01376E-10 137.1 0 0 1 95.8582 2.79955E-09 129.76 0.99988 43.9729 0.163087 43.973 0.999998 61.8033 0.00552296 76.071 1 S AKGAQASPPPIAP Proline-directed 0.05 1.01376E-10 137.1 _GAQApSPPPIAPYPSPTR_ GAQAS(1)PPPIAPYPSPTR GAQAS(95.86)PPPIAPY(-95.86)PS(-107.33)PT(-129.76)R 5 2 893.92983 0.58914 8979800 1731700 0 0 5560900 0 1099800 587470 1251 909 673 673 298;2112;2113 338;339;2394;2395;2396;2397 19469 11848 Mix4_InSol_Tio2_Reinj_1 5056 19434 11826 Mix4_TiO2_1_3 4458 Q14164 Q14164 Q14164 >sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon OS=Homo sapiens GN=IKBKE PE=1 SV=1 0.941033 13.6181 0.99789 26.7524 3.25652E-09 128.49 0 0 0.865264 8.7606 2.79955E-09 129.76 0.985176 18.2257 0.00120077 84.243 0.941033 13.6181 0.00552296 76.071 1 S PIAPYPSPTRKDL CDK1;CDK2;Proline-directed 0.0057 1.01376E-10 137.1 _GAQASPPPIAPYPpSPTRK_ GAQASPPPIAPY(0.018)PS(0.941)PT(0.041)RK GAQAS(-72.04)PPPIAPY(-17.17)PS(13.62)PT(-13.62)RK 14 2 957.97731 1.0275 1588300 0 0 0 1476600 0 0 111610 1252 911 1681 1681 5610 6393 54836 33579 Mix4_TiO2_Reinj_1_5 3464 54836 33579 Mix4_TiO2_Reinj_1_5 3464 Q14185 Q14185 Q14185 >sp|Q14185|DOCK1_HUMAN Dedicator of cytokinesis protein 1 OS=Homo sapiens GN=DOCK1 PE=1 SV=2 1 66.0925 1 36.8482 0.135967 36.848 0 0 1 66.0925 0.0139527 66.093 1 S KKMHSRSQDKLDK 0.0139527 66.093 _pSQDKLDKDDLEK_ S(1)QDKLDKDDLEK S(66.09)QDKLDKDDLEK 1 2 757.34272 0.80124 336200 63350 0 0 272850 0 0 0 1253 914 4368 4368 5949;6203 6784;6785;7085;7086 58672 35568 Mix4_InSol_TiO2_1 5704 58681 35587 Mix4_TiO2_Reinj_1_1 4833 Q14204 Q14204 Q14204 >sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 0.968956 15.8177 0.955557 18.0957 0.00278452 88.632 0.674148 7.083 0.627685 13.931 0.929073 12.0304 0.000126785 115.49 0.536417 4.11962 0.604188 14.734 0.968956 15.8177 0.00238905 90.483 0.944469 16.3572 0.00454807 80.375 1 S KKTRTDSTSDGRP CAMK2;CK1;CK2;PKA/AKT 0.00111111 0.000126785 115.49 _TDpSTSDGRPAWMR_ T(0.002)DS(0.969)T(0.025)S(0.003)DGRPAWMR T(-25.98)DS(15.82)T(-15.82)S(-24.79)DGRPAWMR 3 3 520.54846 -0.51026 13980000 2261800 30666 0 9493500 14268 1552500 627210 1254 914 4370 4370 5949;6203 6784;6785;7085;7086 61475 37264 Mix4_TiO2_Reinj_1_1 4474 58681 35587 Mix4_TiO2_Reinj_1_1 4833 Q14204 Q14204 Q14204 >sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 0.849042 8.2082 0.204578 -1.59584 0.00278452 88.632 0.131964 -7.083 0.627685 13.931 0.849042 8.2082 0.000126785 115.49 0.20775 -4.11962 0.604188 14.734 0.358991 0 0.00238905 90.483 0.167205 -2.96814 0.00454807 80.375 1 S TRTDSTSDGRPAW CK1 0.143 0.000126785 115.49 _TRTDSTpSDGRPAWMR_ T(0.001)RT(0.001)DS(0.021)T(0.128)S(0.849)DGRPAWMR T(-30.23)RT(-28.21)DS(-16.15)T(-8.21)S(8.21)DGRPAWMR 7 2 908.89345 -0.07877 163590 0 0 0 163590 0 0 0 1255 915 405 405 311;6190 354;7067;7068 61289 37121 Mix4_TiO2_Reinj_1_3 3349 61289 37121 Mix4_TiO2_Reinj_1_3 3349 Q14247 Q14247 Q14247 >sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sapiens GN=CTTN PE=1 SV=2 1 76.3113 0.989602 23.3853 0.627557 27.185 1 76.3113 3.63321E-12 138.1 2 S TQTPPVSPAPQPT CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.63321E-12 138.1 _TQpTPPVpSPAPQPTEER_ T(0.076)QT(0.924)PPVS(1)PAPQPTEER T(-10.83)QT(10.83)PPVS(76.31)PAPQPT(-76.31)EER 7 2 947.90282 -1.8916 836250 323090 0 0 513150 0 0 0 1256 915 418 418 3635 4097 34165 21071 Mix4_TiO2_Reinj_1_3 6309 34164 21070 Mix4_TiO2_1_3 5475 Q14247 Q14247 Q14247 >sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sapiens GN=CTTN PE=1 SV=2 0.968482 14.8761 0.868517 8.19908 0.000596469 96.556 0 0 0.968482 14.8761 0.00112994 93.334 1 S EERLPSSPVYEDA ERK/MAPK;NEK6;Polo box;Proline-directed;WW GroupIV 0.0023175 0.000596469 96.556 _LPSpSPVYEDAASFK_ LPS(0.032)S(0.968)PVYEDAASFK LPS(-14.88)S(14.88)PVY(-52.15)EDAAS(-93.33)FK 4 2 795.858 0.30365 1444100 432210 0 0 1011800 0 0 0 1257 917 136 136 961 1083 9211 5652 Mix4_TiO2_Reinj_1_5 5169 9211 5652 Mix4_TiO2_Reinj_1_5 5169 Q14498;Q14498-2 Q14498 Q14498 >sp|Q14498|RBM39_HUMAN RNA-binding protein 39 OS=Homo sapiens GN=RBM39 PE=1 SV=2;>sp|Q14498-2|RBM39_HUMAN Isoform HCC1.3 of RNA-binding protein 39 OS=Homo sapiens GN=RBM39 1 150.681 1 88.5927 1.16283E-12 143.48 0 0 1 150.681 4.77214E-16 157.87 0 0 0.994885 22.8892 0.715754 22.889 0 0 1 S PFRKDKSPVREPI CDK1;CDK2;Proline-directed 0.0057 4.77214E-16 157.87 _DKpSPVREPIDNLTPEER_ DKS(1)PVREPIDNLTPEER DKS(150.68)PVREPIDNLT(-150.68)PEER 3 3 692.33168 -0.081307 5385200 1060000 0 0 4248700 0 76531 0 1258 917 97 97 6787 7766 68880 42244 Mix4_TiO2_1_3 2628 68880 42244 Mix4_TiO2_1_3 2628 Q14498;Q14498-2 Q14498 Q14498 >sp|Q14498|RBM39_HUMAN RNA-binding protein 39 OS=Homo sapiens GN=RBM39 PE=1 SV=2;>sp|Q14498-2|RBM39_HUMAN Isoform HCC1.3 of RNA-binding protein 39 OS=Homo sapiens GN=RBM39 0.992409 21.3209 0.992409 21.3209 0.0429898 49.273 0.746452 9.46064 0.703691 9.4606 0.980743 19.9536 0.122629 37.146 0.835656 11.834 0.63291 11.834 0.480247 4.42789 0.853786 4.4279 1 S FRGRYRSPYSGPK CAMK2;PKA/AKT;Proline-directed 0.001764 0.0429898 49.273 _YRpSPYSGPK_ Y(0.007)RS(0.992)PYSGPK Y(-21.32)RS(21.32)PY(-35.86)S(-49.27)GPK 3 2 567.75261 0.48252 1391900 109070 13932 0 1065500 0 203430 0 1259 920 2670 2670 3441 3886 32428 20088 Mix4_TiO2_Reinj_1_1 6023 32427 20087 Mix4_TiO2_1_1 5299 Q14573 Q14573 Q14573 >sp|Q14573|ITPR3_HUMAN Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens GN=ITPR3 PE=1 SV=2 1 64.8544 1 114.864 0.000296973 114.86 1 64.8544 0.014638 64.854 0 0 0 0 1 S DVQNCISR_____ 0.000296973 114.86 _LGFVDVQNCIpSR_ LGFVDVQNCIS(1)R LGFVDVQNCIS(64.85)R 11 2 744.33926 0.92757 190500 32335 0 0 158160 0 0 0 1260 920 1832 1832 6344 7254 63992 39227 Mix4_InSol_Tio2_Reinj_1 6156 63993 39228 Mix4_TiO2_1_1 4586 Q14573 Q14573 Q14573 >sp|Q14573|ITPR3_HUMAN Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens GN=ITPR3 PE=1 SV=2 0.999115 32.7555 0.998599 28.5311 0.0128333 68.114 0 0 0.998196 27.4554 0.0375522 54.471 0.993252 24.4438 0.223978 29.72 0.999115 32.7555 0.106198 39.259 1 S TKGRVASFSIPGS CAMK2 0.042 0.0128333 68.114 _VApSFSIPGSSSR_ VAS(0.999)FS(0.001)IPGSSSR VAS(32.76)FS(-32.76)IPGS(-39.26)S(-39.26)S(-39.26)R 3 2 637.79247 0.09858 2088400 256300 0 0 1114100 0 386830 331120 1261 921 1598 1598 4850 5513 46518 28503 Mix4_TiO2_Reinj_1_1 2581 46518 28503 Mix4_TiO2_Reinj_1_1 2581 Q14643;Q14643-2;Q14643-6;Q14643-5;Q14643-7;Q14643-8;Q14643-3;Q14643-4 Q14643 Q14643 >sp|Q14643|ITPR1_HUMAN Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens GN=ITPR1 PE=1 SV=2;>sp|Q14643-2|ITPR1_HUMAN Isoform SI-SIIISIIAC of Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens GN=ITPR1;>sp|Q14643-6|ITPR1_HUMAN Isoform S 0.99992 40.9456 0.978332 16.5466 0.492372 16.547 0.99992 40.9456 0.0693589 40.946 0 0 0 0 1 S NAARRDSVLAASR AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.002856 0.0693589 40.946 _RDpSVLAASR_ RDS(1)VLAASR RDS(40.95)VLAAS(-40.95)R 3 2 527.75569 0.21671 255560 32570 0 0 222990 0 0 0 1262 922 1427 1427 456 519 4245 2546 Mix4_InSol_TiO2_1 1739 4245 2546 Mix4_InSol_TiO2_1 1739 Q14669 Q14669 Q14669 >sp|Q14669|TRIPC_HUMAN Probable E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens GN=TRIP12 PE=1 SV=1 0.978592 16.6026 0.899774 9.56609 0.0025262 85.346 0 0 0.978475 16.5776 0.00298743 120.38 0.978592 16.6026 0.00181989 127.59 0 0 1 S TAPTKTSPRNAKK CDK1;Proline-directed 0.0057 0.00181989 127.59 _AQTAPTKTpSPR_ AQTAPTKT(0.021)S(0.979)PR AQT(-124.06)APT(-49.34)KT(-16.6)S(16.6)PR 9 2 619.30046 0.15193 980950 73450 0 0 667900 0 239600 0 1263 922 312 312 5247 5973 50960 31238 Mix4_TiO2_1_5 5077 50960 31238 Mix4_TiO2_1_5 5077 Q14669 Q14669 Q14669 >sp|Q14669|TRIPC_HUMAN Probable E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens GN=TRIP12 PE=1 SV=1 0.868166 8.18636 0.868166 8.18636 0.0651605 46.655 0 0 0 0 1 S TKKRSESPPAELP 14-3-3 binding;CAMK2;PKA;Proline-directed 0.0001701 0.0651605 46.655 _SEpSPPAELPSLR_ S(0.132)ES(0.868)PPAELPSLR S(-8.19)ES(8.19)PPAELPS(-46.66)LR 3 2 681.81868 0.43481 55124 55124 0 0 0 0 0 0 1264 923 709 709 4842;4843 5502;5503 46300 28319 Mix4_TiO2_Reinj_1_5 4528 46329 28334 Mix4_TiO2_Reinj_1_5 4196 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.999738 35.8135 0.995004 23.0162 0.000230533 111.92 0.994738 22.7804 0.00331901 91.004 0.999738 35.8135 3.14349E-06 145.74 0.801501 7.64922 0.454445 15.972 0.993596 21.9104 0.000209402 112.65 0.996702 24.8137 0.0258528 58.906 1 S SGSRRDSLTGSSD AURORA;AURORA-1;AURORA-A;CAMK2;CK1;GSK3;PKA;PKA/AKT 0.00111111 3.14349E-06 145.74 _RDpSLTGSSDLYK_ RDS(1)LTGSSDLYK RDS(35.81)LT(-35.81)GS(-75.27)S(-82.48)DLY(-84.2)K 3 3 474.54846 -0.20012 19472000 3487400 125450 0 13317000 19084 1401800 1121500 1265 923 713 713 4842;4843 5502;5503 46319 28323 Mix4_InSol_TiO2_2 3440 46329 28334 Mix4_TiO2_Reinj_1_5 4196 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.328539 0 0.0229083 -15.8655 0.000230533 111.92 1.97512E-06 -57.0212 0.00331901 91.004 0.154427 -3.93671 3.14349E-06 145.74 0.0202612 -15.9724 0.454445 15.972 0.328539 0 0.000209402 112.65 0.141355 -7.15792 0.0258528 58.906 1 S RDSLTGSSDLYKR CK1;NEK6 0.076 3.14349E-06 145.74 _RDSLTGpSSDLYKR_ RDS(0.098)LT(0.244)GS(0.329)S(0.329)DLYKR RDS(-5.23)LT(-1.29)GS(0)S(0)DLY(-28.6)KR 7 2 789.3696 0.31744 0 0 0 0 0 0 0 0 1266 923 714 714 4842;4843 5502;5503 46319 28323 Mix4_InSol_TiO2_2 3440 46329 28334 Mix4_TiO2_Reinj_1_5 4196 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.328539 0 0.0494301 -12.6097 0.000230533 111.92 1.56373E-05 -48.0355 0.00331901 91.004 0.154427 -3.93671 3.14349E-06 145.74 0.137715 -7.64922 0.454445 15.972 0.328539 0 0.000209402 112.65 0.0331436 -13.7287 0.0258528 58.906 1 S DSLTGSSDLYKRT 3.14349E-06 145.74 _RDSLTGpSSDLYKR_ RDS(0.098)LT(0.244)GS(0.329)S(0.329)DLYKR RDS(-5.23)LT(-1.29)GS(0)S(0)DLY(-28.6)KR 8 2 789.3696 0.31744 0 0 0 0 0 0 0 0 1267 923 209 209 4984 5666 48069 29400 Mix4_TiO2_Reinj_1_6 4995 48068 29399 Mix4_TiO2_Reinj_1_5 5907 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.999963 44.2743 0.999906 40.2568 3.48687E-10 125.14 0.829209 6.87352 0.321388 37.234 0.999963 44.2743 5.5273E-16 151.49 0 0 0.999763 36.2497 0.000832703 84.652 0.999277 31.4057 0.000231203 94.95 1 S EVNSVLSPRSESG CDK1;CK1;ERK/MAPK;Proline-directed 0.0034 5.5273E-16 151.49 _RPGQSFHVNSEVNSVLpSPR_ RPGQSFHVNSEVNSVLS(1)PR RPGQS(-113.31)FHVNS(-75.58)EVNS(-44.27)VLS(44.27)PR 17 3 730.68657 0.045031 3986000 273680 33701 0 3431600 0 134360 112650 1268 923 803 803 5123 5828 49572 30282 Mix4_InSol_TiO2_1 8386 49573 30283 Mix4_TiO2_1_5 7052 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.459903 2.52495 1.18636E-05 -46.4931 5.22718E-11 132.84 0.000343577 -34.5206 6.70527E-07 111.41 0.459903 2.52495 1.09821 19.654 0 0 1 S SASSASSLFSPSS CK1 0.081 5.22718E-11 132.84 _SASSASpSLFSPSSTLFSSSR_ S(0.035)AS(0.04)S(0.04)AS(0.011)S(0.46)LFS(0.257)PS(0.072)S(0.056)T(0.014)LFS(0.005)S(0.005)S(0.005)R S(-11.24)AS(-10.6)S(-10.6)AS(-16.21)S(2.52)LFS(-2.52)PS(-8.06)S(-9.15)T(-15.05)LFS(-19.65)S(-19.65)S(-19.65)R 7 2 1036.9622 -0.41014 0 0 0 0 0 0 0 0 1269 923 806 806 5123 5828 49574 30284 Mix4_TiO2_Reinj_1_5 7838 49573 30283 Mix4_TiO2_1_5 7052 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.972925 16.5239 0.372691 -1.52179 5.22718E-11 132.84 0.972925 16.5239 6.70527E-07 111.41 0.257141 -2.52495 1.09821 19.654 0 0 1 S SASSLFSPSSTLF CK1;Proline-directed 0.05 5.22718E-11 132.84 _SASSASSLFpSPSSTLFSSSR_ SASSASSLFS(0.973)PS(0.022)S(0.004)T(0.001)LFSSSR S(-49.89)AS(-48.97)S(-48.97)AS(-33.51)S(-34.52)LFS(16.52)PS(-16.52)S(-23.99)T(-31.33)LFS(-74.03)S(-99.71)S(-105.16)R 10 2 1036.9622 0.33176 299330 0 0 0 299330 0 0 0 1270 923 808 808 5123 5828 49573 30283 Mix4_TiO2_1_5 7052 49573 30283 Mix4_TiO2_1_5 7052 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.529088 1.52179 0.529088 1.52179 5.22718E-11 132.84 0.0216617 -16.5239 6.70527E-07 111.41 0.0718976 -8.05952 1.09821 19.654 0 0 1 S SSLFSPSSTLFSS 5.22718E-11 132.84 _SASSASSLFSPpSSTLFSSSR_ SASSASSLFS(0.373)PS(0.529)S(0.093)T(0.005)LFSSSR S(-66.08)AS(-57.87)S(-65.79)AS(-45.25)S(-46.49)LFS(-1.52)PS(1.52)S(-7.55)T(-20.13)LFS(-71.92)S(-88.89)S(-105.67)R 12 2 1036.9622 0.31076 77415 77415 0 0 0 0 0 0 1271 923 227 227 5241;5242 5964;5965;5966 50856 31164 Mix4_TiO2_Reinj_1_5 8634 50843 31155 Mix4_TiO2_1_5 8347 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.331607 0 0.322868 0 3.28448E-46 213.55 0.331607 0 9.10263E-35 186.93 1 S MVEYVLSSSPGDS 3.28448E-46 213.55 _SESGGLGVSMVEYVLpSSSPGDSCLRK_ SESGGLGVSMVEY(0.003)VLS(0.332)S(0.332)S(0.332)PGDS(0.003)CLRK S(-81.85)ES(-76.88)GGLGVS(-41.8)MVEY(-21.09)VLS(0)S(0)S(0)PGDS(-21.09)CLRK 16 3 927.75388 -0.15213 0 0 0 0 0 0 0 0 1272 923 228 228 5241;5242 5964;5965;5966 50856 31164 Mix4_TiO2_Reinj_1_5 8634 50843 31155 Mix4_TiO2_1_5 8347 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.331607 0 0.322868 0 3.28448E-46 213.55 0.331607 0 9.10263E-35 186.93 1 S VEYVLSSSPGDSC 3.28448E-46 213.55 _SESGGLGVSMVEYVLpSSSPGDSCLRK_ SESGGLGVSMVEY(0.003)VLS(0.332)S(0.332)S(0.332)PGDS(0.003)CLRK S(-81.85)ES(-76.88)GGLGVS(-41.8)MVEY(-21.09)VLS(0)S(0)S(0)PGDS(-21.09)CLRK 17 3 927.75388 -0.15213 0 0 0 0 0 0 0 0 1273 923 229 229 5241;5242 5964;5965;5966 50846 31158 Mix4_TiO2_Reinj_1_5 8902 50843 31155 Mix4_TiO2_1_5 8347 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.997877 26.8346 0.99755 26.1534 3.28448E-46 213.55 0.997877 26.8346 9.10263E-35 186.93 1 S EYVLSSSPGDSCL CK2;GSK3;NEK6;Polo box;Proline-directed 0.00405 3.28448E-46 213.55 _SESGGLGVSMVEYVLSSpSPGDSCLR_ SESGGLGVSMVEYVLSS(0.002)S(0.998)PGDSCLR S(-157.29)ES(-156.73)GGLGVS(-132.7)MVEY(-123.8)VLS(-52.44)S(-26.83)S(26.83)PGDS(-43.09)CLR 18 3 885.05556 0.17701 4223900 684130 0 0 3539800 0 0 0 1274 925 22 22 574 658 5431 3249 Mix4_TiO2_2_4 4892 5431 3249 Mix4_TiO2_2_4 4892 Q14677 Q14677 Q14677 >sp|Q14677|EPN4_HUMAN Clathrin interactor 1 OS=Homo sapiens GN=CLINT1 PE=1 SV=1 0.903703 9.23525 0.903703 9.23525 0.0769409 52.331 2 S NVVMNYSEIESKV CK2;GSK3 0.081 0.0769409 52.331 _ATNVVMNpYpSEIESKVR_ AT(0.193)NVVMNY(0.904)S(0.904)EIESKVR AT(-9.24)NVVMNY(9.24)S(9.24)EIES(-52.33)KVR 9 3 667.29138 -0.000992 47605 0 47605 0 0 0 0 0 1275 926 505 505 687;5820 788;789;6636;6637 57390 34951 Mix4_InSol_Tio2_Reinj_1 6201 57386 34947 Mix4_InSol_TiO2_1 6263 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 1 114.133 0.999999 61.4073 0.0239497 61.407 0.999997 54.9081 0.0624591 54.908 1 146.394 2.00677E-12 146.39 1 114.133 2.83636E-06 114.13 1 S PERRCRSVELDLN CAMK2 0.002856 2.00677E-12 146.39 _pSVELDLNQAHMEETPK_ S(1)VELDLNQAHMEETPK S(114.13)VELDLNQAHMEET(-114.13)PK 1 2 960.92408 0.4504 2461600 294060 0 0 555580 0 879190 732790 1276 926 335 335 3733 4210 35213 21786 Mix4_TiO2_1_3 6092 35213 21786 Mix4_TiO2_1_3 6092 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 0.499998 0 0.499998 0 3.20596E-15 138.44 0 0 0 0 0 0 1 S PVRLRLSSFSCGQ NEK6;PKA 0.042 3.20596E-15 138.44 _LpSSFSCGQASATPFTDIK_ LS(0.5)S(0.5)FSCGQASATPFTDIK LS(0)S(0)FS(-50.17)CGQAS(-80.99)AT(-90.44)PFT(-110.87)DIK 2 2 998.93973 -0.01747 354480 354480 0 0 0 0 0 0 1277 926 336 336 3733 4210 35213 21786 Mix4_TiO2_1_3 6092 35213 21786 Mix4_TiO2_1_3 6092 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 0.499998 0 0.499998 0 3.20596E-15 138.44 0 0 0 0 0 0 1 S VRLRLSSFSCGQA CAMK2;PKA/AKT 0.001764 3.20596E-15 138.44 _LpSSFSCGQASATPFTDIK_ LS(0.5)S(0.5)FSCGQASATPFTDIK LS(0)S(0)FS(-50.17)CGQAS(-80.99)AT(-90.44)PFT(-110.87)DIK 3 2 998.93973 -0.01747 354480 354480 0 0 0 0 0 0 1278 926 356 356 5511 6274 53778 32888 Mix4_TiO2_Reinj_1_3 6305 53778 32888 Mix4_TiO2_Reinj_1_3 6305 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 1 84.5313 1 84.2919 6.62578E-22 204.98 0 0 1 84.5313 6.62571E-22 204.98 0 0 0.999999 59.8387 2.62077E-11 160.47 0.999999 61.9301 2.22648E-10 156.34 1 S IKSNNWSLEDVTA CK1;CK2 0.117 6.62571E-22 204.98 _SNNWpSLEDVTASDK_ SNNWS(1)LEDVTASDK S(-84.53)NNWS(84.53)LEDVT(-106.81)AS(-164.82)DK 5 2 823.34071 0.0094537 16522000 40.149 4809300 0 0 11478000 0 165160 69094 1279 926 529 529 6401 7323 64663 39677 Mix4_TiO2_Reinj_1_5 5069 64653 39663 Mix4_InSol_Tio2_Reinj_1 5312 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 1 49.4755 1 36.5164 0.0692627 62.717 1 35.3242 0.228709 35.324 1 49.4755 0.0692627 62.717 0 0 1 55.5183 0.0960591 55.518 1 37.5923 0.0692627 62.718 1 S GAKVFGSLERGLD 0.0692627 62.718 _VFGpSLER_ VFGS(1)LER VFGS(49.48)LER 4 2 444.20477 -0.0025719 26307000 4137500 390880 0 16181000 0 3305500 2292100 1280 927 624 624 4068 4635 38566 23660 Mix4_TiO2_Reinj_1_5 5387 38566 23660 Mix4_TiO2_Reinj_1_5 5387 Q14694-2;Q14694-3;Q14694 Q14694-2 Q14694-2 >sp|Q14694-2|UBP10_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens GN=USP10;>sp|Q14694-3|UBP10_HUMAN Isoform 3 of Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens GN=USP10;>sp|Q14694|UBP10_HUMAN Ubiquitin carboxyl-termin 1 92.6317 1 97.0966 5.33787E-08 115.52 1 92.6317 1.25249E-11 118.66 0.999922 41.0609 0.348614 47.532 0.999578 33.7434 0.997421 33.743 1 S EEQGEGSEDEWEQ CK2 0.117 1.25249E-11 118.66 _NHSVNEEEQEEQGEGpSEDEWEQVGPR_ NHSVNEEEQEEQGEGS(1)EDEWEQVGPR NHS(-92.63)VNEEEQEEQGEGS(92.63)EDEWEQVGPR 16 3 1036.4093 0.14925 1045000 210760 0 0 648710 0 94584 90996 1281 932 182 182 3498 3951 33037 20442 Mix4_TiO2_Reinj_1_4 2567 33037 20442 Mix4_TiO2_Reinj_1_4 2567 Q14739 Q14739 Q14739 >sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 1 48.6524 0 0 1 48.6524 0.0419934 48.652 1 S KLKEIDSKEEKYV CK2 0.117 0.0419934 48.652 _LKEIDpSKEEK_ LKEIDS(1)KEEK LKEIDS(48.65)KEEK 6 2 649.81561 0.61224 103470 0 0 0 103470 0 0 0 1282 932 97 97 5034;5035;5113;5114 5725;5726;5727;5816;5818 48616 29714 Mix4_InSol_TiO2_2 1517 49455 30194 Mix4_InSol_TiO2_1 2675 Q14739 Q14739 Q14739 >sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 0.930802 11.4877 0.486396 0 0.000995448 101.65 0.876138 8.49665 0.0159408 62.501 0.766745 5.17546 0.000973172 102.07 0 0 0.930802 11.4877 9.66703E-10 155.14 0.86811 8.18636 7.16827E-08 136.76 1 S PKSARRSASASHQ CK1;GSK3;PKA 0.042 9.66703E-10 155.14 _RpSASASHQADIK_ RS(0.931)AS(0.066)AS(0.003)HQADIK RS(11.49)AS(-11.49)AS(-24.75)HQADIK 2 2 675.81172 -0.14031 2012000 71.886 0 298050 0 75683 0 416920 1221400 1283 932 99 99 5034;5035;5113;5114 5725;5726;5727;5816;5818 48665 29758 Mix4_InSol_TiO2_1 2619 49455 30194 Mix4_InSol_TiO2_1 2675 Q14739 Q14739 Q14739 >sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 0.983722 17.9164 0.938789 12.2386 0.000995448 101.65 0.795657 6.13137 0.0159408 62.501 0.98141 18.4594 0.000973172 102.07 0 0 0.983722 17.9164 9.66703E-10 155.14 0.974661 16.2814 7.16827E-08 136.76 1 S SARRSASASHQAD CAMK2;PKA/AKT 0.00111111 9.66703E-10 155.14 _RSApSASHQADIKEAR_ RSAS(0.984)AS(0.016)HQADIKEAR RS(-34.08)AS(17.92)AS(-17.92)HQADIKEAR 4 2 853.90213 0.073866 61659000 2202.9 4945600 51881 0 39630000 0 10176000 6855700 1284 932 101 101 5034;5035;5113;5114 5725;5726;5727;5816;5818 49428 30180 Mix4_TiO2_Reinj_1_3 1956 49455 30194 Mix4_InSol_TiO2_1 2675 Q14739 Q14739 Q14739 >sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 0.499981 0 0.324707 -0.333032 0.000995448 101.65 0.0479767 -10.9198 0.0159408 62.501 0.499981 0 0.000973172 102.07 0 0 0.389818 0 9.66703E-10 155.14 0.308396 -0.943248 7.16827E-08 136.76 1 S RRSASASHQADIK CK1 0.143 9.66703E-10 155.14 _SApSASHQADIK_ SAS(0.5)AS(0.5)HQADIK S(-41.16)AS(0)AS(0)HQADIK 5 3 398.8432 0.32153 73187 2.6148 0 0 0 73187 0 0 0 1285 932 84 84 5682 6470;6471 55666 34121 Mix4_TiO2_Reinj_1_4 1321 55666 34121 Mix4_TiO2_Reinj_1_4 1321 Q14739 Q14739 Q14739 >sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 0.989822 19.8788 0.825746 6.75663 0.784344 6.7566 0 0 0.989822 19.8788 0.00468204 69.465 0.972336 15.4589 0.013118 58.733 0.958204 13.6032 0.17568 33.362 1 S SRSRSRSRSPGRP CAMK2;CK1;PKA/AKT 0.00111111 0.00468204 69.465 _pSRSPGRPPK_ S(0.99)RS(0.01)PGRPPK S(19.88)RS(-19.88)PGRPPK 1 2 531.26622 0.35343 10946000 574.55 54515 0 0 7578800 0 1869700 1442900 1286 933 467 467 4425 5034 42114 25948 Mix4_TiO2_Reinj_1_6 2254 42113 25947 Mix4_TiO2_Reinj_1_1 2191 Q14746 Q14746 Q14746 >sp|Q14746|COG2_HUMAN Conserved oligomeric Golgi complex subunit 2 OS=Homo sapiens GN=COG2 PE=1 SV=1 1 33.4596 1 28.9473 0.233519 28.947 1 33.4596 0.12735 37.546 2 S LSLRPISNESPKE CAMK2 0.042 0.12735 37.546 _PIpSNEpSPKEIKK_ PIS(1)NES(1)PKEIKK PIS(33.46)NES(33.46)PKEIKK 3 2 765.35425 0.048724 1755400 0 323960 0 1431400 0 0 0 1287 933 470 470 4425 5034 42114 25948 Mix4_TiO2_Reinj_1_6 2254 42113 25947 Mix4_TiO2_Reinj_1_1 2191 Q14746 Q14746 Q14746 >sp|Q14746|COG2_HUMAN Conserved oligomeric Golgi complex subunit 2 OS=Homo sapiens GN=COG2 PE=1 SV=1 1 33.4596 1 28.9473 0.233519 28.947 1 33.4596 0.12735 37.546 2 S RPISNESPKEIKK CDK1;CK1;CK2;Proline-directed 0.0057 0.12735 37.546 _PIpSNEpSPKEIKK_ PIS(1)NES(1)PKEIKK PIS(33.46)NES(33.46)PKEIKK 6 2 765.35425 0.048724 1755400 0 323960 0 1431400 0 0 0 1288 936 1757 1757 6180 7057 61224 37091 Mix4_TiO2_1_1 3398 61225 37092 Mix4_TiO2_Reinj_1_1 3905 Q14980;Q14980-2 Q14980 Q14980 >sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 OS=Homo sapiens GN=NUMA1 PE=1 SV=2;>sp|Q14980-2|NUMA1_HUMAN Isoform 2 of Nuclear mitotic apparatus protein 1 OS=Homo sapiens GN=NUMA1 0.998994 30.0657 0.998994 30.0657 0.0001575 96.185 0.916779 10.4207 3.38953E-10 125.48 0 0 0 0 1 S VPGEPASPISQRL ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.38953E-10 125.48 _TQPDGTSVPGEPApSPISQR_ TQPDGTSVPGEPAS(0.999)PIS(0.001)QR T(-66.94)QPDGT(-52.64)S(-47.77)VPGEPAS(30.07)PIS(-30.07)QR 14 2 1002.4571 0.114 128710 35593 0 0 93121 0 0 0 1289 937 1121 1121 4245;4246 4833;4834 40440 24911 Mix4_TiO2_1_5 6063 40440 24911 Mix4_TiO2_1_5 6063 Q14997;Q14997-2;Q14997-3 Q14997 Q14997 >sp|Q14997|PSME4_HUMAN Proteasome activator complex subunit 4 OS=Homo sapiens GN=PSME4 PE=1 SV=2;>sp|Q14997-2|PSME4_HUMAN Isoform 2 of Proteasome activator complex subunit 4 OS=Homo sapiens GN=PSME4;>sp|Q14997-3|PSME4_HUMAN Isoform 3 of Proteasome activato 1 78.1551 1 78.1551 0.0058785 78.155 1 68.6261 0.01392 68.626 1 S INQILLSPEKIKE CDK1;CDK2;Proline-directed 0.0057 0.0058785 78.155 _NPSINQILLpSPEK_ NPSINQILLS(1)PEK NPS(-78.16)INQILLS(78.16)PEK 10 2 766.88964 0.18012 391790 57237 0 0 334560 0 0 0 1290 938 1128 1128 5344 6085 51902 31764 Mix4_TiO2_Reinj_1_5 5117 51902 31764 Mix4_TiO2_Reinj_1_5 5117 Q14999 Q14999 Q14999 >sp|Q14999|CUL7_HUMAN Cullin-7 OS=Homo sapiens GN=CUL7 PE=1 SV=2 0.929816 11.2218 0 0 0.929816 11.2218 0.00548927 64.927 1 S NRSHDWSSLATRG CK1 0.143 0.00548927 64.927 _SHDWpSSLATR_ SHDWS(0.93)S(0.07)LATR S(-64.93)HDWS(11.22)S(-11.22)LAT(-55.88)R 5 2 620.26133 0.37302 126630 0 0 0 126630 0 0 0 1291 939 757 757 1924 2175 17663 10556 Mix4_TiO2_Reinj_1_5 8009 17663 10556 Mix4_TiO2_Reinj_1_5 8009 Q14C86-6;Q14C86;Q14C86-2;Q14C86-5;Q14C86-4;Q14C86-3 Q14C86-6 Q14C86-6 >sp|Q14C86-6|GAPD1_HUMAN Isoform 6 of GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1;>sp|Q14C86|GAPD1_HUMAN GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1 PE=1 SV=2;>sp|Q14 0.817435 6.51275 0.428922 -0.307033 1.28482 37.251 0.817435 6.51275 0.0169044 74.952 2 S TDVREVSSRPSTP CAMK2;GSK3;PKC 0.001764 0.0169044 74.952 _EVpSpSRPSTPGLSVVSGISATSEDIPNKIEDLR_ EVS(0.817)S(0.394)RPS(0.394)T(0.394)PGLSVVSGISATSEDIPNKIEDLR EVS(6.51)S(0)RPS(0)T(0)PGLS(-32.33)VVS(-53.41)GIS(-71.47)AT(-71.78)S(-71.63)EDIPNKIEDLR 3 4 875.91939 0.39948 573800 0 0 0 573800 0 0 0 1292 939 758 758 1924 2175 17662 10555 Mix4_TiO2_Reinj_1_1 7580 17663 10556 Mix4_TiO2_Reinj_1_5 8009 Q14C86-6;Q14C86;Q14C86-2;Q14C86-5;Q14C86-4;Q14C86-3 Q14C86-6 Q14C86-6 >sp|Q14C86-6|GAPD1_HUMAN Isoform 6 of GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1;>sp|Q14C86|GAPD1_HUMAN GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1 PE=1 SV=2;>sp|Q14 0.497748 0 0.45238 0.307033 1.28482 37.251 0.497748 0 0.0169044 74.952 2 S DVREVSSRPSTPG 0.0169044 74.952 _EVpSpSRPSTPGLSVVSGISATSEDIPNKIEDLR_ EVS(0.498)S(0.498)RPS(0.498)T(0.498)PGLS(0.008)VVS(0.001)GISATSEDIPNKIEDLR EVS(0)S(0)RPS(0)T(0)PGLS(-18.66)VVS(-30.95)GIS(-40.94)AT(-44.95)S(-44.95)EDIPNKIEDLR 4 4 875.91939 0.42527 0 0 0 0 0 0 0 0 1293 939 761 761 1924 2175 17661 10554 Mix4_TiO2_1_5 7297 17663 10556 Mix4_TiO2_Reinj_1_5 8009 Q14C86-6;Q14C86;Q14C86-2;Q14C86-5;Q14C86-4;Q14C86-3 Q14C86-6 Q14C86-6 >sp|Q14C86-6|GAPD1_HUMAN Isoform 6 of GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1;>sp|Q14C86|GAPD1_HUMAN GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1 PE=1 SV=2;>sp|Q14 0.682431 7.07459 0.682431 7.07459 1.28482 37.251 0.497748 0 0.0169044 74.952 2 S EVSSRPSTPGLSV CK1;PKA 0.042 0.0169044 74.952 _EVSSRPpSpTPGLSVVSGISATSEDIPNKIEDLR_ EVS(0.284)S(0.284)RPS(0.682)T(0.682)PGLS(0.058)VVS(0.005)GIS(0.002)AT(0.001)S(0.001)EDIPNKIEDLR EVS(-7.07)S(-7.07)RPS(7.07)T(7.07)PGLS(-13.18)VVS(-25.54)GIS(-30.94)AT(-35.33)S(-35.33)EDIPNKIEDLR 7 4 875.91939 0.33218 202750 202750 0 0 0 0 0 0 1294 939 930 930 5686 6476 55693 34134 Mix4_TiO2_1_1 3027 55694 34135 Mix4_TiO2_Reinj_1_1 3554 Q14C86-6;Q14C86;Q14C86-2;Q14C86-5;Q14C86-4;Q14C86-3 Q14C86-6 Q14C86-6 >sp|Q14C86-6|GAPD1_HUMAN Isoform 6 of GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1;>sp|Q14C86|GAPD1_HUMAN GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1 PE=1 SV=2;>sp|Q14 0.758283 5.1028 0.758283 5.1028 0.0639626 44.494 0.596228 1.70875 0.0383699 52.084 0 0 1 S LVRSRSSDIVSSV CK1;GSK3;PKA 0.042 0.0383699 52.084 _SRSpSDIVSSVR_ S(0.007)RS(0.234)S(0.758)DIVSSVR S(-20.06)RS(-5.1)S(5.1)DIVS(-44.49)S(-44.49)VR 4 2 636.80082 0.031353 117750 19411 0 0 98334 0 0 0 1295 940 691 691 2900 3303 27762 17300 Mix4_TiO2_Reinj_1_5 5799 27757 17294 Mix4_TiO2_1_3 4983 Q14CX7;Q14CX7-2 Q14CX7 Q14CX7 >sp|Q14CX7|NAA25_HUMAN N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens GN=NAA25 PE=1 SV=1;>sp|Q14CX7-2|NAA25_HUMAN Isoform 2 of N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens GN=NAA25 0.994626 22.6735 0.991136 20.4849 0.0806165 58.228 0.975471 15.9953 0.161723 43.996 0.994626 22.6735 0.139383 47.916 0 0 0.97253 15.4904 0.338018 22.933 0.991601 20.7208 0.338362 22.894 1 S LWLRIRSLTLRLI CAMK2 0.042 0.0806165 58.228 _IRpSLTLR_ IRS(0.995)LT(0.005)LR IRS(22.67)LT(-22.67)LR 3 2 469.76278 -0.45895 3038100 854250 148360 0 252590 0 143460 1639500 1296 941 27 27 2258 2554 20850 12794 Mix4_TiO2_Reinj_1_5 1190 20850 12794 Mix4_TiO2_Reinj_1_5 1190 Q15003 Q15003 Q15003 >sp|Q15003|CND2_HUMAN Condensin complex subunit 2 OS=Homo sapiens GN=NCAPH PE=1 SV=3 0.93335 11.5223 0 0 0.93335 11.5223 0.00428265 87.545 0.0585567 -12.0286 0.00707736 78.51 0.119441 -7.4728 0.585405 10.281 1 S GHPHSASSPSERV 0.00428265 87.545 _GHPHSApSSPSER_ GHPHS(0.001)AS(0.933)S(0.066)PSER GHPHS(-30.45)AS(11.52)S(-11.52)PS(-41.15)ER 7 2 664.7726 0.068814 450940 0 0 0 450940 0 0 0 1297 941 28 28 2258 2554 20847 12790 Mix4_InSol_TiO2_1 1363 20850 12794 Mix4_TiO2_Reinj_1_5 1190 Q15003 Q15003 Q15003 >sp|Q15003|CND2_HUMAN Condensin complex subunit 2 OS=Homo sapiens GN=NCAPH PE=1 SV=3 0.934183 12.0286 0 0 0.065738 -11.5223 0.00428265 87.545 0.934183 12.0286 0.00707736 78.51 0.667475 7.28825 0.585405 10.281 1 S HPHSASSPSERVF CK1;CK2;Polo box;Proline-directed 0.00405 0.00428265 87.545 _GHPHSASpSPSER_ GHPHSAS(0.059)S(0.934)PS(0.007)ER GHPHS(-44.71)AS(-12.03)S(12.03)PS(-21.11)ER 8 2 664.7726 -0.19624 178670 0 0 0 0 0 95844 82829 1298 944 253 253 2948 3355 28130 17486 Mix4_TiO2_Reinj_1_4 5613 28130 17486 Mix4_TiO2_Reinj_1_4 5613 Q15019-2;Q15019 Q15019-2 Q15019-2 >sp|Q15019-2|SEPT2_HUMAN Isoform 2 of Septin-2 OS=Homo sapiens GN=SEPT2;>sp|Q15019|SEPT2_HUMAN Septin-2 OS=Homo sapiens GN=SEPT2 PE=1 SV=1 1 79.8646 1 78.6014 1.22665E-07 116.89 1 79.8646 4.74251E-11 133.27 0.999924 41.2342 0.00890839 70.217 0.999951 45.3158 0.0607303 55.436 1 S HLPDAESDEDEDF CK2 0.117 4.74251E-11 133.27 _IYHLPDAEpSDEDEDFKEQTR_ IYHLPDAES(1)DEDEDFKEQTR IY(-79.86)HLPDAES(79.86)DEDEDFKEQT(-114.02)R 9 3 839.68663 0.30737 2325800 397420 0 0 1631400 0 155070 141870 1299 945 8 8 550 627;629 5212 3179 Mix4_TiO2_Reinj_1_5 2940 5212 3179 Mix4_TiO2_Reinj_1_5 2940 Q15020;Q15020-2;Q15020-3 Q15020 Q15020 >sp|Q15020|SART3_HUMAN Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens GN=SART3 PE=1 SV=1;>sp|Q15020-2|SART3_HUMAN Isoform 2 of Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens GN=SART3;>sp|Q15020-3|SART3_HUMA 0.999375 32.0404 0.999107 30.4889 9.4499E-16 159.79 0 0 0.999375 32.0404 4.10422E-20 186.72 0.00025088 -36.004 1.72702E-16 172.98 0.000202884 -36.9266 3.20223E-20 188.59 2 S ATAAETSASEPEA CK2 0.117 4.10422E-20 186.72 _(ac)ATAAETpSApSEPEAESK_ ATAAET(0.001)S(0.999)AS(1)EPEAESK AT(-95.64)AAET(-32.04)S(32.04)AS(78.26)EPEAES(-121.79)K 7 2 890.83173 -0.31971 769270 1.3045 160220 0 0 609050 0 0 0 1300 945 10 10 550 627;629 5185 3171 Mix4_TiO2_Reinj_1_5 3290 5184 3168 Mix4_TiO2_1_5 2645 Q15020;Q15020-2;Q15020-3 Q15020 Q15020 >sp|Q15020|SART3_HUMAN Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens GN=SART3 PE=1 SV=1;>sp|Q15020-2|SART3_HUMAN Isoform 2 of Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens GN=SART3;>sp|Q15020-3|SART3_HUMA 0.999974 46.6962 0.99955 33.5467 1.32578E-25 195.77 0 0 0.999974 46.6962 4.69745E-16 167.91 0.999699 36.004 1.72702E-16 172.98 0.999797 36.9266 3.20223E-20 188.59 1 S AAETSASEPEAES CK2 0.117 1.32578E-25 195.77 _(ac)ATAAETSApSEPEAESK_ ATAAETSAS(1)EPEAESK AT(-104.83)AAET(-53.65)S(-46.7)AS(46.7)EPEAES(-72.42)K 9 2 850.84856 0.23333 2574500 4.3658 294940 0 0 1601200 0 364080 314260 1301 946 1330 1330 6780 7757 68732 42161 Mix4_TiO2_Reinj_1_5 6297 68730 42159 Mix4_TiO2_1_5 5191 Q15021 Q15021 Q15021 >sp|Q15021|CND1_HUMAN Condensin complex subunit 1 OS=Homo sapiens GN=NCAPD2 PE=1 SV=3 0.332872 0 0.214382 -4.98069 1.08264E-21 171.89 0 0 0.332872 0 0.0897001 51.747 4.94023E-06 -53.0595 2.94862E-21 164.85 0.041908 -13.5581 0.000277614 94.158 1 S RYQPLASTASDND 1.08264E-21 171.89 _YQPLApSTASDNDFVTPEPR_ Y(0.001)QPLAS(0.333)T(0.333)AS(0.333)DNDFVTPEPR Y(-23.82)QPLAS(0)T(0)AS(0)DNDFVT(-49.04)PEPR 6 3 729.99132 0.07662 0 0 0 0 0 0 0 0 0 1302 946 1333 1333 6780 7757 68731 42160 Mix4_TiO2_1_5 5455 68730 42159 Mix4_TiO2_1_5 5191 Q15021 Q15021 Q15021 >sp|Q15021|CND1_HUMAN Condensin complex subunit 1 OS=Homo sapiens GN=NCAPD2 PE=1 SV=3 0.999732 35.9271 0.999732 35.9271 1.08264E-21 171.89 0 0 0.332872 0 0.0897001 51.747 0.999294 32.2509 2.94862E-21 164.85 0.996458 27.6577 0.000277614 94.158 1 S PLASTASDNDFVT CK1;CK2 0.081 1.08264E-21 171.89 _YQPLASTApSDNDFVTPEPR_ YQPLASTAS(1)DNDFVTPEPR Y(-128.98)QPLAS(-49.03)T(-35.93)AS(35.93)DNDFVT(-70.07)PEPR 9 2 1094.4833 0.17193 953250 6.2211 501710 0 0 0 0 245910 205630 1303 947 19 19 3831 4330 36353 22444 Mix4_TiO2_Reinj_1_5 8673 36351 22442 Mix4_TiO2_1_5 8169 Q15029 Q15029 Q15029 >sp|Q15029|U5S1_HUMAN 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens GN=EFTUD2 PE=1 SV=1 1 89.664 1 91.1261 1.68177E-18 149.97 1 89.664 2.13404E-18 148.16 1 S IGPELDSDEDDDE CK2 0.117 1.68177E-18 149.97 _(ac)M(ox)DTDLYDEFGNYIGPELDpSDEDDDELGR_ MDTDLYDEFGNYIGPELDS(1)DEDDDELGR MDT(-148.16)DLY(-133.24)DEFGNY(-89.66)IGPELDS(89.66)DEDDDELGR 19 3 1126.1009 1.121 1318600 306420 0 0 1012100 0 0 0 1304 948 5 5 32 41;42 386 236 Mix4_TiO2_Reinj_1_5 8907 386 236 Mix4_TiO2_Reinj_1_5 8907 Q15042 Q15042 Q15042 >sp|Q15042|RB3GP_HUMAN Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens GN=RAB3GAP1 PE=1 SV=3 0.999715 35.4436 0.449126 -0.886811 0.00017153 93.107 0.999715 35.4436 2.4618E-34 180.27 1 S __MAADSEPESEV CK2;GSK3 0.081 2.4618E-34 180.27 _AADpSEPESEVFEITDFTTASEWER_ AADS(1)EPESEVFEITDFTTASEWER AADS(35.44)EPES(-35.44)EVFEIT(-132.2)DFT(-165.16)T(-171.52)AS(-180.27)EWER 4 2 1413.5869 0.66433 2567300 0 0 0 2567300 0 0 0 1305 948 9 9 32 41;42 377 232 Mix4_TiO2_1_6 7076 386 236 Mix4_TiO2_Reinj_1_5 8907 Q15042 Q15042 Q15042 >sp|Q15042|RB3GP_HUMAN Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens GN=RAB3GAP1 PE=1 SV=3 0.550871 0.886811 0.550871 0.886811 0.00017153 93.107 0.10721 -9.20492 2.4618E-34 180.27 1 S ADSEPESEVFEIT CK1 0.143 2.4618E-34 180.27 _(ac)AADSEPEpSEVFEITDFTTASEWER_ AADS(0.449)EPES(0.551)EVFEITDFTTASEWER AADS(-0.89)EPES(0.89)EVFEIT(-52.44)DFT(-82.3)T(-89.04)AS(-93.11)EWER 8 2 1434.5922 0.90741 37108 37108 0 0 0 0 0 0 1306 949 307 307 6338 7247 63879 39136 Mix4_InSol_TiO2_1 4720 63879 39136 Mix4_InSol_TiO2_1 4720 Q15054 Q15054 Q15054 >sp|Q15054|DPOD3_HUMAN DNA polymerase delta subunit 3 OS=Homo sapiens GN=POLD3 PE=1 SV=2 0.999978 46.6028 0.999978 46.6028 0.00117813 91.452 0 0 1 S GKRVALSDDETKE CK2 0.117 0.00117813 91.452 _VALpSDDETKETENMR_ VALS(1)DDETKETENMR VALS(46.6)DDET(-46.6)KET(-80.27)ENMR 4 2 909.38479 -0.72685 50343 0 0 0 0 0 50343 0 1307 951 77 77 3639 4104 34296 21302 Mix4_TiO2_Reinj_1_5 1852 34294 21299 Mix4_InSol_Tio2_Reinj_1 2049 Q15061 Q15061 Q15061 >sp|Q15061|WDR43_HUMAN WD repeat-containing protein 43 OS=Homo sapiens GN=WDR43 PE=1 SV=3 1 44.9008 1 32.915 0.181937 32.915 1 44.9008 0.0567995 44.901 1 36.4263 0.132716 36.426 1 62.683 0.00739517 62.683 1 S RLQAKESPQRKKR CDK1;CDK2;Proline-directed 0.0057 0.00739517 62.683 _LQAKEpSPQR_ LQAKES(1)PQR LQAKES(44.9)PQR 6 2 568.77662 0.34715 503390 24103 0 0 166360 0 144950 167980 1308 953;954 1435;1298 1298 439;440 501;502 4145 2479 Mix4_InSol_Tio2_Reinj_1 3570 4138 2477 Mix4_TiO2_Reinj_1_1 3215 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 1 11.725 1 46.9735 0.0556024 46.973 0 0 1 75.1998 0.00480517 75.2 0 0 1 32.7295 0.269104 32.73 1 11.725 0.824248 11.725 1 S QLEPVASPAKKPK CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 0.00480517 75.2 _AQLEPVApSPAKKPK_ AQLEPVAS(1)PAKKPK AQLEPVAS(11.72)PAKKPK 8 2 772.41582 0.39459 536910 69710 0 0 319560 0 78641 68999 1309 953;954 4622;4485 4485 2552 2897 23893 14821 Mix4_InSol_Tio2_Reinj_1 5294 23892 14820 Mix4_InSol_TiO2_1 5380 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.823666 9.70475 8.958E-07 -60.4776 1.59648E-31 206.56 0 0 0.333296 0 6.4714E-22 174.57 0 0 0.104448 -9.33149 2.14962E-58 253.21 0.823666 9.70475 2.18002E-15 144.29 1 S SVSGSGSTAGSRT CK1;GSK3 0.081 2.14962E-58 253.21 _GYYSPYSVSGSGpSTAGSR_ GYYSPYSVSGSGS(0.824)T(0.088)AGS(0.088)R GY(-144.29)Y(-144.29)S(-144.29)PY(-134.96)S(-107.54)VS(-86.59)GS(-48.26)GS(9.7)T(-9.7)AGS(-9.7)R 13 2 931.88327 0.82198 32400 0 0 0 0 0 0 32400 1310 953;954 4626;4489 4489 2552 2897 23894 14823 Mix4_TiO2_1_1 3964 23892 14820 Mix4_InSol_TiO2_1 5380 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.99994 42.2746 0.99994 42.2746 1.59648E-31 206.56 0 0 0.333296 0 6.4714E-22 174.57 0 0 8.52018E-05 -40.216 2.14962E-58 253.21 0.0881609 -9.70475 2.18002E-15 144.29 1 S SGSTAGSRTGSRT CK1;GSK3 0.081 2.14962E-58 253.21 _GYYSPYSVSGSGSTAGpSR_ GYYSPYSVSGSGSTAGS(1)R GY(-206.56)Y(-206.56)S(-203.03)PY(-190.18)S(-154.76)VS(-131.08)GS(-81.78)GS(-60.48)T(-42.27)AGS(42.27)R 17 2 931.88327 0.019327 49615 49615 0 0 0 0 0 0 1311 953;954 4642;4505 4505 4889 5560 46961 28736 Mix4_TiO2_Reinj_1_1 5936 46961 28736 Mix4_TiO2_Reinj_1_1 5936 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.996589 25.9703 0 0 0 0 0.996589 25.9703 9.39353E-08 110.92 1 S AGSRRGSFDATGS AURORA;AURORA-A;CAMK2;CK1;PKA 0.004788 9.39353E-08 110.92 _RGpSFDATGSGFSM(ox)TFSSSSYSSSGYGR_ RGS(0.997)FDAT(0.003)GS(0.001)GFSMTFSSSSYSSSGYGR RGS(25.97)FDAT(-25.97)GS(-32.72)GFS(-34.51)MT(-53.76)FS(-92.36)S(-105.27)S(-110.92)S(-110.92)Y(-110.92)S(-110.92)S(-110.92)S(-110.92)GY(-110.92)GR 3 3 957.05175 0.12626 560810 0 0 0 560810 0 0 0 1312 953;954 720;583 583 5155 5869 49986 30555 Mix4_TiO2_Reinj_1_1 2572 49986 30555 Mix4_TiO2_Reinj_1_1 2572 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.999998 57.8809 0 0 0.999998 57.8809 0.00269297 83.49 0 0 1 S SDEGQLSPATRGA Proline-directed 0.05 0.00269297 83.49 _SDEGQLpSPATR_ SDEGQLS(1)PATR S(-76.67)DEGQLS(57.88)PAT(-57.88)R 7 2 620.76391 0.033434 74471 2.4421 0 0 0 74471 0 0 0 1313 953;954 4385;4248 4248 5759 6562 56625 34559 Mix4_TiO2_Reinj_2_1 3578 56622 34556 Mix4_TiO2_1_1 3975 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.461985 0.695933 0.112602 -8.57064 1.25184E-15 149.54 0.227131 0 0.673807 25.785 0.120971 -8.16043 8.26884E-10 119.52 0.461985 0.695933 0.814189 21.61 0.366473 0 5.93599E-06 101.44 0.351242 0 0.0068577 74.87 1 S GFRSRSSSVGSSS CK1;GSK3;PKA 0.042 1.25184E-15 149.54 _SpSSVGSSSSYPISPAVSR_ S(0.394)S(0.462)S(0.12)VGS(0.005)S(0.003)S(0.003)S(0.003)Y(0.003)PIS(0.003)PAVS(0.003)R S(-0.7)S(0.7)S(-5.84)VGS(-19.76)S(-21.61)S(-21.61)S(-21.61)Y(-21.61)PIS(-21.61)PAVS(-21.61)R 2 2 917.91457 0.13735 0 0 0 0 0 0 0 0 1314 953;954 4386;4249 4249 5759 6562 56622 34556 Mix4_TiO2_1_1 3975 56622 34556 Mix4_TiO2_1_1 3975 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.810232 8.57064 0.810232 8.57064 1.25184E-15 149.54 0.19081 -0.756751 0.673807 25.785 0.791999 8.16043 8.26884E-10 119.52 0.120417 -5.83939 0.814189 21.61 0.366473 0 5.93599E-06 101.44 0.351242 0 0.0068577 74.87 1 S FRSRSSSVGSSSS CAMK2;CK1;GSK3;PKA/AKT 0.001764 1.25184E-15 149.54 _SSpSVGSSSSYPISPAVSR_ S(0.077)S(0.113)S(0.81)VGSSSSYPISPAVSR S(-10.21)S(-8.57)S(8.57)VGS(-65.86)S(-73.45)S(-89.24)S(-104.52)Y(-112.58)PIS(-143.71)PAVS(-149.54)R 3 2 917.91457 -0.13705 1097600 211670 0 0 885930 0 0 0 1315 953 125 125 6138 7006 60591 36625 Mix4_TiO2_Reinj_1_1 4498 60591 36625 Mix4_TiO2_Reinj_1_1 4498 Q15149 Q15149 Q15149 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3 1 79.0047 0 0 1 79.0047 0.00311473 79.005 1 S VQGPLGSPPKRGP CDK1;CDK2;Proline-directed 0.0057 0.00311473 79.005 _TPHVQAVQGPLGpSPPK_ TPHVQAVQGPLGS(1)PPK T(-79)PHVQAVQGPLGS(79)PPK 13 3 564.95382 -0.64462 56470 0 0 0 56470 0 0 0 1316 954 20 20 6240 7129 61883 37491 Mix4_TiO2_2_1 4685 61884 37492 Mix4_TiO2_Reinj_1_1 7548 Q15149-4 Q15149-4 Q15149-4 >sp|Q15149-4|PLEC_HUMAN Isoform Plectin-11 of Plectin OS=Homo sapiens GN=PLEC 0.332428 0 0.0964396 -9.22663 0.00438645 81.132 0.332428 0 0.177168 35.662 0.138203 -7.4095 3.66289E-05 124.22 0 0 0 0 1 S LGRKRTSSEDNLY CK2;PKA 0.042 3.66289E-05 124.22 _pTSSEDNLYLAVLR_ T(0.332)S(0.332)S(0.332)EDNLY(0.003)LAVLR T(0)S(0)S(0)EDNLY(-20.88)LAVLR 2 2 780.8689 0.53286 0 0 0 0 0 0 0 0 1317 954 21 21 6240 7129 61882 37490 Mix4_TiO2_1_5 7164 61884 37492 Mix4_TiO2_Reinj_1_1 7548 Q15149-4 Q15149-4 Q15149-4 >sp|Q15149-4|PLEC_HUMAN Isoform Plectin-11 of Plectin OS=Homo sapiens GN=PLEC 0.970528 18.2848 0.970528 18.2848 0.00438645 81.132 0.332428 0 0.177168 35.662 0.787894 8.70945 3.66289E-05 124.22 0 0 0 0 1 S GRKRTSSEDNLYL CAMK2;PKA;PKA/AKT 0.001764 3.66289E-05 124.22 _TSpSEDNLYLAVLR_ T(0.014)S(0.014)S(0.971)EDNLY(0.001)LAVLR T(-18.28)S(-18.28)S(18.28)EDNLY(-31.67)LAVLR 3 2 780.8689 -0.147 818100 165290 0 0 652810 0 0 0 1318 955 65 65 6639 7601 67360 41388 Mix4_TiO2_Reinj_1_1 3446 67360 41388 Mix4_TiO2_Reinj_1_1 3446 Q15154;Q15154-2;Q15154-3 Q15154 Q15154 >sp|Q15154|PCM1_HUMAN Pericentriolar material 1 protein OS=Homo sapiens GN=PCM1 PE=1 SV=4;>sp|Q15154-2|PCM1_HUMAN Isoform 2 of Pericentriolar material 1 protein OS=Homo sapiens GN=PCM1;>sp|Q15154-3|PCM1_HUMAN Isoform 3 of Pericentriolar material 1 protein 0.980063 18.4325 0.632474 2.3599 0.021464 63.282 0 0 0.980063 18.4325 0.00238858 83.269 0 0 0 0 1 S RVTNDISPESSPG CK1;GSK3;Proline-directed 0.05 0.00238858 83.269 _VTNDIpSPESSPGVGR_ VT(0.014)NDIS(0.98)PES(0.006)SPGVGR VT(-18.43)NDIS(18.43)PES(-22.32)S(-38.62)PGVGR 6 2 797.85907 0.033789 73910 12932 0 0 60977 0 0 0 1319 957 113 113 1341 1510 12513 7628 Mix4_TiO2_Reinj_1_6 4390 12513 7628 Mix4_TiO2_Reinj_1_6 4390 Q15185 Q15185 Q15185 >sp|Q15185|TEBP_HUMAN Prostaglandin E synthase 3 OS=Homo sapiens GN=PTGES3 PE=1 SV=1 0.999994 52.0874 0 0 0.999994 52.0874 3.51087E-09 141.69 1 S KDWEDDSDEDMSN CK2 0.117 3.51087E-09 141.69 _DWEDDpSDEDM(ox)SNFDR_ DWEDDS(1)DEDMSNFDR DWEDDS(52.09)DEDMS(-52.09)NFDR 6 2 986.31476 0.24705 48281 0 0 0 48281 0 0 0 1320 958 281 281 4603;5009 5225;5226;5696;5697 43648 26766 Mix4_TiO2_1_5 7617 43647 26764 Mix4_TiO2_1_4 7830 Q15208 Q15208 Q15208 >sp|Q15208|STK38_HUMAN Serine/threonine-protein kinase 38 OS=Homo sapiens GN=STK38 PE=1 SV=1 0.874115 8.4559 0.874115 8.4559 5.07347E-19 155.89 0 0 0.491757 0 6.63808E-08 116 0 0 0.749914 5.80476 0.000309417 85.757 0.788385 6.47557 0.000448627 79.866 1 S RRQLAFSTVGTPD NEK6 0.076 5.07347E-19 155.89 _QLAFpSTVGTPDYIAPEVFM(ox)QTGYNK_ QLAFS(0.874)T(0.125)VGT(0.001)PDYIAPEVFMQTGYNK QLAFS(8.46)T(-8.46)VGT(-31.27)PDY(-32.43)IAPEVFMQT(-87.96)GY(-87.96)NK 5 3 958.44163 -0.10052 670030 114600 0 0 0 0 362400 193020 1321 960 243 243 643 739 6130 3573 Mix4_TiO2_1_3 7325 6130 3573 Mix4_TiO2_1_3 7325 Q15349-2;Q15349 Q15349-2 Q15349-2 >sp|Q15349-2|KS6A2_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens GN=RPS6KA2;>sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens GN=RPS6KA2 PE=1 SV=2 0.999411 32.5709 0.999411 32.5709 1.75954E-06 113.18 0.9601 13.815 0.000241681 95.962 1 S HDKRAYSFCGTIE CAMK2;PKA 0.003024 1.75954E-06 113.18 _AYpSFCGTIEYMAPEVVNR_ AYS(0.999)FCGT(0.001)IEYMAPEVVNR AY(-44.45)S(32.57)FCGT(-32.57)IEY(-80.7)MAPEVVNR 3 2 1093.968 0.9363 687840 107170 0 0 580670 0 0 0 1322 960 402 402 2190 2478 20091 12374 Mix4_TiO2_Reinj_1_3 8352 20091 12374 Mix4_TiO2_Reinj_1_3 8352 Q15349-2;Q15349 Q15349-2 Q15349-2 >sp|Q15349-2|KS6A2_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens GN=RPS6KA2;>sp|Q15349|KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens GN=RPS6KA2 PE=1 SV=2 0.999991 53.9022 0 0 0.999991 53.9022 0.0175974 60.343 1 S HLFRGFSFVASSL CAMK2;CHK1;CHK1/2;GSK3;PDK1;PKD 0.0001168 0.0175974 60.343 _GFpSFVASSLIQEPSQQDLHK_ GFS(1)FVASSLIQEPSQQDLHK GFS(53.9)FVAS(-53.9)S(-53.9)LIQEPS(-60.34)QQDLHK 3 3 766.69825 -1.0759 216150 0 0 0 216150 0 0 0 1323 961 173 173 4569 5189 43277 26540 Mix4_TiO2_Reinj_1_4 7508 43277 26540 Mix4_TiO2_Reinj_1_4 7508 Q15365 Q15365 Q15365 >sp|Q15365|PCBP1_HUMAN Poly(rC)-binding protein 1 OS=Homo sapiens GN=PCBP1 PE=1 SV=2 0.999992 50.7996 0.999992 50.7996 4.84184E-06 108.95 1 S LETLSQSPQGRVM CK1;NEK6;Proline-directed 0.05 4.84184E-06 108.95 _QICLVM(ox)LETLSQpSPQGR_ QICLVMLETLSQS(1)PQGR QICLVMLET(-106.13)LS(-50.8)QS(50.8)PQGR 13 3 685.99161 0.46972 88915 0 0 0 88915 0 0 0 1324 962 187 187 2532;4443 2877;5053 23795 14775 Mix4_TiO2_Reinj_1_4 6066 42247 26006 Mix4_TiO2_1_4 4433 Q15366 Q15366 Q15366 >sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 OS=Homo sapiens GN=PCBP2 PE=1 SV=1 0.586654 4.47879 0.0364745 -14.1042 0.00125571 92.575 0 0 0.586654 4.47879 0.00452405 78.471 1 S PYRPKPSSSPVIF 0.00125571 92.575 _GVTIPYRPKPpSSSPVIFAGGQDR_ GVTIPY(0.209)RPKPS(0.587)S(0.102)S(0.102)PVIFAGGQDR GVT(-41.02)IPY(-4.48)RPKPS(4.48)S(-7.6)S(-7.6)PVIFAGGQDR 11 3 837.09148 -0.66756 608500 0 0 0 608500 0 0 0 1325 962 189 189 2532;4443 2877;5053 42247 26006 Mix4_TiO2_1_4 4433 42247 26006 Mix4_TiO2_1_4 4433 Q15366 Q15366 Q15366 >sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 OS=Homo sapiens GN=PCBP2 PE=1 SV=1 0.938454 14.1042 0.938454 14.1042 0.00125571 92.575 0 0 0.709807 6.16811 0.00452405 78.471 1 S RPKPSSSPVIFAG Polo box;Proline-directed 0.00405 0.00125571 92.575 _PSSpSPVIFAGGQDR_ PS(0.036)S(0.025)S(0.938)PVIFAGGQDR PS(-14.1)S(-15.73)S(14.1)PVIFAGGQDR 4 2 749.34031 0.45059 536810 186660 0 0 350150 0 0 0 1326 963 364 364 6491 7425;7426 65534 40159 Mix4_TiO2_Reinj_1_5 7730 65535 40160 Mix4_TiO2_Reinj_1_5 7732 Q15386;Q15386-2;Q15386-3 Q15386 Q15386 >sp|Q15386|UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C PE=1 SV=3;>sp|Q15386-2|UBE3C_HUMAN Isoform 2 of Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C;>sp|Q15386-3|UBE3C_HUMAN Isoform 3 of Ubiquitin-protein ligase E3C OS=Homo sa 0.330843 0 0.152622 -4.97663 0.235934 71.671 0.330843 0 0.0069176 82.647 2 S SASCHDSASDSEE CK1;CK2;GSK3 0.081 0.0069176 82.647 _VLQTFLSQLPVSPASASCHDpSASDSEEEpSEEADKPSSPEDGR_ VLQTFLSQLPVS(0.027)PAS(0.178)AS(0.175)CHDS(0.331)AS(0.331)DS(0.33)EEES(0.624)EEADKPS(0.002)S(0.002)PEDGR VLQT(-44.01)FLS(-38.29)QLPVS(-13.45)PAS(-4.71)AS(-4.71)CHDS(0)AS(0)DS(0)EEES(4.63)EEADKPS(-25.78)S(-25.78)PEDGR 21 3 1545.9792 0.5977 0 0 0 0 0 0 0 0 1327 963 366 366 6491 7425;7426 65535 40160 Mix4_TiO2_Reinj_1_5 7732 65535 40160 Mix4_TiO2_Reinj_1_5 7732 Q15386;Q15386-2;Q15386-3 Q15386 Q15386 >sp|Q15386|UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C PE=1 SV=3;>sp|Q15386-2|UBE3C_HUMAN Isoform 2 of Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C;>sp|Q15386-3|UBE3C_HUMAN Isoform 3 of Ubiquitin-protein ligase E3C OS=Homo sa 0.51784 5.76014 0.344533 0 0.235934 71.671 0.51784 5.76014 0.0069176 82.647 2 S SCHDSASDSEEES CK2 0.117 0.0069176 82.647 _VLQTFLSQLPVSPASASCHDSApSDpSEEESEEADKPSSPEDGR_ VLQTFLSQLPVS(0.027)PAS(0.196)AS(0.196)CHDS(0.196)AS(0.518)DS(0.647)EEES(0.213)EEADKPS(0.003)S(0.003)PEDGR VLQT(-54.53)FLS(-51.52)QLPVS(-15.11)PAS(-5.76)AS(-5.76)CHDS(-5.76)AS(5.76)DS(5.33)EEES(-5.33)EEADKPS(-25.61)S(-25.61)PEDGR 23 4 1159.7362 0.96821 1553000 0 0 0 1553000 0 0 0 1328 963 368 368 6491 7425;7426 65535 40160 Mix4_TiO2_Reinj_1_5 7732 65535 40160 Mix4_TiO2_Reinj_1_5 7732 Q15386;Q15386-2;Q15386-3 Q15386 Q15386 >sp|Q15386|UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C PE=1 SV=3;>sp|Q15386-2|UBE3C_HUMAN Isoform 2 of Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C;>sp|Q15386-3|UBE3C_HUMAN Isoform 3 of Ubiquitin-protein ligase E3C OS=Homo sa 0.646528 5.32901 0.344533 0 0.235934 71.671 0.646528 5.32901 0.0069176 82.647 2 S HDSASDSEEESEE CK1;CK2;GSK3 0.081 0.0069176 82.647 _VLQTFLSQLPVSPASASCHDSApSDpSEEESEEADKPSSPEDGR_ VLQTFLSQLPVS(0.027)PAS(0.196)AS(0.196)CHDS(0.196)AS(0.518)DS(0.647)EEES(0.213)EEADKPS(0.003)S(0.003)PEDGR VLQT(-54.53)FLS(-51.52)QLPVS(-15.11)PAS(-5.76)AS(-5.76)CHDS(-5.76)AS(5.76)DS(5.33)EEES(-5.33)EEADKPS(-25.61)S(-25.61)PEDGR 25 4 1159.7362 0.96821 1553000 0 0 0 1553000 0 0 0 1329 963 372 372 6491 7425;7426 65533 40158 Mix4_TiO2_1_5 7029 65535 40160 Mix4_TiO2_Reinj_1_5 7732 Q15386;Q15386-2;Q15386-3 Q15386 Q15386 >sp|Q15386|UBE3C_HUMAN Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C PE=1 SV=3;>sp|Q15386-2|UBE3C_HUMAN Isoform 2 of Ubiquitin-protein ligase E3C OS=Homo sapiens GN=UBE3C;>sp|Q15386-3|UBE3C_HUMAN Isoform 3 of Ubiquitin-protein ligase E3C OS=Homo sa 0.630696 4.97663 0.630696 4.97663 0.235934 71.671 0.623871 4.63084 0.0069176 82.647 2 S SDSEEESEEADKP CK1 0.143 0.0069176 82.647 _VLQTFLSQLPVSPASASCHDSApSDSEEEpSEEADKPSSPEDGR_ VLQTFLSQLPVS(0.073)PAS(0.073)AS(0.153)CHDS(0.153)AS(0.345)DS(0.345)EEES(0.631)EEADKPS(0.115)S(0.115)PEDGR VLQT(-43.77)FLS(-40.35)QLPVS(-8.97)PAS(-8.97)AS(-4.98)CHDS(-4.98)AS(0)DS(0)EEES(4.98)EEADKPS(-4.98)S(-4.98)PEDGR 29 4 1159.7362 0.18746 1076600 413640 0 0 663000 0 0 0 1330 966 363 363 1234;6140 1388;1389;7008;7009 60605 36663 Mix4_TiO2_1_3 4836 60618 36713 Mix4_TiO2_Reinj_1_3 5411 Q15418 Q15418 Q15418 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.999998 56.7511 0.999998 56.7511 3.19627E-06 103.9 0 0 0.999996 53.5992 2.8559E-10 127.35 0 0 0.996286 24.4475 1.817E-06 110.03 0.986083 18.5068 4.21967E-05 98.179 1 S SRTPKDSPGIPPS CK1;Proline-directed 0.05 2.8559E-10 127.35 _TPKDpSPGIPPSAGAHQLFR_ TPKDS(1)PGIPPSAGAHQLFR T(-56.75)PKDS(56.75)PGIPPS(-78.15)AGAHQLFR 5 3 686.00524 0.33322 35345000 4875600 0 0 25501000 0 4055500 913030 1331 966 369 369 1234;6140 1388;1389;7008;7009 11571 7079 Mix4_TiO2_1_3 5235 60618 36713 Mix4_TiO2_Reinj_1_3 5411 Q15418 Q15418 Q15418 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.999981 47.1301 0.999981 47.1301 3.19627E-06 103.9 0 0 1 67.5015 2.71278E-10 127.83 0 0 1 67.2177 0.00926019 71.42 0.999943 41.6394 0.171692 41.639 1 S SPGIPPSAGAHQL 2.8559E-10 127.35 _DSPGIPPpSAGAHQLFR_ DSPGIPPS(1)AGAHQLFR DS(-47.13)PGIPPS(47.13)AGAHQLFR 8 2 865.40652 1.0125 695970 414450 0 0 281520 0 0 0 1332 966 380 380 2191 2479;2480 20110 12384 Mix4_TiO2_Reinj_1_3 7436 20094 12376 Mix4_TiO2_1_3 7388 Q15418 Q15418 Q15418 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 1 94.0892 1 93.4487 1.84047E-13 154.57 0 0 1 94.0892 1.12519E-12 143.91 0 0 0.999969 45.088 0.000655703 92.618 1 S QLFRGFSFVATGL CAMK2;CHK1;CHK1/2;PDK1;PKD 0.0001168 1.84047E-13 154.57 _GFpSFVATGLM(ox)EDDGKPR_ GFS(1)FVATGLMEDDGKPR GFS(94.09)FVAT(-94.09)GLMEDDGKPR 3 2 961.92134 0.0016403 2283600 372980 0 0 1774600 0 0 135980 1333 966 732 732 3120 3544 29702 18485 Mix4_InSol_Tio2_Reinj_1 5393 29702 18485 Mix4_InSol_Tio2_Reinj_1 5393 Q15418 Q15418 Q15418 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.994079 22.2517 0.98415 17.9329 0.0692488 62.288 0.991168 20.5212 0.136026 48.505 0.813316 6.39188 0.0693202 64.488 0.994079 22.2517 0.0386639 91.839 1 S RVRKLPSTTL___ CHK1;PKD 0.020748 0.0386639 91.839 _KLPpSTTL_ KLPS(0.994)T(0.006)TL KLPS(22.25)T(-22.25)T(-58.05)L 4 2 420.21734 -0.30776 11369000 2116800 0 0 6593300 0 1659400 999190 1334 967 604 604 5866;5867 6690;6691 57885 35183 Mix4_TiO2_Reinj_1_5 5150 57885 35183 Mix4_TiO2_Reinj_1_5 5150 Q15424 Q15424 Q15424 >sp|Q15424|SAFB1_HUMAN Scaffold attachment factor B1 OS=Homo sapiens GN=SAFB PE=1 SV=4 0.999921 41.0414 0.998677 28.7801 0.239908 28.78 0.999921 41.0414 0.046435 51.957 0.975238 15.9533 0.454891 15.953 0 0 1 S EKRSVVSFDKVKE CK1 0.081 0.046435 51.957 _SVVpSFDKVKEPR_ SVVS(1)FDKVKEPR S(-41.04)VVS(41.04)FDKVKEPR 4 3 490.91659 0.17436 142090 30445 0 0 73472 0 38178 0 1335 967 344 344 5929 6762 58430 35442 Mix4_TiO2_Reinj_1_5 7978 58429 35440 Mix4_TiO2_1_5 7309 Q15424;Q14151 Q15424 Q15424 >sp|Q15424|SAFB1_HUMAN Scaffold attachment factor B1 OS=Homo sapiens GN=SAFB PE=1 SV=4;>sp|Q14151|SAFB2_HUMAN Scaffold attachment factor B2 OS=Homo sapiens GN=SAFB2 PE=1 SV=1 0.963764 14.2547 0.923485 10.818 0.0041027 89.248 0.963764 14.2547 0.00704096 82.358 1 S APTEAPSPEARDS CK1;Proline-directed 0.05 0.0041027 89.248 _TDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPpSPEAR_ TDCEPVGLEPAVEQSSAASELAEASSEELAEAPT(0.036)EAPS(0.964)PEAR T(-61.18)DCEPVGLEPAVEQS(-49.89)S(-49.89)AAS(-50.13)ELAEAS(-49.13)S(-49.13)EELAEAPT(-14.25)EAPS(14.25)PEAR 38 3 1464.6459 0.016729 2172900 500540 0 0 1672300 0 0 0 1336 970 255 255 530 602 4954 2992 Mix4_TiO2_Reinj_1_5 7122 4954 2992 Mix4_TiO2_Reinj_1_5 7122 Q15477 Q15477 Q15477 >sp|Q15477|SKIV2_HUMAN Helicase SKI2W OS=Homo sapiens GN=SKIV2L PE=1 SV=2 0.630247 2.31599 0.602633 1.80861 0.107427 37.457 0.630247 2.31599 0.00194699 75.851 0 0 0.135182 -8.06005 0.48203 13.72 0 0 1 S APLARASSLEDLV CK2;PKA 0.042 0.00194699 75.851 _ApSSLEDLVLK_ AS(0.63)S(0.37)LEDLVLK AS(2.32)S(-2.32)LEDLVLK 2 2 577.78886 -0.19192 1463800 286270 0 0 1177600 0 0 0 1337 970 256 256 530 602 4951 2987 Mix4_InSol_TiO2_1 7611 4954 2992 Mix4_TiO2_Reinj_1_5 7122 Q15477 Q15477 Q15477 >sp|Q15477|SKIV2_HUMAN Helicase SKI2W OS=Homo sapiens GN=SKIV2L PE=1 SV=2 0.864818 8.06005 0.397367 -1.80861 0.107427 37.457 0.495967 -0.0700568 0.00194699 75.851 0 0 0.864818 8.06005 0.48203 13.72 0 0 1 S PLARASSLEDLVL CAMK2;CHK1;CHK1/2;CK2;PKD 0.003192 0.00194699 75.851 _ASpSLEDLVLK_ AS(0.135)S(0.865)LEDLVLK AS(-8.06)S(8.06)LEDLVLK 3 2 577.78886 -0.0085351 69315 0 0 0 0 0 69315 0 1338 972 444 444 5827 6645 57466 34983 Mix4_TiO2_1_5 4258 57466 34983 Mix4_TiO2_1_5 4258 Q15573;Q15573-2 Q15573 Q15573 >sp|Q15573|TAF1A_HUMAN TATA box-binding protein-associated factor RNA polymerase I subunit A OS=Homo sapiens GN=TAF1A PE=1 SV=1;>sp|Q15573-2|TAF1A_HUMAN Isoform 2 of TATA box-binding protein-associated factor RNA polymerase I subunit A OS=Homo sapiens GN=T 0.819213 6.19778 0.819213 6.19778 0.0709251 42.453 2 S RSVKKYSIVNPRL AURORA;AURORA-1;AURORA-A 0.006142092 0.0709251 42.453 _SVKKpYpSIVNPR_ S(0.247)VKKY(0.934)S(0.819)IVNPR S(-6.2)VKKY(10.58)S(6.2)IVNPR 6 2 725.84639 2.6586 88880 88880 0 0 0 0 0 0 1339 973 365 365 2487;3053 2826;3473 23421 14570 Mix4_InSol_TiO2_2 3534 23421 14570 Mix4_InSol_TiO2_2 3534 Q15629 Q15629 Q15629 >sp|Q15629|TRAM1_HUMAN Translocating chain-associated membrane protein 1 OS=Homo sapiens GN=TRAM1 PE=1 SV=3 1 73.2704 0 0 1 73.2704 3.09537E-10 126.51 0.990341 26.1294 0.830671 26.129 1 S TSNVADSPRNKKE CDK1;Proline-directed 0.0057 3.09537E-10 126.51 _GTENGVNGTLTSNVADpSPR_ GTENGVNGTLTSNVADS(1)PR GT(-126.51)ENGVNGT(-99.05)LT(-100.64)S(-73.27)NVADS(73.27)PR 17 2 984.93657 0.42303 146020 0 0 0 0 0 82060 63965 1340 974 80 80 5990 6830 59179 35955 Mix4_TiO2_1_3 5511 59180 35964 Mix4_TiO2_Reinj_1_3 6241 Q15637-6;Q15637-5;Q15637;Q15637-2;Q15637-3;Q15637-4 Q15637-6 Q15637-6 >sp|Q15637-6|SF01_HUMAN Isoform B6 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637-5|SF01_HUMAN Isoform 5 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637|SF01_HUMAN Splicing factor 1 OS=Homo sapiens GN=SF1 PE=1 SV=4;>sp|Q15637-2|SF01_HUMAN Is 0.999694 33.7326 0.999694 33.7326 0.000235233 85.61 0.99471 21.8375 3.28186E-07 102.18 2 S PNPEDRSPSPEPI Proline-directed 0.05 3.28186E-07 102.18 _TGDLGIPPNPEDRpSPpSPEPIYNSEGK_ TGDLGIPPNPEDRS(1)PS(0.539)PEPIY(0.06)NS(0.401)EGK T(-82.54)GDLGIPPNPEDRS(33.73)PS(1.29)PEPIY(-9.51)NS(-1.29)EGK 14 3 976.08964 -0.020943 6982000 938960 0 0 6043000 0 0 0 1341 974 82 82 5990 6830 59179 35955 Mix4_TiO2_1_3 5511 59180 35964 Mix4_TiO2_Reinj_1_3 6241 Q15637-6;Q15637-5;Q15637;Q15637-2;Q15637-3;Q15637-4 Q15637-6 Q15637-6 >sp|Q15637-6|SF01_HUMAN Isoform B6 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637-5|SF01_HUMAN Isoform 5 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637|SF01_HUMAN Splicing factor 1 OS=Homo sapiens GN=SF1 PE=1 SV=4;>sp|Q15637-2|SF01_HUMAN Is 0.539039 1.28659 0.539039 1.28659 0.000235233 85.61 0.277998 -1.2059 3.28186E-07 102.18 2 S PEDRSPSPEPIYN CAMK2;Proline-directed 0.042 3.28186E-07 102.18 _TGDLGIPPNPEDRpSPpSPEPIYNSEGK_ TGDLGIPPNPEDRS(1)PS(0.539)PEPIY(0.06)NS(0.401)EGK T(-82.54)GDLGIPPNPEDRS(33.73)PS(1.29)PEPIY(-9.51)NS(-1.29)EGK 16 3 976.08964 -0.020943 938960 938960 0 0 0 0 0 0 1342 974 89 89 5990 6830 59180 35964 Mix4_TiO2_Reinj_1_3 6241 59180 35964 Mix4_TiO2_Reinj_1_3 6241 Q15637-6;Q15637-5;Q15637;Q15637-2;Q15637-3;Q15637-4 Q15637-6 Q15637-6 >sp|Q15637-6|SF01_HUMAN Isoform B6 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637-5|SF01_HUMAN Isoform 5 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637|SF01_HUMAN Splicing factor 1 OS=Homo sapiens GN=SF1 PE=1 SV=4;>sp|Q15637-2|SF01_HUMAN Is 0.478268 0 0.400895 -1.28659 0.000235233 85.61 0.478268 0 3.28186E-07 102.18 2 S PEPIYNSEGKRLN 3.28186E-07 102.18 _TGDLGIPPNPEDRpSPSPEPIpYNSEGK_ TGDLGIPPNPEDRS(0.984)PS(0.059)PEPIY(0.478)NS(0.478)EGK T(-102.18)GDLGIPPNPEDRS(17.86)PS(-10.33)PEPIY(0)NS(0)EGK 23 3 976.08964 -0.16488 0 0 0 0 0 0 0 0 1343 974 463 463 6702 7674 68003 41737 Mix4_TiO2_1_3 6524 68003 41737 Mix4_TiO2_1_3 6524 Q15637-6 Q15637-6 Q15637-6 >sp|Q15637-6|SF01_HUMAN Isoform B6 of Splicing factor 1 OS=Homo sapiens GN=SF1 0.986291 18.5701 0.986291 18.5701 0.0178047 63.987 0 0 0 0 1 S CGLWGLSPASRKR Proline-directed 0.05 0.0178047 63.987 _YACGLWGLpSPASR_ YACGLWGLS(0.986)PAS(0.014)R Y(-63.99)ACGLWGLS(18.57)PAS(-18.57)R 9 2 759.33398 1.0382 34808 34808 0 0 0 0 0 0 1344 976 1049 1049 5655 6441 55202 33778 Mix4_InSol_Tio2_Reinj_1 5590 55202 33778 Mix4_InSol_Tio2_Reinj_1 5590 Q15648 Q15648 Q15648 >sp|Q15648|MED1_HUMAN Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens GN=MED1 PE=1 SV=4 0.663421 2.94702 0 0 0 0 0 0 0 0 0.663421 2.94702 0.00760267 75.555 1 S PGSAGRSQTPPGV CK1 0.143 0.00760267 75.555 _pSQTPPGVATPPIPK_ S(0.663)QT(0.337)PPGVATPPIPK S(2.95)QT(-2.95)PPGVAT(-68.63)PPIPK 1 2 735.37362 -1.6879 45258 0 0 0 0 0 0 45258 1345 977 465 465 2274 2572 20968 12849 Mix4_TiO2_1_5 3599 20968 12849 Mix4_TiO2_1_5 3599 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.999747 37.361 0.999747 37.361 0.00214363 91.632 0.999251 32.6405 0.108781 39.901 1 S TDSQSQSLRNLNI CK1 0.143 0.00214363 91.632 _GILHTDSQSQpSLR_ GILHTDSQSQS(1)LR GILHT(-77.31)DS(-37.36)QS(-41.59)QS(37.36)LR 11 2 761.35649 -0.38051 246350 120490 0 0 125860 0 0 0 1346 977 593 593 2608;6825 2968;7809;7810 69187 42401 Mix4_TiO2_Reinj_1_5 4563 69187 42401 Mix4_TiO2_Reinj_1_5 4563 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.97377 15.6949 0.78633 6.19783 0.439429 16.625 0.0662667 -11.4791 0.0247861 58.086 0.97377 15.6949 0.00244416 94.143 0 0 0.0332819 -14.6303 0.0444492 55.349 0 0 2 S HKYVSGSSPDLVT CK2 0.117 0.00244416 94.143 _YVSGpSpSPDLVTR_ YVS(0.027)GS(0.974)S(1)PDLVTR Y(-92.88)VS(-15.69)GS(15.69)S(34.29)PDLVT(-83.72)R 5 2 720.79402 0.0075657 182220 28767 0 0 153460 0 0 0 1347 977 594 594 2608;6825 2968;7809;7810 69167 42395 Mix4_TiO2_1_5 3736 69171 42399 Mix4_TiO2_Reinj_1_5 4455 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.96715 15.1145 0.96715 15.1145 0.0145041 65.096 0.931551 11.4791 0.0247861 58.086 0.875859 8.52862 0.00575739 82.253 0 0 0.966572 14.6303 0.0444492 55.349 0 0 1 S KYVSGSSPDLVTR CK1;Polo box;Proline-directed 0.00405 0.00575739 82.253 _YVSGSpSPDLVTR_ YVS(0.003)GS(0.03)S(0.967)PDLVTR Y(-65.1)VS(-25.03)GS(-15.11)S(15.11)PDLVT(-46.43)R 6 2 680.81086 0.019505 1685500 322750 44692 0 1243600 0 74385 0 1348 977 312 312 2710;2711 3087;3088 25567 15799 Mix4_InSol_TiO2_2 3005 25570 15804 Mix4_TiO2_1_5 3181 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.545288 0.938742 0.127834 -8.22422 4.36025E-07 155.16 0.100467 -9.51985 0.0662534 47.929 0.359437 0 1.03041E-05 135.36 0.545288 0.938742 4.58852E-06 140.71 0.410794 -1.56643 0.00222631 91.246 1 S KICTEQSNSPPPI 4.36025E-07 155.16 _ICTEQpSNSPPPIR_ ICT(0.015)EQS(0.545)NS(0.439)PPPIR ICT(-15.49)EQS(0.94)NS(-0.94)PPPIR 6 2 789.85273 -0.072492 11157 0 0 0 0 0 11157 0 1349 977 314 314 2710;2711 3087;3088 25566 15798 Mix4_InSol_TiO2_1 4097 25570 15804 Mix4_TiO2_1_5 3181 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.999694 35.1404 0.97853 16.5875 4.36025E-07 155.16 0.899518 9.51985 0.0662534 47.929 0.999382 34.3915 1.03041E-05 135.36 0.999694 35.1404 4.58852E-06 140.71 0.933161 14.1036 0.00222631 91.246 1 S CTEQSNSPPPIRR Proline-directed 0.05 4.36025E-07 155.16 _ICTEQSNpSPPPIR_ ICTEQSNS(1)PPPIR ICT(-99.78)EQS(-35.14)NS(35.14)PPPIR 8 2 789.85273 0.21308 1907400 238090 14355 0 624900 0 486180 543900 1350 977 578 578 4410;4434 5018;5044 41985 25882 Mix4_TiO2_Reinj_1_5 3417 42175 25978 Mix4_TiO2_Reinj_1_5 3448 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.854981 8.07582 0.0921587 -6.89463 0.986643 6.8946 0.854981 8.07582 0.016916 66.734 0 0 0 0 1 S RPRPATSTPDLAS CK2 0.117 0.016916 66.734 _PATpSTPDLASHR_ PAT(0.006)S(0.855)T(0.133)PDLAS(0.006)HR PAT(-21.55)S(8.08)T(-8.08)PDLAS(-21.63)HR 4 2 666.80082 0.16438 1007100 0 0 0 1007100 0 0 0 1351 977 620 620 5986 6826 59140 35924 Mix4_TiO2_Reinj_1_5 6252 59140 35924 Mix4_TiO2_Reinj_1_5 6252 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.99965 36.0342 0 0 0.99965 36.0342 1.02602E-07 114.85 1 S SPVVHQSLQEVSE CK2 0.117 1.02602E-07 114.85 _TFQEDSSPVVHQpSLQEVSEPLTATK_ TFQEDSSPVVHQS(1)LQEVSEPLTATK T(-78.3)FQEDS(-49.96)S(-36.03)PVVHQS(36.03)LQEVS(-40.6)EPLT(-60.28)AT(-55.47)K 13 3 946.44621 0.47547 533080 0 0 0 533080 0 0 0 1352 979 202 202 4354;4355 4952;4953 41305 25405 Mix4_TiO2_Reinj_1_2 6253 41303 25401 Mix4_TiO2_1_2 5302 Q15717 Q15717 Q15717 >sp|Q15717|ELAV1_HUMAN ELAV-like protein 1 OS=Homo sapiens GN=ELAVL1 PE=1 SV=2 1 80.6391 1 86.9332 2.27019E-11 162.54 1 80.6391 6.48631E-09 146.21 0 0 0 0 1 S LSQLYHSPARRFG CDK1;CDK2;NEK6;Proline-directed 0.0057 2.27019E-11 162.54 _NVALLSQLYHpSPAR_ NVALLSQLYHS(1)PAR NVALLS(-80.64)QLY(-90.19)HS(80.64)PAR 11 2 824.91398 0.1572 1008300 145520 0 0 862760 0 0 0 1353 980 365 365 395 451 3750 2231 Mix4_InSol_TiO2_1 6282 3750 2231 Mix4_InSol_TiO2_1 6282 Q15746;Q15746-6;Q15746-3;Q15746-2;Q15746-5;Q15746-4 Q15746 Q15746 >sp|Q15746|MYLK_HUMAN Myosin light chain kinase, smooth muscle OS=Homo sapiens GN=MYLK PE=1 SV=4;>sp|Q15746-6|MYLK_HUMAN Isoform Del-1790 of Myosin light chain kinase, smooth muscle OS=Homo sapiens GN=MYLK;>sp|Q15746-3|MYLK_HUMAN Isoform 3A of Myosin light 0.973459 15.644 0 0 0 0 0.973459 15.644 0.0740891 48.285 0 0 1 S PGLGVLSPSGEER ERK/MAPK;Proline-directed 0.0034 0.0740891 48.285 _APGLGVLpSPSGEER_ APGLGVLS(0.973)PS(0.027)GEER APGLGVLS(15.64)PS(-15.64)GEER 8 2 724.84269 0.55517 38505 0 0 0 0 0 38505 0 1354 981 1428 1428 5071 5766 49049 29965 Mix4_InSol_TiO2_1 7121 49049 29965 Mix4_InSol_TiO2_1 7121 Q15751 Q15751 Q15751 >sp|Q15751|HERC1_HUMAN Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens GN=HERC1 PE=1 SV=2 0.986098 18.5085 0.890193 9.19102 0.335808 39.737 0 0 0.986098 18.5085 3.10427E-11 120.95 0 0 1 S QQERRVSTDLPEG CAMK2;PKA 0.004788 3.10427E-11 120.95 _RVpSTDLPEGQDVYTAACNSVIHR_ RVS(0.986)T(0.014)DLPEGQDVYTAACNSVIHR RVS(18.51)T(-18.51)DLPEGQDVY(-95.92)T(-109.27)AACNS(-120.95)VIHR 3 3 890.07769 0.63422 150140 49954 0 0 0 0 100180 0 1355 982 238 238 3300 3735 31151 19300 Mix4_TiO2_1_2 2981 31151 19300 Mix4_TiO2_1_2 2981 Q15773 Q15773 Q15773 >sp|Q15773|MLF2_HUMAN Myeloid leukemia factor 2 OS=Homo sapiens GN=MLF2 PE=1 SV=1 0.994209 22.3472 0.994209 22.3472 0.00674279 79.115 0 0 0.960067 13.8097 0.0166012 61.309 0.687597 3.42618 0.111589 38.823 0.886356 8.92064 0.025939 57.76 1 S IQGPEDSPSRQSR CDK1;CDK2;Proline-directed 0.0057 0.00674279 79.115 _LAIQGPEDpSPSR_ LAIQGPEDS(0.994)PS(0.006)R LAIQGPEDS(22.35)PS(-22.35)R 9 2 675.30848 -0.054617 2011000 473320 0 0 1290800 0 125360 121530 1356 983 31 31 2724 3104 25731 15903 Mix4_TiO2_Reinj_1_4 5185 25727 15897 Mix4_TiO2_1_4 4459 Q15831 Q15831 Q15831 >sp|Q15831|STK11_HUMAN Serine/threonine-protein kinase 11 OS=Homo sapiens GN=STK11 PE=1 SV=1 0.998633 28.6362 0.98656 18.6573 3.61196E-06 156.38 0.957235 13.4993 0.00250252 123.37 0.998633 28.6362 0.00290115 120.91 0.918024 10.4917 0.00311299 79.363 0.929283 11.1863 0.00180678 93.355 1 S FIHRIDSTEVIYQ CAMK2;CHK1;PKD 0.020748 3.61196E-06 156.38 _IDpSTEVIYQPR_ IDS(0.999)T(0.001)EVIYQPR IDS(28.64)T(-28.64)EVIY(-110.4)QPR 3 2 700.82651 0.067258 4681500 851540 206830 0 3401400 0 121820 99931 1357 987;988 205;211 211 344 392 3200 1935 Mix4_TiO2_Reinj_1_5 6589 3200 1935 Mix4_TiO2_Reinj_1_5 6589 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.988024 19.1644 0 0 0.988024 19.1644 1.72487E-05 97.689 1 S PDDTQGSPDLGAV Proline-directed 0.05 1.72487E-05 97.689 _ALQAGQLENQAAPDDTQGpSPDLGAVELR_ ALQAGQLENQAAPDDT(0.012)QGS(0.988)PDLGAVELR ALQAGQLENQAAPDDT(-19.16)QGS(19.16)PDLGAVELR 19 3 982.12765 1.2878 446800 0.019656 0 0 0 446800 0 0 0 1358 987;988 572;578 578 1106;1107;5732 1244;1246;6532 10430 6419 Mix4_TiO2_1_5 6249 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.44261 4.39183 0.44261 4.39183 1.48406E-06 105.7 0 0 0.233988 0 1.29159E-06 107.32 0 0 0.147988 0 0.003505 88.81 0.0229093 -7.40136 1.41736 48.618 1 S SSRDPPSSPSSLS GSK3 0.081 1.29159E-06 107.32 _DPPpSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRK_ DPPS(0.443)S(0.161)PS(0.147)S(0.147)LS(0.056)S(0.034)PIQES(0.006)T(0.006)APELPSETQETPGPALCSPLRK DPPS(4.39)S(-4.39)PS(-4.79)S(-4.79)LS(-8.95)S(-11.11)PIQES(-18.85)T(-18.85)APELPS(-37.2)ET(-37.2)QET(-40.49)PGPALCS(-43.21)PLRK 4 3 1385.654 -0.28595 0 0 0 0 0 0 0 0 0 1359 987;988 573;579 579 1106;1107;5732 1244;1246;6532 56329 34425 Mix4_TiO2_1_5 6332 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.433434 0 0.433434 0 1.48406E-06 105.7 0 0 0.233988 0 1.29159E-06 107.32 0 0 0.147988 0 0.003505 88.81 0.070783 -2.50219 1.41736 48.618 1 S SRDPPSSPSSLSS ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 1.29159E-06 107.32 _SSRDPPpSSPSSLSSPIQESTAPELPSETQETPGPALCSPLR_ S(0.035)S(0.035)RDPPS(0.433)S(0.433)PS(0.03)S(0.03)LS(0.001)S(0.001)PIQESTAPELPSETQETPGPALCSPLR S(-10.94)S(-10.94)RDPPS(0)S(0)PS(-11.56)S(-11.56)LS(-26.33)S(-26.33)PIQES(-30.83)T(-30.83)APELPS(-36.85)ET(-40.93)QET(-44.44)PGPALCS(-53.17)PLR 8 3 1453.0108 -0.99914 0 0 0 0 0 0 0 0 0 1360 987;988 575;581 581 1106;1107;5732 1244;1246;6532 56327 34423 Mix4_TiO2_1_3 6461 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.291439 0 0.291439 0 1.48406E-06 105.7 0 0 0.233988 0 1.29159E-06 107.32 0 0 0.147988 0 0.003505 88.81 0.125936 0 1.41736 48.618 1 S DPPSSPSSLSSPI CK1;GSK3 0.081 1.29159E-06 107.32 _SSRDPPSSPpSSLSSPIQESTAPELPSETQETPGPALCSPLR_ S(0.001)S(0.001)RDPPS(0.003)S(0.013)PS(0.291)S(0.291)LS(0.291)S(0.073)PIQES(0.016)T(0.016)APELPS(0.001)ET(0.001)QETPGPALCSPLR S(-23.2)S(-22.95)RDPPS(-19.57)S(-13.35)PS(0)S(0)LS(0)S(-6)PIQES(-12.71)T(-12.71)APELPS(-26.41)ET(-26.05)QET(-30.74)PGPALCS(-54.3)PLR 10 3 1453.0108 -0.025266 0 0 0 0 0 0 0 0 0 1361 987;988 576;582 582 1106;1107;5732 1244;1246;6532 10394 6407 Mix4_TiO2_Reinj_1_5 7317 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.588085 5.91569 0.291439 0 1.48406E-06 105.7 0 0 0.588085 5.91569 1.29159E-06 107.32 0 0 0.147988 0 0.003505 88.81 0.125936 0 1.41736 48.618 1 S PPSSPSSLSSPIQ CK1 0.081 1.29159E-06 107.32 _DPPSSPSpSLSSPIQESTAPELPSETQETPGPALCSPLR_ DPPS(0.047)S(0.151)PS(0.151)S(0.588)LS(0.047)S(0.013)PIQES(0.004)T(0.001)APELPSETQETPGPALCSPLR DPPS(-11.02)S(-5.92)PS(-5.92)S(5.92)LS(-11.02)S(-16.61)PIQES(-22.01)T(-27.22)APELPS(-52.75)ET(-59.77)QET(-66.02)PGPALCS(-79.07)PLR 8 3 1342.9557 -0.02267 6840800 0.8865 0 0 0 6840800 0 0 0 1362 987;988 578;584 584 1106;1107;5732 1244;1246;6532 56327 34423 Mix4_TiO2_1_3 6461 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.291439 0 0.291439 0 1.48406E-06 105.7 0 0 0.192466 0 1.29159E-06 107.32 0 0 0.147988 0 0.003505 88.81 0.125936 0 1.41736 48.618 1 S SSPSSLSSPIQES CK1 0.081 1.29159E-06 107.32 _SSRDPPSSPpSSLSSPIQESTAPELPSETQETPGPALCSPLR_ S(0.001)S(0.001)RDPPS(0.003)S(0.013)PS(0.291)S(0.291)LS(0.291)S(0.073)PIQES(0.016)T(0.016)APELPS(0.001)ET(0.001)QETPGPALCSPLR S(-23.2)S(-22.95)RDPPS(-19.57)S(-13.35)PS(0)S(0)LS(0)S(-6)PIQES(-12.71)T(-12.71)APELPS(-26.41)ET(-26.05)QET(-30.74)PGPALCS(-54.3)PLR 13 3 1453.0108 -0.025266 0 0 0 0 0 0 0 0 0 1363 987;988 579;585 585 1106;1107;5732 1244;1246;6532 10395 6411 Mix4_TiO2_Reinj_1_5 7393 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.192466 0 0.178002 0 1.48406E-06 105.7 0 0 0.192466 0 1.29159E-06 107.32 0 0 0.147988 0 0.003505 88.81 0.125936 0 1.41736 48.618 1 S SPSSLSSPIQEST CK1;Polo box;Proline-directed 0.00405 1.29159E-06 107.32 _DPPSpSPSSLSSPIQESTAPELPSETQETPGPALCSPLR_ DPPS(0.038)S(0.192)PS(0.192)S(0.192)LS(0.192)S(0.192)PIQESTAPELPSETQETPGPALCSPLR DPPS(-7.09)S(0)PS(0)S(0)LS(0)S(0)PIQES(-34.21)T(-47.1)APELPS(-68.83)ET(-73.38)QET(-76.3)PGPALCS(-96.78)PLR 11 4 1007.4686 0.11549 0 0 0 0 0 0 0 0 0 1364 987;988 584;590 590 1106;1107;5732 1244;1246;6532 56326 34422 Mix4_InSol_Tio2_Reinj_1 7706 10395 6411 Mix4_TiO2_Reinj_1_5 7393 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.125936 0 0.0530966 -5.00196 1.48406E-06 105.7 0 0 0.00370076 -22.0115 1.29159E-06 107.32 0 0 0.00170914 -19.3745 0.003505 88.81 0.125936 0 1.41736 48.618 1 S SSPIQESTAPELP 1.29159E-06 107.32 _SSRDPPSSPpSSLSSPIQESTAPELPSETQETPGPALCSPLR_ S(0.008)S(0.008)RDPPS(0.023)S(0.071)PS(0.126)S(0.126)LS(0.126)S(0.126)PIQES(0.126)T(0.065)APELPS(0.065)ET(0.083)QET(0.045)PGPALCS(0.003)PLR S(-11.96)S(-11.96)RDPPS(-7.4)S(-2.5)PS(0)S(0)LS(0)S(0)PIQES(0)T(-2.9)APELPS(-2.9)ET(-1.8)QET(-4.46)PGPALCS(-16.23)PLR 19 4 1090.0099 0.17161 0 0 0 0 0 0 0 0 0 1365 987;988 773;779 779 1552;6251 1742;1743;7142 62066 37640 Mix4_TiO2_Reinj_1_3 8718 62071 37651 Mix4_TiO2_Reinj_1_6 7329 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.536178 1.38116 0.535515 1.23909 1.77615E-24 160.85 0.353275 0 8.6153E-08 116.42 0.536178 1.38116 3.22849E-25 173.21 0.315107 0 0.0977881 53.911 0.359739 0 9.09734E-07 100.23 0.332812 0 0.0016674 78.428 1 S GYGDRTSTFCGTP PKA 0.042 3.22849E-25 173.21 _TpSTFCGTPEFLAPEVLTDTSYTR_ T(0.39)S(0.536)T(0.064)FCGT(0.01)PEFLAPEVLTDTSYTR T(-1.38)S(1.38)T(-9.22)FCGT(-17.48)PEFLAPEVLT(-138.16)DT(-159.12)S(-162.37)Y(-162.37)T(-162.37)R 2 3 891.73118 0.27753 21807000 5748500 0 0 16058000 0 0 0 1366 987;988;989 495;501;497 497 2757 3141 26080 16126 Mix4_TiO2_Reinj_1_5 3546 26078 16123 Mix4_InSol_TiO2_1 3796 Q16512;Q16512-3;Q16512-2;Q16513 Q16512;Q16512-2;Q16513 Q16513 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 1 19.9193 0 0 1 19.9193 0.552776 19.919 1 42.148 0.139443 42.148 1 33.857 0.271004 33.857 1 S RQKKIFSKQQGKA;RQKKIFSKQQGKT 0.139443 42.148 _IFpSKQQGK_ IFS(1)KQQGK IFS(19.92)KQQGK 3 2 508.25225 0.4207 205140 0 0 0 67881 0 64678 72577 1367 987;988 533;539 539 3486 3935;3936 32886 20382 Mix4_InSol_Tio2_Reinj_2 4347 32887 20383 Mix4_TiO2_1_5 4833 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.980532 19.4378 0.861309 7.93147 5.06626E-24 164.47 0 0 0.844902 7.39252 2.74427E-18 156.27 0.410255 -0.945739 3.49282E-11 125.59 0.980532 19.4378 1.93698E-07 114.29 1 S TGTGTFSPGASPG CK1;GSK3;Proline-directed 0.05 5.06626E-24 164.47 _LIPNATGTGTFpSPGASPGSEAR_ LIPNATGTGT(0.006)FS(0.981)PGAS(0.011)PGS(0.002)EAR LIPNAT(-40.1)GT(-34.74)GT(-22.26)FS(19.44)PGAS(-19.44)PGS(-26.79)EAR 12 2 1084.5046 -0.1518 1299000 3.3329 393750 0 0 879390 0 0 25883 1368 987;988 537;543 543 3486 3935;3936 32897 20388 Mix4_TiO2_1_5 5029 32897 20388 Mix4_TiO2_1_5 5029 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.977337 16.5501 0.977337 16.5501 3.90247E-11 124.2 0 0 0.940923 12.8217 0.00632134 73.083 0.510068 0.945739 3.49282E-11 125.59 0.0111604 -19.4378 1.93698E-07 114.29 2 S TFSPGASPGSEAR CK1;Proline-directed 0.05 3.90247E-11 124.2 _LIPNATGTGTFpSPGApSPGSEAR_ LIPNATGTGT(0.142)FS(0.858)PGAS(0.977)PGS(0.023)EAR LIPNAT(-56.21)GT(-44.43)GT(-7.86)FS(7.86)PGAS(16.55)PGS(-16.55)EAR 16 2 1124.4878 0.67964 1100700 2.8241 183480 0 0 917220 0 0 0 1369 987;988 559;565 565 3606;6256 4064;4066;7147 33907 20882 Mix4_TiO2_1_5 3283 33908 20883 Mix4_TiO2_Reinj_1_5 4009 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.981543 15.3459 0.981543 15.3459 0.00800582 75.628 0.0535165 -11.9216 0.0013348 95.419 0.981008 17.1146 0.000741667 98.196 0.194049 -5.33549 0.0474388 53.041 0.187052 0 9.3699E-07 99.648 0.0674364 -10.2625 7.27936E-07 103.77 2 S LNLGTDSDSSPQK 0.000741667 98.196 _LNLGTDpSDpSSPQK_ LNLGTDS(0.982)DS(0.65)S(0.368)PQK LNLGT(-57.65)DS(15.35)DS(2.57)S(-2.57)PQK 7 2 761.29713 0.07295 304830 0.82665 76753 0 0 228080 0 0 0 1370 987;988 561;567 567 3606;6256 4064;4066;7147 33907 20882 Mix4_TiO2_1_5 3283 33908 20883 Mix4_TiO2_Reinj_1_5 4009 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.650434 2.57174 0.650434 2.57174 0.00800582 75.628 0.112526 -8.69391 0.0013348 95.419 0.114295 -8.83532 4.3179E-09 166.79 0.141407 -6.70989 0.0474388 53.041 0.187052 0 9.3699E-07 99.648 0.148752 -6.82677 7.27936E-07 103.77 2 S LGTDSDSSPQKSS CK1 0.143 0.000741667 98.196 _LNLGTDpSDpSSPQK_ LNLGTDS(0.982)DS(0.65)S(0.368)PQK LNLGT(-57.65)DS(15.35)DS(2.57)S(-2.57)PQK 9 2 761.29713 0.07295 76753 0.20814 76753 0 0 0 0 0 0 1371 987;988 562;568 568 3606;6256 4064;4066;7147 33877 20862 Mix4_TiO2_1_4 3259 33878 20864 Mix4_TiO2_1_5 3186 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.999963 44.3015 0.999963 44.3015 3.10761E-13 176.29 0.888356 9.00878 0.0013348 95.419 0.999952 43.4761 4.3179E-09 166.79 0.831974 10.8103 0.0474388 53.041 0.950965 12.8952 9.3699E-07 99.648 0.948669 12.6768 7.27936E-07 103.77 1 S GTDSDSSPQKSSR CDK1;CDK2;CK1;GSK3;Polo box;Proline-directed 0.00405 3.10761E-13 176.29 _LNLGTDSDSpSPQK_ LNLGTDSDSS(1)PQK LNLGT(-115.67)DS(-67.85)DS(-44.3)S(44.3)PQK 10 2 721.31396 0.080857 19399000 52.607 4581800 81804 0 13429000 29638 783580 493210 1372 987;988 112;118 118 4931 5607 47427 28962 Mix4_TiO2_Reinj_1_6 6814 47427 28962 Mix4_TiO2_Reinj_1_6 6814 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.559828 4.12319 0.559828 4.12319 4.02231E-10 119.03 0.331903 0.302142 0.00572419 90.06 1 S THDGPQSPGAGGP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.02231E-10 119.03 _RLDLLHQQLQELHAHVVLPDPAATHDGPQpSPGAGGPTCSATNLSR_ RLDLLHQQLQELHAHVVLPDPAAT(0.005)HDGPQS(0.56)PGAGGPT(0.128)CS(0.217)AT(0.068)NLS(0.022)R RLDLLHQQLQELHAHVVLPDPAAT(-20.27)HDGPQS(4.12)PGAGGPT(-6.42)CS(-4.12)AT(-9.12)NLS(-14.02)R 30 4 1211.3437 -0.43343 623660 0 0 0 623660 0 0 0 1373 987;988 69;75 75 5437 6188 53043 32422 Mix4_TiO2_Reinj_1_5 8832 53043 32422 Mix4_TiO2_Reinj_1_5 8832 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 1 63.7376 1 60.2182 0.00706084 60.218 1 63.7376 0.00588286 63.738 1 S TTDLGRSLGPVEL NEK6 0.076 0.00588286 63.738 _pSLGPVELLLR_ S(1)LGPVELLLR S(63.74)LGPVELLLR 1 2 588.82304 -0.20895 84247 15921 0 0 68326 0 0 0 1374 987;988 916;922 922 5951;5952 6788;6789 58750 35662 Mix4_TiO2_Reinj_1_1 6860 58801 35700 Mix4_TiO2_1_5 6248 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.999997 56.002 0.999997 55.3943 5.6501E-63 243.38 0.999984 47.9394 1.05333E-32 190.16 0.999997 56.002 5.95251E-39 206.92 0.999277 31.4061 1.1472E-16 146.74 0.938872 11.8637 8.89738E-18 145.78 0.991722 20.8042 0.0667466 57.384 1 S GEAPTLSPPRDAR CDK1;CDK2;Proline-directed 0.0057 5.6501E-63 243.38 _TDVSNFDEEFTGEAPTLpSPPR_ TDVSNFDEEFTGEAPTLS(1)PPR T(-202.46)DVS(-202.46)NFDEEFT(-162.26)GEAPT(-56)LS(56)PPR 18 2 1195.0152 0.11149 86146000 22874000 715350 0 61462000 112880 505050 477060 1375 989 535 535 279 319 2631 1647 Mix4_TiO2_1_5 6337 2631 1647 Mix4_TiO2_1_5 6337 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.863513 10.9317 0.863513 10.9317 2.18381E-12 132.32 0.624142 3.17598 0.00907723 73.372 0.65896 5.41991 3.95704E-05 96.116 0.042119 -8.79711 0.0235501 63.225 0.0384557 -11.3735 0.0167541 68.014 1 S NHSGTFSPQAPVP CK1;Proline-directed 0.05 2.18381E-12 132.32 _AIPTVNHSGTFpSPQAPVPTTVPVVDVR_ AIPT(0.07)VNHS(0.033)GT(0.033)FS(0.864)PQAPVPTTVPVVDVR AIPT(-10.93)VNHS(-14.12)GT(-14.12)FS(10.93)PQAPVPT(-112.29)T(-116.71)VPVVDVR 12 3 956.15481 0.48028 2537200 678940 128230 0 1730000 0 0 0 1376 989 582 582 531 603 4964 2996 Mix4_InSol_Tio2_Reinj_1 5911 4967 3001 Mix4_TiO2_1_3 4899 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.921392 10.6898 0.69646 3.6068 5.41187E-07 131.8 0.5 0 0.0228037 61.158 0.88461 8.84582 1.6284E-06 120.36 0 0 0.909351 10.0137 0.000119238 107.92 0.921392 10.6898 1.73768E-06 119.21 1 S PAPPRASSLGEID PKA 0.042 5.41187E-07 131.8 _ApSSLGEIDESSELR_ AS(0.921)S(0.079)LGEIDESSELR AS(10.69)S(-10.69)LGEIDES(-119.21)S(-119.21)ELR 2 2 786.84308 -0.039114 22627000 332.24 4072300 91691 0 13292000 0 2866600 2304200 1377 989 583 583 531 603 4966 2999 Mix4_TiO2_1_1 4440 4967 3001 Mix4_TiO2_1_3 4899 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.861452 7.93631 0.861452 7.93631 5.41187E-07 131.8 0.5 0 0.0228037 61.158 0.861362 7.93307 1.6284E-06 120.36 0 0 0.34743 0 0.000119238 107.92 0.499997 0 1.73768E-06 119.21 1 S APPRASSLGEIDE CAMK2;CK2 0.042 5.41187E-07 131.8 _ASpSLGEIDESSELR_ AS(0.139)S(0.861)LGEIDESSELR AS(-7.94)S(7.94)LGEIDES(-89.87)S(-89.87)ELR 3 2 786.84308 0.25031 1328700 19.511 258910 91691 0 806440 0 0 171670 1378 989 360 360 588;589;5384 675;676;677;6127 5593 3325 Mix4_TiO2_2_2 5625 5594 3326 Mix4_TiO2_Reinj_1_5 6730 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.909733 10.1108 0.0136859 -13.1002 0.0155781 61.906 0.909733 10.1108 0.0294092 59.454 0.872517 8.37649 0.000691393 94.776 0.860658 8.50112 0.000450729 85.344 0.00109669 -25.9875 0.603599 35.383 1 S VALPGWSPSETRS CK2;Proline-directed 0.05 0.000691393 94.776 _ATSVALPGWpSPSETR_ ATSVALPGWS(0.91)PS(0.089)ET(0.002)R AT(-59.45)S(-59.45)VALPGWS(10.11)PS(-10.11)ET(-27.59)R 10 2 819.8798 1.2426 641100 0 24316 0 571790 0 44991 0 1379 989 362 362 588;589;5384 675;676;677;6127 52328 32011 Mix4_InSol_TiO2_1 7445 5594 3326 Mix4_TiO2_Reinj_1_5 6730 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.561612 7.15096 0.102815 -4.34234 0.0155781 61.906 0.0886813 -10.1108 0.0294092 59.454 0.19885 0 0.000691393 94.776 0.561612 7.15096 0.000450729 85.344 0.0182756 -13.7696 0.603599 35.383 1 S LPGWSPSETRSSF GSK3 0.081 0.000691393 94.776 _SKATSVALPGWSPpSETRSSFMSR_ SKATSVALPGWS(0.108)PS(0.562)ET(0.108)RS(0.108)S(0.108)FMS(0.005)R S(-85.34)KAT(-85.34)S(-83.24)VALPGWS(-7.15)PS(7.15)ET(-7.15)RS(-7.15)S(-7.15)FMS(-20.11)R 14 3 850.39999 -0.41121 137990 0 0 0 0 0 137990 0 1380 989 367 367 589;5384 676;677;6127 52329 32012 Mix4_InSol_Tio2_Reinj_1 7415 52328 32011 Mix4_InSol_TiO2_1 7445 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.43534 0.570513 0.296358 0 0.0155781 61.906 0.278491 0 0.0485722 57.131 0.108228 -7.15096 0.000450729 85.344 0.43534 0.570513 0.603599 35.383 1 S PSETRSSFMSRTS AURORA;PKA 0.038874 0.000450729 85.344 _SKATSVALPGWSPSETRSpSFMSR_ SKATSVALPGWS(0.001)PS(0.018)ET(0.077)RS(0.382)S(0.435)FMS(0.087)R S(-35.38)KAT(-35.38)S(-35.38)VALPGWS(-25.99)PS(-13.77)ET(-7.54)RS(-0.57)S(0.57)FMS(-7.02)R 19 3 850.39999 -0.47844 0 0 0 0 0 0 0 0 1381 989 370 370 589;5384 676;677;6127 5601 3327 Mix4_TiO2_1_5 5850 52328 32011 Mix4_InSol_TiO2_1 7445 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.296358 0 0.296358 0 0.0155781 61.906 0.19885 0 0.0485722 57.131 0.0054754 -20.1102 0.000450729 85.344 0.0865089 -7.01768 0.603599 35.383 1 S TRSSFMSRTSKSK CK1 0.081 0.000450729 85.344 _ATSVALPGWSPSETRpSSFM(ox)SR_ ATSVALPGWS(0.002)PS(0.055)ET(0.055)RS(0.296)S(0.296)FMS(0.296)R AT(-61.91)S(-61.91)VALPGWS(-22.53)PS(-7.34)ET(-7.34)RS(0)S(0)FMS(0)R 20 3 784.02263 -0.00833 0 0 0 0 0 0 0 0 1382 989 952 952 1464;2404;2405 1646;2725;2726 22451 14029 Mix4_TiO2_Reinj_1_5 7091 13692 8365 Mix4_TiO2_2_2 6376 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.37834 0 0.106131 -8.87453 6.89928E-35 191.07 0.000353932 -34.5088 3.89764E-45 207.33 0.37834 0 3.48587E-18 152.4 0.019565 -16.8225 1.89448 16.823 0.00657181 -21.763 6.12632E-05 95.401 0.0114429 -19.3123 0.699488 38.207 1 S FDDEFTSEAPILT 3.89764E-45 207.33 _GREDVSNFDDEFpTSEAPILTPPREPR_ GREDVS(0.205)NFDDEFT(0.378)S(0.378)EAPILT(0.038)PPREPR GREDVS(-2.66)NFDDEFT(0)S(0)EAPILT(-9.96)PPREPR 14 2 1527.6957 0.85911 0 0 0 0 0 0 0 0 1383 989 302 302 2797 3187 26810 16771 Mix4_TiO2_Reinj_1_5 8333 26810 16771 Mix4_TiO2_Reinj_1_5 8333 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.998964 29.8495 0.758303 6.34211 0.442484 32.691 0.998964 29.8495 5.12606E-11 136.29 1 S LSLVAASPTLSPR GSK3;Proline-directed 0.05 5.12606E-11 136.29 _IIIEELSLVAApSPTLSPR_ IIIEELSLVAAS(0.999)PT(0.001)LSPR IIIEELS(-111.66)LVAAS(29.85)PT(-29.85)LS(-56.44)PR 12 3 663.69378 -0.12907 480580 20747 0 0 459830 0 0 0 1384 989 306 306 2797 3187 26811 16774 Mix4_TiO2_Reinj_1_5 8530 26810 16771 Mix4_TiO2_Reinj_1_5 8333 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.990473 20.1693 0.909879 10.089 0.442484 32.691 0.990473 20.1693 5.12606E-11 136.29 1 S AASPTLSPRQSMI CDK1;CK1;GSK3;Proline-directed 0.0057 5.12606E-11 136.29 _IIIEELSLVAASPTLpSPR_ IIIEELSLVAASPT(0.01)LS(0.99)PR IIIEELS(-121.61)LVAAS(-60.16)PT(-20.17)LS(20.17)PR 16 3 663.69378 -0.33023 314320 21258 0 0 293060 0 0 0 1385 989 110 110 3654 4120 34360 21330 Mix4_TiO2_Reinj_1_5 6646 34360 21330 Mix4_TiO2_Reinj_1_5 6646 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.999999 62.4721 0 0 0.999999 62.4721 6.54106E-07 105.19 1 S NAHIVVSDPEDIT CK2 0.117 6.54106E-07 105.19 _LQELNAHIVVpSDPEDITDCPR_ LQELNAHIVVS(1)DPEDITDCPR LQELNAHIVVS(62.47)DPEDIT(-62.47)DCPR 11 3 834.38412 0.42858 893670 0 0 0 893670 0 0 0 1386 989 815 815 6252 7143 62113 37668 Mix4_TiO2_1_3 8079 62128 37694 Mix4_TiO2_Reinj_1_5 8566 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.515225 1.05976 0.515225 1.05976 3.54726E-12 135.51 0.344575 0 8.02328E-07 102.34 0.358442 0 2.30988E-17 146.73 0 0 0.317036 0 0.000509078 83.595 0.321195 0 0.216594 44.418 1 S GYGDRTSTFCGTP PKA 0.042 2.30988E-17 146.73 _TpSTFCGTPEFLAPEVLTETSYTR_ T(0.404)S(0.515)T(0.079)FCGT(0.002)PEFLAPEVLTETSYTR T(-1.06)S(1.06)T(-8.15)FCGT(-23.74)PEFLAPEVLT(-103.75)ET(-108.58)S(-108.58)Y(-108.58)T(-108.58)R 2 3 896.40306 -0.09795 1142700 1142700 0 0 0 0 0 0 1387 992 740 740 2249 2545 20775 12735 Mix4_InSol_Tio2_Reinj_1 3044 20782 12757 Mix4_TiO2_Reinj_1_5 2898 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.999997 55.1859 0.999988 49.1502 0.000931052 102.87 0.974281 16.2992 0.24137 28.311 0.999988 49.3391 0.000586111 109.4 0 0 0.999916 40.867 0.00808715 76.687 0.999997 55.1859 0.00518892 84.293 1 S PRGGTVSPPPGTS Proline-directed 0.05 0.000586111 109.4 _GGTVpSPPPGTSR_ GGTVS(1)PPPGTSR GGT(-55.19)VS(55.19)PPPGT(-73.42)S(-79.01)R 5 2 596.77153 -0.2506 5294800 989770 27901 0 3659600 0 325420 292110 1388 992 789 789 2722;4441 3101;3102;5051 25713 15885 Mix4_TiO2_1_3 7818 25713 15885 Mix4_TiO2_1_3 7818 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 1 63.9509 1 63.9509 1.33228E-25 167.3 4.38626E-09 -83.5791 0.00538796 83.579 0.999999 62.6283 6.33169E-07 103.35 2 S SAGPRPSPLPSPQ GSK3;PKA;Proline-directed 0.042 1.33228E-25 167.3 _IDPWSFVSAGPRPpSPLPpSPQPAPR_ IDPWSFVSAGPRPS(1)PLPS(1)PQPAPR IDPWS(-127.28)FVS(-63.95)AGPRPS(63.95)PLPS(78.94)PQPAPR 14 3 906.09433 -0.20796 1285700 276880 0 0 1008800 0 0 0 1389 992 793 793 2722;4441 3101;3102;5051 42242 26003 Mix4_TiO2_2_3 3426 25708 15882 Mix4_TiO2_Reinj_1_3 8288 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 1 83.5791 1 69.2918 1.07595E-17 143.48 1 83.5791 0.00538796 83.579 1 73.1063 2.03647E-25 162.72 1 S RPSPLPSPQPAPR CK1;Proline-directed 0.05 2.03647E-25 162.72 _PSPLPpSPQPAPR_ PSPLPS(1)PQPAPR PS(-83.58)PLPS(83.58)PQPAPR 6 2 662.32648 0.11397 1679700 375590 46991 0 1257100 0 0 0 1390 992 507 507 2929;2930 3333;3334 27975 17406 Mix4_TiO2_Reinj_1_5 4532 27968 17397 Mix4_TiO2_1_3 3784 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 1 96.595 1 114.576 0.000299092 136.99 1 74.4265 0.00511931 74.427 1 96.595 0.00151566 96.595 0 0 1 108.065 0.00229826 108.07 1 127.526 0.00107146 132.22 1 S RITVQASPGLDRR CK1;Proline-directed 0.05 0.000299092 136.99 _ITVQApSPGLDR_ ITVQAS(1)PGLDR IT(-96.59)VQAS(96.59)PGLDR 6 2 618.80283 0.1307 8313200 1824800 185770 0 4321800 0 1109600 871300 1391 992 524 524 4364;4972 4963;5654 41396 25449 Mix4_InSol_TiO2_1 7628 41400 25456 Mix4_TiO2_1_3 6329 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.997315 25.6994 0.991695 20.7705 4.7206E-22 196.53 0 0 0.972504 15.4862 9.69685E-12 160.78 0 0 0.997315 25.6994 9.69685E-12 160.78 0.613603 2.00854 3.25025E-09 142.78 1 S EVGPGDSPTFPRF Proline-directed 0.05 4.7206E-22 196.53 _NVFEVGPGDpSPTFPR_ NVFEVGPGDS(0.997)PT(0.003)FPR NVFEVGPGDS(25.7)PT(-25.7)FPR 10 2 849.8798 0.37392 9596100 2607000 0 0 5474700 0 822890 691490 1392 992 770 770 4435 5045 42183 25980 Mix4_TiO2_Reinj_1_5 2806 42182 25979 Mix4_TiO2_Reinj_1_3 2652 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 1 7.78195 0 0 0 0 1 7.78195 0.102386 54.408 0 0 0 0 1 S ISRPRPSPLRSRI CDK1;CDK2;GSK3;PKA;Proline-directed 0.0057 0.102386 54.408 _PRPpSPLR_ PRPS(1)PLR PRPS(7.78)PLR 4 2 451.73403 -0.11209 1106800 0 0 0 1106800 0 0 0 1393 992 748 748 5108 5811 49371 30120 Mix4_TiO2_1_3 1835 49371 30120 Mix4_TiO2_1_3 1835 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.999958 45.5672 0.999958 45.5672 0.0425924 48.454 0.999932 44.6851 0.0539749 44.685 0.407621 1.38688 0.758889 1.3869 0 0 1 S PPGTSRSAPGTPG 0.0425924 48.454 _pSAPGTPGTPR_ S(1)APGTPGTPR S(45.57)APGT(-45.57)PGT(-48.45)PR 1 2 510.72914 0.67511 597830 138580 0 0 459250 0 0 0 1394 992 35 35 5569 6346 54492 33360 Mix4_InSol_Tio2_Reinj_1 5050 54491 33359 Mix4_InSol_TiO2_1 5108 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.99938 32.7747 0 0 0.695093 4.24603 0.437776 46.806 0.99875 29.7271 0.00022215 83.394 0.99938 32.7747 0.0115038 71.671 1 S GGRPEGSPKAAGY CDK1;Proline-directed 0.0057 0.00022215 83.394 _SPLGSWNGSGSGGGGGGGGGRPEGpSPK_ SPLGSWNGSGS(0.001)GGGGGGGGGRPEGS(0.999)PK S(-71.67)PLGS(-71.67)WNGS(-40.36)GS(-32.77)GGGGGGGGGRPEGS(32.77)PK 25 3 798.34705 -0.19059 725240 0 0 0 163610 0 329950 231670 1395 992 758 758 5571 6348 54502 33370 Mix4_TiO2_Reinj_1_3 6127 54500 33364 Mix4_TiO2_1_3 5231 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 1 91.0897 1 96.0007 0.00208541 96.001 1 91.0897 0.00166079 91.09 1 S TPGTPRSPPLGLI ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00208541 96.001 _pSPPLGLISR_ S(1)PPLGLISR S(91.09)PPLGLIS(-91.09)R 1 2 510.2679 -0.057898 838350 218310 0 0 620040 0 0 0 1396 992 705 705 6132 6999;7000 60541 36598 Mix4_TiO2_1_3 8752 60541 36598 Mix4_TiO2_1_3 8752 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.926429 11.0011 0.926429 11.0011 2.07485E-32 177.38 0.916677 10.4252 4.12675E-11 123.44 0.921585 10.7035 4.2313E-17 150.48 0 0 1 S SLKTPDSPPTPAP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.07485E-32 177.38 _TPDpSPPTPAPLLLDLGIPVGQR_ T(0.074)PDS(0.926)PPTPAPLLLDLGIPVGQR T(-11)PDS(11)PPT(-58.43)PAPLLLDLGIPVGQR 4 2 1167.6089 0.022991 19648000 10154000 408960 0 9085000 0 0 0 1397 994 28 28 2492;4902 2831;2832;5574 23442 14582 Mix4_TiO2_Reinj_1_4 7827 23441 14581 Mix4_TiO2_Reinj_1_2 6837 Q16637;Q16637-3;Q16637-2;Q16637-4 Q16637 Q16637 >sp|Q16637|SMN_HUMAN Survival motor neuron protein OS=Homo sapiens GN=SMN1 PE=1 SV=1;>sp|Q16637-3|SMN_HUMAN Isoform Iso7-SMN of Survival motor neuron protein OS=Homo sapiens GN=SMN1;>sp|Q16637-2|SMN_HUMAN Isoform Iso5-SMN of Survival motor neuron protein O 0.974758 15.8748 0.997707 26.3856 1.2827E-47 236.85 0.974758 15.8748 1.00191E-47 240.38 0 0 1 S RRGTGQSDDSDIW 1.00191E-47 240.38 _GTGQpSDDSDIWDDTALIK_ GT(0.025)GQS(0.975)DDSDIWDDTALIK GT(-15.87)GQS(15.87)DDS(-43.72)DIWDDT(-160.82)ALIK 5 2 1008.9253 0.2927 1214100 234560 0 0 979510 0 0 0 1398 994 31 31 2492;4902 2831;2832;5574 23447 14585 Mix4_TiO2_1_4 7449 23447 14585 Mix4_TiO2_1_4 7449 Q16637;Q16637-3;Q16637-2;Q16637-4 Q16637 Q16637 >sp|Q16637|SMN_HUMAN Survival motor neuron protein OS=Homo sapiens GN=SMN1 PE=1 SV=1;>sp|Q16637-3|SMN_HUMAN Isoform Iso7-SMN of Survival motor neuron protein OS=Homo sapiens GN=SMN1;>sp|Q16637-2|SMN_HUMAN Isoform Iso5-SMN of Survival motor neuron protein O 0.999997 55.7541 0.999997 55.7541 1.2827E-47 236.85 0.999929 41.492 1.09419E-38 222.57 0 0 2 S TGQSDDSDIWDDT CK1 0.081 1.2827E-47 236.85 _GTGQpSDDpSDIWDDTALIK_ GT(0.002)GQS(0.998)DDS(1)DIWDDTALIK GT(-26.39)GQS(26.39)DDS(55.75)DIWDDT(-128.28)ALIK 8 2 1048.9085 -0.060331 510450 267380 0 0 243080 0 0 0 1399 994 63 63 4038 4600 38175 23435 Mix4_InSol_Tio2_Reinj_1 2744 38174 23434 Mix4_InSol_TiO2_1 2718 Q16637;Q16637-3;Q16637-2;Q16637-4 Q16637 Q16637 >sp|Q16637|SMN_HUMAN Survival motor neuron protein OS=Homo sapiens GN=SMN1 PE=1 SV=1;>sp|Q16637-3|SMN_HUMAN Isoform Iso7-SMN of Survival motor neuron protein OS=Homo sapiens GN=SMN1;>sp|Q16637-2|SMN_HUMAN Isoform Iso5-SMN of Survival motor neuron protein O 0.386646 0 0.0047654 -23.0387 0.10798 47.537 0.386646 0 0.956313 14.351 1 S GDICETSGKPKTT 0.10798 47.537 _NGDICEpTSGKPKTTPK_ NGDICET(0.387)S(0.387)GKPKT(0.113)T(0.113)PK NGDICET(0)S(0)GKPKT(-5.33)T(-5.33)PK 8 3 604.94477 0.57083 0 0 0 0 0 0 0 0 1400 995 144 144 3740 4219 35333 21861 Mix4_TiO2_Reinj_1_5 3539 35331 21859 Mix4_TiO2_1_5 2852 Q16643-2;Q16643 Q16643-2 Q16643-2 >sp|Q16643-2|DREB_HUMAN Isoform 2 of Drebrin OS=Homo sapiens GN=DBN1;>sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens GN=DBN1 PE=1 SV=4 0.998941 29.7464 0.998726 28.9444 0.111733 46.409 0 0 0.998941 29.7464 0.11963 45.195 0.989255 19.641 0.529604 20.506 0.985853 18.4316 0.264193 34.247 1 S GLARLSSPVLHRL CAMK2;CHK1;CHK1/2;PKD;Polo box;Proline-directed 0.003192 0.111733 46.409 _LSpSPVLHR_ LS(0.001)S(0.999)PVLHR LS(-29.75)S(29.75)PVLHR 3 2 494.75242 0.32263 584510 55615 0 0 394710 0 75000 59181 1401 996 386 386 351 399;400 3292 1979 Mix4_TiO2_Reinj_1_5 5930 3292 1979 Mix4_TiO2_Reinj_1_5 5930 Q16659 Q16659 Q16659 >sp|Q16659|MK06_HUMAN Mitogen-activated protein kinase 6 OS=Homo sapiens GN=MAPK6 PE=1 SV=1 1 82.0392 1 65.1989 1.00663E-16 174.22 1 82.0392 3.66356E-20 187.64 1 S LDPRALSDVTDEE CAMK2 0.042 3.66356E-20 187.64 _ALpSDVTDEEEVQVDPR_ ALS(1)DVTDEEEVQVDPR ALS(82.04)DVT(-82.04)DEEEVQVDPR 3 2 941.40932 0.61958 186890 54236 0 0 132660 0 0 0 1402 996 665 665 2253 2549 20810 12772 Mix4_TiO2_Reinj_1_5 7767 20808 12770 Mix4_TiO2_Reinj_1_3 7887 Q16659 Q16659 Q16659 >sp|Q16659|MK06_HUMAN Mitogen-activated protein kinase 6 OS=Homo sapiens GN=MAPK6 PE=1 SV=1 1 117.97 1 112.104 3.1755E-06 112.1 1 117.97 9.18403E-13 146.25 1 0.967975 1.43608 0.96797 0 0 1 S EGFLNNSGEFLFN NEK6 0.076 9.18403E-13 146.25 _GHEEGFLNNpSGEFLFNK_ GHEEGFLNNS(1)GEFLFNK GHEEGFLNNS(117.97)GEFLFNK 10 2 1009.9358 0.87387 1007100 49424 0 0 912240 0 45440 0 1403 996 189 189 2256 2552 20831 12782 Mix4_TiO2_1_5 3554 20826 12776 Mix4_InSol_TiO2_1 4611 Q16659 Q16659 Q16659 >sp|Q16659|MK06_HUMAN Mitogen-activated protein kinase 6 OS=Homo sapiens GN=MAPK6 PE=1 SV=1 0.999999 62.0719 0.999999 62.0719 0.00641522 62.072 0.999999 59.5718 0.00690585 60.559 0.999998 57.0897 0.00507162 66.215 0.999996 53.8239 0.0246485 54.395 1 S SHKGHLSEGLVTK 0.00507162 66.215 _GHLpSEGLVTK_ GHLS(1)EGLVTK GHLS(62.07)EGLVT(-62.07)K 4 2 560.77355 -0.21359 3317500 625780 0 0 1943700 0 403660 344350 1404 996 451 451 5760 6563 56641 34565 Mix4_TiO2_Reinj_1_3 8298 56641 34565 Mix4_TiO2_Reinj_1_3 8298 Q16659 Q16659 Q16659 >sp|Q16659|MK06_HUMAN Mitogen-activated protein kinase 6 OS=Homo sapiens GN=MAPK6 PE=1 SV=1 0.653305 2.75168 0.645314 2.59969 0.00159848 128.96 0.653305 2.75168 0.000193615 140.93 1 S NYKTRSSSYLDNL PKA 0.042 0.000193615 140.93 _SpSSYLDNLVWR_ S(0.347)S(0.653)SYLDNLVWR S(-2.75)S(2.75)S(-65.2)Y(-125.35)LDNLVWR 2 2 710.31885 0.096152 625700 163040 0 0 462660 0 0 0 1405 997 637 637 4967 5648 47926 29300 Mix4_TiO2_Reinj_1_5 6777 47926 29300 Mix4_TiO2_Reinj_1_5 6777 Q16825 Q16825 Q16825 >sp|Q16825|PTN21_HUMAN Tyrosine-protein phosphatase non-receptor type 21 OS=Homo sapiens GN=PTPN21 PE=1 SV=2 1 93.8453 1 93.8453 4.87819E-06 108.88 1 S QLHKRNSIEVAGL AURORA;AURORA-1;AURORA-A;CHK1;PKA;PKD 0.006142092 4.87819E-06 108.88 _RNpSIEVAGLSHGLEGLR_ RNS(1)IEVAGLSHGLEGLR RNS(93.85)IEVAGLS(-93.85)HGLEGLR 3 3 629.98607 -0.44068 98414 0 0 0 98414 0 0 0 1406 999;1000 34;34 34 5082 5779 49163 30020 Mix4_TiO2_1_3 2591 49163 30020 Mix4_TiO2_1_3 2591 Q16891;Q16891-3;Q16891-2 Q16891;Q16891-2 Q16891 >sp|Q16891|IMMT_HUMAN Mitochondrial inner membrane protein OS=Homo sapiens GN=IMMT PE=1 SV=1;>sp|Q16891-3|IMMT_HUMAN Isoform 3 of Mitochondrial inner membrane protein OS=Homo sapiens GN=IMMT;>sp|Q16891-2|IMMT_HUMAN Isoform 2 of Mitochondrial inner membrane 0.975013 16.808 0.975013 16.808 0.0323083 58.209 0 0 0.657604 5.21019 0.0708163 49.087 0.89782 10.3434 0.18981 36.702 0.227055 3.13081 1.11321 3.1308 1 S RPCRRYSTSGSSG CAMK2;GSK3;PKA;PKA/AKT 0.00111111 0.0323083 58.209 _RYpSTSGSSGLTTGK_ RYS(0.975)T(0.02)S(0.004)GSSGLTTGK RY(-41.04)S(16.81)T(-16.81)S(-24.31)GS(-33.06)S(-33.06)GLT(-58.21)T(-58.21)GK 3 2 741.33523 0.94719 426860 77305 0 0 276170 0 73391 0 1407 1001 97 97 4695 5333 44646 27383 Mix4_TiO2_Reinj_1_3 5843 44644 27379 Mix4_TiO2_1_3 5062 Q17RY0;Q17RY0-2 Q17RY0 Q17RY0 >sp|Q17RY0|CPEB4_HUMAN Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens GN=CPEB4 PE=1 SV=1;>sp|Q17RY0-2|CPEB4_HUMAN Isoform 2 of Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens GN=CPEB4 0.5 0 0.499853 0 4.17619E-06 99.547 0.5 0 0.0101516 70.556 0.499998 0 0.102354 50.191 0 0 1 S LEKQQLSPSPGQE Proline-directed 0.05 4.17619E-06 99.547 _QQLpSPSPGQEAGILPETEK_ QQLS(0.5)PS(0.5)PGQEAGILPETEK QQLS(0)PS(0)PGQEAGILPET(-70.56)EK 4 3 696.99982 0.21102 265290 0 0 0 198980 0 66308 0 1408 1001 99 99 4695 5333 44644 27379 Mix4_TiO2_1_3 5062 44644 27379 Mix4_TiO2_1_3 5062 Q17RY0;Q17RY0-2 Q17RY0 Q17RY0 >sp|Q17RY0|CPEB4_HUMAN Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens GN=CPEB4 PE=1 SV=1;>sp|Q17RY0-2|CPEB4_HUMAN Isoform 2 of Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens GN=CPEB4 0.908168 9.95173 0.908168 9.95173 4.17619E-06 99.547 0.5 0 0.0101516 70.556 0.499998 0 0.102354 50.191 0 0 1 S KQQLSPSPGQEAG NEK6;Proline-directed 0.05 4.17619E-06 99.547 _QQLSPpSPGQEAGILPETEK_ QQLS(0.092)PS(0.908)PGQEAGILPETEK QQLS(-9.95)PS(9.95)PGQEAGILPET(-84.2)EK 6 2 1044.9961 0.4311 515090 249800 0 0 198980 0 66308 0 1409 1002 185 185 38;5286 49;6017 455 279 Mix4_TiO2_Reinj_1_5 1853 455 279 Mix4_TiO2_Reinj_1_5 1853 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 0.999996 53.7152 0 0 0.999996 53.7152 1.26652E-11 130.68 1 S QGDDQDSEKSKPA 1.26652E-11 130.68 _AAEEQGDDQDpSEKSKPAGSDGER_ AAEEQGDDQDS(1)EKSKPAGSDGER AAEEQGDDQDS(53.72)EKS(-53.72)KPAGS(-104.38)DGER 11 3 829.33655 -0.25121 522700 0.060597 0 0 0 522700 0 0 0 1410 1002 193 193 38;5392 49;6137 52521 32111 Mix4_TiO2_Reinj_1_5 1017 455 279 Mix4_TiO2_Reinj_1_5 1853 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 1 86.0953 0 0 1 86.0953 1.26652E-11 130.68 0.776675 5.41302 0.647122 5.413 0 0 1 S KSKPAGSDGERRG CK2 0.117 1.26652E-11 130.68 _SKPAGpSDGERR_ SKPAGS(1)DGERR S(-86.1)KPAGS(86.1)DGERR 6 2 620.27752 0.060362 141450 0 0 0 92893 0 48559 0 1411 1002 161 161 1473;4854;5285;5286 1656;5517;5518;6014;6017 51263 31404 Mix4_TiO2_Reinj_1_5 3338 13734 8391 Mix4_TiO2_Reinj_1_3 3612 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 1 86.3908 1 85.7718 2.00339E-17 148.05 0.987137 18.8517 0.0845367 54.341 1 86.3908 4.9392E-24 164.76 0 0 0 0 0 0 1 S DEPEERSGDETPG CK2 0.117 4.9392E-24 164.76 _pSGDETPGSEVPGDK_ S(1)GDETPGSEVPGDK S(86.39)GDET(-86.39)PGS(-112.31)EVPGDK 1 2 727.78778 -0.075555 27373000 2.949 6694500 103140 0 20575000 0 0 0 1412 1002 168 168 1473;4854;5285;5286 1656;5517;5518;6014;6017 46561 28520 Mix4_TiO2_Reinj_1_3 3450 13734 8391 Mix4_TiO2_Reinj_1_3 3612 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 0.904198 12.0839 0.00104077 -29.8187 2.00339E-17 148.05 0.00562079 -22.4114 0.0845367 54.341 0.904198 12.0839 4.9392E-24 164.76 0 0 0 0 0 0 1 S GDETPGSEVPGDK 4.9392E-24 164.76 _REEDEPEERSGDETPGpSEVPGDK_ REEDEPEERS(0.04)GDET(0.056)PGS(0.904)EVPGDK REEDEPEERS(-13.56)GDET(-12.08)PGS(12.08)EVPGDK 17 2 1312.5352 0.90509 111310 0.011992 0 0 0 111310 0 0 0 1413 1002 226 226 5403 6149 52638 32180 Mix4_TiO2_Reinj_1_5 8000 52638 32180 Mix4_TiO2_Reinj_1_5 8000 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 0.843257 7.30776 0.491032 0 1.63306E-07 115.08 0 0 0.843257 7.30776 3.76651E-12 133.68 0.498219 0 0.142242 66.452 0 0 0.459957 -0.302014 0.894416 50.03 1 S EAYHSRSKSPLPP 3.76651E-12 133.68 _pSKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK_ S(0.843)KS(0.157)PLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK S(7.31)KS(-7.31)PLPPEEEAKDEEEDQT(-56.98)LVNLDT(-91.16)Y(-95.25)T(-102.34)S(-105.36)DLHFQVS(-115.72)K 1 4 1050.4861 -0.1169 19325000 0 0 0 19325000 0 0 0 1414 1002 228 228 5403 6149 52639 32181 Mix4_TiO2_Reinj_1_5 7982 52638 32180 Mix4_TiO2_Reinj_1_5 8000 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 0.797759 5.97608 0.526449 0.464894 1.63306E-07 115.08 0 0 0.797759 5.97608 3.76651E-12 133.68 0.773725 5.34555 0.142242 66.452 0 0 0.493082 0.302014 0.894416 50.03 1 S YHSRSKSPLPPEE CAMK2;CK1;Proline-directed 0.042 3.76651E-12 133.68 _SKpSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSK_ S(0.201)KS(0.798)PLPPEEEAKDEEEDQT(0.001)LVNLDTYTSDLHFQVSK S(-5.98)KS(5.98)PLPPEEEAKDEEEDQT(-30.54)LVNLDT(-47.2)Y(-47.2)T(-52.02)S(-52.02)DLHFQVS(-62.83)K 3 3 1400.3124 -0.21052 15083000 1913000 0 0 13051000 119230 0 0 1415 1004 1305 1305 89 105 1016 650 Mix4_TiO2_2_2 3050 1015 649 Mix4_InSol_TiO2_1 4177 Q29RF7 Q29RF7 Q29RF7 >sp|Q29RF7|PDS5A_HUMAN Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens GN=PDS5A PE=1 SV=1 1 23.0304 1 23.0304 0.590669 23.03 0 0 1 72.6334 0.0100565 72.633 0 0 1 S AAVGQESPGGLEA Proline-directed 0.05 0.0100565 72.633 _AAVGQEpSPGGLEAGNAK_ AAVGQES(1)PGGLEAGNAK AAVGQES(23.03)PGGLEAGNAK 7 2 818.37234 -1.8721 195780 0 0 0 0 0 195780 0 1416 1007 14 14 1742;4859 1962;5524 15973 9668 Mix4_InSol_TiO2_2 4289 16001 9712 Mix4_TiO2_Reinj_1_5 5473 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.756725 13.9593 0.271958 -3.4231 4.20936E-18 139.89 0.00612913 -17.3474 1.03473 35.923 0.436274 1.19027 2.89985E-35 176.57 0 0 0.756725 13.9593 3.84597E-18 141.33 0.673393 3.60894 2.63345E-08 115.15 1 S RREQGGSGLGSGS GSK3 0.081 2.89985E-35 176.57 _EQGGpSGLGSGSSGGGGSTSGLGSGYIGR_ EQGGS(0.757)GLGS(0.03)GS(0.03)S(0.03)GGGGS(0.03)T(0.03)S(0.03)GLGS(0.03)GY(0.03)IGR EQGGS(13.96)GLGS(-13.96)GS(-13.96)S(-13.96)GGGGS(-13.96)T(-13.96)S(-13.96)GLGS(-13.96)GY(-13.96)IGR 5 2 1233.5301 0.49574 820880 0.10816 0 0 0 0 0 24429 796450 1417 1007 18 18 1742;4859 1962;5524 15971 9663 Mix4_InSol_TiO2_1 5734 16001 9712 Mix4_TiO2_Reinj_1_5 5473 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.893157 10.0326 0.8068 7.76418 4.20936E-18 139.89 0.241038 -1.40053 1.03473 35.923 0.833751 8.0281 2.89985E-35 176.57 0 0 0.893157 10.0326 3.84597E-18 141.33 0.293342 -3.60894 2.63345E-08 115.15 1 S GGSGLGSGSSGGG CK1 0.143 2.89985E-35 176.57 _EQGGSGLGpSGSSGGGGSTSGLGSGYIGR_ EQGGS(0.089)GLGS(0.893)GS(0.016)S(0.002)GGGGSTSGLGSGYIGR EQGGS(-10.03)GLGS(10.03)GS(-17.5)S(-25.92)GGGGS(-49.27)T(-56.67)S(-56.29)GLGS(-77.94)GY(-77.94)IGR 9 2 1233.5301 0.49303 27564000 3.6318 8320100 0 0 16544000 0 2699800 0 1418 1007 20 20 1742;4859 1962;5524 15988 9692 Mix4_TiO2_1_5 4825 16001 9712 Mix4_TiO2_Reinj_1_5 5473 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.799997 6.66057 0.799997 6.66057 4.20936E-18 139.89 0.0360076 -9.65744 1.03473 35.923 0.4314 0 2.89985E-35 176.57 0 0 0.493304 0 3.84597E-18 141.33 0.343522 0 2.63345E-08 115.15 1 S SGLGSGSSGGGGS 2.89985E-35 176.57 _EQGGSGLGSGpSSGGGGSTSGLGSGYIGR_ EQGGSGLGS(0.005)GS(0.8)S(0.173)GGGGS(0.022)TSGLGSGYIGR EQGGS(-41.75)GLGS(-21.88)GS(6.66)S(-6.66)GGGGS(-15.63)T(-37.75)S(-37.18)GLGS(-63.59)GY(-75.64)IGR 11 2 1233.5301 0.14356 1710400 0.22536 1710400 0 0 0 0 0 0 1419 1007 21 21 1742;4859 1962;5524 15977 9675 Mix4_InSol_Tio2_Reinj_1 5742 16001 9712 Mix4_TiO2_Reinj_1_5 5473 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.932611 12.461 0.686916 4.65418 4.20936E-18 139.89 0.200753 -2.19477 1.03473 35.923 0.91613 11.6354 2.89985E-35 176.57 0 0 0.82072 6.89513 3.84597E-18 141.33 0.932611 12.461 2.63345E-08 115.15 1 S GLGSGSSGGGGST CK1 0.081 2.89985E-35 176.57 _EQGGSGLGSGSpSGGGGSTSGLGSGYIGR_ EQGGSGLGS(0.014)GS(0.053)S(0.933)GGGGSTSGLGSGYIGR EQGGS(-37.93)GLGS(-18.15)GS(-12.46)S(12.46)GGGGS(-44.71)T(-61.97)S(-60.7)GLGS(-85.98)GY(-98.85)IGR 12 3 822.68914 -0.22316 16432000 2.1651 530340 0 0 10410000 0 1559600 3932100 1420 1007 26 26 1742;4859 1962;5524 15974 9669 Mix4_InSol_TiO2_2 4335 16001 9712 Mix4_TiO2_Reinj_1_5 5473 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.442135 4.03773 0.230644 -4.05994 4.20936E-18 139.89 0.332766 1.40053 1.03473 35.923 0.111276 -8.44309 2.89985E-35 176.57 0 0 0.442135 4.03773 3.84597E-18 141.33 0.111189 -8.07647 2.63345E-08 115.15 1 S SSGGGGSTSGLGS 2.89985E-35 176.57 _EQGGSGLGSGSSGGGGpSTSGLGSGYIGR_ EQGGS(0.006)GLGS(0.174)GS(0.174)S(0.174)GGGGS(0.442)T(0.013)S(0.015)GLGSGYIGR EQGGS(-18.76)GLGS(-4.04)GS(-4.04)S(-4.04)GGGGS(4.04)T(-15.36)S(-14.56)GLGS(-35.49)GY(-42.4)IGR 17 3 822.68914 0.10189 0 0 0 0 0 0 0 0 0 1421 1007 637 637 2836;4916 3230;5589 27064 16912 Mix4_TiO2_1_1 6361 27080 16940 Mix4_TiO2_Reinj_1_5 7639 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 1 81.6281 1 81.6281 3.44873E-20 179.41 0.999998 57.3915 8.90566E-18 175.6 1 67.4914 3.57167E-26 203.31 0.980552 17.7783 0.0515112 56.334 0.999749 36.0297 3.35294E-09 128.23 0.998068 27.1602 3.52237E-06 111.42 1 S GHRRILSDVTHSA CAMK2 0.042 3.57167E-26 203.31 _ILpSDVTHSAVFGVPASK_ ILS(1)DVTHSAVFGVPASK ILS(81.63)DVT(-81.63)HS(-113.06)AVFGVPAS(-179.41)K 3 2 904.45313 0.36792 35226000 7046900 1026200 0 23436000 64413 2026900 1626500 1422 1007 642 642 2836;4916 3230;5589 27069 16922 Mix4_TiO2_1_5 6820 27080 16940 Mix4_TiO2_Reinj_1_5 7639 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.563469 1.48623 0.563469 1.48623 3.44873E-20 179.41 0.12851 -7.8465 8.90566E-18 175.6 0.510354 1.11735 3.57167E-26 203.31 0.0980647 -8.99618 0.0515112 56.334 0.0778979 -8.40566 3.35294E-09 128.23 0.110245 -8.49463 3.52237E-06 111.42 1 S LSDVTHSAVFGVP 3.57167E-26 203.31 _ILSDVTHpSAVFGVPASK_ ILS(0.4)DVT(0.036)HS(0.563)AVFGVPASK ILS(-1.49)DVT(-11.9)HS(1.49)AVFGVPAS(-119.26)K 8 3 603.30451 -0.44022 1739700 1380300 0 0 359480 0 0 0 1423 1007 731 731 3444 3889 32480 20143 Mix4_TiO2_Reinj_1_5 8325 32481 20145 Mix4_TiO2_Reinj_1_5 8265 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.992154 21.0892 0.945054 12.3831 0.0119322 76.318 0.49866 0 1.17968 39.847 0.992154 21.0892 0.0102021 76.802 0.974395 15.8268 0.0253658 72.562 0 0 0 0 1 S PEKLGGSAESLIP NEK6 0.076 0.0102021 76.802 _LGGpSAESLIPGFQSTQGDAFATTSFSAGTAEK_ LGGS(0.992)AES(0.008)LIPGFQSTQGDAFATTSFSAGTAEK LGGS(21.09)AES(-21.09)LIPGFQS(-44.43)T(-44.43)QGDAFAT(-44.11)T(-49.38)S(-54.34)FS(-67.3)AGT(-69.74)AEK 4 3 1071.8256 0.60335 7037800 1275100 0 0 5638200 124460 0 0 1424 1007 734 734 3444 3889 32476 20136 Mix4_TiO2_1_6 6351 32481 20145 Mix4_TiO2_Reinj_1_5 8265 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.873226 8.3844 0.873226 8.3844 0.0119322 76.318 0.746852 6.34206 1.17968 39.847 0.408162 -1.34434 0.0102021 76.802 0.0878062 -10.1462 0.0253658 72.562 0 0 0 0 1 S LGGSAESLIPGFQ CK1 0.081 0.0102021 76.802 _LGGSAEpSLIPGFQSTQGDAFATTSFSAGTAEK_ LGGS(0.127)AES(0.873)LIPGFQSTQGDAFATTSFSAGTAEK LGGS(-8.38)AES(8.38)LIPGFQS(-43.88)T(-43.88)QGDAFAT(-49.76)T(-49.76)S(-49.5)FS(-60.54)AGT(-68.36)AEK 7 3 1071.8256 -0.068657 199270 154070 45193 0 0 0 0 0 1425 1007 846 846 3634 4095 34162 21068 Mix4_TiO2_Reinj_1_5 3679 34161 21067 Mix4_TiO2_1_5 2984 Q2M2I8 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3 0.995727 23.7085 0.97415 15.7635 0.0039542 88.724 0.995727 23.7085 0.0130784 67.671 1 S VPQRLPSQTESVT CAMK2;CK2;GSK3 0.042 0.0039542 88.724 _LPpSQTESVTSNR_ LPS(0.996)QT(0.004)ESVTSNR LPS(23.71)QT(-23.71)ES(-44.79)VT(-67.67)S(-67.67)NR 3 2 699.81667 -0.18513 336220 20.024 85279 0 0 250940 0 0 0 1426 1007 670 670 5128;5398 5833;5834;6143;6144 52585 32155 Mix4_InSol_Tio2_Reinj_1 1703 52582 32150 Mix4_InSol_TiO2_1 1436 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.97973 17.1727 0.918773 10.5746 0.00997262 73.292 0.017065 -17.1995 0.39631 17.199 0.758306 5.13725 0.00694284 69.94 0.925674 10.9559 4.4342E-06 141.24 0.97973 17.1727 0.000297962 109.6 2 S SLNKSKSATTTPS CHK1;PKD 0.020748 0.000296126 109.67 _SKpSATTTPSGpSPR_ S(0.019)KS(0.98)AT(0.002)TTPS(0.013)GS(0.987)PR S(-17.17)KS(17.17)AT(-27.86)T(-46.05)T(-36.09)PS(-18.71)GS(18.71)PR 3 2 718.79455 0.22414 433820 61243 0 0 243860 0 0 128720 1427 1007 676 676 5128;5398 5833;5834;6143;6144 49620 30315 Mix4_TiO2_1_3 1169 49625 30327 Mix4_TiO2_Reinj_1_5 1882 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.989888 20.128 0.989888 20.128 0.0226287 56.753 0.895472 13.9252 0.39631 17.199 0.504134 0.0771052 0.00658419 70.823 0.758023 5.05195 0.0521499 47.998 0.819083 6.57864 0.0272825 55.373 1 S SATTTPSGSPRTS CK1 0.143 0.00658419 70.823 _SATTTPpSGSPR_ SATTTPS(0.99)GS(0.01)PR S(-48)AT(-48)T(-48)T(-33.39)PS(20.13)GS(-20.13)PR 7 2 571.24789 -0.30334 1324700 494390 70913 0 171620 0 123680 464130 1428 1007 678 678 5128;5398 5833;5834;6143;6144 49625 30327 Mix4_TiO2_Reinj_1_5 1882 49625 30327 Mix4_TiO2_Reinj_1_5 1882 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.993807 22.0635 0.882033 8.77601 0.0226287 56.753 0.0362685 -13.9252 0.39631 17.199 0.993807 22.0635 0.00658419 70.823 0.781783 5.63264 0.0521499 47.998 0.977154 16.3529 0.0272825 55.373 1 S TTTPSGSPRTSQQ CDK1;CK1;GSK3;Proline-directed 0.0057 0.00658419 70.823 _SATTTPSGpSPR_ SATTTPS(0.006)GS(0.994)PR S(-70.82)AT(-70.82)T(-67.44)T(-48.87)PS(-22.06)GS(22.06)PR 9 2 571.24789 -0.20664 2685400 23036 0 0 2096900 0 493460 71958 1429 1007 668 668 5398 6143;6144 52583 32153 Mix4_InSol_TiO2_1 1673 52582 32150 Mix4_InSol_TiO2_1 1436 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.659019 2.87902 0.313068 -2.47204 0.0268476 58.66 0.232219 -5.13725 0.0766808 45.095 0.659019 2.87902 0.000296126 109.67 0.0847271 -10.3382 0.000111833 116 2 S EASLNKSKSATTT CK1;NEK6 0.076 0.000296126 109.67 _pSKSATTTPSGpSPR_ S(0.659)KS(0.341)ATTTPS(0.009)GS(0.991)PR S(2.88)KS(-2.88)AT(-41.18)T(-40.7)T(-39.72)PS(-21.28)GS(21.28)PR 1 2 718.79455 0.24996 134160 0 0 0 0 0 134160 0 1430 1007 652 652 5799 6605 57112 34835 Mix4_TiO2_1_5 6228 57113 34836 Mix4_TiO2_Reinj_1_5 7054 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.5 0 0.5 0 0.0183783 66.131 0 0 0.420115 -1.39974 5.48738E-26 206.77 1 S GVPASKSTQLLQA 5.48738E-26 206.77 _pSTQLLQAAAAEASLNK_ S(0.5)T(0.5)QLLQAAAAEASLNK S(0)T(0)QLLQAAAAEAS(-66.13)LNK 1 3 565.94862 -0.29843 38919 0.41761 38919 0 0 0 0 0 0 1431 1007 682 682 6232 7120 61787 37442 Mix4_TiO2_1_5 7158 61787 37442 Mix4_TiO2_1_5 7158 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.536912 0.717063 0.536912 0.717063 5.64525E-07 100.2 0 0 1 S SGSPRTSQQNVYN CK1;PKA 0.042 5.64525E-07 100.2 _TpSQQNVYNPSEGSTWNPFDDDNFSK_ T(0.455)S(0.537)QQNVY(0.008)NPSEGSTWNPFDDDNFSK T(-0.72)S(0.72)QQNVY(-18.38)NPS(-37.72)EGS(-75.31)T(-79.93)WNPFDDDNFS(-100.2)K 2 2 1479.0985 0.73987 82438 0.0048003 82438 0 0 0 0 0 0 1432 1007 618 618 6418;6419 7340;7341;7342;7343 64799 39769 Mix4_InSol_TiO2_2 2880 64768 39754 Mix4_TiO2_Reinj_1_5 3877 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.878926 8.79142 0.77065 6.26027 0.0313194 54.175 0.316132 1.42017 0.723626 1.4202 0.779026 1.83388 0.71845 1.8339 0.0667689 -15.7761 0.426591 15.776 0.878926 8.79142 0.0307815 54.335 0.422501 -1.90413 0.0106764 60.755 2 S QGQKVGSLTPPSS 0.0106764 60.755 _VGpSLTPPpSSPKTQR_ VGS(0.879)LT(0.119)PPS(0.541)S(0.456)PKT(0.005)QR VGS(8.79)LT(-8.79)PPS(0.75)S(-0.75)PKT(-26.1)QR 3 2 807.86805 0.39382 689780 182430 0 0 325810 0 181540 0 1433 1007 623 623 6418;6419 7340;7341;7342;7343 64766 39746 Mix4_TiO2_Reinj_1_1 3319 64768 39754 Mix4_TiO2_Reinj_1_5 3877 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.969482 14.8468 0.956396 11.5736 0.0313194 54.175 0.694399 3.43427 0.443562 14.979 0.969482 14.8468 0.0106764 60.755 0.91455 13.1295 0.426591 15.776 0.799576 3.87179 0.0307815 54.335 0.613403 1.99135 0.0106764 60.755 2 S GSLTPPSSPKTQR 0.0106764 60.755 _VGSLTPPpSpSPK_ VGSLT(0.072)PPS(0.969)S(0.958)PK VGS(-40.28)LT(-13.5)PPS(14.85)S(13.5)PK 8 2 615.26437 0.53097 35475000 4869100 332610 0 20877000 50702 8520700 825210 1434 1007 624 624 6418;6419 7340;7341;7342;7343 64766 39746 Mix4_TiO2_Reinj_1_1 3319 64768 39754 Mix4_TiO2_Reinj_1_5 3877 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.958403 13.4991 0.474218 0 0.0313194 54.175 0.371393 -3.43427 0.443562 14.979 0.958403 13.4991 0.0106764 60.755 0.904716 12.1945 0.426591 15.776 0.689041 1.96408 0.0307815 54.335 0.851064 7.6772 0.0106764 60.755 2 S SLTPPSSPKTQRA CDK1;CK1;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0106764 60.755 _VGSLTPPpSpSPK_ VGSLT(0.072)PPS(0.969)S(0.958)PK VGS(-40.28)LT(-13.5)PPS(14.85)S(13.5)PK 9 2 615.26437 0.53097 14397000 0 0 0 6141700 50702 1120700 7084400 1435 1008 7 7 606 697 5770 3409 Mix4_TiO2_Reinj_1_5 7569 5770 3409 Mix4_TiO2_Reinj_1_5 7569 Q2M389;Q2M389-2 Q2M389 Q2M389 >sp|Q2M389|WAHS7_HUMAN WASH complex subunit 7 OS=Homo sapiens GN=KIAA1033 PE=1 SV=2;>sp|Q2M389-2|WAHS7_HUMAN Isoform 2 of WASH complex subunit 7 OS=Homo sapiens GN=KIAA1033 0.999959 44.2591 0.999719 36.42 0.0998655 51.053 0.999959 44.2591 0.00981309 69.189 1 S MAVETLSPDWEFD Proline-directed 0.05 0.00981309 69.189 _(ac)AVETLpSPDWEFDRVDDGSQK_ AVETLS(1)PDWEFDRVDDGSQK AVET(-44.26)LS(44.26)PDWEFDRVDDGS(-54.04)QK 6 3 806.0162 -0.031422 320730 1.1101 91054 0 0 229670 0 0 0 1436 1009 133 133 4478 5089 42473 26120 Mix4_TiO2_Reinj_1_5 9141 42473 26120 Mix4_TiO2_Reinj_1_5 9141 Q2M3G4;Q2M3G4-2 Q2M3G4 Q2M3G4 >sp|Q2M3G4|SHRM1_HUMAN Protein Shroom1 OS=Homo sapiens GN=SHROOM1 PE=1 SV=1;>sp|Q2M3G4-2|SHRM1_HUMAN Isoform 2 of Protein Shroom1 OS=Homo sapiens GN=SHROOM1 0.841126 7.2381 0.841126 7.2381 0.0271879 65.982 1 S QAAEPPSPPASRA ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.0271879 65.982 _QATPLLYALAAEAEAAAQAAEPPpSPPASR_ QATPLLYALAAEAEAAAQAAEPPS(0.841)PPAS(0.159)R QAT(-65.98)PLLY(-65.98)ALAAEAEAAAQAAEPPS(7.24)PPAS(-7.24)R 24 3 981.48137 -0.5317 115220 0 0 0 115220 0 0 0 1437 1009 49 49 6184 7061 61243 37099 Mix4_TiO2_Reinj_1_5 8975 61243 37099 Mix4_TiO2_Reinj_1_5 8975 Q2M3G4;Q2M3G4-2 Q2M3G4 Q2M3G4 >sp|Q2M3G4|SHRM1_HUMAN Protein Shroom1 OS=Homo sapiens GN=SHROOM1 PE=1 SV=1;>sp|Q2M3G4-2|SHRM1_HUMAN Isoform 2 of Protein Shroom1 OS=Homo sapiens GN=SHROOM1 0.920895 10.663 0 0 0.920895 10.663 0.000240689 95.974 1 S PEPRTQSPGTDLL CAMK2;Proline-directed 0.042 0.000240689 95.974 _TQpSPGTDLLPYLDWDYVR_ T(0.079)QS(0.921)PGTDLLPYLDWDYVR T(-10.66)QS(10.66)PGT(-42.39)DLLPY(-95.97)LDWDY(-95.97)VR 3 2 1110.0065 1.5159 112010 0 0 0 112010 0 0 0 1438 1013 460 460 3709 4182 34976 21667 Mix4_TiO2_Reinj_1_5 4149 34976 21667 Mix4_TiO2_Reinj_1_5 4149 Q3KQU3;Q3KQU3-4;Q3KQU3-2 Q3KQU3 Q3KQU3 >sp|Q3KQU3|MA7D1_HUMAN MAP7 domain-containing protein 1 OS=Homo sapiens GN=MAP7D1 PE=1 SV=1;>sp|Q3KQU3-4|MA7D1_HUMAN Isoform 4 of MAP7 domain-containing protein 1 OS=Homo sapiens GN=MAP7D1;>sp|Q3KQU3-2|MA7D1_HUMAN Isoform 2 of MAP7 domain-containing protei 0.999695 35.2198 0.997508 28.2456 0.162205 34.771 0 0 0.999695 35.2198 0.0107367 71.901 0.803569 12.1387 0.37595 12.139 0.938436 17.8513 0.411212 17.851 1 S STASELSPKSKAR CDK1;CK1;Proline-directed 0.0057 0.0107367 71.901 _LSASTASELpSPK_ LSASTASELS(1)PK LS(-71.9)AS(-67.53)T(-53.44)AS(-35.22)ELS(35.22)PK 10 2 635.79996 -1.3511 308690 59111 0 0 238560 0 0 11024 1439 1013 70 70 4628 5252 43870 26889 Mix4_TiO2_Reinj_1_5 5816 43870 26889 Mix4_TiO2_Reinj_1_5 5816 Q3KQU3;Q3KQU3-4;Q3KQU3-2 Q3KQU3 Q3KQU3 >sp|Q3KQU3|MA7D1_HUMAN MAP7 domain-containing protein 1 OS=Homo sapiens GN=MAP7D1 PE=1 SV=1;>sp|Q3KQU3-4|MA7D1_HUMAN Isoform 4 of MAP7 domain-containing protein 1 OS=Homo sapiens GN=MAP7D1;>sp|Q3KQU3-2|MA7D1_HUMAN Isoform 2 of MAP7 domain-containing protei 0.978037 16.4866 0.978037 16.4866 0.0178102 66.61 1 S LPLEPESPSGQVG ERK/MAPK;Proline-directed;WW GroupIV 0.000145 0.0178102 66.61 _QLPLEPEpSPSGQVGPR_ QLPLEPES(0.978)PS(0.022)GQVGPR QLPLEPES(16.49)PS(-16.49)GQVGPR 8 2 885.92474 -0.21485 106230 0 0 0 106230 0 0 0 1440 1013 112 112 5049 5743 48811 29834 Mix4_TiO2_Reinj_1_4 3493 48811 29834 Mix4_TiO2_Reinj_1_4 3493 Q3KQU3;Q3KQU3-4;Q3KQU3-2 Q3KQU3 Q3KQU3 >sp|Q3KQU3|MA7D1_HUMAN MAP7 domain-containing protein 1 OS=Homo sapiens GN=MAP7D1 PE=1 SV=1;>sp|Q3KQU3-4|MA7D1_HUMAN Isoform 4 of MAP7 domain-containing protein 1 OS=Homo sapiens GN=MAP7D1;>sp|Q3KQU3-2|MA7D1_HUMAN Isoform 2 of MAP7 domain-containing protei 0.736444 6.72928 0 0 0.736444 6.72928 0.105991 49.744 1 S ARPPRRSSQPSPT GSK3;PKA 0.042 0.105991 49.744 _RpSSQPSPTAVPASDSPPTK_ RS(0.736)S(0.156)QPS(0.103)PT(0.004)AVPASDSPPTK RS(6.73)S(-6.73)QPS(-8.55)PT(-22.36)AVPAS(-49.74)DS(-49.74)PPT(-49.74)K 2 3 663.98076 0.11462 53307 0 0 0 53307 0 0 0 1441 1014 197 197 5606 6389 54827 33573 Mix4_InSol_Tio2_Reinj_1 2966 54827 33573 Mix4_InSol_Tio2_Reinj_1 2966 Q3MHD2-2;Q3MHD2 Q3MHD2-2 Q3MHD2-2 >sp|Q3MHD2-2|LSM12_HUMAN Isoform 2 of Protein LSM12 homolog OS=Homo sapiens GN=LSM12;>sp|Q3MHD2|LSM12_HUMAN Protein LSM12 homolog OS=Homo sapiens GN=LSM12 PE=1 SV=2 0.575707 1.32535 0.554862 0.961743 0.313761 30.492 0.575707 1.32535 0.00229386 86.306 1 S QKEAALSS_____ 0.00229386 86.306 _SQAQQPQKEAALpSS_ SQAQQPQKEAALS(0.576)S(0.424) S(-86.31)QAQQPQKEAALS(1.33)S(-1.33) 13 2 776.85378 0.78208 128770 0 0 0 0 0 50235 78531 1442 1017 12 12 4820 5470 46029 28153 Mix4_TiO2_Reinj_1_1 3620 46029 28153 Mix4_TiO2_Reinj_1_1 3620 Q499Y3 Q499Y3 Q499Y3 >sp|Q499Y3|YJ016_HUMAN Putative uncharacterized protein C10orf88-like OS=Homo sapiens PE=2 SV=2 0.689055 6.48614 0.689055 6.48614 0.097312 49.648 2 S ANYSTGSPAVKSR CK1;Proline-directed 0.05 0.097312 49.648 _(ac)RAVSANYSpTGpSPAVKSR_ RAVS(0.106)ANY(0.106)S(0.271)T(0.827)GS(0.689)PAVKSR RAVS(-11.21)ANY(-11.21)S(-6.49)T(11.21)GS(6.49)PAVKS(-49.65)R 11 2 976.93499 -0.018959 250820 0 0 0 250820 0 0 0 1443 1019 1029 1029 3552 4006 33527 20665 Mix4_TiO2_Reinj_1_5 5700 33527 20665 Mix4_TiO2_Reinj_1_5 5700 Q52LW3 Q52LW3 Q52LW3 >sp|Q52LW3|RHG29_HUMAN Rho GTPase-activating protein 29 OS=Homo sapiens GN=ARHGAP29 PE=1 SV=2 1 65.7513 1 46.2932 0.0491178 46.293 1 65.7513 0.00522209 65.751 0 0 0 0 1 S DRLLLASPPNERN NEK6;Proline-directed 0.05 0.00522209 65.751 _LLLApSPPNER_ LLLAS(1)PPNER LLLAS(65.75)PPNER 5 2 595.30247 0.019369 148680 22369 0 0 126310 0 0 0 1444 1019 913 913 4428 5038 42131 25958 Mix4_TiO2_Reinj_1_5 4748 42131 25958 Mix4_TiO2_Reinj_1_5 4748 Q52LW3 Q52LW3 Q52LW3 >sp|Q52LW3|RHG29_HUMAN Rho GTPase-activating protein 29 OS=Homo sapiens GN=ARHGAP29 PE=1 SV=2 1 52.5648 1 22.565 0.258913 22.565 1 52.5648 0.0717088 52.565 1 S FPKPLLSPEERDI CK2;Proline-directed 0.05 0.0717088 52.565 _PLLpSPEER_ PLLS(1)PEER PLLS(52.56)PEER 4 2 510.74171 -1.6422 72474 0 0 0 72474 0 0 0 1445 1020 208 208 3614 4074 34010 21009 Mix4_TiO2_1_5 3709 34007 21004 Mix4_InSol_TiO2_1 4734 Q53EP0;Q53EP0-2 Q53EP0 Q53EP0 >sp|Q53EP0|FND3B_HUMAN Fibronectin type III domain-containing protein 3B OS=Homo sapiens GN=FNDC3B PE=1 SV=2;>sp|Q53EP0-2|FND3B_HUMAN Isoform 2 of Fibronectin type III domain-containing protein 3B OS=Homo sapiens GN=FNDC3B 0.993709 22.0667 0.993709 22.0667 0.0526844 45.112 0 0 0.991423 23.6723 0.0625551 41.844 0.993158 23.3366 0.0402349 49.234 0.942617 14.9608 0.281344 23.046 1 S RQNRLNSPPSSIY CAMK2;GSK3;Proline-directed 0.042 0.0402349 49.234 _LNpSPPSSIYK_ LNS(0.994)PPS(0.006)SIYK LNS(22.07)PPS(-22.07)S(-40.62)IY(-45.11)K 3 2 593.2812 0.42866 910000 172710 0 0 562120 0 92939 82238 1446 1022 428 428 5588 6369 54668 33478 Mix4_TiO2_Reinj_1_4 5884 54668 33478 Mix4_TiO2_Reinj_1_4 5884 Q53EZ4 Q53EZ4 Q53EZ4 >sp|Q53EZ4|CEP55_HUMAN Centrosomal protein of 55 kDa OS=Homo sapiens GN=CEP55 PE=1 SV=3 0.979032 16.6924 0.979032 16.6924 2.80707E-09 144.68 1 S VAASPKSPTAALN CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.80707E-09 144.68 _pSPTAALNESLVECPK_ S(0.979)PT(0.021)AALNESLVECPK S(16.69)PT(-16.69)AALNES(-128.3)LVECPK 1 2 848.3866 0.74542 135090 0 0 0 135090 0 0 0 1447 1023 135 135 5889;5890 6716;6717 58080 35277 Mix4_InSol_TiO2_1 5860 58086 35287 Mix4_TiO2_Reinj_1_2 4694 Q53GA4 Q53GA4 Q53GA4 >sp|Q53GA4|PHLA2_HUMAN Pleckstrin homology-like domain family A member 2 OS=Homo sapiens GN=PHLDA2 PE=1 SV=2 0.524846 4.26375 0.447998 0 0.000270357 88.547 0 0 0.357473 0 4.63986E-08 113.44 0 0 0.524846 4.26375 1.89335 22.781 0.201739 -3.20532 1.92796 21.751 1 S AAAAAPSEPSEPS 4.63986E-08 113.44 _TAPAAPAEDAVAAAAAAPpSEPSEPSRPSPQPKPR_ T(0.003)APAAPAEDAVAAAAAAPS(0.525)EPS(0.197)EPS(0.197)RPS(0.079)PQPKPR T(-22.78)APAAPAEDAVAAAAAAPS(4.26)EPS(-4.26)EPS(-4.26)RPS(-8.22)PQPKPR 19 4 843.91095 -0.42537 436460 0 0 0 0 0 436460 0 1448 1023 138 138 5889;5890 6716;6717 58083 35282 Mix4_TiO2_1_6 3953 58086 35287 Mix4_TiO2_Reinj_1_2 4694 Q53GA4 Q53GA4 Q53GA4 >sp|Q53GA4|PHLA2_HUMAN Pleckstrin homology-like domain family A member 2 OS=Homo sapiens GN=PHLDA2 PE=1 SV=2 0.480957 0 0.480957 0 0.000270357 88.547 0 0 0.468502 0.850098 4.63986E-08 113.44 0 0 0.196633 -4.26375 1.89335 22.781 0.186716 -3.54141 1.92796 21.751 1 S AAPSEPSEPSRPS CK1 0.081 4.63986E-08 113.44 _TAPAAPAEDAVAAAAAAPSEPpSEPSRPSPQPKPR_ TAPAAPAEDAVAAAAAAPS(0.008)EPS(0.481)EPS(0.481)RPS(0.03)PQPKPR T(-84.08)APAAPAEDAVAAAAAAPS(-17.56)EPS(0)EPS(0)RPS(-12.1)PQPKPR 22 3 1124.8788 -0.018989 0 0 0 0 0 0 0 0 1449 1023 141 141 5889;5890 6716;6717 58087 35289 Mix4_TiO2_Reinj_1_6 4610 58086 35287 Mix4_TiO2_Reinj_1_2 4694 Q53GA4 Q53GA4 Q53GA4 >sp|Q53GA4|PHLA2_HUMAN Pleckstrin homology-like domain family A member 2 OS=Homo sapiens GN=PHLDA2 PE=1 SV=2 0.670475 6.57056 0.480957 0 0.000270357 88.547 0 0 0.670475 6.57056 4.63986E-08 113.44 0 0 0.196633 -4.26375 1.89335 22.781 0.186716 -3.54141 1.92796 21.751 1 S SEPSEPSRPSPQP CK1 0.081 4.63986E-08 113.44 _TAPAAPAEDAVAAAAAAPSEPSEPpSRPSPQPKPR_ TAPAAPAEDAVAAAAAAPS(0.034)EPS(0.148)EPS(0.67)RPS(0.148)PQPKPR T(-76.31)APAAPAEDAVAAAAAAPS(-12.93)EPS(-6.57)EPS(6.57)RPS(-6.57)PQPKPR 25 3 1124.8788 -0.12761 4674600 0 0 0 4674600 0 0 0 1450 1023 144 144 5889;5890 6716;6717 58075 35269 Mix4_TiO2_1_6 4075 58086 35287 Mix4_TiO2_Reinj_1_2 4694 Q53GA4 Q53GA4 Q53GA4 >sp|Q53GA4|PHLA2_HUMAN Pleckstrin homology-like domain family A member 2 OS=Homo sapiens GN=PHLDA2 PE=1 SV=2 0.885645 9.65579 0.885645 9.65579 0.000270357 88.547 0 0 0.828889 7.58574 4.63986E-08 113.44 0 0 0.0791215 -8.21737 1.89335 22.781 0.422009 3.20532 1.92796 21.751 1 S SEPSRPSPQPKPR CK1;PKA;Proline-directed 0.042 4.63986E-08 113.44 _TAPAAPAEDAVAAAAAAPSEPSEPSRPpSPQPK_ TAPAAPAEDAVAAAAAAPS(0.001)EPS(0.017)EPS(0.096)RPS(0.886)PQPK T(-58.34)APAAPAEDAVAAAAAAPS(-29.42)EPS(-17.05)EPS(-9.66)RPS(9.66)PQPK 28 3 1040.4942 -0.39738 1521600 389670 0 0 1131900 0 0 0 1451 1027 21 21 6057 6909 59801 36272 Mix4_TiO2_Reinj_1_6 6975 59801 36272 Mix4_TiO2_Reinj_1_6 6975 Q53H80 Q53H80 Q53H80 >sp|Q53H80|AKIR2_HUMAN Akirin-2 OS=Homo sapiens GN=AKIRIN2 PE=1 SV=2 0.999501 33.744 0.943424 12.9076 0.527708 20.568 0.999501 33.744 0.104158 41.144 1 S PLLSPASPKRRRC CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.104158 41.144 _TLDFDPLLSPApSPK_ TLDFDPLLSPAS(1)PK T(-41.14)LDFDPLLS(-33.74)PAS(33.74)PK 12 2 790.88402 -0.067361 31884 9019.9 0 0 22864 0 0 0 1452 1028 219 219 2950 3357 28149 17507 Mix4_TiO2_Reinj_1_2 4538 28148 17506 Mix4_TiO2_1_2 3814 Q53HL2 Q53HL2 Q53HL2 >sp|Q53HL2|BOREA_HUMAN Borealin OS=Homo sapiens GN=CDCA8 PE=1 SV=2 1 67.3533 1 67.5687 5.53859E-16 177.48 1 67.3533 5.84339E-12 166.8 0 0 0 0 1 S NISGNGSPLADSK CK1;Proline-directed 0.05 5.53859E-16 177.48 _IYNISGNGpSPLADSK_ IYNISGNGS(1)PLADSK IY(-146.17)NIS(-67.35)GNGS(67.35)PLADS(-97.37)K 9 2 808.37181 0.40322 579900 167500 0 0 412400 0 0 0 1453 1031 268 268 2908;2909 3312;3313 27829 17332 Mix4_TiO2_1_3 2685 27830 17333 Mix4_TiO2_Reinj_1_3 3239 Q5BKZ1 Q5BKZ1 Q5BKZ1 >sp|Q5BKZ1|ZN326_HUMAN Zinc finger protein 326 OS=Homo sapiens GN=ZNF326 PE=1 SV=2 0.618503 7.9122 0.618503 7.9122 0.105733 38.351 0.0141931 -17.9464 0.00357042 84.952 9.79525E-05 -38.6447 0.128937 38.645 0.00445099 -23.0251 0.379521 23.025 1 S MEKISLSKSPTKT 0.00357042 84.952 _ISLpSKSPTKTDPK_ IS(0.1)LS(0.619)KS(0.1)PT(0.091)KT(0.091)DPK IS(-7.91)LS(7.91)KS(-7.91)PT(-8.34)KT(-8.34)DPK 4 3 494.59188 -0.24347 131000 131000 0 0 0 0 0 0 1454 1031 270 270 2908;2909;5591 3312;3313;6372 54687 33483 Mix4_TiO2_Reinj_1_3 1649 54687 33483 Mix4_TiO2_Reinj_1_3 1649 Q5BKZ1 Q5BKZ1 Q5BKZ1 >sp|Q5BKZ1|ZN326_HUMAN Zinc finger protein 326 OS=Homo sapiens GN=ZNF326 PE=1 SV=2 0.983804 17.8364 0.800369 7.44398 0.105733 38.351 0.983804 17.8364 5.09184E-05 113.84 0.000675391 -30.2593 0.128937 38.645 0.0857382 -10.1779 0.379521 23.025 1 S KISLSKSPTKTDP CDK1;CDK2;CK1;NEK6;Proline-directed 0.0057 5.09184E-05 113.84 _pSPTKTDPKNEEEEK_ S(0.984)PT(0.016)KTDPKNEEEEK S(17.84)PT(-17.84)KT(-52.75)DPKNEEEEK 1 2 856.37475 0.075601 1122200 364830 0 0 757370 0 0 0 1455 1032 857 857 650 748 6259 3739 Mix4_TiO2_1_5 2364 6258 3738 Mix4_InSol_Tio2_Reinj_1 3098 Q5H9R7-5;Q5H9R7;Q5H9R7-2;Q5H9R7-6;Q5H9R7-4 Q5H9R7-5 Q5H9R7-5 >sp|Q5H9R7-5|PP6R3_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3;>sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3 PE=1 SV=2;>sp|Q5H9R7-2| 0.475461 0 0.475461 0 0.886863 9.8623 0 0 0 0 0 0 0 0 0.442901 0 0.0510714 53.753 1 S AAPRPPSSSPEQR CAMK2 0.042 0.0510714 53.753 _CAAPRPPpSSSPEQR_ CAAPRPPS(0.475)S(0.475)S(0.049)PEQR CAAPRPPS(0)S(0)S(-9.86)PEQR 8 2 810.35343 0.30652 0 0 0 0 0 0 0 0 1456 1032 858 858 650 748 6259 3739 Mix4_TiO2_1_5 2364 6258 3738 Mix4_InSol_Tio2_Reinj_1 3098 Q5H9R7-5;Q5H9R7;Q5H9R7-2;Q5H9R7-6;Q5H9R7-4 Q5H9R7-5 Q5H9R7-5 >sp|Q5H9R7-5|PP6R3_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3;>sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3 PE=1 SV=2;>sp|Q5H9R7-2| 0.475461 0 0.475461 0 0.886863 9.8623 0 0 0 0 0 0 0 0 0.442901 0 0.0510714 53.753 1 S APRPPSSSPEQRT CK2 0.117 0.0510714 53.753 _CAAPRPPpSSSPEQR_ CAAPRPPS(0.475)S(0.475)S(0.049)PEQR CAAPRPPS(0)S(0)S(-9.86)PEQR 9 2 810.35343 0.30652 0 0 0 0 0 0 0 0 1457 1032 617 617 2889 3291 27683 17270 Mix4_TiO2_Reinj_1_5 6800 27677 17263 Mix4_TiO2_1_5 6030 Q5H9R7-5;Q5H9R7;Q5H9R7-2;Q5H9R7-6;Q5H9R7-4;Q5H9R7-3 Q5H9R7-5 Q5H9R7-5 >sp|Q5H9R7-5|PP6R3_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3;>sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3 PE=1 SV=2;>sp|Q5H9R7-2| 1 142.678 1 116.238 1.50678E-31 207.01 1 159.939 7.46691E-21 159.94 1 142.678 1.22122E-25 177.95 0 0 1 124.273 7.68142E-21 159.48 1 42.9952 2.98876E-16 154.95 1 S QFDDGGSDEEDIW CK2 0.117 1.50678E-31 207.01 _IQQFDDGGpSDEEDIWEEK_ IQQFDDGGS(1)DEEDIWEEK IQQFDDGGS(142.68)DEEDIWEEK 9 3 740.6266 0.0090855 12734000 14.422 3101400 110820 0 8704500 0 423670 393690 1458 1032 523 523 4353 4951 41295 25399 Mix4_TiO2_Reinj_2_1 4202 41294 25398 Mix4_TiO2_Reinj_1_6 5351 Q5H9R7-5;Q5H9R7;Q5H9R7-2 Q5H9R7-5 Q5H9R7-5 >sp|Q5H9R7-5|PP6R3_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3;>sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3 PE=1 SV=2;>sp|Q5H9R7-2| 0.333276 0 0.279503 0 0.979264 27.54 0 0 0.331898 0 5.25139E-07 107.76 0.333276 0 7.69533E-07 102.95 1 S TTCHIHSSSDDEI CK2 0.117 5.25139E-07 107.76 _NTVDLVTTCHIHpSSSDDEIDFK_ NTVDLVTTCHIHS(0.333)S(0.333)S(0.333)DDEIDFK NT(-93.26)VDLVT(-41.98)T(-33.41)CHIHS(0)S(0)S(0)DDEIDFK 13 3 871.71067 0.059307 0 0 0 0 0 0 0 0 1459 1032 524 524 4353 4951 41295 25399 Mix4_TiO2_Reinj_2_1 4202 41294 25398 Mix4_TiO2_Reinj_1_6 5351 Q5H9R7-5;Q5H9R7;Q5H9R7-2 Q5H9R7-5 Q5H9R7-5 >sp|Q5H9R7-5|PP6R3_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3;>sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3 PE=1 SV=2;>sp|Q5H9R7-2| 0.333276 0 0.279503 0 0.979264 27.54 0 0 0.331898 0 5.25139E-07 107.76 0.333276 0 7.69533E-07 102.95 1 S TCHIHSSSDDEID CK2 0.117 5.25139E-07 107.76 _NTVDLVTTCHIHpSSSDDEIDFK_ NTVDLVTTCHIHS(0.333)S(0.333)S(0.333)DDEIDFK NT(-93.26)VDLVT(-41.98)T(-33.41)CHIHS(0)S(0)S(0)DDEIDFK 14 3 871.71067 0.059307 0 0 0 0 0 0 0 0 1460 1032 525 525 4353 4951 41295 25399 Mix4_TiO2_Reinj_2_1 4202 41294 25398 Mix4_TiO2_Reinj_1_6 5351 Q5H9R7-5;Q5H9R7;Q5H9R7-2 Q5H9R7-5 Q5H9R7-5 >sp|Q5H9R7-5|PP6R3_HUMAN Isoform 5 of Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3;>sp|Q5H9R7|PP6R3_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens GN=PPP6R3 PE=1 SV=2;>sp|Q5H9R7-2| 0.333276 0 0.279503 0 0.979264 27.54 0 0 0.331898 0 5.25139E-07 107.76 0.333276 0 7.69533E-07 102.95 1 S CHIHSSSDDEIDF CK2 0.117 5.25139E-07 107.76 _NTVDLVTTCHIHpSSSDDEIDFK_ NTVDLVTTCHIHS(0.333)S(0.333)S(0.333)DDEIDFK NT(-93.26)VDLVT(-41.98)T(-33.41)CHIHS(0)S(0)S(0)DDEIDFK 15 3 871.71067 0.059307 0 0 0 0 0 0 0 0 1461 1033 311 311 3771 4256 35689 22055 Mix4_TiO2_Reinj_1_2 4938 35689 22055 Mix4_TiO2_Reinj_1_2 4938 Q5HYI7 Q5HYI7 Q5HYI7 >sp|Q5HYI7|MTX3_HUMAN Metaxin-3 OS=Homo sapiens GN=MTX3 PE=1 SV=2 1 147.543 1 131.998 5.36102E-16 166.8 1 147.543 4.06534E-26 208.78 1 136.397 1.77385E-12 147.58 1 82.4467 3.43085E-12 139.11 1 S NSFQRLSP_____ PKA;Proline-directed 0.042 4.06534E-26 208.78 _LTPAEEENNSFQRLpSP_ LTPAEEENNSFQRLS(1)P LT(-208.78)PAEEENNS(-147.54)FQRLS(147.54)P 15 2 956.42784 0.29192 943490 166120 0 0 470790 0 174610 131960 1462 1033 284 284 3820 4318 36301 22413 Mix4_TiO2_Reinj_1_2 3516 36301 22413 Mix4_TiO2_Reinj_1_2 3516 Q5HYI7 Q5HYI7 Q5HYI7 >sp|Q5HYI7|MTX3_HUMAN Metaxin-3 OS=Homo sapiens GN=MTX3 PE=1 SV=2 1 67.8583 0 0 1 67.8583 0.0157293 67.858 1 S DDNLRQSPQLPPR NEK6;PKA;Proline-directed 0.042 0.0157293 67.858 _M(ox)DDNLRQpSPQLPPR_ MDDNLRQS(1)PQLPPR MDDNLRQS(67.86)PQLPPR 8 3 588.26959 0.22766 46706 0 0 0 46706 0 0 0 1463 1036 118 118 2078 2354 19061 11598 Mix4_TiO2_Reinj_1_5 3949 19061 11598 Mix4_TiO2_Reinj_1_5 3949 Q5JTH9;Q5JTH9-2 Q5JTH9 Q5JTH9 >sp|Q5JTH9|RRP12_HUMAN RRP12-like protein OS=Homo sapiens GN=RRP12 PE=1 SV=2;>sp|Q5JTH9-2|RRP12_HUMAN Isoform 2 of RRP12-like protein OS=Homo sapiens GN=RRP12 0.97868 16.6185 0.97868 16.6185 0.0997286 38.095 1 S RFWESNSAAHKEI 0.0997286 38.095 _FWESNpSAAHK_ FWES(0.021)NS(0.979)AAHK FWES(-16.62)NS(16.62)AAHK 6 2 628.75843 0.040651 68669 0 0 0 68669 0 0 0 1464 1036 1080 1080 2144 2429 19709 12061 Mix4_TiO2_Reinj_1_6 5995 19708 12060 Mix4_TiO2_Reinj_1_6 5986 Q5JTH9;Q5JTH9-2 Q5JTH9 Q5JTH9 >sp|Q5JTH9|RRP12_HUMAN RRP12-like protein OS=Homo sapiens GN=RRP12 PE=1 SV=2;>sp|Q5JTH9-2|RRP12_HUMAN Isoform 2 of RRP12-like protein OS=Homo sapiens GN=RRP12 1 75.6447 1 143.319 6.72199E-39 199.06 1 109.104 2.52228E-17 152.98 1 75.6447 3.8517E-39 205.67 1 68.5789 0.00359663 76.16 0 0 1 S EEILADSEDEEDN CK2;NEK6 0.076 3.8517E-39 205.67 _GDSIEEILADpSEDEEDNEEEER_ GDSIEEILADS(1)EDEEDNEEEER GDS(-75.64)IEEILADS(75.64)EDEEDNEEEER 11 2 1316.5007 0.39064 22668000 4481300 334190 0 17826000 26456 0 0 1465 1037 143 143 3676 4147 34582 21499 Mix4_InSol_TiO2_1 5066 34582 21499 Mix4_InSol_TiO2_1 5066 Q5JTV8;Q5JTV8-2 Q5JTV8 Q5JTV8 >sp|Q5JTV8|TOIP1_HUMAN Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 PE=1 SV=2;>sp|Q5JTV8-2|TOIP1_HUMAN Isoform 2 of Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 0.991556 20.6978 0.991556 20.6978 0.00176832 78.91 0 0 1 S QPPLQPSPVMTRR NEK6;Proline-directed 0.05 0.00176832 78.91 _LQQQHSEQPPLQPpSPVMTR_ LQQQHSEQPPLQPS(0.992)PVMT(0.008)R LQQQHS(-78.91)EQPPLQPS(20.7)PVMT(-20.7)R 14 3 761.03135 -0.42706 140810 0 0 0 0 0 140810 0 1466 1037 315 315 5225 5947 50660 31015 Mix4_TiO2_Reinj_1_4 2629 50660 31015 Mix4_TiO2_Reinj_1_4 2629 Q5JTV8 Q5JTV8 Q5JTV8 >sp|Q5JTV8|TOIP1_HUMAN Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 PE=1 SV=2 0.997715 26.4082 0.988154 19.3803 0.000576079 100.05 0.997715 26.4082 2.45639E-13 180.26 0 0 0 0 1 S SELGNQSPSTSSR GSK3;Proline-directed 0.05 2.45639E-13 180.26 _SELGNQpSPSTSSR_ SELGNQS(0.998)PS(0.002)TSSR S(-158.98)ELGNQS(26.41)PS(-26.41)T(-54.56)S(-70.89)S(-81.91)R 7 2 715.30138 0.50547 391200 8.7167 101680 0 0 289520 0 0 0 1467 1037 242 242 5661 6447 55318 33844 Mix4_TiO2_Reinj_1_4 1048 55318 33844 Mix4_TiO2_Reinj_1_4 1048 Q5JTV8;Q5JTV8-2 Q5JTV8 Q5JTV8 >sp|Q5JTV8|TOIP1_HUMAN Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 PE=1 SV=2;>sp|Q5JTV8-2|TOIP1_HUMAN Isoform 2 of Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 0.996471 24.5854 0.996471 24.5854 0.0702351 46.847 0.481338 5.69626 0.868623 5.6963 0 0 1 S KARSRDSDESGDK CK1;PKA 0.042 0.0702351 46.847 _SRDpSDESGDKTTR_ S(0.003)RDS(0.996)DESGDKTTR S(-24.59)RDS(24.59)DES(-46.85)GDKT(-46.85)T(-46.85)R 4 3 511.87741 0.42301 8278.1 0 0 0 8278.1 0 0 0 1468 1039 117 117 4576 5196 43302 26552 Mix4_TiO2_1_5 5195 43302 26552 Mix4_TiO2_1_5 5195 Q5QJE6 Q5QJE6 Q5QJE6 >sp|Q5QJE6|TDIF2_HUMAN Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens GN=DNTTIP2 PE=1 SV=2 0.997891 27.2225 0.997891 27.2225 0.0020876 91.895 1 S QILIACSPVSSVR GSK3;Proline-directed 0.05 0.0020876 91.895 _QILIACpSPVSSVR_ QILIACS(0.998)PVS(0.002)SVR QILIACS(27.22)PVS(-27.22)S(-36.62)VR 7 2 755.37838 -0.026611 16992 16992 0 0 0 0 0 0 1469 1040 92 92 5291 6024 51371 31449 Mix4_TiO2_1_3 5478 51371 31449 Mix4_TiO2_1_3 5478 Q5QP82;Q5QP82-2 Q5QP82 Q5QP82 >sp|Q5QP82|DCA10_HUMAN DDB1- and CUL4-associated factor 10 OS=Homo sapiens GN=DCAF10 PE=1 SV=1;>sp|Q5QP82-2|DCA10_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 10 OS=Homo sapiens GN=DCAF10 0.999626 34.2724 0.999626 34.2724 0.000281528 80.763 0 0 1 S GEPSPPSPPCRRP CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000281528 80.763 _SGELGLPGAPESSTASAPGEPSPPpSPPCR_ SGELGLPGAPESSTASAPGEPSPPS(1)PPCR S(-80.76)GELGLPGAPES(-80.53)S(-80.53)T(-80.53)AS(-80.76)APGEPS(-34.27)PPS(34.27)PPCR 25 3 957.09518 -0.47465 146740 146740 0 0 0 0 0 0 1470 1041 118 118 4442 5052 42245 26005 Mix4_TiO2_1_5 6055 42245 26005 Mix4_TiO2_1_5 6055 Q5R372-3;Q5R372;Q5R372-4;Q5R372-2 Q5R372-3 Q5R372-3 >sp|Q5R372-3|RBG1L_HUMAN Isoform 3 of Rab GTPase-activating protein 1-like OS=Homo sapiens GN=RABGAP1L;>sp|Q5R372|RBG1L_HUMAN Rab GTPase-activating protein 1-like OS=Homo sapiens GN=RABGAP1L PE=1 SV=1;>sp|Q5R372-4|RBG1L_HUMAN Isoform 4 of Rab GTPase-activa 0.499999 0 0.499999 0 0.0547311 55.841 0 0 1 S ISTPRPSSPGGLP CK1;PKA 0.042 0.0547311 55.841 _PpSSPGGLPEEDSVLFNK_ PS(0.5)S(0.5)PGGLPEEDSVLFNK PS(0)S(0)PGGLPEEDS(-52.87)VLFNK 2 2 926.92186 0.79418 28000 28000 0 0 0 0 0 0 1471 1041 119 119 4442 5052 42245 26005 Mix4_TiO2_1_5 6055 42245 26005 Mix4_TiO2_1_5 6055 Q5R372-3;Q5R372;Q5R372-4;Q5R372-2 Q5R372-3 Q5R372-3 >sp|Q5R372-3|RBG1L_HUMAN Isoform 3 of Rab GTPase-activating protein 1-like OS=Homo sapiens GN=RABGAP1L;>sp|Q5R372|RBG1L_HUMAN Rab GTPase-activating protein 1-like OS=Homo sapiens GN=RABGAP1L PE=1 SV=1;>sp|Q5R372-4|RBG1L_HUMAN Isoform 4 of Rab GTPase-activa 0.499999 0 0.499999 0 0.0547311 55.841 0 0 1 S STPRPSSPGGLPE CAMK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0547311 55.841 _PpSSPGGLPEEDSVLFNK_ PS(0.5)S(0.5)PGGLPEEDSVLFNK PS(0)S(0)PGGLPEEDS(-52.87)VLFNK 3 2 926.92186 0.79418 28000 28000 0 0 0 0 0 0 1472 1042 1176 1176 4538 5154 42962 26373 Mix4_TiO2_Reinj_2_1 2057 42961 26372 Mix4_TiO2_1_1 1852 Q5RGS2;Q5TZJ5;Q5VVP1 Q5RGS2 Q5RGS2 >sp|Q5RGS2|F75A2_HUMAN Protein FAM75A2 OS=Homo sapiens GN=FAM75A2 PE=3 SV=1;>sp|Q5TZJ5|F75A1_HUMAN Protein FAM75A1 OS=Homo sapiens GN=FAM75A1 PE=2 SV=1;>sp|Q5VVP1|F75A6_HUMAN Protein FAM75A6 OS=Homo sapiens GN=FAM75A6 PE=1 SV=1 1 30.7494 1 50.0006 0.0379209 50.001 0 0 0 0 1 30.7494 0.188374 30.749 1 S FFQWIFSKKKSKP GSK3 0.081 0.0379209 50.001 _QFFQWIFpSKK_ QFFQWIFS(1)KK QFFQWIFS(30.75)KK 8 2 719.84959 -0.068603 187230 99711 0 0 0 87517 0 0 1473 1043 454 454 353 402 3300 1982 Mix4_TiO2_1_3 6919 3300 1982 Mix4_TiO2_1_3 6919 Q5SNT2 Q5SNT2 Q5SNT2 >sp|Q5SNT2|TM201_HUMAN Transmembrane protein 201 OS=Homo sapiens GN=TMEM201 PE=1 SV=1 0.999958 43.8213 0.999958 43.8213 0.00939336 74.327 0 0 1 S RLSRALSLGTIPS CAMK2;CHK1;CHK1/2;CK1;PKD 0.003192 0.00939336 74.327 _ALpSLGTIPSLTR_ ALS(1)LGTIPSLTR ALS(43.82)LGT(-43.82)IPS(-74.33)LT(-74.33)R 3 2 654.84979 -0.35089 83580 83580 0 0 0 0 0 0 1474 1043 441 441 5060 5754 48918 29893 Mix4_InSol_TiO2_2 2272 48917 29892 Mix4_InSol_TiO2_1 3212 Q5SNT2 Q5SNT2 Q5SNT2 >sp|Q5SNT2|TM201_HUMAN Transmembrane protein 201 OS=Homo sapiens GN=TMEM201 PE=1 SV=1 0.99688 28.597 0 0 0.974694 19.7422 0.052727 45.098 0.99688 28.597 0.00207952 75.442 0.977051 19.0716 0.0288434 53.006 1 S RSPRRTSPSSLPG CAMK2;PKA;PKA/AKT;Proline-directed 0.00111111 0.00207952 75.442 _RTpSPSSLPGR_ RT(0.001)S(0.997)PS(0.001)S(0.001)LPGR RT(-28.6)S(28.6)PS(-29.97)S(-31.3)LPGR 3 2 569.27424 0.14811 2458600 0 0 0 1872700 0 321870 264030 1475 1045 1708 1708 2109;4877 2389;2390;5546;5547 19369 11786 Mix4_TiO2_2_1 2814 19367 11782 Mix4_TiO2_1_5 4176 Q5SRE5;Q5SRE5-2 Q5SRE5 Q5SRE5 >sp|Q5SRE5|NU188_HUMAN Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 PE=1 SV=1;>sp|Q5SRE5-2|NU188_HUMAN Isoform 2 of Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 0.883495 8.97108 0.849332 8.51501 1.83343E-16 168.99 0.883495 8.97108 0.000240813 96.592 0.531041 1.43036 2.98719E-16 164.62 0.492245 0 0.488991 30.221 0.762797 6.76928 7.97958E-18 175.63 0.627104 2.26789 4.91192E-09 123.98 1 S FRRGAPSSPATGV 1.83343E-16 168.99 _GAPpSSPATGVLPSPQGK_ GAPS(0.883)S(0.112)PAT(0.004)GVLPS(0.001)PQGK GAPS(8.97)S(-8.97)PAT(-23.51)GVLPS(-31.66)PQGK 4 2 815.89545 -0.42472 684400 213760 110470 0 105150 0 137210 117810 1476 1045 1709 1709 2109;4877 2389;2390;5546;5547 19349 11744 Mix4_InSol_TiO2_1 4854 19349 11744 Mix4_InSol_TiO2_1 4854 Q5SRE5;Q5SRE5-2 Q5SRE5 Q5SRE5 >sp|Q5SRE5|NU188_HUMAN Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 PE=1 SV=1;>sp|Q5SRE5-2|NU188_HUMAN Isoform 2 of Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 0.998939 29.8607 0.984653 18.0991 3.29708E-16 163.44 0.390956 -1.55394 0.000240813 96.592 0.984931 18.2904 9.60709E-13 145.77 0.492245 0 0.488991 30.221 0.998939 29.8607 7.97958E-18 175.63 0.905214 9.8001 4.32728E-09 125.6 2 S RRGAPSSPATGVL ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 7.97958E-18 175.63 _GAPSpSPATGVLPpSPQGK_ GAPS(0.001)S(0.999)PATGVLPS(1)PQGK GAPS(-29.86)S(29.86)PAT(-45.28)GVLPS(88.02)PQGK 5 2 855.87862 0.11077 1449700 205870 0 0 818210 0 214850 210790 1477 1045 1717 1717 2109;4877 2389;2390;5546;5547 19361 11767 Mix4_InSol_TiO2_1 5259 19367 11782 Mix4_TiO2_1_5 4176 Q5SRE5;Q5SRE5-2 Q5SRE5 Q5SRE5 >sp|Q5SRE5|NU188_HUMAN Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 PE=1 SV=1;>sp|Q5SRE5-2|NU188_HUMAN Isoform 2 of Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 0.999265 31.3319 0.996722 24.8297 1.83343E-16 168.99 0.977278 20.0098 0.8109 20.01 0.97305 15.5758 2.98719E-16 164.62 0.000467848 -30.2208 0.488991 30.221 0.999265 31.3319 3.2121E-15 138.41 0.999998 56.8334 4.32728E-09 125.6 1 S ATGVLPSPQGKST Proline-directed 0.05 1.83343E-16 168.99 _GAPSSPATGVLPpSPQGK_ GAPSSPAT(0.001)GVLPS(0.999)PQGK GAPS(-106.57)S(-100.23)PAT(-31.33)GVLPS(31.33)PQGK 13 2 815.89545 0.060734 4548600 1629100 0 0 1539100 0 1380400 0 1478 1045 1523 1523 6570 7518 66522 40813 Mix4_InSol_TiO2_1 3031 66529 40820 Mix4_TiO2_Reinj_1_5 2803 Q5SRE5;Q5SRE5-2 Q5SRE5 Q5SRE5 >sp|Q5SRE5|NU188_HUMAN Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 PE=1 SV=1;>sp|Q5SRE5-2|NU188_HUMAN Isoform 2 of Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 0.999981 47.3277 0.999672 35.7147 0.000217791 97.204 0 0 0.980509 17.2413 1.77301E-05 98.77 0.999981 47.3277 0.0170621 67.217 0.997211 30.2592 0.0415032 57.751 1 S RVQRPPSAASAAP CAMK2;CHK1;PKD 0.020748 1.77301E-05 98.77 _VQRPPpSAASAAPSSSK_ VQRPPS(1)AASAAPSSSK VQRPPS(47.33)AAS(-47.33)AAPS(-67.22)S(-67.22)S(-67.22)K 6 3 540.92956 0.76618 1364900 27.838 277700 0 0 691090 0 194850 201210 1479 1047 14 14 332 375 3057 1859 Mix4_TiO2_Reinj_1_2 3977 3057 1859 Mix4_TiO2_Reinj_1_2 3977 Q5SW96 Q5SW96 Q5SW96 >sp|Q5SW96|ARH_HUMAN Low density lipoprotein receptor adapter protein 1 OS=Homo sapiens GN=LDLRAP1 PE=1 SV=3 0.99601 23.9734 0.622638 2.17477 0.74752 2.1748 0.99601 23.9734 0.0456267 47.449 0 0 0 0 1 S GRALIRSPSLAKQ NEK6;Proline-directed 0.05 0.0456267 47.449 _ALIRpSPSLAK_ ALIRS(0.996)PS(0.004)LAK ALIRS(23.97)PS(-23.97)LAK 5 2 568.31538 0.088147 71278 16643 0 0 54635 0 0 0 1480 1048 960 960 5001 5687 48273 29486 Mix4_TiO2_Reinj_1_5 3428 48273 29486 Mix4_TiO2_Reinj_1_5 3428 Q5T1M5;Q5T1M5-2 Q5T1M5 Q5T1M5 >sp|Q5T1M5|FKB15_HUMAN FK506-binding protein 15 OS=Homo sapiens GN=FKBP15 PE=1 SV=2;>sp|Q5T1M5-2|FKB15_HUMAN Isoform 2 of FK506-binding protein 15 OS=Homo sapiens GN=FKBP15 0.604489 3.88626 0 0 0.604489 3.88626 5.5227E-07 107.2 1 S RPSQEQSASASSG CK1;GSK3 0.081 5.5227E-07 107.2 _RPSQEQpSASASSGQPQAPLNR_ RPS(0.136)QEQS(0.604)AS(0.247)AS(0.012)SGQPQAPLNR RPS(-6.47)QEQS(3.89)AS(-3.89)AS(-16.97)S(-47.5)GQPQAPLNR 7 3 759.35203 0.69617 83822 0 0 0 83822 0 0 0 1481 1049 619 619 62 74 612 401 Mix4_TiO2_1_1 3906 614 406 Mix4_TiO2_Reinj_1_1 4279 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.87167 8.32026 0.87167 8.32026 9.70861E-06 99.698 0 0 0.5 0 2.01753E-09 131.87 0 0 0.544119 0.768418 0.0017134 82.486 0.5 0 0.0322146 59.14 1 S PPPPLESSPRVKS 2.01753E-09 131.87 _AAPPPPPPPPPLEpSSPR_ AAPPPPPPPPPLES(0.872)S(0.128)PR AAPPPPPPPPPLES(8.32)S(-8.32)PR 14 2 892.44257 0.41405 1958800 201090 0 0 835780 0 465430 456500 1482 1049 620 620 62 74 611 397 Mix4_TiO2_1_1 3920 614 406 Mix4_TiO2_Reinj_1_1 4279 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.9121 10.1605 0.9121 10.1605 9.70861E-06 99.698 0 0 0.883019 8.77855 2.01753E-09 131.87 0 0 0.873542 8.39336 0.0017134 82.486 0.863181 7.99954 0.0322146 59.14 1 S PPPLESSPRVKSP CDK1;NEK6;Polo box;Proline-directed 0.00405 2.01753E-09 131.87 _AAPPPPPPPPPLESpSPR_ AAPPPPPPPPPLES(0.088)S(0.912)PR AAPPPPPPPPPLES(-10.16)S(10.16)PR 15 3 595.29747 0.21511 4448400 317510 0 0 1853500 0 1173000 1104500 1483 1049 178 178 1633;6084 1833;6939 60108 36422 Mix4_TiO2_Reinj_1_1 5355 60108 36422 Mix4_TiO2_Reinj_1_1 5355 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.999977 46.3967 2.7169E-05 -45.6591 9.81764E-07 108.3 0 0 0.999977 46.3967 1.26644E-10 126.38 0 0 0.0455698 -13.2101 0.182987 41.744 1 S DQKELASPVSPEL Proline-directed 0.05 1.26644E-10 126.38 _TLSDVEDQKELApSPVSPELR_ TLSDVEDQKELAS(1)PVSPELR T(-118.23)LS(-116.13)DVEDQKELAS(46.4)PVS(-46.4)PELR 13 3 765.03682 0.17039 567330 0 0 0 567330 0 0 0 1484 1049 181 181 1633;6084 1833;6939 14984 9058 Mix4_TiO2_Reinj_1_1 4985 60108 36422 Mix4_TiO2_Reinj_1_1 5355 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 1 63.5632 0.999973 45.6591 9.81764E-07 108.3 0 0 1 63.5632 1.26644E-10 126.38 0 0 0.954302 13.2101 0.182987 41.744 1 S ELASPVSPELRQK CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.26644E-10 126.38 _ELASPVpSPELR_ ELASPVS(1)PELR ELAS(-63.56)PVS(63.56)PELR 7 2 639.31049 -0.068771 274030 131030 0 0 72952 0 0 70048 1485 1049 1760 1760 2560;2561 2908;2910;2911 23997 14879 Mix4_InSol_TiO2_1 1451 23996 14878 Mix4_InSol_TiO2_1 1224 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.911646 14.9072 0 0 0.130597 -7.68412 0.271746 25.851 0 0 0.911646 14.9072 0.00317244 91.53 0.856314 8.81613 0.00611111 80.984 1 S SLVRHASTSSPAD CAMK2;CHK1;CHK1/2;PKD 0.003192 0.00317244 91.53 _HApSTSSPADKAK_ HAS(0.912)T(0.029)S(0.029)S(0.029)PADKAK HAS(14.91)T(-14.91)S(-14.91)S(-14.91)PADKAK 3 2 640.28755 0.24118 426610 71.281 0 0 0 0 0 370310 56299 1486 1049 1762 1762 2560;2561 2908;2910;2911 23999 14881 Mix4_InSol_TiO2_2 1015 23996 14878 Mix4_InSol_TiO2_1 1224 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.79578 10.6782 0 0 0.0996098 -8.86042 0.271746 25.851 0 0 0.79578 10.6782 0.00317244 91.53 0.891824 9.36946 0.301903 23.408 1 S VRHASTSSPADKA 0.00317244 91.53 _HASTpSSPADKAK_ HAS(0.068)T(0.068)S(0.796)S(0.068)PADKAK HAS(-10.68)T(-10.68)S(10.68)S(-10.68)PADKAK 5 2 640.28755 0.5266 484810 81.005 0 0 0 0 0 20626 464180 1487 1049 1763 1763 2560;2561 2908;2910;2911 23996 14878 Mix4_InSol_TiO2_1 1224 23996 14878 Mix4_InSol_TiO2_1 1224 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.921556 10.868 0 0 0.00359087 -23.2914 0.271746 25.851 0 0 0.921556 10.868 0.00317244 91.53 0.314649 -3.37702 0.00611111 80.984 1 S RHASTSSPADKAK CK1;CK2;Polo box;Proline-directed 0.00405 0.00317244 91.53 _HASTSpSPADKAK_ HAST(0.003)S(0.075)S(0.922)PADKAK HAS(-59.52)T(-24.9)S(-10.87)S(10.87)PADKAK 6 2 640.28755 0.18038 408420 68.242 0 0 0 0 0 408420 0 1488 1049 2718 2718 2681;4911 3054;5584 25180 15550 Mix4_InSol_TiO2_2 3001 25179 15549 Mix4_InSol_TiO2_1 4049 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.946117 12.4455 0.763045 5.07885 0.00630512 65.408 0 0 0.934234 11.5247 0.00781989 61.621 0 0 0.946117 12.4455 0.00302777 73.6 0.932975 11.4382 0.0381842 50.795 1 S RHVTLPSSPRSNT GSK3 0.081 0.00302777 73.6 _HVTLPpSSPR_ HVTLPS(0.946)S(0.054)PR HVT(-51.6)LPS(12.45)S(-12.45)PR 6 2 537.26061 -0.26094 10778000 1343500 0 0 6471800 0 1592200 1370800 1489 1049 2719 2719 2681;4911 3054;5584 47112 28799 Mix4_InSol_TiO2_1 3857 25179 15549 Mix4_InSol_TiO2_1 4049 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.826757 6.8128 0.386031 -2.01516 0.00630512 65.408 0 0 0.39936 -1.74051 0.00781989 61.621 0 0 0.826757 6.8128 0.00302777 73.6 0.403551 -1.69619 0.0381842 50.795 1 S HVTLPSSPRSNTP CDK1;CK1;ERK/MAPK;NEK6;Polo box;Proline-directed;WW GroupIV 0.0023175 0.00302777 73.6 _RHVTLPSpSPR_ RHVT(0.001)LPS(0.172)S(0.827)PR RHVT(-29.1)LPS(-6.81)S(6.81)PR 8 3 410.5432 0.053482 67424 0 0 0 0 0 67424 0 1490 1049 362 362 6006 6846 59285 36026 Mix4_TiO2_Reinj_1_1 4803 59285 36026 Mix4_TiO2_Reinj_1_1 4803 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.551133 1.64916 0.545253 1.51748 8.00277E-24 165.69 0.192624 0 1.10746 22.641 0.551133 1.64916 2.88338E-32 181.34 0 0 0.507632 0.989352 7.97195E-05 96.097 0.543737 1.55425 5.59385E-24 168.78 1 S QQVRTGSTSSKED CAMK2;PKA/AKT 0.00111111 2.88338E-32 181.34 _TGpSTSSKEDDYESDAATIVQK_ T(0.377)GS(0.551)T(0.063)S(0.008)S(0.001)KEDDYESDAATIVQK T(-1.65)GS(1.65)T(-9.39)S(-18.63)S(-27.64)KEDDY(-149.52)ES(-151.52)DAAT(-181.34)IVQK 3 2 1156.4943 0.4532 1823000 93646 0 0 1062500 0 48783 618150 1491 1049 364 364 6006 6846 59280 36021 Mix4_TiO2_1_1 4242 59285 36026 Mix4_TiO2_Reinj_1_1 4803 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.24675 0 0.24675 0 8.00277E-24 165.69 0.192624 0 1.10746 22.641 0.00770834 -18.402 2.88338E-32 181.34 0 0 0.159231 -0.501166 7.97195E-05 96.097 0.205081 0 5.59385E-24 168.78 1 S VRTGSTSSKEDDY CK1;CK2 0.117 2.88338E-32 181.34 _TGSTpSSKEDDYESDAATIVQK_ T(0.138)GS(0.184)T(0.184)S(0.247)S(0.247)KEDDYESDAATIVQK T(-2.52)GS(-1.27)T(-1.27)S(0)S(0)KEDDY(-113.79)ES(-107.53)DAAT(-155.67)IVQK 5 2 1156.4943 0.94763 0 0 0 0 0 0 0 0 1492 1049 365 365 6006 6846 59280 36021 Mix4_TiO2_1_1 4242 59285 36026 Mix4_TiO2_Reinj_1_1 4803 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.24675 0 0.24675 0 8.00277E-24 165.69 0.192624 0 1.10746 22.641 0.00770834 -18.402 2.88338E-32 181.34 0 0 0.178708 0 7.97195E-05 96.097 0.205081 0 5.59385E-24 168.78 1 S RTGSTSSKEDDYE CK1;CK2 0.081 2.88338E-32 181.34 _TGSTpSSKEDDYESDAATIVQK_ T(0.138)GS(0.184)T(0.184)S(0.247)S(0.247)KEDDYESDAATIVQK T(-2.52)GS(-1.27)T(-1.27)S(0)S(0)KEDDY(-113.79)ES(-107.53)DAAT(-155.67)IVQK 6 2 1156.4943 0.94763 0 0 0 0 0 0 0 0 1493 1049 2885 2885 6222 7108 61631 37354 Mix4_TiO2_Reinj_1_1 3775 61631 37354 Mix4_TiO2_Reinj_1_1 3775 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.545825 0.798448 0.481424 0 0.0411702 65.001 0 0 0.545825 0.798448 3.3147E-08 113.2 0 0 0 0 1 S GSTLRTSPADHGG CK1;CK2;NEK6;PKA;Proline-directed 0.042 3.3147E-08 113.2 _TpSPADHGGSVGSESGGSAVDSVAGEHSVSGR_ T(0.454)S(0.546)PADHGGSVGSESGGSAVDSVAGEHSVSGR T(-0.8)S(0.8)PADHGGS(-46.15)VGS(-54.76)ES(-61.71)GGS(-72.53)AVDS(-103.79)VAGEHS(-113.2)VS(-113.2)GR 2 3 974.08288 -0.019295 1889300 4.8971 0 0 0 1889300 0 0 0 1494 1049 625 625 6453 7382 65153 39968 Mix4_InSol_Tio2_Reinj_1 1852 65153 39968 Mix4_InSol_Tio2_Reinj_1 1852 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.999753 36.0786 0.949369 12.7302 0.0158524 62.661 0.999753 36.0786 0.00802196 76.804 1 S SSPRVKSPSKQAP CAMK2;CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 0.00802196 76.804 _VKpSPSKQAPGEK_ VKS(1)PSKQAPGEK VKS(36.08)PS(-36.08)KQAPGEK 3 3 445.89379 -0.01223 787250 0 0 0 0 0 352050 435200 1495 1049 627 627 6453 7382 65150 39964 Mix4_InSol_TiO2_1 1763 65153 39968 Mix4_InSol_Tio2_Reinj_1 1852 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.999553 33.4987 0.999553 33.4987 0.0158524 62.661 0.994799 22.8165 0.00802196 76.804 1 S PRVKSPSKQAPGE 0.00802196 76.804 _VKSPpSKQAPGEK_ VKSPS(1)KQAPGEK VKS(-33.5)PS(33.5)KQAPGEK 5 2 668.33704 -0.41186 1481100 0 0 0 0 0 653280 827790 1496 1054 184 184 190 220 1993 1319 Mix4_TiO2_Reinj_1_4 4288 1993 1319 Mix4_TiO2_Reinj_1_4 4288 Q5T8D3-3;Q5T8D3-2;Q5T8D3-4;Q5T8D3 Q5T8D3-3 Q5T8D3-3 >sp|Q5T8D3-3|ACBD5_HUMAN Isoform 3 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-2|ACBD5_HUMAN Isoform 2 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-4|ACBD5_HUMAN Isoform 4 of Ac 0.431342 0 0.149605 -6.56603 2.32564E-11 135.37 0.431342 0 3.86148E-27 191.85 2 S VNGKAESSDSGAE 3.86148E-27 191.85 _AEpSSDSGAEpSEEEEAQEEVK_ AES(0.431)S(0.431)DS(0.137)GAES(1)EEEEAQEEVK AES(0)S(0)DS(-4.97)GAES(96.59)EEEEAQEEVK 3 2 1150.4042 0.40699 0 0 0 0 0 0 0 0 1497 1054 185 185 190 220 1993 1319 Mix4_TiO2_Reinj_1_4 4288 1993 1319 Mix4_TiO2_Reinj_1_4 4288 Q5T8D3-3;Q5T8D3-2;Q5T8D3-4;Q5T8D3 Q5T8D3-3 Q5T8D3-3 >sp|Q5T8D3-3|ACBD5_HUMAN Isoform 3 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-2|ACBD5_HUMAN Isoform 2 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-4|ACBD5_HUMAN Isoform 4 of Ac 0.431342 0 0.171897 -5.96281 2.32564E-11 135.37 0.431342 0 3.86148E-27 191.85 2 S NGKAESSDSGAES 3.86148E-27 191.85 _AEpSSDSGAEpSEEEEAQEEVK_ AES(0.431)S(0.431)DS(0.137)GAES(1)EEEEAQEEVK AES(0)S(0)DS(-4.97)GAES(96.59)EEEEAQEEVK 4 2 1150.4042 0.40699 0 0 0 0 0 0 0 0 1498 1054 187 187 190 220 1992 1318 Mix4_TiO2_Reinj_1_3 4350 1993 1319 Mix4_TiO2_Reinj_1_4 4288 Q5T8D3-3;Q5T8D3-2;Q5T8D3-4;Q5T8D3 Q5T8D3-3 Q5T8D3-3 >sp|Q5T8D3-3|ACBD5_HUMAN Isoform 3 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-2|ACBD5_HUMAN Isoform 2 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-4|ACBD5_HUMAN Isoform 4 of Ac 0.929626 14.2193 0.678498 5.96281 2.32564E-11 135.37 0.929626 14.2193 3.86148E-27 191.85 2 S KAESSDSGAESEE CK1;CK2;F box bTrCP;GSK3 0.000624338 3.86148E-27 191.85 _AESSDpSGAEpSEEEEAQEEVK_ AES(0.035)S(0.035)DS(0.93)GAES(1)EEEEAQEEVK AES(-14.22)S(-14.22)DS(14.22)GAES(76.71)EEEEAQEEVK 6 2 1150.4042 0.63861 1076500 251940 0 0 824560 0 0 0 1499 1054 191 191 190 220 1993 1319 Mix4_TiO2_Reinj_1_4 4288 1993 1319 Mix4_TiO2_Reinj_1_4 4288 Q5T8D3-3;Q5T8D3-2;Q5T8D3-4;Q5T8D3 Q5T8D3-3 Q5T8D3-3 >sp|Q5T8D3-3|ACBD5_HUMAN Isoform 3 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-2|ACBD5_HUMAN Isoform 2 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-4|ACBD5_HUMAN Isoform 4 of Ac 1 96.594 1 80.4751 2.32564E-11 135.37 1 96.594 3.86148E-27 191.85 2 S SDSGAESEEEEAQ CK1;CK2;F box bTrCP 0.000624338 3.86148E-27 191.85 _AEpSSDSGAEpSEEEEAQEEVK_ AES(0.431)S(0.431)DS(0.137)GAES(1)EEEEAQEEVK AES(0)S(0)DS(-4.97)GAES(96.59)EEEEAQEEVK 10 2 1150.4042 0.40699 1535000 251940 0 0 1283000 0 0 0 1500 1054 171 171 5690 6480 55711 34143 Mix4_TiO2_1_3 6146 55710 34142 Mix4_TiO2_1_3 6133 Q5T8D3-3;Q5T8D3-2;Q5T8D3-4 Q5T8D3-3 Q5T8D3-3 >sp|Q5T8D3-3|ACBD5_HUMAN Isoform 3 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-2|ACBD5_HUMAN Isoform 2 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-4|ACBD5_HUMAN Isoform 4 of Ac 0.606515 1.8801 0.606515 1.8801 8.46769E-39 218.58 0.142159 -7.80552 2.73904E-21 165.64 0.170674 -6.83772 0.0316233 58.889 0.457112 0 7.95436E-32 207.56 1 S LGNVLTSTPNAKT 8.46769E-39 218.58 _SSDITSDLGNVLTpSTPNAK_ SSDITSDLGNVLTS(0.607)T(0.393)PNAK S(-153.91)S(-153.91)DIT(-153.91)S(-138.76)DLGNVLT(-38.38)S(1.88)T(-1.88)PNAK 14 3 667.31217 1.1671 105210 1.935 105210 0 0 0 0 0 0 1501 1056 99 99 6425 7349 64884 39800 Mix4_TiO2_Reinj_1_5 3661 64884 39800 Mix4_TiO2_Reinj_1_5 3661 Q5TAQ9;Q5TAQ9-2 Q5TAQ9 Q5TAQ9 >sp|Q5TAQ9|DCAF8_HUMAN DDB1- and CUL4-associated factor 8 OS=Homo sapiens GN=DCAF8 PE=1 SV=1;>sp|Q5TAQ9-2|DCAF8_HUMAN Isoform 2 of DDB1- and CUL4-associated factor 8 OS=Homo sapiens GN=DCAF8 1 110.419 0 0 1 110.419 3.89273E-07 110.42 1 S NRVHDRSEEEEEE CK2 0.117 3.89273E-07 110.42 _VHDRpSEEEEEEEEEEEEEQPR_ VHDRS(1)EEEEEEEEEEEEEQPR VHDRS(110.42)EEEEEEEEEEEEEQPR 5 3 918.01743 -0.15548 337950 0 0 0 337950 0 0 0 1502 1059 614 614 2899 3302 27751 17290 Mix4_TiO2_1_5 7443 27752 17291 Mix4_TiO2_Reinj_1_5 8206 Q5TCX8;Q5TCX8-3 Q5TCX8 Q5TCX8 >sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase MLK4 OS=Homo sapiens GN=MLK4 PE=1 SV=1;>sp|Q5TCX8-3|M3KL4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase MLK4 OS=Homo sapiens GN=MLK4 0.998771 29.5807 0.998771 29.5807 0.115312 47.053 0.798297 5.97472 0.0753888 52.86 1 S ERIRPLSDGNSPW CAMK2;GSK3;PKA/AKT 0.001764 0.0753888 52.86 _IRPLpSDGNSPWSTILIK_ IRPLS(0.999)DGNS(0.001)PWSTILIK IRPLS(29.58)DGNS(-29.58)PWS(-43.29)T(-40.87)ILIK 5 2 989.01389 0.84904 154320 44369 0 0 109960 0 0 0 1503 1059 528 528 2931 3335 27993 17409 Mix4_TiO2_Reinj_1_5 4399 27993 17409 Mix4_TiO2_Reinj_1_5 4399 Q5TCX8;Q5TCX8-2 Q5TCX8 Q5TCX8 >sp|Q5TCX8|M3KL4_HUMAN Mitogen-activated protein kinase kinase kinase MLK4 OS=Homo sapiens GN=MLK4 PE=1 SV=1;>sp|Q5TCX8-2|M3KL4_HUMAN Isoform MLK4alpha of Mitogen-activated protein kinase kinase kinase MLK4 OS=Homo sapiens GN=MLK4 1 77.0003 0 0 1 77.0003 0.00407318 77 1 S KITVQASPNLDKR CK1;Proline-directed 0.05 0.00407318 77 _ITVQApSPNLDK_ ITVQAS(1)PNLDK IT(-77)VQAS(77)PNLDK 6 2 633.31049 0.55926 143180 0 0 0 143180 0 0 0 1504 1061 1991 1991 230 264 2269 1463 Mix4_TiO2_Reinj_1_1 5534 2269 1463 Mix4_TiO2_Reinj_1_1 5534 Q5TH69 Q5TH69 Q5TH69 >sp|Q5TH69|BIG3_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 3 OS=Homo sapiens GN=ARFGEF3 PE=1 SV=3 1 44.5674 1 20.6349 0.0838304 43.153 1 44.5674 0.0786236 44.567 0 0 0 0 0 0 1 S DLLLPPSPKVEKK CDK1;ERK/MAPK;NEK6;Proline-directed;WW GroupIV 0.0023175 0.0786236 44.567 _AGGGDLLLPPpSPK_ AGGGDLLLPPS(1)PK AGGGDLLLPPS(44.57)PK 11 2 651.32869 0.39716 235230 64787 0 0 170440 0 0 0 1505 1061 2095 2095 5331 6072 51787 31702 Mix4_TiO2_Reinj_1_1 3984 51787 31702 Mix4_TiO2_Reinj_1_1 3984 Q5TH69 Q5TH69 Q5TH69 >sp|Q5TH69|BIG3_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 3 OS=Homo sapiens GN=ARFGEF3 PE=1 SV=3 0.86621 8.11564 0 0 0.86621 8.11564 0.0621761 49.037 1 S QDKRPRSGSTGSS CAMK2;PKA 0.003024 0.0621761 49.037 _pSGSTGSSLSVSVR_ S(0.866)GS(0.134)TGSSLSVSVR S(8.12)GS(-8.12)T(-40.99)GS(-49.04)S(-49.04)LS(-49.04)VS(-49.04)VR 1 2 652.29811 0.43489 192890 0 0 0 192890 0 0 0 1506 1063 2243 2243 5828 6646 57471 34986 Mix4_TiO2_Reinj_1_5 1487 57470 34985 Mix4_TiO2_Reinj_1_1 1169 Q5UIP0;Q5UIP0-2 Q5UIP0 Q5UIP0 >sp|Q5UIP0|RIF1_HUMAN Telomere-associated protein RIF1 OS=Homo sapiens GN=RIF1 PE=1 SV=2;>sp|Q5UIP0-2|RIF1_HUMAN Isoform 2 of Telomere-associated protein RIF1 OS=Homo sapiens GN=RIF1 0.731952 11.3524 0 0 0 0 0.731952 11.3524 0.0737945 41.578 0.313417 3.584 0.68605 3.584 0 0 1 S GKSVKTSPTTQSK CK1;Proline-directed 0.05 0.0737945 41.578 _SVKTpSPTTQSK_ S(0.054)VKT(0.054)S(0.732)PT(0.054)T(0.054)QS(0.054)K S(-11.35)VKT(-11.35)S(11.35)PT(-11.35)T(-11.35)QS(-11.35)K 5 2 622.30012 -0.59933 17378 0 0 0 17378 0 0 0 1507 1065 335 335 73 87 845 566 Mix4_TiO2_1_5 4639 845 566 Mix4_TiO2_1_5 4639 Q5VSL9;Q5VSL9-2;Q5VSL9-3 Q5VSL9 Q5VSL9 >sp|Q5VSL9|FA40A_HUMAN Protein FAM40A OS=Homo sapiens GN=FAM40A PE=1 SV=1;>sp|Q5VSL9-2|FA40A_HUMAN Isoform 2 of Protein FAM40A OS=Homo sapiens GN=FAM40A;>sp|Q5VSL9-3|FA40A_HUMAN Isoform 3 of Protein FAM40A OS=Homo sapiens GN=FAM40A 1 84.5975 1 84.5975 1.2744E-33 218.91 0 0 1 72.0641 1.04575E-20 190.42 0.999999 61.6016 3.02064E-06 112.4 0.999908 40.3842 0.0147394 68.645 1 S RNMRAASPPASAS CAMK2;GSK3;Proline-directed 0.042 1.2744E-33 218.91 _AApSPPASASDLIEQQQK_ AAS(1)PPASASDLIEQQQK AAS(84.6)PPAS(-84.6)AS(-128.36)DLIEQQQK 3 2 910.92494 0.49788 1250600 390390 0 0 682880 0 96272 81105 1508 1065 339 339 73 87 848 569 Mix4_TiO2_Reinj_1_5 5342 845 566 Mix4_TiO2_1_5 4639 Q5VSL9;Q5VSL9-2;Q5VSL9-3 Q5VSL9 Q5VSL9 >sp|Q5VSL9|FA40A_HUMAN Protein FAM40A OS=Homo sapiens GN=FAM40A PE=1 SV=1;>sp|Q5VSL9-2|FA40A_HUMAN Isoform 2 of Protein FAM40A OS=Homo sapiens GN=FAM40A;>sp|Q5VSL9-3|FA40A_HUMAN Isoform 3 of Protein FAM40A OS=Homo sapiens GN=FAM40A 0.587399 2.50091 1.15311E-08 -79.3813 1.2744E-33 218.91 0 0 0.587399 2.50091 1.04575E-20 190.42 6.9157E-07 -61.6016 3.02064E-06 112.4 9.15256E-05 -40.3842 0.0147394 68.645 1 S AASPPASASDLIE CK1;CK2 0.117 1.2744E-33 218.91 _AASPPApSASDLIEQQQK_ AAS(0.33)PPAS(0.587)AS(0.082)DLIEQQQK AAS(-2.5)PPAS(2.5)AS(-8.53)DLIEQQQK 7 3 607.61905 -0.81822 141070 0 0 0 141070 0 0 0 1509 1066 2101 2101 2864 3262 27298 17059 Mix4_TiO2_Reinj_1_1 5211 27298 17059 Mix4_TiO2_Reinj_1_1 5211 Q5VUA4 Q5VUA4 Q5VUA4 >sp|Q5VUA4|ZN318_HUMAN Zinc finger protein 318 OS=Homo sapiens GN=ZNF318 PE=1 SV=2 1 46.3664 0 0 1 46.3664 0.112014 46.366 1 S RSVRIPSPNILKT CAMK2;Proline-directed 0.042 0.112014 46.366 _IPpSPNILK_ IPS(1)PNILK IPS(46.37)PNILK 3 2 481.25954 -0.50004 28784 0 0 0 28784 0 0 0 1510 1067 833 833 4050 4616 38316 23506 Mix4_TiO2_1_5 5731 38316 23506 Mix4_TiO2_1_5 5731 Q5VYK3 Q5VYK3 Q5VYK3 >sp|Q5VYK3|ECM29_HUMAN Proteasome-associated protein ECM29 homolog OS=Homo sapiens GN=ECM29 PE=1 SV=2 0.786588 6.26088 0.786588 6.26088 0.0458665 56.468 0 0 1 S PIPSEGSGFTKLH CK1 0.081 0.0458665 56.468 _NGPLPIPSEGpSGFTK_ NGPLPIPS(0.027)EGS(0.787)GFT(0.186)K NGPLPIPS(-14.59)EGS(6.26)GFT(-6.26)K 11 2 790.87145 0.20646 22866 22866 0 0 0 0 0 0 1511 1068 674 674 4421 5030 42092 25931 Mix4_TiO2_1_3 6182 42093 25933 Mix4_TiO2_1_5 6051 Q5XPI4-2;Q5XPI4 Q5XPI4-2 Q5XPI4-2 >sp|Q5XPI4-2|RN123_HUMAN Isoform 2 of E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens GN=RNF123;>sp|Q5XPI4|RN123_HUMAN E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens GN=RNF123 PE=1 SV=1 0.525705 1.37122 0.525705 1.37122 0.00239308 86.828 0.101507 -9.12905 0.00805056 67.215 0.0506624 -12.1258 0.0112203 60.136 0 0 0 0 0 0 1 S PRPGWLSSPTLGR 0.00239308 86.828 _PGWLpSSPTLGR_ PGWLS(0.526)S(0.383)PT(0.091)LGR PGWLS(1.37)S(-1.37)PT(-7.62)LGR 5 2 625.8001 -0.1618 40977 40977 0 0 0 0 0 0 1512 1068 675 675 4421 5030 42095 25937 Mix4_TiO2_Reinj_1_1 6385 42093 25933 Mix4_TiO2_1_5 6051 Q5XPI4-2;Q5XPI4 Q5XPI4-2 Q5XPI4-2 >sp|Q5XPI4-2|RN123_HUMAN Isoform 2 of E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens GN=RNF123;>sp|Q5XPI4|RN123_HUMAN E3 ubiquitin-protein ligase RNF123 OS=Homo sapiens GN=RNF123 PE=1 SV=1 0.972906 18.5622 0.943086 15.2036 0.00239308 86.828 0.830619 9.12905 0.00805056 67.215 0.972906 18.5622 0.0112203 60.136 0 0 0 0 0 0 1 S RPGWLSSPTLGRA Polo box;Proline-directed 0.00405 0.00239308 86.828 _PGWLSpSPTLGR_ PGWLS(0.014)S(0.973)PT(0.014)LGR PGWLS(-18.56)S(18.56)PT(-18.56)LGR 6 2 625.8001 -0.12732 3818400 969680 157040 0 2691600 0 0 0 1513 1069 18 18 6304 7204 63057 38404 Mix4_TiO2_1_4 3846 63057 38404 Mix4_TiO2_1_4 3846 Q5XUX1;Q5XUX1-2;Q5XUX1-3 Q5XUX1 Q5XUX1 >sp|Q5XUX1|FBXW9_HUMAN F-box/WD repeat-containing protein 9 OS=Homo sapiens GN=FBXW9 PE=1 SV=2;>sp|Q5XUX1-2|FBXW9_HUMAN Isoform 2 of F-box/WD repeat-containing protein 9 OS=Homo sapiens GN=FBXW9;>sp|Q5XUX1-3|FBXW9_HUMAN Isoform 3 of F-box/WD repeat-contain 0.999203 32.8787 0.999203 32.8787 9.41265E-16 147.84 0.959245 13.7357 1.22792E-15 145.15 0 0 0 0 1 S RTWDDDSDPESET CK2;GSK3 0.081 9.41265E-16 147.84 _TWDDDpSDPESETDPDAQAK_ T(0.001)WDDDS(0.999)DPESETDPDAQAK T(-32.88)WDDDS(32.88)DPES(-35.52)ET(-59.96)DPDAQAK 6 2 1101.4052 0.14511 454010 137690 0 0 316320 0 0 0 1514 1070 346 346 817 926 7728 4576 Mix4_TiO2_1_1 3847 7728 4576 Mix4_TiO2_1_1 3847 Q63HN8 Q63HN8 Q63HN8 >sp|Q63HN8|RN213_HUMAN RING finger protein 213 OS=Homo sapiens GN=RNF213 PE=1 SV=2 0.998976 30.4251 0.998976 30.4251 0.000343559 96.22 0 0 0 0 1 S LHTSDQSPGKHMV CDK1;CDK2;CK1;Proline-directed 0.0057 0.000343559 96.22 _DFATPSLHTSDQpSPGK_ DFATPS(0.001)LHTSDQS(0.999)PGK DFAT(-71.74)PS(-30.43)LHT(-39.81)S(-48.56)DQS(30.43)PGK 13 2 884.38291 0.71922 101470 101470 0 0 0 0 0 0 1515 1071 845 845 245 282 2466 1560 Mix4_TiO2_Reinj_1_5 4461 2466 1560 Mix4_TiO2_Reinj_1_5 4461 Q63HR2-4;Q63HR2;Q63HR2-6;Q63HR2-3;Q63HR2-5 Q63HR2-4 Q63HR2-4 >sp|Q63HR2-4|TENC1_HUMAN Isoform 4 of Tensin-like C1 domain-containing phosphatase OS=Homo sapiens GN=TENC1;>sp|Q63HR2|TENC1_HUMAN Tensin-like C1 domain-containing phosphatase OS=Homo sapiens GN=TENC1 PE=1 SV=2;>sp|Q63HR2-6|TENC1_HUMAN Isoform 6 of Tensin- 0.976241 16.8936 0 0 0.976241 16.8936 0.0154034 68.594 0 0 0.966706 15.5609 0.445896 28.265 1 S GSISPGSPPYPQS CK1;ERK/MAPK;Proline-directed 0.0025 0.0154034 68.594 _AGSISPGpSPPYPQSR_ AGS(0.001)IS(0.003)PGS(0.976)PPY(0.02)PQSR AGS(-32.32)IS(-24.82)PGS(16.89)PPY(-16.89)PQS(-53.32)R 8 2 790.85887 0.58459 162800 0 0 0 133040 0 0 29758 1516 1074 419 419 548;2975 624;3384 28340 17599 Mix4_TiO2_1_5 4227 28337 17595 Mix4_InSol_TiO2_1 4993 Q66K14;Q66K14-2 Q66K14 Q66K14 >sp|Q66K14|TBC9B_HUMAN TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3;>sp|Q66K14-2|TBC9B_HUMAN Isoform 2 of TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B 0.29984 0 0.29984 0 1.16142E-12 123.81 0 0 0.143023 -5.7076 1.38233E-12 123.36 1.12952E-10 -95.6778 5.32338E-19 138.63 0.00345703 -22.0777 9.42168E-05 94.319 1 S VDPSTESSPAPQE CK1 0.081 5.32338E-19 138.63 _KASVVDPSTEpSSPAPQEGSEQPASPASPLSSR_ KASVVDPS(0.062)T(0.062)ES(0.3)S(0.3)PAPQEGS(0.196)EQPAS(0.056)PAS(0.015)PLS(0.004)S(0.004)R KAS(-33.24)VVDPS(-6.83)T(-6.83)ES(0)S(0)PAPQEGS(-1.85)EQPAS(-7.26)PAS(-12.96)PLS(-18.48)S(-18.48)R 11 3 1087.5033 -1.1399 0 0 0 0 0 0 0 0 0 1517 1074 420 420 548;2975 624;3384 28340 17599 Mix4_TiO2_1_5 4227 28337 17595 Mix4_InSol_TiO2_1 4993 Q66K14;Q66K14-2 Q66K14 Q66K14 >sp|Q66K14|TBC9B_HUMAN TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3;>sp|Q66K14-2|TBC9B_HUMAN Isoform 2 of TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B 0.29984 0 0.29984 0 1.16142E-12 123.81 0 0 0.143023 -5.7076 1.38233E-12 123.36 1.12952E-10 -95.6778 5.32338E-19 138.63 0.00838499 -18.2297 9.42168E-05 94.319 1 S DPSTESSPAPQEG CK1;Polo box;Proline-directed 0.00405 5.32338E-19 138.63 _KASVVDPSTEpSSPAPQEGSEQPASPASPLSSR_ KASVVDPS(0.062)T(0.062)ES(0.3)S(0.3)PAPQEGS(0.196)EQPAS(0.056)PAS(0.015)PLS(0.004)S(0.004)R KAS(-33.24)VVDPS(-6.83)T(-6.83)ES(0)S(0)PAPQEGS(-1.85)EQPAS(-7.26)PAS(-12.96)PLS(-18.48)S(-18.48)R 12 3 1087.5033 -1.1399 0 0 0 0 0 0 0 0 0 1518 1074 432 432 548;2975 624;3384 28342 17601 Mix4_TiO2_Reinj_1_5 4850 28337 17595 Mix4_InSol_TiO2_1 4993 Q66K14;Q66K14-2 Q66K14 Q66K14 >sp|Q66K14|TBC9B_HUMAN TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3;>sp|Q66K14-2|TBC9B_HUMAN Isoform 2 of TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B 0.532312 5.7076 0.137306 -7.8719 1.16142E-12 123.81 0 0 0.532312 5.7076 1.38233E-12 123.36 0.0166372 -13.996 5.32338E-19 138.63 0.0545573 -10.0962 9.42168E-05 94.319 1 S GSEQPASPASPLS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 5.32338E-19 138.63 _KASVVDPSTESSPAPQEGSEQPApSPASPLSSR_ KAS(0.004)VVDPS(0.038)T(0.038)ES(0.143)S(0.143)PAPQEGS(0.038)EQPAS(0.532)PAS(0.038)PLS(0.013)S(0.013)R KAS(-20.97)VVDPS(-11.45)T(-11.45)ES(-5.71)S(-5.71)PAPQEGS(-11.45)EQPAS(5.71)PAS(-11.45)PLS(-16.28)S(-16.28)R 24 3 1087.5033 -0.86085 148920 4.4166 0 0 0 148920 0 0 0 1519 1074 435 435 548;2975 624;3384 5174 3160 Mix4_TiO2_1_5 4329 28337 17595 Mix4_InSol_TiO2_1 4993 Q66K14;Q66K14-2 Q66K14 Q66K14 >sp|Q66K14|TBC9B_HUMAN TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3;>sp|Q66K14-2|TBC9B_HUMAN Isoform 2 of TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B 0.84116 7.8719 0.84116 7.8719 1.16142E-12 123.81 0 0 0.693793 4.38318 1.38233E-12 123.36 0.335669 -0.947658 5.32338E-19 138.63 0.55779 4.91831 9.42168E-05 94.319 1 S QPASPASPLSSRQ CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 5.32338E-19 138.63 _ASVVDPSTESSPAPQEGSEQPASPApSPLSSR_ ASVVDPSTESSPAPQEGSEQPAS(0.137)PAS(0.841)PLS(0.011)S(0.011)R AS(-123.81)VVDPS(-102.3)T(-95.86)ES(-89.4)S(-89.74)PAPQEGS(-59.79)EQPAS(-7.87)PAS(7.87)PLS(-18.93)S(-18.93)R 26 3 1044.805 -0.96017 1950900 57.861 245420 0 0 1627300 0 0 78176 1520 1074 438 438 548;2975 624;3384 28337 17595 Mix4_InSol_TiO2_1 4993 28337 17595 Mix4_InSol_TiO2_1 4993 Q66K14;Q66K14-2 Q66K14 Q66K14 >sp|Q66K14|TBC9B_HUMAN TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3;>sp|Q66K14-2|TBC9B_HUMAN Isoform 2 of TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B 0.41752 0.947658 0.372042 0 1.16142E-12 123.81 0 0 0.0529401 -11.1745 1.38233E-12 123.36 0.41752 0.947658 5.32338E-19 138.63 0.36371 0 9.42168E-05 94.319 1 S SPASPLSSRQSFC CK1;GSK3 0.081 5.32338E-19 138.63 _KASVVDPSTESSPAPQEGSEQPASPASPLpSSR_ KASVVDPSTESSPAPQEGSEQPAS(0.017)PAS(0.336)PLS(0.418)S(0.23)R KAS(-132.41)VVDPS(-105.42)T(-105.42)ES(-95.68)S(-95.68)PAPQEGS(-62.38)EQPAS(-14)PAS(-0.95)PLS(0.95)S(-2.59)R 30 3 1087.5033 -0.2763 0 0 0 0 0 0 0 0 0 1521 1074 439 439 548;2975 624;3384 28339 17597 Mix4_TiO2_1_5 4064 28337 17595 Mix4_InSol_TiO2_1 4993 Q66K14;Q66K14-2 Q66K14 Q66K14 >sp|Q66K14|TBC9B_HUMAN TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3;>sp|Q66K14-2|TBC9B_HUMAN Isoform 2 of TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B 0.372042 0 0.372042 0 1.16142E-12 123.81 0 0 0.252879 -4.38318 1.38233E-12 123.36 0.230174 -2.58621 5.32338E-19 138.63 0.36371 0 9.42168E-05 94.319 1 S PASPLSSRQSFCA CK1 0.143 5.32338E-19 138.63 _KASVVDPSTESSPAPQEGSEQPASPASPLpSSR_ KASVVDPSTESSPAPQEGSEQPASPAS(0.256)PLS(0.372)S(0.372)R KAS(-120.79)VVDPS(-111.82)T(-111.82)ES(-107.55)S(-107.55)PAPQEGS(-69.25)EQPAS(-39.48)PAS(-1.63)PLS(0)S(0)R 31 3 1087.5033 -0.36736 0 0 0 0 0 0 0 0 0 1522 1075 809 809 236 271 2341 1499 Mix4_TiO2_Reinj_1_5 8103 2341 1499 Mix4_TiO2_Reinj_1_5 8103 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.784535 5.61297 0.747767 5.02337 0.00989194 85.358 0.784535 5.61297 0.000403678 98.317 1 S APGAADSDEDTEG CK2 0.117 0.000403678 98.317 _AGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADpSDEDTEGFGVPR_ AGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADS(0.785)DEDT(0.215)EGFGVPR AGGLGAEET(-69.28)PPT(-64.29)S(-64.36)VS(-61.12)ES(-56.67)LPT(-53.27)LS(-48.12)DS(-48.12)DPVPLAPGAADS(5.61)DEDT(-5.61)EGFGVPR 36 3 1559.0413 0.5154 2112000 623000 0 0 1489000 0 0 0 1523 1075 631 631 326 369 3028 1836 Mix4_TiO2_Reinj_1_5 6929 3028 1836 Mix4_TiO2_Reinj_1_5 6929 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.899868 9.59947 0.899868 9.59947 0.00490913 74.896 2 S ELPLAASSIPRPR NEK6 0.076 0.00490913 74.896 _ALELPLAApSpSIPRPRTPSPESHR_ ALELPLAAS(0.9)S(0.893)IPRPRT(0.103)PS(0.103)PES(0.001)HR ALELPLAAS(9.6)S(9.6)IPRPRT(-9.6)PS(-9.6)PES(-32.29)HR 9 3 881.43323 0.14368 639660 0 0 0 639660 0 0 0 1524 1075 632 632 326 369 3028 1836 Mix4_TiO2_Reinj_1_5 6929 3028 1836 Mix4_TiO2_Reinj_1_5 6929 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.893251 9.59947 0.893251 9.59947 0.00490913 74.896 2 S LPLAASSIPRPRT 0.00490913 74.896 _ALELPLAApSpSIPRPRTPSPESHR_ ALELPLAAS(0.9)S(0.893)IPRPRT(0.103)PS(0.103)PES(0.001)HR ALELPLAAS(9.6)S(9.6)IPRPRT(-9.6)PS(-9.6)PES(-32.29)HR 10 3 881.43323 0.14368 639660 0 0 0 639660 0 0 0 1525 1075 759 759 618 712;713 5885 3461 Mix4_TiO2_1_5 3009 5886 3462 Mix4_TiO2_Reinj_1_5 3572 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.973697 16.446 0.973697 16.446 0.0153028 62.951 0 0 0.113879 -8.86808 9.05455E-05 96.359 0.266654 -1.50178 0.000287595 90.928 0.404719 -1.2701 0.0126869 65.899 1 S MAPAPASPGSSND ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 9.05455E-05 96.359 _AVPM(ox)APAPApSPGSSNDSSAR_ AVPMAPAPAS(0.974)PGS(0.022)S(0.004)NDSSAR AVPMAPAPAS(16.45)PGS(-16.45)S(-23.67)NDS(-45.81)S(-45.81)AR 10 2 983.42224 -0.028782 49185 49185 0 0 0 0 0 0 1526 1075 762 762 618 712;713 5886 3462 Mix4_TiO2_Reinj_1_5 3572 5886 3462 Mix4_TiO2_Reinj_1_5 3572 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.877511 8.86808 0.344451 0 0.0153028 62.951 0 0 0.877511 8.86808 9.05455E-05 96.359 0.354794 -0.261489 0.000287595 90.928 0.542205 1.2701 0.0126869 65.899 1 S APASPGSSNDSSA CK1;CK2;GSK3 0.081 9.05455E-05 96.359 _AVPM(ox)APAPASPGpSSNDSSAR_ AVPMAPAPAS(0.114)PGS(0.878)S(0.008)NDSSAR AVPMAPAPAS(-8.87)PGS(8.87)S(-20.17)NDS(-37.58)S(-48.61)AR 13 2 983.42224 0.20271 146270 0 0 0 103350 0 0 42924 1527 1075 763 763 618 712;713 5879 3457 Mix4_InSol_TiO2_1 4376 5886 3462 Mix4_TiO2_Reinj_1_5 3572 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.376813 0.261489 0.292822 -0.705232 0.0153028 62.951 0 0 0.00844466 -20.1667 9.05455E-05 96.359 0.376813 0.261489 0.000287595 90.928 0.114453 -5.68798 0.0126869 65.899 1 S PASPGSSNDSSAR CK1;GSK3 0.081 9.05455E-05 96.359 _AVPMAPAPASPGSpSNDSSAR_ AVPMAPAPAS(0.267)PGS(0.355)S(0.377)NDS(0.001)SAR AVPMAPAPAS(-1.5)PGS(-0.26)S(0.26)NDS(-24.77)S(-28.92)AR 14 2 975.42478 1.0414 0 0 0 0 0 0 0 0 1528 1075 767 767 618 712;713 5883 3459 Mix4_InSol_Tio2_Reinj_1 3737 5886 3462 Mix4_TiO2_Reinj_1_5 3572 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.424058 0.715058 0.00913848 -15.7625 0.0153028 62.951 0 0 1.20835E-05 -48.6106 9.05455E-05 96.359 0.000483322 -28.9189 0.000287595 90.928 0.424058 0.715058 0.0126869 65.899 1 S GSSNDSSARSQER CK1 0.143 9.05455E-05 96.359 _AVPM(ox)APAPASPGSSNDSpSAR_ AVPMAPAPAS(0.069)PGS(0.36)S(0.114)NDS(0.033)S(0.424)AR AVPMAPAPAS(-7.92)PGS(-0.72)S(-5.69)NDS(-11.05)S(0.72)AR 18 2 983.42224 0.34343 0 0 0 0 0 0 0 0 1529 1075 729 729 5122 5827 49568 30280 Mix4_TiO2_1_5 6269 49569 30281 Mix4_TiO2_Reinj_1_5 7034 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.499999 0 0.499999 0 0.00788087 71.384 0.452388 -0.829617 0.000154913 94.609 1 S GPRARRSASPHDV PKA 0.042 0.000154913 94.609 _pSASPHDVDLCLVSPCEFEHR_ S(0.5)AS(0.5)PHDVDLCLVSPCEFEHR S(0)AS(0)PHDVDLCLVS(-56.43)PCEFEHR 1 3 812.34337 -0.80679 71779 71779 0 0 0 0 0 0 1530 1075 731 731 5122 5827 49569 30281 Mix4_TiO2_Reinj_1_5 7034 49569 30281 Mix4_TiO2_Reinj_1_5 7034 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.547612 0.829617 0.499999 0 0.00788087 71.384 0.547612 0.829617 0.000154913 94.609 1 S RARRSASPHDVDL CAMK2;CK2;Proline-directed 0.042 0.000154913 94.609 _SApSPHDVDLCLVSPCEFEHR_ S(0.452)AS(0.548)PHDVDLCLVSPCEFEHR S(-0.83)AS(0.83)PHDVDLCLVS(-86.46)PCEFEHR 3 3 812.34337 -0.96566 462410 71779 0 0 390640 0 0 0 1531 1076 271 271 5096 5797 49277 30065 Mix4_TiO2_Reinj_1_2 3732 49277 30065 Mix4_TiO2_Reinj_1_2 3732 Q66PJ3;Q66PJ3-2;Q66PJ3-3;Q66PJ3-4 Q66PJ3 Q66PJ3 >sp|Q66PJ3|AR6P4_HUMAN ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Homo sapiens GN=ARL6IP4 PE=1 SV=1;>sp|Q66PJ3-2|AR6P4_HUMAN Isoform 2 of ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Homo sapiens GN=ARL6IP4;>sp|Q66PJ 1 117.19 0 0 1 117.19 6.53298E-07 117.19 0 0 0 0 1 S LDQWHRSAGEEED CK2 0.117 6.53298E-07 117.19 _pSAGEEEDGPVLTDEQK_ S(1)AGEEEDGPVLTDEQK S(117.19)AGEEEDGPVLT(-117.19)DEQK 1 2 892.36712 0.92346 44416 0 0 0 44416 0 0 0 1532 1077 660 660 2523 2867 23723 14737 Mix4_InSol_TiO2_1 3429 23729 14743 Mix4_TiO2_Reinj_1_5 3162 Q68CZ2;Q68CZ2-2 Q68CZ2 Q68CZ2 >sp|Q68CZ2|TENS3_HUMAN Tensin-3 OS=Homo sapiens GN=TNS3 PE=1 SV=2;>sp|Q68CZ2-2|TENS3_HUMAN Isoform 2 of Tensin-3 OS=Homo sapiens GN=TNS3 0.986917 19.0555 0.455517 -0.742082 0.0811213 52.349 0 0 0.517829 1.38091 0.000255428 95.771 0.986917 19.0555 0.359931 35.124 0.200546 -5.99902 0.333346 35.939 1 S PDTQQPSPSKAFK CDK1;CDK2;CK1;Proline-directed 0.0057 0.000255428 95.771 _GVGSGPHPPDTQQPpSPSK_ GVGSGPHPPDT(0.001)QQPS(0.987)PS(0.012)K GVGS(-35.12)GPHPPDT(-32.84)QQPS(19.06)PS(-19.06)K 15 2 926.9149 -0.090068 327300 0 0 0 266660 0 60635 0 1533 1077 662 662 2523 2867 23729 14743 Mix4_TiO2_Reinj_1_5 3162 23729 14743 Mix4_TiO2_Reinj_1_5 3162 Q68CZ2;Q68CZ2-2 Q68CZ2 Q68CZ2 >sp|Q68CZ2|TENS3_HUMAN Tensin-3 OS=Homo sapiens GN=TNS3 PE=1 SV=2;>sp|Q68CZ2-2|TENS3_HUMAN Isoform 2 of Tensin-3 OS=Homo sapiens GN=TNS3 0.881645 8.72109 0.836301 7.14265 0.0811213 52.349 0 0 0.881645 8.72109 0.000255428 95.771 0.491665 0 0.359931 35.124 0.798207 5.99902 0.333346 35.939 1 S TQQPSPSKAFKPR 0.000255428 95.771 _GVGSGPHPPDTQQPSPpSK_ GVGSGPHPPDTQQPS(0.118)PS(0.882)K GVGS(-95.77)GPHPPDT(-61.14)QQPS(-8.72)PS(8.72)K 17 2 926.9149 -0.36646 418850 138260 0 0 240180 0 0 40406 1534 1077 776 776 3123 3547 29727 18515 Mix4_InSol_TiO2_1 7639 29727 18515 Mix4_InSol_TiO2_1 7639 Q68CZ2;Q68CZ2-2 Q68CZ2 Q68CZ2 >sp|Q68CZ2|TENS3_HUMAN Tensin-3 OS=Homo sapiens GN=TNS3 PE=1 SV=2;>sp|Q68CZ2-2|TENS3_HUMAN Isoform 2 of Tensin-3 OS=Homo sapiens GN=TNS3 0.999999 62.167 0.973624 15.6719 0.000171471 95.97 0 0 0.999999 62.167 3.58776E-06 102.16 0 0 1 S GRLRKLSLGQYDN AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.001764 3.58776E-06 102.16 _KLpSLGQYDNDAGGQLPFSK_ KLS(1)LGQYDNDAGGQLPFSK KLS(62.17)LGQY(-62.17)DNDAGGQLPFS(-102.16)K 3 2 1059.4988 0.41753 137840 97390 0 0 0 0 40448 0 1535 1077 332 332 6674 7643 67687 41547 Mix4_TiO2_Reinj_1_5 7223 67687 41547 Mix4_TiO2_Reinj_1_5 7223 Q68CZ2;Q68CZ2-3 Q68CZ2 Q68CZ2 >sp|Q68CZ2|TENS3_HUMAN Tensin-3 OS=Homo sapiens GN=TNS3 PE=1 SV=2;>sp|Q68CZ2-3|TENS3_HUMAN Isoform 3 of Tensin-3 OS=Homo sapiens GN=TNS3 0.996694 24.7937 0.973236 15.6071 0.00353389 77.259 0 0 0.996694 24.7937 1.9185E-07 103.44 1 S PLIRWDSYENLSA CAMK2;CHK1;CHK1/2;PKD 0.003192 1.9185E-07 103.44 _WDpSYENLSADGEVLHTQGPVDGSLYAK_ WDS(0.997)Y(0.003)ENLSADGEVLHTQGPVDGSLYAK WDS(24.79)Y(-24.79)ENLS(-60.02)ADGEVLHT(-101.58)QGPVDGS(-101.32)LY(-103.44)AK 3 3 1011.1168 -0.14417 668470 150590 0 0 517880 0 0 0 1536 1079 293 293 555 635 5288 3197 Mix4_TiO2_1_1 2929 5289 3198 Mix4_TiO2_Reinj_1_1 3342 Q68DK2;Q68DK2-2 Q68DK2 Q68DK2 >sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3;>sp|Q68DK2-2|ZFY26_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 0.486327 1.64384 0.486327 1.64384 0.66413 22.926 0 0 0.0030429 -25.1538 0.024623 60.864 0 0 0 0 1 S PPRATASGKVSPD GSK3 0.081 0.024623 60.864 _ATApSGKVSPDHLDPER_ AT(0.181)AS(0.486)GKVS(0.333)PDHLDPER AT(-4.3)AS(1.64)GKVS(-1.64)PDHLDPER 4 3 587.27187 -0.14263 0 0 0 0 0 0 0 0 1537 1079 297 297 555 635 5289 3198 Mix4_TiO2_Reinj_1_1 3342 5289 3198 Mix4_TiO2_Reinj_1_1 3342 Q68DK2;Q68DK2-2 Q68DK2 Q68DK2 >sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3;>sp|Q68DK2-2|ZFY26_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 0.996937 25.1538 0.333077 -1.64384 0.66413 22.926 0 0 0.996937 25.1538 0.024623 60.864 0 0 0 0 1 S TASGKVSPDHLDP CK1;Proline-directed 0.05 0.024623 60.864 _ATASGKVpSPDHLDPER_ ATAS(0.003)GKVS(0.997)PDHLDPER AT(-46.94)AS(-25.15)GKVS(25.15)PDHLDPER 8 3 587.27187 0.14518 192860 0 0 0 192860 0 0 0 1538 1079 700 700 3569 4024 33635 20723 Mix4_TiO2_Reinj_1_1 5163 33635 20723 Mix4_TiO2_Reinj_1_1 5163 Q68DK2;Q68DK2-2 Q68DK2 Q68DK2 >sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3;>sp|Q68DK2-2|ZFY26_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 0.431283 0.967814 0 0 0 0 0.431283 0.967814 0.017124 63.608 0 0 1 S EQLDEISSRSPPE 0.017124 63.608 _LLQEQLDEIpSSRSPPEKPK_ LLQEQLDEIS(0.431)S(0.345)RS(0.224)PPEKPK LLQEQLDEIS(0.97)S(-0.97)RS(-2.85)PPEKPK 10 3 758.71742 0.28063 0 0 0 0 0 0 0 0 1539 1079 1762 1762 5578 6357 54586 33420 Mix4_TiO2_Reinj_1_1 6163 54585 33419 Mix4_TiO2_Reinj_1_1 6025 Q68DK2;Q68DK2-2 Q68DK2 Q68DK2 >sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3;>sp|Q68DK2-2|ZFY26_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 0.970972 15.2451 0.443966 -0.977519 7.68684E-05 96.551 0 0 0.970972 15.2451 7.12186E-05 96.72 0 0 0 0 1 S PETLPRSPSAEFS CK1;ERK/MAPK;NEK6;Proline-directed;WW GroupIV 0.0023175 7.12186E-05 96.72 _pSPSAEFSPAAPPGISSIHSPSLR_ S(0.971)PS(0.029)AEFSPAAPPGISSIHSPSLR S(15.25)PS(-15.25)AEFS(-51.91)PAAPPGIS(-62.82)S(-62.82)IHS(-62.82)PS(-62.82)LR 1 3 791.38092 0.23002 310220 0 0 0 310220 0 0 0 1540 1079 1764 1764 5578 6357 54584 33418 Mix4_TiO2_1_1 5616 54585 33419 Mix4_TiO2_Reinj_1_1 6025 Q68DK2;Q68DK2-2 Q68DK2 Q68DK2 >sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3;>sp|Q68DK2-2|ZFY26_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 0.556034 0.977519 0.556034 0.977519 7.68684E-05 96.551 0 0 0.0290199 -15.2451 7.12186E-05 96.72 0 0 0 0 1 S TLPRSPSAEFSPA CAMK2;CHK1;CHK1/2;GSK3;PKD 0.003192 7.12186E-05 96.72 _SPpSAEFSPAAPPGISSIHSPSLR_ S(0.444)PS(0.556)AEFSPAAPPGISSIHSPSLR S(-0.98)PS(0.98)AEFS(-62.04)PAAPPGIS(-96.55)S(-96.55)IHS(-96.55)PS(-96.55)LR 3 3 791.38092 0.59978 79701 79701 0 0 0 0 0 0 1541 1079 1782 1782 5578 6357 54585 33419 Mix4_TiO2_Reinj_1_1 6025 54585 33419 Mix4_TiO2_Reinj_1_1 6025 Q68DK2;Q68DK2-2 Q68DK2 Q68DK2 >sp|Q68DK2|ZFY26_HUMAN Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 PE=1 SV=3;>sp|Q68DK2-2|ZFY26_HUMAN Isoform 2 of Zinc finger FYVE domain-containing protein 26 OS=Homo sapiens GN=ZFYVE26 0.601753 2.01354 1.23031E-10 -96.5509 7.68684E-05 96.551 0 0 0.601753 2.01354 7.12186E-05 96.72 0 0 0 0 1 S SSIHSPSLRERSF CK2 0.117 7.12186E-05 96.72 _SPSAEFSPAAPPGISSIHSPpSLR_ SPSAEFSPAAPPGIS(0.01)S(0.01)IHS(0.378)PS(0.602)LR S(-96.72)PS(-96.72)AEFS(-87.31)PAAPPGIS(-17.85)S(-17.85)IHS(-2.01)PS(2.01)LR 21 3 791.38092 0.66656 160710 0 0 0 160710 0 0 0 1542 1081 1578 1578 5270;5271 5998;5999 51170 31366 Mix4_InSol_TiO2_1 5113 51161 31363 Mix4_TiO2_Reinj_1_1 4751 Q69YN4;Q69YN4-3 Q69YN4 Q69YN4 >sp|Q69YN4|VIR_HUMAN Protein virilizer homolog OS=Homo sapiens GN=KIAA1429 PE=1 SV=2;>sp|Q69YN4-3|VIR_HUMAN Isoform 3 of Protein virilizer homolog OS=Homo sapiens GN=KIAA1429 0.951989 12.9743 0.0331806 -14.6446 0.00197954 105.05 0.499676 0 0.0987818 38.994 0.0776541 -10.7473 0.00317023 116.3 0.951989 12.9743 0.00035933 107.5 0.499536 0 0.0200183 61.357 1 S SFLSEPSSPGRTK CK1 0.081 0.00317023 116.3 _SFLSEPpSSPGRTK_ SFLSEPS(0.952)S(0.048)PGRTK S(-106.31)FLS(-59.57)EPS(12.97)S(-12.97)PGRT(-48.2)K 7 2 736.84269 0.30206 225560 0 0 0 0 0 225560 0 1543 1081 1579 1579 5270;5271 5998;5999 51161 31363 Mix4_TiO2_Reinj_1_1 4751 51161 31363 Mix4_TiO2_Reinj_1_1 4751 Q69YN4;Q69YN4-3 Q69YN4 Q69YN4 >sp|Q69YN4|VIR_HUMAN Protein virilizer homolog OS=Homo sapiens GN=KIAA1429 PE=1 SV=2;>sp|Q69YN4-3|VIR_HUMAN Isoform 3 of Protein virilizer homolog OS=Homo sapiens GN=KIAA1429 0.999185 30.886 0.994985 22.9751 0.00197954 105.05 0.499676 0 0.0987818 38.994 0.999185 30.886 0.00317023 116.3 0.91954 10.5803 0.00035933 107.5 0.867633 8.26282 0.0200183 61.357 1 S FLSEPSSPGRTKT CDK1;CDK2;CK1;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.00317023 116.3 _SFLSEPSpSPGR_ SFLSEPS(0.001)S(0.999)PGR S(-116.3)FLS(-76.65)EPS(-30.89)S(30.89)PGR 8 2 622.27137 0.11805 1772000 288500 0 0 1116200 0 178000 189280 1544 1081 133 133 6444 7372 65086 39933 Mix4_TiO2_Reinj_1_1 4267 65087 39934 Mix4_TiO2_Reinj_1_5 4759 Q69YN4;Q69YN4-3;Q69YN4-2;Q69YN4-4 Q69YN4 Q69YN4 >sp|Q69YN4|VIR_HUMAN Protein virilizer homolog OS=Homo sapiens GN=KIAA1429 PE=1 SV=2;>sp|Q69YN4-3|VIR_HUMAN Isoform 3 of Protein virilizer homolog OS=Homo sapiens GN=KIAA1429;>sp|Q69YN4-2|VIR_HUMAN Isoform 2 of Protein virilizer homolog OS=Homo sapiens GN= 0.616374 2.09508 0.616374 2.09508 3.49476E-26 171.93 0 0 0 0 1 S SVDRVISHDRDSP CAMK2;CHK1;PKD 0.020748 3.49476E-26 171.93 _VIpSHDRDSPPPPPPPPPPPQPQPSLK_ VIS(0.616)HDRDS(0.38)PPPPPPPPPPPQPQPS(0.003)LK VIS(2.1)HDRDS(-2.1)PPPPPPPPPPPQPQPS(-22.93)LK 3 4 714.36265 0.097089 565790 0 0 0 565790 0 0 0 1545 1081 138 138 6444 7372 65087 39934 Mix4_TiO2_Reinj_1_5 4759 65087 39934 Mix4_TiO2_Reinj_1_5 4759 Q69YN4;Q69YN4-3;Q69YN4-2;Q69YN4-4 Q69YN4 Q69YN4 >sp|Q69YN4|VIR_HUMAN Protein virilizer homolog OS=Homo sapiens GN=KIAA1429 PE=1 SV=2;>sp|Q69YN4-3|VIR_HUMAN Isoform 3 of Protein virilizer homolog OS=Homo sapiens GN=KIAA1429;>sp|Q69YN4-2|VIR_HUMAN Isoform 2 of Protein virilizer homolog OS=Homo sapiens GN= 0.5 0 0.5 0 3.49476E-26 171.93 0 0 0 0 1 S ISHDRDSPPPPPP PKA;Proline-directed 0.042 3.49476E-26 171.93 _VIpSHDRDSPPPPPPPPPPPQPQPSLK_ VIS(0.5)HDRDS(0.5)PPPPPPPPPPPQPQPSLK VIS(0)HDRDS(0)PPPPPPPPPPPQPQPS(-171.93)LK 8 3 952.14777 -0.14349 309740 0 0 0 309740 0 0 0 1546 1082 643 643 388;2967 444;3375 28284 17569 Mix4_TiO2_Reinj_1_5 4304 3716 2215 Mix4_TiO2_Reinj_1_5 4565 Q6AI08 Q6AI08 Q6AI08 >sp|Q6AI08|HEAT6_HUMAN HEAT repeat-containing protein 6 OS=Homo sapiens GN=HEATR6 PE=1 SV=1 0.978273 16.7259 0.965055 14.4154 0.000513436 93.981 0 0 0.978273 16.7259 2.77073E-09 133.7 1 S EETSVSSPKGSSE CDK1;CK1;ERK/MAPK;GSK3;Polo box;Proline-directed 0.0034 2.77073E-09 133.7 _KAPAGPSLEETSVSpSPK_ KAPAGPSLEETS(0.001)VS(0.021)S(0.978)PK KAPAGPS(-45.56)LEET(-39.32)S(-30.9)VS(-16.73)S(16.73)PK 15 3 588.95203 -0.14848 1493800 370840 0 0 1122900 0 0 0 1547 1083 1046 1046 5179 5896 50150 30653 Mix4_TiO2_Reinj_1_5 2221 50150 30653 Mix4_TiO2_Reinj_1_5 2221 Q6AWC2-6;Q6AWC2;Q6AWC2-4;Q6AWC2-2;Q6AWC2-3;Q6AWC2-7 Q6AWC2-6 Q6AWC2-6 >sp|Q6AWC2-6|WWC2_HUMAN Isoform 6 of Protein WWC2 OS=Homo sapiens GN=WWC2;>sp|Q6AWC2|WWC2_HUMAN Protein WWC2 OS=Homo sapiens GN=WWC2 PE=1 SV=2;>sp|Q6AWC2-4|WWC2_HUMAN Isoform 4 of Protein WWC2 OS=Homo sapiens GN=WWC2;>sp|Q6AWC2-2|WWC2_HUMAN Isoform 2 of Pr 0.986075 18.8621 0 0 0.986075 18.8621 0.0850124 39.314 1 S RLNRSDSDSSTLA CAMK2;CHK1;CHK1/2;PKA/AKT;PKD 0.00111111 0.0850124 39.314 _SDpSDSSTLAK_ S(0.013)DS(0.986)DSSTLAK S(-18.86)DS(18.86)DS(-32.97)S(-32.97)T(-39.31)LAK 3 2 545.71863 0.18743 19136 0 0 0 19136 0 0 0 1548 1085 512 512 4332 4927 41148 25305 Mix4_TiO2_1_5 6251 41148 25305 Mix4_TiO2_1_5 6251 Q6DN90;Q6DN90-2 Q6DN90 Q6DN90 >sp|Q6DN90|IQEC1_HUMAN IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens GN=IQSEC1 PE=1 SV=1;>sp|Q6DN90-2|IQEC1_HUMAN Isoform BRAG2a of IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens GN=IQSEC1 0.999977 46.3166 0.999977 46.3166 1.87198E-29 214.57 0 0 1 S HKEARNSWDSPAF PKA 0.042 1.87198E-29 214.57 _NpSWDSPAFSNDVIR_ NS(1)WDSPAFSNDVIR NS(46.32)WDS(-46.32)PAFS(-154.35)NDVIR 2 2 844.35923 0.63286 70624 70624 0 0 0 0 0 0 1549 1085 925 925 5105 5807 49335 30086 Mix4_TiO2_1_5 4690 49335 30086 Mix4_TiO2_1_5 4690 Q6DN90;Q6DN90-2 Q6DN90 Q6DN90 >sp|Q6DN90|IQEC1_HUMAN IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens GN=IQSEC1 PE=1 SV=1;>sp|Q6DN90-2|IQEC1_HUMAN Isoform BRAG2a of IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens GN=IQSEC1 0.839393 7.36128 0.839393 7.36128 0.0083908 74.739 0.831395 7.0732 0.032834 58.814 1 S RSALSSSLRDLSE CK2;NEK6 0.076 0.0083908 74.739 _SALSSpSLRDLSEAGK_ S(0.006)ALS(0.001)S(0.154)S(0.839)LRDLSEAGK S(-21.74)ALS(-29.95)S(-7.36)S(7.36)LRDLS(-46.78)EAGK 6 2 800.88254 0.2586 244480 48817 0 0 195670 0 0 0 1550 1086 773 773 2582 2937 24204 15018 Mix4_TiO2_1_1 6062 24204 15018 Mix4_TiO2_1_1 6062 Q6GYQ0-2;Q6GYQ0-6;Q6GYQ0-5;Q6GYQ0;Q6GYQ0-4;Q6GYQ0-3 Q6GYQ0-2 Q6GYQ0-2 >sp|Q6GYQ0-2|RGPA1_HUMAN Isoform 2 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-6|RGPA1_HUMAN Isoform 6 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-5|RGPA1_HUMAN Isoform 0.479471 0.757067 0.479471 0.757067 0.0134155 66.889 0 0 0 0 1 S TRVRHFSQSEETG CAMK2;CK2;PIM1/2;PKA/AKT 0.000138852 0.0134155 66.889 _HFpSQSEETGNEVFGALNEEQPLPR_ HFS(0.479)QS(0.403)EET(0.118)GNEVFGALNEEQPLPR HFS(0.76)QS(-0.76)EET(-6.1)GNEVFGALNEEQPLPR 3 3 932.41513 -0.20341 0 0 0 0 0 0 0 0 1551 1086 860 860 4900 5572 47051 28772 Mix4_TiO2_Reinj_1_5 4871 47051 28772 Mix4_TiO2_Reinj_1_5 4871 Q6GYQ0-2;Q6GYQ0-6;Q6GYQ0-5;Q6GYQ0;Q6GYQ0-4;Q6GYQ0-3 Q6GYQ0-2 Q6GYQ0-2 >sp|Q6GYQ0-2|RGPA1_HUMAN Isoform 2 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-6|RGPA1_HUMAN Isoform 6 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-5|RGPA1_HUMAN Isoform 0.985295 18.2848 0 0 0 0 0.985295 18.2848 0.0132184 67.418 0 0 0 0 1 S TMTRRGSSPGSLE CAMK2;CHK1;CK1;GSK3;PKA 0.004788 0.0132184 67.418 _RGpSSPGSLEIPK_ RGS(0.985)S(0.015)PGSLEIPK RGS(18.28)S(-18.28)PGS(-40.89)LEIPK 3 2 654.32139 0.090333 437880 0 0 0 437880 0 0 0 1552 1086 796 796 5758 6561 56610 34550 Mix4_TiO2_Reinj_1_1 7167 56611 34551 Mix4_TiO2_Reinj_1_5 7641 Q6GYQ0-2;Q6GYQ0-6;Q6GYQ0-5;Q6GYQ0;Q6GYQ0-4;Q6GYQ0-3 Q6GYQ0-2 Q6GYQ0-2 >sp|Q6GYQ0-2|RGPA1_HUMAN Isoform 2 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-6|RGPA1_HUMAN Isoform 6 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-5|RGPA1_HUMAN Isoform 0.378391 1.27258 0.116325 -8.67365 0.00214442 84.925 0 0 0.378391 1.27258 0.0019469 86.264 0 0 1 S QPLPRSSSTSDIL PKA 0.042 0.0019469 86.264 _SpSSTSDILEPFTVER_ S(0.282)S(0.378)S(0.282)T(0.048)S(0.009)DILEPFTVER S(-1.27)S(1.27)S(-1.27)T(-8.93)S(-16.44)DILEPFT(-65.87)VER 2 2 874.39294 0.26267 0 0 0 0 0 0 0 0 1553 1086 797 797 5758 6561 56609 34549 Mix4_TiO2_1_1 6370 56611 34551 Mix4_TiO2_Reinj_1_5 7641 Q6GYQ0-2;Q6GYQ0-6;Q6GYQ0-5;Q6GYQ0;Q6GYQ0-4;Q6GYQ0-3 Q6GYQ0-2 Q6GYQ0-2 >sp|Q6GYQ0-2|RGPA1_HUMAN Isoform 2 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-6|RGPA1_HUMAN Isoform 6 of Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1;>sp|Q6GYQ0-5|RGPA1_HUMAN Isoform 0.857112 8.67365 0.857112 8.67365 0.00214442 84.925 0 0 0.282282 -1.27258 0.0019469 86.264 0 0 1 S PLPRSSSTSDILE CAMK2;CHK1;CHK1/2;CK2;PKA/AKT;PKD 0.00111111 0.0019469 86.264 _SSpSTSDILEPFTVER_ S(0.012)S(0.116)S(0.857)T(0.012)S(0.002)DILEPFTVER S(-18.41)S(-8.67)S(8.67)T(-18.41)S(-26.73)DILEPFT(-79.07)VER 3 2 874.39294 0.21794 81785 81785 0 0 0 0 0 0 1554 1088 21 21 231 265 2274 1464 Mix4_TiO2_Reinj_1_6 3409 2274 1464 Mix4_TiO2_Reinj_1_6 3409 Q6IQ22 Q6IQ22 Q6IQ22 >sp|Q6IQ22|RAB12_HUMAN Ras-related protein Rab-12 OS=Homo sapiens GN=RAB12 PE=1 SV=3 0.999999 62.2742 0 0 0.999999 62.2742 0.00983539 69.139 1 S GGLGAGSPALSGG GSK3;Proline-directed 0.05 0.00983539 69.139 _AGGGGGLGAGpSPALSGGQGR_ AGGGGGLGAGS(1)PALSGGQGR AGGGGGLGAGS(62.27)PALS(-62.27)GGQGR 11 2 832.38103 0.29076 43282 0 0 0 43282 0 0 0 1555 1089 349 349 57 68 557 354 Mix4_InSol_Tio2_Reinj_1 6151 557 354 Mix4_InSol_Tio2_Reinj_1 6151 Q6KC79;Q6KC79-2;Q6KC79-3 Q6KC79 Q6KC79 >sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein OS=Homo sapiens GN=NIPBL PE=1 SV=2;>sp|Q6KC79-2|NIPBL_HUMAN Isoform IDN3-B of Nipped-B-like protein OS=Homo sapiens GN=NIPBL;>sp|Q6KC79-3|NIPBL_HUMAN Isoform 3 of Nipped-B-like protein OS=Homo sapiens GN=NIPBL 0.742577 4.69214 0 0 0 0 0.0780652 -9.93194 0.0589778 55.091 0.742577 4.69214 0.0284406 59.759 1 S AMYDIISSPSKDS 0.0284406 59.759 _AAMYDIIpSSPSKDSTK_ AAMYDIIS(0.743)S(0.252)PS(0.005)KDSTK AAMY(-38.46)DIIS(4.69)S(-4.69)PS(-21.51)KDS(-59.44)T(-59.76)K 8 2 897.40499 1.3015 50611 0 0 0 0 0 0 50611 1556 1089 350 350 57 68 556 353 Mix4_InSol_TiO2_1 6218 557 354 Mix4_InSol_Tio2_Reinj_1 6151 Q6KC79;Q6KC79-2;Q6KC79-3 Q6KC79 Q6KC79 >sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein OS=Homo sapiens GN=NIPBL PE=1 SV=2;>sp|Q6KC79-2|NIPBL_HUMAN Isoform IDN3-B of Nipped-B-like protein OS=Homo sapiens GN=NIPBL;>sp|Q6KC79-3|NIPBL_HUMAN Isoform 3 of Nipped-B-like protein OS=Homo sapiens GN=NIPBL 0.768514 6.99849 0 0 0 0 0.768514 6.99849 0.0589778 55.091 0.252074 -4.69214 0.0284406 59.759 1 S MYDIISSPSKDST CDK1;CDK2;Polo box;Proline-directed 0.00405 0.0284406 59.759 _AAMYDIISpSPSKDSTK_ AAMYDIIS(0.078)S(0.769)PS(0.153)KDSTK AAMY(-55.09)DIIS(-9.93)S(7)PS(-7)KDS(-47.6)T(-47.6)K 9 2 897.40499 0.3561 80090 0 0 0 0 0 80090 0 1557 1089 2658 2658 287 327 2707 1678 Mix4_TiO2_Reinj_1_1 5825 2707 1678 Mix4_TiO2_Reinj_1_1 5825 Q6KC79;Q6KC79-2 Q6KC79 Q6KC79 >sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein OS=Homo sapiens GN=NIPBL PE=1 SV=2;>sp|Q6KC79-2|NIPBL_HUMAN Isoform IDN3-B of Nipped-B-like protein OS=Homo sapiens GN=NIPBL 1 102.059 1 86.8803 0.00293918 92.367 0 0 1 102.059 0.000220532 116.31 0.999752 39.0727 0.108502 39.073 0.999995 55.8975 0.0325153 55.897 1 S SLLGGGSPKNNTA CDK1;Proline-directed 0.0057 0.000220532 116.31 _AITSLLGGGpSPK_ AITSLLGGGS(1)PK AIT(-108.56)S(-102.06)LLGGGS(102.06)PK 10 2 590.8023 -0.059413 824880 106220 0 0 533270 0 97002 88389 1558 1090 440 440 6541 7484 66056 40536 Mix4_TiO2_Reinj_1_2 5922 66056 40536 Mix4_TiO2_Reinj_1_2 5922 Q6N075 Q6N075 Q6N075 >sp|Q6N075|MFSD5_HUMAN Major facilitator superfamily domain-containing protein 5 OS=Homo sapiens GN=MFSD5 PE=2 SV=2 0.499999 0 0.498927 0 0.369255 23.665 0 0 0.499999 0 0.00547829 78.63 0 0 1 S AELRVPSPTEEPY CAMK2;CK2;ERK/MAPK;Proline-directed 0.0034 0.00547829 78.63 _VPpSPTEEPYAPEL_ VPS(0.5)PT(0.5)EEPYAPEL VPS(0)PT(0)EEPY(-56.65)APEL 3 2 754.83145 -0.11368 144550 0 0 0 144550 0 0 0 1559 1091 63 63 495 561 4582 2772 Mix4_TiO2_Reinj_1_2 2076 4582 2772 Mix4_TiO2_Reinj_1_2 2076 Q6NXT1 Q6NXT1 Q6NXT1 >sp|Q6NXT1|ANR54_HUMAN Ankyrin repeat domain-containing protein 54 OS=Homo sapiens GN=ANKRD54 PE=1 SV=2 1 82.7888 1 67.5212 0.00770393 67.521 1 82.7888 5.26936E-05 82.789 0.999759 36.1827 0.122802 36.183 0.730411 4.32865 0.699474 4.3287 1 S ASGGAQSPLRYLH CDK1;CDK2;Proline-directed 0.0057 5.26936E-05 82.789 _ASGGAQpSPLR_ ASGGAQS(1)PLR AS(-82.79)GGAQS(82.79)PLR 7 2 512.23459 -0.052477 81329 0 0 0 0 0 41446 39883 1560 1092 421 421 2484 2823 23411 14565 Mix4_TiO2_1_1 5521 23411 14565 Mix4_TiO2_1_1 5521 Q6NXT4-2;Q6NXT4;Q6NXT4-3 Q6NXT4-2 Q6NXT4-2 >sp|Q6NXT4-2|ZNT6_HUMAN Isoform 2 of Zinc transporter 6 OS=Homo sapiens GN=SLC30A6;>sp|Q6NXT4|ZNT6_HUMAN Zinc transporter 6 OS=Homo sapiens GN=SLC30A6 PE=1 SV=2;>sp|Q6NXT4-3|ZNT6_HUMAN Isoform 3 of Zinc transporter 6 OS=Homo sapiens GN=SLC30A6 0.499997 0 0.499997 0 1.24021E-18 148.7 0 0 0 0 0 0 0 0 1 S STPAKPSSPPPEF 1.24021E-18 148.7 _GTDDLNPVTSTPAKPpSSPPPEFSFNTPGK_ GTDDLNPVTSTPAKPS(0.5)S(0.5)PPPEFSFNTPGK GT(-116.21)DDLNPVT(-91.5)S(-73.81)T(-53.65)PAKPS(0)S(0)PPPEFS(-51.85)FNT(-58.5)PGK 16 3 1022.4762 -0.41368 197910 197910 0 0 0 0 0 0 1561 1092 422 422 2484 2823 23412 14566 Mix4_TiO2_1_5 5935 23411 14565 Mix4_TiO2_1_1 5521 Q6NXT4-2;Q6NXT4;Q6NXT4-3 Q6NXT4-2 Q6NXT4-2 >sp|Q6NXT4-2|ZNT6_HUMAN Isoform 2 of Zinc transporter 6 OS=Homo sapiens GN=SLC30A6;>sp|Q6NXT4|ZNT6_HUMAN Zinc transporter 6 OS=Homo sapiens GN=SLC30A6 PE=1 SV=2;>sp|Q6NXT4-3|ZNT6_HUMAN Isoform 3 of Zinc transporter 6 OS=Homo sapiens GN=SLC30A6 0.973409 15.6589 0.973409 15.6589 1.24021E-18 148.7 0 0 0 0 0 0 0 0 1 S TPAKPSSPPPEFS ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 1.24021E-18 148.7 _GTDDLNPVTSTPAKPSpSPPPEFSFNTPGK_ GTDDLNPVTSTPAKPS(0.026)S(0.973)PPPEFSFNTPGK GT(-125.31)DDLNPVT(-80.35)S(-70.27)T(-57.6)PAKPS(-15.66)S(15.66)PPPEFS(-38.6)FNT(-51.94)PGK 17 3 1022.4762 -1.1028 325480 325480 0 0 0 0 0 0 1562 1095 152 152 2218;2219 2511;2512 20394 12515 Mix4_TiO2_2_6 1030 20394 12515 Mix4_TiO2_2_6 1030 Q6NZ67 Q6NZ67 Q6NZ67 >sp|Q6NZ67|MZT2B_HUMAN Mitotic-spindle organizing protein 2B OS=Homo sapiens GN=MZT2B PE=1 SV=1 0.999763 36.2534 0.999763 36.2534 0.0774328 39.942 0 0 0 0 0.00374329 -24.2498 0.139463 37.989 1 S GGGPGKSPTRGST CDK1;CDK2;Proline-directed 0.0057 0.0774328 39.942 _GGGPGKpSPTR_ GGGPGKS(1)PTR GGGPGKS(36.25)PT(-36.25)R 7 2 497.22931 0.18425 17229 0 17229 0 0 0 0 0 1563 1097 365 365 4082 4649 38637 23696 Mix4_TiO2_Reinj_1_5 4297 38637 23696 Mix4_TiO2_Reinj_1_5 4297 Q6P0N0;Q6P0N0-2 Q6P0N0 Q6P0N0 >sp|Q6P0N0|KNL2_HUMAN Kinetochore-associated protein KNL-2 homolog OS=Homo sapiens GN=KNL2 PE=1 SV=1;>sp|Q6P0N0-2|KNL2_HUMAN Isoform 2 of Kinetochore-associated protein KNL-2 homolog OS=Homo sapiens GN=KNL2 0.999263 31.3229 0 0 0.999263 31.3229 0.0483978 47.561 1 S RNISKLSPPRIFQ CDK1;CDK2;CK1;Proline-directed 0.0057 0.0483978 47.561 _NISKLpSPPR_ NIS(0.001)KLS(0.999)PPR NIS(-31.32)KLS(31.32)PPR 6 2 546.28408 0.82657 39459 0 0 0 39459 0 0 0 1564 1099 723 723 2356 2666 21818 13560 Mix4_TiO2_Reinj_1_5 8723 21818 13560 Mix4_TiO2_Reinj_1_5 8723 Q6P2E9;Q6P2E9-2 Q6P2E9 Q6P2E9 >sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 PE=1 SV=1;>sp|Q6P2E9-2|EDC4_HUMAN Isoform 2 of Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 0.887414 8.96642 0.213636 -5.65949 0.03391 67.612 0.887414 8.96642 1.3367E-19 151.67 1 S LGLPQASPSRTRS CDK1;CDK2;Proline-directed 0.0057 1.3367E-19 151.67 _GPGQVPTATSALSLELQEVEPLGLPQApSPSR_ GPGQVPTATSALSLELQEVEPLGLPQAS(0.887)PS(0.113)R GPGQVPT(-151.67)AT(-151.67)S(-151.67)ALS(-145.59)LELQEVEPLGLPQAS(8.97)PS(-8.97)R 28 4 803.1577 -0.1254 1443700 0 0 0 1443700 0 0 0 1565 1099 725 725 2356 2666 21816 13558 Mix4_TiO2_1_1 7588 21818 13560 Mix4_TiO2_Reinj_1_5 8723 Q6P2E9;Q6P2E9-2 Q6P2E9 Q6P2E9 >sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 PE=1 SV=1;>sp|Q6P2E9-2|EDC4_HUMAN Isoform 2 of Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 0.786363 5.65949 0.786363 5.65949 0.03391 67.612 0.5 0 1.3367E-19 151.67 1 S LPQASPSRTRSPD GSK3 0.081 1.3367E-19 151.67 _GPGQVPTATSALSLELQEVEPLGLPQASPpSR_ GPGQVPTATSALSLELQEVEPLGLPQAS(0.214)PS(0.786)R GPGQVPT(-67.61)AT(-67.61)S(-67.61)ALS(-67.61)LELQEVEPLGLPQAS(-5.66)PS(5.66)R 30 3 1070.5412 0.20047 251680 45106 0 0 206580 0 0 0 1566 1099 729 729 6200 7082 61455 37252 Mix4_TiO2_1_5 8381 61455 37252 Mix4_TiO2_1_5 8381 Q6P2E9;Q6P2E9-2 Q6P2E9 Q6P2E9 >sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 PE=1 SV=1;>sp|Q6P2E9-2|EDC4_HUMAN Isoform 2 of Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 0.825872 8.09133 0.825872 8.09133 3.51953E-12 126.51 0 0 1 S SPSRTRSPDVISS CAMK2;CK1;Proline-directed 0.042 3.51953E-12 126.51 _TRpSPDVISSASTALSQDIPEIASEALSR_ T(0.128)RS(0.826)PDVIS(0.01)S(0.01)AS(0.013)T(0.013)ALSQDIPEIASEALSR T(-8.09)RS(8.09)PDVIS(-19.32)S(-19.32)AS(-17.92)T(-17.92)ALS(-57.76)QDIPEIAS(-126.51)EALS(-126.51)R 3 3 994.48696 0.13065 446250 446250 0 0 0 0 0 0 1567 1099 734 734 6200 7082 61456 37253 Mix4_TiO2_1_5 8387 61455 37252 Mix4_TiO2_1_5 8381 Q6P2E9;Q6P2E9-2 Q6P2E9 Q6P2E9 >sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 PE=1 SV=1;>sp|Q6P2E9-2|EDC4_HUMAN Isoform 2 of Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 0.449681 5.45198 0.449681 5.45198 3.51953E-12 126.51 0 0 1 S RSPDVISSASTAL 3.51953E-12 126.51 _TRSPDVIpSSASTALSQDIPEIASEALSR_ T(0.128)RS(0.128)PDVIS(0.45)S(0.128)AS(0.128)T(0.037)ALS(0.001)QDIPEIASEALSR T(-5.45)RS(-5.45)PDVIS(5.45)S(-5.45)AS(-5.45)T(-10.83)ALS(-29.09)QDIPEIAS(-68.23)EALS(-70.54)R 8 4 746.11704 0.091219 0 0 0 0 0 0 0 0 1568 1103 544 544 2365;4885 2676;2677;5555;5556 46908 28716 Mix4_TiO2_Reinj_1_3 2694 46908 28716 Mix4_TiO2_Reinj_1_3 2694 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.999992 50.9278 0.999271 31.4032 0.0361482 52.743 0 0 0.999992 50.9278 0.00545129 73.61 0.9741 18.7633 0.363031 18.763 0.99933 31.7451 0.0108627 60.297 1 S RTRRGPSPPASPT CAMK2;GSK3;Proline-directed 0.042 0.00545129 73.61 _RGPpSPPASPTR_ RGPS(1)PPASPTR RGPS(50.93)PPAS(-50.93)PT(-73.61)R 4 2 601.78752 0.36576 3717600 604570 0 0 2460000 0 294740 358210 1569 1103 548 548 2365;4885 2676;2677;5555;5556 46891 28692 Mix4_TiO2_1_3 1892 46894 28700 Mix4_TiO2_Reinj_1_3 2377 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.999911 40.5177 0.999911 40.5177 0.00286226 81.605 0 0 0.999837 37.8672 0.0014996 96.774 0.999435 32.4783 0.174908 32.478 0.999907 40.3009 0.0382369 52.124 2 S GPSPPASPTRKPP CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0014996 96.774 _RGPpSPPApSPTR_ RGPS(1)PPAS(1)PTR RGPS(70.91)PPAS(40.52)PT(-40.52)R 8 2 641.77068 0.19941 3292400 628310 0 0 2319500 0 182710 161850 1570 1103 307 307 5539 6312 54173 33149 Mix4_InSol_TiO2_1 7484 54173 33149 Mix4_InSol_TiO2_1 7484 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.92409 10.9298 0 0 0 0 0 0 0.92409 10.9298 8.85758E-09 125.65 1 S AAALASSPSEGWL CK2;NEK6;Polo box;Proline-directed 0.00405 8.85758E-09 125.65 _SPAAALASpSPSEGWLR_ SPAAALAS(0.001)S(0.924)PS(0.075)EGWLR S(-100.38)PAAALAS(-28.49)S(10.93)PS(-10.93)EGWLR 9 2 840.39308 -0.32806 46363 0 0 0 0 0 46363 0 1571 1103 717 717 6253 7144 62150 37706 Mix4_TiO2_1_4 8095 62158 37717 Mix4_TiO2_Reinj_1_3 8854 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.525616 1.20951 0.525616 1.20951 5.62867E-12 134.41 0.318212 0 0.736971 33.214 0.368656 0 4.67145E-25 171.98 0.292031 0 1.72588 12.464 0.206502 -3.07482 8.78517E-07 100.84 0.373294 0.824573 9.30511E-07 99.822 1 S GFGDRTSTFCGTP PKA 0.042 4.67145E-25 171.98 _TpSTFCGTPEFLAPEVLTQEAYTR_ T(0.398)S(0.526)T(0.071)FCGT(0.006)PEFLAPEVLTQEAYTR T(-1.21)S(1.21)T(-8.71)FCGT(-19.63)PEFLAPEVLT(-105.63)QEAY(-134.19)T(-134.41)R 2 3 900.07506 0.79322 1988600 1988600 0 0 0 0 0 0 1572 1106 425 425 2460 2791 23115 14428 Mix4_TiO2_1_5 4657 23115 14428 Mix4_TiO2_1_5 4657 Q6PCD5 Q6PCD5 Q6PCD5 >sp|Q6PCD5|RFWD3_HUMAN E3 ubiquitin-protein ligase RFWD3 OS=Homo sapiens GN=RFWD3 PE=1 SV=3 0.987934 23.4308 0.987934 23.4308 2.80089E-05 98.568 0.862067 8.85072 0.0213626 62.1 1 S AWVLSCSPSSQGQ NEK6;Proline-directed 0.05 2.80089E-05 98.568 _GSQAWVLSCpSPSSQGQHK_ GSQAWVLS(0.004)CS(0.988)PS(0.004)S(0.004)QGQHK GS(-98.57)QAWVLS(-23.43)CS(23.43)PS(-24.16)S(-24.16)QGQHK 10 3 675.29457 0.20606 291870 68224 0 0 223640 0 0 0 1573 1108 135 135 693 796 6684 3962 Mix4_InSol_TiO2_1 2807 6684 3962 Mix4_InSol_TiO2_1 2807 Q6PGQ7 Q6PGQ7 Q6PGQ7 >sp|Q6PGQ7|BORA_HUMAN Protein aurora borealis OS=Homo sapiens GN=BORA PE=1 SV=2 0.643023 2.55603 0 0 0 0 0.643023 2.55603 0.0702584 46.84 0.261525 -4.49622 0.338574 25.577 1 S KCTNINSDSPVGK CK1 0.143 0.0702584 46.84 _CTNINpSDSPVGKK_ CTNINS(0.643)DS(0.357)PVGKK CT(-46.84)NINS(2.56)DS(-2.56)PVGKK 6 2 750.33163 0.21476 29652 0 0 0 0 0 29652 0 1574 1108 137 137 693 796 6685 3963 Mix4_InSol_Tio2_Reinj_1 2818 6684 3962 Mix4_InSol_TiO2_1 2807 Q6PGQ7 Q6PGQ7 Q6PGQ7 >sp|Q6PGQ7|BORA_HUMAN Protein aurora borealis OS=Homo sapiens GN=BORA PE=1 SV=2 0.736436 4.49622 0 0 0 0 0.356963 -2.55603 0.0702584 46.84 0.736436 4.49622 0.338574 25.577 1 S TNINSDSPVGKKL Proline-directed 0.05 0.0702584 46.84 _CTNINSDpSPVGKK_ CT(0.002)NINS(0.262)DS(0.736)PVGKK CT(-25.58)NINS(-4.5)DS(4.5)PVGKK 8 2 750.33163 0.79611 25518 0 0 0 0 0 0 25518 1575 1109 462 462 1551;6676 1741;7645 67703 41558 Mix4_TiO2_1_5 5128 67702 41556 Mix4_TiO2_1_4 5159 Q6PHR2 Q6PHR2 Q6PHR2 >sp|Q6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 OS=Homo sapiens GN=ULK3 PE=1 SV=2 0.97539 15.9808 0.97539 15.9808 2.07022E-21 194.81 0 0 0.700275 3.68827 1.11086E-12 151 0 0 0.0908809 -9.54407 1.12556 9.5441 0.419765 -0.864971 9.33931E-09 124.99 1 S LDKEGLSESVRSS 2.07022E-21 194.81 _WEADTLDKEGLpSESVR_ WEADTLDKEGLS(0.975)ES(0.025)VR WEADT(-59.81)LDKEGLS(15.98)ES(-15.98)VR 12 3 638.95421 0.97602 138170 51534 0 0 86637 0 0 0 1576 1109 464 464 1551;6676 1741;7645 67702 41556 Mix4_TiO2_1_4 5159 67702 41556 Mix4_TiO2_1_4 5159 Q6PHR2 Q6PHR2 Q6PHR2 >sp|Q6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 OS=Homo sapiens GN=ULK3 PE=1 SV=2 0.999328 31.7255 0.999328 31.7255 2.07022E-21 194.81 0 0 0.983952 17.8756 1.11086E-12 151 0 0 0.818238 9.54407 1.12556 9.5441 0.988809 22.4728 9.33931E-09 124.99 1 S KEGLSESVRSSCT GSK3;NEK6 0.076 2.07022E-21 194.81 _WEADTLDKEGLSEpSVR_ WEADTLDKEGLS(0.001)ES(0.999)VR WEADT(-140.02)LDKEGLS(-31.73)ES(31.73)VR 14 2 957.92768 0.12832 6853400 1526800 0 0 4871300 0 222340 232930 1577 1109 219 219 5272 6000 51176 31368 Mix4_TiO2_1_4 4617 51177 31369 Mix4_TiO2_Reinj_1_4 5411 Q6PHR2 Q6PHR2 Q6PHR2 >sp|Q6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 OS=Homo sapiens GN=ULK3 PE=1 SV=2 0.998299 27.6861 0.998299 27.6861 0.378675 27.686 0.996936 25.1232 0.0159304 67.424 1 S FASRSFSELEEKI CAMK2;CK1;CK2 0.042 0.0159304 67.424 _SFpSELEEK_ S(0.002)FS(0.998)ELEEK S(-27.69)FS(27.69)ELEEK 3 2 524.71536 0.0053885 80341 18529 0 0 61812 0 0 0 1578 1110 461 461 4817;5018 5467;5707 48471 29658 Mix4_TiO2_Reinj_1_5 5923 48471 29658 Mix4_TiO2_Reinj_1_5 5923 Q6PJG2 Q6PJG2 Q6PJG2 >sp|Q6PJG2|CN043_HUMAN Uncharacterized protein C14orf43 OS=Homo sapiens GN=C14orf43 PE=1 SV=2 1 77.1422 0.999999 58.6976 0.0302499 58.698 1 77.1422 0.00564949 77.142 1 S RRRRRASQEANLL CAMK2;PKA;PKA/AKT 0.001764 0.00564949 77.142 _RRApSQEANLLTLAQK_ RRAS(1)QEANLLTLAQK RRAS(77.14)QEANLLT(-77.14)LAQK 4 3 593.64728 -0.010665 377520 80541 0 0 296980 0 0 0 1579 1110 661 661 5260 5988 51077 31276 Mix4_TiO2_1_5 7678 51077 31276 Mix4_TiO2_1_5 7678 Q6PJG2 Q6PJG2 Q6PJG2 >sp|Q6PJG2|CN043_HUMAN Uncharacterized protein C14orf43 OS=Homo sapiens GN=C14orf43 PE=1 SV=2 0.999939 41.9928 0.999939 41.9928 0.10362 48.754 2 S TPPPILSPVREGS CDK1;CDK2;Proline-directed 0.0057 0.10362 48.754 _SFELPPYpTPPPILpSPVR_ SFELPPY(0.317)T(0.683)PPPILS(1)PVR S(-48.75)FELPPY(-3.34)T(3.34)PPPILS(41.99)PVR 14 2 1035.4911 0.28104 18465 18465 0 0 0 0 0 0 1580 1112 515 515 1040 1167 9831 6021 Mix4_TiO2_Reinj_1_3 3438 9831 6021 Mix4_TiO2_Reinj_1_3 3438 Q6PJT7;Q6PJT7-2;Q6PJT7-5;Q6PJT7-7 Q6PJT7 Q6PJT7 >sp|Q6PJT7|ZC3HE_HUMAN Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens GN=ZC3H14 PE=1 SV=1;>sp|Q6PJT7-2|ZC3HE_HUMAN Isoform 2 of Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens GN=ZC3H14;>sp|Q6PJT7-5|ZC3HE_HUMAN Isoform 5 of Zin 1 59.7923 1 39.9132 0.0981298 39.913 1 59.7923 0.0187593 59.792 1 38.4821 0.115797 38.482 1 30.1853 0.218232 30.185 1 S QPDKPASPKFIVT CDK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0187593 59.792 _DLVQPDKPApSPK_ DLVQPDKPAS(1)PK DLVQPDKPAS(59.79)PK 10 2 687.83687 0.23596 631810 93589 0 0 307790 0 115730 114700 1581 1113 90 90 1827 2063 16767 10108 Mix4_TiO2_Reinj_1_5 6141 16767 10108 Mix4_TiO2_Reinj_1_5 6141 Q6PKG0 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2 1 104.8 1 64.1956 6.59765E-11 122.82 1 104.8 8.57482E-35 176.08 1 S AEGPAISDGEEGG CK2 0.117 8.57482E-35 176.08 _ESPRPLQLPGAEGPAIpSDGEEGGGEPGAGGGAAGAAGAGR_ ESPRPLQLPGAEGPAIS(1)DGEEGGGEPGAGGGAAGAAGAGR ES(-104.8)PRPLQLPGAEGPAIS(104.8)DGEEGGGEPGAGGGAAGAAGAGR 17 3 1203.2185 -0.11905 6916800 9.4686 1955100 0 0 4961800 0 0 0 1582 1113 517 517 1862;4567 2103;2104;5186;5187 17135 10326 Mix4_TiO2_1_5 1368 43266 26534 Mix4_InSol_TiO2_1 2544 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.999133 30.611 0.999133 30.611 0.190044 30.611 0.068828 -11.2428 0.385137 17.904 0.99541 23.33 0.277913 23.33 0.838062 7.14161 0.126719 41.938 0.693188 5.89791 1.08921 7.7897 2 S YQKETESAPGSPR GSK3 0.081 0.126719 41.938 _ETEpSAPGpSPR_ ET(0.002)ES(0.999)APGS(0.999)PR ET(-28.62)ES(30.61)APGS(28.62)PR 4 2 595.70996 0.23819 479860 59756 0 0 232690 0 55681 131730 1583 1113 521 521 1862;4567 2103;2104;5186;5187 17125 10322 Mix4_TiO2_1_5 1332 17127 10324 Mix4_TiO2_Reinj_1_3 1853 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.986531 19.5406 0.986531 19.5406 0.246209 25.957 0.916325 11.2428 0.385137 17.904 0.933886 11.5698 0.13714 29.474 0.999839 41.9375 0.126719 41.938 0.740423 7.78972 1.08921 7.7897 1 S TESAPGSPRAVTP CDK1;CK1;ERK/MAPK;Proline-directed 0.0025 0.13714 29.474 _ETESAPGpSPR_ ET(0.003)ES(0.011)APGS(0.987)PR ET(-25.96)ES(-19.54)APGS(19.54)PR 8 2 555.72679 -0.28021 320590 54163 6831.4 0 259590 0 0 0 1584 1113 546 546 2318 2623 21488 13165 Mix4_TiO2_1_6 6374 21492 13169 Mix4_TiO2_Reinj_1_5 8278 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.973555 15.6603 0.973555 15.6603 1.99224E-15 145.36 0.0496712 -12.8177 0.000568188 91.957 0.498691 0 6.23211E-23 175.82 0 0 0.572647 1.27128 0.00149701 80.631 0.579314 1.38955 6.12943E-06 100.92 1 S TLPKGLSASLPDL CHK1;PKD 0.020748 6.23211E-23 175.82 _GLpSASLPDLDSENWIEVK_ GLS(0.974)AS(0.026)LPDLDSENWIEVK GLS(15.66)AS(-15.66)LPDLDS(-59.97)ENWIEVK 3 2 1026.9799 0.077254 1553800 660010 0 0 0 0 525850 367950 1585 1113 548 548 2318 2623 21492 13169 Mix4_TiO2_Reinj_1_5 8278 21492 13169 Mix4_TiO2_Reinj_1_5 8278 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.988418 19.3115 0.405366 -1.66403 1.99224E-15 145.36 0.950328 12.8177 0.000568188 91.957 0.988418 19.3115 6.23211E-23 175.82 0 0 0.826641 6.78371 0.00149701 80.631 0.499835 0 6.12943E-06 100.92 1 S PKGLSASLPDLDS CK2;NEK6 0.076 6.23211E-23 175.82 _GLSApSLPDLDSENWIEVK_ GLS(0.012)AS(0.988)LPDLDSENWIEVK GLS(-19.31)AS(19.31)LPDLDS(-130.09)ENWIEVK 5 2 1026.9799 0.37865 4183700 0 38616 0 4043400 0 101670 0 1586 1113 627 627 4340 4937 41208 25332 Mix4_TiO2_1_5 5930 41207 25331 Mix4_TiO2_1_5 5902 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.651923 4.61527 0.651923 4.61527 3.3144E-11 126.21 0.531091 1.0639 0.000484938 83.317 1 S NTFTAWSDEESDY CK2;GSK3 0.081 3.3144E-11 126.21 _NTFTAWpSDEESDYEIDDRDVNK_ NT(0.225)FT(0.07)AWS(0.652)DEES(0.026)DY(0.026)EIDDRDVNK NT(-4.62)FT(-9.68)AWS(4.62)DEES(-13.94)DY(-13.94)EIDDRDVNK 7 2 1365.048 0.090971 732000 55164 0 0 676830 0 0 0 1587 1113 631 631 4340 4937 41207 25331 Mix4_TiO2_1_5 5902 41207 25331 Mix4_TiO2_1_5 5902 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.78012 7.79722 0.78012 7.79722 3.3144E-11 126.21 0.415699 -1.0639 0.000484938 83.317 1 S AWSDEESDYEIDD CK1;CK2 0.117 3.3144E-11 126.21 _NTFTAWSDEEpSDYEIDDRDVNK_ NTFTAWS(0.13)DEES(0.78)DY(0.09)EIDDRDVNK NT(-105.64)FT(-89.7)AWS(-7.8)DEES(7.8)DY(-9.36)EIDDRDVNK 11 3 910.36774 0.2533 175730 175730 0 0 0 0 0 0 1588 1113 766 766 5459 6211;6212 53217 32535 Mix4_TiO2_1_5 4613 53216 32533 Mix4_TiO2_1_5 4341 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.999988 49.8989 0.999988 49.8989 0.000396588 106.22 0.000103854 -39.5657 0.114168 39.566 0.999454 38.6452 0.00578397 78.268 0 0 0.997959 29.916 0.0327953 57.02 0.911771 12.7321 0.107995 39.95 1 S PSTIARSLPTTVP CK1 0.143 0.000396588 106.22 _pSLPTTVPESPNYR_ S(1)LPTTVPESPNYR S(49.9)LPT(-49.9)T(-56.86)VPES(-80.09)PNY(-80.09)R 1 2 770.8558 1.1439 508390 119370 0 0 389020 0 0 0 1589 1113 774 774 5459 6211;6212 53216 32533 Mix4_TiO2_1_5 4341 53216 32533 Mix4_TiO2_1_5 4341 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.999861 38.5719 0.999861 38.5719 0.000396588 106.22 0.939715 11.9504 0.114168 39.566 0.998402 27.9626 0.00578397 78.268 0 0 0.98698 18.7969 0.000601709 99.169 0.993454 21.8129 0.0140325 68.469 1 S PTTVPESPNYRNT CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 0.000396588 106.22 _SLPTTVPEpSPNYR_ SLPTTVPES(1)PNYR S(-106.22)LPT(-106.22)T(-102.29)VPES(38.57)PNY(-38.57)R 9 2 770.8558 0.24869 3062900 694210 84071 0 1441500 0 475970 367110 1590 1113 847 847 5905 6735 58261 35361 Mix4_TiO2_1_5 4975 58261 35361 Mix4_TiO2_1_5 4975 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.52573 0.748424 0.52573 0.748424 0.0156409 68.77 1 S HRPRTASISSSPS CAMK2;GSK3;PKA/AKT 0.00111111 0.0156409 68.77 _TApSISSSPSEGTPTVGSYGCTPQSLPK_ T(0.443)AS(0.526)IS(0.024)S(0.006)S(0.001)PSEGTPTVGSYGCTPQSLPK T(-0.75)AS(0.75)IS(-13.35)S(-19.71)S(-25.84)PS(-31.2)EGT(-41.26)PT(-47.37)VGS(-63.06)Y(-61.75)GCT(-68.77)PQS(-68.77)LPK 3 3 926.08428 1.4828 45601 45601 0 0 0 0 0 0 1591 1114 21 21 2411;3979 2732;4533 37661 23124 Mix4_TiO2_1_1 4802 37661 23124 Mix4_TiO2_1_1 4802 Q6R327-3;Q6R327;Q6R327-4 Q6R327-3 Q6R327-3 >sp|Q6R327-3|RICTR_HUMAN Isoform 3 of Rapamycin-insensitive companion of mTOR OS=Homo sapiens GN=RICTOR;>sp|Q6R327|RICTR_HUMAN Rapamycin-insensitive companion of mTOR OS=Homo sapiens GN=RICTOR PE=1 SV=1;>sp|Q6R327-4|RICTR_HUMAN Isoform 2 of Rapamycin-insen 1 80.9912 1 80.9912 0.00317802 80.991 0.999999 62.0031 0.0219368 62.003 1 S VRGRNDSGEENVP CAMK2;CK2;PKA/AKT 0.001764 0.00317802 80.991 _NDpSGEENVPLDLTR_ NDS(1)GEENVPLDLTR NDS(80.99)GEENVPLDLT(-80.99)R 3 2 819.85398 1.0117 367710 23127 0 0 344590 0 0 0 1592 1116 459 459 3758 4239 35492 21919 Mix4_TiO2_1_6 6462 35492 21919 Mix4_TiO2_1_6 6462 Q6SZW1;Q6SZW1-2 Q6SZW1 Q6SZW1 >sp|Q6SZW1|SARM1_HUMAN Sterile alpha and TIR motif-containing protein 1 OS=Homo sapiens GN=SARM1 PE=1 SV=1;>sp|Q6SZW1-2|SARM1_HUMAN Isoform 2 of Sterile alpha and TIR motif-containing protein 1 OS=Homo sapiens GN=SARM1 0.969247 14.9864 0.969247 14.9864 0.0650688 54.527 0.45599 0 1.20895 10.154 1 S TDLGMKSGITRKR 0.0650688 54.527 _LTEEELQTDLGM(ox)KpSGITR_ LTEEELQTDLGMKS(0.969)GIT(0.031)R LT(-54.53)EEELQT(-54.53)DLGMKS(14.99)GIT(-14.99)R 14 2 1058.9952 0.35474 20985 20985 0 0 0 0 0 0 1593 1117 518 518 3223 3655 30527 18967 Mix4_TiO2_Reinj_1_5 1784 30527 18967 Mix4_TiO2_Reinj_1_5 1784 Q6ULP2;Q6ULP2-4;Q6ULP2-2;Q6ULP2-5;Q6ULP2-3 Q6ULP2 Q6ULP2 >sp|Q6ULP2|AFTIN_HUMAN Aftiphilin OS=Homo sapiens GN=AFTPH PE=1 SV=2;>sp|Q6ULP2-4|AFTIN_HUMAN Isoform 4 of Aftiphilin OS=Homo sapiens GN=AFTPH;>sp|Q6ULP2-2|AFTIN_HUMAN Isoform 2 of Aftiphilin OS=Homo sapiens GN=AFTPH;>sp|Q6ULP2-5|AFTIN_HUMAN Isoform 5 of A 0.966651 15.6719 0 0 0.966651 15.6719 0.1436 36.23 1 S QLARKSSGTGTEP CAMK2;CHK1;CHK1/2;PKA;PKD 0.003192 0.1436 36.23 _KSpSGTGTEPVAK_ KS(0.003)S(0.967)GT(0.026)GT(0.004)EPVAK KS(-24.86)S(15.67)GT(-15.67)GT(-23.83)EPVAK 3 2 621.2923 0.14973 48437 0 0 0 48437 0 0 0 1594 1118 299 299 3188 3618 30262 18835 Mix4_TiO2_1_4 3813 30263 18836 Mix4_TiO2_1_4 3821 Q6UX15;Q6UX15-2 Q6UX15 Q6UX15 >sp|Q6UX15|LAYN_HUMAN Layilin OS=Homo sapiens GN=LAYN PE=2 SV=1;>sp|Q6UX15-2|LAYN_HUMAN Isoform 2 of Layilin OS=Homo sapiens GN=LAYN 0.999997 55.5203 0.999997 55.5203 0.000343381 97.112 0 0 0.999874 38.9796 0.0204837 64.141 0 0 0 0 0 0 1 S NVIRKQSEADLAE CAMK2;CHK1;CK2;PKA;PKD 0.004788 0.000343381 97.112 _KQpSEADLAETRPDLK_ KQS(1)EADLAETRPDLK KQS(55.52)EADLAET(-55.52)RPDLK 3 3 594.28741 0.10591 1165400 289240 0 0 876170 0 0 0 1595 1120 493 493 5936 6769 58502 35477 Mix4_TiO2_Reinj_1_5 4220 58502 35477 Mix4_TiO2_Reinj_1_5 4220 Q6VY07-2;Q6VY07 Q6VY07-2 Q6VY07-2 >sp|Q6VY07-2|PACS1_HUMAN Isoform 2 of Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens GN=PACS1;>sp|Q6VY07|PACS1_HUMAN Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens GN=PACS1 PE=1 SV=2 0.794146 6.61466 0 0 0.794146 6.61466 0.123727 47.563 1 S KTDLQGSASPSKV GSK3;NEK6 0.076 0.123727 47.563 _TDLQGpSASPSKVEGVHTPR_ T(0.002)DLQGS(0.794)AS(0.173)PS(0.031)KVEGVHTPR T(-27.06)DLQGS(6.61)AS(-6.61)PS(-14.08)KVEGVHT(-40.81)PR 6 3 682.65991 0.33866 120960 0 0 0 120960 0 0 0 1596 1121 1371 1371 5349 6090 51964 31814 Mix4_TiO2_Reinj_1_5 1914 51964 31814 Mix4_TiO2_Reinj_1_5 1914 Q6XZF7;Q6XZF7-2 Q6XZF7 Q6XZF7 >sp|Q6XZF7|DNMBP_HUMAN Dynamin-binding protein OS=Homo sapiens GN=DNMBP PE=1 SV=1;>sp|Q6XZF7-2|DNMBP_HUMAN Isoform 2 of Dynamin-binding protein OS=Homo sapiens GN=DNMBP 0.950134 15.8143 0.950134 15.8143 1.88598E-07 114.4 1 S SEHGSSSPRFPRQ CDK1;Polo box;Proline-directed 0.00405 1.88598E-07 114.4 _SHSDASVGSHSSTESEHGSSpSPR_ SHSDASVGSHSSTESEHGS(0.025)S(0.025)S(0.95)PR S(-114.4)HS(-114.4)DAS(-95.67)VGS(-74.84)HS(-74.84)S(-69.71)T(-63.52)ES(-42.95)EHGS(-15.81)S(-15.81)S(15.81)PR 21 3 797.98596 -0.2692 99093 0 0 0 99093 0 0 0 1597 1122 26 26 357 408 3338 2006 Mix4_TiO2_1_5 5696 3338 2006 Mix4_TiO2_1_5 5696 Q6Y7W6-3;Q6Y7W6 Q6Y7W6-3 Q6Y7W6-3 >sp|Q6Y7W6-3|PERQ2_HUMAN Isoform 2 of PERQ amino acid-rich with GYF domain-containing protein 2 OS=Homo sapiens GN=GIGYF2;>sp|Q6Y7W6|PERQ2_HUMAN PERQ amino acid-rich with GYF domain-containing protein 2 OS=Homo sapiens GN=GIGYF2 PE=1 SV=1 0.996472 26.0378 0.996472 26.0378 1.73329E-15 140.38 0.995783 25.1576 0.00567277 75.019 0.996102 25.4107 2.35176E-10 129.1 0.97958 17.5491 0.000617725 88.324 0.945509 13.0272 0.0593921 55.474 1 S SGGSITSPPLSPA CK1;GSK3;Proline-directed 0.05 1.73329E-15 140.38 _ALSSGGSITpSPPLSPALPK_ ALSSGGSIT(0.002)S(0.996)PPLS(0.001)PALPK ALS(-71.16)S(-79.59)GGS(-49.66)IT(-26.04)S(26.04)PPLS(-29.83)PALPK 10 2 930.47935 0.23567 1656800 287950 78641 0 968840 0 181070 140250 1598 1122 406 406 6423 7347 64864 39798 Mix4_TiO2_Reinj_1_5 4471 64863 39797 Mix4_TiO2_Reinj_1_5 4440 Q6Y7W6-3;Q6Y7W6 Q6Y7W6-3 Q6Y7W6-3 >sp|Q6Y7W6-3|PERQ2_HUMAN Isoform 2 of PERQ amino acid-rich with GYF domain-containing protein 2 OS=Homo sapiens GN=GIGYF2;>sp|Q6Y7W6|PERQ2_HUMAN PERQ amino acid-rich with GYF domain-containing protein 2 OS=Homo sapiens GN=GIGYF2 PE=1 SV=1 0.34483 0 0 0 0.00382454 -24.0456 0.000131099 95.531 0.34483 0 1.55276E-07 109.98 0 0 0 0 0.067569 -6.03075 1.45192 38.254 1 S ARPGTPSDHQSQE GSK3 0.081 1.55276E-07 109.98 _VGVEASEETPQTSSSSARPGpTPSDHQSQEASQFER_ VGVEASEET(0.006)PQT(0.019)S(0.074)S(0.074)S(0.074)S(0.025)ARPGT(0.345)PS(0.345)DHQS(0.007)QEAS(0.032)QFER VGVEAS(-37.01)EET(-17.7)PQT(-12.57)S(-6.7)S(-6.7)S(-6.7)S(-11.46)ARPGT(0)PS(0)DHQS(-16.66)QEAS(-10.33)QFER 23 4 946.6646 -0.25402 0 0 0 0 0 0 0 0 1599 1125 1301 1301 3810 4305 36226 22379 Mix4_TiO2_Reinj_1_1 5920 36226 22379 Mix4_TiO2_Reinj_1_1 5920 Q6ZNJ1 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2 0.999957 46.0306 0.999957 46.0306 1.49701E-17 138.31 2 S EAATAGSPPPSSP GSK3;Proline-directed 0.05 1.49701E-17 138.31 _LYVLEAATAGpSPPPSSPEpSPTSPK_ LYVLEAATAGS(1)PPPSSPES(0.833)PT(0.142)S(0.025)PK LY(-105.47)VLEAAT(-46.03)AGS(46.03)PPPS(-47.38)S(-39.66)PES(7.68)PT(-7.68)S(-15.28)PK 11 3 848.38332 -0.13349 150520 0 0 0 150520 0 0 0 1600 1125 1309 1309 3810 4305 36226 22379 Mix4_TiO2_Reinj_1_1 5920 36226 22379 Mix4_TiO2_Reinj_1_1 5920 Q6ZNJ1 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2 0.833132 7.68191 0.833132 7.68191 1.49701E-17 138.31 2 S PPSSPESPTSPKP CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 1.49701E-17 138.31 _LYVLEAATAGpSPPPSSPEpSPTSPK_ LYVLEAATAGS(1)PPPSSPES(0.833)PT(0.142)S(0.025)PK LY(-105.47)VLEAAT(-46.03)AGS(46.03)PPPS(-47.38)S(-39.66)PES(7.68)PT(-7.68)S(-15.28)PK 19 3 848.38332 -0.13349 150520 0 0 0 150520 0 0 0 1601 1125 2739 2739 4920 5594 47226 28846 Mix4_TiO2_1_1 3621 47229 28849 Mix4_TiO2_Reinj_1_1 4075 Q6ZNJ1;Q6ZNJ1-2;Q6ZNJ1-3 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2;>sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like protein 2 OS=Homo sap 0.999964 44.4414 0.999964 44.4414 1.16006E-06 114.86 0 0 0.999913 40.626 1.85885E-15 146.09 0 0 0.998846 30.3167 0.00483705 76.677 1 S RSSRRISQVSSGE CAMK2;CK1;GSK3;PKA 0.004788 1.85885E-15 146.09 _RIpSQVSSGETEYNPTEAR_ RIS(1)QVSSGETEYNPTEAR RIS(44.44)QVS(-44.44)S(-71.21)GET(-76.54)EY(-98.04)NPT(-98.04)EAR 3 2 1052.4708 0.51581 504120 120890 0 0 315880 0 0 67353 1602 1125 2742 2742 4920 5594 47227 28847 Mix4_TiO2_1_1 3635 47229 28849 Mix4_TiO2_Reinj_1_1 4075 Q6ZNJ1;Q6ZNJ1-2;Q6ZNJ1-3 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2;>sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like protein 2 OS=Homo sap 0.587231 3.06787 0.587231 3.06787 1.16006E-06 114.86 0 0 0.332631 0 1.85885E-15 146.09 0 0 0.000928592 -30.3167 0.00483705 76.677 1 S RRISQVSSGETEY CK1;CK2 0.081 1.85885E-15 146.09 _RISQVpSSGETEYNPTEAR_ RIS(0.29)QVS(0.587)S(0.123)GETEYNPTEAR RIS(-3.07)QVS(3.07)S(-6.79)GET(-39.79)EY(-87.9)NPT(-114.86)EAR 6 3 701.98294 -0.12365 67870 67870 0 0 0 0 0 0 1603 1125 2743 2743 4920 5594 47229 28849 Mix4_TiO2_Reinj_1_1 4075 47229 28849 Mix4_TiO2_Reinj_1_1 4075 Q6ZNJ1;Q6ZNJ1-2;Q6ZNJ1-3 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2;>sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like protein 2 OS=Homo sap 0.332631 0 0.122959 -6.7905 1.16006E-06 114.86 0 0 0.332631 0 1.85885E-15 146.09 0 0 0.00022549 -36.4637 0.00483705 76.677 1 S RISQVSSGETEYN CK1 0.143 1.85885E-15 146.09 _RIpSQVSSGETEYNPTEAR_ RIS(0.333)QVS(0.333)S(0.333)GET(0.002)EYNPTEAR RIS(0)QVS(0)S(0)GET(-21.98)EY(-94.88)NPT(-146.09)EAR 7 3 701.98294 -0.32215 0 0 0 0 0 0 0 0 1604 1125 759 759 5651 6437 55177 33765 Mix4_TiO2_Reinj_1_1 8195 55177 33765 Mix4_TiO2_Reinj_1_1 8195 Q6ZNJ1;Q6ZNJ1-2 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 0.481172 0.730464 0.410548 0.461086 0.13129 67.474 0 0 0.481172 0.730464 9.8556E-09 117.95 1 S ALTRSQSVPASTG 14-3-3 binding;CAMK2;CHK1;CHK1/2;CK1;GSK3;PKD 0.0001701 9.8556E-09 117.95 _SQpSVPASTGLGWGSGLVAPLQEGSIDSTLAGTQDTR_ S(0.407)QS(0.481)VPAS(0.056)T(0.056)GLGWGSGLVAPLQEGSIDSTLAGTQDTR S(-0.73)QS(0.73)VPAS(-9.34)T(-9.34)GLGWGS(-39.44)GLVAPLQEGS(-93)IDS(-104.44)T(-104.44)LAGT(-114.38)QDT(-116.35)R 3 3 1208.579 0.12667 0 0 0 0 0 0 0 0 1605 1125 763 763 5651 6437 55178 33767 Mix4_TiO2_Reinj_1_1 8215 55177 33765 Mix4_TiO2_Reinj_1_1 8195 Q6ZNJ1;Q6ZNJ1-2 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 0.244367 0 0.108032 -5.79812 0.13129 67.474 0 0 0.244367 0 9.8556E-09 117.95 1 S SQSVPASTGLGWG CK1 0.143 9.8556E-09 117.95 _SQSVPApSTGLGWGSGLVAPLQEGSIDSTLAGTQDTR_ S(0.2)QS(0.066)VPAS(0.244)T(0.244)GLGWGS(0.244)GLVAPLQEGSIDSTLAGTQDTR S(-0.86)QS(-5.7)VPAS(0)T(0)GLGWGS(0)GLVAPLQEGS(-31.58)IDS(-31.43)T(-31.58)LAGT(-39.82)QDT(-40.99)R 7 4 906.68608 0.11573 0 0 0 0 0 0 0 0 1606 1125 770 770 5651 6437 55178 33767 Mix4_TiO2_Reinj_1_1 8215 55177 33765 Mix4_TiO2_Reinj_1_1 8195 Q6ZNJ1;Q6ZNJ1-2 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 0.244367 0 0.00418911 -19.9124 0.13129 67.474 0 0 0.244367 0 9.8556E-09 117.95 1 S TGLGWGSGLVAPL 9.8556E-09 117.95 _SQSVPApSTGLGWGSGLVAPLQEGSIDSTLAGTQDTR_ S(0.2)QS(0.066)VPAS(0.244)T(0.244)GLGWGS(0.244)GLVAPLQEGSIDSTLAGTQDTR S(-0.86)QS(-5.7)VPAS(0)T(0)GLGWGS(0)GLVAPLQEGS(-31.58)IDS(-31.43)T(-31.58)LAGT(-39.82)QDT(-40.99)R 14 4 906.68608 0.11573 0 0 0 0 0 0 0 0 1607 1125 1647 1647 6483 7416 65466 40131 Mix4_TiO2_Reinj_1_1 7133 65466 40131 Mix4_TiO2_Reinj_1_1 7133 Q6ZNJ1;Q6ZNJ1-2 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 0.999996 53.6213 0 0 0 0 0.999996 53.6213 1.81096E-26 168.92 0 0 0 0 1 S ATDEAGSPLAAAA Proline-directed 0.05 1.81096E-26 168.92 _VLNTSSLESATDEAGpSPLAAAAAAAAAER_ VLNTSSLESATDEAGS(1)PLAAAAAAAAAER VLNT(-86.02)S(-84.97)S(-77.63)LES(-69.87)AT(-53.62)DEAGS(53.62)PLAAAAAAAAAER 16 3 932.44135 -0.11631 358760 0 0 0 358760 0 0 0 1608 1126 586 586 3166 3594 30036 18688 Mix4_TiO2_Reinj_1_5 1911 30036 18688 Mix4_TiO2_Reinj_1_5 1911 Q6ZRI6;Q6ZRI6-2 Q6ZRI6 Q6ZRI6 >sp|Q6ZRI6|CO039_HUMAN Uncharacterized protein C15orf39 OS=Homo sapiens GN=C15orf39 PE=1 SV=3;>sp|Q6ZRI6-2|CO039_HUMAN Isoform 2 of Uncharacterized protein C15orf39 OS=Homo sapiens GN=C15orf39 0.999995 53.3996 0 0 0.999995 53.3996 0.00518131 65.877 1 S KPTAEASPVKASR CDK1;CDK2;CK1;Proline-directed 0.0057 0.00518131 65.877 _KPTAEApSPVK_ KPTAEAS(1)PVK KPT(-53.4)AEAS(53.4)PVK 7 2 554.27592 0.2665 178140 0 0 0 178140 0 0 0 1609 1127 578 578 1064 1197 10002 6100 Mix4_TiO2_Reinj_1_5 6384 10002 6100 Mix4_TiO2_Reinj_1_5 6384 Q6ZRP7 Q6ZRP7 Q6ZRP7 >sp|Q6ZRP7|QSOX2_HUMAN Sulfhydryl oxidase 2 OS=Homo sapiens GN=QSOX2 PE=1 SV=3 0.995948 23.9061 0 0 0.995948 23.9061 1.66357E-46 229.52 1 S SADQGDSSEGGTL 1.66357E-46 229.52 _DNLLDTYSADQGDpSSEGGTLAR_ DNLLDTYSADQGDS(0.996)S(0.004)EGGTLAR DNLLDT(-146.52)Y(-164.53)S(-97.65)ADQGDS(23.91)S(-23.91)EGGT(-68.59)LAR 14 2 1182.995 0.49164 1544200 1.9205 0 0 0 1544200 0 0 0 1610 1129 195 195 6699 7671 67988 41731 Mix4_TiO2_Reinj_1_5 1213 67987 41730 Mix4_TiO2_1_5 886 Q6ZRY4 Q6ZRY4 Q6ZRY4 >sp|Q6ZRY4|RBPS2_HUMAN RNA-binding protein with multiple splicing 2 OS=Homo sapiens GN=RBPMS2 PE=2 SV=1 0.248408 0 0.0198716 -15.4939 0.0777033 44.817 0.248408 0 0.456807 19.795 1 S QVRWYPSSDTTQQ 0.0777033 44.817 _WpYPSSDTTQQGWK_ WY(0.248)PS(0.248)S(0.248)DT(0.248)T(0.006)QQGWK WY(0)PS(0)S(0)DT(0)T(-15.91)QQGWK 4 2 832.34305 0.62549 0 0 0 0 0 0 0 0 1611 1129 196 196 6699 7671 67988 41731 Mix4_TiO2_Reinj_1_5 1213 67987 41730 Mix4_TiO2_1_5 886 Q6ZRY4 Q6ZRY4 Q6ZRY4 >sp|Q6ZRY4|RBPS2_HUMAN RNA-binding protein with multiple splicing 2 OS=Homo sapiens GN=RBPMS2 PE=2 SV=1 0.248408 0 0.0756443 -9.68845 0.0777033 44.817 0.248408 0 0.456807 19.795 1 S VRWYPSSDTTQQG 0.0777033 44.817 _WpYPSSDTTQQGWK_ WY(0.248)PS(0.248)S(0.248)DT(0.248)T(0.006)QQGWK WY(0)PS(0)S(0)DT(0)T(-15.91)QQGWK 5 2 832.34305 0.62549 0 0 0 0 0 0 0 0 1612 1130 349 349 2071 2346 18994 11571 Mix4_TiO2_Reinj_1_5 5477 18994 11571 Mix4_TiO2_Reinj_1_5 5477 Q6ZS17;Q6ZS17-2 Q6ZS17 Q6ZS17 >sp|Q6ZS17|FA65A_HUMAN Protein FAM65A OS=Homo sapiens GN=FAM65A PE=1 SV=1;>sp|Q6ZS17-2|FA65A_HUMAN Isoform 2 of Protein FAM65A OS=Homo sapiens GN=FAM65A 0.689115 3.49162 0.1834 -5.13646 0.010761 72.686 0.689115 3.49162 0.00269598 81.185 0.497564 3.01167 0.118452 43.426 0 0 1 S KRFSTYSQSPPDT CK1 0.081 0.00269598 81.185 _FSTYpSQSPPDTPSLR_ FSTYS(0.689)QS(0.308)PPDT(0.002)PSLR FS(-37.71)T(-37.71)Y(-56.45)S(3.49)QS(-3.49)PPDT(-24.88)PS(-67.49)LR 5 2 881.88782 0.4683 402580 0 0 0 402580 0 0 0 1613 1130 351 351 2071 2346 18993 11570 Mix4_TiO2_1_5 4729 18994 11571 Mix4_TiO2_Reinj_1_5 5477 Q6ZS17;Q6ZS17-2 Q6ZS17 Q6ZS17 >sp|Q6ZS17|FA65A_HUMAN Protein FAM65A OS=Homo sapiens GN=FAM65A PE=1 SV=1;>sp|Q6ZS17-2|FA65A_HUMAN Isoform 2 of Protein FAM65A OS=Homo sapiens GN=FAM65A 0.598475 4.54442 0.598475 4.54442 0.010761 72.686 0.308411 -3.49162 0.00269598 81.185 0.248704 -3.01167 0.118452 43.426 0 0 1 S FSTYSQSPPDTPS CK1;CK2;Proline-directed 0.05 0.00269598 81.185 _FSTYSQpSPPDTPSLR_ FS(0.007)T(0.001)YS(0.183)QS(0.598)PPDT(0.21)PSLR FS(-19.33)T(-28.01)Y(-57.53)S(-5.14)QS(4.54)PPDT(-4.54)PS(-48.37)LR 7 2 881.88782 0.93188 88150 88150 0 0 0 0 0 0 1614 1132 294 294 2685 3058 25229 15583 Mix4_InSol_Tio2_Reinj_1 5547 25238 15592 Mix4_TiO2_Reinj_1_5 5211 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 0.999899 39.9517 0.928972 11.2691 4.86954E-26 183.16 0 0 0.99904 30.175 1.04173E-38 215.07 0.999086 30.3861 9.83999E-22 172.26 0.999899 39.9517 2.59372E-22 174.98 1 S KYSRHYSPEDEPS CAMK2;CK1;CK2;Proline-directed 0.042 1.04173E-38 215.07 _HYpSPEDEPSPEAQPIAAYK_ HYS(1)PEDEPSPEAQPIAAYK HY(-39.95)S(39.95)PEDEPS(-85.37)PEAQPIAAY(-174.98)K 3 2 1104.9779 -0.048175 2376900 461810 0 0 1677500 0 143000 94582 1615 1132 300 300 2685 3058 25236 15590 Mix4_TiO2_Reinj_1_5 5066 25238 15592 Mix4_TiO2_Reinj_1_5 5211 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 1 102.255 1 89.8201 4.86954E-26 183.16 0 0 1 102.255 1.04173E-38 215.07 1 100.185 9.83999E-22 172.26 1 104.045 2.59372E-22 174.98 1 S SPEDEPSPEAQPI Proline-directed 0.05 1.04173E-38 215.07 _HYSPEDEPpSPEAQPIAAYK_ HYSPEDEPS(1)PEAQPIAAYK HY(-147.38)S(-117.39)PEDEPS(102.25)PEAQPIAAY(-102.25)K 9 2 1104.9779 0.69125 2652900 557580 0 0 1306400 0 478020 310900 1616 1132 175 175 3094 3516;3517 29407 18336 Mix4_TiO2_Reinj_1_5 7703 29407 18336 Mix4_TiO2_Reinj_1_5 7703 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 0.986723 19.2856 0.648586 4.37618 0.0356471 76.395 0.986723 19.2856 1.64663E-11 121.06 1 S PFTKKKSMEELTV AURORA;AURORA-A;CK1;CK2 0.006142092 1.64663E-11 121.06 _KKpSM(ox)EELTVIQCTSQELPAQTGLLSQTGDVPLPAGR_ KKS(0.987)MEELT(0.012)VIQCT(0.001)S(0.001)QELPAQTGLLSQTGDVPLPAGR KKS(19.29)MEELT(-19.29)VIQCT(-30.79)S(-30.79)QELPAQT(-81.19)GLLS(-89.82)QT(-90.83)GDVPLPAGR 3 3 1326.9899 -0.40359 970330 166020 0 0 804310 0 0 0 1617 1132 186 186 3094 3516;3517 29406 18335 Mix4_TiO2_Reinj_1_5 7692 29407 18336 Mix4_TiO2_Reinj_1_5 7703 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 0.387013 0 0.0507758 -11.0631 0.0356471 76.395 0.387013 0 1.64663E-11 121.06 1 S TVIQCTSQELPAQ 1.64663E-11 121.06 _KKSM(ox)EELTVIQCpTSQELPAQTGLLSQTGDVPLPAGR_ KKS(0.109)MEELT(0.109)VIQCT(0.387)S(0.387)QELPAQT(0.007)GLLS(0.001)QTGDVPLPAGR KKS(-5.51)MEELT(-5.51)VIQCT(0)S(0)QELPAQT(-17.23)GLLS(-27.84)QT(-30.49)GDVPLPAGR 14 4 995.49426 0.34042 0 0 0 0 0 0 0 0 1618 1132 93 93 3442 3887 32457 20127 Mix4_TiO2_Reinj_2_1 4407 32456 20126 Mix4_TiO2_Reinj_1_5 6761 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 1 37.8843 1 50.0064 8.60297E-10 118.82 1 71.8614 4.03297E-10 128.66 1 164.89 5.15948E-21 164.89 1 37.8843 0.267946 37.884 1 93.6502 3.49603E-06 108.28 1 22.8487 4.99018E-10 126.6 1 S FAPPEVSPEQAKT Proline-directed 0.05 5.15948E-21 164.89 _LGGAVPFAPPEVpSPEQAK_ LGGAVPFAPPEVS(1)PEQAK LGGAVPFAPPEVS(37.88)PEQAK 13 2 937.45842 0.37264 23744000 4783300 760380 0 12169000 28544 2866500 3136500 1619 1132 67 67 4427 5036;5037 42124 25953 Mix4_TiO2_Reinj_1_5 4507 42123 25952 Mix4_TiO2_1_5 3842 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 1 78.7252 1 95.2477 2.14894E-06 108.56 1 78.7252 0.000704514 86.865 1 S RPLLMESEEEDES CK2;NEK6 0.076 2.14894E-06 108.56 _PLLM(ox)EpSEEEDESCRPPPGK_ PLLMES(1)EEEDESCRPPPGK PLLMES(78.73)EEEDES(-78.73)CRPPPGK 6 3 765.98849 -0.49271 1704000 457700 0 0 1246300 0 0 0 1620 1134 280 280 3261 3696 30847 19145 Mix4_TiO2_Reinj_1_3 1706 30847 19145 Mix4_TiO2_Reinj_1_3 1706 Q6ZT07 Q6ZT07 Q6ZT07 >sp|Q6ZT07|TBCD9_HUMAN TBC1 domain family member 9 OS=Homo sapiens GN=TBC1D9 PE=1 SV=2 1 33.9651 1 33.9651 0.0366277 33.965 1 S KSPKKVSALKRDL 0.0366277 33.965 _KVpSALK_ KVS(1)ALK KVS(33.97)ALK 3 2 363.2015 -1.1131 0 0 0 0 0 0 0 0 1621 1136 201 201 6641 7603 67378 41393 Mix4_InSol_TiO2_1 4421 67378 41393 Mix4_InSol_TiO2_1 4421 Q6ZUT6;Q6ZUT6-4;Q6ZUT6-3 Q6ZUT6 Q6ZUT6 >sp|Q6ZUT6|CO052_HUMAN Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52 PE=1 SV=1;>sp|Q6ZUT6-4|CO052_HUMAN Isoform 4 of Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52;>sp|Q6ZUT6-3|CO052_HUMAN Isoform 3 of Uncharacterized protein C 0.425177 0 0.181853 -6.28305 0.435509 31.973 0.272524 -2.21607 0.455068 31.341 0.425177 0 0.0292389 59.549 0.315624 -0.554305 0.803487 20.248 1 S GGRVTRSPPTQVA Proline-directed 0.05 0.0292389 59.549 _VTRpSPPTQVAISSDSAR_ VT(0.15)RS(0.425)PPT(0.425)QVAISSDSAR VT(-4.54)RS(0)PPT(0)QVAIS(-59.55)S(-59.55)DS(-59.55)AR 4 3 617.97019 0.60169 0 0 0 0 0 0 0 0 1622 1137 1114 1114 4944 5620 47547 29018 Mix4_TiO2_Reinj_1_5 6030 47546 29017 Mix4_TiO2_1_5 5210 Q6ZUT9-2;Q6ZUT9 Q6ZUT9-2 Q6ZUT9-2 >sp|Q6ZUT9-2|DEN5B_HUMAN Isoform 2 of DENN domain-containing protein 5B OS=Homo sapiens GN=DENND5B;>sp|Q6ZUT9|DEN5B_HUMAN DENN domain-containing protein 5B OS=Homo sapiens GN=DENND5B PE=1 SV=2 0.497792 0 0.451165 0 0.00448712 68.018 0.497792 0 0.210953 28.878 1 S RRLSITSLTGKNN CK1 0.081 0.00448712 68.018 _RLSIpTSLTGK_ RLS(0.003)IT(0.498)S(0.498)LT(0.001)GK RLS(-22.07)IT(0)S(0)LT(-25.75)GK 6 2 578.3103 0.12826 0 0 0 0 0 0 0 0 1623 1138 653 653 3615 4075 34025 21015 Mix4_TiO2_Reinj_1_6 3732 34025 21015 Mix4_TiO2_Reinj_1_6 3732 Q6ZW61 Q6ZW61 Q6ZW61 >sp|Q6ZW61|BBS12_HUMAN Bardet-Biedl syndrome 12 protein OS=Homo sapiens GN=BBS12 PE=1 SV=2 0.999961 44.9732 0.754515 7.88672 0.804538 7.8867 0.998328 30.77 0.255263 30.77 0.999961 44.9732 0.0530143 51.526 0 0 1 S IFNSDISNKLEQI CK1 0.081 0.0530143 51.526 _LNSRIFNSDIpSNK_ LNSRIFNSDIS(1)NK LNS(-51.53)RIFNS(-44.97)DIS(44.97)NK 11 2 794.37997 -0.54279 798930 22678 146820 0 629430 0 0 0 1624 1139 366 366 5177 5893 50137 30644 Mix4_TiO2_Reinj_1_6 2271 50136 30643 Mix4_TiO2_Reinj_1_1 2341 Q6ZWL3;Q6ZWL3-2 Q6ZWL3 Q6ZWL3 >sp|Q6ZWL3|CP4V2_HUMAN Cytochrome P450 4V2 OS=Homo sapiens GN=CYP4V2 PE=1 SV=2;>sp|Q6ZWL3-2|CP4V2_HUMAN Isoform 2 of Cytochrome P450 4V2 OS=Homo sapiens GN=CYP4V2 0.5 0 0 0 0.153658 -7.40991 0.1226 37.931 0.5 0 0.110249 38.931 0 0 1 S DDVFGKSDRPATV 0.110249 38.931 _pSDRPATVEDLKK_ S(0.5)DRPAT(0.5)VEDLKK S(0)DRPAT(0)VEDLKK 1 2 719.85051 -1.0397 427490 0 0 0 427490 0 0 0 1625 1141 3406 3406 1248 1404 11715 7191 Mix4_TiO2_Reinj_1_1 5378 11715 7191 Mix4_TiO2_Reinj_1_1 5378 Q70CQ2;Q70CQ2-2;Q70CQ2-3 Q70CQ2 Q70CQ2 >sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2;>sp|Q70CQ2-2|UBP34_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34;>sp|Q70CQ2-3|UBP34_HUMAN Isoform 3 of Ubiquitin carbo 0.999802 40.0491 0.992297 24.11 3.39505E-17 151.7 0 0 0.999802 40.0491 4.88693E-24 164.88 0 0 0 0 1 S TEQDLPSPENSSV GSK3;Proline-directed 0.05 4.88693E-24 164.88 _DSSIIDPGTEQDLPpSPENSSVK_ DSSIIDPGTEQDLPS(1)PENSSVK DS(-149.49)S(-143.54)IIDPGT(-71.66)EQDLPS(40.05)PENS(-40.05)S(-40.05)VK 15 2 1198.0311 -0.59435 762490 2.4406 193670 0 0 568820 0 0 0 1626 1141 3410 3410 1248 1404 11716 7192 Mix4_TiO2_Reinj_1_1 5404 11715 7191 Mix4_TiO2_Reinj_1_1 5378 Q70CQ2;Q70CQ2-2;Q70CQ2-3 Q70CQ2 Q70CQ2 >sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2;>sp|Q70CQ2-2|UBP34_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34;>sp|Q70CQ2-3|UBP34_HUMAN Isoform 3 of Ubiquitin carbo 0.402268 0 0.333333 0 3.39505E-17 151.7 0 0 0.402268 0 4.88693E-24 164.88 0 0 0 0 1 S LPSPENSSVKEYR CK1 0.143 4.88693E-24 164.88 _DSSIIDPGTEQDLPSPENpSSVK_ DSSIIDPGTEQDLPS(0.195)PENS(0.402)S(0.402)VK DS(-50.6)S(-50.6)IIDPGT(-38)EQDLPS(-3.14)PENS(0)S(0)VK 19 3 799.02313 -0.48353 0 0 0 0 0 0 0 0 0 1627 1141 3411 3411 1248 1404 11716 7192 Mix4_TiO2_Reinj_1_1 5404 11715 7191 Mix4_TiO2_Reinj_1_1 5378 Q70CQ2;Q70CQ2-2;Q70CQ2-3 Q70CQ2 Q70CQ2 >sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2;>sp|Q70CQ2-2|UBP34_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34;>sp|Q70CQ2-3|UBP34_HUMAN Isoform 3 of Ubiquitin carbo 0.402268 0 0.333333 0 3.39505E-17 151.7 0 0 0.402268 0 4.88693E-24 164.88 0 0 0 0 1 S PSPENSSVKEYRM CK2 0.117 4.88693E-24 164.88 _DSSIIDPGTEQDLPSPENpSSVK_ DSSIIDPGTEQDLPS(0.195)PENS(0.402)S(0.402)VK DS(-50.6)S(-50.6)IIDPGT(-38)EQDLPS(-3.14)PENS(0)S(0)VK 20 3 799.02313 -0.48353 0 0 0 0 0 0 0 0 0 1628 1141 2488 2488 2350 2659 21695 13280 Mix4_TiO2_2_1 5178 21695 13280 Mix4_TiO2_2_1 5178 Q70CQ2;Q70CQ2-2;Q70CQ2-3 Q70CQ2 Q70CQ2 >sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2;>sp|Q70CQ2-2|UBP34_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34;>sp|Q70CQ2-3|UBP34_HUMAN Isoform 3 of Ubiquitin carbo 1 104.308 1 97.3746 9.98065E-13 125.7 1 104.308 2.23068E-13 134.78 0 0 1 S PQVEVLSEEEGEE CK2 0.117 2.23068E-13 134.78 _GPENPQVEVLpSEEEGEEEEEEEDILSLAEEK_ GPENPQVEVLS(1)EEEGEEEEEEEDILSLAEEK GPENPQVEVLS(104.31)EEEGEEEEEEEDILS(-104.31)LAEEK 11 3 1198.847 -0.11368 800970 745560 55405 0 0 0 0 0 1629 1142 150 150 1327 1496 12416 7588 Mix4_TiO2_1_5 7934 12416 7588 Mix4_TiO2_1_5 7934 Q70J99-3;Q70J99;Q70J99-2 Q70J99-3 Q70J99-3 >sp|Q70J99-3|UN13D_HUMAN Isoform 3 of Protein unc-13 homolog D OS=Homo sapiens GN=UNC13D;>sp|Q70J99|UN13D_HUMAN Protein unc-13 homolog D OS=Homo sapiens GN=UNC13D PE=1 SV=1;>sp|Q70J99-2|UN13D_HUMAN Isoform 2 of Protein unc-13 homolog D OS=Homo sapiens GN=U 0.973756 15.6941 0.973756 15.6941 1.72806E-12 132.05 0.955805 13.3499 3.75467E-08 114.68 1 S VGVPGGSPGSRHR Proline-directed 0.05 1.72806E-12 132.05 _DVSGFSDPYCLLGIEQGVGVPGGpSPGSR_ DVSGFSDPYCLLGIEQGVGVPGGS(0.974)PGS(0.026)R DVS(-126.12)GFS(-107.48)DPY(-96.4)CLLGIEQGVGVPGGS(15.69)PGS(-15.69)R 24 3 963.10379 -0.42602 509930 284900 0 0 225040 0 0 0 1630 1142 153 153 1327 1496 12418 7590 Mix4_TiO2_Reinj_1_5 8618 12416 7588 Mix4_TiO2_1_5 7934 Q70J99-3;Q70J99;Q70J99-2 Q70J99-3 Q70J99-3 >sp|Q70J99-3|UN13D_HUMAN Isoform 3 of Protein unc-13 homolog D OS=Homo sapiens GN=UNC13D;>sp|Q70J99|UN13D_HUMAN Protein unc-13 homolog D OS=Homo sapiens GN=UNC13D PE=1 SV=1;>sp|Q70J99-2|UN13D_HUMAN Isoform 2 of Protein unc-13 homolog D OS=Homo sapiens GN=U 0.540723 0.709006 0.0262444 -15.6941 1.72806E-12 132.05 0.540723 0.709006 3.75467E-08 114.68 1 S PGGSPGSRHRQKA CK1 0.081 1.72806E-12 132.05 _DVSGFSDPYCLLGIEQGVGVPGGSPGpSR_ DVSGFSDPYCLLGIEQGVGVPGGS(0.459)PGS(0.541)R DVS(-83.84)GFS(-82.85)DPY(-78.41)CLLGIEQGVGVPGGS(-0.71)PGS(0.71)R 27 3 963.10379 -0.19999 847180 0 0 0 847180 0 0 0 1631 1143 923 923 3853 4362;4363 36525 22528 Mix4_TiO2_Reinj_1_1 5843 36525 22528 Mix4_TiO2_Reinj_1_1 5843 Q71F56 Q71F56 Q71F56 >sp|Q71F56|MD13L_HUMAN Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens GN=MED13L PE=1 SV=1 1 85.3281 0 0 0 0 1 85.3281 8.61338E-07 101.18 1 S VEDGLGSPKPEEI CDK1;Proline-directed 0.0057 8.61338E-07 101.18 _MEVEDGLGpSPKPEEIKDFSYVHK_ MEVEDGLGS(1)PKPEEIKDFSYVHK MEVEDGLGS(85.33)PKPEEIKDFS(-85.76)Y(-85.33)VHK 9 3 905.41883 0.074263 1088800 0 0 0 1088800 0 0 0 1632 1143 1081 1081 6714 7687 68119 41775 Mix4_TiO2_Reinj_1_1 2319 68119 41775 Mix4_TiO2_Reinj_1_1 2319 Q71F56 Q71F56 Q71F56 >sp|Q71F56|MD13L_HUMAN Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens GN=MED13L PE=1 SV=1 0.998989 30.9574 0.354924 0.946153 0.38577 33.582 0.998989 30.9574 0.0018278 81.415 0 0 0 0 1 S DSTDQGSPASTPS CK1;Proline-directed 0.05 0.0018278 81.415 _YDSTDQGpSPASTPSTTR_ YDSTDQGS(0.999)PAS(0.001)TPSTTR Y(-79.39)DS(-54.32)T(-39.99)DQGS(30.96)PAS(-30.96)T(-39.76)PS(-67.74)T(-74.21)T(-73.97)R 8 2 925.87564 -0.98174 32529 0 0 0 32529 0 0 0 1633 1144 600 600 538 612 5046 3041 Mix4_TiO2_Reinj_1_5 6188 5045 3040 Mix4_TiO2_1_5 5393 Q71RC2-4;Q71RC2;Q71RC2-3 Q71RC2-4 Q71RC2-4 >sp|Q71RC2-4|LARP4_HUMAN Isoform 4 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC2|LARP4_HUMAN La-related protein 4 OS=Homo sapiens GN=LARP4 PE=1 SV=3;>sp|Q71RC2-3|LARP4_HUMAN Isoform 3 of La-related protein 4 OS=Homo sapiens GN=LARP4 0.513595 1.46699 0.394261 0 2.60248E-07 112.99 0.513595 1.46699 0.123841 51.829 1 S TKPSRASTASPCN CK1;PKA 0.042 2.60248E-07 112.99 _ApSTASPCNNNINAATAVALQEPR_ AS(0.514)T(0.1)AS(0.366)PCNNNINAAT(0.02)AVALQEPR AS(1.47)T(-7.12)AS(-1.47)PCNNNINAAT(-14)AVALQEPR 2 3 817.37584 0.039185 331790 0 0 0 331790 0 0 0 1634 1144 603 603 538 612 5043 3038 Mix4_TiO2_1_3 5460 5045 3040 Mix4_TiO2_1_5 5393 Q71RC2-4;Q71RC2;Q71RC2-3 Q71RC2-4 Q71RC2-4 >sp|Q71RC2-4|LARP4_HUMAN Isoform 4 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC2|LARP4_HUMAN La-related protein 4 OS=Homo sapiens GN=LARP4 PE=1 SV=3;>sp|Q71RC2-3|LARP4_HUMAN Isoform 3 of La-related protein 4 OS=Homo sapiens GN=LARP4 0.547895 3.8626 0.547895 3.8626 2.60248E-07 112.99 0.366372 -1.46699 0.123841 51.829 1 S SRASTASPCNNNI CK1;Proline-directed 0.05 2.60248E-07 112.99 _ASTApSPCNNNINAATAVALQEPR_ AS(0.225)T(0.225)AS(0.548)PCNNNINAAT(0.002)AVALQEPR AS(-3.86)T(-3.86)AS(3.86)PCNNNINAAT(-24.74)AVALQEPR 5 3 817.37584 0.49893 88679 88679 0 0 0 0 0 0 1635 1144 589 589 875 986 8301 5008 Mix4_TiO2_Reinj_1_5 5330 8301 5008 Mix4_TiO2_Reinj_1_5 5330 Q71RC2-4;Q71RC2;Q71RC2-3;Q71RC2-2 Q71RC2-4 Q71RC2-4 >sp|Q71RC2-4|LARP4_HUMAN Isoform 4 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC2|LARP4_HUMAN La-related protein 4 OS=Homo sapiens GN=LARP4 PE=1 SV=3;>sp|Q71RC2-3|LARP4_HUMAN Isoform 3 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC 0.999725 36.5286 0.993002 24.8701 0.000110544 95.832 0 0 0.999725 36.5286 1.78906E-10 121.83 1 S QTTIPVSPPSTTK CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.78906E-10 121.83 _DGLNQTTIPVpSPPSTTKPSR_ DGLNQTTIPVS(1)PPSTTKPSR DGLNQT(-88.61)T(-81.5)IPVS(36.53)PPS(-50.61)T(-44.23)T(-36.53)KPS(-51.8)R 11 3 726.02637 0.052529 1390400 273650 0 0 1116800 0 0 0 1636 1144 728 728 1783 2013 16437 9921 Mix4_TiO2_Reinj_1_5 3043 16437 9921 Mix4_TiO2_Reinj_1_5 3043 Q71RC2-4;Q71RC2;Q71RC2-3;Q71RC2-2 Q71RC2-4 Q71RC2-4 >sp|Q71RC2-4|LARP4_HUMAN Isoform 4 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC2|LARP4_HUMAN La-related protein 4 OS=Homo sapiens GN=LARP4 PE=1 SV=3;>sp|Q71RC2-3|LARP4_HUMAN Isoform 3 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC 1 101.689 1 82.5292 0.000916848 82.529 1 101.689 0.00229527 101.69 1 S QYVPPRSPK____ CDK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00229527 101.69 _EQYVPPRpSPK_ EQYVPPRS(1)PK EQY(-101.69)VPPRS(101.69)PK 8 2 640.80538 0.15221 365600 82556 0 0 283040 0 0 0 1637 1146 660 660 625;2979 720;3388 5951 3486 Mix4_InSol_Tio2_Reinj_1 1730 28375 17615 Mix4_TiO2_Reinj_1_5 1414 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 0.976875 17.8061 0 0 0 0 0.539346 5.45613 0.00260306 84.491 0.780381 6.40414 0.0682922 43.21 0.976875 17.8061 0.0106577 60.802 1 S QDRKAVSPSSSEK GSK3;Proline-directed 0.05 0.00260306 84.491 _AVpSPSSSEKR_ AVS(0.977)PS(0.016)S(0.003)S(0.003)EKR AVS(17.81)PS(-17.81)S(-24.5)S(-24.5)EKR 3 2 564.25826 -0.10351 414100 0 0 0 147570 0 127060 139470 1638 1146 662 662 625;2979 720;3388 28374 17614 Mix4_TiO2_Reinj_1_1 1130 28375 17615 Mix4_TiO2_Reinj_1_5 1414 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 0.333245 0 0 0 0 0 0.333245 0 0.00260306 84.491 0.135004 -7.53866 0.0682922 43.21 0.0166184 -17.3391 0.0106577 60.802 1 S RKAVSPSSSEKRS CK2 0.117 0.00260306 84.491 _KAVSPpSSSEKR_ KAVSPS(0.333)S(0.333)S(0.333)EKR KAVS(-30.97)PS(0)S(0)S(0)EKR 6 2 628.30574 0.69475 0 0 0 0 0 0 0 0 1639 1146 663 663 625;2979 720;3388 28373 17613 Mix4_InSol_Tio2_Reinj_1 1692 28375 17615 Mix4_TiO2_Reinj_1_5 1414 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 0.900538 10.4236 0 0 0 0 0.763026 6.47605 0.00260306 84.491 0.765972 7.53866 0.0682922 43.21 0.900538 10.4236 0.0106577 60.802 1 S KAVSPSSSEKRSK CK1 0.081 0.00260306 84.491 _KAVSPSpSSEKR_ KAVS(0.001)PS(0.017)S(0.901)S(0.082)EKR KAVS(-28.9)PS(-17.34)S(10.42)S(-10.42)EKR 7 2 628.30574 0.78747 378820 0 0 0 142240 0 124460 112120 1640 1146 664 664 625;2979 720;3388 28374 17614 Mix4_TiO2_Reinj_1_1 1130 28375 17615 Mix4_TiO2_Reinj_1_5 1414 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 0.333245 0 0 0 0 0 0.333245 0 0.00260306 84.491 0.178605 -6.40414 0.0682922 43.21 0.0816845 -10.4236 0.0106577 60.802 1 S AVSPSSSEKRSKN CK1;GSK3 0.081 0.00260306 84.491 _KAVSPpSSSEKR_ KAVSPS(0.333)S(0.333)S(0.333)EKR KAVS(-30.97)PS(0)S(0)S(0)EKR 8 2 628.30574 0.69475 0 0 0 0 0 0 0 0 1641 1146 890 890 2014 2282 18487 11204 Mix4_TiO2_1_5 4283 18487 11204 Mix4_TiO2_1_5 4283 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 1 150.259 1 150.259 1.25096E-12 150.26 2 S RFLETDSEEEQEE CK2 0.117 1.25096E-12 150.26 _FLEpTDpSEEEQEEVNEK_ FLET(1)DS(1)EEEQEEVNEK FLET(150.26)DS(150.26)EEEQEEVNEK 6 2 1057.89 0.10441 54166 54166 0 0 0 0 0 0 1642 1146 1098 1098 4324 4917 41076 25268 Mix4_TiO2_Reinj_1_5 4923 41074 25266 Mix4_TiO2_1_5 4047 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 0.763681 5.09416 0.7624 5.06339 0.0152155 63.811 0 0 0.763681 5.09416 0.0205219 59.293 0 0 0 0 1 S ETDHRNSSPGEAS PKA 0.042 0.0152155 63.811 _NpSSPGEASLLEK_ NS(0.764)S(0.236)PGEASLLEK NS(5.09)S(-5.09)PGEAS(-56.2)LLEK 2 2 656.29504 0.065766 341680 73819 0 0 267860 0 0 0 1643 1146 1099 1099 4324 4917 41075 25267 Mix4_TiO2_Reinj_1_1 4379 41074 25266 Mix4_TiO2_1_5 4047 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 0.886689 8.94757 0.821157 7.22654 0.0152155 63.811 0 0 0.886689 8.94757 0.0205219 59.293 0 0 0 0 1 S TDHRNSSPGEASL CAMK2;CK2;Polo box;Proline-directed 0.00405 0.0152155 63.811 _NSpSPGEASLLEK_ NS(0.113)S(0.887)PGEASLLEK NS(-8.95)S(8.95)PGEAS(-34.32)LLEK 3 2 656.29504 0.43576 117210 16818 0 0 100390 0 0 0 1644 1147;1148;1149 448;414;414 414 536;2974 609;3382;3383 28327 17591 Mix4_InSol_TiO2_1 5759 28327 17591 Mix4_InSol_TiO2_1 5759 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.840396 7.40824 0 0 0 0 0.840396 7.40824 0.00546868 76.095 0.800302 7.11609 0.155064 42.207 2 S ESGRKASSTAKVP CAMK2;PKA 0.004788 0.00546868 76.095 _KApSSTAKVPApSPLPGLER_ KAS(0.84)S(0.153)T(0.007)AKVPAS(1)PLPGLER KAS(7.41)S(-7.41)T(-20.81)AKVPAS(76.1)PLPGLER 3 3 656.99003 -0.20726 573190 0 0 0 0 0 361500 211680 1645 1147;1148;1149 456;422;422 422 536;2974;6522 609;3382;3383;7462 65894 40413 Mix4_TiO2_Reinj_1_5 5626 28319 17587 Mix4_InSol_TiO2_1 5546 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 1 85.7461 1 105.868 0.00206561 105.87 1 37.5178 0.00288279 81.377 1 85.7461 0.00233175 108.38 0 0 1 35.6166 7.64845E-10 120.88 1 34.0638 0.0018572 92.793 1 S TAKVPASPLPGLE ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 7.64845E-10 120.88 _VPApSPLPGLER_ VPAS(1)PLPGLER VPAS(85.75)PLPGLER 4 2 608.3103 0.063605 34933000 6217800 3393900 0 18222000 0 3847600 3251400 1646 1147;1149 514;480 480 537 610;611 5036 3033 Mix4_TiO2_1_3 2892 5036 3033 Mix4_TiO2_1_3 2892 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-14 Q7KZI7;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.991821 20.838 0.991821 20.838 1.01763E-05 117.36 0.985383 18.2878 0.000223501 98.892 1 S MPGSRASTASASA CK1;PKA 0.042 1.01763E-05 117.36 _ApSTASASAAVSAAR_ AS(0.992)T(0.008)ASASAAVSAAR AS(20.84)T(-20.84)AS(-59.23)AS(-88.1)AAVS(-117.36)AAR 2 2 650.79828 0.18436 378940 75614 0 0 303330 0 0 0 1647 1147;1149 517;483 483 537 610;611 5041 3037 Mix4_TiO2_Reinj_1_3 3502 5041 3037 Mix4_TiO2_Reinj_1_3 3502 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-14 Q7KZI7;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.973301 13.3446 1.18519E-06 -59.2265 1.01763E-05 117.36 0.973301 13.3446 0.0615773 51.257 2 S SRASTASASAAVS CK1 0.081 0.0615773 51.257 _ASpTApSASAAVSAAR_ AS(0.433)T(0.593)AS(0.973)AS(0.001)AAVSAAR AS(-1.44)T(1.44)AS(13.34)AS(-33.13)AAVS(-51.26)AAR 5 2 690.78145 -0.22383 70424 0 0 0 70424 0 0 0 1648 1147;1148;1149 619;531;585 585 1146;1147 1288;1290 10752 6614 Mix4_InSol_TiO2_2 3850 10758 6622 Mix4_TiO2_1_3 4154 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.952539 15.8746 0.930403 11.827 4.88078E-17 152.45 0.932645 12.6725 3.25381E-11 129.41 0.952539 15.8746 1.94992E-16 139.79 0.916122 13.6468 1.15669E-09 118.09 1 S YGVTPASPSGHSQ ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.88078E-17 152.45 _DQQNLPYGVTPApSPSGHSQGR_ DQQNLPY(0.001)GVT(0.025)PAS(0.953)PS(0.022)GHSQGR DQQNLPY(-31.24)GVT(-15.87)PAS(15.87)PS(-16.38)GHS(-37.46)QGR 13 2 1138.5082 -0.25706 16052000 12.489 3969800 0 0 10207000 0 332190 1542900 1649 1147;1148;1149 621;533;587 587 1146;1147 1288;1290 10754 6617 Mix4_InSol_Tio2_Reinj_1 5041 10758 6622 Mix4_TiO2_1_3 4154 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.901232 9.60608 0.438823 -0.409255 4.88078E-17 152.45 0.355478 -2.57096 3.25381E-11 129.41 0.56927 1.29988 1.94992E-16 139.79 0.901232 9.60608 1.15669E-09 118.09 1 S VTPASPSGHSQGR 4.88078E-17 152.45 _DQQNLPYGVTPASPpSGHSQGR_ DQQNLPYGVTPAS(0.099)PS(0.901)GHSQGR DQQNLPY(-88.57)GVT(-42.65)PAS(-9.61)PS(9.61)GHS(-43.57)QGR 15 2 1138.5082 -0.22382 595150 0.46305 0 0 0 0 0 307690 287460 1650 1147;1148;1149 624;536;590 590 1146;1147 1288;1290 10749 6609 Mix4_InSol_TiO2_1 5091 10758 6622 Mix4_TiO2_1_3 4154 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.767622 7.55053 0.482186 0.409255 4.88078E-17 152.45 0.758005 7.98113 3.25381E-11 129.41 0.767622 7.55053 1.94992E-16 139.79 0.200259 -4.8642 1.15669E-09 118.09 1 S ASPSGHSQGRRGA CK1 0.081 4.88078E-17 152.45 _DQQNLPYGVTPASPSGHpSQGR_ DQQNLPYGVTPAS(0.135)PS(0.097)GHS(0.768)QGR DQQNLPY(-99.96)GVT(-36.18)PAS(-7.55)PS(-8.97)GHS(7.55)QGR 18 3 759.34124 -0.50271 1571100 1.2224 0 0 0 76121 0 1495000 0 1651 1147 26 26 1270 1433 11958 7341 Mix4_TiO2_Reinj_1_3 4206 11959 7342 Mix4_TiO2_Reinj_1_3 4228 Q7KZI7;Q7KZI7-8;Q7KZI7-11 Q7KZI7 Q7KZI7 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.462867 0 0.447332 0 0.118283 46.621 0 0 0.462867 0 0.000841668 90.837 1 S TLGHLDSKPSSKS GSK3 0.081 0.000841668 90.837 _DTEQPTLGHLDpSKPSSK_ DTEQPT(0.018)LGHLDS(0.463)KPS(0.463)S(0.056)K DT(-46.62)EQPT(-14.05)LGHLDS(0)KPS(0)S(-9.17)K 12 3 640.62973 -0.064755 0 0 0 0 0 0 0 0 0 1652 1147 29 29 1270 1433 11958 7341 Mix4_TiO2_Reinj_1_3 4206 11959 7342 Mix4_TiO2_Reinj_1_3 4228 Q7KZI7;Q7KZI7-8;Q7KZI7-11 Q7KZI7 Q7KZI7 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.462867 0 0.447332 0 0.118283 46.621 0 0 0.462867 0 0.000841668 90.837 1 S HLDSKPSSKSNMI CK1 0.081 0.000841668 90.837 _DTEQPTLGHLDpSKPSSK_ DTEQPT(0.018)LGHLDS(0.463)KPS(0.463)S(0.056)K DT(-46.62)EQPT(-14.05)LGHLDS(0)KPS(0)S(-9.17)K 15 3 640.62973 -0.064755 0 0 0 0 0 0 0 0 0 1653 1147 30 30 1270 1433 11959 7342 Mix4_TiO2_Reinj_1_3 4228 11959 7342 Mix4_TiO2_Reinj_1_3 4228 Q7KZI7;Q7KZI7-8;Q7KZI7-11 Q7KZI7 Q7KZI7 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.814804 6.50818 0.0541716 -9.16858 0.118283 46.621 0 0 0.814804 6.50818 0.000841668 90.837 1 S LDSKPSSKSNMIR CK1 0.143 0.000841668 90.837 _DTEQPTLGHLDSKPSpSK_ DTEQPTLGHLDS(0.003)KPS(0.182)S(0.815)K DT(-90.84)EQPT(-78.66)LGHLDS(-24.16)KPS(-6.51)S(6.51)K 16 2 960.44095 -0.2842 94574 0.32215 0 0 0 94574 0 0 0 1654 1147;1148;1149 631;543;597 597 2117;4878 2401;5548 19535 11912 Mix4_InSol_TiO2_1 5144 46844 28672 Mix4_TiO2_Reinj_1_5 4435 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.999551 34.2869 0.994769 22.7916 0.00437818 70.225 0.996755 25.437 0.000939717 82.962 0 0 0.999551 34.2869 0.00109237 78.487 0.996597 24.6669 0.00431952 68.535 1 S QGRRGASGSIFSK CAMK2 0.042 0.000939717 82.962 _GApSGSIFSK_ GAS(1)GSIFSK GAS(34.29)GS(-34.29)IFS(-41.17)K 3 2 467.20751 -0.24143 5859000 604250 0 0 3685900 0 785500 783390 1655 1147;1148;1149 633;545;599 599 2117;4878 2401;5548 19538 11917 Mix4_TiO2_Reinj_1_3 4424 46844 28672 Mix4_TiO2_Reinj_1_5 4435 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.999233 31.254 0.0978432 -9.64751 0.00437818 70.225 0.999233 31.254 0.000939717 82.962 0 0 0.117506 -8.75651 0.00109237 78.487 0.105522 -9.28225 0.00431952 68.535 1 S RRGASGSIFSKFT 0.000939717 82.962 _GASGpSIFSK_ GASGS(0.999)IFS(0.001)K GAS(-47.44)GS(31.25)IFS(-31.25)K 5 2 467.20751 -0.049472 63938 0 0 0 63938 0 0 0 1656 1147;1148;1149 40;7;7 7 2413;4294 2734;4885 22553 14082 Mix4_TiO2_Reinj_1_3 3992 22552 14081 Mix4_TiO2_Reinj_1_3 3990 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.997177 26.2119 0.868418 8.8531 0.00918167 73.864 0.997177 26.2119 4.38634E-06 105.81 0.956036 14.0156 0.00139121 81.921 0.947808 13.1346 0.0110355 71.209 1 S MIRGRNSATSADE PKA 0.042 4.38634E-06 105.81 _GRNpSATSADEQPHIGNYR_ GRNS(0.997)AT(0.002)SADEQPHIGNYR GRNS(26.21)AT(-26.21)S(-33.57)ADEQPHIGNY(-96.11)R 4 2 1026.9478 0.011492 3805000 41.977 201410 0 0 3109100 0 290310 204210 1657 1147;1148;1149 43;10;10 10 2413;4294 2734;4885 40841 25130 Mix4_TiO2_Reinj_1_3 4313 22552 14081 Mix4_TiO2_Reinj_1_3 3990 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.996657 27.0239 0.983921 21.6588 0.00918167 73.864 0.996657 27.0239 4.38634E-06 105.81 0.387294 2.77909 0.00139121 81.921 0.0584947 -9.0552 0.0110355 71.209 1 S GRNSATSADEQPH CK1;CK2 0.081 4.38634E-06 105.81 _NSATpSADEQPHIGNYR_ NSAT(0.002)S(0.997)ADEQPHIGNY(0.001)R NS(-43.66)AT(-27.02)S(27.02)ADEQPHIGNY(-28.77)R 5 3 613.92677 0.22663 337510 3.7235 136890 0 0 200630 0 0 0 1658 1147;1148;1149 212;179;179 179 2689;3362 3062;3803 31688 19611 Mix4_TiO2_Reinj_1_4 7848 31677 19590 Mix4_TiO2_1_3 7130 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.597975 1.72431 0.563853 1.13282 5.47474E-32 209.73 0.000137035 -38.6311 0.000479152 90.715 0.597975 1.72431 7.64911E-26 176.24 0.0112979 -19.1932 0.229126 58.143 2.9914E-07 -65.2413 1.35075E-10 132.64 8.35275E-06 -50.7817 0.00016147 96.142 1 S LDTFCGSPPYAAP CK1;Proline-directed 0.05 5.47474E-32 209.73 _LDTFCGpSPPYAAPELFQGK_ LDT(0.402)FCGS(0.598)PPYAAPELFQGK LDT(-1.72)FCGS(1.72)PPY(-55.7)AAPELFQGK 7 3 726.65863 0.08234 1161500 154370 0 0 1007100 0 0 0 1659 1147;1148;1149 471;437;437 437 3097;6262 3520;7153 29458 18366 Mix4_TiO2_Reinj_1_3 3970 62356 37944 Mix4_TiO2_Reinj_1_3 4472 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.751951 8.07809 0.618183 6.70839 2.32057E-20 184.57 0 0 0.751951 8.07809 1.40651E-20 188.76 0.000546862 -29.5231 1.01117E-16 172.1 0.098915 -0.452006 9.32357E-13 146.09 1 S KTTPTPSTNSVLS CK1 0.143 1.40651E-20 188.76 _KKTTPTPpSTNSVLSTSTNR_ KKTTPT(0.117)PS(0.752)T(0.117)NS(0.014)VLSTSTNR KKT(-50.46)T(-34.25)PT(-8.08)PS(8.08)T(-8.08)NS(-17.42)VLS(-48.16)T(-48.16)S(-63.93)T(-71.04)NR 8 2 1050.5203 0.12637 347080 98033 0 0 249050 0 0 0 1660 1147;1148;1149 479;445;445 445 3097;6262 3520;7153 62354 37942 Mix4_TiO2_1_3 3749 62356 37944 Mix4_TiO2_Reinj_1_3 4472 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.872754 8.4547 0.872754 8.4547 2.32057E-20 184.57 0 0 0.398877 -1.77801 1.40651E-20 188.76 0.385766 -1.95754 1.01117E-16 172.1 0.850608 8.10743 9.32357E-13 146.09 1 S NSVLSTSTNRSRN GSK3;NEK6 0.076 1.40651E-20 188.76 _TTPTPSTNSVLSTpSTNR_ TTPTPSTNSVLST(0.003)S(0.873)T(0.125)NR T(-184.57)T(-180.62)PT(-153.94)PS(-108.54)T(-93.49)NS(-87.4)VLS(-46.93)T(-25.17)S(8.45)T(-8.45)NR 14 2 922.4253 -0.70312 672930 483350 0 0 0 0 0 189580 1661 1147;1148;1149 390;357;357 357 4436;4437;5698 5046;5047;6491 42198 25987 Mix4_TiO2_1_5 2505 42201 25990 Mix4_TiO2_Reinj_1_3 3034 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.935257 11.5975 0.935257 11.5975 1.01535E-08 123.91 0.743574 4.79883 0.54606 27.073 0.93481 12.1641 1.11684E-12 150.94 0 0 0.926024 14.0067 0.034985 64.11 0.81803 8.04016 0.0162928 64.412 1 S TNSSAPSPSHKVQ CK1;Proline-directed 0.05 1.11684E-12 150.94 _PSADLTNSSAPpSPSHK_ PSADLTNSSAPS(0.935)PS(0.065)HK PS(-65.14)ADLT(-65.14)NS(-65.14)S(-60.38)APS(11.6)PS(-11.6)HK 12 3 559.24896 0.4807 9259700 3161100 13481 0 5429800 0 547100 108230 1662 1147;1148;1149 392;359;359 359 4436;4437;5698 5046;5047;6491 42200 25989 Mix4_TiO2_Reinj_1_3 3018 42201 25990 Mix4_TiO2_Reinj_1_3 3034 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.916877 10.4259 0.782951 5.57409 1.01535E-08 123.91 0.246287 -4.79883 0.54606 27.073 0.916877 10.4259 1.11684E-12 150.94 0 0 0.0425825 -10.7774 0.034985 64.11 0.0814549 -6.23484 0.0162928 64.412 1 S SSAPSPSHKVQRS 1.11684E-12 150.94 _PSADLTNSSAPSPpSHK_ PSADLTNSSAPS(0.083)PS(0.917)HK PS(-118.32)ADLT(-118.32)NS(-111.13)S(-98.09)APS(-10.43)PS(10.43)HK 14 3 559.24896 0.19315 4275200 171120 0 0 4104100 0 0 0 1663 1147;1148;1149 486;452;452 452 5671 6458 55533 34006 Mix4_InSol_Tio2_Reinj_1 3965 55533 34006 Mix4_InSol_Tio2_Reinj_1 3965 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.999999 59.1026 0.999996 54.3569 0.000694765 79.432 0.999873 38.9469 0.097376 38.947 0.999997 55.103 0.00215617 75.779 0.971812 15.3751 0.5273 15.375 0.999991 50.5052 0.00223178 97.693 0.999999 59.1026 0.00289662 103.57 1 S TNRSRNSPLLERA CK1;PKA;Proline-directed 0.042 0.00289662 103.57 _SRNpSPLLER_ SRNS(1)PLLER S(-59.1)RNS(59.1)PLLER 4 2 576.28207 -0.32797 61958000 6443000 22269 0 42596000 25370 7434900 5436500 1664 1147;1149 569;535 535 6545;6546 7488;7489 66093 40576 Mix4_TiO2_Reinj_1_3 3789 66086 40569 Mix4_TiO2_1_5 3327 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-14 Q7KZI7;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.983837 17.8441 0.86897 8.21668 7.52626E-33 212.18 0.349291 -0.619172 1.54728 7.6113 0.983837 17.8441 1.216E-21 160 0 0 0.162659 -3.32 9.73266E-08 117.11 0.438161 -1.06862 2.13386E-10 118.81 1 S QRVPVASPSAHNI ERK/MAPK;Proline-directed 0.0034 7.52626E-33 212.18 _VPVApSPSAHNISSSGGAPDR_ VPVAS(0.984)PS(0.016)AHNISSSGGAPDR VPVAS(17.84)PS(-17.84)AHNIS(-70.34)S(-75.98)S(-69.53)GGAPDR 5 3 662.64074 -0.13634 14082000 184790 0 0 13897000 0 0 0 1665 1147;1149 571;537 537 6545;6546 7488;7489 66086 40569 Mix4_TiO2_1_5 3327 66086 40569 Mix4_TiO2_1_5 3327 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-14 Q7KZI7;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.999997 56.1727 0.999997 56.1727 7.52626E-33 212.18 0.584808 7.40758 1.54728 7.6113 0.999972 45.7226 1.216E-21 160 0 0 0.996325 25.9711 9.73266E-08 117.11 0.994997 23.0524 2.13386E-10 118.81 1 S VPVASPSAHNISS 7.52626E-33 212.18 _VPVASPpSAHNISSSGGAPDR_ VPVASPS(1)AHNISSSGGAPDR VPVAS(-56.17)PS(56.17)AHNIS(-61.4)S(-79.16)S(-102.88)GGAPDR 7 2 993.45747 -0.040954 21259000 8670300 15275 0 10595000 0 1252100 726410 1666 1148 481 481 1255;6545;6546 1415;7488;7489 66093 40576 Mix4_TiO2_Reinj_1_3 3789 66086 40569 Mix4_TiO2_1_5 3327 Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10 Q7KZI7-13 Q7KZI7-13 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-2|MARK2_HUMAN Isoform 2 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-7|MARK2_HUMAN Isoform 7 of Serine/threoni 0.983837 17.8441 0.86897 8.21668 7.52626E-33 212.18 0.349291 -0.619172 1.54728 7.6113 0.983837 17.8441 1.216E-21 160 0 0 0.162659 -3.32 9.73266E-08 117.11 0.438161 -1.06862 2.13386E-10 118.81 1 S QRVPVASPSAHNI ERK/MAPK;Proline-directed 0.0034 7.52626E-33 212.18 _VPVApSPSAHNISSSGGAPDR_ VPVAS(0.984)PS(0.016)AHNISSSGGAPDR VPVAS(17.84)PS(-17.84)AHNIS(-70.34)S(-75.98)S(-69.53)GGAPDR 5 3 662.64074 -0.13634 14082000 184790 0 0 13897000 0 0 0 1667 1148 483 483 1255;6545;6546 1415;7488;7489 66086 40569 Mix4_TiO2_1_5 3327 66086 40569 Mix4_TiO2_1_5 3327 Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10 Q7KZI7-13 Q7KZI7-13 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-2|MARK2_HUMAN Isoform 2 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-7|MARK2_HUMAN Isoform 7 of Serine/threoni 0.999997 56.1727 0.999997 56.1727 7.52626E-33 212.18 0.584808 7.40758 1.54728 7.6113 0.999972 45.7226 1.216E-21 160 0 0 0.996325 25.9711 9.73266E-08 117.11 0.994997 23.0524 2.13386E-10 118.81 1 S VPVASPSAHNISS 7.52626E-33 212.18 _VPVASPpSAHNISSSGGAPDR_ VPVASPS(1)AHNISSSGGAPDR VPVAS(-56.17)PS(56.17)AHNIS(-61.4)S(-79.16)S(-102.88)GGAPDR 7 2 993.45747 -0.040954 21376000 8670300 15275 0 10595000 0 1369200 726410 1668 1148 488 488 1255;6545;6546 1415;7488;7489 11836 7256 Mix4_InSol_Tio2_Reinj_1 4555 66086 40569 Mix4_TiO2_1_5 3327 Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10 Q7KZI7-13 Q7KZI7-13 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-2|MARK2_HUMAN Isoform 2 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-7|MARK2_HUMAN Isoform 7 of Serine/threoni 0.540055 2.51783 0.0808433 -8.9919 7.52626E-33 212.18 0.106232 -7.40758 1.54728 7.6113 0.0031258 -22.0215 1.216E-21 160 0 0 0.162659 -3.32 9.73266E-08 117.11 0.540055 2.51783 2.13386E-10 118.81 1 S PSAHNISSSGGAP 7.52626E-33 212.18 _DSTAPQRVPVASPSAHNIpSSSGGAPDR_ DSTAPQRVPVAS(0.001)PS(0.302)AHNIS(0.54)S(0.126)S(0.03)GGAPDR DS(-45.4)T(-51.53)APQRVPVAS(-29.02)PS(-2.52)AHNIS(2.52)S(-6.31)S(-12.48)GGAPDR 19 3 914.42614 0.099308 116160 0 0 0 0 0 0 116160 1669 1148;1149 376;376 376 2055;2056;4869;4870 2329;2330;5535;5536 46695 28590 Mix4_InSol_TiO2_1 5363 18853 11511 Mix4_TiO2_1_3 4359 Q7KZI7-13;Q7KZI7-14 Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-14|MARK2_HUMAN Isoform 14 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 1 74.7805 0.999994 53.065 1.99861E-16 168.39 0 0 0.999961 51.0996 3.95798E-16 160.94 1 74.7805 1.86764E-15 146.07 0.999998 60.8127 4.84304E-06 104.53 1 S PKQRRFSDQAGPA CAMK2;PKA 0.004788 1.99861E-16 168.39 _RFpSDQAGPAIPTSNSYSK_ RFS(1)DQAGPAIPTSNSYSK RFS(74.78)DQAGPAIPT(-74.78)S(-102.47)NS(-114.9)Y(-139.59)S(-141.61)K 3 2 1003.4544 0.80757 4217400 86740 0 0 2891600 0 857610 381430 1670 1148;1149 386;386 386 2055;2056;4869;4870 2329;2330;5535;5536 18855 11513 Mix4_TiO2_1_5 4410 18853 11511 Mix4_TiO2_1_3 4359 Q7KZI7-13;Q7KZI7-14 Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-14|MARK2_HUMAN Isoform 14 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 0.531704 1.33747 0.531704 1.33747 1.99861E-16 168.39 0 0 0.162709 -3.31612 3.95798E-16 160.94 0.306143 0 1.86764E-15 146.07 0.131562 -4.15141 4.84304E-06 104.53 1 S GPAIPTSNSYSKK GSK3 0.081 1.99861E-16 168.39 _FSDQAGPAIPTpSNSYSK_ FSDQAGPAIPT(0.014)S(0.532)NS(0.391)Y(0.032)S(0.032)K FS(-103.49)DQAGPAIPT(-15.64)S(1.34)NS(-1.34)Y(-12.27)S(-12.27)K 12 2 925.40384 0.33139 77471 77471 0 0 0 0 0 0 1671 1148;1149 388;388 388 2055;2056;4869;4870 2329;2330;5535;5536 46707 28605 Mix4_TiO2_Reinj_1_3 4877 18853 11511 Mix4_TiO2_1_3 4359 Q7KZI7-13;Q7KZI7-14 Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-14|MARK2_HUMAN Isoform 14 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 0.964016 15.626 0.843043 8.20547 1.99861E-16 168.39 0 0 0.964016 15.626 3.95798E-16 160.94 0.957786 16.1024 1.86764E-15 146.07 0.689842 8.16721 4.84304E-06 104.53 1 S AIPTSNSYSKKTQ 1.99861E-16 168.39 _RFSDQAGPAIPTSNpSYSK_ RFSDQAGPAIPT(0.004)S(0.026)NS(0.964)YS(0.006)K RFS(-123.25)DQAGPAIPT(-23.9)S(-15.63)NS(15.63)Y(-39.37)S(-22.4)K 15 2 1003.4544 -0.33627 6569400 1940100 0 0 3756400 0 571320 301580 1672 1148;1149 390;390 390 2055;2056;4869;4870 2329;2330;5535;5536 18851 11509 Mix4_InSol_Tio2_Reinj_1 5342 18853 11511 Mix4_TiO2_1_3 4359 Q7KZI7-13;Q7KZI7-14 Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-14|MARK2_HUMAN Isoform 14 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 0.800426 9.13814 0.179504 0 1.99861E-16 168.39 0 0 0.260966 -4.45901 3.95798E-16 160.94 0.420933 0 1.86764E-15 146.07 0.800426 9.13814 4.84304E-06 104.53 1 S PTSNSYSKKTQSN CK1 0.143 1.99861E-16 168.39 _FSDQAGPAIPTSNSYpSK_ FSDQAGPAIPT(0.03)S(0.017)NS(0.098)Y(0.056)S(0.8)K FS(-95.72)DQAGPAIPT(-14.33)S(-16.83)NS(-9.14)Y(-11.57)S(9.14)K 16 2 925.40384 0.5193 430500 0 0 0 0 0 0 430500 1673 1151 50 50 1035 1161 9760 5949 Mix4_TiO2_Reinj_1_2 1928 9760 5949 Mix4_TiO2_Reinj_1_2 1928 Q7L2Z9 Q7L2Z9 Q7L2Z9 >sp|Q7L2Z9|CENPQ_HUMAN Centromere protein Q OS=Homo sapiens GN=CENPQ PE=1 SV=1 0.991414 20.6248 0 0 0.991414 20.6248 0.00331229 72.889 1 S NHLKDLSSEGQTK 0.00331229 72.889 _DLpSSEGQTK_ DLS(0.991)S(0.009)EGQTK DLS(20.62)S(-20.62)EGQT(-72.89)K 3 2 522.71589 -0.19034 43075 0 0 0 43075 0 0 0 1674 1153 9 9 247;248 284;285 2483 1569 Mix4_TiO2_Reinj_1_4 8214 2479 1566 Mix4_TiO2_Reinj_1_5 8613 Q7L7X3 Q7L7X3 Q7L7X3 >sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Homo sapiens GN=TAOK1 PE=1 SV=1 1 45.8372 1 7.65998 0.0595198 55.572 1 45.8372 0.00155031 88.929 1 S STNRAGSLKDPEI CAMK2;CK2 0.042 0.00155031 88.929 _AGpSLKDPEIAELFFKEDPEK_ AGS(1)LKDPEIAELFFKEDPEK AGS(45.84)LKDPEIAELFFKEDPEK 3 3 781.71005 -0.74435 314310 234670 0 0 79637 0 0 0 1675 1153 421 421 482;6191 546;7069;7070 4500 2726 Mix4_TiO2_Reinj_1_5 2964 4491 2704 Mix4_InSol_TiO2_1 3211 Q7L7X3;Q7L7X3-2 Q7L7X3 Q7L7X3 >sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Homo sapiens GN=TAOK1 PE=1 SV=1;>sp|Q7L7X3-2|TAOK1_HUMAN Isoform 2 of Serine/threonine-protein kinase TAO1 OS=Homo sapiens GN=TAOK1 0.999995 55.1405 0.999966 47.2686 0.00106708 100.3 0.975596 16.7084 0.264835 26.411 0.999995 55.1405 0.000646768 108.25 0 0 0.999994 52.3731 8.12008E-05 125.87 0.999949 43.0482 0.00377528 89.366 1 S RASDPQSPPQVSR CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 8.12008E-05 125.87 _ASDPQpSPPQVSR_ ASDPQS(1)PPQVSR AS(-55.14)DPQS(55.14)PPQVS(-57.71)R 6 2 674.79828 -0.34051 11598000 242.87 1867000 53827 0 6706200 0 1226500 1744700 1676 1153 965 965 2465;4317 2798;2799;4910 41002 25218 Mix4_TiO2_Reinj_1_5 2539 41002 25218 Mix4_TiO2_Reinj_1_5 2539 Q7L7X3 Q7L7X3 Q7L7X3 >sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Homo sapiens GN=TAOK1 PE=1 SV=1 1 58.3285 1 46.2924 0.148635 46.292 0 0 1 58.3285 0.080046 58.329 0 0 0.854261 10.6905 0.859029 10.69 0.998731 31.9713 0.0320756 58.264 1 S SMGVRNSPQALRR PKA;Proline-directed 0.042 0.080046 58.329 _NpSPQALR_ NS(1)PQALR NS(58.33)PQALR 2 2 433.20002 -0.12316 2867200 340730 0 0 2001800 0 308940 215700 1677 1153 445 445 5907 6737 58266 35364 Mix4_InSol_TiO2_1 3443 58266 35364 Mix4_InSol_TiO2_1 3443 Q7L7X3;Q7L7X3-2 Q7L7X3 Q7L7X3 >sp|Q7L7X3|TAOK1_HUMAN Serine/threonine-protein kinase TAO1 OS=Homo sapiens GN=TAOK1 PE=1 SV=1;>sp|Q7L7X3-2|TAOK1_HUMAN Isoform 2 of Serine/threonine-protein kinase TAO1 OS=Homo sapiens GN=TAOK1 0.99983 38.2705 0.999674 34.8657 0.0695881 72.747 0 0 0.999396 32.4552 0.0691925 60.551 0.99983 38.2705 0.0696423 74.417 0.999431 32.4552 0.0691925 60.551 1 S ATIRTASLVTRQM CAMK2 0.042 0.0696423 74.417 _TApSLVTR_ TAS(1)LVTR T(-38.27)AS(38.27)LVT(-46.72)R 3 2 414.20477 -0.075013 1668400 148450 0 0 845440 0 354110 320390 1678 1155 378 378 6279 7174 62757 38175 Mix4_TiO2_1_5 5407 62759 38177 Mix4_TiO2_Reinj_1_5 6361 Q7Z2W4;Q7Z2W4-2;Q7Z2W4-3 Q7Z2W4 Q7Z2W4 >sp|Q7Z2W4|ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens GN=ZC3HAV1 PE=1 SV=3;>sp|Q7Z2W4-2|ZCCHV_HUMAN Isoform 2 of Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens GN=ZC3HAV1;>sp|Q7Z2W4-3|ZCCHV_HUMAN Isoform 3 of Zinc fing 0.91926 10.6173 0.91926 10.6173 0.149653 34.64 0 0 0.879126 8.61789 0.0575039 46.41 1 S RRKTVFSPTLPAA ERK/MAPK;Proline-directed 0.0034 0.0575039 46.41 _TVFpSPTLPAAR_ T(0.001)VFS(0.919)PT(0.08)LPAAR T(-29.66)VFS(10.62)PT(-10.62)LPAAR 4 2 620.3103 -0.27764 230050 57732 0 0 172320 0 0 0 1679 1158 735 735 4860 5526 46623 28555 Mix4_TiO2_Reinj_1_5 2496 46623 28555 Mix4_TiO2_Reinj_1_5 2496 Q7Z3C6;Q7Z3C6-2 Q7Z3C6 Q7Z3C6 >sp|Q7Z3C6|ATG9A_HUMAN Autophagy-related protein 9A OS=Homo sapiens GN=ATG9A PE=1 SV=3;>sp|Q7Z3C6-2|ATG9A_HUMAN Isoform 2 of Autophagy-related protein 9A OS=Homo sapiens GN=ATG9A 0.999843 38.0347 0.999592 33.8924 4.02271E-06 100.23 0.999843 38.0347 2.57961E-21 166.26 1 S VWHRRESDESGES CAMK2;PKA 0.004788 2.57961E-21 166.26 _REpSDESGESAPDEGGEGAR_ RES(1)DESGESAPDEGGEGAR RES(38.03)DES(-38.03)GES(-78.52)APDEGGEGAR 3 2 1007.8847 0.064101 131700 40758 0 0 90944 0 0 0 1680 1159 695 695 5679 6467 55650 34099 Mix4_TiO2_Reinj_1_5 4276 55650 34099 Mix4_TiO2_Reinj_1_5 4276 Q7Z3G6 Q7Z3G6 Q7Z3G6 >sp|Q7Z3G6|PRIC2_HUMAN Prickle-like protein 2 OS=Homo sapiens GN=PRICKLE2 PE=1 SV=2 0.9346 11.5505 0 0 0 0 0.9346 11.5505 0.00467619 79.775 1 S RSRRSRSDNALHL CAMK2 0.042 0.00467619 79.775 _SRpSDNALHLASER_ S(0.065)RS(0.935)DNALHLASER S(-11.55)RS(11.55)DNALHLAS(-79.78)ER 3 3 512.57025 -0.26325 204950 0 0 0 204950 0 0 0 1681 1159 753 753 6291 7188 62937 38331 Mix4_TiO2_Reinj_1_5 7149 62937 38331 Mix4_TiO2_Reinj_1_5 7149 Q7Z3G6 Q7Z3G6 Q7Z3G6 >sp|Q7Z3G6|PRIC2_HUMAN Prickle-like protein 2 OS=Homo sapiens GN=PRICKLE2 PE=1 SV=2 0.999819 37.4156 0.999819 37.4156 1.80464E-12 102.73 1 S QCPRTVSDLALQN CAMK2 0.042 1.80464E-12 102.73 _TVpSDLALQNAFGDR_ TVS(1)DLALQNAFGDR T(-37.42)VS(37.42)DLALQNAFGDR 3 2 793.86415 -0.059995 0 0 0 0 0 0 0 0 1682 1161 1183 1183 1191 1338;1341 11171 6840 Mix4_TiO2_1_5 7450 11180 6848 Mix4_TiO2_Reinj_1_1 8366 Q7Z3U7;Q7Z3U7-4;Q7Z3U7-2;Q7Z3U7-3 Q7Z3U7 Q7Z3U7 >sp|Q7Z3U7|MON2_HUMAN Protein MON2 homolog OS=Homo sapiens GN=MON2 PE=1 SV=2;>sp|Q7Z3U7-4|MON2_HUMAN Isoform 4 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-2|MON2_HUMAN Isoform 2 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-3|MO 0.832369 6.95961 0.832369 6.95961 0.00340025 77.353 0 0 0.756274 4.91778 7.7747E-12 119.35 1 S VSPVRDSDKPETP PKA 0.042 7.7747E-12 119.35 _DpSDKPETPPVVNVPVPVLIGPISGM(ox)SR_ DS(0.832)DKPET(0.168)PPVVNVPVPVLIGPISGMSR DS(6.96)DKPET(-6.96)PPVVNVPVPVLIGPIS(-77.35)GMS(-77.35)R 2 3 966.15571 0.47705 858300 2.3758 197070 0 0 661230 0 0 0 1683 1161 205 205 5855 6677 57760 35123 Mix4_TiO2_Reinj_1_5 3183 57759 35122 Mix4_InSol_Tio2_Reinj_1 3442 Q7Z3U7;Q7Z3U7-4;Q7Z3U7-2 Q7Z3U7 Q7Z3U7 >sp|Q7Z3U7|MON2_HUMAN Protein MON2 homolog OS=Homo sapiens GN=MON2 PE=1 SV=2;>sp|Q7Z3U7-4|MON2_HUMAN Isoform 4 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-2|MON2_HUMAN Isoform 2 of Protein MON2 homolog OS=Homo sapiens GN=MON2 0.9952 26.1765 0 0 0.9952 26.1765 0.243559 26.177 0.969282 18.0008 0.382888 18.001 0.931624 11.3659 0.0533567 44.89 1 S GNSNRRSVSTLKP AURORA;AURORA-1;AURORA-A;CK1;PKA 0.006142092 0.0533567 44.89 _pSVSTLKPCAK_ S(0.995)VS(0.002)T(0.002)LKPCAK S(26.18)VS(-26.18)T(-26.18)LKPCAK 1 2 585.78306 0.32468 778450 0 0 0 390440 0 209650 178360 1684 1161 1215 1215 5943;5944 6776;6777 58545 35502 Mix4_InSol_Tio2_Reinj_1 2090 58545 35502 Mix4_InSol_Tio2_Reinj_1 2090 Q7Z3U7;Q7Z3U7-4;Q7Z3U7-2;Q7Z3U7-3 Q7Z3U7 Q7Z3U7 >sp|Q7Z3U7|MON2_HUMAN Protein MON2 homolog OS=Homo sapiens GN=MON2 PE=1 SV=2;>sp|Q7Z3U7-4|MON2_HUMAN Isoform 4 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-2|MON2_HUMAN Isoform 2 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-3|MO 0.999994 52.1259 0.99998 46.971 0.0694858 69.593 0 0 0.999992 50.7296 0.0696974 76.116 0 0 0.999992 50.7296 0.0696974 76.116 0.999994 52.1259 0.015923 103.54 1 S PFVRTDSIGEKLG CAMK2;CK2 0.042 0.015923 103.54 _TDpSIGEK_ TDS(1)IGEK T(-52.13)DS(52.13)IGEK 3 2 415.17059 -0.13794 2599000 88648 0 0 343470 0 1308200 858660 1685 1163 629 629 1348 1518 12699 7852 Mix4_TiO2_Reinj_1_3 7627 12700 7853 Mix4_TiO2_Reinj_1_3 7647 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 0.994112 25.2926 0.958814 16.6801 5.96871E-24 162.43 0.994112 25.2926 7.31054E-25 174.3 0.0146192 -17.4336 5.65727E-07 106.96 0.775765 6.47859 0.000277407 89.954 1 S SQNPLASPTNTLL Proline-directed 0.05 7.31054E-25 174.3 _DYEIESQNPLApSPTNTLLGSAK_ DYEIESQNPLAS(0.994)PT(0.003)NT(0.003)LLGSAK DY(-167.33)EIES(-105.08)QNPLAS(25.29)PT(-25.29)NT(-25.29)LLGS(-49.83)AK 12 3 810.0475 0.092656 5403600 1769700 0 0 3388600 0 0 245260 1686 1163 212 212 2087 2364 19122 11630 Mix4_InSol_TiO2_1 3158 19123 11631 Mix4_InSol_Tio2_Reinj_1 3157 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 0.999749 36.0012 0.946678 12.4958 3.49355E-09 127.87 0.95953 13.8014 0.0079057 74.477 0.999749 36.0012 1.09732E-09 134.38 0.999538 33.3536 2.40352E-13 153.93 1 S GADNDGSGSESGY CK2;GSK3 0.081 2.40352E-13 153.93 _GADNDGpSGSESGYTTPK_ GADNDGS(1)GSESGYTTPK GADNDGS(36)GS(-36)ES(-77.54)GY(-122.5)T(-118.36)T(-124.5)PK 7 2 861.82816 0.98615 704750 115330 0 0 337620 0 147290 104510 1687 1163 652 652 3981 4535 37693 23143 Mix4_TiO2_1_3 6530 37696 23147 Mix4_TiO2_Reinj_1_3 7342 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 0.999959 43.8892 0.999959 43.8892 0.000820919 80.712 0.999909 40.4091 0.00166769 96.75 0.957025 13.4771 0.212875 28.719 0.989222 19.6274 0.345224 19.627 1 S GLERNDSWGSFDL CAMK2;CHK1;CHK1/2;PKD 0.003192 0.00166769 96.75 _NDpSWGSFDLR_ NDS(1)WGSFDLR NDS(43.89)WGS(-43.89)FDLR 3 2 638.75334 -0.052643 1070200 319990 0 0 643920 0 54371 51914 1688 1163 230 230 4966 5647 47920 29299 Mix4_InSol_Tio2_Reinj_1 4690 47919 29298 Mix4_InSol_TiO2_1 4712 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 1 18.043 1 72.1355 0.0112308 72.136 1 18.043 0.826955 18.043 1 S RKARRNSAKGCEN CAMK2;PKA 0.004788 0.0112308 72.136 _RNpSAKGCENLNIVQDK_ RNS(1)AKGCENLNIVQDK RNS(18.04)AKGCENLNIVQDK 3 3 642.63482 0.32449 320590 0 0 0 0 0 156420 164170 1689 1163 572 572 5059;6226 5753;7112 48905 29890 Mix4_TiO2_Reinj_1_4 6590 48902 29887 Mix4_TiO2_1_3 5812 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 0.995719 24.8622 0.964269 14.3116 0.00394147 88.77 0.995719 24.8622 0.0369852 54.632 0.970822 15.5203 0.257752 26.984 0 0 1 S ELEKRTSPQVLGS CHK1;PKA;PKD;Proline-directed 0.020748 0.00394147 88.77 _RTpSPQVLGSILK_ RT(0.003)S(0.996)PQVLGS(0.001)ILK RT(-24.86)S(24.86)PQVLGS(-29.85)ILK 3 2 689.87633 -0.078979 1852200 432870 0 0 1272200 0 147070 0 1690 1164 222 222 2369 2681 21913 13626 Mix4_TiO2_1_5 5789 21912 13624 Mix4_TiO2_1_3 5869 Q7Z434 Q7Z434 Q7Z434 >sp|Q7Z434|MAVS_HUMAN Mitochondrial antiviral-signaling protein OS=Homo sapiens GN=MAVS PE=1 SV=2 0.996812 24.9517 0.996812 24.9517 1.75929E-06 118.98 0 0 0.977933 16.4775 3.76807E-05 114.98 1 S PSRGPVSPSVSFQ ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 1.75929E-06 118.98 _GPVpSPSVSFQPLAR_ GPVS(0.997)PS(0.003)VSFQPLAR GPVS(24.95)PS(-24.95)VS(-66.04)FQPLAR 4 2 761.3767 -0.24208 1496500 386730 0 0 1109800 0 0 0 1691 1164 224 224 2369 2681 21915 13629 Mix4_TiO2_Reinj_1_4 6638 21912 13624 Mix4_TiO2_1_3 5869 Q7Z434 Q7Z434 Q7Z434 >sp|Q7Z434|MAVS_HUMAN Mitochondrial antiviral-signaling protein OS=Homo sapiens GN=MAVS PE=1 SV=2 0.513019 1.14963 0.00319181 -24.9457 1.75929E-06 118.98 0 0 0.513019 1.14963 3.76807E-05 114.98 1 S RGPVSPSVSFQPL 1.75929E-06 118.98 _GPVSPpSVSFQPLAR_ GPVS(0.394)PS(0.513)VS(0.093)FQPLAR GPVS(-1.15)PS(1.15)VS(-7.4)FQPLAR 6 2 761.3767 -0.27013 120280 0 0 0 120280 0 0 0 1692 1164 253 253 3625 4085 34085 21032 Mix4_TiO2_Reinj_1_3 6431 34085 21032 Mix4_TiO2_Reinj_1_3 6431 Q7Z434 Q7Z434 Q7Z434 >sp|Q7Z434|MAVS_HUMAN Mitochondrial antiviral-signaling protein OS=Homo sapiens GN=MAVS PE=1 SV=2 0.267033 0 0 0 0.267033 0 1.04526E-12 125.15 1 S VVSTGTSFSSSSP CK1;GSK3 0.081 1.04526E-12 125.15 _LPGPTGSVVSTGpTSFSSSSPGLASAGAAEGK_ LPGPT(0.001)GS(0.001)VVS(0.214)T(0.214)GT(0.267)S(0.267)FS(0.037)SSSPGLASAGAAEGK LPGPT(-25.67)GS(-24.75)VVS(-0.97)T(-0.97)GT(0)S(0)FS(-8.6)S(-31.64)S(-46.49)S(-67.13)PGLAS(-107.74)AGAAEGK 14 3 948.78148 0.53503 0 0 0 0 0 0 0 0 1693 1165 600 600 5678 6466 55644 34096 Mix4_InSol_Tio2_Reinj_1 3852 55646 34098 Mix4_TiO2_Reinj_1_5 3574 Q7Z460;Q7Z460-3;Q7Z460-2 Q7Z460 Q7Z460 >sp|Q7Z460|CLAP1_HUMAN CLIP-associating protein 1 OS=Homo sapiens GN=CLASP1 PE=1 SV=1;>sp|Q7Z460-3|CLAP1_HUMAN Isoform 3 of CLIP-associating protein 1 OS=Homo sapiens GN=CLASP1;>sp|Q7Z460-2|CLAP1_HUMAN Isoform 2 of CLIP-associating protein 1 OS=Homo sapien 0.852052 8.44374 0.818936 6.55419 0.010697 72.624 0.821177 6.62012 0.00323813 80.604 0 0 0.852052 8.44374 0.709045 15.151 1 S SLQRSRSDIDVNA CAMK2;CHK1;CHK1/2;CK2;PKD 0.003192 0.00323813 80.604 _SRpSDIDVNAAASAK_ S(0.122)RS(0.852)DIDVNAAAS(0.026)AK S(-8.44)RS(8.44)DIDVNAAAS(-15.15)AK 3 2 742.84068 0.92546 169120 22674 0 0 106370 0 0 40069 1694 1167 1374 1374 2095 2372 19177 11651 Mix4_TiO2_Reinj_1_1 5889 19177 11651 Mix4_TiO2_Reinj_1_1 5889 Q7Z5J4;Q7Z5J4-2;Q7Z5J4-3 Q7Z5J4 Q7Z5J4 >sp|Q7Z5J4|RAI1_HUMAN Retinoic acid-induced protein 1 OS=Homo sapiens GN=RAI1 PE=1 SV=2;>sp|Q7Z5J4-2|RAI1_HUMAN Isoform 2 of Retinoic acid-induced protein 1 OS=Homo sapiens GN=RAI1;>sp|Q7Z5J4-3|RAI1_HUMAN Isoform 3 of Retinoic acid-induced protein 1 OS=Hom 1 97.8709 0 0 1 97.8709 2.85188E-05 97.871 1 S LKGAGGSPVGVEE Proline-directed 0.05 2.85188E-05 97.871 _GAGGpSPVGVEEGLVNVGTGQK_ GAGGS(1)PVGVEEGLVNVGTGQK GAGGS(97.87)PVGVEEGLVNVGT(-97.87)GQK 5 2 996.47533 0.77981 69172 0 0 0 69172 0 0 0 1695 1168 306 306 4981;4982 5663;5664 48047 29381 Mix4_TiO2_Reinj_1_5 4544 48047 29381 Mix4_TiO2_Reinj_1_5 4544 Q7Z5K2-3;Q7Z5K2-2;Q7Z5K2 Q7Z5K2-3 Q7Z5K2-3 >sp|Q7Z5K2-3|WAPL_HUMAN Isoform 3 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2-2|WAPL_HUMAN Isoform 2 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2|WAPL_HUMAN Wings apart-like protein homolog OS=Homo sap 0.99336 21.5355 0.958241 13.4543 0.489334 14.456 0.99336 21.5355 0.0591151 55.045 0.140833 -9.45377 0.903517 15.882 0.522681 1.0894 1.38971 1.0894 2 S FGKRPESPSEISP CAMK2;CK2;ERK/MAPK;PKA;Proline-directed;WW GroupIV 0.000145 0.0591151 55.045 _RPEpSPSEIpSPIKGSVR_ RPES(0.993)PS(0.223)EIS(0.709)PIKGS(0.074)VR RPES(21.54)PS(-5.12)EIS(5.12)PIKGS(-9.86)VR 4 2 949.94228 0.20569 189170 31873 0 0 121880 0 0 35419 1696 1168 308 308 4981;4982 5663;5664 48045 29379 Mix4_InSol_TiO2_1 4843 48047 29381 Mix4_TiO2_Reinj_1_5 4544 Q7Z5K2-3;Q7Z5K2-2;Q7Z5K2 Q7Z5K2-3 Q7Z5K2-3 >sp|Q7Z5K2-3|WAPL_HUMAN Isoform 3 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2-2|WAPL_HUMAN Isoform 2 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2|WAPL_HUMAN Wings apart-like protein homolog OS=Homo sap 0.865179 9.45377 0.074916 -13.4543 0.489334 14.456 0.223039 -5.12314 0.0591151 55.045 0.865179 9.45377 0.903517 15.882 0.477319 -1.0894 1.38971 1.0894 2 S KRPESPSEISPIK 0.0591151 55.045 _RPESPpSEIpSPIKGSVR_ RPES(0.141)PS(0.865)EIS(0.931)PIKGS(0.063)VR RPES(-9.45)PS(9.45)EIS(14.79)PIKGS(-15.88)VR 6 3 633.63061 1.8746 104400 0 0 0 0 0 104400 0 1697 1168 311 311 4981;4982 5663;5664 48041 29378 Mix4_TiO2_1_5 3533 48047 29381 Mix4_TiO2_Reinj_1_5 4544 Q7Z5K2-3;Q7Z5K2-2;Q7Z5K2 Q7Z5K2-3 Q7Z5K2-3 >sp|Q7Z5K2-3|WAPL_HUMAN Isoform 3 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2-2|WAPL_HUMAN Isoform 2 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2|WAPL_HUMAN Wings apart-like protein homolog OS=Homo sap 0.966843 14.456 0.966843 14.456 0.489334 14.456 0.709142 5.12314 0.0591151 55.045 0.930731 14.7929 0.903517 15.882 0.522681 1.0894 1.38971 1.0894 2 S ESPSEISPIKGSV CDK1;CDK2;CK1;Proline-directed 0.0057 0.0591151 55.045 _RPEpSPSEIpSPIK_ RPES(0.958)PS(0.075)EIS(0.967)PIK RPES(13.45)PS(-13.45)EIS(14.46)PIK 9 2 750.33077 -0.12781 293570 31873 0 0 121880 0 104400 35419 1698 1168 162 162 6381 7301 64466 39563 Mix4_TiO2_1_5 6379 64466 39563 Mix4_TiO2_1_5 6379 Q7Z5K2-3;Q7Z5K2-2;Q7Z5K2 Q7Z5K2-3 Q7Z5K2-3 >sp|Q7Z5K2-3|WAPL_HUMAN Isoform 3 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2-2|WAPL_HUMAN Isoform 2 of Wings apart-like protein homolog OS=Homo sapiens GN=WAPAL;>sp|Q7Z5K2|WAPL_HUMAN Wings apart-like protein homolog OS=Homo sap 0.993702 22.0109 0.993702 22.0109 5.49247E-12 133.24 0 0 1 S DPFGFDSDDESLP CK2;GSK3 0.081 5.49247E-12 133.24 _VEEESTGDPFGFDpSDDESLPVSSK_ VEEESTGDPFGFDS(0.994)DDES(0.006)LPVSSK VEEES(-92.41)T(-98.91)GDPFGFDS(22.01)DDES(-22.01)LPVS(-46.58)S(-46.58)K 14 2 1327.0393 -0.028533 136690 136690 0 0 0 0 0 0 1699 1169 1395 1395 187 216 1945 1298 Mix4_TiO2_1_1 2271 1945 1298 Mix4_TiO2_1_1 2271 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 1 53.4224 1 53.4224 0.0275865 53.422 0 0 1 S MDQRAESPEEVAC CAMK2;CK2;Proline-directed 0.042 0.0275865 53.422 _AEpSPEEVACR_ AES(1)PEEVACR AES(53.42)PEEVACR 3 2 614.23921 -0.22336 19722 19722 0 0 0 0 0 0 1700 1169 2887 2887 252 289 2495 1578 Mix4_TiO2_1_1 3722 2495 1578 Mix4_TiO2_1_1 3722 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.758336 7.9768 0.758336 7.9768 9.12677E-07 114.05 0.465869 0 0.00492684 75.762 0 0 0.243156 -3.24814 0.749374 24.726 1 S EQPRAGSSTPGDA CAMK2 0.042 9.12677E-07 114.05 _AGpSSTPGDAPPAVAEVQGR_ AGS(0.758)S(0.121)T(0.121)PGDAPPAVAEVQGR AGS(7.98)S(-7.98)T(-7.98)PGDAPPAVAEVQGR 3 2 923.92019 0.27736 36674 36674 0 0 0 0 0 0 1701 1169 2888 2888 252 289 2496 1579 Mix4_TiO2_Reinj_1_1 4198 2495 1578 Mix4_TiO2_1_1 3722 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.465869 0 0.120832 -7.9768 9.12677E-07 114.05 0.465869 0 0.00492684 75.762 0 0 0.243156 -3.24814 0.749374 24.726 1 S QPRAGSSTPGDAP 9.12677E-07 114.05 _AGpSSTPGDAPPAVAEVQGR_ AGS(0.466)S(0.466)T(0.068)PGDAPPAVAEVQGR AGS(0)S(0)T(-8.34)PGDAPPAVAEVQGR 4 2 923.92019 0.063198 0 0 0 0 0 0 0 0 1702 1169 1903 1903 2442 2769 22956 14356 Mix4_TiO2_Reinj_2_1 3815 22953 14353 Mix4_InSol_Tio2_Reinj_1 5772 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.533061 1.4268 6.26788E-06 -52.0288 0.00118959 92.974 0 0 5.51409E-05 -42.585 0.00146745 91.296 0.533061 1.4268 0.013525 69.946 0.0209802 -16.5957 0.00021119 99.958 1.82343E-05 -47.391 0.000192724 101.56 1 S LPAPRGSGTASDD GSK3;PKA 0.042 0.000192724 101.56 _GpSGTASDDEFENLR_ GS(0.533)GT(0.083)AS(0.384)DDEFENLR GS(1.43)GT(-8.07)AS(-1.43)DDEFENLR 2 2 789.30941 0.1389 18533 0 0 0 0 18533 0 0 1703 1169 1907 1907 2442 2769 22954 14354 Mix4_TiO2_1_1 4308 22953 14353 Mix4_InSol_Tio2_Reinj_1 5772 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.999993 52.0288 0.999993 52.0288 0.00118959 92.974 0 0 0.999938 42.585 0.00146745 91.296 0.383793 -1.4268 0.013525 69.946 0.999729 36.0966 0.00021119 99.958 0.999971 47.391 0.000192724 101.56 1 S RGSGTASDDEFEN CK1;CK2 0.117 0.000192724 101.56 _GSGTApSDDEFENLR_ GSGTAS(1)DDEFENLR GS(-52.03)GT(-60.79)AS(52.03)DDEFENLR 6 2 789.30941 0.35991 1685700 171920 0 0 660590 0 400270 452920 1704 1169 3555 3555 2448 2776 23015 14386 Mix4_InSol_TiO2_1 3467 23015 14386 Mix4_InSol_TiO2_1 3467 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.972582 15.512 0.972582 15.512 0.0151027 65.598 0.820089 6.591 0.110469 49.169 1 S TTKGSKSPAKVSD CDK1;CDK2;Proline-directed 0.0057 0.0151027 65.598 _GSKpSPAKVSDGGSSSTDFK_ GS(0.027)KS(0.973)PAKVSDGGSSSTDFK GS(-15.51)KS(15.51)PAKVS(-40.79)DGGS(-65.6)S(-65.6)S(-65.6)T(-65.6)DFK 4 3 641.28948 -0.88378 402380 0 0 0 0 0 199170 203200 1705 1169 3818 3818 4856 5520 46573 28527 Mix4_TiO2_1_1 3410 46573 28527 Mix4_TiO2_1_1 3410 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.536216 0.63576 0.536216 0.63576 0.00013462 91.395 0 0 1 S VDQPSPSAQDTQS CK2 0.117 0.00013462 91.395 _REESPM(ox)DVDQPSPpSAQDTQSIASDGTPQGEK_ REESPMDVDQPS(0.463)PS(0.536)AQDTQSIASDGTPQGEK REES(-31.92)PMDVDQPS(-0.64)PS(0.64)AQDT(-33.63)QS(-46.55)IAS(-58.58)DGT(-74.66)PQGEK 14 3 1128.4787 -0.021102 75796 0.13373 75796 0 0 0 0 0 0 1706 1170 169 169 2799 3189 26826 16777 Mix4_TiO2_Reinj_1_2 5867 26826 16777 Mix4_TiO2_Reinj_1_2 5867 Q86T03-2;Q86T03 Q86T03-2 Q86T03-2 >sp|Q86T03-2|TM55B_HUMAN Isoform 2 of Transmembrane protein 55B OS=Homo sapiens GN=TMEM55B;>sp|Q86T03|TM55B_HUMAN Transmembrane protein 55B OS=Homo sapiens GN=TMEM55B PE=1 SV=1 1 51.7084 1 51.7084 0.114278 51.708 1 S VHPGPLSPEPQPM ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.114278 51.708 _IINLGPVHPGPLpSPEPQPM(ox)GVR_ IINLGPVHPGPLS(1)PEPQPMGVR IINLGPVHPGPLS(51.71)PEPQPMGVR 13 3 801.07478 0.14859 40182 0 0 0 40182 0 0 0 1707 1173 37 37 3424 3868 32168 19880 Mix4_TiO2_Reinj_1_6 4188 32168 19880 Mix4_TiO2_Reinj_1_6 4188 Q86U90 Q86U90 Q86U90 >sp|Q86U90|YRDC_HUMAN YrdC domain-containing protein, mitochondrial OS=Homo sapiens GN=YRDC PE=1 SV=1 1 53.2299 1 33.1764 0.324039 33.176 0 0 1 53.2299 0.0639863 53.23 1 S RLFRPPSPAPAAP CAMK2;CHK1;CHK1/2;ERK/MAPK;PKD;Proline-directed;WW GroupIV 0.0023175 0.0639863 53.23 _LFRPPpSPAPAAPGAR_ LFRPPS(1)PAPAAPGAR LFRPPS(53.23)PAPAAPGAR 6 3 528.93973 -0.032239 236410 47789 0 0 188620 0 0 0 1708 1174 99 99 2904 3308 27804 17320 Mix4_TiO2_Reinj_1_3 7251 27804 17320 Mix4_TiO2_Reinj_1_3 7251 Q86UE8;Q86UE8-2 Q86UE8 Q86UE8 >sp|Q86UE8|TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens GN=TLK2 PE=1 SV=2;>sp|Q86UE8-2|TLK2_HUMAN Isoform 2 of Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens GN=TLK2 0.816646 6.48829 0.816646 6.48829 0.0469843 56.976 1 S GSAPGTSPGRSVP CDK1;CDK2;GSK3;Proline-directed 0.0057 0.0469843 56.976 _ISDYFEFAGGSAPGTpSPGR_ ISDYFEFAGGSAPGT(0.183)S(0.817)PGR IS(-56.98)DY(-56.98)FEFAGGS(-43.89)APGT(-6.49)S(6.49)PGR 16 2 998.42784 0.15604 394220 0 0 0 394220 0 0 0 1709 1177 10 10 2463;4897 2795;5568;5569 47036 28766 Mix4_TiO2_Reinj_1_4 2151 47036 28766 Mix4_TiO2_Reinj_1_4 2151 Q86UX6 Q86UX6 Q86UX6 >sp|Q86UX6|ST32C_HUMAN Serine/threonine-protein kinase 32C OS=Homo sapiens GN=STK32C PE=1 SV=1 0.967148 14.5561 0.947398 12.573 0.14732 41.492 0 0 0.967148 14.5561 0.0144187 69.447 0.840448 7.24317 0.498638 28.738 0.00299959 -25.1901 0.00507004 77.65 2 S GAERRGSSAAASP CAMK2;PKA 0.004788 0.0144187 69.447 _RGpSSAAASPGpSPPPGR_ RGS(0.967)S(0.033)AAAS(0.147)PGS(0.853)PPPGR RGS(14.56)S(-14.56)AAAS(-7.62)PGS(7.62)PPPGR 3 2 806.33745 0.26176 131840 23741 0 0 83644 0 24452 0 1710 1177 18 18 2463;4897 2795;5568;5569 23147 14444 Mix4_InSol_Tio2_Reinj_1 2400 23150 14453 Mix4_TiO2_Reinj_1_4 2229 Q86UX6 Q86UX6 Q86UX6 >sp|Q86UX6|ST32C_HUMAN Serine/threonine-protein kinase 32C OS=Homo sapiens GN=STK32C PE=1 SV=1 0.999962 44.2566 0.999614 34.132 0.000848616 93.686 0 0 0.999905 40.2176 1.00683E-09 152.39 0.996696 24.7948 0.00169312 87.96 0.999962 44.2566 0.00507004 77.65 1 S AAASPGSPPPGRA CK1;ERK/MAPK;Proline-directed 0.0025 1.00683E-09 152.39 _GSSAAASPGpSPPPGR_ GSSAAASPGS(1)PPPGR GS(-70.4)S(-70.4)AAAS(-44.26)PGS(44.26)PPPGR 10 2 688.30373 0.078491 1736600 209150 0 0 1021700 0 266830 238980 1711 1178 659 659 1620 1819 14918 9032 Mix4_TiO2_Reinj_1_5 7461 14918 9032 Mix4_TiO2_Reinj_1_5 7461 Q86V48;Q86V48-3;Q86V48-2 Q86V48 Q86V48 >sp|Q86V48|LUZP1_HUMAN Leucine zipper protein 1 OS=Homo sapiens GN=LUZP1 PE=1 SV=2;>sp|Q86V48-3|LUZP1_HUMAN Isoform 3 of Leucine zipper protein 1 OS=Homo sapiens GN=LUZP1;>sp|Q86V48-2|LUZP1_HUMAN Isoform 2 of Leucine zipper protein 1 OS=Homo sapiens GN=LUZ 1 82.0743 0.99448 25.5669 0.681954 25.567 1 82.0743 0.00115569 84.817 1 S GREKPDSDDDLDI CK2 0.117 0.00115569 84.817 _EKPDpSDDDLDIASLVTAK_ EKPDS(1)DDDLDIASLVTAK EKPDS(82.07)DDDLDIAS(-82.07)LVT(-84.82)AK 5 3 671.30843 0.083003 269010 36913 0 0 232100 0 0 0 1712 1179 1424 1424 2645;5477 3008;6233 53414 32632 Mix4_TiO2_Reinj_1_5 6983 53412 32630 Mix4_TiO2_1_5 6096 Q86VI3 Q86VI3 Q86VI3 >sp|Q86VI3|IQGA3_HUMAN Ras GTPase-activating-like protein IQGAP3 OS=Homo sapiens GN=IQGAP3 PE=1 SV=2 0.990961 20.3994 0.982964 17.6116 2.64141E-05 128.54 0 0 0.990961 20.3994 0.00464271 79.932 0 0 0 0 0 0 1 S PLRRHRSLTAHSL CAMK2;CHK1;CHK1/2;PKD 0.003192 2.64141E-05 128.54 _pSLTAHSLLPLAEK_ S(0.991)LT(0.009)AHSLLPLAEK S(20.4)LT(-20.4)AHS(-79.78)LLPLAEK 1 2 730.38145 0.16543 3824500 153280 0 0 3671200 0 0 0 1713 1179 539 539 6459 7388 65253 40018 Mix4_TiO2_Reinj_1_5 8169 65253 40018 Mix4_TiO2_Reinj_1_5 8169 Q86VI3 Q86VI3 Q86VI3 >sp|Q86VI3|IQGA3_HUMAN Ras GTPase-activating-like protein IQGAP3 OS=Homo sapiens GN=IQGAP3 PE=1 SV=2 1 94.372 0 0 0 0 1 94.372 0.000372061 94.372 1 S EALDKGSPEKTLS CDK1;CDK2;Proline-directed 0.0057 0.000372061 94.372 _VLAVSLINEALDKGpSPEK_ VLAVSLINEALDKGS(1)PEK VLAVS(-94.37)LINEALDKGS(94.37)PEK 15 3 655.00977 -0.2347 335600 0 0 0 335600 0 0 0 1714 1180 534 534 3467 3913 32660 20245 Mix4_TiO2_Reinj_1_5 4091 32660 20245 Mix4_TiO2_Reinj_1_5 4091 Q86VM9;Q86VM9-2 Q86VM9 Q86VM9 >sp|Q86VM9|ZCH18_HUMAN Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens GN=ZC3H18 PE=1 SV=2;>sp|Q86VM9-2|ZCH18_HUMAN Isoform 2 of Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens GN=ZC3H18 0.992353 21.132 0 0 0 0 0.992353 21.132 0.00107639 84.331 0 0 0 0 1 S KLGVSVSPSRARR CDK1;CDK2;Proline-directed 0.0057 0.00107639 84.331 _LGVSVpSPSR_ LGVSVS(0.992)PS(0.008)R LGVS(-74.56)VS(21.13)PS(-21.13)R 6 2 491.24188 -0.027183 128890 0 0 0 128890 0 0 0 1715 1182 308 308 2493 2833 23460 14597 Mix4_TiO2_Reinj_1_5 3000 23460 14597 Mix4_TiO2_Reinj_1_5 3000 Q86VV8;Q86VV8-3;Q86VV8-5;Q86VV8-4;Q86VV8-2 Q86VV8 Q86VV8 >sp|Q86VV8|RTTN_HUMAN Rotatin OS=Homo sapiens GN=RTTN PE=1 SV=3;>sp|Q86VV8-3|RTTN_HUMAN Isoform 3 of Rotatin OS=Homo sapiens GN=RTTN;>sp|Q86VV8-5|RTTN_HUMAN Isoform 5 of Rotatin OS=Homo sapiens GN=RTTN;>sp|Q86VV8-4|RTTN_HUMAN Isoform 4 of Rotatin OS=Homo s 0.700022 6.69203 0.304206 0 1.8269 5.8931 0.512382 1.36961 0.895371 29.056 0.700022 6.69203 8.61504E-07 101.14 0.0544116 -11.1296 0.0104628 68.406 0.557903 2.05972 0.00954401 69.444 1 S QNPSPGSSSPRPS CK1 0.081 8.61504E-07 101.14 _GTHHSQNPSPGpSSSPRPSVVGR_ GTHHSQNPSPGS(0.7)S(0.15)S(0.15)PRPSVVGR GT(-94.33)HHS(-75.38)QNPS(-38.37)PGS(6.69)S(-6.69)S(-6.69)PRPS(-54.92)VVGR 12 3 770.02413 -0.076404 605930 0 38921 0 420830 0 0 146180 1716 1182 309 309 2493 2833 23459 14595 Mix4_TiO2_Reinj_1_1 2595 23460 14597 Mix4_TiO2_Reinj_1_5 3000 Q86VV8;Q86VV8-3;Q86VV8-5;Q86VV8-4;Q86VV8-2 Q86VV8 Q86VV8 >sp|Q86VV8|RTTN_HUMAN Rotatin OS=Homo sapiens GN=RTTN PE=1 SV=3;>sp|Q86VV8-3|RTTN_HUMAN Isoform 3 of Rotatin OS=Homo sapiens GN=RTTN;>sp|Q86VV8-5|RTTN_HUMAN Isoform 5 of Rotatin OS=Homo sapiens GN=RTTN;>sp|Q86VV8-4|RTTN_HUMAN Isoform 4 of Rotatin OS=Homo s 0.48807 0 0.304206 0 1.8269 5.8931 0.0965458 -7.2486 0.895371 29.056 0.48807 0 8.61504E-07 101.14 0.216522 -5.13151 0.0104628 68.406 0.0932128 -7.77083 0.00954401 69.444 1 S NPSPGSSSPRPSV CK1 0.143 8.61504E-07 101.14 _GTHHSQNPSPGSpSSPRPSVVGR_ GTHHS(0.001)QNPS(0.009)PGS(0.015)S(0.488)S(0.488)PRPSVVGR GT(-55.76)HHS(-29.11)QNPS(-17.56)PGS(-15.22)S(0)S(0)PRPS(-45.51)VVGR 13 3 770.02413 -0.23482 0 0 0 0 0 0 0 0 1717 1182 310 310 2493 2833 23455 14591 Mix4_InSol_TiO2_1 3426 23460 14597 Mix4_TiO2_Reinj_1_5 3000 Q86VV8;Q86VV8-3;Q86VV8-5;Q86VV8-4;Q86VV8-2 Q86VV8 Q86VV8 >sp|Q86VV8|RTTN_HUMAN Rotatin OS=Homo sapiens GN=RTTN PE=1 SV=3;>sp|Q86VV8-3|RTTN_HUMAN Isoform 3 of Rotatin OS=Homo sapiens GN=RTTN;>sp|Q86VV8-5|RTTN_HUMAN Isoform 5 of Rotatin OS=Homo sapiens GN=RTTN;>sp|Q86VV8-4|RTTN_HUMAN Isoform 4 of Rotatin OS=Homo s 0.705753 5.13151 0.0783176 -5.89308 1.8269 5.8931 0.373795 -1.36961 0.895371 29.056 0.48807 0 8.61504E-07 101.14 0.705753 5.13151 0.0104628 68.406 0.347205 -2.05972 0.00954401 69.444 1 S PSPGSSSPRPSVV CDK1;GSK3;Polo box;Proline-directed 0.00405 8.61504E-07 101.14 _GTHHSQNPSPGSSpSPRPSVVGR_ GTHHSQNPSPGS(0.054)S(0.217)S(0.706)PRPS(0.023)VVGR GT(-68.41)HHS(-57.96)QNPS(-38.05)PGS(-11.13)S(-5.13)S(5.13)PRPS(-14.83)VVGR 14 3 770.02413 0.33803 182570 0 0 0 0 0 182570 0 1718 1185 47 47 1866 2108 17174 10358 Mix4_TiO2_1_3 2535 17174 10358 Mix4_TiO2_1_3 2535 Q86WH2;Q86WH2-2 Q86WH2 Q86WH2 >sp|Q86WH2|RASF3_HUMAN Ras association domain-containing protein 3 OS=Homo sapiens GN=RASSF3 PE=1 SV=1;>sp|Q86WH2-2|RASF3_HUMAN Isoform B of Ras association domain-containing protein 3 OS=Homo sapiens GN=RASSF3 0.590119 1.50844 0.590119 1.50844 0.0946066 43.436 0.5 0 0.488372 21.769 0.265663 -6.49601 0.100486 42.016 2 S KEKETHSYLSKEE 0.0946066 43.436 _ETHpSpYLSKEEIKEK_ ET(0.42)HS(0.59)Y(0.99)LSKEEIKEK ET(-1.51)HS(1.51)Y(17.62)LS(-37.21)KEEIKEK 4 2 940.90757 -1.6303 263080 165740 0 0 97341 0 0 0 1719 1190 36 36 5687 6477 55696 34136 Mix4_TiO2_Reinj_1_4 3800 55696 34136 Mix4_TiO2_Reinj_1_4 3800 Q86YD1 Q86YD1 Q86YD1 >sp|Q86YD1|PTOV1_HUMAN Prostate tumor-overexpressed gene 1 protein OS=Homo sapiens GN=PTOV1 PE=1 SV=1 0.987657 19.0338 0 0 0 0 0.987657 19.0338 0.0322664 52.669 1 S RAVRSRSWPASPR 14-3-3 binding;CAMK2;GSK3 0.0001701 0.0322664 52.669 _SRpSWPASPR_ S(0.012)RS(0.988)WPASPR S(-19.03)RS(19.03)WPAS(-52.67)PR 3 2 562.25585 -0.058536 188650 0 0 0 188650 0 0 0 1720 1191;1192 817;808 817 539 613 5049 3043 Mix4_TiO2_1_5 8097 5052 3046 Mix4_TiO2_Reinj_1_5 8817 Q86YS7;Q86YS7-2 Q86YS7;Q86YS7-2 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1;>sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 0.85175 7.59319 0.85175 7.59319 1.04191E-07 106.42 0.5 0 1.34083E-12 131.29 1 S KSLQRASTDNEEL PKA 0.042 1.34083E-12 131.29 _ApSTDNEELLQFPLELCSDSLPSHPFPPAK_ AS(0.852)T(0.148)DNEELLQFPLELCSDSLPSHPFPPAK AS(7.59)T(-7.59)DNEELLQFPLELCS(-91.26)DS(-91.26)LPS(-91.05)HPFPPAK 2 3 1107.1791 0.52874 1582300 265160 0 0 1317200 0 0 0 1721 1191;1192 260;260 260 3736 4214 35260 21798 Mix4_TiO2_1_5 5735 35260 21798 Mix4_TiO2_1_5 5735 Q86YS7;Q86YS7-2 Q86YS7;Q86YS7-2 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1;>sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 0.986227 18.5494 0.986227 18.5494 0.000132731 97.894 0 0 0.960246 13.83 0.00989896 73.259 1 S FLPACNSPSKEMK CDK1;CDK2;Proline-directed 0.0057 0.000132731 97.894 _LSSPAAFLPACNpSPSK_ LSSPAAFLPACNS(0.986)PS(0.014)K LS(-97.89)S(-97.89)PAAFLPACNS(18.55)PS(-18.55)K 13 2 863.89714 0.24641 1388000 410690 0 0 977300 0 0 0 1722 1191;1192 643;634 643 4092 4660 38710 23738 Mix4_TiO2_Reinj_1_5 8061 38710 23738 Mix4_TiO2_Reinj_1_5 8061 Q86YS7;Q86YS7-2 Q86YS7;Q86YS7-2 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1;>sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 1 101.682 0.999998 57.6748 0.000245174 88.5 1 101.682 5.59815E-18 148.02 1 S SEEIIGSPIPEPR Proline-directed 0.05 5.59815E-18 148.02 _NKELYEINPPEISEEIIGpSPIPEPR_ NKELYEINPPEISEEIIGS(1)PIPEPR NKELY(-148.02)EINPPEIS(-101.68)EEIIGS(101.68)PIPEPR 19 3 981.81775 0.36663 596050 127350 0 0 468700 0 0 0 1723 1191 293 293 4281 4872 40754 25085 Mix4_TiO2_Reinj_1_5 4444 40753 25084 Mix4_TiO2_1_5 3719 Q86YS7 Q86YS7 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1 0.918589 11.2986 0.0157227 -17.4991 0.00408143 69.269 0.918589 11.2986 0.236048 26.799 1 S LKNQTYSFSPSKS GSK3 0.081 0.00408143 69.269 _NQTYpSFSPSK_ NQT(0.002)Y(0.002)S(0.919)FS(0.068)PS(0.009)K NQT(-26.8)Y(-26.8)S(11.3)FS(-11.3)PS(-19.87)K 5 2 619.75809 0.20997 660230 0 0 0 660230 0 0 0 1724 1191 295 295 4281 4872 40753 25084 Mix4_TiO2_1_5 3719 40753 25084 Mix4_TiO2_1_5 3719 Q86YS7 Q86YS7 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1 0.883972 9.45136 0.883972 9.45136 0.00408143 69.269 0.0681177 -11.2986 0.236048 26.799 1 S NQTYSFSPSKSYS CDK1;CDK2;CK1;GSK3;Proline-directed 0.0057 0.00408143 69.269 _NQTYSFpSPSK_ NQTYS(0.016)FS(0.884)PS(0.1)K NQT(-67.6)Y(-52.74)S(-17.5)FS(9.45)PS(-9.45)K 7 2 619.75809 0.0018263 249750 249750 0 0 0 0 0 0 1725 1191 312 312 4745 5391 45281 27701 Mix4_TiO2_Reinj_1_5 4887 45281 27701 Mix4_TiO2_Reinj_1_5 4887 Q86YS7 Q86YS7 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1 0.636583 2.52393 0 0 0.636583 2.52393 0.101613 41.748 1 S SSDTDLSLTPKTG PLK1 0.033462 0.101613 41.748 _QSSSSDTDLpSLTPK_ QSSSSDT(0.007)DLS(0.637)LT(0.356)PK QS(-41.75)S(-41.75)S(-41.75)S(-35.42)DT(-19.53)DLS(2.52)LT(-2.52)PK 10 2 773.33763 1.163 91866 0 0 0 91866 0 0 0 1726 1191;1192 659;650 659 5639 6424;6425 55084 33706 Mix4_TiO2_Reinj_1_5 5244 55084 33706 Mix4_TiO2_Reinj_1_5 5244 Q86YS7;Q86YS7-2 Q86YS7;Q86YS7-2 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1;>sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 0.56255 1.10354 0.56255 1.10354 0.0219961 61.541 1 S RLLRSQSESSDEV CAMK2;CHK1;CHK1/2;PKA/AKT;PKD 0.00111111 0.0219961 61.541 _SQpSESSDEVTELDLSHGK_ S(0.436)QS(0.563)ES(0.001)SDEVTELDLSHGK S(-1.1)QS(1.1)ES(-27.9)S(-34.25)DEVT(-52.81)ELDLS(-61.54)HGK 3 2 1014.4257 2.2639 146170 0 0 0 146170 0 0 0 1727 1192 855 855 590 678 5609 3334 Mix4_TiO2_Reinj_1_6 4573 5608 3333 Mix4_TiO2_Reinj_1_5 5381 Q86YS7-2 Q86YS7-2 Q86YS7-2 >sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 0.886989 8.95457 0.0697099 -11.2532 0.0326568 55.857 0 0 0.886989 8.95457 0.0165613 61.38 0.210306 -5.746 0.0326569 55.857 0 0 1 S AAQRATSVDYSSF CAMK2;GSK3 0.002856 0.0165613 61.38 _ATpSVDYSSFADR_ AT(0.113)S(0.887)VDYSSFADR AT(-8.95)S(8.95)VDY(-41.91)S(-41.91)S(-41.91)FADR 3 2 699.7823 -0.11923 35678 0 0 0 35678 0 0 0 1728 1195 174 174 5367 6110 52205 31931 Mix4_TiO2_Reinj_1_5 8108 52204 31930 Mix4_TiO2_1_5 7361 Q8IVF7;Q8IVF7-3 Q8IVF7 Q8IVF7 >sp|Q8IVF7|FMNL3_HUMAN Formin-like protein 3 OS=Homo sapiens GN=FMNL3 PE=1 SV=3;>sp|Q8IVF7-3|FMNL3_HUMAN Isoform 3 of Formin-like protein 3 OS=Homo sapiens GN=FMNL3 1 81.3542 1 88.0556 7.14517E-11 119.87 1 81.3542 1.38294E-07 115.38 1 S LRSWSRSIEDLQP CK1;CK2 0.117 7.14517E-11 119.87 _pSIEDLQPPSALSAPFTNSLAR_ S(1)IEDLQPPSALSAPFTNSLAR S(81.35)IEDLQPPS(-81.35)ALS(-111.02)APFT(-115.38)NS(-115.38)LAR 1 2 1147.5568 0.87446 1077300 267800 0 0 809490 0 0 0 1729 1197 398 398 5448 6200 53142 32491 Mix4_TiO2_Reinj_1_3 7085 53142 32491 Mix4_TiO2_Reinj_1_3 7085 Q8IVH8;Q8IVH8-2;Q8IVH8-3 Q8IVH8 Q8IVH8 >sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3 PE=1 SV=1;>sp|Q8IVH8-2|M4K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3;>sp|Q8IVH8-3|M4K3_HUMAN 0.999999 59.1065 0.999996 53.9487 0.00185554 92.981 0.999999 59.1065 0.000288791 109.92 0.992316 21.1105 0.4183 21.111 0 0 1 S NKSLLKSVEEELH CK1;CK2;NEK6 0.076 0.000288791 109.92 _SLLKpSVEEELHQR_ SLLKS(1)VEEELHQR S(-59.11)LLKS(59.11)VEEELHQR 5 3 549.94158 -0.40462 683660 50003 0 0 598910 0 34742 0 1730 1197 329 329 6198 7080 61431 37244 Mix4_TiO2_Reinj_1_3 5080 61432 37245 Mix4_TiO2_Reinj_1_5 5114 Q8IVH8;Q8IVH8-2;Q8IVH8-3 Q8IVH8 Q8IVH8 >sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3 PE=1 SV=1;>sp|Q8IVH8-2|M4K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3;>sp|Q8IVH8-3|M4K3_HUMAN 0.984585 18.1269 0.594729 1.66579 0.0069919 69.82 0.984585 18.1269 0.00208934 106.09 0 0 0 0 1 S REEKTRSEITFGQ 0.00208934 106.09 _TRpSEITFGQVK_ T(0.015)RS(0.985)EITFGQVK T(-18.13)RS(18.13)EIT(-35.79)FGQVK 3 2 673.32922 0.025097 1059000 86565 0 0 972480 0 0 0 1731 1198 567 567 137 160 1433 900 Mix4_TiO2_1_5 5052 1433 900 Mix4_TiO2_1_5 5052 Q8IVT5;Q8IVT5-2;Q8IVT5-3 Q8IVT5 Q8IVT5 >sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1 PE=1 SV=2;>sp|Q8IVT5-2|KSR1_HUMAN Isoform 2 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1;>sp|Q8IVT5-3|KSR1_HUMAN Isoform 3 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KS 0.999814 40.319 0.999814 40.319 0.000660005 82.108 0 0 1 S EPEAGKSEAEDDE CK2 0.117 0.000660005 82.108 _ADVLEAHEAEAEEPEAGKpSEAEDDEDEVDDLPSSR_ ADVLEAHEAEAEEPEAGKS(1)EAEDDEDEVDDLPSSR ADVLEAHEAEAEEPEAGKS(40.32)EAEDDEDEVDDLPS(-40.32)S(-40.32)R 19 3 1288.5307 0.26848 419290 419290 0 0 0 0 0 0 1732 1198 404 404 5053;5973 5747;6813 58989 35789 Mix4_TiO2_Reinj_1_5 4775 58988 35788 Mix4_TiO2_1_5 4033 Q8IVT5;Q8IVT5-2;Q8IVT5-3 Q8IVT5 Q8IVT5 >sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1 PE=1 SV=2;>sp|Q8IVT5-2|KSR1_HUMAN Isoform 2 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1;>sp|Q8IVT5-3|KSR1_HUMAN Isoform 3 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KS 0.999482 34.4402 0.977425 17.504 0.00284326 82.989 0.999482 34.4402 0.0037263 79.226 0.691418 5.9115 0.098346 47.045 0 0 1 S RLRRTESVPSDIN CAMK2;CHK1;CHK1/2;PKD 0.002856 0.00284326 82.989 _TEpSVPSDINNPVDR_ TES(0.999)VPSDINNPVDR T(-34.44)ES(34.44)VPS(-38)DINNPVDR 3 2 811.85652 0.43421 493380 0.32189 103200 0 0 340900 0 49284 0 1733 1198 407 407 5053;5973 5747;6813 48861 29865 Mix4_TiO2_1_5 3875 58988 35788 Mix4_TiO2_1_5 4033 Q8IVT5;Q8IVT5-2;Q8IVT5-3 Q8IVT5 Q8IVT5 >sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1 PE=1 SV=2;>sp|Q8IVT5-2|KSR1_HUMAN Isoform 2 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1;>sp|Q8IVT5-3|KSR1_HUMAN Isoform 3 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KS 0.388138 1.03362 0.388138 1.03362 0.00284326 82.989 0.000158441 -37.9991 0.0037263 79.226 0.177252 -5.9115 0.098346 47.045 0 0 1 S RTESVPSDINNPV CK1 0.081 0.00284326 82.989 _RTESVPpSDINNPVDR_ RT(0.306)ES(0.306)VPS(0.388)DINNPVDR RT(-1.03)ES(-1.03)VPS(1.03)DINNPVDR 7 3 593.60715 -0.034822 0 0 0 0 0 0 0 0 0 1734 1198 309 309 5402 6148 52624 32168 Mix4_TiO2_Reinj_1_5 1824 52623 32167 Mix4_TiO2_Reinj_1_5 1819 Q8IVT5;Q8IVT5-2;Q8IVT5-3 Q8IVT5 Q8IVT5 >sp|Q8IVT5|KSR1_HUMAN Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1 PE=1 SV=2;>sp|Q8IVT5-2|KSR1_HUMAN Isoform 2 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1;>sp|Q8IVT5-3|KSR1_HUMAN Isoform 3 of Kinase suppressor of Ras 1 OS=Homo sapiens GN=KS 0.964205 14.4038 0 0 0.964205 14.4038 0.00502417 74.661 0 0 0 0 1 S TLTRSKSHESQLG CAMK2;CHK1;CHK1/2;CK1;PKD 0.003192 0.00502417 74.661 _SKpSHESQLGNR_ S(0.035)KS(0.964)HES(0.001)QLGNR S(-14.4)KS(14.4)HES(-30.72)QLGNR 3 3 441.53314 -0.51397 618770 0 0 0 618770 0 0 0 1735 1199 796 796 6554 7497 66286 40702 Mix4_TiO2_1_5 7045 66287 40703 Mix4_TiO2_Reinj_1_3 7974 Q8IWA0 Q8IWA0 Q8IWA0 >sp|Q8IWA0|WDR75_HUMAN WD repeat-containing protein 75 OS=Homo sapiens GN=WDR75 PE=1 SV=1 0.440933 0 0.440933 0 0.588059 30.31 0.429836 -0.737301 0.0905713 51.639 1 S EKVQDTSNTGLGE 0.0905713 51.639 _VQDTpSNTGLGEDIIHQLSK_ VQDT(0.092)S(0.441)NT(0.441)GLGEDIIHQLS(0.026)K VQDT(-6.8)S(0)NT(0)GLGEDIIHQLS(-12.3)K 5 3 712.33872 -0.51284 0 0 0 0 0 0 0 0 1736 1204 240 240 592 681 5647 3349 Mix4_TiO2_1_5 5681 5647 3349 Mix4_TiO2_1_5 5681 Q8IWW6;Q8IWW6-2;Q8IWW6-3 Q8IWW6 Q8IWW6 >sp|Q8IWW6|RHG12_HUMAN Rho GTPase-activating protein 12 OS=Homo sapiens GN=ARHGAP12 PE=1 SV=1;>sp|Q8IWW6-2|RHG12_HUMAN Isoform ARHGAP12a of Rho GTPase-activating protein 12 OS=Homo sapiens GN=ARHGAP12;>sp|Q8IWW6-3|RHG12_HUMAN Isoform 3 of Rho GTPase-activa 0.988018 19.1635 0.988018 19.1635 0.106795 52.371 0.88203 9.82037 1.63552 11.664 2 S NQGRPDSPVYANL CAMK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.106795 52.371 _ApTTPPNQGRPDpSPVYANLQELK_ AT(0.5)T(0.5)PPNQGRPDS(0.988)PVY(0.012)ANLQELK AT(0)T(0)PPNQGRPDS(19.16)PVY(-19.16)ANLQELK 12 3 852.72256 0.33349 816990 123810 0 0 693180 0 0 0 1737 1211 96 96 3268 3703 30879 19172 Mix4_TiO2_Reinj_1_6 4835 30879 19172 Mix4_TiO2_Reinj_1_6 4835 Q8IXM2 Q8IXM2 Q8IXM2 >sp|Q8IXM2|CQ049_HUMAN MLL1/MLL complex subunit C17orf49 OS=Homo sapiens GN=C17orf49 PE=1 SV=1 0.999994 52.1516 0 0 0.999994 52.1516 0.00869834 74.271 1 S IPLPAESPKKGPK CDK1;CDK2;Proline-directed 0.0057 0.00869834 74.271 _KVYEDSGIPLPAEpSPK_ KVYEDSGIPLPAES(1)PK KVY(-74.27)EDS(-52.15)GIPLPAES(52.15)PK 14 2 905.43715 0.31504 33861 0 0 0 33861 0 0 0 1738 1212 185 185 4786 5436 45667 27928 Mix4_TiO2_Reinj_1_6 6484 45667 27928 Mix4_TiO2_Reinj_1_6 6484 Q8IXM6 Q8IXM6 Q8IXM6 >sp|Q8IXM6|NRM_HUMAN Nurim OS=Homo sapiens GN=NRM PE=2 SV=1 1 70.4877 1 70.4877 0.0102197 70.488 1 S EPLALKSPRALRL CDK1;Proline-directed 0.0057 0.0102197 70.488 _QVYYHVLGLGEPLALKpSPR_ QVYYHVLGLGEPLALKS(1)PR QVY(-70.49)Y(-70.49)HVLGLGEPLALKS(70.49)PR 17 3 740.72407 0.1044 71368 0 0 0 71368 0 0 0 1739 1213 278 278 5683 6473 55686 34131 Mix4_TiO2_Reinj_1_5 6706 55686 34131 Mix4_TiO2_Reinj_1_5 6706 Q8IXT5 Q8IXT5 Q8IXT5 >sp|Q8IXT5|RB12B_HUMAN RNA-binding protein 12B OS=Homo sapiens GN=RBM12B PE=1 SV=2 0.590352 1.587 0.590352 1.587 0.0146902 64.784 1 S SPRRTRSRSPLGF CAMK2;PKA/AKT 0.00111111 0.0146902 64.784 _pSRSPLGFYVHLK_ S(0.59)RS(0.41)PLGFYVHLK S(1.59)RS(-1.59)PLGFY(-64.78)VHLK 1 3 495.25343 -0.65484 32742 0 0 0 32742 0 0 0 1740 1218 385 385 1257;4849 1417;5512 11845 7260 Mix4_TiO2_Reinj_1_3 7897 46515 28500 Mix4_TiO2_Reinj_1_3 7387 Q8IYU2;Q8IYU2-3 Q8IYU2 Q8IYU2 >sp|Q8IYU2|HACE1_HUMAN E3 ubiquitin-protein ligase HACE1 OS=Homo sapiens GN=HACE1 PE=1 SV=2;>sp|Q8IYU2-3|HACE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase HACE1 OS=Homo sapiens GN=HACE1 0.989995 19.954 0.0885131 -10.1219 0.181062 31.952 0.989995 19.954 1.26333E-05 139.37 1 S MKNKRDSTEITSI PKA 0.042 1.26333E-05 139.37 _DpSTEITSILLK_ DS(0.99)T(0.01)EITSILLK DS(19.95)T(-19.95)EIT(-76.25)S(-81.27)ILLK 2 2 650.32581 -0.28341 228170 0 0 0 228170 0 0 0 1741 1220 888 888 249 286 2486 1572 Mix4_TiO2_Reinj_1_5 6879 2485 1570 Mix4_TiO2_1_5 6132 Q8IZL8-2;Q8IZL8 Q8IZL8-2 Q8IZL8-2 >sp|Q8IZL8-2|PELP1_HUMAN Isoform 2 of Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens GN=PELP1;>sp|Q8IZL8|PELP1_HUMAN Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens GN=PELP1 PE=1 SV=2 0.487953 0 0.185672 -6.41479 9.13797E-05 92.743 0.487953 0 0.276476 53.603 1 S DPILAPSGTPPPT NEK6 0.076 9.13797E-05 92.743 _AGSNEDPILAPpSGTPPPTIPPDETFGGR_ AGS(0.001)NEDPILAPS(0.488)GT(0.488)PPPT(0.024)IPPDETFGGR AGS(-29.33)NEDPILAPS(0)GT(0)PPPT(-13.17)IPPDET(-52.78)FGGR 12 3 957.44632 0.33305 0 0 0 0 0 0 0 0 1742 1221 225 225 3462 3908 32582 20210 Mix4_InSol_TiO2_1 1610 32582 20210 Mix4_InSol_TiO2_1 1610 Q8IZP0;Q8IZP0-9;Q8IZP0-6;Q8IZP0-5;Q8IZP0-3;Q8IZP0-4;Q8IZP0-2;Q8IZP0-7;Q8IZP0-8;Q8IZP0-10 Q8IZP0 Q8IZP0 >sp|Q8IZP0|ABI1_HUMAN Abl interactor 1 OS=Homo sapiens GN=ABI1 PE=1 SV=4;>sp|Q8IZP0-9|ABI1_HUMAN Isoform 2 of Abl interactor 1 OS=Homo sapiens GN=ABI1;>sp|Q8IZP0-6|ABI1_HUMAN Isoform 6 of Abl interactor 1 OS=Homo sapiens GN=ABI1;>sp|Q8IZP0-5|ABI1_HUMAN Iso 0.999999 61.7673 0.951627 12.9386 0.599974 12.939 0 0 0.997544 26.0865 0.161677 34.361 0.999999 61.7673 0.0077615 61.767 0.999388 32.1261 0.0395091 50.376 1 S RLGSQHSPGRTAS CDK1;CDK2;CK1;Proline-directed 0.0057 0.0077615 61.767 _LGSQHpSPGR_ LGSQHS(1)PGR LGS(-61.77)QHS(61.77)PGR 6 2 509.72693 -0.018831 1956900 51057 0 0 1445100 0 212120 248590 1743 1223 392 392 1092 1228 10310 6354 Mix4_TiO2_Reinj_1_1 8159 10310 6354 Mix4_TiO2_Reinj_1_1 8159 Q8IZT6;Q8IZT6-2 Q8IZT6 Q8IZT6 >sp|Q8IZT6|ASPM_HUMAN Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM PE=1 SV=2;>sp|Q8IZT6-2|ASPM_HUMAN Isoform 2 of Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM 1 145.977 0.999993 54.7305 0.0209268 61.483 1 145.977 5.34187E-45 198.61 1 S SVNPILSPNQFLK Proline-directed 0.05 5.34187E-45 198.61 _DNYGLNQDLESESVNPILpSPNQFLK_ DNYGLNQDLESESVNPILS(1)PNQFLK DNY(-198.61)GLNQDLES(-151.36)ES(-145.98)VNPILS(145.98)PNQFLK 19 3 972.12173 0.45287 221310 0.8553 53986 0 0 167320 0 0 0 1744 1223 367 367 2838 3232 27111 16953 Mix4_TiO2_1_1 6154 27111 16953 Mix4_TiO2_1_1 6154 Q8IZT6;Q8IZT6-2 Q8IZT6 Q8IZT6 >sp|Q8IZT6|ASPM_HUMAN Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM PE=1 SV=2;>sp|Q8IZT6-2|ASPM_HUMAN Isoform 2 of Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM 0.999892 39.6527 0.999892 39.6527 0.0874842 39.653 0.924401 10.8735 0.661567 10.873 1 S IYQKILSPDSFIK Proline-directed 0.05 0.0874842 39.653 _ILpSPDSFIK_ ILS(1)PDSFIK ILS(39.65)PDS(-39.65)FIK 3 2 550.27539 0.1794 86943 16552 0 0 70391 0 0 0 1745 1223 446 446 2857 3254 27241 17034 Mix4_InSol_Tio2_Reinj_1 2257 27239 17032 Mix4_InSol_TiO2_1 2212 Q8IZT6;Q8IZT6-2 Q8IZT6 Q8IZT6 >sp|Q8IZT6|ASPM_HUMAN Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM PE=1 SV=2;>sp|Q8IZT6-2|ASPM_HUMAN Isoform 2 of Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM 0.997697 26.3672 0 0 0 0 0.986792 18.734 0.00535759 73.84 0.997697 26.3672 0.0271522 55.411 1 S ECQGSKSPKAIFE CDK1;Proline-directed 0.0057 0.00535759 73.84 _IPECQGSKpSPK_ IPECQGS(0.002)KS(0.998)PK IPECQGS(-26.37)KS(26.37)PK 9 3 437.53186 0.18276 521220 0 0 0 0 0 258970 262250 1746 1223 425 425 6532 7475 65983 40457 Mix4_TiO2_Reinj_1_1 4734 65983 40457 Mix4_TiO2_Reinj_1_1 4734 Q8IZT6;Q8IZT6-2 Q8IZT6 Q8IZT6 >sp|Q8IZT6|ASPM_HUMAN Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM PE=1 SV=2;>sp|Q8IZT6-2|ASPM_HUMAN Isoform 2 of Abnormal spindle-like microcephaly-associated protein OS=Homo sapiens GN=ASPM 1 67.0572 0.998246 30.5634 0.578304 30.563 1 67.0572 0.00752781 73.17 0.994072 25.2555 0.781789 25.255 0.972736 18.5343 1.03337 18.534 1 S NSQVPQSPEDWRK CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00752781 73.17 _VPLSNENSQVPQpSPEDWRK_ VPLSNENSQVPQS(1)PEDWRK VPLS(-73.17)NENS(-67.06)QVPQS(67.06)PEDWRK 13 3 764.02151 0.019623 501660 25415 0 0 273430 0 101150 101660 1747 1224 877 877 2524 2868;2869 23745 14744 Mix4_TiO2_1_1 3530 23750 14750 Mix4_TiO2_Reinj_1_1 3878 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.999996 54.2682 0.999996 54.2682 1.43057E-08 117.01 0.994512 26.0716 0.359207 49.384 0.999982 47.6094 3.0765E-18 147.87 0 0 0 0 0 0 1 S IHQAGGSPPASST GSK3;Proline-directed 0.05 3.0765E-18 147.87 _GVHIHQAGGpSPPASSTSSSSLTNDVAK_ GVHIHQAGGS(1)PPASSTSSSSLTNDVAK GVHIHQAGGS(54.27)PPAS(-71.4)S(-72.15)T(-54.27)S(-71.4)S(-82.8)S(-82.8)S(-82.8)LT(-98.12)NDVAK 10 3 891.41524 -0.49871 5965700 1415300 45641 0 4504700 0 0 0 1748 1224 884 884 2524 2868;2869 23747 14747 Mix4_TiO2_1_5 3916 23750 14750 Mix4_TiO2_Reinj_1_1 3878 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.226981 0 0.226981 0 1.43057E-08 117.01 0.00069366 -31.5646 0.359207 49.384 0.116261 -0.817449 3.0765E-18 147.87 0 0 0 0 0 0 1 S PPASSTSSSSLTN CK1 0.081 3.0765E-18 147.87 _GVHIHQAGGSPPASSTpSSSSLTNDVAK_ GVHIHQAGGS(0.207)PPAS(0.042)S(0.039)T(0.207)S(0.227)S(0.227)S(0.042)S(0.009)LTNDVAK GVHIHQAGGS(-0.4)PPAS(-7.3)S(-7.66)T(-0.4)S(0)S(0)S(-7.3)S(-14.25)LT(-28.59)NDVAK 17 4 668.81325 1.208 0 0 0 0 0 0 0 0 1749 1224 885 885 2524 2868;2869 23747 14747 Mix4_TiO2_1_5 3916 23750 14750 Mix4_TiO2_Reinj_1_1 3878 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.226981 0 0.226981 0 1.43057E-08 117.01 0.000626673 -32.0057 0.359207 49.384 0.127661 -0.411213 3.0765E-18 147.87 0 0 0 0 0 0 1 S PASSTSSSSLTND CK1 0.081 3.0765E-18 147.87 _GVHIHQAGGSPPASSTpSSSSLTNDVAK_ GVHIHQAGGS(0.207)PPAS(0.042)S(0.039)T(0.207)S(0.227)S(0.227)S(0.042)S(0.009)LTNDVAK GVHIHQAGGS(-0.4)PPAS(-7.3)S(-7.66)T(-0.4)S(0)S(0)S(-7.3)S(-14.25)LT(-28.59)NDVAK 18 4 668.81325 1.208 0 0 0 0 0 0 0 0 1750 1224 722 722 5854 6676 57749 35119 Mix4_InSol_Tio2_Reinj_1 4429 57748 35118 Mix4_InSol_TiO2_1 4506 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.985894 18.4736 0 0 0 0 0.980487 17.4031 0.0279275 54.043 0.982891 17.6239 0.0205278 56.387 0.985894 18.4736 0.0230351 55.592 1 S RLRSVSSYGNIRA CK1 0.081 0.0205278 56.387 _SVSpSYGNIR_ SVS(0.014)S(0.986)YGNIR S(-55.59)VS(-18.47)S(18.47)Y(-40.3)GNIR 4 2 531.73442 -0.47807 420550 0 0 0 305650 0 62686 52218 1751 1224 859 859 6466 7395;7396 65306 40048 Mix4_TiO2_1_5 4027 65306 40048 Mix4_TiO2_1_5 4027 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.999015 30.0907 0.999015 30.0907 4.8032E-40 233.29 3.32148E-10 -93.7387 1.95966E-15 145.54 0.972861 17.0478 7.47869E-16 152.4 0 0 1.08631E-07 -68.9739 7.76844E-26 184.23 0.00077674 -30.087 7.2337E-17 156.24 2 S TSSLTQSAPASPT CK1;GSK3;NEK6 0.076 4.8032E-40 233.29 _VLDTSSLTQpSAPApSPTNK_ VLDTSSLT(0.001)QS(0.999)APAS(0.953)PT(0.047)NK VLDT(-120.85)S(-88.93)S(-82.81)LT(-30.09)QS(30.09)APAS(13.05)PT(-13.05)NK 10 2 988.93432 0.68327 911250 336450 0 0 574800 0 0 0 1752 1224 863 863 6466 7395;7396 65291 40045 Mix4_TiO2_Reinj_1_5 4837 65291 40045 Mix4_TiO2_Reinj_1_5 4837 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.999635 35.1255 0.996752 24.8786 1.94105E-26 192.47 0.785601 5.63978 1.95966E-15 145.54 0.999635 35.1255 3.25175E-31 198.3 0 0 0.974469 15.817 7.76844E-26 184.23 0.792464 5.90091 7.2337E-17 156.24 1 S TQSAPASPTNKGV CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.25175E-31 198.3 _VLDTSSLTQSAPApSPTNK_ VLDTSSLTQSAPAS(1)PTNK VLDT(-102.78)S(-86.86)S(-78.75)LT(-45.38)QS(-45.38)APAS(35.13)PT(-35.13)NK 14 2 948.95115 -0.067028 6881100 1461300 76120 0 4919200 0 405460 18896 1753 1226 770 770 3504 3957 33072 20461 Mix4_TiO2_Reinj_1_5 2077 33067 20456 Mix4_InSol_TiO2_1 2276 Q8N1F7 Q8N1F7 Q8N1F7 >sp|Q8N1F7|NUP93_HUMAN Nuclear pore complex protein Nup93 OS=Homo sapiens GN=NUP93 PE=1 SV=2 0.314006 0 0 0 0.314006 0 0.150929 38.649 0.0066351 -21.5682 0.00511874 77.907 0.231553 -0.0303301 0.023704 60.305 1 S KGTSPSSSSRPQR CK1 0.081 0.00511874 77.907 _LKGTSPSpSSSRPQR_ LKGT(0.001)S(0.001)PS(0.056)S(0.314)S(0.314)S(0.314)RPQR LKGT(-24.1)S(-24.1)PS(-7.52)S(0)S(0)S(0)RPQR 8 2 784.38304 -0.19081 0 0 0 0 0 0 0 0 1754 1226 771 771 3504 3957 33072 20461 Mix4_TiO2_Reinj_1_5 2077 33067 20456 Mix4_InSol_TiO2_1 2276 Q8N1F7 Q8N1F7 Q8N1F7 >sp|Q8N1F7|NUP93_HUMAN Nuclear pore complex protein Nup93 OS=Homo sapiens GN=NUP93 PE=1 SV=2 0.314006 0 0 0 0.314006 0 0.150929 38.649 0.000199165 -36.7945 0.00511874 77.907 0.231553 -0.0303301 0.023704 60.305 1 S GTSPSSSSRPQRV CK1 0.143 0.00511874 77.907 _LKGTSPSpSSSRPQR_ LKGT(0.001)S(0.001)PS(0.056)S(0.314)S(0.314)S(0.314)RPQR LKGT(-24.1)S(-24.1)PS(-7.52)S(0)S(0)S(0)RPQR 9 2 784.38304 -0.19081 0 0 0 0 0 0 0 0 1755 1226 772 772 3504 3957 33072 20461 Mix4_TiO2_Reinj_1_5 2077 33067 20456 Mix4_InSol_TiO2_1 2276 Q8N1F7 Q8N1F7 Q8N1F7 >sp|Q8N1F7|NUP93_HUMAN Nuclear pore complex protein Nup93 OS=Homo sapiens GN=NUP93 PE=1 SV=2 0.314006 0 0 0 0.314006 0 0.150929 38.649 1.64812E-05 -47.6168 0.00511874 77.907 0.233176 0.0303301 0.023704 60.305 1 S TSPSSSSRPQRVI CK1 0.081 0.00511874 77.907 _LKGTSPSpSSSRPQR_ LKGT(0.001)S(0.001)PS(0.056)S(0.314)S(0.314)S(0.314)RPQR LKGT(-24.1)S(-24.1)PS(-7.52)S(0)S(0)S(0)RPQR 10 2 784.38304 -0.19081 0 0 0 0 0 0 0 0 1756 1227 772 772 302 344 2819 1732 Mix4_TiO2_Reinj_1_5 2421 2819 1732 Mix4_TiO2_Reinj_1_5 2421 Q8N1F8 Q8N1F8 Q8N1F8 >sp|Q8N1F8|S11IP_HUMAN Serine/threonine-protein kinase 11-interacting protein OS=Homo sapiens GN=STK11IP PE=1 SV=3 0.999886 42.4486 0.999886 42.4486 0.0800188 42.449 1 S LDRAKNSPPQAPS Proline-directed 0.05 0.0800188 42.449 _AKNpSPPQAPSTR_ AKNS(1)PPQAPSTR AKNS(42.45)PPQAPS(-42.45)T(-42.45)R 4 2 667.31664 0.1593 190740 0 0 0 190740 0 0 0 1757 1227 398 398 4811 5461 45907 28069 Mix4_TiO2_Reinj_1_5 3692 45907 28069 Mix4_TiO2_Reinj_1_5 3692 Q8N1F8;Q8N1F8-2 Q8N1F8 Q8N1F8 >sp|Q8N1F8|S11IP_HUMAN Serine/threonine-protein kinase 11-interacting protein OS=Homo sapiens GN=STK11IP PE=1 SV=3;>sp|Q8N1F8-2|S11IP_HUMAN Isoform 2 of Serine/threonine-protein kinase 11-interacting protein OS=Homo sapiens GN=STK11IP 0.999862 38.601 0.998354 27.8277 6.27294E-07 120.28 0.999862 38.601 5.78657E-07 121.61 1 S VRVRRASISEPSD AURORA;AURORA-1;AURORA-A;CAMK2;CK2;PKA;PKA/AKT 0.00111111 5.78657E-07 121.61 _RApSISEPSDTDPEPR_ RAS(1)ISEPSDTDPEPR RAS(38.6)IS(-38.6)EPS(-88.03)DT(-113.98)DPEPR 3 2 868.87799 0.071992 360740 92344 0 0 268400 0 0 0 1758 1228 1778 1778 614;615 707;708 5823 3438 Mix4_TiO2_1_1 4486 5823 3438 Mix4_TiO2_1_1 4486 Q8N1I0-3;Q8N1I0;Q8N1I0-4 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-4|DOCK4_HUMAN Isoform 4 of Dedicator of cytokinesis pr 0.940442 15.2885 0.940442 15.2885 4.89626E-07 124.06 0 0 0.570761 3.53615 1.53963E-05 115.05 0.927989 15.0206 0.0220402 61.502 0 0 1 S PTPSSWSLDSGKE CK1 0.081 4.89626E-07 124.06 _AVNPTPSSWpSLDSGK_ AVNPTPS(0.003)S(0.028)WS(0.94)LDS(0.028)GK AVNPT(-33.28)PS(-24.34)S(-15.29)WS(15.29)LDS(-15.29)GK 10 2 813.36398 0.55394 464590 71725 0 0 321790 0 71074 0 1759 1228 1906 1906 1818 2052 16668 10030 Mix4_TiO2_1_5 4110 16667 10029 Mix4_TiO2_1_1 3774 Q8N1I0-3;Q8N1I0;Q8N1I0-2;Q8N1I0-4 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-2|DOCK4_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.499897 0 0.499897 0 0.129556 38.607 0 0 0.19271 -0.752356 0.948433 2.9684 0 0 0 0 0 0 1 S EPVRKESKTPPPY CAMK2;PKA 0.004788 0.129556 38.607 _EpSKTPPPYSVYER_ ES(0.5)KT(0.5)PPPYSVYER ES(0)KT(0)PPPY(-38.61)S(-38.61)VY(-38.61)ER 2 3 544.91503 0.29036 0 0 0 0 0 0 0 0 1760 1228 1817 1817 2678;2679 3050;3051;3052 25144 15538 Mix4_TiO2_1_1 1522 25147 15542 Mix4_TiO2_Reinj_1_5 2303 Q8N1I0-3;Q8N1I0;Q8N1I0-2;Q8N1I0-4 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-2|DOCK4_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.982259 18.3913 0.982259 18.3913 0.145563 36.071 0.962558 14.1645 0.00411344 62.971 0 0 0.962461 14.0913 0.0296388 56.712 0.967526 15.1982 0.0187744 59.788 1 S RHTTSVSPSPAGR CK1;Proline-directed 0.05 0.00411344 62.971 _HTTSVpSPSPAGR_ HTT(0.001)S(0.002)VS(0.982)PS(0.014)PAGR HT(-36.07)T(-28.45)S(-27.21)VS(18.39)PS(-18.39)PAGR 6 2 638.78772 -0.60981 427390 67963 0 0 0 0 171970 187460 1761 1228 1819 1819 2678;2679 3050;3051;3052 25161 15546 Mix4_TiO2_Reinj_1_1 2842 25147 15542 Mix4_TiO2_Reinj_1_5 2303 Q8N1I0-3;Q8N1I0;Q8N1I0-2;Q8N1I0-4 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-2|DOCK4_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.881204 9.41282 0.337888 0.426452 1.39658 0.42645 0.881204 9.41282 0.00411344 62.971 0 0 0.0375189 -14.0913 0.0296388 56.712 0.0292307 -15.1982 0.0187744 59.788 1 S TTSVSPSPAGRSP CK1;Proline-directed 0.05 0.00411344 62.971 _HTTSVSPpSPAGRSPLK_ HT(0.001)T(0.001)S(0.001)VS(0.015)PS(0.881)PAGRS(0.101)PLK HT(-29.31)T(-29.31)S(-29.31)VS(-17.74)PS(9.41)PAGRS(-9.41)PLK 8 2 851.41963 -0.1654 178330 0 0 0 178330 0 0 0 1762 1228 1824 1824 2679 3051;3052 25160 15545 Mix4_TiO2_Reinj_1_1 2832 25160 15545 Mix4_TiO2_Reinj_1_1 2832 Q8N1I0-3;Q8N1I0;Q8N1I0-2;Q8N1I0-4 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-2|DOCK4_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.999853 38.7075 0.337888 0.426452 1.39658 0.42645 0.999853 38.7075 0.036017 58.594 0 0 0 0 1 S PSPAGRSPLKGSV CDK1;CDK2;Proline-directed 0.0057 0.036017 58.594 _HTTSVSPSPAGRpSPLK_ HTTSVSPSPAGRS(1)PLK HT(-58.59)T(-58.59)S(-58.02)VS(-51.01)PS(-38.71)PAGRS(38.71)PLK 13 3 567.94884 -0.0051167 519620 0 0 0 519620 0 0 0 1763 1228 1629 1629 4292 4883 40816 25118 Mix4_TiO2_1_1 1822 40818 25122 Mix4_TiO2_Reinj_1_1 2369 Q8N1I0-3;Q8N1I0;Q8N1I0-2 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-2|DOCK4_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.990504 20.2928 0.990504 20.2928 0.000360415 107.46 0 0 0.985469 18.3527 3.96151E-06 142.89 0 0 0.987534 19.1966 0.000812534 97.864 0.647438 2.64629 3.19966E-05 126.18 1 S SAPASVSPDGTRV Proline-directed 0.05 3.96151E-06 142.89 _NSAPASVpSPDGTR_ NSAPASVS(0.991)PDGT(0.009)R NS(-107.46)APAS(-36.22)VS(20.29)PDGT(-20.29)R 8 2 669.78791 -0.14305 1751600 218770 0 0 723690 0 428660 380470 1764 1228 1640 1640 5043 5736 48770 29811 Mix4_TiO2_Reinj_1_5 4594 48770 29811 Mix4_TiO2_Reinj_1_5 4594 Q8N1I0-3;Q8N1I0;Q8N1I0-2 Q8N1I0-3 Q8N1I0-3 >sp|Q8N1I0-3|DOCK4_HUMAN Isoform 3 of Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4;>sp|Q8N1I0|DOCK4_HUMAN Dedicator of cytokinesis protein 4 OS=Homo sapiens GN=DOCK4 PE=1 SV=3;>sp|Q8N1I0-2|DOCK4_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.867624 8.18854 0 0 0.867624 8.18854 0.0258274 55.804 1 S RVIPRRSPLSYPA PKA;Proline-directed 0.042 0.0258274 55.804 _RpSPLSYPAVNR_ RS(0.868)PLS(0.132)Y(0.001)PAVNR RS(8.19)PLS(-8.19)Y(-30.88)PAVNR 2 2 670.32955 -0.0064199 173250 0 0 0 173250 0 0 0 1765 1229 1318 1318 1256;4848 1416;5511 46509 28499 Mix4_TiO2_Reinj_1_5 1480 46509 28499 Mix4_TiO2_Reinj_1_5 1480 Q8N201 Q8N201 Q8N201 >sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 0.988213 19.2344 0.988213 19.2344 0.131676 35.448 0.00422232 -22.9217 0.634547 30.673 0 0 1 S LPPRRDSTEAPKP CAMK2;PKA 0.004788 0.131676 35.448 _RDpSTEAPKPK_ RDS(0.988)T(0.012)EAPKPK RDS(19.23)T(-19.23)EAPKPK 3 3 403.52722 -0.078703 729950 0 0 0 729950 0 0 0 1766 1229 1327 1327 1256;5721 1416;6519 56170 34348 Mix4_TiO2_2_2 2021 56168 34344 Mix4_TiO2_1_1 1908 Q8N201 Q8N201 Q8N201 >sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 0.924695 10.8917 0.605419 1.85919 0.00254765 81.464 0.924695 10.8917 0.564735 26.411 0.601285 1.78418 0.00694458 72.571 0 0 0.827411 6.94161 0.634547 30.673 0 0 1 S APKPKSSPEQPIG Polo box;Proline-directed 0.00405 0.00254765 81.464 _SpSPEQPIGQGR_ S(0.075)S(0.925)PEQPIGQGR S(-10.89)S(10.89)PEQPIGQGR 2 2 618.27444 -0.63578 1751600 263040 11033 0 1249800 0 227680 0 1767 1229 82 82 3746 4226 35413 21884 Mix4_TiO2_1_1 4798 35415 21887 Mix4_TiO2_Reinj_1_1 5590 Q8N201 Q8N201 Q8N201 >sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 0.587709 1.70875 0.587709 1.70875 0.0454707 52.23 0 0 0.498971 0.122142 0.00804348 76.766 0 0 0 0 0 0 1 S KRPKLSSTPPLSA 0.00804348 76.766 _LSpSTPPLSALGR_ LS(0.016)S(0.588)T(0.397)PPLSALGR LS(-15.72)S(1.71)T(-1.71)PPLS(-51.01)ALGR 3 2 639.82631 0.19465 49682 49682 0 0 0 0 0 0 1768 1229 307 307 6330 7236;7237 63765 39096 Mix4_TiO2_Reinj_1_1 6805 63765 39096 Mix4_TiO2_Reinj_1_1 6805 Q8N201 Q8N201 Q8N201 >sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 0.990408 21.9032 0.970266 19.6474 0.226094 72.447 0 0 0.990408 21.9032 0.00942661 80.114 0 0 0 0 1 S IAEEKLSPEQEGQ Proline-directed 0.05 0.00942661 80.114 _VAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLpSPEQEGQLM(ox)PR_ VAGDLGAGSSPHPSLT(0.001)EEEDS(0.002)QT(0.006)ELLIAEEKLS(0.99)PEQEGQLMPR VAGDLGAGS(-44.16)S(-43.36)PHPS(-33.63)LT(-32.7)EEEDS(-26.62)QT(-21.9)ELLIAEEKLS(21.9)PEQEGQLMPR 33 4 1168.5468 -0.36598 922490 136740 0 0 785750 0 0 0 1769 1232 110 110 5277 6005 51218 31384 Mix4_TiO2_1_6 2442 51219 31385 Mix4_TiO2_Reinj_1_6 3037 Q8N2U9 Q8N2U9 Q8N2U9 >sp|Q8N2U9|PQLC1_HUMAN PQ-loop repeat-containing protein 1 OS=Homo sapiens GN=PQLC1 PE=2 SV=1 0.99992 40.9496 0.99992 40.9496 0.000105648 116.21 0.999826 37.5896 3.49073E-05 124.95 1 S LNARRRSFTAADS AURORA;AURORA-A;CAMK2;PKA;PKA/AKT 0.00111111 3.49073E-05 124.95 _pSFTAADSKDEEVK_ S(1)FTAADSKDEEVK S(40.95)FT(-40.95)AADS(-110.75)KDEEVK 1 2 753.82162 -0.18126 445330 121530 0 0 323800 0 0 0 1770 1237 732 732 2498;2499 2838;2839 23511 14620 Mix4_TiO2_Reinj_1_5 4446 23503 14616 Mix4_TiO2_Reinj_1_5 4730 Q8N4C8 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2 0.956033 13.3767 0.445204 -0.955744 0.00372107 76.662 0 0 0.956033 13.3767 0.000312387 85.631 0.818483 7.03853 0.0093242 71.719 0.499207 0 1.04263 33.038 1 S PGPPNASSNPDLR 0.000312387 85.631 _GTPKPPGPPAQPPGPPNApSSNPDLRR_ GTPKPPGPPAQPPGPPNAS(0.956)S(0.044)NPDLRR GT(-44.77)PKPPGPPAQPPGPPNAS(13.38)S(-13.38)NPDLRR 19 3 894.77645 0.17497 1449700 0 0 0 1102800 0 346920 0 1771 1237 733 733 2498;2499 2838;2839 23503 14616 Mix4_TiO2_Reinj_1_5 4730 23503 14616 Mix4_TiO2_Reinj_1_5 4730 Q8N4C8 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2 0.5586 1.02268 0.554796 0.955744 0.00372107 76.662 0 0 0.5586 1.02268 0.000312387 85.631 0.259311 -4.55815 0.0093242 71.719 0.499207 0 1.04263 33.038 1 S GPPNASSNPDLRR CK2 0.117 0.000312387 85.631 _GTPKPPGPPAQPPGPPNASpSNPDLR_ GTPKPPGPPAQPPGPPNAS(0.441)S(0.559)NPDLR GT(-85.63)PKPPGPPAQPPGPPNAS(-1.02)S(1.02)NPDLR 20 3 842.74274 0.16598 788980 87671 0 0 701310 0 0 0 1772 1237 641 641 4665 5294 44198 27066 Mix4_TiO2_1_1 4706 44198 27066 Mix4_TiO2_1_1 4706 Q8N4C8;Q8N4C8-3;Q8N4C8-2 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2;>sp|Q8N4C8-3|MINK1_HUMAN Isoform MiNK-2 of Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1;>sp|Q8N4C8-2|MINK1_HUMAN Isoform MiNK-1 of Misshapen-like kinase 1 OS=Homo sapiens 0.999502 33.9276 0.999502 33.9276 0.000213192 85.15 0.99924 31.3253 0.000264617 81.848 1 S AVIRQNSDPTSEG CAMK2;CHK1;GSK3;PKD 0.020748 0.000213192 85.15 _QNpSDPTSEGPGPSPNPPAWVRPDNEAPPK_ QNS(1)DPTSEGPGPSPNPPAWVRPDNEAPPK QNS(33.93)DPT(-33.93)S(-40.58)EGPGPS(-52.08)PNPPAWVRPDNEAPPK 3 3 1040.1349 0.078918 1116400 379150 0 0 737290 0 0 0 1773 1237 763 763 5188 5906 50239 30712 Mix4_TiO2_1_5 4721 50242 30717 Mix4_TiO2_Reinj_1_5 5400 Q8N4C8;Q8N4C8-3;Q8N4C8-2 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2;>sp|Q8N4C8-3|MINK1_HUMAN Isoform MiNK-2 of Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1;>sp|Q8N4C8-2|MINK1_HUMAN Isoform MiNK-1 of Misshapen-like kinase 1 OS=Homo sapiens 1 68.8972 1 68.8972 0.000423617 87.204 0 0 1 67.3563 6.79566E-11 131.46 0.999666 35.0911 0.117739 49.051 0.999855 43.1561 0.170377 43.156 1 S HLPQAGSLERNRV 6.79566E-11 131.46 _SDSVLPASHGHLPQAGpSLER_ SDSVLPASHGHLPQAGS(1)LER S(-87.2)DS(-87.2)VLPAS(-68.9)HGHLPQAGS(68.9)LER 17 3 713.33906 -0.94721 4347000 624600 0 0 1746600 0 1034200 941610 1774 1237 699 699 5517 6281 53853 32939 Mix4_TiO2_Reinj_1_5 7225 53853 32939 Mix4_TiO2_Reinj_1_5 7225 Q8N4C8 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2 0.934675 11.5558 0.934493 11.5429 0.000204346 140.06 0 0 0.934675 11.5558 0.000124004 146.59 0.930017 11.235 0.00272627 121.99 0 0 1 S VRARPRSNSAWQI CAMK2;PKA/AKT 0.001764 0.000124004 146.59 _pSNSAWQIYLQR_ S(0.935)NS(0.065)AWQIYLQR S(11.56)NS(-11.56)AWQIY(-135)LQR 1 2 723.33229 0.095508 719220 149180 0 0 451020 0 119020 0 1775 1237 701 701 5517 6281 53851 32937 Mix4_TiO2_1_1 6043 53853 32939 Mix4_TiO2_Reinj_1_5 7225 Q8N4C8 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2 0.713041 3.95294 0.713041 3.95294 0.000204346 140.06 0 0 0.0653252 -11.5558 0.000124004 146.59 0.069983 -11.235 0.00272627 121.99 0 0 1 S ARPRSNSAWQIYL CAMK2;PKA/AKT 0.001764 0.000124004 146.59 _SNpSAWQIYLQR_ S(0.287)NS(0.713)AWQIYLQR S(-3.95)NS(3.95)AWQIY(-78.25)LQR 3 2 723.33229 -0.089742 50600 50600 0 0 0 0 0 0 1776 1237 601 601 5646 6432 55137 33743 Mix4_TiO2_Reinj_1_5 2631 55134 33740 Mix4_TiO2_1_5 2006 Q8N4C8;Q8N4C8-3;Q8N4C8-2 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2;>sp|Q8N4C8-3|MINK1_HUMAN Isoform MiNK-2 of Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1;>sp|Q8N4C8-2|MINK1_HUMAN Isoform MiNK-1 of Misshapen-like kinase 1 OS=Homo sapiens 0.985488 18.3191 0.98498 18.1674 0.00288979 104.99 0 0 0.985488 18.3191 0.00150387 77.218 0.984884 18.1394 0.00217409 75.151 0.813029 6.38336 0.0119147 58.611 1 S PVPRSQSLQDQPT CAMK2;CHK1;CK2;PKD 0.020748 0.00288979 104.99 _SQpSLQDQPTR_ S(0.015)QS(0.985)LQDQPTR S(-18.32)QS(18.32)LQDQPT(-77.22)R 3 2 620.2719 -0.12561 836850 106980 0 0 425330 0 164670 139870 1777 1239 264 264 1421 1595 13242 8132 Mix4_TiO2_Reinj_1_5 4118 13242 8132 Mix4_TiO2_Reinj_1_5 4118 Q8N556 Q8N556 Q8N556 >sp|Q8N556|AFAP1_HUMAN Actin filament-associated protein 1 OS=Homo sapiens GN=AFAP1 PE=1 SV=2 0.516093 0.279667 0 0 0 0 0.516093 0.279667 7.06834E-07 101.63 1 S ECPPPPSSPVHKA 7.06834E-07 101.63 _EAYSGCSGPVDSECPPPPpSSPVHK_ EAYSGCSGPVDSECPPPPS(0.516)S(0.484)PVHK EAY(-101.63)S(-97.1)GCS(-79.15)GPVDS(-58.27)ECPPPPS(0.28)S(-0.28)PVHK 19 3 874.36098 -0.52989 148100 0 0 0 148100 0 0 0 1778 1239 668 668 5339 6080 51857 31745 Mix4_TiO2_1_5 3433 51857 31745 Mix4_TiO2_1_5 3433 Q8N556 Q8N556 Q8N556 >sp|Q8N556|AFAP1_HUMAN Actin filament-associated protein 1 OS=Homo sapiens GN=AFAP1 PE=1 SV=2 0.999998 59.0733 0.999998 59.0733 0.00131878 98.182 0.999836 40.2699 0.00659667 79.379 0 0 0.995947 26.3855 0.0366683 54.722 1 S GTSSPQSPVFRHR CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00131878 98.182 _SGTSSPQpSPVFR_ SGTSSPQS(1)PVFR S(-82.61)GT(-90.61)S(-59.07)S(-60.51)PQS(59.07)PVFR 8 2 665.29537 0.81456 443100 113770 0 0 231240 0 0 98091 1779 1241 331 331 3941;4396 4488;5001 37383 22981 Mix4_TiO2_1_4 1804 37380 22975 Mix4_InSol_Tio2_Reinj_1 2594 Q8N5G2 Q8N5G2 Q8N5G2 >sp|Q8N5G2|MACOI_HUMAN Macoilin OS=Homo sapiens GN=TMEM57 PE=1 SV=1 0.874599 8.44579 0.874599 8.44579 1.73827E-07 163.85 0 0 0.239128 -5.02681 1.73827E-07 163.85 0.0997028 -9.55592 0.122112 36.997 0.0186264 -17.2171 1.58601E-07 164.91 0.0269524 -15.5742 5.80698E-12 176.23 1 S ASGVVNSSPRSHS GSK3 0.081 5.80698E-12 176.23 _NASGVVNpSSPR_ NASGVVNS(0.875)S(0.125)PR NAS(-34.52)GVVNS(8.45)S(-8.45)PR 8 2 584.26133 0.24064 9421.6 9421.6 0 0 0 0 0 0 1780 1241 332 332 3941;4396 4488;5001 37382 22979 Mix4_TiO2_1_3 1768 37380 22975 Mix4_InSol_Tio2_Reinj_1 2594 Q8N5G2 Q8N5G2 Q8N5G2 >sp|Q8N5G2|MACOI_HUMAN Macoilin OS=Homo sapiens GN=TMEM57 PE=1 SV=1 0.983119 17.652 0.983119 17.652 1.73827E-07 163.85 0 0 0.974889 15.891 1.73827E-07 163.85 0.900118 9.55592 0.122112 36.997 0.981374 17.2171 1.58601E-07 164.91 0.975573 16.014 5.80698E-12 176.23 1 S SGVVNSSPRSHSA CDK1;Polo box;Proline-directed 0.00405 5.80698E-12 176.23 _NASGVVNSpSPR_ NASGVVNS(0.017)S(0.983)PR NAS(-93.88)GVVNS(-17.65)S(17.65)PR 9 2 584.26133 0.21581 1545500 183970 0 0 863530 8036.7 248010 241910 1781 1242 245 245 2813 3205 26911 16819 Mix4_TiO2_Reinj_1_2 3100 26910 16818 Mix4_TiO2_Reinj_1_2 2107 Q8N5Y8-3;Q8N5Y8;Q8N5Y8-2 Q8N5Y8-3 Q8N5Y8-3 >sp|Q8N5Y8-3|PAR16_HUMAN Isoform 3 of Poly [ADP-ribose] polymerase 16 OS=Homo sapiens GN=PARP16;>sp|Q8N5Y8|PAR16_HUMAN Poly [ADP-ribose] polymerase 16 OS=Homo sapiens GN=PARP16 PE=2 SV=2;>sp|Q8N5Y8-2|PAR16_HUMAN Isoform 2 of Poly [ADP-ribose] polymerase 16 1 51.3297 1 51.3297 0.0247518 58.095 1 S RARIKHSEGGDIP 0.0247518 58.095 _IKHpSEGGDIPPK_ IKHS(1)EGGDIPPK IKHS(51.33)EGGDIPPK 4 3 453.2219 0.088941 62675 0 0 0 62675 0 0 0 1782 1243 65 65 159 186 1749 1196 Mix4_TiO2_1_6 4283 1749 1196 Mix4_TiO2_1_6 4283 Q8N6S5 Q8N6S5 Q8N6S5 >sp|Q8N6S5|AR6P6_HUMAN ADP-ribosylation factor-like protein 6-interacting protein 6 OS=Homo sapiens GN=ARL6IP6 PE=1 SV=1 0.999977 46.3998 0.999977 46.3998 0.0660627 46.4 0 0 1 S FSAGAWSEPRKRS 0.0660627 46.4 _AEFSAGAWpSEPR_ AEFSAGAWS(1)EPR AEFS(-46.4)AGAWS(46.4)EPR 9 2 694.28755 -0.072425 8077.5 8077.5 0 0 0 0 0 0 1783 1245 83 83 6503 7440 65681 40277 Mix4_TiO2_Reinj_1_3 2680 65681 40277 Mix4_TiO2_Reinj_1_3 2680 Q8N8A6 Q8N8A6 Q8N8A6 >sp|Q8N8A6|DDX51_HUMAN ATP-dependent RNA helicase DDX51 OS=Homo sapiens GN=DDX51 PE=1 SV=3 1 106.275 1 68.1718 0.0158847 68.172 1 106.275 5.79604E-05 106.27 1 77.252 0.00552404 77.252 1 75.6428 0.00736013 75.643 1 S NDAEPGSPEAPQG ERK/MAPK;Proline-directed 0.0025 5.79604E-05 106.27 _VNDAEPGpSPEAPQGK_ VNDAEPGS(1)PEAPQGK VNDAEPGS(106.27)PEAPQGK 8 2 788.33797 0.12633 498060 80708 0 0 285560 0 75341 56451 1784 1247 347 347 2188 2476 20081 12372 Mix4_TiO2_Reinj_1_4 3017 20081 12372 Mix4_TiO2_Reinj_1_4 3017 Q8N9K5 Q8N9K5 Q8N9K5 >sp|Q8N9K5|ZN565_HUMAN Zinc finger protein 565 OS=Homo sapiens GN=ZNF565 PE=2 SV=1 0.499972 0 0.499724 0 0.172902 29.575 0 0 0.499972 0 0.0573461 39.566 1 S GKGFIHSSEVTRH 0.0573461 39.566 _GFIHpSSEVTR_ GFIHS(0.5)S(0.5)EVTR GFIHS(0)S(0)EVT(-39.57)R 5 2 606.77408 0.26859 0 0 0 0 0 0 0 0 1785 1247 348 348 2188 2476 20081 12372 Mix4_TiO2_Reinj_1_4 3017 20081 12372 Mix4_TiO2_Reinj_1_4 3017 Q8N9K5 Q8N9K5 Q8N9K5 >sp|Q8N9K5|ZN565_HUMAN Zinc finger protein 565 OS=Homo sapiens GN=ZNF565 PE=2 SV=1 0.499972 0 0.499724 0 0.172902 29.575 0 0 0.499972 0 0.0573461 39.566 1 S KGFIHSSEVTRHQ 0.0573461 39.566 _GFIHpSSEVTR_ GFIHS(0.5)S(0.5)EVTR GFIHS(0)S(0)EVT(-39.57)R 6 2 606.77408 0.26859 0 0 0 0 0 0 0 0 1786 1248 445 445 2533 2878 23796 14776 Mix4_TiO2_1_1 6226 23796 14776 Mix4_TiO2_1_1 6226 Q8NB49;Q8NB49-4;Q8NB49-3;Q8NB49-2 Q8NB49 Q8NB49 >sp|Q8NB49|AT11C_HUMAN Probable phospholipid-transporting ATPase IG OS=Homo sapiens GN=ATP11C PE=1 SV=3;>sp|Q8NB49-4|AT11C_HUMAN Isoform 4 of Probable phospholipid-transporting ATPase IG OS=Homo sapiens GN=ATP11C;>sp|Q8NB49-3|AT11C_HUMAN Isoform 3 of Proba 0.982462 17.484 0.982462 17.484 4.30467E-11 126.84 0 0 1 S QEVDGLSQTDGTL CK2 0.117 4.30467E-11 126.84 _GVTQEVDGLpSQTDGTLTYFDK_ GVTQEVDGLS(0.982)QT(0.018)DGTLTYFDK GVT(-61.53)QEVDGLS(17.48)QT(-17.48)DGT(-58.04)LT(-63.73)Y(-92.54)FDK 10 2 1177.5254 1.0416 41333 41333 0 0 0 0 0 0 1787 1251 540 540 6698 7670 67979 41729 Mix4_TiO2_Reinj_1_5 8449 67978 41728 Mix4_TiO2_Reinj_1_1 8099 Q8NBN3;Q8NBN3-3 Q8NBN3 Q8NBN3 >sp|Q8NBN3|TM87A_HUMAN Transmembrane protein 87A OS=Homo sapiens GN=TMEM87A PE=1 SV=3;>sp|Q8NBN3-3|TM87A_HUMAN Isoform 3 of Transmembrane protein 87A OS=Homo sapiens GN=TMEM87A 1 85.2219 1 86.8293 2.54042E-07 110.05 0.99019 23.7507 1.33569 27.073 1 85.2219 1.95535E-25 159.61 1 S LPALLDSDEERMI CK2;NEK6 0.076 1.95535E-25 159.61 _WVEENVPSSVTDVALPALLDpSDEER_ WVEENVPSSVTDVALPALLDS(1)DEER WVEENVPS(-102.57)S(-102.57)VT(-85.22)DVALPALLDS(85.22)DEER 21 3 950.77421 0.2699 970870 440580 23913 0 506370 0 0 0 1788 1255 497 497 6696 7667 67916 41699 Mix4_TiO2_Reinj_1_4 4411 67915 41698 Mix4_TiO2_1_4 3920 Q8NC56 Q8NC56 Q8NC56 >sp|Q8NC56|LEMD2_HUMAN LEM domain-containing protein 2 OS=Homo sapiens GN=LEMD2 PE=1 SV=1 0.548533 1.77101 0.190999 -6.24606 0.0101226 73.01 0.548533 1.77101 0.0116434 70.263 0 0 0 0 1 S RWTKPSSFSDSER CK1;CK2;GSK3 0.081 0.0101226 73.01 _WTKPSpSFSDSER_ WTKPS(0.086)S(0.549)FS(0.365)DSER WT(-70.26)KPS(-8.03)S(1.77)FS(-1.77)DS(-32.81)ER 6 2 753.81667 0.3429 249120 0 0 0 249120 0 0 0 1789 1255 499 499 6696 7667 67915 41698 Mix4_TiO2_1_4 3920 67915 41698 Mix4_TiO2_1_4 3920 Q8NC56 Q8NC56 Q8NC56 >sp|Q8NC56|LEMD2_HUMAN LEM domain-containing protein 2 OS=Homo sapiens GN=LEMD2 PE=1 SV=1 0.804707 6.24606 0.804707 6.24606 0.0101226 73.01 0.36484 -1.77101 0.0116434 70.263 0 0 0 0 1 S TKPSSFSDSER__ CK1;CK2 0.081 0.0101226 73.01 _WTKPSSFpSDSER_ WTKPS(0.004)S(0.191)FS(0.805)DS(0.001)ER WT(-73.01)KPS(-23.43)S(-6.25)FS(6.25)DS(-30.98)ER 8 2 753.81667 -0.40588 33341 33341 0 0 0 0 0 0 1790 1256 473 473 2225 2518 20446 12545 Mix4_TiO2_Reinj_1_3 5539 20446 12545 Mix4_TiO2_Reinj_1_3 5539 Q8NCD3;Q8NCD3-2;Q8NCD3-3 Q8NCD3 Q8NCD3 >sp|Q8NCD3|HJURP_HUMAN Holliday junction recognition protein OS=Homo sapiens GN=HJURP PE=1 SV=2;>sp|Q8NCD3-2|HJURP_HUMAN Isoform 2 of Holliday junction recognition protein OS=Homo sapiens GN=HJURP;>sp|Q8NCD3-3|HJURP_HUMAN Isoform 3 of Holliday junction rec 1 103.736 1 103.736 7.02715E-05 103.74 1 71.6458 0.0119209 71.646 0.999984 48.0856 0.092433 48.086 1 S YRGGPASPGGLQG ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 7.02715E-05 103.74 _GGPApSPGGLQGLETR_ GGPAS(1)PGGLQGLETR GGPAS(103.74)PGGLQGLET(-103.74)R 5 2 738.84576 -0.70319 437650 0 0 0 282920 0 73280 81453 1791 1259 216 216 5598 6380 54759 33532 Mix4_TiO2_Reinj_1_3 3523 54760 33533 Mix4_TiO2_Reinj_1_4 3529 Q8ND56;Q8ND56-2 Q8ND56 Q8ND56 >sp|Q8ND56|LS14A_HUMAN Protein LSM14 homolog A OS=Homo sapiens GN=LSM14A PE=1 SV=3;>sp|Q8ND56-2|LS14A_HUMAN Isoform AlphaSNBP(B) of Protein LSM14 homolog A OS=Homo sapiens GN=LSM14A 0.995074 26.2497 0.964879 17.4085 0.0913912 44.176 0 0 0.995074 26.2497 0.00142744 91.538 0 0 0 0 1 S AAVGRRSPVSTRP PKA;Proline-directed 0.042 0.00142744 91.538 _pSPVSTRPLPSASQK_ S(0.995)PVS(0.002)T(0.002)RPLPSASQK S(26.25)PVS(-26.25)T(-26.25)RPLPS(-39.84)AS(-39.84)QK 1 2 767.88489 0.59802 973740 208280 0 0 765460 0 0 0 1792 1260 324 324 5112 5815 49408 30139 Mix4_TiO2_Reinj_1_4 5232 49405 30134 Mix4_TiO2_1_2 3685 Q8ND76;Q8ND76-2;Q8ND76-3 Q8ND76 Q8ND76 >sp|Q8ND76|CCNY_HUMAN Cyclin-Y OS=Homo sapiens GN=CCNY PE=1 SV=2;>sp|Q8ND76-2|CCNY_HUMAN Isoform a of Cyclin-Y OS=Homo sapiens GN=CCNY;>sp|Q8ND76-3|CCNY_HUMAN Isoform 3 of Cyclin-Y OS=Homo sapiens GN=CCNY 0.5 0 0.239931 -5.00435 0.00237151 87.068 0.5 0 0.00523673 74.138 0.107002 -8.67764 0.574896 8.8073 0 0 1 S RSARKRSASADNL CAMK2;PKA 0.004788 0.00237151 87.068 _pSASADNLTLPR_ S(0.5)AS(0.5)ADNLTLPR S(0)AS(0)ADNLT(-67.7)LPR 1 2 612.78464 0.34261 343370 0 0 0 343370 0 0 0 1793 1260 326 326 5112 5815 49405 30134 Mix4_TiO2_1_2 3685 49405 30134 Mix4_TiO2_1_2 3685 Q8ND76;Q8ND76-2;Q8ND76-3 Q8ND76 Q8ND76 >sp|Q8ND76|CCNY_HUMAN Cyclin-Y OS=Homo sapiens GN=CCNY PE=1 SV=2;>sp|Q8ND76-2|CCNY_HUMAN Isoform a of Cyclin-Y OS=Homo sapiens GN=CCNY;>sp|Q8ND76-3|CCNY_HUMAN Isoform 3 of Cyclin-Y OS=Homo sapiens GN=CCNY 0.993402 21.7773 0.993402 21.7773 0.00237151 87.068 0.5 0 0.00523673 74.138 0.789143 8.67764 0.574896 8.8073 0 0 1 S ARKRSASADNLTL CAMK2;PKA;PKA/AKT 0.001764 0.00237151 87.068 _SApSADNLTLPR_ S(0.007)AS(0.993)ADNLTLPR S(-21.78)AS(21.78)ADNLT(-70.47)LPR 3 2 612.78464 -0.055663 469900 79520 0 0 343370 0 47005 0 1794 1261 15 15 5154 5868 49982 30554 Mix4_TiO2_Reinj_1_2 6603 49982 30554 Mix4_TiO2_Reinj_1_2 6603 Q8NDC0 Q8NDC0 Q8NDC0 >sp|Q8NDC0|MISSL_HUMAN MAPK-interacting and spindle-stabilizing protein-like OS=Homo sapiens GN=MAPK1IP1L PE=1 SV=4 1 155.583 1 116.453 4.23703E-09 125.84 1 155.583 1.36948E-16 170.75 1 144.802 2.59427E-14 156.39 1 133.73 2.31444E-36 143.63 1 S DALPEHSPAKTSA CDK1;CDK2;Proline-directed 0.0057 1.36948E-16 170.75 _(ac)SDEFSLADALPEHpSPAK_ SDEFSLADALPEHS(1)PAK S(-170.75)DEFS(-155.58)LADALPEHS(155.58)PAK 14 2 968.42223 0.27682 578230 130680 0 0 273430 0 174120 0 1795 1262 609 609 6259 7150 62334 37934 Mix4_InSol_TiO2_1 2376 62334 37934 Mix4_InSol_TiO2_1 2376 Q8NDT2 Q8NDT2 Q8NDT2 >sp|Q8NDT2|RB15B_HUMAN Putative RNA-binding protein 15B OS=Homo sapiens GN=RBM15B PE=1 SV=3 0.975091 16.0407 0 0 0 0 0.975091 16.0407 0.0826378 39.998 0 0 1 S RGRTTHSPYEERS CK2;Proline-directed 0.05 0.0826378 39.998 _TTHpSPYEER_ TTHS(0.975)PY(0.024)EER T(-35.33)T(-34.35)HS(16.04)PY(-16.04)EER 4 2 600.24007 -0.020725 29035 0 0 0 0 0 29035 0 1796 1263 1585 1585 3374 3815 31782 19686 Mix4_TiO2_Reinj_1_1 8048 31782 19686 Mix4_TiO2_Reinj_1_1 8048 Q8NDV7;Q8NDV7-5;Q8NDV7-6;Q8NDV7-2;Q8NDV7-3 Q8NDV7 Q8NDV7 >sp|Q8NDV7|TNR6A_HUMAN Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens GN=TNRC6A PE=1 SV=2;>sp|Q8NDV7-5|TNR6A_HUMAN Isoform 5 of Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens GN=TNRC6A;>sp|Q8NDV7-6|TNR6A_HUMAN Isoform 6 of 0.988712 19.5359 0.92601 11.2281 0.529344 51.108 0 0 0.988712 19.5359 0.000316118 81.334 1 S SSTSPASPPGSIG CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.000316118 81.334 _LEESPFVPYDFM(ox)NSSTSPApSPPGSIGDGWPR_ LEESPFVPYDFMNSSTSPAS(0.989)PPGS(0.011)IGDGWPR LEES(-76.01)PFVPY(-59.45)DFMNS(-53.08)S(-46.69)T(-46.69)S(-36.2)PAS(19.54)PPGS(-19.54)IGDGWPR 20 3 1140.8304 -0.13754 164220 59414 0 0 104800 0 0 0 1797 1263 739 739 4670 5300 44272 27086 Mix4_TiO2_1_5 3566 44272 27086 Mix4_TiO2_1_5 3566 Q8NDV7;Q8NDV7-5;Q8NDV7-6;Q8NDV7-2 Q8NDV7 Q8NDV7 >sp|Q8NDV7|TNR6A_HUMAN Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens GN=TNRC6A PE=1 SV=2;>sp|Q8NDV7-5|TNR6A_HUMAN Isoform 5 of Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens GN=TNRC6A;>sp|Q8NDV7-6|TNR6A_HUMAN Isoform 6 of 0.872148 8.43865 0.872148 8.43865 0.0569411 48.982 0 0 1 S AWDTETSPRGERK CDK1;Proline-directed 0.0057 0.0569411 48.982 _QNTAWDTETpSPR_ QNTAWDT(0.003)ET(0.125)S(0.872)PR QNT(-48.98)AWDT(-24.79)ET(-8.44)S(8.44)PR 10 2 743.30393 0.45833 46218 46218 0 0 0 0 0 0 1798 1263 943 943 5516 6280 53847 32935 Mix4_TiO2_Reinj_1_1 5401 53846 32934 Mix4_TiO2_1_5 5223 Q8NDV7;Q8NDV7-5;Q8NDV7-6;Q8NDV7-2 Q8NDV7 Q8NDV7 >sp|Q8NDV7|TNR6A_HUMAN Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens GN=TNRC6A PE=1 SV=2;>sp|Q8NDV7-5|TNR6A_HUMAN Isoform 5 of Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens GN=TNRC6A;>sp|Q8NDV7-6|TNR6A_HUMAN Isoform 6 of 0.873551 8.40721 0.86497 8.13139 1.50109E-23 156.7 0.873551 8.40721 7.14118E-07 104 0 0 1 S SSKPVSSPDWNKQ ERK/MAPK;Polo box;Proline-directed 0.0034 1.50109E-23 156.7 _SNQSLGWGDSSKPVSpSPDWNK_ SNQSLGWGDSSKPVS(0.126)S(0.874)PDWNK S(-104)NQS(-94.47)LGWGDS(-50.1)S(-33.58)KPVS(-8.41)S(8.41)PDWNK 16 3 786.0129 0.21189 732740 416240 0 0 316500 0 0 0 1799 1264 109 109 3752 4232 35465 21905 Mix4_TiO2_Reinj_1_5 5134 35465 21905 Mix4_TiO2_Reinj_1_5 5134 Q8NE71;Q8NE71-2 Q8NE71 Q8NE71 >sp|Q8NE71|ABCF1_HUMAN ATP-binding cassette sub-family F member 1 OS=Homo sapiens GN=ABCF1 PE=1 SV=2;>sp|Q8NE71-2|ABCF1_HUMAN Isoform 2 of ATP-binding cassette sub-family F member 1 OS=Homo sapiens GN=ABCF1 0.8544 7.73406 0 0 0.8544 7.73406 0.146843 43.335 1 S KLSVPTSDEEDEV CK1;CK2 0.117 0.146843 43.335 _LSVPTpSDEEDEVPAPKPR_ LS(0.002)VPT(0.144)S(0.854)DEEDEVPAPKPR LS(-27.18)VPT(-7.73)S(7.73)DEEDEVPAPKPR 6 3 682.65242 -0.37199 80206 0 0 0 80206 0 0 0 1800 1267 723 723 1732 1949;1950 15903 9624 Mix4_TiO2_1_5 5947 15903 9624 Mix4_TiO2_1_5 5947 Q8NEL9;Q8NEL9-2;Q8NEL9-3 Q8NEL9 Q8NEL9 >sp|Q8NEL9|DDHD1_HUMAN Phospholipase DDHD1 OS=Homo sapiens GN=DDHD1 PE=2 SV=2;>sp|Q8NEL9-2|DDHD1_HUMAN Isoform 2 of Phospholipase DDHD1 OS=Homo sapiens GN=DDHD1;>sp|Q8NEL9-3|DDHD1_HUMAN Isoform 3 of Phospholipase DDHD1 OS=Homo sapiens GN=DDHD1 0.997556 26.9984 0.997556 26.9984 3.10764E-07 108.25 0.74452 4.3452 0.000331082 84.84 1 S GISTIPSPVTSPV CK1;GSK3;Proline-directed 0.05 3.10764E-07 108.25 _EPTSVSENEGISTIPpSPVTSPVLSR_ EPTSVSENEGISTIPS(0.998)PVT(0.002)SPVLSR EPT(-99.56)S(-104.13)VS(-100.3)ENEGIS(-96.01)T(-96.01)IPS(27)PVT(-27)S(-33.48)PVLS(-53.07)R 16 3 888.4319 0.20281 196710 196710 0 0 0 0 0 0 1801 1267 727 727 1732 1949;1950 15899 9622 Mix4_TiO2_1_5 5870 15900 9623 Mix4_TiO2_Reinj_1_5 6542 Q8NEL9;Q8NEL9-2;Q8NEL9-3 Q8NEL9 Q8NEL9 >sp|Q8NEL9|DDHD1_HUMAN Phospholipase DDHD1 OS=Homo sapiens GN=DDHD1 PE=2 SV=2;>sp|Q8NEL9-2|DDHD1_HUMAN Isoform 2 of Phospholipase DDHD1 OS=Homo sapiens GN=DDHD1;>sp|Q8NEL9-3|DDHD1_HUMAN Isoform 3 of Phospholipase DDHD1 OS=Homo sapiens GN=DDHD1 0.791846 6.57999 0.791846 6.57999 0.0189031 63.268 0.71541 6.02408 0.000331082 84.84 2 S IPSPVTSPVLSRR CK1;ERK/MAPK;GSK3;Proline-directed 0.0034 0.000331082 84.84 _EPTSVSENEGISTIPpSPVTpSPVLSR_ EPTSVSENEGISTIPS(0.971)PVT(0.196)S(0.792)PVLS(0.041)R EPT(-63.27)S(-63.27)VS(-62.65)ENEGIS(-47.56)T(-52.21)IPS(14.61)PVT(-6.58)S(6.58)PVLS(-13.01)R 20 3 915.08734 0.42941 1020500 232710 0 0 787830 0 0 0 1802 1268 54 54 953 1073 8996 5494 Mix4_TiO2_Reinj_1_1 4102 8996 5494 Mix4_TiO2_Reinj_1_1 4102 Q8NEM2 Q8NEM2 Q8NEM2 >sp|Q8NEM2|SHCBP_HUMAN SHC SH2 domain-binding protein 1 OS=Homo sapiens GN=SHCBP1 PE=1 SV=3 0.494393 0 0.492998 0 0.128455 41.601 0 0 0.494393 0 0.0524406 55.285 0 0 0.492064 0 0.391624 30.439 0.493954 0 0.286087 34.714 1 S YRDKPGSSLQSFM GSK3 0.081 0.0524406 55.285 _DKPGpSSLQSFMPEGK_ DKPGS(0.494)S(0.494)LQS(0.011)FMPEGK DKPGS(0)S(0)LQS(-16.44)FMPEGK 5 2 844.3735 1.3257 0 0 0 0 0 0 0 0 0 1803 1268 55 55 953 1073 8996 5494 Mix4_TiO2_Reinj_1_1 4102 8996 5494 Mix4_TiO2_Reinj_1_1 4102 Q8NEM2 Q8NEM2 Q8NEM2 >sp|Q8NEM2|SHCBP_HUMAN SHC SH2 domain-binding protein 1 OS=Homo sapiens GN=SHCBP1 PE=1 SV=3 0.494393 0 0.492998 0 0.128455 41.601 0 0 0.494393 0 0.0524406 55.285 0 0 0.492064 0 0.391624 30.439 0.493954 0 0.286087 34.714 1 S RDKPGSSLQSFMP 0.0524406 55.285 _DKPGpSSLQSFMPEGK_ DKPGS(0.494)S(0.494)LQS(0.011)FMPEGK DKPGS(0)S(0)LQS(-16.44)FMPEGK 6 2 844.3735 1.3257 0 0 0 0 0 0 0 0 0 1804 1270 133 133 1087 1222 10263 6328 Mix4_InSol_Tio2_Reinj_1 5915 10263 6328 Mix4_InSol_Tio2_Reinj_1 5915 Q8NEY8;Q8NEY8-3;Q8NEY8-2;Q8NEY8-8;Q8NEY8-6;Q8NEY8-5 Q8NEY8 Q8NEY8 >sp|Q8NEY8|PPHLN_HUMAN Periphilin-1 OS=Homo sapiens GN=PPHLN1 PE=1 SV=2;>sp|Q8NEY8-3|PPHLN_HUMAN Isoform 3 of Periphilin-1 OS=Homo sapiens GN=PPHLN1;>sp|Q8NEY8-2|PPHLN_HUMAN Isoform 2 of Periphilin-1 OS=Homo sapiens GN=PPHLN1;>sp|Q8NEY8-8|PPHLN_HUMAN Isofo 0.999261 31.3095 0 0 0.987389 18.9375 0.212284 30.667 0 0 0.999261 31.3095 0.0664431 46.292 1 S NTFFRESPVGRKD PKA;Proline-directed 0.042 0.0664431 46.292 _DNTFFREpSPVGR_ DNT(0.001)FFRES(0.999)PVGR DNT(-31.31)FFRES(31.31)PVGR 8 2 752.83265 1.6041 316750 0 0 0 230370 0 0 86385 1805 1270 205 205 1288 1453 12090 7413 Mix4_InSol_TiO2_1 1898 12090 7413 Mix4_InSol_TiO2_1 1898 Q8NEY8;Q8NEY8-3;Q8NEY8-2;Q8NEY8-8;Q8NEY8-6;Q8NEY8-5;Q8NEY8-7 Q8NEY8 Q8NEY8 >sp|Q8NEY8|PPHLN_HUMAN Periphilin-1 OS=Homo sapiens GN=PPHLN1 PE=1 SV=2;>sp|Q8NEY8-3|PPHLN_HUMAN Isoform 3 of Periphilin-1 OS=Homo sapiens GN=PPHLN1;>sp|Q8NEY8-2|PPHLN_HUMAN Isoform 2 of Periphilin-1 OS=Homo sapiens GN=PPHLN1;>sp|Q8NEY8-8|PPHLN_HUMAN Isofo 0.997532 26.161 0 0 0 0 0.978705 21.2674 0.332811 29.538 0.997532 26.161 0.00505736 77.965 0.67822 6.63962 0.0313181 58.444 1 S KTSRDTSPSSGSA CAMK2;CK1;Proline-directed 0.042 0.00505736 77.965 _DTpSPSSGSAVSSSK_ DT(0.002)S(0.998)PSSGSAVSSSK DT(-26.16)S(26.16)PS(-43.07)S(-54.59)GS(-62.38)AVS(-77.97)S(-77.97)S(-77.97)K 3 2 688.78249 0.34726 265690 0 0 0 73787 0 88046 103860 1806 1271 625 625 4584 5205 43349 26572 Mix4_TiO2_1_4 4522 43349 26572 Mix4_TiO2_1_4 4522 Q8NEZ4-3;Q8NEZ4 Q8NEZ4-3 Q8NEZ4-3 >sp|Q8NEZ4-3|MLL3_HUMAN Isoform 3 of Histone-lysine N-methyltransferase MLL3 OS=Homo sapiens GN=MLL3;>sp|Q8NEZ4|MLL3_HUMAN Histone-lysine N-methyltransferase MLL3 OS=Homo sapiens GN=MLL3 PE=1 SV=3 0.999009 30.0362 0.999009 30.0362 0.072442 44.593 0 0 1 S ISNEVDSEDLKMS 0.072442 44.593 _QISNEVDpSEDLK_ QIS(0.001)NEVDS(0.999)EDLK QIS(-30.04)NEVDS(30.04)EDLK 8 2 728.81379 0.47034 148340 148340 0 0 0 0 0 0 1807 1272 8358 8358 5406 6153 52698 32209 Mix4_TiO2_1_1 3366 52698 32209 Mix4_TiO2_1_1 3366 Q8NF91;Q8NF91-4;Q8NF91-2;Q8NF91-8;Q8NF91-3;Q8NF91-9 Q8NF91 Q8NF91 >sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3;>sp|Q8NF91-4|SYNE1_HUMAN Isoform 4 of Nesprin-1 OS=Homo sapiens GN=SYNE1;>sp|Q8NF91-2|SYNE1_HUMAN Isoform Beta of Nesprin-1 OS=Homo sapiens GN=SYNE1;>sp|Q8NF91-8|SYNE1_HUMAN Isoform Beta 2 0.876828 8.61791 0.876828 8.61791 1.36376E-06 123.14 0 0 0.866485 8.14009 7.9658E-06 117.55 0 0 0 0 0 0 1 S TENIIRSKTPTGP 1.36376E-06 123.14 _pSKTPTGPELDTSYK_ S(0.877)KT(0.121)PT(0.003)GPELDTSYK S(8.62)KT(-8.62)PT(-25.22)GPELDT(-101.82)S(-106.28)Y(-123.14)K 1 2 802.36619 -0.93628 252970 40501 0 0 212470 0 0 0 1808 1273 1421 1421 3741 4220 35347 21862 Mix4_TiO2_1_5 2225 35349 21864 Mix4_TiO2_Reinj_1_5 2830 Q8NFA0 Q8NFA0 Q8NFA0 >sp|Q8NFA0|UBP32_HUMAN Ubiquitin carboxyl-terminal hydrolase 32 OS=Homo sapiens GN=USP32 PE=1 SV=1 0.550734 1.43753 0.550734 1.43753 0.0779001 43.048 0 0 0.411806 0.999906 0.0304728 56.476 1 S GSKNKLSSSKENL 0.0304728 56.476 _LpSSSKENLDASK_ LS(0.551)S(0.396)S(0.054)KENLDASK LS(1.44)S(-1.44)S(-10.11)KENLDAS(-43.05)K 2 2 679.8136 -0.13534 152460 152460 0 0 0 0 0 0 1809 1273 1422 1422 3741 4220 35349 21864 Mix4_TiO2_Reinj_1_5 2830 35349 21864 Mix4_TiO2_Reinj_1_5 2830 Q8NFA0 Q8NFA0 Q8NFA0 >sp|Q8NFA0|UBP32_HUMAN Ubiquitin carboxyl-terminal hydrolase 32 OS=Homo sapiens GN=USP32 PE=1 SV=1 0.468819 0 0.395538 -1.43753 0.0779001 43.048 0 0 0.468819 0 0.0304728 56.476 1 S SKNKLSSSKENLD CK2 0.117 0.0304728 56.476 _LSpSSKENLDASK_ LS(0.062)S(0.469)S(0.469)KENLDASK LS(-8.76)S(0)S(0)KENLDAS(-56.48)K 3 2 679.8136 0.15446 0 0 0 0 0 0 0 0 1810 1273 1423 1423 3741 4220 35349 21864 Mix4_TiO2_Reinj_1_5 2830 35349 21864 Mix4_TiO2_Reinj_1_5 2830 Q8NFA0 Q8NFA0 Q8NFA0 >sp|Q8NFA0|UBP32_HUMAN Ubiquitin carboxyl-terminal hydrolase 32 OS=Homo sapiens GN=USP32 PE=1 SV=1 0.468819 0 0.053701 -10.1096 0.0779001 43.048 0 0 0.468819 0 0.0304728 56.476 1 S KNKLSSSKENLDA NEK6 0.076 0.0304728 56.476 _LSpSSKENLDASK_ LS(0.062)S(0.469)S(0.469)KENLDASK LS(-8.76)S(0)S(0)KENLDAS(-56.48)K 4 2 679.8136 0.15446 0 0 0 0 0 0 0 0 1811 1275 106 106 487 552 4529 2738 Mix4_TiO2_Reinj_1_4 2600 4529 2738 Mix4_TiO2_Reinj_1_4 2600 Q8NFF5;Q8NFF5-2;Q8NFF5-3 Q8NFF5 Q8NFF5 >sp|Q8NFF5|FAD1_HUMAN FAD synthase OS=Homo sapiens GN=FLAD1 PE=1 SV=1;>sp|Q8NFF5-2|FAD1_HUMAN Isoform 2 of FAD synthase OS=Homo sapiens GN=FLAD1;>sp|Q8NFF5-3|FAD1_HUMAN Isoform 3 of FAD synthase OS=Homo sapiens GN=FLAD1 0.99998 47.0364 0.99998 47.0364 0.0836466 47.036 1 S SRASELSPGRSVT CDK1;CDK2;CK1;GSK3;Proline-directed 0.0057 0.0836466 47.036 _ASELpSPGR_ ASELS(1)PGR AS(-47.04)ELS(47.04)PGR 5 2 448.69731 0.32426 0 0 0 0 0 0 0 0 1812 1276 62 62 259 296 2528 1595 Mix4_TiO2_Reinj_1_3 2938 2528 1595 Mix4_TiO2_Reinj_1_3 2938 Q8NFG4;Q8NFG4-2;Q8NFG4-3 Q8NFG4 Q8NFG4 >sp|Q8NFG4|FLCN_HUMAN Folliculin OS=Homo sapiens GN=FLCN PE=1 SV=1;>sp|Q8NFG4-2|FLCN_HUMAN Isoform 2 of Folliculin OS=Homo sapiens GN=FLCN;>sp|Q8NFG4-3|FLCN_HUMAN Isoform 3 of Folliculin OS=Homo sapiens GN=FLCN 1 72.3689 0.99997 45.1635 0.000812219 88.981 0 0 1 72.3689 0.000149295 97.089 0 0 1 S SRMRAHSPAEGAS CAMK2;CK2;PKA/AKT;Proline-directed 0.001764 0.000149295 97.089 _AHpSPAEGASVESSSPGPK_ AHS(1)PAEGASVESSSPGPK AHS(72.37)PAEGAS(-72.37)VES(-97.09)S(-97.09)S(-97.09)PGPK 3 2 887.88581 0.99458 356410 60985 0 0 295430 0 0 0 1813 1276 302 302 3293 3728 31113 19279 Mix4_TiO2_1_3 6260 31113 19279 Mix4_TiO2_1_3 6260 Q8NFG4 Q8NFG4 Q8NFG4 >sp|Q8NFG4|FLCN_HUMAN Folliculin OS=Homo sapiens GN=FLCN PE=1 SV=1 0.996427 24.6412 0.996427 24.6412 7.46146E-05 95.258 0 0 1 S SESWDNSEAEEEE CK1;CK2 0.117 7.46146E-05 95.258 _LADLEEESESWDNpSEAEEEEKAPVLPESTEGR_ LADLEEESES(0.003)WDNS(0.996)EAEEEEKAPVLPESTEGR LADLEEES(-38.2)ES(-24.64)WDNS(24.64)EAEEEEKAPVLPES(-76.54)T(-76.54)EGR 14 3 1228.8581 -0.10214 156080 156080 0 0 0 0 0 0 1814 1279 22 22 6223 7109 61638 37356 Mix4_TiO2_1_4 3392 61638 37356 Mix4_TiO2_1_4 3392 Q8NFU5 Q8NFU5 Q8NFU5 >sp|Q8NFU5|IPMK_HUMAN Inositol polyphosphate multikinase OS=Homo sapiens GN=IPMK PE=1 SV=1 0.57728 1.35335 0.57728 1.35335 1.0702E-06 113.35 0 0 0.563522 1.10952 0.000424142 91.631 0 0 0.547282 0.825672 0.15076 44.238 1 S PPEMRTSPAIEST PKA;Proline-directed 0.042 1.0702E-06 113.35 _TpSPAIESTPEGTPQPAGGR_ T(0.423)S(0.577)PAIESTPEGTPQPAGGR T(-1.35)S(1.35)PAIES(-69.16)T(-82.38)PEGT(-106.35)PQPAGGR 2 2 966.93858 0.82806 791770 199250 0 0 572370 0 0 20149 1815 1280 670 670 4432 5042 42148 25967 Mix4_TiO2_Reinj_1_5 6854 42148 25967 Mix4_TiO2_Reinj_1_5 6854 Q8NI08;Q8NI08-2 Q8NI08 Q8NI08 >sp|Q8NI08|NCOA7_HUMAN Nuclear receptor coactivator 7 OS=Homo sapiens GN=NCOA7 PE=1 SV=2;>sp|Q8NI08-2|NCOA7_HUMAN Isoform 2 of Nuclear receptor coactivator 7 OS=Homo sapiens GN=NCOA7 0.876555 8.51936 0 0 0.762583 5.31393 0.816977 24.366 0.876555 8.51936 0.050075 56.62 1 S GKPMRKSFATHTA AURORA;NIMA;PKA 0.001741464 0.050075 56.62 _PMRKpSFATHTAAM(ox)VQQYGK_ PMRKS(0.877)FAT(0.123)HTAAMVQQYGK PMRKS(8.52)FAT(-8.52)HT(-37.09)AAMVQQY(-56.62)GK 5 2 1124.5238 -0.85081 666720 0 99677 0 567040 0 0 0 1816 1281 1417 1417 2726;3063 3106;3483 25756 15913 Mix4_TiO2_Reinj_1_5 2605 25756 15913 Mix4_TiO2_Reinj_1_5 2605 Q8NI27;Q8NI27-2 Q8NI27 Q8NI27 >sp|Q8NI27|THOC2_HUMAN THO complex subunit 2 OS=Homo sapiens GN=THOC2 PE=1 SV=2;>sp|Q8NI27-2|THOC2_HUMAN Isoform 2 of THO complex subunit 2 OS=Homo sapiens GN=THOC2 0.984337 21.4992 0 0 0.984337 21.4992 0.0872476 45.16 0 0 0 0 1 S KIDTHPSPSHSST GSK3;Proline-directed 0.05 0.0872476 45.16 _IDTHPpSPSHSSTVK_ IDTHPS(0.984)PS(0.005)HS(0.007)S(0.002)T(0.002)VK IDT(-45.16)HPS(21.5)PS(-22.75)HS(-21.5)S(-27.57)T(-27.57)VK 6 3 524.90664 0.58893 639990 0 0 0 639990 0 0 0 1817 1285 427 427 619;2978 714;3387 28362 17611 Mix4_TiO2_Reinj_1_2 3551 5902 3472 Mix4_TiO2_Reinj_1_2 3907 Q8TB61;Q8TB61-2;Q8TB61-3 Q8TB61 Q8TB61 >sp|Q8TB61|S35B2_HUMAN Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens GN=SLC35B2 PE=1 SV=1;>sp|Q8TB61-2|S35B2_HUMAN Isoform 2 of Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens GN=SLC35B2;>sp|Q8TB61-3|S35B2_HUMAN 1 79.2831 1 47.6264 0.0617292 47.626 1 53.5462 0.0334414 53.546 1 79.2831 0.00267911 83.644 0 0 1 76.796 0.00802671 76.796 1 65.6196 0.0142145 65.62 1 S KAVPVESPVQKV_ ERK/MAPK;Proline-directed 0.0034 0.00267911 83.644 _KAVPVEpSPVQKV_ KAVPVES(1)PVQKV KAVPVES(79.28)PVQKV 7 2 680.86544 0.32954 1603400 89222 27556 0 799390 0 426290 260980 1818 1286 136 136 2287 2585 21060 12896 Mix4_TiO2_Reinj_1_6 2763 21058 12894 Mix4_TiO2_Reinj_1_5 3298 Q8TB72;Q8TB72-3;Q8TB72-2 Q8TB72 Q8TB72 >sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 OS=Homo sapiens GN=PUM2 PE=1 SV=2;>sp|Q8TB72-3|PUM2_HUMAN Isoform 3 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2;>sp|Q8TB72-2|PUM2_HUMAN Isoform 2 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2 1 7.04519 1 52.4115 0.0448291 52.412 0 0 1 7.04519 0.00485522 85.491 0 0 1 S DQKGKASPFEEDQ CK2;Proline-directed 0.05 0.00485522 85.491 _GKApSPFEEDQNR_ GKAS(1)PFEEDQNR GKAS(7.05)PFEEDQNR 4 2 729.30647 -0.4651 2709600 564790 0 0 2144800 0 0 0 1819 1286 182 182 4477;6137 5088;7005 42464 26119 Mix4_TiO2_Reinj_1_5 3756 42464 26119 Mix4_TiO2_Reinj_1_5 3756 Q8TB72;Q8TB72-3;Q8TB72-2 Q8TB72 Q8TB72 >sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 OS=Homo sapiens GN=PUM2 PE=1 SV=2;>sp|Q8TB72-3|PUM2_HUMAN Isoform 3 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2;>sp|Q8TB72-2|PUM2_HUMAN Isoform 2 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2 0.999991 50.3854 0.999739 35.8243 0.127128 35.824 0 0 0.999991 50.3854 0.000795044 80.222 0.998205 27.451 0.0455823 47.464 0.999986 48.4674 0.0425512 48.467 1 S PGSRQASPTEVVE CAMK2;CK1;CK2;Proline-directed 0.042 0.000795044 80.222 _QApSPTEVVER_ QAS(1)PTEVVER QAS(50.39)PT(-50.39)EVVER 3 2 598.27137 0.014485 2164100 482550 0 0 1185300 0 307420 188860 1820 1286 587 587 4863;4864 5529;5530 46636 28562 Mix4_TiO2_1_5 3857 46638 28564 Mix4_TiO2_Reinj_1_5 4537 Q8TB72;Q8TB72-3 Q8TB72 Q8TB72 >sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 OS=Homo sapiens GN=PUM2 PE=1 SV=2;>sp|Q8TB72-3|PUM2_HUMAN Isoform 3 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2 0.998289 29.0813 0.998289 29.0813 0.0288988 56.921 0 0 0.994772 22.9495 0.00247153 94.045 0.919529 11.2668 0.0834471 43.257 0.682501 8.55663 0.682201 12.068 1 S SATRRESLSTSSD AURORA;AURORA-1;AURORA-A;CAMK2;CK1;GSK3;PKA;PKA/AKT 0.00111111 0.00247153 94.045 _REpSLSTSSDLYK_ RES(0.998)LS(0.001)TSSDLYK RES(29.08)LS(-29.08)T(-36.61)S(-36.61)S(-43.95)DLY(-56.92)K 3 2 733.33215 -0.24416 677730 94166 0 0 495110 0 53773 34679 1821 1286 82 82 5319 6055 51626 31604 Mix4_TiO2_Reinj_1_5 6157 51626 31604 Mix4_TiO2_Reinj_1_5 6157 Q8TB72;Q8TB72-3;Q8TB72-2 Q8TB72 Q8TB72 >sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 OS=Homo sapiens GN=PUM2 PE=1 SV=2;>sp|Q8TB72-3|PUM2_HUMAN Isoform 3 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2;>sp|Q8TB72-2|PUM2_HUMAN Isoform 2 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2 1 79.1168 0.999999 62.0348 0.0214364 62.035 0 0 1 79.1168 0.00207059 79.117 1 S EVNAILSPRSESG CDK1;Proline-directed 0.0057 0.00207059 79.117 _SGQGFHGNSEVNAILpSPR_ SGQGFHGNSEVNAILS(1)PR S(-79.12)GQGFHGNS(-79.12)EVNAILS(79.12)PR 16 3 650.63369 0.11828 565600 121700 0 0 443890 0 0 0 1822 1286 178 178 6137 7005 60589 36624 Mix4_TiO2_Reinj_1_5 3953 60589 36624 Mix4_TiO2_Reinj_1_5 3953 Q8TB72;Q8TB72-3;Q8TB72-2 Q8TB72 Q8TB72 >sp|Q8TB72|PUM2_HUMAN Pumilio homolog 2 OS=Homo sapiens GN=PUM2 PE=1 SV=2;>sp|Q8TB72-3|PUM2_HUMAN Isoform 3 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2;>sp|Q8TB72-2|PUM2_HUMAN Isoform 2 of Pumilio homolog 2 OS=Homo sapiens GN=PUM2 0.990754 20.3164 0.990754 20.3164 0.00166278 88.166 2 S FNRTPGSRQASPT GSK3 0.081 0.00166278 88.166 _TPGpSRQApSPTEVVER_ T(0.009)PGS(0.991)RQAS(0.999)PT(0.001)EVVER T(-20.32)PGS(20.32)RQAS(28.58)PT(-28.58)EVVER 4 2 887.38206 0.45952 76523 0 0 0 76523 0 0 0 1823 1287 409 409 4511;5008 5124;5695 42760 26281 Mix4_TiO2_Reinj_1_3 6501 42753 26274 Mix4_InSol_Tio2_Reinj_1 6804 Q8TBE7 Q8TBE7 Q8TBE7 >sp|Q8TBE7|TMM22_HUMAN Transmembrane protein 22 OS=Homo sapiens GN=TMEM22 PE=1 SV=2 1 88.9148 1 88.8908 0.00294872 92.333 0.99999 50.1085 0.0529627 50.109 1 88.9148 0.000566801 109.76 0 0 1 106.846 0.000720925 106.85 1 127.04 7.43894E-05 127.04 1 S YQEILDSPIK___ CDK1;CDK2;Proline-directed 0.0057 7.43894E-05 127.04 _QDYQEILDpSPIK_ QDYQEILDS(1)PIK QDY(-88.91)QEILDS(88.91)PIK 9 2 764.85018 0.25339 2578500 449550 29730 0 1579800 0 385460 133920 1824 1290 498 498 1708;1709;4857 1919;1921;1923;1924;5522 46577 28529 Mix4_TiO2_Reinj_1_3 2384 15599 9440 Mix4_TiO2_Reinj_1_3 2539 Q8TCJ2 Q8TCJ2 Q8TCJ2 >sp|Q8TCJ2|STT3B_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens GN=STT3B PE=1 SV=1 0.97881 16.6456 0.958313 13.6181 1.5248E-07 133.31 0.673817 4.74651 1.85324 8.2725 0.97881 16.6456 7.34498E-12 164.46 0 0 0.890092 9.08406 0.00155214 88.916 0.854225 7.67888 0.000214707 97.984 1 S NPPVEDSSDEDDK CK2 0.117 7.34498E-12 164.46 _RENPPVEDpSSDEDDKR_ RENPPVEDS(0.979)S(0.021)DEDDKR RENPPVEDS(16.65)S(-16.65)DEDDKR 9 3 656.60413 0.051695 21420000 1.1565 6044300 84083 0 13186000 0 1205000 900100 1825 1290 499 499 1708;1709;4857 1919;1921;1923;1924;5522 15599 9440 Mix4_TiO2_Reinj_1_3 2539 15599 9440 Mix4_TiO2_Reinj_1_3 2539 Q8TCJ2 Q8TCJ2 Q8TCJ2 >sp|Q8TCJ2|STT3B_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens GN=STT3B PE=1 SV=1 0.987582 19.0051 1 3.53854 3.03887E-12 171.21 0.5 0 1.85324 8.2725 0.987582 19.0051 7.34498E-12 164.46 0 0 0.893347 9.23047 0.00155214 88.916 0.5 0 0.000214707 97.984 1 S PPVEDSSDEDDKR CK2 0.117 7.34498E-12 164.46 _ENPPVEDSpSDEDDKR_ ENPPVEDS(0.012)S(0.988)DEDDKR ENPPVEDS(-19.01)S(19.01)DEDDKR 9 2 906.352 0.33641 13928000 0.752 3904200 34969 0 8578000 0 1281500 129530 1826 1290 14 14 5718 6515 56131 34328 Mix4_InSol_TiO2_1 8658 56131 34328 Mix4_InSol_TiO2_1 8658 Q8TCJ2 Q8TCJ2 Q8TCJ2 >sp|Q8TCJ2|STT3B_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens GN=STT3B PE=1 SV=1 0.275231 1.02666 0 0 0.275231 1.02666 0.116529 47.492 0 0 1 S ESKHKSSLNSSPW AURORA;AURORA-1;GSK3 0.020748 0.116529 47.492 _SpSLNSSPWSGLMALGNSR_ S(0.217)S(0.275)LNS(0.172)S(0.168)PWS(0.168)GLMALGNSR S(-1.03)S(1.03)LNS(-2.04)S(-2.15)PWS(-2.15)GLMALGNS(-47.49)R 2 2 972.43769 -0.34737 0 0 0 0 0 0 0 0 1827 1292 3 3 517 583 4781 2881 Mix4_TiO2_Reinj_1_5 7801 4780 2880 Mix4_TiO2_Reinj_1_3 7997 Q8TCY9 Q8TCY9 Q8TCY9 >sp|Q8TCY9|URGCP_HUMAN Up-regulator of cell proliferation OS=Homo sapiens GN=URGCP PE=1 SV=2 1 82.4376 1 49.6842 0.0544609 49.684 1 82.4376 0.000918204 103.11 1 S ____MASPGIEVE Proline-directed 0.05 0.000918204 103.11 _(ac)ApSPGIEVELLGK_ AS(1)PGIEVELLGK AS(82.44)PGIEVELLGK 2 2 667.8338 -0.25544 240930 23718 0 0 217220 0 0 0 1828 1293 3 3 516 582 4771 2876 Mix4_TiO2_1_5 5205 4773 2878 Mix4_TiO2_Reinj_1_5 6039 Q8TCY9-2 Q8TCY9-2 Q8TCY9-2 >sp|Q8TCY9-2|URGCP_HUMAN Isoform 2 of Up-regulator of cell proliferation OS=Homo sapiens GN=URGCP 0.999994 52.58 0.999994 52.58 0.00450899 77.805 0 0 0.999994 52.1311 9.64145E-07 116.78 0.999738 35.8139 0.145061 41.863 0.999735 35.7691 0.0219667 63.08 1 S ____MASPGHSDL GSK3;Proline-directed 0.05 9.64145E-07 116.78 _(ac)ApSPGHSDLGEVAPEIK_ AS(1)PGHSDLGEVAPEIK AS(52.58)PGHS(-52.58)DLGEVAPEIK 2 2 864.89565 -0.74027 1440500 122350 0 0 1012400 0 180620 125090 1829 1295 582 582 2418 2741 22606 14099 Mix4_TiO2_Reinj_1_5 4608 22606 14099 Mix4_TiO2_Reinj_1_5 4608 Q8TD16-2;Q8TD16 Q8TD16-2 Q8TD16-2 >sp|Q8TD16-2|BICD2_HUMAN Isoform 2 of Protein bicaudal D homolog 2 OS=Homo sapiens GN=BICD2;>sp|Q8TD16|BICD2_HUMAN Protein bicaudal D homolog 2 OS=Homo sapiens GN=BICD2 PE=1 SV=1 1 49.982 1 49.982 0.0379779 49.982 1 S EARGRRSPILLPK PKA;Proline-directed 0.042 0.0379779 49.982 _GRRpSPILLPK_ GRRS(1)PILLPK GRRS(49.98)PILLPK 4 3 406.23571 0.051091 68354 0 0 0 68354 0 0 0 1830 1296 827 827 1653 1856;1858 15239 9196 Mix4_TiO2_Reinj_1_6 7597 15239 9196 Mix4_TiO2_Reinj_1_6 7597 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.844061 7.4949 0.333408 0 0.271442 65.199 0.220366 0 0.270434 65.253 0.844061 7.4949 2.75295E-11 125.74 0.00961989 -13.0349 0.0354649 77.845 1 S FIPMPDSPSPLSA ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.75295E-11 125.74 _ELENAEFIPM(ox)PDpSPSPLSAAFSESEKDTLPYEELQGLK_ ELENAEFIPMPDS(0.844)PS(0.15)PLS(0.005)AAFSESEKDTLPYEELQGLK ELENAEFIPMPDS(7.49)PS(-7.49)PLS(-21.93)AAFS(-35.58)ES(-48.42)EKDT(-52.76)LPY(-62.72)EELQGLK 13 3 1435.6622 -0.040713 17281000 163.77 0 0 0 17281000 0 0 0 1831 1296 829 829 1653 1856;1858 15255 9200 Mix4_TiO2_1_1 7904 15239 9196 Mix4_TiO2_Reinj_1_6 7597 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.333408 0 0.333408 0 0.271442 65.199 0.220366 0 0.270434 65.253 0.204591 -5.53431 2.75295E-11 125.74 0.0418775 -6.64682 0.0354649 77.845 1 S PMPDSPSPLSAAF Proline-directed 0.05 2.75295E-11 125.74 _ELENAEFIPMPDpSPSPLSAAFSESEKDTLPYEELQGLK_ ELENAEFIPMPDS(0.333)PS(0.333)PLS(0.283)AAFS(0.022)ES(0.022)EKDT(0.005)LPYEELQGLK ELENAEFIPMPDS(0)PS(0)PLS(-0.71)AAFS(-11.73)ES(-11.73)EKDT(-18.31)LPY(-28.54)EELQGLK 15 3 1430.3306 1.7384 0 0 0 0 0 0 0 0 0 1832 1296 836 836 1653 1856;1858 15256 9201 Mix4_TiO2_2_1 5284 15239 9196 Mix4_TiO2_Reinj_1_6 7597 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.220366 0 0.0681807 -6.1489 0.271442 65.199 0.220366 0 0.270434 65.253 0.0546174 -10.6546 2.75295E-11 125.74 0.193492 0 0.0354649 77.845 1 S PLSAAFSESEKDT CK1;CK2 0.117 2.75295E-11 125.74 _ELENAEFIPMPDpSPSPLSAAFSESEKDTLPYEELQGLK_ ELENAEFIPMPDS(0.22)PS(0.22)PLS(0.22)AAFS(0.22)ES(0.051)EKDT(0.054)LPY(0.014)EELQGLK ELENAEFIPMPDS(0)PS(0)PLS(0)AAFS(0)ES(-6.39)EKDT(-6.11)LPY(-11.97)EELQGLK 22 3 1430.3306 0.61065 0 0 0 0 0 0 0 0 0 1833 1296 838 838 1653 1856;1858 15241 9198 Mix4_TiO2_Reinj_2_1 5413 15239 9196 Mix4_TiO2_Reinj_1_6 7597 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.193492 0 0.0681807 -6.1489 0.271442 65.199 0.0505844 -6.39128 0.270434 65.253 0.0200446 -13.7681 2.75295E-11 125.74 0.193492 0 0.0354649 77.845 1 S SAAFSESEKDTLP CK2 0.117 2.75295E-11 125.74 _ELENAEFIPM(ox)PDSPSPLpSAAFSESEKDTLPYEELQGLK_ ELENAEFIPMPDS(0.01)PS(0.042)PLS(0.193)AAFS(0.193)ES(0.193)EKDT(0.193)LPY(0.175)EELQGLK ELENAEFIPMPDS(-13.03)PS(-6.65)PLS(0)AAFS(0)ES(0)EKDT(0)LPY(-0.45)EELQGLK 24 4 1076.9985 0.096099 0 0 0 0 0 0 0 0 0 1834 1296 13 13 2563 2914 24073 14936 Mix4_InSol_Tio2_Reinj_3 2590 24077 14942 Mix4_TiO2_Reinj_1_5 4638 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.228305 0 0.000229606 -33.3641 1.14946E-26 163.88 0 0 6.38433E-18 -171.879 4.30608E-47 196.9 0 0 0.0278352 -10.5558 9.00663E-19 142.51 0.228305 0 1.0083E-12 128.97 1 S YERHCDSINSDFG 4.30608E-47 196.9 _HCDpSINSDFGSESGGCGDSSPGPSASQGPR_ HCDS(0.228)INS(0.228)DFGS(0.091)ES(0.091)GGCGDS(0.091)S(0.091)PGPS(0.091)AS(0.091)QGPR HCDS(0)INS(0)DFGS(-4.02)ES(-4.02)GGCGDS(-4.02)S(-4.02)PGPS(-4.02)AS(-4.02)QGPR 4 3 1030.3926 -0.28398 0 0 0 0 0 0 0 0 0 1835 1296 16 16 2563 2914 24073 14936 Mix4_InSol_Tio2_Reinj_3 2590 24077 14942 Mix4_TiO2_Reinj_1_5 4638 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.228305 0 0.00322571 -21.8877 1.14946E-26 163.88 0 0 4.26015E-16 -153.636 4.30608E-47 196.9 0 0 0.0712006 -6.47693 9.00663E-19 142.51 0.228305 0 1.0083E-12 128.97 1 S HCDSINSDFGSES CK1;GSK3 0.081 4.30608E-47 196.9 _HCDpSINSDFGSESGGCGDSSPGPSASQGPR_ HCDS(0.228)INS(0.228)DFGS(0.091)ES(0.091)GGCGDS(0.091)S(0.091)PGPS(0.091)AS(0.091)QGPR HCDS(0)INS(0)DFGS(-4.02)ES(-4.02)GGCGDS(-4.02)S(-4.02)PGPS(-4.02)AS(-4.02)QGPR 7 3 1030.3926 -0.28398 0 0 0 0 0 0 0 0 0 1836 1296 22 22 2563 2914 24070 14933 Mix4_InSol_TiO2_3 2699 24077 14942 Mix4_TiO2_Reinj_1_5 4638 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.316357 0.321747 0.0397051 -10.9855 1.14946E-26 163.88 0 0 3.53861E-12 -114.442 4.30608E-47 196.9 0 0 0.316357 0.321747 9.00663E-19 142.51 0.0905651 -4.01554 1.0083E-12 128.97 1 S SDFGSESGGCGDS 4.30608E-47 196.9 _HCDSINSDFGSEpSGGCGDSSPGPSASQGPR_ HCDS(0.028)INS(0.071)DFGS(0.156)ES(0.316)GGCGDS(0.053)S(0.294)PGPS(0.056)AS(0.025)QGPR HCDS(-10.56)INS(-6.48)DFGS(-3.06)ES(0.32)GGCGDS(-7.74)S(-0.32)PGPS(-7.49)AS(-11.06)QGPR 13 3 1030.3926 -0.18692 0 0 0 0 0 0 0 0 0 1837 1296 28 28 2563 2914 24068 14931 Mix4_InSol_TiO2_1 4934 24077 14942 Mix4_TiO2_Reinj_1_5 4638 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.499734 0 0.498186 0.434203 1.14946E-26 163.88 0 0 0.0156592 -17.9825 4.30608E-47 196.9 0 0 0.499734 0 9.00663E-19 142.51 0.198461 -5.96622 1.0083E-12 128.97 1 S SGGCGDSSPGPSA 4.30608E-47 196.9 _HCDSINSDFGSESGGCGDpSSPGPSASQGPR_ HCDSINSDFGSESGGCGDS(0.5)S(0.5)PGPS(0.001)ASQGPR HCDS(-127.53)INS(-113.3)DFGS(-92.74)ES(-68.93)GGCGDS(0)S(0)PGPS(-29.78)AS(-49.6)QGPR 19 3 1030.3926 -0.73921 0 0 0 0 0 0 0 0 0 1838 1296 29 29 2563 2914 24071 14934 Mix4_InSol_Tio2_Reinj_1 4893 24077 14942 Mix4_TiO2_Reinj_1_5 4638 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.988756 20.2061 0.838505 7.35492 1.14946E-26 163.88 0 0 0.984063 17.9825 4.30608E-47 196.9 0 0 0.671245 6.38933 9.00663E-19 142.51 0.988756 20.2061 1.0083E-12 128.97 1 S GGCGDSSPGPSAS GSK3;Polo box;Proline-directed 0.00405 4.30608E-47 196.9 _HCDSINSDFGSESGGCGDSpSPGPSASQGPR_ HCDSINSDFGSESGGCGDS(0.009)S(0.989)PGPS(0.002)ASQGPR HCDS(-109.06)INS(-102.99)DFGS(-83.93)ES(-69.7)GGCGDS(-20.21)S(20.21)PGPS(-27.59)AS(-40.28)QGPR 20 3 1030.3926 -0.77701 7093000 0.11499 1156100 0 0 4658400 0 82144 1196400 1839 1296 331 331 4999;5765 5685;6569 48258 29481 Mix4_InSol_Tio2_Reinj_1 6044 56730 34614 Mix4_TiO2_1_5 5362 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.456202 0 0.390478 -1.36602 1.37711E-16 190.81 0.383567 -1.56119 0.00254408 82.191 0.398028 -1.35558 3.97906E-13 175.31 0 0 0.362441 -2.42775 4.18384E-16 181.82 0.456202 0 6.41205E-12 165.91 1 S PTKRPRSSTVTEA CAMK2;PKA 0.003024 1.37711E-16 190.81 _RPRpSSTVTEAPIAVVTSR_ RPRS(0.456)S(0.456)T(0.084)VT(0.004)EAPIAVVTSR RPRS(0)S(0)T(-7.37)VT(-20.74)EAPIAVVT(-36.79)S(-36.79)R 4 3 669.68428 0.34282 0 0 0 0 0 0 0 0 0 1840 1296 332 332 4999;5765 5685;6569 56717 34596 Mix4_InSol_TiO2_1 6702 56730 34614 Mix4_TiO2_1_5 5362 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.633888 2.42775 0.620258 2.18398 1.37711E-16 190.81 0.549491 1.56119 0.00254408 82.191 0.595438 2.41982 3.97906E-13 175.31 0 0 0.633888 2.42775 4.18384E-16 181.82 0.625677 2.23835 6.41205E-12 165.91 1 S TKRPRSSTVTEAP PKA 0.042 1.37711E-16 190.81 _SpSTVTEAPIAVVTSR_ S(0.362)S(0.634)T(0.004)VTEAPIAVVTSR S(-2.43)S(2.43)T(-22.37)VT(-78.83)EAPIAVVT(-181.82)S(-181.82)R 2 2 799.39528 -0.21434 5754700 330.37 1233500 31809 0 3500000 0 533350 455960 1841 1296 737 737 5529 6297 54083 33118 Mix4_TiO2_Reinj_1_5 7342 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.399707 0.313645 0.327957 0 0.0679074 77.91 0.0896598 -2.97299 0.618044 61.442 0.399707 0.313645 4.02343E-06 112.15 0 0 0 0 0 0 1 S KTIRSNSSGLSIG CAMK2;GSK3 0.042 4.02343E-06 112.15 _SNpSSGLSIGTVFQSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR_ S(0.372)NS(0.4)S(0.183)GLS(0.017)IGT(0.011)VFQS(0.004)S(0.003)S(0.004)PGGGGGGGGGEEEDS(0.005)QQES(0.001)ETPDPSGGFR S(-0.31)NS(0.31)S(-3.38)GLS(-13.74)IGT(-15.75)VFQS(-19.55)S(-20.64)S(-20.34)PGGGGGGGGGEEEDS(-19.36)QQES(-25.89)ET(-33.74)PDPS(-38.56)GGFR 3 4 1088.9547 0.29114 0 0 0 0 0 0 0 0 0 1842 1296 738 738 5529 6297 54082 33116 Mix4_TiO2_Reinj_1_5 7337 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.336665 0 0.327957 0 0.0679074 77.91 0.0896598 -2.97299 0.618044 61.442 0.336665 0 4.02343E-06 112.15 0 0 0 0 0 0 1 S TIRSNSSGLSIGT CK1 0.081 4.02343E-06 112.15 _SNpSSGLSIGTVFQSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR_ S(0.301)NS(0.337)S(0.337)GLS(0.025)IGT(0.001)VFQSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR S(-0.48)NS(0)S(0)GLS(-11.32)IGT(-27.44)VFQS(-46.21)S(-46.21)S(-50.45)PGGGGGGGGGEEEDS(-64.73)QQES(-68.25)ET(-73.78)PDPS(-80.78)GGFR 4 3 1451.6039 -0.52342 0 0 0 0 0 0 0 0 0 1843 1296 741 741 5529 6297 54077 33110 Mix4_TiO2_1_5 6588 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.330786 3.15262 0.330786 3.15262 0.0679074 77.91 0.0896598 -2.97299 0.618044 61.442 0.0264669 -10.8591 4.02343E-06 112.15 0 0 0 0 0 0 1 S SNSSGLSIGTVFQ CK1 0.081 4.02343E-06 112.15 _SNSSGLpSIGTVFQSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR_ S(0.124)NS(0.131)S(0.131)GLS(0.331)IGT(0.16)VFQS(0.039)S(0.039)S(0.039)PGGGGGGGGGEEEDS(0.004)QQES(0.002)ETPDPSGGFR S(-4.27)NS(-4.03)S(-4.03)GLS(3.15)IGT(-3.15)VFQS(-9.26)S(-9.26)S(-9.26)PGGGGGGGGGEEEDS(-19.44)QQES(-23.34)ET(-29.52)PDPS(-33.6)GGFR 7 4 1088.9547 0.70633 0 0 0 0 0 0 0 0 0 1844 1296 748 748 5529 6297 54081 33114 Mix4_TiO2_Reinj_1_5 7222 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.330237 0 0.0392051 -9.26205 0.0679074 77.91 0.110016 -2.0844 0.618044 61.442 0.330237 0 4.02343E-06 112.15 0 0 0 0 0 0 1 S IGTVFQSSSPGGG CK1 0.143 4.02343E-06 112.15 _SNSSGLSIGTVFQpSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR_ SNSSGLSIGT(0.001)VFQS(0.33)S(0.33)S(0.33)PGGGGGGGGGEEEDS(0.004)QQES(0.005)ETPDPSGGFR S(-46.55)NS(-46.2)S(-46.2)GLS(-42.44)IGT(-28.1)VFQS(0)S(0)S(0)PGGGGGGGGGEEEDS(-19.5)QQES(-18.52)ET(-29.45)PDPS(-44.7)GGFR 14 3 1451.6039 -0.1954 0 0 0 0 0 0 0 0 0 1845 1296 749 749 5529 6297 54081 33114 Mix4_TiO2_Reinj_1_5 7222 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.330237 0 0.0392051 -9.26205 0.0679074 77.91 0.110016 -2.0844 0.618044 61.442 0.330237 0 4.02343E-06 112.15 0 0 0 0 0 0 1 S GTVFQSSSPGGGG 4.02343E-06 112.15 _SNSSGLSIGTVFQpSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR_ SNSSGLSIGT(0.001)VFQS(0.33)S(0.33)S(0.33)PGGGGGGGGGEEEDS(0.004)QQES(0.005)ETPDPSGGFR S(-46.55)NS(-46.2)S(-46.2)GLS(-42.44)IGT(-28.1)VFQS(0)S(0)S(0)PGGGGGGGGGEEEDS(-19.5)QQES(-18.52)ET(-29.45)PDPS(-44.7)GGFR 15 3 1451.6039 -0.1954 0 0 0 0 0 0 0 0 0 1846 1296 750 750 5529 6297 54081 33114 Mix4_TiO2_Reinj_1_5 7222 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.330237 0 0.0392051 -9.26205 0.0679074 77.91 0.110016 -2.0844 0.618044 61.442 0.330237 0 4.02343E-06 112.15 0 0 0 0 0 0 1 S TVFQSSSPGGGGG Polo box;Proline-directed 0.00405 4.02343E-06 112.15 _SNSSGLSIGTVFQpSSSPGGGGGGGGGEEEDSQQESETPDPSGGFR_ SNSSGLSIGT(0.001)VFQS(0.33)S(0.33)S(0.33)PGGGGGGGGGEEEDS(0.004)QQES(0.005)ETPDPSGGFR S(-46.55)NS(-46.2)S(-46.2)GLS(-42.44)IGT(-28.1)VFQS(0)S(0)S(0)PGGGGGGGGGEEEDS(-19.5)QQES(-18.52)ET(-29.45)PDPS(-44.7)GGFR 16 3 1451.6039 -0.1954 0 0 0 0 0 0 0 0 0 1847 1296 765 765 5529 6297 54079 33112 Mix4_TiO2_2_2 6303 54081 33114 Mix4_TiO2_Reinj_1_5 7222 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.177786 2.0844 0.0037623 -19.4409 0.0679074 77.91 0.177786 2.0844 0.618044 61.442 0.00462829 -19.3632 4.02343E-06 112.15 0 0 0 0 0 0 1 S GGEEEDSQQESET CK2;GSK3 0.081 4.02343E-06 112.15 _SNSSGLSIGTVFQSSSPGGGGGGGGGEEEDpSQQESETPDPSGGFR_ S(0.084)NS(0.09)S(0.09)GLS(0.09)IGT(0.11)VFQS(0.11)S(0.11)S(0.11)PGGGGGGGGGEEEDS(0.178)QQES(0.02)ET(0.008)PDPS(0.001)GGFR S(-3.26)NS(-2.97)S(-2.97)GLS(-2.97)IGT(-2.08)VFQS(-2.08)S(-2.08)S(-2.08)PGGGGGGGGGEEEDS(2.08)QQES(-9.49)ET(-13.55)PDPS(-21.02)GGFR 31 3 1451.6039 0.020581 0 0 0 0 0 0 0 0 0 1848 1296 357 357 5797;6214 6603;7098 61577 37328 Mix4_InSol_TiO2_1 7141 61577 37328 Mix4_InSol_TiO2_1 7141 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.5 0 0.414012 -1.50875 0.150398 33.896 0.42384 -1.33341 0.21678 28.396 0.5 0 0.000255897 89.991 0 0 1 S VWGGGKSTPQKLD 0.000255897 89.991 _TSEVYVWGGGKpSTPQKLDVIK_ TSEVYVWGGGKS(0.5)T(0.5)PQKLDVIK T(-89.99)S(-89.99)EVY(-82.82)VWGGGKS(0)T(0)PQKLDVIK 12 3 791.40144 0.46433 89325 0 0 0 0 0 89325 0 1849 1296 2 2 5831 6649 57488 34991 Mix4_TiO2_Reinj_1_5 5974 57488 34991 Mix4_TiO2_Reinj_1_5 5974 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.999951 43.0769 0.882121 8.74093 0.99449 8.7409 0.999951 43.0769 0.133404 43.077 1 S _____MSVLGEYE 0.133404 43.077 _(ac)pSVLGEYER_ S(1)VLGEYER S(43.08)VLGEY(-43.08)ER 1 2 537.7288 -0.075581 489910 63604 0 0 426310 0 0 0 1850 1296 868 868 6342;6343 7251;7253 63901 39147 Mix4_InSol_TiO2_1 4244 63928 39214 Mix4_TiO2_Reinj_1_5 3850 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.975491 15.999 0.974959 15.9033 8.78465E-22 172.66 0.973239 15.6072 0.000435396 91.462 0.910092 10.0529 1.53464E-22 175.36 0.835672 7.10604 0.709792 27.149 0.975491 15.999 1.17727E-15 145.63 0.965558 14.4776 2.53092E-21 166.45 1 S KPQVEASSPRLNP 1.53464E-22 175.36 _VASEAPLEHKPQVEApSSPR_ VASEAPLEHKPQVEAS(0.975)S(0.025)PR VAS(-109.71)EAPLEHKPQVEAS(16)S(-16)PR 16 3 704.67556 -0.39543 83960000 254.01 16130000 726680 0 51960000 149040 8897200 6097000 1851 1296 869 869 6342;6343 7251;7253 63928 39214 Mix4_TiO2_Reinj_1_5 3850 63928 39214 Mix4_TiO2_Reinj_1_5 3850 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.999682 34.9801 0.999477 32.8103 8.78465E-22 172.66 0.977629 16.4049 0.000435396 91.462 0.999682 34.9801 1.53464E-22 175.36 0.765322 5.1889 0.709792 27.149 0.976412 16.1694 1.17727E-15 145.63 0.996875 25.0374 2.53092E-21 166.45 1 S PQVEASSPRLNPA CDK1;Polo box;Proline-directed 0.00405 1.53464E-22 175.36 _VASEAPLEHKPQVEASpSPR_ VASEAPLEHKPQVEASS(1)PR VAS(-168.38)EAPLEHKPQVEAS(-34.98)S(34.98)PR 17 2 1056.5097 -0.50394 32283000 97.668 3206600 95406 0 19629000 9066.6 2008500 7333500 1852 1297 9 9 501 567 4652 2818 Mix4_TiO2_Reinj_1_3 6556 4652 2818 Mix4_TiO2_Reinj_1_3 6556 Q8TDB6;Q8TDB6-2 Q8TDB6 Q8TDB6 >sp|Q8TDB6|DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L OS=Homo sapiens GN=DTX3L PE=1 SV=1;>sp|Q8TDB6-2|DTX3L_HUMAN Isoform 2 of E3 ubiquitin-protein ligase DTX3L OS=Homo sapiens GN=DTX3L 0.999894 39.7478 0.871462 8.31217 0.792079 8.3122 0.999894 39.7478 0.11124 39.748 1 S SHLRPPSPLLVRV CAMK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.11124 39.748 _(ac)ASHLRPPpSPLLVR_ ASHLRPPS(1)PLLVR AS(-39.75)HLRPPS(39.75)PLLVR 8 3 522.2835 -0.30045 476270 103950 0 0 372320 0 0 0 1853 1298 782 782 2715 3094 25671 15856 Mix4_TiO2_Reinj_1_5 2336 25671 15856 Mix4_TiO2_Reinj_1_5 2336 Q8TDD1 Q8TDD1 Q8TDD1 >sp|Q8TDD1|DDX54_HUMAN ATP-dependent RNA helicase DDX54 OS=Homo sapiens GN=DDX54 PE=1 SV=2 0.999987 48.7779 0.999838 37.8994 0.166386 37.899 0.999987 48.7779 0.0721166 48.778 1 S KIDDRDSDEEGAS CK2;PKA 0.042 0.0721166 48.778 _IDDRDpSDEEGASDR_ IDDRDS(1)DEEGASDR IDDRDS(48.78)DEEGAS(-48.78)DR 6 2 830.31013 0.23403 68598 28166 0 0 40432 0 0 0 1854 1299 1857 1857 4113 4683 38977 23909 Mix4_TiO2_Reinj_1_1 7654 38977 23909 Mix4_TiO2_Reinj_1_1 7654 Q8TDJ6 Q8TDJ6 Q8TDJ6 >sp|Q8TDJ6|DMXL2_HUMAN DmX-like protein 2 OS=Homo sapiens GN=DMXL2 PE=1 SV=2 0.999592 33.9066 0 0 0.999592 33.9066 0.000110337 98.716 1 S IRRNLASPEGTLA Proline-directed 0.05 0.000110337 98.716 _NLApSPEGTLATLGLK_ NLAS(1)PEGTLATLGLK NLAS(33.91)PEGT(-33.91)LAT(-58.05)LGLK 4 2 782.90275 0.3905 91647 0 0 0 91647 0 0 0 1855 1300 168 168 2182 2470 20040 12341 Mix4_TiO2_Reinj_1_3 5338 20040 12341 Mix4_TiO2_Reinj_1_3 5338 Q8TDN4 Q8TDN4 Q8TDN4 >sp|Q8TDN4|CABL1_HUMAN CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens GN=CABLES1 PE=1 SV=2 1 61.6233 1 57.0983 0.0164837 57.098 1 61.6233 0.00656069 61.623 0 0 0 0 1 S VARGFASPLGAGR Proline-directed 0.05 0.00656069 61.623 _GFApSPLGAGR_ GFAS(1)PLGAGR GFAS(61.62)PLGAGR 4 2 506.73422 -0.14596 132550 27193 0 0 105350 0 0 0 1856 1300 291 291 5715 6512 56117 34324 Mix4_TiO2_1_3 7202 56117 34324 Mix4_TiO2_1_3 7202 Q8TDN4;Q8TDN4-2 Q8TDN4 Q8TDN4 >sp|Q8TDN4|CABL1_HUMAN CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens GN=CABLES1 PE=1 SV=2;>sp|Q8TDN4-2|CABL1_HUMAN Isoform 2 of CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens GN=CABLES1 0.56773 1.18503 0.56773 1.18503 0.0291216 59.654 0 0 1 S LISQRSSLETLED AURORA;AURORA-1;CK1;PKA 0.020748 0.0291216 59.654 _SpSLETLEDIEENAPLR_ S(0.432)S(0.568)LETLEDIEENAPLR S(-1.19)S(1.19)LET(-36.9)LEDIEENAPLR 2 2 948.43534 0.56295 49228 49228 0 0 0 0 0 0 1857 1302 650 650 547 623 5170 3158 Mix4_TiO2_Reinj_1_1 2091 5170 3158 Mix4_TiO2_Reinj_1_1 2091 Q8TDY2 Q8TDY2 Q8TDY2 >sp|Q8TDY2|RBCC1_HUMAN RB1-inducible coiled-coil protein 1 OS=Homo sapiens GN=RB1CC1 PE=1 SV=3 0.560357 1.25249 0 0 0.560357 1.25249 0.0807387 50.191 0 0 1 S SQTSPQSASSPRM CK1 0.081 0.0807387 50.191 _ASVSQTSPQpSASSPR_ ASVS(0.007)QT(0.001)S(0.42)PQS(0.56)AS(0.012)SPR AS(-35.26)VS(-19.29)QT(-26.05)S(-1.25)PQS(1.25)AS(-16.87)S(-48.85)PR 10 2 785.34887 0.64247 24168 0 0 0 24168 0 0 0 1858 1303 872 872 1824 2059 16731 10060 Mix4_TiO2_Reinj_1_5 9144 16731 10060 Mix4_TiO2_Reinj_1_5 9144 Q8TDZ2;Q8TDZ2-2;Q8TDZ2-3 Q8TDZ2 Q8TDZ2 >sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2;>sp|Q8TDZ2-2|MICA1_HUMAN Isoform 2 of NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1;>sp 0.666667 0 0.666667 0 1.06213E-07 108.41 2 S EKEEKESPFSSEE GSK3;Proline-directed 0.05 1.06213E-07 108.41 _EpSPFpSSEEEEEDVPLDSDVEQALQTFAK_ ES(0.667)PFS(0.667)S(0.667)EEEEEDVPLDSDVEQALQTFAK ES(0)PFS(0)S(0)EEEEEDVPLDS(-99.9)DVEQALQT(-108.41)FAK 2 3 1105.7845 0.078006 120320 0 0 0 120320 0 0 0 1859 1303 875 875 1824 2059 16731 10060 Mix4_TiO2_Reinj_1_5 9144 16731 10060 Mix4_TiO2_Reinj_1_5 9144 Q8TDZ2;Q8TDZ2-2;Q8TDZ2-3 Q8TDZ2 Q8TDZ2 >sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2;>sp|Q8TDZ2-2|MICA1_HUMAN Isoform 2 of NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1;>sp 0.666667 0 0.666667 0 1.06213E-07 108.41 2 S EKESPFSSEEEEE CK1;CK2 0.081 1.06213E-07 108.41 _EpSPFpSSEEEEEDVPLDSDVEQALQTFAK_ ES(0.667)PFS(0.667)S(0.667)EEEEEDVPLDSDVEQALQTFAK ES(0)PFS(0)S(0)EEEEEDVPLDS(-99.9)DVEQALQT(-108.41)FAK 5 3 1105.7845 0.078006 120320 0 0 0 120320 0 0 0 1860 1303 876 876 1824 2059 16731 10060 Mix4_TiO2_Reinj_1_5 9144 16731 10060 Mix4_TiO2_Reinj_1_5 9144 Q8TDZ2;Q8TDZ2-2;Q8TDZ2-3 Q8TDZ2 Q8TDZ2 >sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2;>sp|Q8TDZ2-2|MICA1_HUMAN Isoform 2 of NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1;>sp 0.666667 0 0.666667 0 1.06213E-07 108.41 2 S KESPFSSEEEEED CK1;CK2 0.117 1.06213E-07 108.41 _EpSPFpSSEEEEEDVPLDSDVEQALQTFAK_ ES(0.667)PFS(0.667)S(0.667)EEEEEDVPLDSDVEQALQTFAK ES(0)PFS(0)S(0)EEEEEDVPLDS(-99.9)DVEQALQT(-108.41)FAK 6 3 1105.7845 0.078006 120320 0 0 0 120320 0 0 0 1861 1307 262 262 2459 2789 23097 14423 Mix4_InSol_Tio2_Reinj_1 3430 23096 14422 Mix4_InSol_TiO2_1 3458 Q8TER5;Q8TER5-3;Q8TER5-4 Q8TER5 Q8TER5 >sp|Q8TER5|SOLO_HUMAN Protein SOLO OS=Homo sapiens GN=SOLO PE=1 SV=3;>sp|Q8TER5-3|SOLO_HUMAN Isoform 3 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-4|SOLO_HUMAN Isoform 4 of Protein SOLO OS=Homo sapiens GN=SOLO 1 65.9583 0.999279 32.709 0.0001964 101.24 0 0 0.997595 26.2329 0.00321383 80.751 0.999642 34.4663 7.46962E-09 144.62 1 65.9583 1.18001E-05 117.22 1 S PTDAEGSPGLSRV GSK3;Proline-directed 0.05 7.46962E-09 144.62 _GSPTDAEGpSPGLSR_ GSPTDAEGS(1)PGLSR GS(-100.45)PT(-67.06)DAEGS(65.96)PGLS(-65.96)R 9 2 705.79848 -0.05718 718110 4.4046 56113 0 0 269920 0 198850 193230 1862 1307 1474 1474 4583 5204 43346 26571 Mix4_InSol_TiO2_1 6805 43346 26571 Mix4_InSol_TiO2_1 6805 Q8TER5;Q8TER5-2 Q8TER5 Q8TER5 >sp|Q8TER5|SOLO_HUMAN Protein SOLO OS=Homo sapiens GN=SOLO PE=1 SV=3;>sp|Q8TER5-2|SOLO_HUMAN Isoform 2 of Protein SOLO OS=Homo sapiens GN=SOLO 1 68.1222 0 0 1 68.1222 2.12689E-10 118.89 0 0 1 S DSSGDVSPGPRNS CK1;Proline-directed 0.05 2.12689E-10 118.89 _QISLAPETLDSSGDVpSPGPR_ QISLAPETLDSSGDVS(1)PGPR QIS(-108.87)LAPET(-102.14)LDS(-79.51)S(-68.12)GDVS(68.12)PGPR 16 2 1053.4912 0.79262 31589 0 0 0 0 0 31589 0 1863 1307 984 984 5585 6365 54621 33438 Mix4_TiO2_Reinj_1_1 7581 54621 33438 Mix4_TiO2_Reinj_1_1 7581 Q8TER5;Q8TER5-3;Q8TER5-4;Q8TER5-2 Q8TER5 Q8TER5 >sp|Q8TER5|SOLO_HUMAN Protein SOLO OS=Homo sapiens GN=SOLO PE=1 SV=3;>sp|Q8TER5-3|SOLO_HUMAN Isoform 3 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-4|SOLO_HUMAN Isoform 4 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-2|SOLO_HUMAN Isoform 2 of Pr 0.496702 0 0.457303 -0.690362 0.126937 46.065 0.496702 0 0.00514455 76.406 1 S AQWGPRSPSPSLS ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.00514455 76.406 _pSPSPSLSSLLLPSSPGPR_ S(0.497)PS(0.497)PS(0.007)LSSLLLPSSPGPR S(0)PS(0)PS(-18.78)LS(-48.71)S(-47.78)LLLPS(-76.41)S(-76.41)PGPR 1 2 929.96915 0.184 0 0 0 0 0 0 0 0 1864 1307 986 986 5585 6365 54620 33436 Mix4_TiO2_1_5 7221 54621 33438 Mix4_TiO2_Reinj_1_1 7581 Q8TER5;Q8TER5-3;Q8TER5-4;Q8TER5-2 Q8TER5 Q8TER5 >sp|Q8TER5|SOLO_HUMAN Protein SOLO OS=Homo sapiens GN=SOLO PE=1 SV=3;>sp|Q8TER5-3|SOLO_HUMAN Isoform 3 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-4|SOLO_HUMAN Isoform 4 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-2|SOLO_HUMAN Isoform 2 of Pr 0.536094 0.690362 0.536094 0.690362 0.126937 46.065 0.496702 0 0.00514455 76.406 1 S WGPRSPSPSLSSL CAMK2;GSK3;PKA/AKT;Proline-directed 0.00111111 0.00514455 76.406 _SPpSPSLSSLLLPSSPGPR_ S(0.457)PS(0.536)PS(0.006)LSSLLLPSSPGPR S(-0.69)PS(0.69)PS(-19.28)LS(-36.5)S(-36.03)LLLPS(-46.07)S(-46.07)PGPR 3 2 929.96915 0.15541 40150 40150 0 0 0 0 0 0 1865 1307 997 997 5585 6365 54619 33434 Mix4_TiO2_1_1 6723 54621 33438 Mix4_TiO2_Reinj_1_1 7581 Q8TER5;Q8TER5-3;Q8TER5-4;Q8TER5-2 Q8TER5 Q8TER5 >sp|Q8TER5|SOLO_HUMAN Protein SOLO OS=Homo sapiens GN=SOLO PE=1 SV=3;>sp|Q8TER5-3|SOLO_HUMAN Isoform 3 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-4|SOLO_HUMAN Isoform 4 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-2|SOLO_HUMAN Isoform 2 of Pr 0.499052 4.2506 0.499052 4.2506 0.126937 46.065 1.1364E-08 -76.4057 0.00514455 76.406 1 S SLLLPSSPGPRPA ERK/MAPK;NEK6;Polo box;Proline-directed;WW GroupIV 0.0023175 0.00514455 76.406 _SPSPSLSSLLLPSpSPGPR_ S(0.113)PS(0.131)PS(0.023)LS(0.023)S(0.023)LLLPS(0.188)S(0.499)PGPR S(-6.45)PS(-5.81)PS(-13.35)LS(-13.35)S(-13.35)LLLPS(-4.25)S(4.25)PGPR 14 2 929.96915 0.32352 0 0 0 0 0 0 0 0 1866 1309 143 143 1209 1361 11363 6967 Mix4_TiO2_Reinj_1_5 5183 11358 6962 Mix4_TiO2_1_3 4461 Q8TF76;Q8TF76-2 Q8TF76 Q8TF76 >sp|Q8TF76|HASP_HUMAN Serine/threonine-protein kinase haspin OS=Homo sapiens GN=GSG2 PE=1 SV=3;>sp|Q8TF76-2|HASP_HUMAN Isoform 2 of Serine/threonine-protein kinase haspin OS=Homo sapiens GN=GSG2 0.693074 3.53745 0.404603 -1.67775 7.67702E-13 152.73 0 0 0.693074 3.53745 4.07799E-09 131.99 0.0114026 -19.3799 0.00128116 88.881 0.000364218 -34.3848 1.43674E-12 149.31 1 S PFPSRDSGRLSPD CK1;F box bTrCP;GSK3;PKA 0.000624338 7.67702E-13 152.73 _DpSGRLSPDLSVCGQPR_ DS(0.693)GRLS(0.307)PDLSVCGQPR DS(3.54)GRLS(-3.54)PDLS(-75.56)VCGQPR 2 3 608.60838 0.068607 832510 0 0 0 832510 0 0 0 1867 1309 147 147 1209 1361 11364 6968 Mix4_TiO2_Reinj_1_5 5202 11358 6962 Mix4_TiO2_1_3 4461 Q8TF76;Q8TF76-2 Q8TF76 Q8TF76 >sp|Q8TF76|HASP_HUMAN Serine/threonine-protein kinase haspin OS=Homo sapiens GN=GSG2 PE=1 SV=3;>sp|Q8TF76-2|HASP_HUMAN Isoform 2 of Serine/threonine-protein kinase haspin OS=Homo sapiens GN=GSG2 0.999985 48.8764 0.999531 33.314 7.67702E-13 152.73 0 0 0.999985 48.8764 4.07799E-09 131.99 0.988535 19.3799 0.00128116 88.881 0.999636 34.3848 1.43674E-12 149.31 1 S RDSGRLSPDLSVC CK1;F box bTrCP;GSK3;PKA;Proline-directed 0.000624338 7.67702E-13 152.73 _DSGRLpSPDLSVCGQPR_ DSGRLS(1)PDLSVCGQPR DS(-48.88)GRLS(48.88)PDLS(-56.63)VCGQPR 6 2 912.40893 -0.12155 2317100 450980 0 0 1287900 0 308650 269520 1868 1309 60 60 1984 2244 18073 10792 Mix4_TiO2_1_3 6297 18073 10792 Mix4_TiO2_1_3 6297 Q8TF76;Q8TF76-2 Q8TF76 Q8TF76 >sp|Q8TF76|HASP_HUMAN Serine/threonine-protein kinase haspin OS=Homo sapiens GN=GSG2 PE=1 SV=3;>sp|Q8TF76-2|HASP_HUMAN Isoform 2 of Serine/threonine-protein kinase haspin OS=Homo sapiens GN=GSG2 0.753499 4.85569 0.753499 4.85569 3.47747E-07 99.884 0 0 1 S IGDPSQSDDPDDP 3.47747E-07 99.884 _FFNSSGSSDASIGDPSQpSDDPDDPDDPDFPGSPVR_ FFNSSGSSDASIGDPS(0.246)QS(0.753)DDPDDPDDPDFPGSPVR FFNS(-40.76)S(-40.76)GS(-47.54)S(-47.54)DAS(-46.24)IGDPS(-4.86)QS(4.86)DDPDDPDDPDFPGS(-56.81)PVR 18 3 1236.1586 0.42045 258800 258800 0 0 0 0 0 0 1869 1310 7 7 552 631 5220 3182 Mix4_InSol_Tio2_Reinj_1 3765 5224 3186 Mix4_TiO2_Reinj_1_5 3584 Q8WTW3 Q8WTW3 Q8WTW3 >sp|Q8WTW3|COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens GN=COG1 PE=1 SV=1 0.999856 38.6346 0.997474 25.9706 0.0315663 54.102 0 0 0.997093 27.7185 0.00921636 64.347 0.991197 20.533 0.0642353 44.414 0.999856 38.6346 0.040527 51.444 1 S MATAATSPALKRL CK1;Proline-directed 0.05 0.00921636 64.347 _(ac)ATAATpSPALKR_ ATAATS(1)PALKR AT(-51.44)AAT(-38.63)S(38.63)PALKR 6 2 604.80538 0.5821 437580 72225 0 0 250450 0 66205 48698 1870 1310 455 455 1667 1873 15320 9246 Mix4_TiO2_Reinj_1_5 8757 15319 9244 Mix4_TiO2_Reinj_1_3 8978 Q8WTW3 Q8WTW3 Q8WTW3 >sp|Q8WTW3|COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens GN=COG1 PE=1 SV=1 0.282407 0 0.0387419 -12.476 1.41405E-23 157.8 0.282407 0 6.23324E-66 270.69 1 S LQELESSTSNSPS GSK3;NEK6 0.076 6.23324E-66 270.69 _ELLVSALQELESpSTSNSPSNK_ ELLVSALQELESS(0.282)T(0.282)S(0.282)NS(0.152)PSNK ELLVS(-73.49)ALQELES(-28.27)S(0)T(0)S(0)NS(-2.68)PS(-37.66)NK 13 3 771.7001 -0.062388 0 0 0 0 0 0 0 0 0 1871 1310 457 457 1667 1873 15320 9246 Mix4_TiO2_Reinj_1_5 8757 15319 9244 Mix4_TiO2_Reinj_1_3 8978 Q8WTW3 Q8WTW3 Q8WTW3 >sp|Q8WTW3|COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens GN=COG1 PE=1 SV=1 0.282407 0 0.172109 -5.99979 1.41405E-23 157.8 0.282407 0 6.23324E-66 270.69 1 S ELESSTSNSPSNK CK1;GSK3 0.081 6.23324E-66 270.69 _ELLVSALQELESpSTSNSPSNK_ ELLVSALQELESS(0.282)T(0.282)S(0.282)NS(0.152)PSNK ELLVS(-73.49)ALQELES(-28.27)S(0)T(0)S(0)NS(-2.68)PS(-37.66)NK 15 3 771.7001 -0.062388 0 0 0 0 0 0 0 0 0 1872 1310 459 459 1667 1873 15319 9244 Mix4_TiO2_Reinj_1_3 8978 15319 9244 Mix4_TiO2_Reinj_1_3 8978 Q8WTW3 Q8WTW3 Q8WTW3 >sp|Q8WTW3|COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens GN=COG1 PE=1 SV=1 0.995228 23.2981 0.695018 6.21857 1.41405E-23 157.8 0.995228 23.2981 6.23324E-66 270.69 1 S ESSTSNSPSNKHI CK1;Proline-directed 0.05 6.23324E-66 270.69 _ELLVSALQELESSTSNpSPSNK_ ELLVSALQELESSTSNS(0.995)PS(0.005)NK ELLVS(-205.18)ALQELES(-106.11)S(-72.72)T(-48.26)S(-39.99)NS(23.3)PS(-23.3)NK 17 2 1157.0465 -0.22277 938650 0.60898 158350 0 0 780290 0 0 0 1873 1312 50 50 3040 3458 29002 18043 Mix4_TiO2_Reinj_1_5 7573 29002 18043 Mix4_TiO2_Reinj_1_5 7573 Q8WUM0 Q8WUM0 Q8WUM0 >sp|Q8WUM0|NU133_HUMAN Nuclear pore complex protein Nup133 OS=Homo sapiens GN=NUP133 PE=1 SV=2 1 87.0395 0 0 1 87.0395 0.000429569 87.04 1 S SSPVLFSPVGRRS Proline-directed 0.05 0.000429569 87.04 _KGLPLGSAVSSPVLFpSPVGR_ KGLPLGSAVSSPVLFS(1)PVGR KGLPLGS(-87.04)AVS(-87.04)S(-87.04)PVLFS(87.04)PVGR 16 3 683.36952 -0.18471 102270 0 0 0 102270 0 0 0 1874 1314 277 277 3139 3564 29820 18565 Mix4_TiO2_Reinj_1_3 1580 29820 18565 Mix4_TiO2_Reinj_1_3 1580 Q8WUM9 Q8WUM9 Q8WUM9 >sp|Q8WUM9|S20A1_HUMAN Sodium-dependent phosphate transporter 1 OS=Homo sapiens GN=SLC20A1 PE=1 SV=1 0.999988 49.0729 0.999988 49.0729 0.032952 49.073 1 S LMEKKNSLKEDHE AURORA;AURORA-1;AURORA-A;CHK1;CK2 0.006142092 0.032952 49.073 _KNpSLKEDHEETK_ KNS(1)LKEDHEETK KNS(49.07)LKEDHEET(-49.07)K 3 2 769.34833 0.098596 204190 0 0 0 204190 0 0 0 1875 1316 126 126 2488 2827 23425 14572 Mix4_TiO2_Reinj_1_4 4886 23425 14572 Mix4_TiO2_Reinj_1_4 4886 Q8WUZ0-2;Q8WUZ0 Q8WUZ0-2 Q8WUZ0-2 >sp|Q8WUZ0-2|BCL7C_HUMAN Isoform 2 of B-cell CLL/lymphoma 7 protein family member C OS=Homo sapiens GN=BCL7C;>sp|Q8WUZ0|BCL7C_HUMAN B-cell CLL/lymphoma 7 protein family member C OS=Homo sapiens GN=BCL7C PE=1 SV=3 0.995371 23.349 0 0 0.995371 23.349 2.24496E-08 115.61 1 S QPSRPVSPAGPPE CAMK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.24496E-08 115.61 _GTEPSPGGTPQPSRPVpSPAGPPEGVPEEAQPPR_ GTEPSPGGTPQPS(0.005)RPVS(0.995)PAGPPEGVPEEAQPPR GT(-47.56)EPS(-63.49)PGGT(-51.12)PQPS(-23.35)RPVS(23.35)PAGPPEGVPEEAQPPR 17 3 1113.8596 -0.075825 332830 0 0 0 332830 0 0 0 1876 1317 899 899 6393 7314 64596 39622 Mix4_TiO2_Reinj_1_5 8400 64596 39622 Mix4_TiO2_Reinj_1_5 8400 Q8WVB6-2;Q8WVB6;Q8WVB6-3 Q8WVB6-2 Q8WVB6-2 >sp|Q8WVB6-2|CTF18_HUMAN Isoform 2 of Chromosome transmission fidelity protein 18 homolog OS=Homo sapiens GN=CHTF18;>sp|Q8WVB6|CTF18_HUMAN Chromosome transmission fidelity protein 18 homolog OS=Homo sapiens GN=CHTF18 PE=1 SV=1;>sp|Q8WVB6-3|CTF18_HUMAN Isof 1 67.2887 1 67.7288 0.00025097 90.411 1 67.2887 4.29163E-26 173.17 1 S SPQVDGSPPGLEG Proline-directed 0.05 4.29163E-26 173.17 _VENSPQVDGpSPPGLEGLLGGIGEK_ VENSPQVDGS(1)PPGLEGLLGGIGEK VENS(-67.29)PQVDGS(67.29)PPGLEGLLGGIGEK 10 3 810.39138 -0.01748 538710 189030 0 0 349680 0 0 0 1877 1318 297 297 6507 7445 65748 40312 Mix4_InSol_Tio2_Reinj_1 4409 65750 40314 Mix4_TiO2_1_3 3472 Q8WVM8 Q8WVM8 Q8WVM8 >sp|Q8WVM8|SCFD1_HUMAN Sec1 family domain-containing protein 1 OS=Homo sapiens GN=SCFD1 PE=1 SV=4 0.46347 0 0.0175891 -17.392 2.56485E-10 128.38 0 0 0.00321542 -24.8996 3.66129E-10 124.5 0 0 0 0 0.46347 0 0.128494 46.976 1 S RVNLEESSGVENS NEK6 0.076 2.56485E-10 128.38 _VNLEEpSSGVENSPAGARPK_ VNLEES(0.463)S(0.463)GVENS(0.073)PAGARPK VNLEES(0)S(0)GVENS(-8.02)PAGARPK 6 3 674.31603 0.68172 0 0 0 0 0 0 0 0 1878 1318 298 298 6507 7445 65748 40312 Mix4_InSol_Tio2_Reinj_1 4409 65750 40314 Mix4_TiO2_1_3 3472 Q8WVM8 Q8WVM8 Q8WVM8 >sp|Q8WVM8|SCFD1_HUMAN Sec1 family domain-containing protein 1 OS=Homo sapiens GN=SCFD1 PE=1 SV=4 0.46347 0 0.0175891 -17.392 2.56485E-10 128.38 0 0 0.00321542 -24.8996 3.66129E-10 124.5 0 0 0 0 0.46347 0 0.128494 46.976 1 S VNLEESSGVENSP CK2 0.117 2.56485E-10 128.38 _VNLEEpSSGVENSPAGARPK_ VNLEES(0.463)S(0.463)GVENS(0.073)PAGARPK VNLEES(0)S(0)GVENS(-8.02)PAGARPK 7 3 674.31603 0.68172 0 0 0 0 0 0 0 0 1879 1318 303 303 6507 7445 65752 40316 Mix4_TiO2_Reinj_1_3 4098 65750 40314 Mix4_TiO2_1_3 3472 Q8WVM8 Q8WVM8 Q8WVM8 >sp|Q8WVM8|SCFD1_HUMAN Sec1 family domain-containing protein 1 OS=Homo sapiens GN=SCFD1 PE=1 SV=4 0.999968 45.6941 0.998897 29.5941 2.56485E-10 128.38 0 0 0.999968 45.6941 3.66129E-10 124.5 0 0 0 0 0.0730609 -8.02336 0.128494 46.976 1 S SSGVENSPAGARP Proline-directed 0.05 2.56485E-10 128.38 _VNLEESSGVENpSPAGARPK_ VNLEESSGVENS(1)PAGARPK VNLEES(-52.92)S(-45.69)GVENS(45.69)PAGARPK 12 2 1010.9704 -0.63442 871780 228680 0 0 643110 0 0 0 1880 1319 1461 1461 3008 3422 28756 17911 Mix4_TiO2_2_4 3344 28756 17911 Mix4_TiO2_2_4 3344 Q8WWI1;Q8WWI1-2;Q8WWI1-4;Q8WWI1-3 Q8WWI1 Q8WWI1 >sp|Q8WWI1|LMO7_HUMAN LIM domain only protein 7 OS=Homo sapiens GN=LMO7 PE=1 SV=3;>sp|Q8WWI1-2|LMO7_HUMAN Isoform 2 of LIM domain only protein 7 OS=Homo sapiens GN=LMO7;>sp|Q8WWI1-4|LMO7_HUMAN Isoform 4 of LIM domain only protein 7 OS=Homo sapiens GN=LMO7; 1 39.9338 0 0 1 39.9338 0.0981732 39.934 0 0 1 S KKEQVPSGAELER CK2 0.117 0.0981732 39.934 _KEQVPpSGAELER_ KEQVPS(1)GAELER KEQVPS(39.93)GAELER 6 2 711.83486 -1.5534 64226 0 64226 0 0 0 0 0 1881 1319 1510 1510 4881 5551 46871 28677 Mix4_TiO2_Reinj_1_5 4419 46871 28677 Mix4_TiO2_Reinj_1_5 4419 Q8WWI1;Q8WWI1-2;Q8WWI1-4;Q8WWI1-3 Q8WWI1 Q8WWI1 >sp|Q8WWI1|LMO7_HUMAN LIM domain only protein 7 OS=Homo sapiens GN=LMO7 PE=1 SV=3;>sp|Q8WWI1-2|LMO7_HUMAN Isoform 2 of LIM domain only protein 7 OS=Homo sapiens GN=LMO7;>sp|Q8WWI1-4|LMO7_HUMAN Isoform 4 of LIM domain only protein 7 OS=Homo sapiens GN=LMO7; 0.999992 50.8341 0 0 0.999992 50.8341 0.0504002 50.834 1 S IMRRGESLDNLDS CAMK2;CHK1 0.0228 0.0504002 50.834 _RGEpSLDNLDSPR_ RGES(1)LDNLDSPR RGES(50.83)LDNLDS(-50.83)PR 4 2 719.81974 0.51378 107330 0 0 0 107330 0 0 0 1882 1319 1593 1593 5354 6095 51998 31833 Mix4_TiO2_1_5 1966 51999 31834 Mix4_TiO2_Reinj_1_5 2535 Q8WWI1;Q8WWI1-2;Q8WWI1-4;Q8WWI1-3 Q8WWI1 Q8WWI1 >sp|Q8WWI1|LMO7_HUMAN LIM domain only protein 7 OS=Homo sapiens GN=LMO7 PE=1 SV=3;>sp|Q8WWI1-2|LMO7_HUMAN Isoform 2 of LIM domain only protein 7 OS=Homo sapiens GN=LMO7;>sp|Q8WWI1-4|LMO7_HUMAN Isoform 4 of LIM domain only protein 7 OS=Homo sapiens GN=LMO7; 0.938008 17.6248 0.938008 17.6248 0.575073 19.136 0.743843 4.78276 0.00467826 78.325 1 S PTPRSHSPSASQS CAMK2;GSK3;PKA/AKT;Proline-directed 0.00111111 0.00467826 78.325 _SHpSPSASQSGSQLR_ S(0.011)HS(0.938)PS(0.016)AS(0.011)QS(0.011)GS(0.011)QLR S(-19.14)HS(17.62)PS(-17.62)AS(-19.14)QS(-19.14)GS(-19.14)QLR 3 2 754.8281 0.74288 88378 19078 0 0 69299 0 0 0 1883 1320 305 305 1586 1780 14549 8831 Mix4_TiO2_Reinj_1_5 3296 14549 8831 Mix4_TiO2_Reinj_1_5 3296 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6;Q8WWM7-7 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.515528 1.94177 0.479913 1.39327 0.464591 17.478 0.515528 1.94177 0.00758084 62.219 0 0 0.0173084 -17.0549 0.197605 31.798 1 S LAREIESSPQYRL 0.00758084 62.219 _EIEpSSPQYR_ EIES(0.516)S(0.33)PQY(0.155)R EIES(1.94)S(-1.94)PQY(-5.22)R 4 2 594.75027 -0.065305 209430 0 0 0 209430 0 0 0 1884 1320 594 594 1897 2142 17419 10458 Mix4_TiO2_Reinj_1_5 6489 17418 10457 Mix4_TiO2_1_5 5588 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.997621 27.3613 0.995856 26.8182 6.23095E-06 100.61 0.997621 27.3613 0.00135064 82.44 1 S TSEPMGSPVSSKT GSK3;Proline-directed 0.05 6.23095E-06 100.61 _EVDGLLTSEPMGpSPVSSK_ EVDGLLTSEPMGS(0.998)PVS(0.002)SK EVDGLLT(-43.62)S(-34.2)EPMGS(27.36)PVS(-27.36)S(-39.04)K 13 2 956.93411 -0.30845 163830 39801 0 0 124030 0 0 0 1885 1320 390 390 2357 2667 21825 13563 Mix4_TiO2_Reinj_1_5 2566 21825 13563 Mix4_TiO2_Reinj_1_5 2566 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.866605 8.12767 0.866605 8.12767 0.0663468 54.151 1 S PHHLDNSSPGPGS NEK6 0.076 0.0663468 54.151 _GPHHLDNpSSPGPGSEAR_ GPHHLDNS(0.867)S(0.133)PGPGSEAR GPHHLDNS(8.13)S(-8.13)PGPGS(-45.13)EAR 8 2 897.8814 -0.40882 44367 0 0 0 44367 0 0 0 1886 1320 391 391 2357 2667 21824 13562 Mix4_TiO2_Reinj_1_5 2534 21825 13563 Mix4_TiO2_Reinj_1_5 2566 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.738389 4.51409 0.738389 4.51409 0.0663468 54.151 1 S HHLDNSSPGPGSE Polo box;Proline-directed 0.00405 0.0663468 54.151 _GPHHLDNSpSPGPGSEAR_ GPHHLDNS(0.261)S(0.738)PGPGSEAR GPHHLDNS(-4.51)S(4.51)PGPGS(-31.97)EAR 9 3 598.92336 0.69319 103570 0 0 0 103570 0 0 0 1887 1320 111 111 2362;2391 2672;2710 21856 13589 Mix4_TiO2_Reinj_1_5 6001 21856 13589 Mix4_TiO2_Reinj_1_5 6001 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6;Q8WWM7-7 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 1 120.824 1 121.563 2.23637E-12 145.24 0 0 1 120.824 3.85767E-16 169.37 1 74.9642 4.29706E-11 122.87 0.999998 57.8117 0.00181028 84.763 1 S GKGPPQSPVFEGV ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.85767E-16 169.37 _GPPQpSPVFEGVYNNSR_ GPPQS(1)PVFEGVYNNSR GPPQS(120.82)PVFEGVY(-120.82)NNS(-143.32)R 5 2 914.40672 0.84398 2269300 15.064 427350 0 0 1020000 0 493960 327980 1888 1320 496 496 5084 5782 49176 30025 Mix4_TiO2_Reinj_1_5 7101 49176 30025 Mix4_TiO2_Reinj_1_5 7101 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.919379 11.62 0 0 0.919379 11.62 0.00107795 97.421 1 S GSISPASPKISLA CDK1;CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.00107795 97.421 _SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPApSPK_ SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS(0.017)IS(0.063)PAS(0.919)PK S(-76.79)AAPAPIS(-75.88)AS(-74.95)CPEPPIGS(-69.71)AVPT(-51.14)S(-51.14)S(-47.42)AS(-43.47)IPVT(-38.97)S(-38.97)S(-38.97)VS(-38.97)DPGVGS(-17.39)IS(-11.62)PAS(11.62)PK 45 4 1113.7937 -0.32295 809930 0 0 0 809930 0 0 0 1889 1320 680 680 5806 6618 57237 34879 Mix4_InSol_Tio2_Reinj_1 2522 57243 34889 Mix4_TiO2_Reinj_1_5 2180 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.787579 12.6807 1.97949E-06 -54.307 0.0308764 54.307 0.000952204 -27.4088 0.234141 27.409 0.457839 0.100134 0.00362774 78.096 0.102467 -6.77535 0.0429911 44.679 0.787579 12.6807 0.0199227 54.307 1 S SVNKSTSTPTSPG CHK1;GSK3;PKD 0.020748 0.00362774 78.096 _STpSTPTSPGPR_ S(0.042)T(0.042)S(0.788)T(0.042)PT(0.042)S(0.042)PGPR S(-12.68)T(-12.68)S(12.68)T(-12.68)PT(-12.68)S(-12.68)PGPR 3 2 584.25572 -0.29085 18348 0 0 0 0 0 0 18348 1890 1320 684 684 5806 6618 57238 34880 Mix4_InSol_Tio2_Reinj_1 2291 57243 34889 Mix4_TiO2_Reinj_1_5 2180 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.93123 11.3175 0.53365 0.585537 0.0308764 54.307 0.471849 -0.458109 0.234141 27.409 0.376217 -2.19595 0.00362774 78.096 0.817342 7.9283 0.0429911 44.679 0.93123 11.3175 0.0199227 54.307 1 S STSTPTSPGPRTH CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00362774 78.096 _STSTPTpSPGPR_ STSTPT(0.069)S(0.931)PGPR S(-54.31)T(-54.31)S(-54.31)T(-54.31)PT(-11.32)S(11.32)PGPR 7 2 584.25572 0.29575 321740 232100 0 0 0 0 48750 40895 1891 1320 634 634 5974 6814 58990 35790 Mix4_TiO2_1_5 5315 58990 35790 Mix4_TiO2_1_5 5315 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.75268 5.20408 0.75268 5.20408 0.00270385 92.528 0.746054 5.07599 0.0049233 87.323 1 S CPSQTGSPPVGLI CK1;Proline-directed 0.05 0.00270385 92.528 _TESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGpSPPVGLIK_ TESVSDKEDKPPLAPSGGTEGPEQPPPPCPS(0.02)QT(0.227)GS(0.753)PPVGLIK T(-64.76)ES(-64.76)VS(-61.07)DKEDKPPLAPS(-65.14)GGT(-65.14)EGPEQPPPPCPS(-15.71)QT(-5.2)GS(5.2)PPVGLIK 35 4 1087.02 -0.29314 2447100 626440 0 0 1820700 0 0 0 1892 1320 423 423 6094 6955 60252 36478 Mix4_TiO2_Reinj_1_5 4701 60252 36478 Mix4_TiO2_Reinj_1_5 4701 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.424035 0 0.243357 0 0.282943 40.597 0.424035 0 0.0106388 68.652 1 S RGAKTLSSPSNRP 0.0106388 68.652 _TLpSSPSNRPSGETSVPPPPAVGR_ T(0.074)LS(0.424)S(0.424)PS(0.074)NRPS(0.004)GETSVPPPPAVGR T(-7.59)LS(0)S(0)PS(-7.59)NRPS(-20.2)GET(-38.04)S(-43.66)VPPPPAVGR 3 3 790.71983 0.2087 0 0 0 0 0 0 0 0 1893 1320 424 424 6094 6955 60252 36478 Mix4_TiO2_Reinj_1_5 4701 60252 36478 Mix4_TiO2_Reinj_1_5 4701 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.424035 0 0.243357 0 0.282943 40.597 0.424035 0 0.0106388 68.652 1 S GAKTLSSPSNRPS Polo box;Proline-directed 0.00405 0.0106388 68.652 _TLpSSPSNRPSGETSVPPPPAVGR_ T(0.074)LS(0.424)S(0.424)PS(0.074)NRPS(0.004)GETSVPPPPAVGR T(-7.59)LS(0)S(0)PS(-7.59)NRPS(-20.2)GET(-38.04)S(-43.66)VPPPPAVGR 4 3 790.71983 0.2087 0 0 0 0 0 0 0 0 1894 1320 426 426 6094 6955 60251 36477 Mix4_TiO2_1_5 4089 60252 36478 Mix4_TiO2_Reinj_1_5 4701 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.243357 0 0.243357 0 0.282943 40.597 0.0738981 -7.58768 0.0106388 68.652 1 S KTLSSPSNRPSGE CK1;GSK3 0.081 0.0106388 68.652 _pTLSSPSNRPSGETSVPPPPAVGR_ T(0.243)LS(0.243)S(0.243)PS(0.243)NRPS(0.017)GET(0.005)S(0.005)VPPPPAVGR T(0)LS(0)S(0)PS(0)NRPS(-11.55)GET(-17.08)S(-17.08)VPPPPAVGR 6 3 790.71983 0.43978 0 0 0 0 0 0 0 0 1895 1321 557 557 3163 3590 30007 18654 Mix4_TiO2_Reinj_1_3 9028 30007 18654 Mix4_TiO2_Reinj_1_3 9028 Q8WX92 Q8WX92 Q8WX92 >sp|Q8WX92|NELFB_HUMAN Negative elongation factor B OS=Homo sapiens GN=COBRA1 PE=1 SV=1 0.999846 38.1308 0.965678 14.4926 0.00566061 75.286 0.999846 38.1308 0.000148232 90.506 1 S LDHRKPSPAQAAE CAMK2;PKA;Proline-directed 0.004788 0.000148232 90.506 _KPpSPAQAAETPALELPLPSVPAPAPL_ KPS(1)PAQAAETPALELPLPSVPAPAPL KPS(38.13)PAQAAET(-38.13)PALELPLPS(-87.01)VPAPAPL 3 3 881.46622 0.51646 450290 174710 0 0 275580 0 0 0 1896 1322 893 893 2705 3081 25544 15782 Mix4_TiO2_1_3 2801 25544 15782 Mix4_TiO2_1_3 2801 Q8WX93;Q8WX93-5;Q8WX93-2;Q8WX93-3;Q8WX93-4 Q8WX93 Q8WX93 >sp|Q8WX93|PALLD_HUMAN Palladin OS=Homo sapiens GN=PALLD PE=1 SV=2;>sp|Q8WX93-5|PALLD_HUMAN Isoform 5 of Palladin OS=Homo sapiens GN=PALLD;>sp|Q8WX93-2|PALLD_HUMAN Isoform 2 of Palladin OS=Homo sapiens GN=PALLD;>sp|Q8WX93-3|PALLD_HUMAN Isoform 140-kDa of P 1 81.964 1 81.964 0.00283004 81.964 1 S RTARIASDEEIQG CAMK2;CK2 0.042 0.00283004 81.964 _IApSDEEIQGTK_ IAS(1)DEEIQGTK IAS(81.96)DEEIQGT(-81.96)K 3 2 635.78177 -1.3769 32212 32212 0 0 0 0 0 0 1897 1323 221 221 3286 3721 31051 19258 Mix4_InSol_TiO2_2 3378 31054 19261 Mix4_TiO2_1_3 3513 Q8WXE1;Q8WXE1-2;Q8WXE1-3 Q8WXE1 Q8WXE1 >sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein OS=Homo sapiens GN=ATRIP PE=1 SV=1;>sp|Q8WXE1-2|ATRIP_HUMAN Isoform 2 of ATR-interacting protein OS=Homo sapiens GN=ATRIP;>sp|Q8WXE1-3|ATRIP_HUMAN Isoform 3 of ATR-interacting protein OS=Homo sapiens GN=ATRIP 0.665717 3.05615 0.112502 -8.89401 0.00426248 87.618 0 0 0.00304845 -25.1446 0.0628304 47.315 0.665717 3.05615 0.331545 21.313 0.00255632 -25.9124 0.0483672 51.409 1 S LAAPSVSHVSPRK 0.00426248 87.618 _LAAPSVpSHVSPR_ LAAPS(0.005)VS(0.666)HVS(0.329)PR LAAPS(-21.31)VS(3.06)HVS(-3.06)PR 7 2 650.8241 0.10646 25338 0 0 0 0 0 25338 0 1898 1323 224 224 3286 3721 31054 19261 Mix4_TiO2_1_3 3513 31054 19261 Mix4_TiO2_1_3 3513 Q8WXE1;Q8WXE1-2;Q8WXE1-3 Q8WXE1 Q8WXE1 >sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein OS=Homo sapiens GN=ATRIP PE=1 SV=1;>sp|Q8WXE1-2|ATRIP_HUMAN Isoform 2 of ATR-interacting protein OS=Homo sapiens GN=ATRIP;>sp|Q8WXE1-3|ATRIP_HUMAN Isoform 3 of ATR-interacting protein OS=Homo sapiens GN=ATRIP 0.999594 34.4784 0.999594 34.4784 0.00426248 87.618 0 0 0.99665 25.1446 0.0628304 47.315 0.329363 -3.05615 0.331545 21.313 0.997378 25.9124 0.0483672 51.409 1 S PSVSHVSPRKNPS CDK1;CDK2;CK1;Proline-directed 0.0057 0.00426248 87.618 _LAAPSVSHVpSPR_ LAAPSVSHVS(1)PR LAAPS(-43.07)VS(-34.48)HVS(34.48)PR 10 2 650.8241 0.45468 806550 284540 0 0 499910 0 0 22104 1899 1325 4108 4108 4893 5564 46993 28743 Mix4_TiO2_Reinj_1_1 7774 46993 28743 Mix4_TiO2_Reinj_1_1 7774 Q8WXH0-2;Q8WXH0;Q8WXH0-7 Q8WXH0-2 Q8WXH0-2 >sp|Q8WXH0-2|SYNE2_HUMAN Isoform 2 of Nesprin-2 OS=Homo sapiens GN=SYNE2;>sp|Q8WXH0|SYNE2_HUMAN Nesprin-2 OS=Homo sapiens GN=SYNE2 PE=1 SV=3;>sp|Q8WXH0-7|SYNE2_HUMAN Isoform Gamma of Nesprin-2 OS=Homo sapiens GN=SYNE2 0.333333 0 0 0 0.333333 0 2.47399E-07 115.64 1 S KLNRRGSMSYLAA AURORA;AURORA-A;CAMK2;CHK1;CHK1/2;PKA;PKA/AKT;PKD 0.00111111 2.47399E-07 115.64 _RGpSM(ox)SYLAAVEEEVEESSVK_ RGS(0.333)MS(0.333)Y(0.333)LAAVEEEVEESSVK RGS(0)MS(0)Y(0)LAAVEEEVEES(-115.64)S(-115.64)VK 3 3 766.00653 0.36754 0 0 0 0 0 0 0 0 1900 1325 4110 4110 4893 5564 46993 28743 Mix4_TiO2_Reinj_1_1 7774 46993 28743 Mix4_TiO2_Reinj_1_1 7774 Q8WXH0-2;Q8WXH0;Q8WXH0-7 Q8WXH0-2 Q8WXH0-2 >sp|Q8WXH0-2|SYNE2_HUMAN Isoform 2 of Nesprin-2 OS=Homo sapiens GN=SYNE2;>sp|Q8WXH0|SYNE2_HUMAN Nesprin-2 OS=Homo sapiens GN=SYNE2 PE=1 SV=3;>sp|Q8WXH0-7|SYNE2_HUMAN Isoform Gamma of Nesprin-2 OS=Homo sapiens GN=SYNE2 0.333333 0 0 0 0.333333 0 2.47399E-07 115.64 1 S NRRGSMSYLAAVE 2.47399E-07 115.64 _RGpSM(ox)SYLAAVEEEVEESSVK_ RGS(0.333)MS(0.333)Y(0.333)LAAVEEEVEESSVK RGS(0)MS(0)Y(0)LAAVEEEVEES(-115.64)S(-115.64)VK 5 3 766.00653 0.36754 0 0 0 0 0 0 0 0 1901 1326 844 844 5882 6709 58013 35246 Mix4_TiO2_1_3 2755 58015 35248 Mix4_TiO2_Reinj_1_3 3301 Q8WY36;Q8WY36-2 Q8WY36 Q8WY36 >sp|Q8WY36|BBX_HUMAN HMG box transcription factor BBX OS=Homo sapiens GN=BBX PE=1 SV=1;>sp|Q8WY36-2|BBX_HUMAN Isoform BBXa of HMG box transcription factor BBX OS=Homo sapiens GN=BBX 0.98767 19.6577 0.98767 19.6577 0.60729 27.788 0 0 0.978722 16.6285 0.07079 53.766 0 0 0 0 1 S TADGRVSPAGGTL PKA;Proline-directed 0.042 0.07079 53.766 _TADGRVpSPAGGTLDDKPK_ T(0.011)ADGRVS(0.988)PAGGT(0.002)LDDKPK T(-19.66)ADGRVS(19.66)PAGGT(-27.79)LDDKPK 7 3 622.2982 -0.093974 415950 42667 0 0 373290 0 0 0 1902 1327 1249 1249 5796 6602 57091 34823 Mix4_InSol_Tio2_Reinj_1 3877 57095 34827 Mix4_TiO2_Reinj_1_1 3097 Q8WYP5-2;Q8WYP5 Q8WYP5-2 Q8WYP5-2 >sp|Q8WYP5-2|ELYS_HUMAN Isoform 2 of Protein ELYS OS=Homo sapiens GN=AHCTF1;>sp|Q8WYP5|ELYS_HUMAN Protein ELYS OS=Homo sapiens GN=AHCTF1 PE=1 SV=3 0.264519 0.687969 0.0631976 -8.17571 0.564455 27.78 0.258358 -0.673256 6.06655E-09 120.86 0.214594 -4.78907 0.222697 38.854 0.264519 0.687969 1.23821 7.6634 1 S RSTPLASPSPSPG CK1;GSK3;Proline-directed 0.05 6.06655E-09 120.86 _STPLApSPSPSPGRSPQR_ S(0.045)T(0.045)PLAS(0.265)PS(0.226)PS(0.226)PGRS(0.193)PQR S(-7.66)T(-7.66)PLAS(0.69)PS(-0.69)PS(-0.69)PGRS(-1.36)PQR 6 3 601.29127 -0.34369 0 0 0 0 0 0 0 0 1903 1327 1251 1251 5796 6602 57092 34824 Mix4_TiO2_1_1 2660 57095 34827 Mix4_TiO2_Reinj_1_1 3097 Q8WYP5-2;Q8WYP5 Q8WYP5-2 Q8WYP5-2 >sp|Q8WYP5-2|ELYS_HUMAN Isoform 2 of Protein ELYS OS=Homo sapiens GN=AHCTF1;>sp|Q8WYP5|ELYS_HUMAN Protein ELYS OS=Homo sapiens GN=AHCTF1 PE=1 SV=3 0.969808 16.5916 0.969808 16.5916 0.564455 27.78 0.337872 4.06781 6.06655E-09 120.86 0.0236618 -14.3648 0.222697 38.854 0.225766 -0.687969 1.23821 7.6634 1 S TPLASPSPSPGRS Proline-directed 0.05 6.06655E-09 120.86 _STPLASPpSPSPGRSPQR_ S(0.002)T(0.002)PLAS(0.004)PS(0.97)PS(0.021)PGRS(0.002)PQR S(-27.78)T(-27.78)PLAS(-23.76)PS(16.59)PS(-16.59)PGRS(-27.78)PQR 8 2 901.43326 0.63225 24783 24783 0 0 0 0 0 0 1904 1327 1253 1253 5796 6602 57090 34822 Mix4_InSol_TiO2_1 3906 57095 34827 Mix4_TiO2_Reinj_1_1 3097 Q8WYP5-2;Q8WYP5 Q8WYP5-2 Q8WYP5-2 >sp|Q8WYP5-2|ELYS_HUMAN Isoform 2 of Protein ELYS OS=Homo sapiens GN=AHCTF1;>sp|Q8WYP5|ELYS_HUMAN Protein ELYS OS=Homo sapiens GN=AHCTF1 PE=1 SV=3 0.646435 4.78907 0.415213 0 0.564455 27.78 0.301681 0.673256 6.06655E-09 120.86 0.646435 4.78907 0.222697 38.854 0.225766 -0.687969 1.23821 7.6634 1 S LASPSPSPGRSPQ CDK1;CDK2;CK1;GSK3;Proline-directed 0.0057 6.06655E-09 120.86 _STPLASPSPpSPGRSPQR_ S(0.007)T(0.008)PLAS(0.215)PS(0.024)PS(0.646)PGRS(0.101)PQR S(-19.81)T(-19.07)PLAS(-4.79)PS(-14.36)PS(4.79)PGRS(-8.08)PQR 10 2 901.43326 0.16452 70791 0 0 0 0 0 70791 0 1905 1327 1257 1257 5796 6602 57095 34827 Mix4_TiO2_Reinj_1_1 3097 57095 34827 Mix4_TiO2_Reinj_1_1 3097 Q8WYP5-2;Q8WYP5 Q8WYP5-2 Q8WYP5-2 >sp|Q8WYP5-2|ELYS_HUMAN Isoform 2 of Protein ELYS OS=Homo sapiens GN=AHCTF1;>sp|Q8WYP5|ELYS_HUMAN Protein ELYS OS=Homo sapiens GN=AHCTF1 PE=1 SV=3 0.967642 15.0068 0.415213 0 0.564455 27.78 0.967642 15.0068 6.06655E-09 120.86 0.100543 -8.08172 0.222697 38.854 0.193345 -1.36123 1.23821 7.6634 1 S SPSPGRSPQRLKE CDK1;CDK2;CK1;Proline-directed 0.0057 6.06655E-09 120.86 _STPLASPSPSPGRpSPQR_ STPLASPS(0.002)PS(0.031)PGRS(0.968)PQR S(-89.86)T(-88.87)PLAS(-44.09)PS(-27.38)PS(-15.01)PGRS(15.01)PQR 14 2 901.43326 -0.052894 85364 0 0 0 85364 0 0 0 1906 1328 26497 26497 1878 2121 17273 10385 Mix4_TiO2_Reinj_1_2 6973 17273 10385 Mix4_TiO2_Reinj_1_2 6973 Q8WZ42-8;Q8WZ42;Q8WZ42-2;Q8WZ42-7;Q8WZ42-4;Q8WZ42-5;Q8WZ42-3 Q8WZ42-8 Q8WZ42-8 >sp|Q8WZ42-8|TITIN_HUMAN Isoform Cardiac novex-1 of Titin OS=Homo sapiens GN=TTN;>sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens GN=TTN PE=1 SV=2;>sp|Q8WZ42-2|TITIN_HUMAN Isoform 2 of Titin OS=Homo sapiens GN=TTN;>sp|Q8WZ42-7|TITIN_HUMAN Isoform Cardiac novex 0.498668 0 0.498668 0 0.0109083 69.801 1 S RVNVSSSKTVTSL 0.0109083 69.801 _ETTRVNVSSpSKTVTSLSIK_ ETTRVNVSSS(0.499)KT(0.499)VTSLS(0.001)IK ET(-59.55)T(-59.55)RVNVS(-30.06)S(-30.96)S(0)KT(0)VT(-30.02)S(-30.02)LS(-28.07)IK 10 2 1059.0461 1.3097 0 0 0 0 0 0 0 0 1907 1332 275 275 1623 1822;1823 14928 9038 Mix4_TiO2_Reinj_1_4 1535 14928 9038 Mix4_TiO2_Reinj_1_4 1535 Q92504 Q92504 Q92504 >sp|Q92504|S39A7_HUMAN Zinc transporter SLC39A7 OS=Homo sapiens GN=SLC39A7 PE=1 SV=2 1 114.502 0 0 1 114.502 0.000155399 114.5 2 S STKEKQSSEEEEK CK2 0.117 0.000155399 114.5 _EKQpSpSEEEEKETR_ EKQS(1)S(1)EEEEKETR EKQS(114.5)S(114.5)EEEEKET(-114.5)R 4 2 884.83734 0.26431 1603300 0 0 0 1603300 0 0 0 1908 1332 276 276 1623 1822;1823 14928 9038 Mix4_TiO2_Reinj_1_4 1535 14928 9038 Mix4_TiO2_Reinj_1_4 1535 Q92504 Q92504 Q92504 >sp|Q92504|S39A7_HUMAN Zinc transporter SLC39A7 OS=Homo sapiens GN=SLC39A7 PE=1 SV=2 1 114.502 0 0 1 114.502 0.000155399 114.5 2 S TKEKQSSEEEEKE CK2 0.117 0.000155399 114.5 _EKQpSpSEEEEKETR_ EKQS(1)S(1)EEEEKETR EKQS(114.5)S(114.5)EEEEKET(-114.5)R 5 2 884.83734 0.26431 1603300 0 0 0 1603300 0 0 0 1909 1333 906 906 1102 1240 10375 6390 Mix4_TiO2_1_1 3156 10375 6390 Mix4_TiO2_1_1 3156 Q92508 Q92508 Q92508 >sp|Q92508|FA38A_HUMAN Protein FAM38A OS=Homo sapiens GN=FAM38A PE=1 SV=3 0.99961 34.9433 0.99961 34.9433 0.0137872 68.782 0 0 1 S LEPGPDSPGGSSP ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.0137872 68.782 _DPGLEPGPDpSPGGSSPPR_ DPGLEPGPDS(1)PGGSSPPR DPGLEPGPDS(34.94)PGGS(-34.94)S(-41.54)PPR 10 2 899.88581 -0.32813 24030 24030 0 0 0 0 0 0 1910 1333 1134 1134 5323 6059 51665 31631 Mix4_TiO2_Reinj_1_1 2690 51665 31631 Mix4_TiO2_Reinj_1_1 2690 Q92508 Q92508 Q92508 >sp|Q92508|FA38A_HUMAN Protein FAM38A OS=Homo sapiens GN=FAM38A PE=1 SV=3 0.5 0 0.423462 -1.34009 0.0572557 50.373 0 0 0.5 0 0.0015763 94.288 0 0 0 0 0 0 1 S TGYHTRSGSEEAV CK2 0.117 0.0015763 94.288 _pSGSEEAVTDPGER_ S(0.5)GS(0.5)EEAVTDPGER S(0)GS(0)EEAVT(-92.51)DPGER 1 2 707.28012 0.23314 137030 0 0 0 137030 0 0 0 1911 1333 1136 1136 5323 6059 51664 31630 Mix4_TiO2_1_1 2134 51665 31631 Mix4_TiO2_Reinj_1_1 2690 Q92508 Q92508 Q92508 >sp|Q92508|FA38A_HUMAN Protein FAM38A OS=Homo sapiens GN=FAM38A PE=1 SV=3 0.576532 1.34009 0.576532 1.34009 0.0572557 50.373 0 0 0.5 0 0.0015763 94.288 0 0 0 0 0 0 1 S YHTRSGSEEAVTD CAMK2;CK1 0.042 0.0015763 94.288 _SGpSEEAVTDPGER_ S(0.423)GS(0.577)EEAVTDPGER S(-1.34)GS(1.34)EEAVT(-50.37)DPGER 3 2 707.28012 -0.15472 183750 46720 0 0 137030 0 0 0 1912 1333 1161 1161 5899 6728 58161 35323 Mix4_TiO2_Reinj_1_1 5772 58161 35323 Mix4_TiO2_Reinj_1_1 5772 Q92508 Q92508 Q92508 >sp|Q92508|FA38A_HUMAN Protein FAM38A OS=Homo sapiens GN=FAM38A PE=1 SV=3 0.996626 24.7036 0.992866 21.4357 0.0013197 77.87 0.996626 24.7036 0.00181641 92.89 0 0 0 0 0.883758 8.80969 0.723115 8.8097 1 S GLMRTASELLLDR CAMK2;CHK1;CHK1/2;PKD 0.003192 0.00181641 92.89 _TApSELLLDR_ T(0.003)AS(0.997)ELLLDR T(-24.7)AS(24.7)ELLLDR 3 2 549.26555 -0.03248 356320 62048 0 0 274480 0 0 19789 1913 1336 152 152 387 443 3703 2213 Mix4_TiO2_Reinj_1_6 3839 3699 2202 Mix4_TiO2_Reinj_1_2 3228 Q92530 Q92530 Q92530 >sp|Q92530|PSMF1_HUMAN Proteasome inhibitor PI31 subunit OS=Homo sapiens GN=PSMF1 PE=1 SV=2 0.499097 0 0 0 0.499097 0 0.0218581 63.172 0.220009 -5.13944 1.08524 10.671 0 0 1 S WEKANVSSPHREF 0.0218581 63.172 _ANVpSSPHREFPPATAR_ ANVS(0.499)S(0.499)PHREFPPAT(0.002)AR ANVS(0)S(0)PHREFPPAT(-24.41)AR 4 3 606.28786 0.10366 0 0 0 0 0 0 0 0 1914 1336 153 153 387 443 3701 2210 Mix4_TiO2_Reinj_1_2 3914 3699 2202 Mix4_TiO2_Reinj_1_2 3228 Q92530 Q92530 Q92530 >sp|Q92530|PSMF1_HUMAN Proteasome inhibitor PI31 subunit OS=Homo sapiens GN=PSMF1 PE=1 SV=2 0.922317 10.7461 0 0 0.922317 10.7461 0.0218581 63.172 0.718432 5.13944 1.08524 10.671 0 0 1 S EKANVSSPHREFP CDK1;CDK2;ERK/MAPK;Polo box;Proline-directed 0.0034 0.0218581 63.172 _ANVSpSPHREFPPATAR_ ANVS(0.078)S(0.922)PHREFPPATAR ANVS(-10.75)S(10.75)PHREFPPAT(-49.83)AR 5 3 606.28786 0.22524 704920 0 0 0 599330 0 105590 0 1915 1337 1778 1778 82 97;98 947 618 Mix4_TiO2_1_1 1963 953 624 Mix4_TiO2_Reinj_1_5 2582 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.49028 0.458633 0.49028 0.458633 0.0181123 65.73 0.422491 5.22802 0.505532 29.686 0.27208 -2.21927 0.0270654 59.865 0.0463244 -13.0624 0.278817 37.016 1 S ESPRAASSSSPGS CAMK2 0.042 6.80962E-06 105.19 _AApSSSSPGSPVASSPSR_ AAS(0.49)S(0.441)S(0.058)S(0.01)PGSPVASSPSR AAS(0.46)S(-0.46)S(-9.27)S(-16.7)PGS(-39.98)PVAS(-65.73)S(-65.73)PS(-65.73)R 3 2 806.35415 -0.37759 0 0 0 0 0 0 0 0 1916 1337 1780 1780 82 97;98 943 614 Mix4_InSol_TiO2_1 3038 953 624 Mix4_TiO2_Reinj_1_5 2582 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.453548 2.21927 0.303174 0 0.0181123 65.73 0.27487 -5.22802 0.505532 29.686 0.453548 2.21927 0.0270654 59.865 0.00122271 -28.8473 0.278817 37.016 1 S PRAASSSSPGSPV GSK3 0.081 6.80962E-06 105.19 _AASSpSSPGSPVASSPSR_ AAS(0.272)S(0.219)S(0.454)S(0.055)PGS(0.001)PVASSPSR AAS(-2.22)S(-3.17)S(2.22)S(-9.17)PGS(-26.9)PVAS(-59.43)S(-59.87)PS(-59.87)R 5 2 806.35415 -0.28869 0 0 0 0 0 0 0 0 1917 1337 1784 1784 82 97;98 953 624 Mix4_TiO2_Reinj_1_5 2582 953 624 Mix4_TiO2_Reinj_1_5 2582 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.999994 55.732 0.999273 32.5047 0.0181123 65.73 0.999994 55.732 6.80962E-06 105.19 0.999095 36.419 0.0270654 59.865 0.937672 13.0624 0.278817 37.016 1 S SSSSPGSPVASSP CK1;ERK/MAPK;GSK3;Proline-directed 0.0025 6.80962E-06 105.19 _AASSSSPGpSPVASSPSR_ AASSSSPGS(1)PVASSPSR AAS(-78.51)S(-64.51)S(-57.27)S(-58.37)PGS(55.73)PVAS(-55.73)S(-74.43)PS(-84.89)R 9 2 806.35415 -0.31826 278670 46393 0 0 152210 0 42610 37454 1918 1337 1789 1789 82 97;98 954 625 Mix4_TiO2_Reinj_1_5 2728 953 624 Mix4_TiO2_Reinj_1_5 2582 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.895064 9.6158 0.822741 7.41117 0.0181123 65.73 0.895064 9.6158 6.80962E-06 105.19 9.01444E-05 -40.4467 0.0270654 59.865 0.000186387 -37.0164 0.278817 37.016 1 S GSPVASSPSRLSP CDK1;CDK2;Polo box;Proline-directed 0.00405 6.80962E-06 105.19 _AASSSSPGSPVASpSPSR_ AASSSSPGSPVAS(0.098)S(0.895)PS(0.007)R AAS(-74.6)S(-74.6)S(-74.6)S(-74.6)PGS(-49.32)PVAS(-9.62)S(9.62)PS(-20.98)R 14 2 806.35415 -0.33907 231850 49257 0 0 182600 0 0 0 1919 1337 1298 1298 105 121 1069 683 Mix4_TiO2_Reinj_1_5 5441 1070 684 Mix4_TiO2_Reinj_1_5 5448 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.999477 32.8928 0.992055 20.9709 0.00423928 76.424 0.888329 9.10451 0.000512981 79.406 0.999477 32.8928 7.38743E-18 141.46 0 0 0.954757 13.2676 2.25525E-07 107.16 0.938218 11.815 0.000120017 92.094 1 S PDAGAQSDSELPS CK2 0.117 7.38743E-18 141.46 _ADAPDAGAQpSDSELPSYHQNDVSLDR_ ADAPDAGAQS(0.999)DS(0.001)ELPSYHQNDVSLDR ADAPDAGAQS(32.89)DS(-32.89)ELPS(-53.14)Y(-53.51)HQNDVS(-79.11)LDR 10 2 1419.5961 -0.9434 13838000 4.8301 1679300 266720 0 9301500 0 1463100 1127300 1920 1337 1300 1300 105 121 1067 680 Mix4_TiO2_Reinj_1_1 4883 1070 684 Mix4_TiO2_Reinj_1_5 5448 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.562266 1.08741 0.1962 -6.11928 0.00423928 76.424 0.156873 -7.2258 0.000512981 79.406 0.562266 1.08741 7.38743E-18 141.46 0 0 0.499973 0 2.25525E-07 107.16 0.252707 -0.629503 0.000120017 92.094 1 S AGAQSDSELPSYH GSK3 0.081 7.38743E-18 141.46 _ADAPDAGAQSDpSELPSYHQNDVSLDR_ ADAPDAGAQS(0.438)DS(0.562)ELPSYHQNDVSLDR ADAPDAGAQS(-1.09)DS(1.09)ELPS(-48.73)Y(-53.61)HQNDVS(-89.5)LDR 12 3 946.73319 -1.5493 5952700 2.0778 0 0 0 4587800 0 1364900 0 1921 1337 1311 1311 105 121 1061 673 Mix4_InSol_Tio2_Reinj_2 4292 1070 684 Mix4_TiO2_Reinj_1_5 5448 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.292124 0.629503 3.44106E-05 -43.6794 0.00423928 76.424 0.000775802 -30.5882 0.000512981 79.406 5.15633E-05 -42.4108 7.38743E-18 141.46 0 0 4.71823E-05 -43.0611 2.25525E-07 107.16 0.292124 0.629503 0.000120017 92.094 1 S YHQNDVSLDRGYT PLK1 0.033462 7.38743E-18 141.46 _ADAPDAGAQSDSELPSYHQNDVpSLDR_ ADAPDAGAQS(0.253)DS(0.253)ELPS(0.101)Y(0.101)HQNDVS(0.292)LDR ADAPDAGAQS(-0.63)DS(-0.63)ELPS(-4.6)Y(-4.6)HQNDVS(0.63)LDR 23 3 946.73319 -0.39211 0 0 0 0 0 0 0 0 0 1922 1337 1318 1318 2549;2550 2894;2895 23855 14812 Mix4_TiO2_Reinj_1_1 3497 23859 14817 Mix4_TiO2_Reinj_1_5 4020 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.996876 28.3106 0.912449 11.7238 0.00384171 79.117 0 0 0.996876 28.3106 2.70746E-09 130.01 0 0 0.966546 16.1622 0.47153 30.785 0.940089 16.9603 0.574289 27.487 1 S LDRGYTSDSEVYT CK2 0.117 2.70746E-09 130.01 _GYTpSDSEVYTDHGRPGK_ GYT(0.001)S(0.997)DS(0.001)EVYTDHGRPGK GY(-54.66)T(-28.31)S(28.31)DS(-28.31)EVY(-37.49)T(-61.85)DHGRPGK 4 3 650.27394 0.093343 8970300 510910 0 0 7654200 0 468870 336300 1923 1337 1320 1320 2549;2550 2894;2895 23857 14815 Mix4_TiO2_Reinj_1_2 3439 23859 14817 Mix4_TiO2_Reinj_1_5 4020 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.690094 8.45262 0.328284 -0.0543241 0.00384171 79.117 0 0 0.690094 8.45262 2.70746E-09 130.01 0 0 0.0233886 -16.1622 0.47153 30.785 0.0189294 -16.9603 0.574289 27.487 1 S RGYTSDSEVYTDH 2.70746E-09 130.01 _GYTSDpSEVYTDHGRPGK_ GY(0.038)T(0.038)S(0.099)DS(0.69)EVY(0.099)T(0.038)DHGRPGK GY(-12.64)T(-12.64)S(-8.45)DS(8.45)EVY(-8.45)T(-12.64)DHGRPGK 6 3 650.27394 -0.087847 38860 0 0 0 38860 0 0 0 1924 1337 662 662 5284 6013 51259 31399 Mix4_TiO2_Reinj_1_5 5302 51259 31399 Mix4_TiO2_Reinj_1_5 5302 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.99951 33.0997 0 0 0.99951 33.0997 0.0195252 64.543 1 S HGKSGCSDLEEAV CK1;CK2 0.081 0.0195252 64.543 _SGCpSDLEEAVDSGADKK_ SGCS(1)DLEEAVDSGADKK S(-33.1)GCS(33.1)DLEEAVDS(-64.22)GADKK 4 3 616.58368 0.097752 84270 0.74057 0 0 0 84270 0 0 0 1925 1338 735 735 616 709 5835 3445 Mix4_TiO2_Reinj_1_5 4640 5835 3445 Mix4_TiO2_Reinj_1_5 4640 Q92540-4;Q92540;Q92540-2 Q92540-4 Q92540-4 >sp|Q92540-4|SMG7_HUMAN Isoform 4 of Protein SMG7 OS=Homo sapiens GN=SMG7;>sp|Q92540|SMG7_HUMAN Protein SMG7 OS=Homo sapiens GN=SMG7 PE=1 SV=2;>sp|Q92540-2|SMG7_HUMAN Isoform 2 of Protein SMG7 OS=Homo sapiens GN=SMG7 0.992338 21.1772 0.49755 0 1.37188 26.495 0 0 0.992338 21.1772 0.0139067 67.677 0.987048 18.8788 0.363338 43.973 0.429372 -1.02653 1.74194 19.3 1 S VPALGKSPPHHSG NEK6;Proline-directed 0.05 0.0139067 67.677 _AVPALGKpSPPHHSGFQQYQQADASK_ AVPALGKS(0.992)PPHHS(0.008)GFQQYQQADASK AVPALGKS(21.18)PPHHS(-21.18)GFQQY(-40.22)QQADAS(-64.02)K 8 3 910.43257 -0.47161 3091900 0 0 0 2940500 0 151310 0 1926 1338 740 740 616 709 5832 3442 Mix4_InSol_Tio2_Reinj_1 5087 5835 3445 Mix4_TiO2_Reinj_1_5 4640 Q92540-4;Q92540;Q92540-2 Q92540-4 Q92540-4 >sp|Q92540-4|SMG7_HUMAN Isoform 4 of Protein SMG7 OS=Homo sapiens GN=SMG7;>sp|Q92540|SMG7_HUMAN Protein SMG7 OS=Homo sapiens GN=SMG7 PE=1 SV=2;>sp|Q92540-2|SMG7_HUMAN Isoform 2 of Protein SMG7 OS=Homo sapiens GN=SMG7 0.543858 1.02653 0.49755 0 1.37188 26.495 0 0 0.123451 -8.5118 0.0139067 67.677 0.012778 -18.8788 0.363338 43.973 0.543858 1.02653 1.74194 19.3 1 S KSPPHHSGFQQYQ 0.0139067 67.677 _AVPALGKSPPHHpSGFQQYQQADASK_ AVPALGKS(0.429)PPHHS(0.544)GFQQY(0.02)QQADAS(0.006)K AVPALGKS(-1.03)PPHHS(1.03)GFQQY(-14.26)QQADAS(-19.3)K 13 3 910.43257 -0.066421 94777 0 0 0 0 0 0 94777 1927 1339 145 145 510 576 4736 2859 Mix4_TiO2_1_4 3704 4739 2863 Mix4_TiO2_Reinj_1_4 4330 Q92551 Q92551 Q92551 >sp|Q92551|IP6K1_HUMAN Inositol hexakisphosphate kinase 1 OS=Homo sapiens GN=IP6K1 PE=1 SV=3 0.421763 0 0.421763 0 0.000505481 92.745 0 0 0.305605 0 3.09468E-17 156.47 1 S SLETSESSQEAKS CK2 0.117 3.09468E-17 156.47 _ASLSLETSEpSSQEAKSPK_ ASLSLET(0.052)S(0.052)ES(0.422)S(0.422)QEAKS(0.052)PK AS(-46.45)LS(-46.45)LET(-9.08)S(-9.08)ES(0)S(0)QEAKS(-9.08)PK 10 3 653.63666 0.41152 0 0 0 0 0 0 0 0 1928 1339 146 146 510 576 4736 2859 Mix4_TiO2_1_4 3704 4739 2863 Mix4_TiO2_Reinj_1_4 4330 Q92551 Q92551 Q92551 >sp|Q92551|IP6K1_HUMAN Inositol hexakisphosphate kinase 1 OS=Homo sapiens GN=IP6K1 PE=1 SV=3 0.421763 0 0.421763 0 0.000505481 92.745 0 0 0.305605 0 3.09468E-17 156.47 1 S LETSESSQEAKSP CK1 0.081 3.09468E-17 156.47 _ASLSLETSEpSSQEAKSPK_ ASLSLET(0.052)S(0.052)ES(0.422)S(0.422)QEAKS(0.052)PK AS(-46.45)LS(-46.45)LET(-9.08)S(-9.08)ES(0)S(0)QEAKS(-9.08)PK 11 3 653.63666 0.41152 0 0 0 0 0 0 0 0 1929 1339 151 151 510 576 4737 2861 Mix4_TiO2_1_4 3727 4739 2863 Mix4_TiO2_Reinj_1_4 4330 Q92551 Q92551 Q92551 >sp|Q92551|IP6K1_HUMAN Inositol hexakisphosphate kinase 1 OS=Homo sapiens GN=IP6K1 PE=1 SV=3 1 66.9568 1 66.9568 0.000505481 92.745 0 0 0.999991 53.5622 3.09468E-17 156.47 1 S SSQEAKSPKVELH CDK1;Proline-directed 0.0057 3.09468E-17 156.47 _ASLSLETSESSQEAKpSPK_ ASLSLETSESSQEAKS(1)PK AS(-92.75)LS(-92.75)LET(-84.91)S(-79.4)ES(-66.96)S(-66.96)QEAKS(66.96)PK 16 2 979.95135 0.35101 292400 81946 0 0 210460 0 0 0 1930 1342 505 505 2210 2502 20263 12444 Mix4_TiO2_1_5 5404 20263 12444 Mix4_TiO2_1_5 5404 Q92574 Q92574 Q92574 >sp|Q92574|TSC1_HUMAN Hamartin OS=Homo sapiens GN=TSC1 PE=1 SV=2 0.999948 42.8246 0.999948 42.8246 0.00531338 67.886 0 0 0.999082 30.3655 0.0235559 55.428 0 0 0 0 1 S PRGGFDSPFYRDS Proline-directed 0.05 0.00531338 67.886 _GGFDpSPFYR_ GGFDS(1)PFYR GGFDS(42.82)PFY(-42.82)R 5 2 563.22369 0.91054 447330 112270 0 0 335060 0 0 0 1931 1343 809 809 2750 3134 26038 16110 Mix4_TiO2_Reinj_1_5 3562 26037 16108 Mix4_TiO2_Reinj_1_3 3488 Q92598;Q92598-3;Q92598-2 Q92598 Q92598 >sp|Q92598|HS105_HUMAN Heat shock protein 105 kDa OS=Homo sapiens GN=HSPH1 PE=1 SV=1;>sp|Q92598-3|HS105_HUMAN Isoform 3 of Heat shock protein 105 kDa OS=Homo sapiens GN=HSPH1;>sp|Q92598-2|HS105_HUMAN Isoform Beta of Heat shock protein 105 kDa OS=Homo sapie 1 21.5616 1 32.461 0.29536 32.461 1 21.5616 0.0866472 50.267 1 11.4191 0.888655 11.419 1 9.72049 0.955774 9.7205 1 S PKPKIESPKLERT CDK1;Proline-directed 0.0057 0.0866472 50.267 _IEpSPKLER_ IES(1)PKLER IES(21.56)PKLER 3 2 526.26281 0.29806 2433000 337940 0 0 1288700 0 409870 396510 1932 1344 233 233 4055 4621 38348 23514 Mix4_InSol_Tio2_Reinj_1 3253 38347 23513 Mix4_InSol_TiO2_1 3246 Q92604 Q92604 Q92604 >sp|Q92604|LGAT1_HUMAN Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 OS=Homo sapiens GN=LPGAT1 PE=2 SV=1 1 94.9215 0 0 1 111.914 2.5453E-05 112.98 1 94.9215 0.000666424 94.922 1 S AQQKNGSPAGGDA Proline-directed 0.05 2.5453E-05 112.98 _NGpSPAGGDAKELDSK_ NGS(1)PAGGDAKELDSK NGS(94.92)PAGGDAKELDS(-94.92)K 3 2 763.33014 0.22563 673320 0 0 0 0 0 394180 279140 1933 1345 1731 1731 3057 3477 29153 18219 Mix4_TiO2_Reinj_1_5 5479 29153 18219 Mix4_TiO2_Reinj_1_5 5479 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.900678 9.57558 0 0 0.900678 9.57558 0.00109786 80.147 1 S RKHEFMSDTNLSE 0.00109786 80.147 _KHEFM(ox)pSDTNLSEHAAIPLK_ KHEFMS(0.901)DT(0.099)NLSEHAAIPLK KHEFMS(9.58)DT(-9.58)NLS(-50.56)EHAAIPLK 6 3 755.35209 0.91178 215210 0 0 0 215210 0 0 0 1934 1345 1784 1784 3732 4209 35209 21784 Mix4_TiO2_Reinj_1_5 6396 35209 21784 Mix4_TiO2_Reinj_1_5 6396 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.999501 33.0177 0.269884 -4.07344 0.414608 12.296 0.999501 33.0177 0.0199625 63.873 1 S NTSPRLSQTFLQL CK1;PKA 0.042 0.0199625 63.873 _LpSQTFLQLSDGDKK_ LS(1)QTFLQLSDGDKK LS(33.02)QT(-33.02)FLQLS(-63.87)DGDKK 2 3 553.93783 -0.70687 622280 0 0 0 622280 0 0 0 1935 1345 1705 1705 5050;5768 5744;6573 56778 34638 Mix4_TiO2_1_5 3467 48821 29840 Mix4_TiO2_Reinj_1_5 4003 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.892807 9.20591 0.892807 9.20591 0.0135079 58.084 0 0 0.399459 -1.7707 0.0133869 58.124 0.228925 -5.27403 0.0395396 49.465 0 0 1 S KKRTKRSSVVFAD 0.0133869 58.124 _pSSVVFADEK_ S(0.893)S(0.107)VVFADEK S(9.21)S(-9.21)VVFADEK 1 2 531.23118 1.9496 189240 189240 0 0 0 0 0 0 1936 1345 1706 1706 5050;5768 5744;6573 48820 29839 Mix4_TiO2_Reinj_1_1 3509 48821 29840 Mix4_TiO2_Reinj_1_5 4003 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.772164 5.30087 0.735815 4.44861 0.0135079 58.084 0 0 0.772164 5.30087 0.0133869 58.124 0.771075 5.27403 0.0395396 49.465 0 0 1 S KRTKRSSVVFADE AURORA;AURORA-1;AURORA-A;CK1;PKA 0.006142092 0.0133869 58.124 _RSpSVVFADEK_ RS(0.228)S(0.772)VVFADEK RS(-5.3)S(5.3)VVFADEK 3 2 609.28174 -0.24408 1444300 157680 0 0 1253900 0 32717 0 1937 1345 1685 1685 6394 7315 64605 39629 Mix4_TiO2_1_5 5153 64605 39629 Mix4_TiO2_1_5 5153 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 1 65.2103 1 65.2103 8.00572E-43 234.15 0.998626 29.3438 6.85463E-06 105.13 0.999988 49.4114 6.00993E-36 233.71 0.999934 42.1152 1.86071E-16 168.91 0.997858 27.4782 7.63881E-06 103.64 1 S EQEEPISPGSTLP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 8.00572E-43 234.15 _VEQEEPIpSPGSTLPEVK_ VEQEEPIS(1)PGSTLPEVK VEQEEPIS(65.21)PGS(-65.21)T(-101.24)LPEVK 8 2 959.9559 0.090174 3007700 118.18 768990 54050 0 1924300 0 147340 113050 1938 1345 1688 1688 6394 7315 64601 39625 Mix4_InSol_TiO2_2 4746 64605 39629 Mix4_TiO2_1_5 5153 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.395317 0 0.00258392 -25.8641 8.00572E-43 234.15 0.00116152 -29.3438 6.85463E-06 105.13 0.0023113 -26.3498 6.00993E-36 233.71 0.395317 0 1.86071E-16 168.91 0.149044 -6.7297 7.63881E-06 103.64 1 S EPISPGSTLPEVK CK1 0.081 8.00572E-43 234.15 _VEQEEPISPGpSTLPEVK_ VEQEEPIS(0.209)PGS(0.395)T(0.395)LPEVK VEQEEPIS(-2.76)PGS(0)T(0)LPEVK 11 2 959.9559 -0.24731 0 0 0 0 0 0 0 0 0 1939 1346 554 554 1524;1525 1713;1714;1715 14071 8579 Mix4_TiO2_Reinj_1_3 3024 14051 8571 Mix4_TiO2_Reinj_1_3 3375 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.906901 11.1116 0.331844 0 0.0768905 45.038 0 0 0.906901 11.1116 0.0137825 66.4 0.00287279 -24.8199 0.15476 37.035 0.583887 2.53629 0.280455 29.2 1 S GREFTGSPPSSAT GSK3;Proline-directed 0.05 0.0137825 66.4 _EFTGpSPPSSATKK_ EFT(0.002)GS(0.907)PPS(0.012)S(0.07)AT(0.009)KK EFT(-26.93)GS(11.11)PPS(-18.65)S(-11.11)AT(-20.2)KK 5 2 708.82396 0.17845 1387300 0 0 0 1037400 0 0 349900 1940 1346 557 557 1524;1525 1713;1714;1715 14067 8575 Mix4_InSol_TiO2_1 3371 14051 8571 Mix4_TiO2_Reinj_1_3 3375 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.871554 8.55487 0.490026 0 0.0768905 45.038 0 0 0.472721 0.971145 0.898893 4.6619 0.871554 8.55487 0.15476 37.035 0.0444252 -11.187 0.280455 29.2 1 S FTGSPPSSATKKD CK1 0.081 0.0137825 66.4 _EFTGSPPpSSATKK_ EFTGS(0.003)PPS(0.872)S(0.122)AT(0.004)KK EFT(-37.04)GS(-24.82)PPS(8.55)S(-8.55)AT(-23.56)KK 8 2 708.82396 0.55507 433510 0 0 0 0 0 433510 0 1941 1346 558 558 1524;1525 1713;1714;1715 14070 8578 Mix4_TiO2_1_5 2518 14051 8571 Mix4_TiO2_Reinj_1_3 3375 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.490026 0 0.490026 0 0.0768905 45.038 0 0 0.405668 -0.971145 0.898893 4.6619 0.121565 -8.55487 0.15476 37.035 0.0444252 -11.187 0.280455 29.2 1 S TGSPPSSATKKDS CK1 0.143 0.0137825 66.4 _EFTGSPPpSSATKK_ EFT(0.004)GS(0.004)PPS(0.49)S(0.49)AT(0.013)KK EFT(-21.46)GS(-21.46)PPS(0)S(0)AT(-15.78)KK 9 2 708.82396 0.55858 0 0 0 0 0 0 0 0 1942 1346 538 538 4085 4653 38662 23705 Mix4_TiO2_1_3 4182 38662 23705 Mix4_TiO2_1_3 4182 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.684281 3.68306 0.684281 3.68306 1.44397E-07 133.53 0 0 0 0 1 S SSKNISSSPSVES 1.44397E-07 133.53 _NISpSSPSVESLPGGR_ NIS(0.001)S(0.684)S(0.293)PS(0.022)VESLPGGR NIS(-27.66)S(3.68)S(-3.68)PS(-15.03)VES(-58.28)LPGGR 4 2 783.86161 0.57412 119370 119370 0 0 0 0 0 0 1943 1346 43 43 5061;6246 5755;7136 48937 29899 Mix4_TiO2_1_3 4430 48940 29902 Mix4_TiO2_Reinj_1_3 5147 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.695885 4.53163 0.695885 4.53163 0.000424469 95.611 0.533339 1.55859 1.03037E-15 158.33 0.195377 -1.78631 0.614703 24.686 0.239218 -4.50726 0.00164998 86.019 1 S KNGRRTSSTLDSE CAMK2;PKA;PKA/AKT 0.00111111 1.03037E-15 158.33 _RTpSSTLDSEGTFNSYR_ RT(0.049)S(0.696)S(0.245)T(0.01)LDSEGTFNSYR RT(-11.55)S(4.53)S(-4.53)T(-18.31)LDS(-57.89)EGT(-67.42)FNS(-95.61)Y(-95.61)R 3 2 950.90728 0.50464 669660 170500 0 0 499160 0 0 0 1944 1346 44 44 5061;6246 5755;7136 48939 29901 Mix4_TiO2_Reinj_1_3 5126 48940 29902 Mix4_TiO2_Reinj_1_3 5147 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.557238 3.54843 0.409779 1.75059 0.000424469 95.611 0.557238 3.54843 1.03037E-15 158.33 0.294784 0 0.614703 24.686 0.0847241 -9.01513 0.00164998 86.019 1 S NGRRTSSTLDSEG CAMK2;CK2;GSK3 0.042 1.03037E-15 158.33 _RTSpSTLDSEGTFNSYR_ RT(0.022)S(0.246)S(0.557)T(0.174)LDSEGTFNSYR RT(-13.95)S(-3.55)S(3.55)T(-5.05)LDS(-41.08)EGT(-51.92)FNS(-87.03)Y(-87.03)R 4 2 950.90728 -0.00016392 723330 0 0 0 723330 0 0 0 1945 1348 601 601 5583 6363 54611 33430 Mix4_TiO2_Reinj_1_3 3876 54611 33430 Mix4_TiO2_Reinj_1_3 3876 Q92615 Q92615 Q92615 >sp|Q92615|LAR4B_HUMAN La-related protein 4B OS=Homo sapiens GN=LARP4B PE=1 SV=3 0.79316 5.83725 0.759851 5.00248 0.0794393 34.921 0.79316 5.83725 0.065069 46.681 1 S TYERSPSPAHLPD CAMK2;Proline-directed 0.042 0.065069 46.681 _SPpSPAHLPDDPK_ S(0.207)PS(0.793)PAHLPDDPK S(-5.84)PS(5.84)PAHLPDDPK 3 2 670.79775 -0.087486 356190 0 0 0 356190 0 0 0 1946 1350 23 23 250 287 2489 1574 Mix4_TiO2_Reinj_1_5 4133 2489 1574 Mix4_TiO2_Reinj_1_5 4133 Q92619 Q92619 Q92619 >sp|Q92619|HMHA1_HUMAN Minor histocompatibility protein HA-1 OS=Homo sapiens GN=HMHA1 PE=1 SV=2 0.999983 47.5775 0.982532 17.5772 0.221695 35.104 0.999983 47.5775 0.00273669 83.632 1 S KKNRAGSPSPQPS CAMK2;Proline-directed 0.042 0.00273669 83.632 _AGpSPSPQPSGELPR_ AGS(1)PSPQPSGELPR AGS(47.58)PS(-47.58)PQPS(-83.63)GELPR 3 2 730.33249 -0.013859 135260 31530 0 0 103730 0 0 0 1947 1351 1942 1942 3645 4110 34320 21314 Mix4_TiO2_Reinj_1_5 7030 34319 21313 Mix4_TiO2_1_5 6174 Q92621 Q92621 Q92621 >sp|Q92621|NU205_HUMAN Nuclear pore complex protein Nup205 OS=Homo sapiens GN=NUP205 PE=1 SV=3 0.985492 18.3342 0.980739 17.2072 1.56943E-11 166.67 0 0 0.985492 18.3342 1.96953E-11 164.31 0 0 0.956992 15.236 0.000294216 98.381 0 0 1 S LQDSFASETNLDF CK1 0.081 1.56943E-11 166.67 _LQDSFApSETNLDFR_ LQDSFAS(0.985)ET(0.014)NLDFR LQDS(-43.37)FAS(18.33)ET(-18.33)NLDFR 7 2 861.87217 0.41907 286670 63236 0 0 187640 0 35791 0 1948 1351 1165 1165 5845 6665 57627 35079 Mix4_TiO2_Reinj_1_5 7296 57627 35079 Mix4_TiO2_Reinj_1_5 7296 Q92621 Q92621 Q92621 >sp|Q92621|NU205_HUMAN Nuclear pore complex protein Nup205 OS=Homo sapiens GN=NUP205 PE=1 SV=3 0.999942 42.3986 0.993708 21.9847 2.17006E-06 149.13 0 0 0.999942 42.3986 6.40155E-09 162.38 0 0 0 0 1 S IEDENRSVSGFLH 6.40155E-09 162.38 _pSVSGFLHFDTATK_ S(1)VSGFLHFDTATK S(42.4)VS(-42.4)GFLHFDT(-162.38)AT(-162.38)K 1 2 745.33978 -0.042362 1781500 329280 0 0 1452200 0 0 0 1949 1351 1167 1167 5845 6665 57628 35080 Mix4_TiO2_Reinj_1_5 7484 57627 35079 Mix4_TiO2_Reinj_1_5 7296 Q92621 Q92621 Q92621 >sp|Q92621|NU205_HUMAN Nuclear pore complex protein Nup205 OS=Homo sapiens GN=NUP205 PE=1 SV=3 0.499994 0 0.400031 -1.76036 2.17006E-06 149.13 0 0 0.499994 0 6.40155E-09 162.38 0 0 0 0 1 S DENRSVSGFLHFD CAMK2 0.042 6.40155E-09 162.38 _pSVSGFLHFDTATK_ S(0.5)VS(0.5)GFLHFDTATK S(0)VS(0)GFLHFDT(-49.55)AT(-49.55)K 3 2 745.33978 0.29275 130180 0 0 0 130180 0 0 0 1950 1352 30 30 4631 5257 43892 26916 Mix4_InSol_Tio2_Reinj_1 4493 43895 26919 Mix4_TiO2_Reinj_1_3 4256 Q92630 Q92630 Q92630 >sp|Q92630|DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2 PE=1 SV=3 1 65.3826 0.999994 52.4496 0.00429408 78.688 0.999999 59.7738 0.000221433 99.071 0.999991 50.3501 0.0149728 68.575 1 65.3826 0.00214685 87.194 1 S VRQLQASPGLGAG NEK6;Proline-directed 0.05 0.000221433 99.071 _QLQApSPGLGAGATR_ QLQAS(1)PGLGAGATR QLQAS(65.38)PGLGAGAT(-65.38)R 5 2 703.84302 -0.28297 1730800 357230 0 0 902120 0 217160 254330 1951 1352 48 48 5341 6082 51869 31751 Mix4_TiO2_Reinj_1_3 7240 51867 31748 Mix4_TiO2_1_3 6457 Q92630 Q92630 Q92630 >sp|Q92630|DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2 PE=1 SV=3 0.496669 0 0.345118 -2.78065 4.12467E-06 110.28 0.0162349 -17.7742 0.0821277 51.856 0.496669 0 0.000535578 93.769 1 S VGTGPPSPIALPP CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.12467E-06 110.28 _SGVGpTGPPSPIALPPLR_ S(0.007)GVGT(0.497)GPPS(0.497)PIALPPLR S(-18.73)GVGT(0)GPPS(0)PIALPPLR 9 2 848.44511 0.21294 0 0 0 0 0 0 0 0 1952 1353 429 429 6286 7182 62913 38320 Mix4_TiO2_Reinj_1_5 7925 62913 38320 Mix4_TiO2_Reinj_1_5 7925 Q92667;Q92667-2 Q92667 Q92667 >sp|Q92667|AKAP1_HUMAN A-kinase anchor protein 1, mitochondrial OS=Homo sapiens GN=AKAP1 PE=1 SV=1;>sp|Q92667-2|AKAP1_HUMAN Isoform S-AKAP84 of A-kinase anchor protein 1, mitochondrial OS=Homo sapiens GN=AKAP1 1 98.4165 1 68.5952 0.07676 75.632 0.999578 36.5917 1.59392 43.144 1 98.4165 1.98558E-06 101.48 1 S GLPAEGSPPPKTY Proline-directed 0.05 1.98558E-06 101.48 _TVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGpSPPPK_ TVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGS(1)PPPK T(-98.42)VLGPDT(-99.13)AEPAT(-99.15)AEAAVAPPDAGLPLPGLPAEGS(98.42)PPPK 34 4 913.7103 0.21837 2296000 594760 86226 0 1615000 0 0 0 1953 1355 11 11 2420;5322 2743;6058 51641 31612 Mix4_InSol_TiO2_2 2367 51650 31625 Mix4_TiO2_Reinj_1_2 2682 Q92685 Q92685 Q92685 >sp|Q92685|ALG3_HUMAN Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase OS=Homo sapiens GN=ALG3 PE=1 SV=1 0.958245 13.6077 0.5 0 8.18606E-05 125.76 0 0 0.5 0 6.9514E-05 127.88 0 0 0.958245 13.6077 1.33119E-06 123.49 0.5 0 0.000208572 116.54 1 S LRKRGRSGSAAQA CAMK2;PKA;PKA/AKT 0.001764 6.9514E-05 127.88 _pSGSAAQAEGLCK_ S(0.958)GS(0.042)AAQAEGLCK S(13.61)GS(-13.61)AAQAEGLCK 1 2 629.76031 0.42984 2996200 362590 0 0 1903400 0 12111 718170 1954 1355 13 13 2420;5322 2743;6058 51640 31610 Mix4_InSol_TiO2_1 3323 51650 31625 Mix4_TiO2_Reinj_1_2 2682 Q92685 Q92685 Q92685 >sp|Q92685|ALG3_HUMAN Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase OS=Homo sapiens GN=ALG3 PE=1 SV=1 0.917201 10.4444 0.883352 8.79258 8.18606E-05 125.76 0 0 0.5 0 6.9514E-05 127.88 0 0 0.917201 10.4444 1.33119E-06 123.49 0.799014 5.99389 0.000208572 116.54 1 S KRGRSGSAAQAEG CAMK2;PKA/AKT 0.001764 6.9514E-05 127.88 _SGpSAAQAEGLCK_ S(0.083)GS(0.917)AAQAEGLCK S(-10.44)GS(10.44)AAQAEGLCK 3 2 629.76031 0.146 4037700 463460 0 0 1903400 0 789460 881410 1955 1357 422 422 2687 3060 25262 15594 Mix4_TiO2_1_4 3447 25262 15594 Mix4_TiO2_1_4 3447 Q92769 Q92769 Q92769 >sp|Q92769|HDAC2_HUMAN Histone deacetylase 2 OS=Homo sapiens GN=HDAC2 PE=1 SV=2 1 65.1421 1 65.1421 0.0155599 65.142 2 S ACDEEFSDSEDEG CK2 0.117 0.0155599 65.142 _IACDEEFpSDpSEDEGEGGRR_ IACDEEFS(1)DS(1)EDEGEGGRR IACDEEFS(65.14)DS(65.14)EDEGEGGRR 8 2 1159.4012 -0.7878 38119 38119 0 0 0 0 0 0 1956 1357 424 424 2687 3060 25262 15594 Mix4_TiO2_1_4 3447 25262 15594 Mix4_TiO2_1_4 3447 Q92769 Q92769 Q92769 >sp|Q92769|HDAC2_HUMAN Histone deacetylase 2 OS=Homo sapiens GN=HDAC2 PE=1 SV=2 1 65.1421 1 65.1421 0.0155599 65.142 2 S DEEFSDSEDEGEG CK2 0.117 0.0155599 65.142 _IACDEEFpSDpSEDEGEGGRR_ IACDEEFS(1)DS(1)EDEGEGGRR IACDEEFS(65.14)DS(65.14)EDEGEGGRR 10 2 1159.4012 -0.7878 38119 38119 0 0 0 0 0 0 1957 1358 1173 1173 3507 3960 33104 20470 Mix4_TiO2_Reinj_1_5 3570 33104 20470 Mix4_TiO2_Reinj_1_5 3570 Q92797 Q92797 Q92797 >sp|Q92797|SYMPK_HUMAN Symplekin OS=Homo sapiens GN=SYMPK PE=1 SV=2 0.996081 25.6567 0.957894 14.3717 4.34757E-11 126.73 0.996081 25.6567 1.23181E-23 160.13 1 S PSSSSPSPSPSAR CK1;GSK3;Proline-directed 0.05 1.23181E-23 160.13 _LKPGGVGAPSSSSPpSPSPSAR_ LKPGGVGAPSSS(0.001)S(0.003)PS(0.996)PSPSAR LKPGGVGAPS(-41.34)S(-40.05)S(-32.21)S(-25.66)PS(25.66)PS(-33.55)PS(-64.17)AR 15 2 1001.9833 0.029825 1216900 290690 0 0 926220 0 0 0 1958 1358 1259 1259 6155 7027 60957 36931 Mix4_TiO2_Reinj_1_5 2950 60957 36931 Mix4_TiO2_Reinj_1_5 2950 Q92797 Q92797 Q92797 >sp|Q92797|SYMPK_HUMAN Symplekin OS=Homo sapiens GN=SYMPK PE=1 SV=2 0.996086 24.0571 0.866852 8.13612 0.111421 38.982 0.996086 24.0571 0.134215 40.864 1 S DAMKTPSPAAEDA Proline-directed 0.05 0.134215 40.864 _TPpSPAAEDAREPEAK_ T(0.004)PS(0.996)PAAEDAREPEAK T(-24.06)PS(24.06)PAAEDAREPEAK 3 3 550.24532 -0.70552 410480 0 0 0 410480 0 0 0 1959 1359 228 228 5927 6760 58424 35438 Mix4_TiO2_Reinj_1_3 8930 58424 35438 Mix4_TiO2_Reinj_1_3 8930 Q92804;Q92804-2 Q92804 Q92804 >sp|Q92804|RBP56_HUMAN TATA-binding protein-associated factor 2N OS=Homo sapiens GN=TAF15 PE=1 SV=1;>sp|Q92804-2|RBP56_HUMAN Isoform Short of TATA-binding protein-associated factor 2N OS=Homo sapiens GN=TAF15 0.301361 0.659377 0.301361 0.659377 0.000428535 82.528 1 S TDADSESDNSDNN 0.000428535 82.528 _TDADSEpSDNSDNNTIFVQGLGEGVSTDQVGEFFK_ T(0.259)DADS(0.259)ES(0.301)DNS(0.09)DNNT(0.09)IFVQGLGEGVSTDQVGEFFK T(-0.66)DADS(-0.66)ES(0.66)DNS(-5.23)DNNT(-5.23)IFVQGLGEGVS(-68.54)T(-67.08)DQVGEFFK 7 3 1234.8583 -0.22422 0 0 0 0 0 0 0 0 0 1960 1361 357 357 25 33 282 159 Mix4_TiO2_Reinj_1_4 8979 282 159 Mix4_TiO2_Reinj_1_4 8979 Q92844 Q92844 Q92844 >sp|Q92844|TANK_HUMAN TRAF family member-associated NF-kappa-B activator OS=Homo sapiens GN=TANK PE=1 SV=2 0.953119 13.0824 0.946842 12.5157 0.0578888 70.89 0.953119 13.0824 1.13904E-12 133.66 1 S PFPSLDSPGKAIR CDK1;CDK2;CK1;Proline-directed 0.0057 1.13904E-12 133.66 _AACLPPGDHNALYVNSFPLLDPSDAPFPSLDpSPGK_ AACLPPGDHNALYVNSFPLLDPSDAPFPS(0.047)LDS(0.953)PGK AACLPPGDHNALY(-115.99)VNS(-109.32)FPLLDPS(-50.4)DAPFPS(-13.08)LDS(13.08)PGK 32 3 1253.9182 0.13096 2139100 102940 0 0 2036100 0 0 0 1961 1361 225 225 2300 2602 21287 13048 Mix4_InSol_TiO2_1 5660 21289 13050 Mix4_InSol_Tio2_Reinj_1 5581 Q92844 Q92844 Q92844 >sp|Q92844|TANK_HUMAN TRAF family member-associated NF-kappa-B activator OS=Homo sapiens GN=TANK PE=1 SV=2 0.965855 15.2315 0.922379 10.9516 0.00200375 83.25 0.38337 -2.06401 0.00206459 82.773 0.965855 15.2315 5.48078E-06 110.43 0.767872 5.19786 4.44392E-06 111.88 1 S RDEEDTSFESLSK PLK1 0.033462 4.44392E-06 111.88 _GLCRDEEDTpSFESLSK_ GLCRDEEDT(0.029)S(0.966)FES(0.005)LSK GLCRDEEDT(-15.23)S(15.23)FES(-22.7)LS(-88.17)K 10 2 976.9008 -0.20978 549180 63020 0 0 0 0 371960 114200 1962 1361 129 129 5439 6190 53061 32441 Mix4_TiO2_Reinj_1_4 5779 53061 32441 Mix4_TiO2_Reinj_1_4 5779 Q92844 Q92844 Q92844 >sp|Q92844|TANK_HUMAN TRAF family member-associated NF-kappa-B activator OS=Homo sapiens GN=TANK PE=1 SV=2 1 67.3968 0.999503 33.0336 0.000864359 81.535 0 0 1 67.3968 0.00478723 119.88 0.998008 26.9977 0.00596444 63.462 0.99977 36.39 0.0787218 39.835 1 S SARSLGSPLLHER CK1;Proline-directed 0.05 0.00478723 119.88 _SLGpSPLLHER_ SLGS(1)PLLHER S(-67.4)LGS(67.4)PLLHER 4 2 594.79227 0.02313 3327900 460550 0 0 1427300 0 805420 634710 1963 1364 310 310 3993 4549 37803 23198 Mix4_TiO2_Reinj_1_5 2273 37802 23197 Mix4_TiO2_Reinj_1_5 2271 Q92922 Q92922 Q92922 >sp|Q92922|SMRC1_HUMAN SWI/SNF complex subunit SMARCC1 OS=Homo sapiens GN=SMARCC1 PE=1 SV=3 1 0.184992 1 0.184992 0.0742632 41.439 1 S NEEPVRSPERRDR CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 0.0742632 41.439 _NEEPVRpSPERR_ NEEPVRS(1)PERR NEEPVRS(0.18)PERR 7 2 724.83573 -0.12275 262560 0 0 0 262560 0 0 0 1964 1365 480 480 2456;3419 2786;3862 32135 19863 Mix4_InSol_Tio2_Reinj_1 6472 32132 19859 Mix4_InSol_TiO2_1 6466 Q92945;Q92945-2 Q92945 Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP PE=1 SV=3;>sp|Q92945-2|FUBP2_HUMAN Isoform 2 of Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP 1 6.899 0 0 1 35.8934 0.126296 35.893 1 17.9731 0.151602 40.184 1 6.899 0.22186 37.339 1 S LFIIRGSPQQIDH PKA;Proline-directed 0.042 0.151602 40.184 _LFIIRGpSPQQIDHAK_ LFIIRGS(1)PQQIDHAK LFIIRGS(6.9)PQQIDHAK 7 2 901.96929 0.085802 1704500 8.4575 0 0 0 1123900 0 230370 350250 1965 1365 99 99 2765;2766 3153;3155 26410 16525 Mix4_TiO2_Reinj_1_3 6339 26408 16523 Mix4_TiO2_1_3 5542 Q92945;Q92945-2 Q92945 Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP PE=1 SV=3;>sp|Q92945-2|FUBP2_HUMAN Isoform 2 of Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP 0.668375 3.04373 0.174585 -6.74666 3.18618E-24 168.76 0 0 0.668375 3.04373 1.20455E-07 115.74 0.0901449 -10.0351 6.5829E-07 105.17 0.474217 0 0.000430572 85.948 1 S ATTVNNSTPDFGF CK1;CK2 0.117 3.18618E-24 168.76 _IGGDAATTVNNpSTPDFGFGGQK_ IGGDAATTVNNS(0.668)T(0.332)PDFGFGGQK IGGDAAT(-73.34)T(-66.25)VNNS(3.04)T(-3.04)PDFGFGGQK 12 2 1117.4917 1.6133 530370 0.18692 0 0 0 530370 0 0 0 1966 1365 2 2 5194 5913 50366 30885 Mix4_TiO2_1_3 4615 50366 30885 Mix4_TiO2_1_3 4615 Q92945;Q92945-2 Q92945 Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP PE=1 SV=3;>sp|Q92945-2|FUBP2_HUMAN Isoform 2 of Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP 0.906613 11.5396 0.906613 11.5396 0.00283467 85.72 1 S _____MSDYSTGG 0.00283467 85.72 _(ac)pSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDR_ S(0.907)DY(0.013)S(0.064)T(0.017)GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDR S(11.54)DY(-18.35)S(-11.54)T(-17.39)GGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDR 1 3 1109.4881 -1.11 196220 0.00072722 196220 0 0 0 0 0 0 1967 1365 181 181 6564 7510 66442 40780 Mix4_InSol_TiO2_1 5109 66451 40796 Mix4_TiO2_Reinj_1_3 4897 Q92945;Q92945-2 Q92945 Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP PE=1 SV=3;>sp|Q92945-2|FUBP2_HUMAN Isoform 2 of Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP 0.998896 29.5636 0.968986 14.9476 4.40879E-05 121.07 0 0 0.00647523 -21.8592 7.63056E-06 136.49 0 0 0.998896 29.5636 0.000112022 115.99 0.996244 24.236 0.000330474 108.51 1 S GCKVQISPDSGGL Proline-directed 0.05 7.63056E-06 136.49 _VQIpSPDSGGLPER_ VQIS(0.999)PDS(0.001)GGLPER VQIS(29.56)PDS(-29.56)GGLPER 4 2 717.83486 0.031797 4220900 10.439 1495300 0 0 0 0 1515200 1210500 1968 1365 184 184 6564 7510 66451 40796 Mix4_TiO2_Reinj_1_3 4897 66451 40796 Mix4_TiO2_Reinj_1_3 4897 Q92945;Q92945-2 Q92945 Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP PE=1 SV=3;>sp|Q92945-2|FUBP2_HUMAN Isoform 2 of Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP 0.993525 21.8592 0.0663234 -11.4853 4.40879E-05 121.07 0 0 0.993525 21.8592 7.63056E-06 136.49 0 0 0.321454 -3.24461 0.000112022 115.99 0.985252 18.2481 0.000330474 108.51 1 S VQISPDSGGLPER CK1 0.081 7.63056E-06 136.49 _VQISPDpSGGLPER_ VQIS(0.006)PDS(0.994)GGLPER VQIS(-21.86)PDS(21.86)GGLPER 7 2 717.83486 0.061961 5080300 12.564 0 0 0 4966000 0 0 114330 1969 1367 932 932 4522 5136 42825 26309 Mix4_TiO2_Reinj_1_5 2994 42823 26306 Mix4_TiO2_1_5 2282 Q92974;Q92974-2;Q92974-3 Q92974 Q92974 >sp|Q92974|ARHG2_HUMAN Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2 PE=1 SV=4;>sp|Q92974-2|ARHG2_HUMAN Isoform 2 of Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2;>sp|Q92974-3|ARHG2_HUMAN Isoform 3 of Rho guanine 1 87.3725 1 99.931 0.00246237 99.931 1 87.3725 0.00133942 87.373 0 0 0 0 1 S ERQELGSPEERLQ CK2;Proline-directed 0.05 0.00246237 99.931 _QELGpSPEER_ QELGS(1)PEER QELGS(87.37)PEER 5 2 562.73462 0.39756 563700 77959 0 0 485740 0 0 0 1970 1367 886 886 5456 6208 53198 32522 Mix4_TiO2_Reinj_1_5 8101 53197 32521 Mix4_TiO2_Reinj_1_5 8088 Q92974;Q92974-2;Q92974-3 Q92974 Q92974 >sp|Q92974|ARHG2_HUMAN Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2 PE=1 SV=4;>sp|Q92974-2|ARHG2_HUMAN Isoform 2 of Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2;>sp|Q92974-3|ARHG2_HUMAN Isoform 3 of Rho guanine 1 80.3703 1 65.5247 0.000756406 85.979 1 80.3703 1.53825E-15 142.24 1 S VDPRRRSLPAGDA AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.004788 1.53825E-15 142.24 _pSLPAGDALYLSFNPPQPSR_ S(1)LPAGDALYLSFNPPQPSR S(80.37)LPAGDALY(-80.37)LS(-82.18)FNPPQPS(-109.72)R 1 2 1055.5039 0.51029 347640 65893 0 0 281750 0 0 0 1971 1368 2556 2556 423;424 483;485 4013 2392 Mix4_InSol_Tio2_Reinj_1 4007 3972 2363 Mix4_InSol_Tio2_Reinj_1 4056 Q93008-2;Q93008 Q93008-2 Q93008-2 >sp|Q93008-2|USP9X_HUMAN Isoform Long of Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens GN=USP9X;>sp|Q93008|USP9X_HUMAN Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens GN=USP9X PE=1 SV=2 0.999974 47.5143 0.998923 29.6714 3.41234E-20 179.58 0.31021 -3.45626 0.563358 27.816 0.999299 31.5408 1.72043E-16 169.42 0 0 0.997849 26.6681 1.53173E-15 142.3 0.999974 47.5143 1.06641E-20 190.32 1 S EGSEEVSPPQTKD CK1;Proline-directed 0.05 1.06641E-20 190.32 _AQENYEGSEEVpSPPQTKDQ_ AQENYEGSEEVS(1)PPQTKDQ AQENY(-78.01)EGS(-47.51)EEVS(47.51)PPQT(-50.76)KDQ 12 2 1108.455 0.42307 972560 0.34339 232460 0 0 79275 0 262810 398020 1972 1368 1593 1593 4042 4605;4607 38203 23447 Mix4_TiO2_Reinj_1_1 5502 38203 23447 Mix4_TiO2_Reinj_1_1 5502 Q93008-2;Q93008 Q93008-2 Q93008-2 >sp|Q93008-2|USP9X_HUMAN Isoform Long of Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens GN=USP9X;>sp|Q93008|USP9X_HUMAN Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens GN=USP9X PE=1 SV=2 0.999812 37.2683 0.983818 17.9882 0.000284209 85.216 0 0 0.999812 37.2683 5.10856E-48 205.81 0 0 0 0 1 S DVDDDMSGDEKQD CK2 0.117 5.10856E-48 205.81 _NGILAIEGTGSDVDDDM(ox)pSGDEKQDNESNVDPR_ NGILAIEGTGSDVDDDMS(1)GDEKQDNESNVDPR NGILAIEGT(-100.43)GS(-69.23)DVDDDMS(37.27)GDEKQDNES(-37.27)NVDPR 18 3 1163.4808 0.26943 4396800 0.85155 1108100 0 0 3288600 0 0 0 1973 1370 635 635 2136;2137 2420;2421 19655 12006 Mix4_TiO2_Reinj_1_5 6717 19649 11996 Mix4_TiO2_1_1 5547 Q93074-2;Q93074;Q93074-3 Q93074-2 Q93074-2 >sp|Q93074-2|MED12_HUMAN Isoform 2 of Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens GN=MED12;>sp|Q93074|MED12_HUMAN Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens GN=MED12 PE=1 SV=4;>sp|Q93074-3|MED12_HUMAN 1 88.7469 1 18.2694 1.61564E-12 134.98 1 55.4369 0.147256 55.437 1 88.7469 5.14392E-12 129.7 0 0 0 0 1 S PGPRPPSPFDDPA CAMK2;CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.61564E-12 134.98 _GDLAFGAPGPRPPpSPFDDPADDPEHK_ GDLAFGAPGPRPPS(1)PFDDPADDPEHK GDLAFGAPGPRPPS(88.75)PFDDPADDPEHK 14 3 928.07634 0.54857 6702600 1370700 96221 0 5235700 0 0 0 1974 1370 1258 1258 2437 2763 22906 14329 Mix4_TiO2_Reinj_1_1 5051 22906 14329 Mix4_TiO2_Reinj_1_1 5051 Q93074-2;Q93074;Q93074-3 Q93074-2 Q93074-2 >sp|Q93074-2|MED12_HUMAN Isoform 2 of Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens GN=MED12;>sp|Q93074|MED12_HUMAN Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens GN=MED12 PE=1 SV=4;>sp|Q93074-3|MED12_HUMAN 0.999997 54.8237 0 0 0.999997 54.8237 1.06728E-07 112.93 0 0 0 0 1 S EEGGGGSGGRRQG 1.06728E-07 112.93 _GSGFTVTGGTEELPEEEGGGGpSGGRR_ GSGFTVTGGTEELPEEEGGGGS(1)GGRR GS(-112.93)GFT(-112.93)VT(-92.47)GGT(-54.82)EELPEEEGGGGS(54.82)GGRR 22 3 854.03643 0.1642 393270 0 0 0 393270 0 0 0 1975 1370 700 700 2458 2788 23094 14421 Mix4_TiO2_Reinj_1_1 2295 23094 14421 Mix4_TiO2_Reinj_1_1 2295 Q93074-2;Q93074;Q93074-3 Q93074-2 Q93074-2 >sp|Q93074-2|MED12_HUMAN Isoform 2 of Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens GN=MED12;>sp|Q93074|MED12_HUMAN Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens GN=MED12 PE=1 SV=4;>sp|Q93074-3|MED12_HUMAN 0.94759 12.5721 0.894535 9.28487 0.25026 27.591 0 0 0.94759 12.5721 0.0311927 56.272 1 S EGKGSPSPEKPDV CDK1;CDK2;Proline-directed 0.0057 0.0311927 56.272 _GSPpSPEKPDVEK_ GS(0.052)PS(0.948)PEKPDVEK GS(-12.57)PS(12.57)PEKPDVEK 4 2 675.30286 -0.1034 152650 38073 0 0 114580 0 0 0 1976 1371 4 4 101 117 1044 664 Mix4_InSol_Tio2_Reinj_1 7819 1044 664 Mix4_InSol_Tio2_Reinj_1 7819 Q93100-2;Q93100-4 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB 1 73.8752 0 0 1 72.25 0.0110948 72.25 0.99999 54.6022 0.0619991 54.602 1 73.8752 0.00919637 73.875 1 S ___MACSPDAVVS Proline-directed 0.05 0.00919637 73.875 _(ac)ACpSPDAVVSPSSAFLR_ ACS(1)PDAVVSPSSAFLR ACS(73.88)PDAVVS(-73.88)PS(-73.88)S(-73.88)AFLR 3 2 893.3975 -0.008611 1032900 0 0 0 696230 0 153550 183080 1977 1371 693 693 4746;5015 5392;5703;5704 48456 29650 Mix4_TiO2_1_6 5325 48455 29649 Mix4_TiO2_1_5 6313 Q93100-2;Q93100-4;Q93100;Q93100-3 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100|KPBB_HUMAN Phosphorylase b ki 0.813734 5.60127 0.813734 5.60127 3.33371E-11 119.74 0 0 0.542607 0 9.69174E-07 99.063 0.311751 0 0.0173895 60.584 0.441308 0 0.0140872 64.313 2 S SKVKRQSSTPSAP GSK3;PKA 0.042 3.33371E-11 119.74 _RQpSSpTPSAPELGQQPDVNISEWK_ RQS(0.814)S(0.33)T(0.835)PS(0.019)APELGQQPDVNIS(0.002)EWK RQS(5.6)S(-5.6)T(6.52)PS(-16.66)APELGQQPDVNIS(-30.66)EWK 3 3 905.40014 0.45301 271540 212200 0 0 59337 0 0 0 1978 1371 694 694 4746;5015 5392;5703;5704 48457 29651 Mix4_TiO2_Reinj_1_5 7000 48455 29649 Mix4_TiO2_1_5 6313 Q93100-2;Q93100-4;Q93100;Q93100-3 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100|KPBB_HUMAN Phosphorylase b ki 0.591962 1.01155 0.462656 0 1.20866E-17 151.47 0 0 0.591962 1.01155 9.69174E-07 99.063 0.311751 0 0.0173895 60.584 0.441308 0 0.0140872 64.313 2 S KVKRQSSTPSAPE CAMK2;CHK1;PKA;PKD 0.003024 3.33371E-11 119.74 _RQSpSpTPSAPELGQQPDVNISEWK_ RQS(0.487)S(0.592)T(0.904)PS(0.017)APELGQQPDVNISEWK RQS(-1.01)S(1.01)T(7.96)PS(-18.15)APELGQQPDVNIS(-99.06)EWK 4 3 905.40014 0.36196 948990 0 0 0 948990 0 0 0 1979 1371 697 697 4746;5015 5392;5703;5704 48450 29646 Mix4_TiO2_Reinj_1_3 6889 48449 29644 Mix4_TiO2_1_5 6016 Q93100-2;Q93100-4;Q93100;Q93100-3 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100|KPBB_HUMAN Phosphorylase b ki 0.554909 2.30473 0.0725288 -6.29618 1.20866E-17 151.47 0 0 0.554909 2.30473 1.19067E-11 131.09 0.325441 0 0.0173895 60.584 0.0109488 -16.0537 0.0140872 64.313 1 S RQSSTPSAPELGQ CK1;CK2 0.081 1.20866E-17 151.47 _RQSSTPpSAPELGQQPDVNISEWK_ RQS(0.067)S(0.051)T(0.326)PS(0.555)APELGQQPDVNISEWK RQS(-9.16)S(-10.34)T(-2.3)PS(2.3)APELGQQPDVNIS(-100.9)EWK 7 3 878.7447 0.39438 381020 0 0 0 381020 0 0 0 1980 1371 18 18 5334 6075 51810 31722 Mix4_InSol_TiO2_1 5129 51812 31724 Mix4_TiO2_1_5 3932 Q93100-2;Q93100-4;Q93100;Q93100-3 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100|KPBB_HUMAN Phosphorylase b ki 0.498336 0 0.0938291 -9.84867 0.0449057 48.667 0.149586 -6.70719 0.214577 30.587 0.498336 0 0.338431 21.753 0.0938291 -9.84867 0.0449058 48.667 1 S SSAFLRSGSVYEP 0.0449057 48.667 _pSGSVYEPLK_ S(0.498)GS(0.498)VY(0.003)EPLK S(0)GS(0)VY(-21.75)EPLK 1 2 530.24155 0.14467 0 0 0 0 0 0 0 0 1981 1371 20 20 5334 6075 51814 31727 Mix4_TiO2_Reinj_1_5 4873 51812 31724 Mix4_TiO2_1_5 3932 Q93100-2;Q93100-4;Q93100;Q93100-3 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100|KPBB_HUMAN Phosphorylase b ki 0.91294 10.2462 0.906159 9.84867 0.0449057 48.667 0.91294 10.2462 0.214577 30.587 0.498336 0 0.338431 21.753 0.906159 9.84867 0.0449058 48.667 1 S AFLRSGSVYEPLK CAMK2;CK2 0.002856 0.0449057 48.667 _SGpSVYEPLK_ S(0.086)GS(0.913)VY(0.001)EPLK S(-10.25)GS(10.25)VY(-30.59)EPLK 3 2 530.24155 0.11707 519950 69306 0 0 388060 0 0 62579 1982 1379 404 404 5064 5758 48974 29911 Mix4_TiO2_1_4 5760 48973 29910 Mix4_InSol_TiO2_1 6972 Q96AD5;Q96AD5-2 Q96AD5 Q96AD5 >sp|Q96AD5|PLPL2_HUMAN Patatin-like phospholipase domain-containing protein 2 OS=Homo sapiens GN=PNPLA2 PE=1 SV=1;>sp|Q96AD5-2|PLPL2_HUMAN Isoform 2 of Patatin-like phospholipase domain-containing protein 2 OS=Homo sapiens GN=PNPLA2 0.978533 16.5892 0.978533 16.5892 0.0577565 55.278 0.345185 -2.7645 0.54043 27.295 0.964697 14.3664 0.0523742 56.105 0 0 1 S ELRRVQSLPSVPL CAMK2;CHK1;CHK1/2;PKD 0.003192 0.0523742 56.105 _RVQpSLPSVPLSCAAYR_ RVQS(0.979)LPS(0.021)VPLSCAAYR RVQS(16.59)LPS(-16.59)VPLS(-55.28)CAAY(-55.28)R 4 3 628.64477 0.19106 59767 28657 0 0 0 0 31110 0 1983 1379 407 407 5064 5758 48975 29912 Mix4_TiO2_Reinj_1_4 6442 48973 29910 Mix4_InSol_TiO2_1 6972 Q96AD5;Q96AD5-2 Q96AD5 Q96AD5 >sp|Q96AD5|PLPL2_HUMAN Patatin-like phospholipase domain-containing protein 2 OS=Homo sapiens GN=PNPLA2 PE=1 SV=1;>sp|Q96AD5-2|PLPL2_HUMAN Isoform 2 of Patatin-like phospholipase domain-containing protein 2 OS=Homo sapiens GN=PNPLA2 0.652382 2.7645 0.0214614 -16.5892 0.0577565 55.278 0.652382 2.7645 0.54043 27.295 0.0352982 -14.3664 0.0523742 56.105 0 0 1 S RVQSLPSVPLSCA CK1;GSK3 0.081 0.0523742 56.105 _RVQSLPpSVPLSCAAYR_ RVQS(0.345)LPS(0.652)VPLS(0.001)CAAY(0.001)R RVQS(-2.76)LPS(2.76)VPLS(-27.29)CAAY(-27.29)R 7 3 628.64477 0.06807 111640 0 0 0 111640 0 0 0 1984 1380 140 140 2879 3281 27569 17193 Mix4_TiO2_1_3 4634 27569 17193 Mix4_TiO2_1_3 4634 Q96AE4;Q96AE4-2 Q96AE4 Q96AE4 >sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 PE=1 SV=3;>sp|Q96AE4-2|FUBP1_HUMAN Isoform 2 of Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 1 67.8409 1 67.8409 0.0145609 67.841 1 40.895 0.092843 40.895 1 31.6895 0.240523 31.689 1 S IQIAPDSGGLPER 0.0145609 67.841 _IQIAPDpSGGLPER_ IQIAPDS(1)GGLPER IQIAPDS(67.84)GGLPER 7 2 716.84523 -0.41474 160960 0.3991 42767 0 0 0 0 55984 62209 1985 1380 630 630 4684 5316;5317 44502 27296 Mix4_InSol_TiO2_1 4426 44527 27313 Mix4_InSol_TiO2_1 5193 Q96AE4 Q96AE4 Q96AE4 >sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 PE=1 SV=3 0.965118 14.4254 0.888936 9.03295 9.14443E-18 145.46 0.846734 7.42301 6.70951E-12 132.32 0.965118 14.4254 4.88931E-18 150.68 0.965013 14.4086 1.80836E-07 113.89 1 S AYYAQTSPQGMPQ Proline-directed 0.05 4.88931E-18 150.68 _QQAAYYAQTpSPQGM(ox)PQHPPAPQGQ_ QQAAYYAQT(0.035)S(0.965)PQGMPQHPPAPQGQ QQAAY(-63.17)Y(-43.33)AQT(-14.43)S(14.43)PQGMPQHPPAPQGQ 10 3 893.05488 -0.31396 24677000 0.3784 1821900 0 0 376340 0 12974000 9505000 1986 1381 34 34 5276 6004 51209 31381 Mix4_TiO2_1_4 7062 51210 31382 Mix4_TiO2_Reinj_1_4 7471 Q96AG3 Q96AG3 Q96AG3 >sp|Q96AG3|S2546_HUMAN Solute carrier family 25 member 46 OS=Homo sapiens GN=SLC25A46 PE=1 SV=1 0.25952 0 0.25952 0 4.91125E-11 120.79 0.137403 -7.13755 6.87413E-12 135.07 1 S FPARSFSTGSDLG CAMK2 0.042 6.87413E-12 135.07 _SFpSTGSDLGHWVTTPPDIPGSR_ S(0.221)FS(0.26)T(0.26)GS(0.26)DLGHWVT(0.001)TPPDIPGSR S(-0.7)FS(0)T(0)GS(0)DLGHWVT(-26.69)T(-46.12)PPDIPGS(-46.12)R 3 3 798.69691 -0.096364 0 0 0 0 0 0 0 0 1987 1381 37 37 5276 6004 51211 31383 Mix4_TiO2_Reinj_1_4 7734 51210 31382 Mix4_TiO2_Reinj_1_4 7471 Q96AG3 Q96AG3 Q96AG3 >sp|Q96AG3|S2546_HUMAN Solute carrier family 25 member 46 OS=Homo sapiens GN=SLC25A46 PE=1 SV=1 0.710805 7.13755 0.25952 0 4.91125E-11 120.79 0.710805 7.13755 6.87413E-12 135.07 1 S RSFSTGSDLGHWV CK1 0.081 6.87413E-12 135.07 _SFSTGpSDLGHWVTTPPDIPGSR_ S(0.012)FS(0.137)T(0.137)GS(0.711)DLGHWVT(0.002)TPPDIPGSR S(-17.73)FS(-7.14)T(-7.14)GS(7.14)DLGHWVT(-24.73)T(-50.08)PPDIPGS(-65.52)R 6 3 798.69691 -0.23136 237710 0 0 0 237710 0 0 0 1988 1384 2398 2398 1316 1485 12314 7517 Mix4_TiO2_Reinj_1_1 8481 12314 7517 Mix4_TiO2_Reinj_1_1 8481 Q96AY4 Q96AY4 Q96AY4 >sp|Q96AY4|TTC28_HUMAN Tetratricopeptide repeat protein 28 OS=Homo sapiens GN=TTC28 PE=1 SV=4 1 79.4259 1 79.4259 0.0030872 79.426 1 S LSLLNLSPRHNKK CDK1;NEK6;Proline-directed 0.0057 0.0030872 79.426 _DVLSLLNLpSPR_ DVLSLLNLS(1)PR DVLS(-79.43)LLNLS(79.43)PR 9 2 653.84196 0.16484 62449 0 0 0 62449 0 0 0 1989 1384 28 28 1721;4858;5022 1936;5523;5712 48496 29665 Mix4_TiO2_Reinj_1_1 6845 15791 9559 Mix4_TiO2_Reinj_1_1 7561 Q96AY4 Q96AY4 Q96AY4 >sp|Q96AY4|TTC28_HUMAN Tetratricopeptide repeat protein 28 OS=Homo sapiens GN=TTC28 PE=1 SV=4 0.99254 21.2406 0.8505 7.55036 0.0334132 58.89 0 0 0.99254 21.2406 1.3309E-32 183.78 1 S RRREPESPPASAP ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.000145 1.3309E-32 183.78 _RREPEpSPPASAPIPLFGADTIGQR_ RREPES(0.993)PPAS(0.007)APIPLFGADTIGQR RREPES(21.24)PPAS(-21.24)APIPLFGADT(-61.96)IGQR 6 3 881.44106 -1.219 539240 63015 0 0 476220 0 0 0 1990 1384 2104 2104 2447 2775 23012 14385 Mix4_TiO2_Reinj_1_1 2660 23012 14385 Mix4_TiO2_Reinj_1_1 2660 Q96AY4 Q96AY4 Q96AY4 >sp|Q96AY4|TTC28_HUMAN Tetratricopeptide repeat protein 28 OS=Homo sapiens GN=TTC28 PE=1 SV=4 0.999649 36.3563 0.999649 36.3563 0.070606 42.524 2 S SSKGSISTPNSPV GSK3 0.081 0.070606 42.524 _GSIpSTPNpSPVK_ GSIS(1)T(0.005)PNS(0.995)PVK GS(-36.36)IS(36.36)T(-23.41)PNS(23.41)PVK 4 2 623.75945 -0.08166 56990 0 0 0 56990 0 0 0 1991 1384 2108 2108 2447 2775 23012 14385 Mix4_TiO2_Reinj_1_1 2660 23012 14385 Mix4_TiO2_Reinj_1_1 2660 Q96AY4 Q96AY4 Q96AY4 >sp|Q96AY4|TTC28_HUMAN Tetratricopeptide repeat protein 28 OS=Homo sapiens GN=TTC28 PE=1 SV=4 0.995348 23.4071 0.995348 23.4071 0.070606 42.524 2 S SISTPNSPVKMTL CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.070606 42.524 _GSIpSTPNpSPVK_ GSIS(1)T(0.005)PNS(0.995)PVK GS(-36.36)IS(36.36)T(-23.41)PNS(23.41)PVK 8 2 623.75945 -0.08166 56990 0 0 0 56990 0 0 0 1992 1385 129 129 2642 3005 24644 15272 Mix4_TiO2_Reinj_1_4 1771 24644 15272 Mix4_TiO2_Reinj_1_4 1771 Q96BR1 Q96BR1 Q96BR1 >sp|Q96BR1|SGK3_HUMAN Serine/threonine-protein kinase Sgk3 OS=Homo sapiens GN=SGK3 PE=1 SV=1 0.93722 11.7402 0 0 0.93722 11.7402 0.0120515 69.526 1 S KHQSDPSEDEDER CK1;CK2 0.081 0.0120515 69.526 _HQSDPpSEDEDER_ HQS(0.063)DPS(0.937)EDEDER HQS(-11.74)DPS(11.74)EDEDER 6 2 762.26774 -0.53316 77011 0 0 0 77011 0 0 0 1993 1386 74 74 124;125 145;146 1260 798 Mix4_TiO2_Reinj_1_2 3580 1260 798 Mix4_TiO2_Reinj_1_2 3580 Q96C19 Q96C19 Q96C19 >sp|Q96C19|EFHD2_HUMAN EF-hand domain-containing protein D2 OS=Homo sapiens GN=EFHD2 PE=1 SV=1 0.977301 16.3402 0 0 0.977301 16.3402 0.00258575 81.933 1 S GIGEPQSPSRRVF CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00258575 81.933 _ADLNQGIGEPQpSPSR_ ADLNQGIGEPQS(0.977)PS(0.023)R ADLNQGIGEPQS(16.34)PS(-16.34)R 12 2 824.86997 0.89915 39887 0 0 0 39887 0 0 0 1994 1387 303 303 3409 3851 32065 19817 Mix4_TiO2_Reinj_1_2 4565 32065 19817 Mix4_TiO2_Reinj_1_2 4565 Q96C36 Q96C36 Q96C36 >sp|Q96C36|P5CR2_HUMAN Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens GN=PYCR2 PE=1 SV=1 0.46694 0 0 0 0.46694 0 0.0196535 65.031 1 S VSTLTPSSPGKLL CK1;NEK6 0.076 0.0196535 65.031 _LESPTVSTLTPpSSPGK_ LESPTVST(0.001)LT(0.065)PS(0.467)S(0.467)PGK LES(-65.03)PT(-56.22)VS(-33.34)T(-25.28)LT(-8.6)PS(0)S(0)PGK 12 2 840.90823 0.40212 0 0 0 0 0 0 0 0 1995 1387 304 304 3409 3851 32065 19817 Mix4_TiO2_Reinj_1_2 4565 32065 19817 Mix4_TiO2_Reinj_1_2 4565 Q96C36 Q96C36 Q96C36 >sp|Q96C36|P5CR2_HUMAN Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens GN=PYCR2 PE=1 SV=1 0.46694 0 0 0 0.46694 0 0.0196535 65.031 1 S STLTPSSPGKLLT CDK1;CDK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0196535 65.031 _LESPTVSTLTPpSSPGK_ LESPTVST(0.001)LT(0.065)PS(0.467)S(0.467)PGK LES(-65.03)PT(-56.22)VS(-33.34)T(-25.28)LT(-8.6)PS(0)S(0)PGK 13 2 840.90823 0.40212 0 0 0 0 0 0 0 0 1996 1389 127 127 3386 3827 31895 19736 Mix4_InSol_TiO2_1 4085 31901 19742 Mix4_TiO2_Reinj_1_4 3675 Q96CB8 Q96CB8 Q96CB8 >sp|Q96CB8|INT12_HUMAN Integrator complex subunit 12 OS=Homo sapiens GN=INTS12 PE=1 SV=1 0.941819 12.1908 0.67757 3.2329 8.18407E-17 172.83 0 0 0.675127 3.20726 1.50773E-33 216.22 0.941819 12.1908 7.35489E-05 98.218 0.261197 -4.50051 0.0665819 54.118 1 S EKPETQSSPITVQ 1.50773E-33 216.22 _LEKPETQpSSPITVQSSK_ LEKPET(0.001)QS(0.942)S(0.057)PITVQSSK LEKPET(-28.7)QS(12.19)S(-12.19)PIT(-43.6)VQS(-74.62)S(-81.57)K 8 3 646.98551 -0.22561 686100 116400 0 0 482770 0 86933 0 1997 1389 128 128 3386 3827 31898 19739 Mix4_TiO2_1_4 3187 31901 19742 Mix4_TiO2_Reinj_1_4 3675 Q96CB8 Q96CB8 Q96CB8 >sp|Q96CB8|INT12_HUMAN Integrator complex subunit 12 OS=Homo sapiens GN=INTS12 PE=1 SV=1 0.859479 8.67262 0.859479 8.67262 8.18407E-17 172.83 0 0 0.762348 5.06315 1.50773E-33 216.22 0.05687 -12.1908 7.35489E-05 98.218 0.736239 4.50051 0.0665819 54.118 1 S KPETQSSPITVQS Polo box;Proline-directed 0.00405 1.50773E-33 216.22 _LEKPETQSpSPITVQSSK_ LEKPETQS(0.117)S(0.859)PIT(0.024)VQSSK LEKPET(-41.01)QS(-8.67)S(8.67)PIT(-15.58)VQS(-46.25)S(-53.03)K 9 2 969.97463 0.28878 527730 125850 0 0 344990 0 0 56890 1998 1390 896 896 3706 4179 34945 21648 Mix4_TiO2_Reinj_1_3 4812 34945 21648 Mix4_TiO2_Reinj_1_3 4812 Q96CW5 Q96CW5 Q96CW5 >sp|Q96CW5|GCP3_HUMAN Gamma-tubulin complex component 3 OS=Homo sapiens GN=TUBGCP3 PE=1 SV=2 0.999984 48.0037 0.998994 29.9705 0.338818 29.971 0 0 0.999984 48.0037 0.101365 48.004 0 0 0 0 1 S EPRLRVSLGTRGR AURORA;AURORA-1;NEK6;PKA 0.020748 0.101365 48.004 _LRVpSLGTR_ LRVS(1)LGTR LRVS(48)LGT(-48)R 4 2 491.26569 -0.11966 220540 34683 0 0 185860 0 0 0 1999 1390 515 515 5091 5792 49248 30054 Mix4_TiO2_Reinj_1_4 9220 49247 30053 Mix4_TiO2_Reinj_1_4 9210 Q96CW5;Q96CW5-2 Q96CW5 Q96CW5 >sp|Q96CW5|GCP3_HUMAN Gamma-tubulin complex component 3 OS=Homo sapiens GN=TUBGCP3 PE=1 SV=2;>sp|Q96CW5-2|GCP3_HUMAN Isoform 2 of Gamma-tubulin complex component 3 OS=Homo sapiens GN=TUBGCP3 0.859235 7.85616 0 0 0.859235 7.85616 8.13434E-17 144.76 1 S VTKSAESPQDAAD CK1;CK2;Proline-directed 0.05 8.13434E-17 144.76 _SAEpSPQDAADLFTDLENAFQGK_ S(0.141)AES(0.859)PQDAADLFTDLENAFQGK S(-7.86)AES(7.86)PQDAADLFT(-85.01)DLENAFQGK 4 3 812.01972 -0.41722 173910 0.15758 0 0 0 173910 0 0 0 2000 1391 468 468 1181 1326 11088 6792 Mix4_InSol_TiO2_1 4817 11088 6792 Mix4_InSol_TiO2_1 4817 Q96D46 Q96D46 Q96D46 >sp|Q96D46|NMD3_HUMAN 60S ribosomal export protein NMD3 OS=Homo sapiens GN=NMD3 PE=1 SV=1 0.995198 23.1653 0.995198 23.1653 0.00701361 75.265 0.103151 -9.3856 0.557662 28 1 S SAIPVESDTDDEG CK2 0.117 0.00701361 75.265 _DSAIPVEpSDTDDEGAPR_ DSAIPVES(0.995)DT(0.005)DDEGAPR DS(-73.58)AIPVES(23.17)DT(-23.17)DDEGAPR 8 2 927.37547 0.76422 57243 0.27784 0 0 0 0 0 57243 0 2001 1394 7 7 141 166 1592 1122 Mix4_TiO2_1_4 2783 1592 1122 Mix4_TiO2_1_4 2783 Q96EC8 Q96EC8 Q96EC8 >sp|Q96EC8|YIPF6_HUMAN Protein YIPF6 OS=Homo sapiens GN=YIPF6 PE=2 SV=2 0.999985 48.1757 0.999985 48.1757 0.00937565 73.7 0 0 0.95926 13.7208 0.0428004 57.552 1 S MAEAEESPGDPGT CK2;Proline-directed 0.05 0.00937565 73.7 _(ac)AEAEEpSPGDPGTASPR_ AEAEES(1)PGDPGTASPR AEAEES(48.18)PGDPGT(-48.18)AS(-73.7)PR 6 2 846.84107 1.232 51511 23676 0 0 27835 0 0 0 2002 1396 6 6 3876 4398 36786 22659 Mix4_TiO2_Reinj_1_6 5997 36786 22659 Mix4_TiO2_Reinj_1_6 5997 Q96ET8;Q9NYZ1;Q96ET8-2 Q96ET8 Q96ET8 >sp|Q96ET8|F18B2_HUMAN Protein FAM18B2 OS=Homo sapiens GN=FAM18B2 PE=1 SV=3;>sp|Q9NYZ1|FA18B_HUMAN Protein FAM18B OS=Homo sapiens GN=FAM18B PE=2 SV=2;>sp|Q96ET8-2|F18B2_HUMAN Isoform 2 of Protein FAM18B2 OS=Homo sapiens GN=FAM18B2 0.984616 18.0809 0.984616 18.0809 0.0187582 66.585 1 S _MLQQDSNDDTED CK2 0.117 0.0187582 66.585 _(ac)M(ox)LQQDpSNDDTEDVSLFDAEEETTNRPR_ MLQQDS(0.985)NDDT(0.015)EDVSLFDAEEETTNRPR MLQQDS(18.08)NDDT(-18.08)EDVS(-41.69)LFDAEEET(-66.58)T(-66.58)NRPR 6 3 1098.4523 -0.50443 87820 0.045487 0 0 0 87820 0 0 0 2003 1400 295 295 2141 2426 19687 12036 Mix4_TiO2_Reinj_1_4 8542 19687 12036 Mix4_TiO2_Reinj_1_4 8542 Q96EZ8-2;Q96EZ8;Q96EZ8-3 Q96EZ8-2 Q96EZ8-2 >sp|Q96EZ8-2|MCRS1_HUMAN Isoform MCRS2 of Microspherule protein 1 OS=Homo sapiens GN=MCRS1;>sp|Q96EZ8|MCRS1_HUMAN Microspherule protein 1 OS=Homo sapiens GN=MCRS1 PE=1 SV=1;>sp|Q96EZ8-3|MCRS1_HUMAN Isoform 3 of Microspherule protein 1 OS=Homo sapiens GN=MC 1 125.294 1 125.294 4.4909E-21 166.32 1 S DQVLNFSDAEDLI CK2;NEK6 0.076 4.4909E-21 166.32 _GDQVLNFpSDAEDLIDDSK_ GDQVLNFS(1)DAEDLIDDSK GDQVLNFS(125.29)DAEDLIDDS(-125.29)K 8 2 1030.9384 0.2492 95660 0 0 0 95660 0 0 0 2004 1401 131 131 5614 6397 54872 33596 Mix4_InSol_Tio2_Reinj_1 2942 54871 33595 Mix4_InSol_TiO2_1 2944 Q96F86 Q96F86 Q96F86 >sp|Q96F86|EDC3_HUMAN Enhancer of mRNA-decapping protein 3 OS=Homo sapiens GN=EDC3 PE=1 SV=1 0.999813 38.2318 0.998313 27.7416 0.0755922 51.141 0.999813 38.2318 0.113123 44.385 1 S SQDVAVSPQQQQC Proline-directed 0.05 0.0755922 51.141 _SQDVAVpSPQQQQCSK_ SQDVAVS(1)PQQQQCSK S(-44.38)QDVAVS(38.23)PQQQQCS(-38.23)K 7 2 885.37984 0.42566 41858 0 0 0 0 0 22582 19276 2005 1404 341 341 3785 4277 35947 22254 Mix4_TiO2_Reinj_1_5 2192 35947 22254 Mix4_TiO2_Reinj_1_5 2192 Q96G23 Q96G23 Q96G23 >sp|Q96G23|LASS2_HUMAN LAG1 longevity assurance homolog 2 OS=Homo sapiens GN=LASS2 PE=1 SV=1 1 86.2303 0 0 0 0 1 86.2303 0.00124063 86.23 0 0 0 0 1 S LVEDERSDREETE CK2 0.117 0.00124063 86.23 _LVEDERpSDR_ LVEDERS(1)DR LVEDERS(86.23)DR 7 2 599.75862 -0.15305 1364800 0 0 0 1364800 0 0 0 2006 1405 7 7 437;1719 499;1934 4130 2472 Mix4_InSol_Tio2_Reinj_1 6770 15785 9556 Mix4_TiO2_1_4 5757 Q96GD4 Q96GD4 Q96GD4 >sp|Q96GD4|AURKB_HUMAN Serine/threonine-protein kinase 12 OS=Homo sapiens GN=AURKB PE=1 SV=2 0.989442 22.7285 0.982699 17.5437 0.00884585 59.627 0 0 0.909842 13.0499 0.654159 13.05 0.989442 22.7285 0.384273 22.729 1 S MAQKENSYPWPYG PLK1 0.033462 0.00884585 59.627 _(ac)AQKENpSYPWPYGR_ AQKENS(0.989)Y(0.005)PWPY(0.005)GR AQKENS(22.73)Y(-22.73)PWPY(-22.73)GR 6 2 859.37214 -0.13322 157510 58615 0 0 0 0 57205 41687 2007 1407 370 370 977 1099 9321 5703 Mix4_InSol_TiO2_1 7740 9330 5713 Mix4_TiO2_Reinj_1_5 7095 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 1 67.8879 0.999837 40.8803 9.43433E-08 117.17 0.999855 42.3493 0.000279352 91.18 0.999999 63.3025 6.66825E-16 140.25 1 67.8879 6.87005E-07 111.22 0.996719 26.123 0.138653 46.71 1 S DLELALSPIHNSS NEK6;Proline-directed 0.05 6.66825E-16 140.25 _DLELALpSPIHNSSALPTTGR_ DLELALS(1)PIHNSSALPTTGR DLELALS(67.89)PIHNS(-67.89)S(-74.21)ALPT(-97.16)T(-103.17)GR 7 2 1086.5385 0.38563 3939700 605630 144320 0 2591100 0 511160 87402 2008 1407 375 375 977 1099 9322 5704 Mix4_InSol_Tio2_Reinj_1 7679 9330 5713 Mix4_TiO2_Reinj_1_5 7095 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.854298 8.10784 0.000842191 -30.7376 9.43433E-08 117.17 0.00307333 -25.0971 0.000279352 91.18 0.134007 -8.08173 6.66825E-16 140.25 0.00904803 -20.3552 6.87005E-07 111.22 0.854298 8.10784 0.138653 46.71 1 S LSPIHNSSALPTT 6.66825E-16 140.25 _DLELALSPIHNpSSALPTTGR_ DLELALS(0.014)PIHNS(0.854)S(0.132)ALPTTGR DLELALS(-17.99)PIHNS(8.11)S(-8.11)ALPT(-44.63)T(-45.53)GR 12 3 724.69473 0.11083 302930 0 0 0 0 0 0 302930 2009 1407 619 619 1837 2074 16818 10124 Mix4_TiO2_1_5 6188 16818 10124 Mix4_TiO2_1_5 6188 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.499941 0 0.499941 0 1.29211E-25 161.06 0 0 1 S DCQEKTSPKGVEN CDK1;Proline-directed 0.0057 1.29211E-25 161.06 _ESSFEESNIEDPLIVTPDCQEKpTSPK_ ESSFEESNIEDPLIVTPDCQEKT(0.5)S(0.5)PK ES(-159.82)S(-159.82)FEES(-160.03)NIEDPLIVT(-36.3)PDCQEKT(0)S(0)PK 24 3 1020.4528 -0.29751 293770 293770 0 0 0 0 0 0 2010 1407 319 319 3318 3754 31328 19407 Mix4_TiO2_1_5 5037 31329 19408 Mix4_TiO2_Reinj_1_5 5703 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.499356 0 0.499356 0 0.000141777 90.87 0.157431 -7.2539 2.218E-07 107.34 1 S VESECHSSPKWEK CK1 0.143 2.218E-07 107.34 _LATSSASSQSHTFISSVESECHpSSPK_ LATSSASSQSHTFISSVES(0.001)ECHS(0.499)S(0.499)PK LAT(-90.87)S(-90.87)S(-90.87)AS(-89.05)S(-85.81)QS(-81.8)HT(-89.56)FIS(-68.44)S(-68.44)VES(-25.88)ECHS(0)S(0)PK 23 3 944.41117 0.15551 0 0 0 0 0 0 0 0 2011 1407 320 320 3318 3754 31329 19408 Mix4_TiO2_Reinj_1_5 5703 31329 19408 Mix4_TiO2_Reinj_1_5 5703 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.836526 7.2539 0.499356 0 0.000141777 90.87 0.836526 7.2539 2.218E-07 107.34 1 S ESECHSSPKWEKD CDK1;Polo box;Proline-directed 0.00405 2.218E-07 107.34 _LATSSASSQSHTFISSVESECHSpSPK_ LATSSASSQSHTFISSVES(0.006)ECHS(0.157)S(0.837)PK LAT(-105.34)S(-107.11)S(-107.34)AS(-99.61)S(-105.34)QS(-105.34)HT(-104.94)FIS(-90.12)S(-67.32)VES(-21.41)ECHS(-7.25)S(7.25)PK 24 3 944.41117 -0.66688 1056500 0 0 0 1056500 0 0 0 2012 1407 452 452 4016;4017 4573;4574 37960 23311 Mix4_TiO2_Reinj_1_3 5327 37961 23312 Mix4_TiO2_Reinj_1_5 5329 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.833228 6.98641 0.0118303 -19.2184 8.88326E-07 155.46 0 0 0.833228 6.98641 8.19561E-09 169.1 0.00108111 -29.6566 1.47103E-08 163.66 0.5 0 8.20722E-06 145.43 1 S NFELVDSSPCKKI NEK6 0.076 8.19561E-09 169.1 _NFELVDpSSPCKK_ NFELVDS(0.833)S(0.167)PCKK NFELVDS(6.99)S(-6.99)PCKK 7 3 501.88982 0.066899 2037200 0 0 0 1957500 0 0 79729 2013 1407 453 453 4016;4017 4573;4574 37953 23301 Mix4_InSol_TiO2_1 5678 37961 23312 Mix4_TiO2_Reinj_1_5 5329 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.998919 29.6566 0.993184 21.6351 8.88326E-07 155.46 0 0 0.985816 18.4201 8.19561E-09 169.1 0.998919 29.6566 1.47103E-08 163.66 0.989442 19.7183 8.20722E-06 145.43 1 S FELVDSSPCKKII CDK1;CDK2;Polo box;Proline-directed 0.00405 8.19561E-09 169.1 _NFELVDSpSPCKK_ NFELVDS(0.001)S(0.999)PCKK NFELVDS(-29.66)S(29.66)PCKK 8 2 752.3311 -0.02405 4062000 383650 0 0 2013500 0 892190 772610 2014 1408 274 274 1928 2180 17687 10572 Mix4_TiO2_Reinj_1_4 7800 17687 10572 Mix4_TiO2_Reinj_1_4 7800 Q96H12 Q96H12 Q96H12 >sp|Q96H12|CI030_HUMAN UPF0439 protein C9orf30 OS=Homo sapiens GN=C9orf30 PE=1 SV=1 1 93.383 1 110.602 4.31682E-07 125.67 0 0 1 93.383 6.61798E-10 153.89 0 0 1 S NRPFPNSP_____ ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 6.61798E-10 153.89 _EWPVSSFNRPFPNpSP_ EWPVSSFNRPFPNS(1)P EWPVS(-102.77)S(-93.38)FNRPFPNS(93.38)P 14 2 920.90635 1.0248 213490 57481 0 0 156010 0 0 0 2015 1408 96 96 5848 6668 57662 35089 Mix4_InSol_Tio2_Reinj_1 7041 57667 35094 Mix4_TiO2_Reinj_1_4 6486 Q96H12 Q96H12 Q96H12 >sp|Q96H12|CI030_HUMAN UPF0439 protein C9orf30 OS=Homo sapiens GN=C9orf30 PE=1 SV=1 0.832273 8.35631 0.400892 -1.74478 0.00673363 77.139 0 0 0.476882 -0.401576 0.00454449 80.392 0 0 0.832273 8.35631 0.579859 15.565 1 S REKVKRSVSPLLS AURORA;AURORA-1 0.020748 0.00454449 80.392 _pSVSPLLSTHVLGK_ S(0.832)VS(0.122)PLLS(0.023)T(0.023)HVLGK S(8.36)VS(-8.36)PLLS(-15.57)T(-15.57)HVLGK 1 2 709.37617 0.31171 94982 0 0 0 0 0 0 94982 2016 1408 98 98 5848 6668 57668 35095 Mix4_TiO2_Reinj_1_4 6517 57667 35094 Mix4_TiO2_Reinj_1_4 6486 Q96H12 Q96H12 Q96H12 >sp|Q96H12|CI030_HUMAN UPF0439 protein C9orf30 OS=Homo sapiens GN=C9orf30 PE=1 SV=1 0.999246 31.879 0.624435 2.20834 0.00673363 77.139 0 0 0.999246 31.879 0.00454449 80.392 0 0 0.121516 -8.35631 0.579859 15.565 1 S KVKRSVSPLLSTH CAMK2;CHK1;GSK3;PKA;PKD;Proline-directed 0.003024 0.00454449 80.392 _SVpSPLLSTHVLGK_ S(0.001)VS(0.999)PLLSTHVLGK S(-31.88)VS(31.88)PLLS(-40.77)T(-46.52)HVLGK 3 3 473.2532 -0.77263 984420 249570 0 0 734860 0 0 0 2017 1410 296 296 2875 3276 27501 17172 Mix4_TiO2_Reinj_1_4 5179 27491 17162 Mix4_InSol_Tio2_Reinj_1 5586 Q96I24 Q96I24 Q96I24 >sp|Q96I24|FUBP3_HUMAN Far upstream element-binding protein 3 OS=Homo sapiens GN=FUBP3 PE=1 SV=2 1 79.6187 1 69.3301 0.000529311 101.66 1 48.2712 0.0649928 48.271 1 79.6187 0.00366629 84.504 1 24.7178 0.000529311 101.66 1 9.85773 0.000402648 106.01 1 S KPDDGISPERAAQ CDK1;CDK2;Proline-directed 0.0057 0.000402648 106.01 _IQFKPDDGIpSPER_ IQFKPDDGIS(1)PER IQFKPDDGIS(79.62)PER 10 3 527.91514 -0.24775 4673700 975100 33070 0 3298900 0 227060 139580 2018 1410 569 569 4716 5357 44983 27558 Mix4_TiO2_Reinj_1_3 6006 44982 27557 Mix4_TiO2_1_4 5291 Q96I24;Q96I24-2 Q96I24 Q96I24 >sp|Q96I24|FUBP3_HUMAN Far upstream element-binding protein 3 OS=Homo sapiens GN=FUBP3 PE=1 SV=2;>sp|Q96I24-2|FUBP3_HUMAN Isoform 2 of Far upstream element-binding protein 3 OS=Homo sapiens GN=FUBP3 1 90.2853 1 118.548 5.55228E-11 132.54 0 0 1 90.2853 1.64069E-07 116.47 0.999793 39.083 0.0278048 59.124 1 78.2774 0.000432333 86.963 1 S GQAQAHSQEQ___ 5.55228E-11 132.54 _QQVAFYGQTLGQAQAHpSQEQ_ QQVAFYGQTLGQAQAHS(1)QEQ QQVAFY(-104.33)GQT(-90.29)LGQAQAHS(90.29)QEQ 17 3 767.00949 0.17387 1646300 0.031959 516230 0 0 460900 0 469740 199450 2019 1410 539 539 4731 5373 45089 27598 Mix4_InSol_TiO2_1 8219 45090 27599 Mix4_InSol_Tio2_Reinj_1 8203 Q96I24 Q96I24 Q96I24 >sp|Q96I24|FUBP3_HUMAN Far upstream element-binding protein 3 OS=Homo sapiens GN=FUBP3 PE=1 SV=2 0.981002 17.8532 0.981002 17.8532 0.0197553 64.004 0.924052 11.0528 0.000672193 79.279 1 S AAPQASSPPDYTM CK2;Polo box;Proline-directed 0.00405 0.000672193 79.279 _QSHAASAAPQASpSPPDYTMAWAEYYR_ QS(0.001)HAASAAPQAS(0.016)S(0.981)PPDY(0.001)TMAWAEYYR QS(-29.51)HAAS(-37.83)AAPQAS(-17.85)S(17.85)PPDY(-28.93)T(-34.2)MAWAEY(-48.34)Y(-48.34)R 13 3 979.41637 0.02521 405750 0 0 0 0 0 245170 160580 2020 1410 439 439 6412 7334 64730 39703 Mix4_TiO2_Reinj_1_4 6717 64729 39702 Mix4_TiO2_1_4 6679 Q96I24 Q96I24 Q96I24 >sp|Q96I24|FUBP3_HUMAN Far upstream element-binding protein 3 OS=Homo sapiens GN=FUBP3 PE=1 SV=2 0.971561 15.442 0.858239 7.82055 1.18299E-07 103.06 0.971561 15.442 0.0681712 60.616 1 S PGAFGQSPFSQPP Proline-directed 0.05 1.18299E-07 103.06 _VGGTNLGAPGAFGQpSPFSQPPAPPHQNTFPPR_ VGGT(0.001)NLGAPGAFGQS(0.972)PFS(0.028)QPPAPPHQNTFPPR VGGT(-31.54)NLGAPGAFGQS(15.44)PFS(-15.44)QPPAPPHQNT(-50.98)FPPR 15 4 827.89638 1.0652 636500 364520 0 0 271980 0 0 0 2021 1411 155 155 4977;4978 5659;5660 48030 29373 Mix4_TiO2_Reinj_1_4 3116 48030 29373 Mix4_TiO2_Reinj_1_4 3116 Q96I25 Q96I25 Q96I25 >sp|Q96I25|SPF45_HUMAN Splicing factor 45 OS=Homo sapiens GN=RBM17 PE=1 SV=1 1 132.617 1 77.1095 0.00160791 90.448 1 132.617 8.25644E-16 185.23 1 S RRPDPDSDEDEDY CK2 0.117 8.25644E-16 185.23 _RPDPDpSDEDEDYER_ RPDPDS(1)DEDEDYER RPDPDS(132.62)DEDEDY(-132.62)ER 6 2 909.32852 0.39497 455440 54435 0 0 401010 0 0 0 2022 1412 263 263 2116;2667 2400;3036 24926 15420 Mix4_TiO2_Reinj_1_4 3759 24926 15420 Mix4_TiO2_Reinj_1_4 3759 Q96IF1 Q96IF1 Q96IF1 >sp|Q96IF1|JUB_HUMAN Protein ajuba OS=Homo sapiens GN=JUB PE=1 SV=1 0.999649 34.552 0 0 0.999649 34.552 0.016118 67.49 0 0 0 0 1 S AQPGRHSVTGYGD AURORA;AURORA-1;PKA 0.020748 0.016118 67.49 _HpSVTGYGDCAVGAR_ HS(1)VTGYGDCAVGAR HS(34.55)VT(-34.55)GY(-61.89)GDCAVGAR 2 2 765.31377 1.1365 168900 0 0 0 168900 0 0 0 2023 1412 230 230 2668 3037 24929 15421 Mix4_TiO2_Reinj_1_4 6982 24929 15421 Mix4_TiO2_Reinj_1_4 6982 Q96IF1 Q96IF1 Q96IF1 >sp|Q96IF1|JUB_HUMAN Protein ajuba OS=Homo sapiens GN=JUB PE=1 SV=1 0.466661 0 0 0 0 0 0.466661 0 0.000228459 85.991 1 S CQESRHSYPPALG CK1;PKA 0.042 0.000228459 85.991 _HpSYPPALGSPGALAGAGVGAAGPLER_ HS(0.467)Y(0.467)PPALGS(0.067)PGALAGAGVGAAGPLER HS(0)Y(0)PPALGS(-8.45)PGALAGAGVGAAGPLER 2 3 818.40395 0.0084945 0 0 0 0 0 0 0 0 2024 1412 119 119 3398 3839 31983 19771 Mix4_TiO2_2_4 3950 31983 19771 Mix4_TiO2_2_4 3950 Q96IF1 Q96IF1 Q96IF1 >sp|Q96IF1|JUB_HUMAN Protein ajuba OS=Homo sapiens GN=JUB PE=1 SV=1 0.999996 54.1307 0.999949 42.8865 0.0693841 42.886 0.999996 54.1307 0.00748192 68.614 0.999982 47.356 0.0543138 47.356 0 0 0 0 1 S PTAPALSPRSSFA CDK1;GSK3;Proline-directed 0.0057 0.00748192 68.614 _LEPTAPALpSPR_ LEPTAPALS(1)PR LEPT(-54.13)APALS(54.13)PR 9 2 616.30775 0.12779 340990 62049 56098 0 222840 0 0 0 2025 1412 136 136 5702 6496 55899 34221 Mix4_InSol_Tio2_Reinj_1 3380 55899 34221 Mix4_InSol_Tio2_Reinj_1 3380 Q96IF1 Q96IF1 Q96IF1 >sp|Q96IF1|JUB_HUMAN Protein ajuba OS=Homo sapiens GN=JUB PE=1 SV=1 0.912569 10.186 0.491553 0 0.333159 35.944 0 0 0.692733 3.53255 1.51065E-15 148.07 0.847906 7.46793 0.00102193 86.424 0.912569 10.186 7.43572E-21 159.98 1 S SDASKPSSPRGSL CK1 0.081 7.43572E-21 159.98 _SSFASSSASDASKPpSSPR_ SSFASSSASDASKPS(0.913)S(0.087)PR S(-137.17)S(-136.28)FAS(-124.84)S(-118.45)S(-119.48)AS(-99.66)DAS(-65.69)KPS(10.19)S(-10.19)PR 15 2 918.394 0.14187 335820 0 0 0 90254 0 137600 107970 2026 1412 137 137 5702 6496 55904 34226 Mix4_TiO2_Reinj_1_4 3035 55899 34221 Mix4_InSol_Tio2_Reinj_1 3380 Q96IF1 Q96IF1 Q96IF1 >sp|Q96IF1|JUB_HUMAN Protein ajuba OS=Homo sapiens GN=JUB PE=1 SV=1 0.974619 15.8433 0.491553 0 0.333159 35.944 0 0 0.974619 15.8433 1.51065E-15 148.07 0.343878 0 0.00102193 86.424 0.478835 0 7.43572E-21 159.98 1 S DASKPSSPRGSLL CDK1;CK1;ERK/MAPK;GSK3;Polo box;Proline-directed;WW GroupIV 0.0023175 7.43572E-21 159.98 _SSFASSSASDASKPSpSPR_ SSFASSSASDASKPS(0.025)S(0.975)PR S(-140.73)S(-140.04)FAS(-127.78)S(-113.85)S(-107.03)AS(-92.93)DAS(-84.14)KPS(-15.84)S(15.84)PR 16 2 918.394 0.33318 561070 0 0 0 561070 0 0 0 2027 1418 1955 1955 6428 7352 64897 39805 Mix4_InSol_TiO2_1 2397 64898 39806 Mix4_TiO2_Reinj_1_1 1833 Q96JI7;Q96JI7-2 Q96JI7 Q96JI7 >sp|Q96JI7|SPTCS_HUMAN Spatacsin OS=Homo sapiens GN=SPG11 PE=1 SV=3;>sp|Q96JI7-2|SPTCS_HUMAN Isoform 2 of Spatacsin OS=Homo sapiens GN=SPG11 0.974507 16.5344 0 0 0.947123 15.2445 0.0663945 43.773 0.974507 16.5344 0.123396 36.887 0 0 1 S PLRRVHSTSSLDS CAMK2;CHK1;CHK1/2;PKD 0.003192 0.0663945 43.773 _VHpSTSSLDSQK_ VHS(0.975)T(0.022)S(0.003)SLDSQK VHS(16.53)T(-16.53)S(-24.51)S(-36.89)LDS(-36.89)QK 3 2 634.77956 1.2158 251790 0 0 0 85877 0 165910 0 2028 1418 1957 1957 6428 7352 64899 39807 Mix4_TiO2_Reinj_1_5 2370 64898 39806 Mix4_TiO2_Reinj_1_1 1833 Q96JI7;Q96JI7-2 Q96JI7 Q96JI7 >sp|Q96JI7|SPTCS_HUMAN Spatacsin OS=Homo sapiens GN=SPG11 PE=1 SV=3;>sp|Q96JI7-2|SPTCS_HUMAN Isoform 2 of Spatacsin OS=Homo sapiens GN=SPG11 0.493803 0 0 0 0.493803 0 0.0663945 43.773 0.00344923 -24.5106 0.123396 36.887 0 0 1 S RRVHSTSSLDSQK CK2;GSK3 0.081 0.0663945 43.773 _VHSTpSSLDSQK_ VHST(0.012)S(0.494)S(0.494)LDSQK VHS(-32.64)T(-16.17)S(0)S(0)LDS(-33.83)QK 5 2 634.77956 0.037286 0 0 0 0 0 0 0 0 2029 1418 1958 1958 6428 7352 64899 39807 Mix4_TiO2_Reinj_1_5 2370 64898 39806 Mix4_TiO2_Reinj_1_1 1833 Q96JI7;Q96JI7-2 Q96JI7 Q96JI7 >sp|Q96JI7|SPTCS_HUMAN Spatacsin OS=Homo sapiens GN=SPG11 PE=1 SV=3;>sp|Q96JI7-2|SPTCS_HUMAN Isoform 2 of Spatacsin OS=Homo sapiens GN=SPG11 0.493803 0 0 0 0.493803 0 0.0663945 43.773 0.000199556 -36.8872 0.123396 36.887 0 0 1 S RVHSTSSLDSQKF CK1 0.081 0.0663945 43.773 _VHSTpSSLDSQK_ VHST(0.012)S(0.494)S(0.494)LDSQK VHS(-32.64)T(-16.17)S(0)S(0)LDS(-33.83)QK 6 2 634.77956 0.037286 0 0 0 0 0 0 0 0 2030 1420 502 502 355 405 3309 1986 Mix4_TiO2_Reinj_1_5 5059 3309 1986 Mix4_TiO2_Reinj_1_5 5059 Q96JN8;Q96JN8-2 Q96JN8 Q96JN8 >sp|Q96JN8|NEUL4_HUMAN Neuralized-like protein 4 OS=Homo sapiens GN=NEURL4 PE=1 SV=2;>sp|Q96JN8-2|NEUL4_HUMAN Isoform 2 of Neuralized-like protein 4 OS=Homo sapiens GN=NEURL4 1 48.8744 1 10.0622 0.685751 10.062 1 48.8744 0.0442502 48.874 1 S AILRALSPEGALR CAMK2;CHK1;PKD;Proline-directed 0.020748 0.0442502 48.874 _ALpSPEGALR_ ALS(1)PEGALR ALS(48.87)PEGALR 3 2 497.24188 1.232 56075 8767.9 0 0 47307 0 0 0 2031 1421 619 619 3081 3502 29330 18298 Mix4_TiO2_Reinj_1_5 1858 29330 18298 Mix4_TiO2_Reinj_1_5 1858 Q96JQ2 Q96JQ2 Q96JQ2 >sp|Q96JQ2|CLMN_HUMAN Calmin OS=Homo sapiens GN=CLMN PE=1 SV=1 1 40.3932 1 40.3932 0.0719934 40.393 1 S AHKKKDSPEPQVK Proline-directed 0.05 0.0719934 40.393 _KKDpSPEPQVK_ KKDS(1)PEPQVK KKDS(40.39)PEPQVK 4 2 618.30521 -0.10402 55463 0 0 0 55463 0 0 0 2032 1423 20 20 12 20 180 110 Mix4_TiO2_Reinj_1_4 3691 180 110 Mix4_TiO2_Reinj_1_4 3691 Q96K37 Q96K37 Q96K37 >sp|Q96K37|S35E1_HUMAN Solute carrier family 35 member E1 OS=Homo sapiens GN=SLC35E1 PE=1 SV=2 0.499251 0 0 0 0.499251 0 0.000429822 84.371 1 S GPGAASSSGGARE 0.000429822 84.371 _(ac)AAAAVGAGHGAGGPGAASpSSGGAR_ AAAAVGAGHGAGGPGAAS(0.001)S(0.499)S(0.499)GGAR AAAAVGAGHGAGGPGAAS(-25.23)S(0)S(0)GGAR 19 3 662.9641 0.74271 0 0 0 0 0 0 0 0 0 2033 1423 21 21 12 20 180 110 Mix4_TiO2_Reinj_1_4 3691 180 110 Mix4_TiO2_Reinj_1_4 3691 Q96K37 Q96K37 Q96K37 >sp|Q96K37|S35E1_HUMAN Solute carrier family 35 member E1 OS=Homo sapiens GN=SLC35E1 PE=1 SV=2 0.499251 0 0 0 0.499251 0 0.000429822 84.371 1 S PGAASSSGGAREG 0.000429822 84.371 _(ac)AAAAVGAGHGAGGPGAASpSSGGAR_ AAAAVGAGHGAGGPGAAS(0.001)S(0.499)S(0.499)GGAR AAAAVGAGHGAGGPGAAS(-25.23)S(0)S(0)GGAR 20 3 662.9641 0.74271 0 0 0 0 0 0 0 0 0 2034 1426 754 754 4446 5056 42267 26014 Mix4_TiO2_Reinj_1_5 6915 42267 26014 Mix4_TiO2_Reinj_1_5 6915 Q96KG9;Q96KG9-2;Q96KG9-3 Q96KG9 Q96KG9 >sp|Q96KG9|NTKL_HUMAN N-terminal kinase-like protein OS=Homo sapiens GN=SCYL1 PE=1 SV=1;>sp|Q96KG9-2|NTKL_HUMAN Isoform Variant 1 of N-terminal kinase-like protein OS=Homo sapiens GN=SCYL1;>sp|Q96KG9-3|NTKL_HUMAN Isoform Variant 2 of N-terminal kinase-like 0.999998 58.2171 0.997584 29.1697 0.00239849 77.631 0.999998 58.2171 4.84241E-12 134.83 1 S TQPRPDSWGEDNW CAMK2;CK2 0.042 4.84241E-12 134.83 _PSTQPRPDpSWGEDNWEGLETDSR_ PSTQPRPDS(1)WGEDNWEGLETDSR PS(-66.48)T(-58.22)QPRPDS(58.22)WGEDNWEGLET(-103.33)DS(-119.22)R 9 3 913.71547 0.62056 1428400 3.4869 425380 0 0 1003100 0 0 0 2035 1428 432 432 4559 5178 43198 26497 Mix4_TiO2_Reinj_1_4 6897 43196 26493 Mix4_TiO2_Reinj_1_1 6256 Q96KQ4 Q96KQ4 Q96KQ4 >sp|Q96KQ4|ASPP1_HUMAN Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens GN=PPP1R13B PE=1 SV=3 0.995171 23.2689 0.455552 0 1.27192 11.868 0 0 0.995171 23.2689 0.125461 47.349 0 0 1 S SQPVPFSALGPTE 0.125461 47.349 _QGTVSSQPVPFpSALGPTEK_ QGTVSSQPVPFS(0.995)ALGPT(0.005)EK QGT(-43.27)VS(-43.27)S(-43.27)QPVPFS(23.27)ALGPT(-23.27)EK 12 3 670.65751 -0.20144 211480 0 0 0 211480 0 0 0 2036 1429 1054 1054 4831;4832;5019 5484;5485;5708 48473 29659 Mix4_TiO2_Reinj_1_5 4127 46130 28192 Mix4_TiO2_Reinj_1_5 4025 Q96KR1 Q96KR1 Q96KR1 >sp|Q96KR1|ZFR_HUMAN Zinc finger RNA-binding protein OS=Homo sapiens GN=ZFR PE=1 SV=2 1 62.3298 1 9.7893 1.0192 9.7893 1 62.3298 0.000635324 95.132 1 S RKRRRDSDGVDGF CAMK2;PKA 0.004788 0.000635324 95.132 _RRDpSDGVDGFEAEGK_ RRDS(1)DGVDGFEAEGK RRDS(62.33)DGVDGFEAEGK 4 3 573.2441 0.12793 498300 17859 0 0 480440 0 0 0 2037 1430 438 438 5047 5741 48802 29830 Mix4_TiO2_1_3 3154 48803 29831 Mix4_TiO2_Reinj_1_3 3698 Q96L34;Q96L34-2 Q96L34 Q96L34 >sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1;>sp|Q96L34-2|MARK4_HUMAN Isoform MARKL1S of MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 0.322238 0 0.322238 0 0.0224997 62.374 0.0452765 -8.46884 0.0189005 65.529 0 0 1 S PLHPKRSPTSTGE Proline-directed 0.05 0.0189005 65.529 _RpSPTSTGEAELKEER_ RS(0.322)PT(0.322)S(0.322)T(0.033)GEAELKEER RS(0)PT(0)S(0)T(-9.86)GEAELKEER 2 3 590.60703 0.29562 0 0 0 0 0 0 0 0 2038 1430 441 441 5047 5741 48802 29830 Mix4_TiO2_1_3 3154 48803 29831 Mix4_TiO2_Reinj_1_3 3698 Q96L34;Q96L34-2 Q96L34 Q96L34 >sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1;>sp|Q96L34-2|MARK4_HUMAN Isoform MARKL1S of MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 0.322238 0 0.322238 0 0.0224997 62.374 0.318241 0 0.0189005 65.529 0 0 1 S PKRSPTSTGEAEL CK1;CK2 0.081 0.0189005 65.529 _RpSPTSTGEAELKEER_ RS(0.322)PT(0.322)S(0.322)T(0.033)GEAELKEER RS(0)PT(0)S(0)T(-9.86)GEAELKEER 5 3 590.60703 0.29562 0 0 0 0 0 0 0 0 2039 1431 770 770 6612 7570 67097 41176 Mix4_TiO2_2_2 3778 67097 41176 Mix4_TiO2_2_2 3778 Q96L42 Q96L42 Q96L42 >sp|Q96L42|KCNH8_HUMAN Potassium voltage-gated channel subfamily H member 8 OS=Homo sapiens GN=KCNH8 PE=2 SV=2 0.526187 0 0.526187 0 0.125621 35.949 2 S HSPIRVSRSNSPK GSK3;PKA 0.042 0.125621 35.949 _VpSRpSNSPKTK_ VS(0.526)RS(0.947)NS(0.526)PKTK VS(0)RS(9.55)NS(0)PKT(-35.95)K 2 2 632.27834 -0.29271 231020 0 231020 0 0 0 0 0 2040 1431 772 772 6612 7570 67097 41176 Mix4_TiO2_2_2 3778 67097 41176 Mix4_TiO2_2_2 3778 Q96L42 Q96L42 Q96L42 >sp|Q96L42|KCNH8_HUMAN Potassium voltage-gated channel subfamily H member 8 OS=Homo sapiens GN=KCNH8 PE=2 SV=2 0.947265 9.55277 0.947265 9.55277 0.125621 35.949 2 S PIRVSRSNSPKTK 0.125621 35.949 _VpSRpSNSPKTK_ VS(0.526)RS(0.947)NS(0.526)PKTK VS(0)RS(9.55)NS(0)PKT(-35.95)K 4 2 632.27834 -0.29271 231020 0 231020 0 0 0 0 0 2041 1431 774 774 6612 7570 67097 41176 Mix4_TiO2_2_2 3778 67097 41176 Mix4_TiO2_2_2 3778 Q96L42 Q96L42 Q96L42 >sp|Q96L42|KCNH8_HUMAN Potassium voltage-gated channel subfamily H member 8 OS=Homo sapiens GN=KCNH8 PE=2 SV=2 0.526187 0 0.526187 0 0.125621 35.949 2 S RVSRSNSPKTKQE CAMK2;CDK1;CHK1;CK1;PKD;Proline-directed 0.0057 0.125621 35.949 _VpSRpSNSPKTK_ VS(0.526)RS(0.947)NS(0.526)PKTK VS(0)RS(9.55)NS(0)PKT(-35.95)K 6 2 632.27834 -0.29271 231020 0 231020 0 0 0 0 0 2042 1433 137 137 6127 6993;6994 60504 36585 Mix4_TiO2_1_6 2141 60504 36585 Mix4_TiO2_1_6 2141 Q96LL9 Q96LL9 Q96LL9 >sp|Q96LL9|DJC30_HUMAN DnaJ homolog subfamily C member 30 OS=Homo sapiens GN=DNAJC30 PE=1 SV=3 0.897826 9.43952 0.897826 9.43952 0.0233938 61.204 0.0324341 -14.6786 0.324417 35.542 0.926035 18.4512 0.865682 18.451 0 0 0 0 1 S PAPDPGSPRTPPP CDK1;ERK/MAPK;Proline-directed 0.0025 0.0233938 61.204 _TPAPDPGpSPRTPPPTSR_ TPAPDPGS(0.898)PRT(0.102)PPPTSR T(-61.2)PAPDPGS(9.44)PRT(-9.44)PPPT(-48.95)S(-48.95)R 8 3 604.28764 -0.28124 187700 28222 0 0 159480 0 0 0 2043 1434 113 113 2555 2901 23928 14847 Mix4_TiO2_Reinj_1_6 3672 23928 14847 Mix4_TiO2_Reinj_1_6 3672 Q96LW7-2 Q96LW7-2 Q96LW7-2 >sp|Q96LW7-2|BINCA_HUMAN Isoform 2 of Bcl10-interacting CARD protein OS=Homo sapiens GN=C9orf89 0.993162 22.0072 0.773132 6.19271 0.0357189 58.87 0.993162 22.0072 2.42338E-12 136.11 1 S TELDSGSQSGELS 2.42338E-12 136.11 _HALQNSDCTELDSGpSQSGELSNR_ HALQNSDCTELDS(0.001)GS(0.993)QS(0.006)GELSNR HALQNS(-81.67)DCT(-64.8)ELDS(-32.33)GS(22.01)QS(-22.01)GELS(-85.25)NR 15 3 862.35718 -1.0197 126110 0.033005 28731 0 0 97377 0 0 0 2044 1436 308 308 2284 2582 21037 12883 Mix4_TiO2_Reinj_1_5 6827 21034 12879 Mix4_TiO2_1_3 5978 Q96MU7;Q96MU7-2 Q96MU7 Q96MU7 >sp|Q96MU7|YTDC1_HUMAN YTH domain-containing protein 1 OS=Homo sapiens GN=YTHDC1 PE=1 SV=3;>sp|Q96MU7-2|YTDC1_HUMAN Isoform 2 of YTH domain-containing protein 1 OS=Homo sapiens GN=YTHDC1 1 37.6246 1 41.6421 0.00509289 68.438 1 37.6246 0.0442628 48.871 0 0 0 0 1 S KRARGISPIVFDR CAMK2;PKA/AKT;Proline-directed 0.001764 0.00509289 68.438 _GIpSPIVFDR_ GIS(1)PIVFDR GIS(37.62)PIVFDR 3 2 542.26536 -0.26247 330770 73270 0 0 257500 0 0 0 2045 1437 671 671 2664 3031 24867 15383 Mix4_TiO2_1_5 3888 24867 15383 Mix4_TiO2_1_5 3888 Q96N46 Q96N46 Q96N46 >sp|Q96N46|TTC14_HUMAN Tetratricopeptide repeat protein 14 OS=Homo sapiens GN=TTC14 PE=1 SV=1 0.989686 19.9037 0.989686 19.9037 0.000208342 112.71 0 0 0 0 0 0 0 0 1 S SVRHSTSPASSEY GSK3;Proline-directed 0.05 0.000208342 112.71 _HSTpSPASSEYSWK_ HST(0.01)S(0.99)PASSEYSWK HS(-50.36)T(-19.9)S(19.9)PAS(-41.15)S(-39.53)EY(-88.55)S(-91.55)WK 4 2 773.81413 0.31028 72685 72685 0 0 0 0 0 0 2046 1438 284 284 232;233 266;268 2284 1476 Mix4_TiO2_2_2 3059 2281 1471 Mix4_TiO2_1_3 3245 Q96N66;Q96N66-2;Q96N66-3 Q96N66 Q96N66 >sp|Q96N66|MBOA7_HUMAN Lysophospholipid acyltransferase 7 OS=Homo sapiens GN=MBOAT7 PE=1 SV=2;>sp|Q96N66-2|MBOA7_HUMAN Isoform 2 of Lysophospholipid acyltransferase 7 OS=Homo sapiens GN=MBOAT7;>sp|Q96N66-3|MBOA7_HUMAN Isoform 3 of Lysophospholipid acyltran 0.690824 3.49162 0.55738 1.0012 3.56987E-13 152.61 0.690824 3.49162 0.00185922 81.113 0.499993 0 2.54392E-06 113.28 0 0 0.650444 2.69693 1.30691E-06 115.62 0.499958 0 0.000109841 91.785 1 S LQCPPPSSPEKAA CK2 0.117 3.56987E-13 152.61 _AGGGPTLQCPPPpSSPEK_ AGGGPTLQCPPPS(0.691)S(0.309)PEK AGGGPT(-81.11)LQCPPPS(3.49)S(-3.49)PEK 13 2 880.38968 -0.28112 2525000 7.3833 434490 41215 0 45102 0 650540 1353700 2047 1438 285 285 232;233 266;268 2281 1471 Mix4_TiO2_1_3 3245 2281 1471 Mix4_TiO2_1_3 3245 Q96N66;Q96N66-2;Q96N66-3 Q96N66 Q96N66 >sp|Q96N66|MBOA7_HUMAN Lysophospholipid acyltransferase 7 OS=Homo sapiens GN=MBOAT7 PE=1 SV=2;>sp|Q96N66-2|MBOA7_HUMAN Isoform 2 of Lysophospholipid acyltransferase 7 OS=Homo sapiens GN=MBOAT7;>sp|Q96N66-3|MBOA7_HUMAN Isoform 3 of Lysophospholipid acyltran 0.979075 16.7015 0.979075 16.7015 3.56987E-13 152.61 0.309176 -3.49162 0.00185922 81.113 0.739393 4.5289 2.54392E-06 113.28 0 0 0.644993 3.584 1.30691E-06 115.62 0.499958 0 0.000109841 91.785 1 S QCPPPSSPEKAAS CDK1;CDK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 3.56987E-13 152.61 _AGGGPTLQCPPPSpSPEK_ AGGGPTLQCPPPS(0.021)S(0.979)PEK AGGGPT(-143.55)LQCPPPS(-16.7)S(16.7)PEK 14 2 880.38968 0.1138 4857600 14.204 1597700 0 0 1841900 0 64363 1353700 2048 1439 898 898 5470 6226 53356 32599 Mix4_TiO2_Reinj_1_1 4241 53355 32598 Mix4_TiO2_1_5 4107 Q96N67;Q96N67-6;Q96N67-2;Q96N67-5;Q96N67-3;Q96N67-4 Q96N67 Q96N67 >sp|Q96N67|DOCK7_HUMAN Dedicator of cytokinesis protein 7 OS=Homo sapiens GN=DOCK7 PE=1 SV=4;>sp|Q96N67-6|DOCK7_HUMAN Isoform 6 of Dedicator of cytokinesis protein 7 OS=Homo sapiens GN=DOCK7;>sp|Q96N67-2|DOCK7_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.580922 4.42858 0.418138 1.57531 8.70713E-24 164.79 0 0 0.580922 4.42858 5.33248E-12 136.08 0 0 0.416035 1.53793 1.46683E-23 157.12 1 S NRSRSLSNSNPDI CAMK2;CK1;PKA/AKT 0.00111111 8.70713E-24 164.79 _SLpSNSNPDISGTPTSPDDEVR_ S(0.21)LS(0.581)NS(0.21)NPDISGTPTSPDDEVR S(-4.43)LS(4.43)NS(-4.43)NPDIS(-50.58)GT(-75.14)PT(-74.25)S(-106.69)PDDEVR 3 2 1134.4868 0.81904 267430 0 0 0 267430 0 0 0 2049 1440 544 544 2650 3014 24717 15300 Mix4_TiO2_Reinj_1_3 5548 24716 15299 Mix4_TiO2_1_3 4766 Q96NE9;Q96NE9-2;Q96NE9-3 Q96NE9 Q96NE9 >sp|Q96NE9|FRMD6_HUMAN FERM domain-containing protein 6 OS=Homo sapiens GN=FRMD6 PE=1 SV=1;>sp|Q96NE9-2|FRMD6_HUMAN Isoform 2 of FERM domain-containing protein 6 OS=Homo sapiens GN=FRMD6;>sp|Q96NE9-3|FRMD6_HUMAN Isoform 3 of FERM domain-containing protein 0.999997 54.866 0.999839 37.9363 0.000954949 78.781 0.999997 54.866 0.0223907 55.796 1 S TDRHSLSLDDIRL CK2 0.117 0.000954949 78.781 _HSLpSLDDIR_ HSLS(1)LDDIR HS(-54.87)LS(54.87)LDDIR 4 2 568.2608 0.17587 545500 113480 0 0 432020 0 0 0 2050 1442 2085 2085 6263 7154 62376 37954 Mix4_TiO2_2_4 5435 62376 37954 Mix4_TiO2_2_4 5435 Q96PK2;Q9UPN3;Q9UPN3-1;Q9UPN3-4 Q96PK2 Q96PK2 >sp|Q96PK2|MACF4_HUMAN Microtubule-actin cross-linking factor 1, isoform 4 OS=Homo sapiens GN=MACF1 PE=1 SV=2;>sp|Q9UPN3|MACF1_HUMAN Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens GN=MACF1 PE=1 SV=3;>sp|Q9UPN3-1|MACF1_HUMAN Isof 0.99859 32.648 0.972627 16.1869 0.591654 26.902 0.99859 32.648 0.123062 45.902 0.972212 19.6667 0.3506 34.696 1 S TTQQDLSALQKNQ 0.123062 45.902 _TTQQDLpSALQKNQSDLK_ TTQQDLS(0.999)ALQKNQS(0.001)DLK T(-33.98)T(-33.29)QQDLS(32.65)ALQKNQS(-32.65)DLK 7 2 999.48061 0.47029 1533600 388140 713120 0 432360 0 0 0 2051 1443 571 571 2385 2699;2701 22160 13825 Mix4_InSol_Tio2_Reinj_1 7111 22165 13832 Mix4_TiO2_Reinj_1_3 6782 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.49972 0 0.495563 0 8.68195E-07 108.14 0.0495171 -12.7556 6.7099E-26 161.27 0.354023 0 0.00178906 85.092 0.49972 0 9.36249E-07 107.35 1 S AVANANSTPPPYE 6.7099E-26 161.27 _GQPGNAYDGAGQPSAAYLSMSQGAVANANpSTPPPYER_ GQPGNAYDGAGQPSAAYLSMSQGAVANANS(0.5)T(0.5)PPPYER GQPGNAY(-63.67)DGAGQPS(-53.52)AAY(-42.68)LS(-39.17)MS(-33.59)QGAVANANS(0)T(0)PPPY(-32.98)ER 30 4 944.41771 -0.38589 0 0 0 0 0 0 0 0 0 2052 1443 618 618 3718;4940 4192;5616 47501 28992 Mix4_InSol_TiO2_1 6026 47502 28993 Mix4_TiO2_1_3 4850 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.996429 24.6807 0.982698 17.5433 0.000794766 79.404 0 0 0.986454 19.2851 0.00101291 78.732 0.996429 24.6807 0.107513 37.45 0.00852467 -18.483 0.00736776 75.777 1 S SDYRRLSESQLSF CAMK2;PKA;PKA/AKT 0.00111111 0.000794766 79.404 _RLpSESQLSFR_ RLS(0.996)ES(0.003)QLSFR RLS(24.68)ES(-24.68)QLS(-37.45)FR 3 2 651.81373 -0.1477 1541700 269910 0 0 1117600 0 154250 0 2053 1443 623 623 3718;4940 4192;5616 35086 21733 Mix4_InSol_Tio2_Reinj_1 5106 47502 28993 Mix4_TiO2_1_3 4850 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.780562 7.79684 0.0380782 -13.8492 0.000794766 79.404 0 0 0.0019158 -27.1173 0.00101291 78.732 0.408658 -0.983982 0.107513 37.45 0.780562 7.79684 0.00736776 75.777 1 S LSESQLSFRRSPT CK1;GSK3 0.081 0.000794766 79.404 _LSESQLpSFRRSPTK_ LSESQLS(0.781)FRRS(0.09)PT(0.13)K LS(-75.78)ES(-61.45)QLS(7.8)FRRS(-9.39)PT(-7.8)K 7 3 572.62073 -0.080493 3564900 0 0 0 0 0 0 3564900 2054 1443 627 627 3718;5045;5590 4192;5738;6371 54672 33481 Mix4_InSol_TiO2_1 3694 35086 21733 Mix4_InSol_Tio2_Reinj_1 5106 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.999972 45.4986 0 0 0 0 0 0 0.999972 45.4986 0.00281086 73.187 0.999953 43.3234 0.00736776 75.777 1 S QLSFRRSPTKSSL CDK1;CDK2;CK1;GSK3;NIMA;PKA;Proline-directed 0.001741464 0.00736776 75.777 _pSPTKSSLDYR_ S(1)PTKSSLDYR S(45.5)PT(-45.5)KS(-73.19)S(-73.19)LDY(-73.19)R 1 2 617.27919 0.29118 6267900 0 0 0 0 0 5569300 698600 2055 1443 220 220 5572 6349 54504 33377 Mix4_InSol_TiO2_1 6285 54504 33377 Mix4_InSol_TiO2_1 6285 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.333333 0 0 0 0.333333 0 0.0106926 70.017 0.322404 -0.532845 0.0188216 61.916 1 S RSPLRRSPPRASY CDK1;CDK2;NEK6;NIMA;PKA;Proline-directed 0.001741464 0.0106926 70.017 _pSPPRASYVAPLTAQPATYR_ S(0.333)PPRAS(0.333)Y(0.333)VAPLTAQPATYR S(0)PPRAS(0)Y(0)VAPLT(-55.62)AQPAT(-70.02)Y(-70.02)R 1 3 709.35253 0.86565 0 0 0 0 0 0 0 0 2056 1443 225 225 5572 6349 54505 33378 Mix4_InSol_Tio2_Reinj_1 6247 54504 33377 Mix4_InSol_TiO2_1 6285 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.463127 0 0 0 0.333333 0 0.0106926 70.017 0.463127 0 0.0188216 61.916 1 S RSPPRASYVAPLT PKA 0.042 0.0106926 70.017 _SPPRApSYVAPLTAQPATYR_ S(0.074)PPRAS(0.463)Y(0.463)VAPLTAQPATYR S(-7.98)PPRAS(0)Y(0)VAPLT(-61.16)AQPAT(-61.92)Y(-61.92)R 6 3 709.35253 0.33897 0 0 0 0 0 0 0 0 2057 1446 499 499 1277 1440;1441 12036 7375 Mix4_TiO2_Reinj_1_5 3616 12036 7375 Mix4_TiO2_Reinj_1_5 3616 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4;Q96PU5-3 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.573672 1.29136 0.573672 1.29136 5.17363E-11 119.9 2 S TLSNPQSPQPSPY CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 5.17363E-11 119.9 _DTLSNPQpSPQPSPYNpSPKPQHK_ DTLSNPQS(0.574)PQPS(0.426)PY(0.019)NS(0.981)PKPQHK DT(-97.77)LS(-78.14)NPQS(1.29)PQPS(-1.29)PY(-17.09)NS(17.09)PKPQHK 8 3 869.71406 -1.1088 152060 0 0 0 152060 0 0 0 2058 1446 507 507 1277 1440;1441 12036 7375 Mix4_TiO2_Reinj_1_5 3616 12036 7375 Mix4_TiO2_Reinj_1_5 3616 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4;Q96PU5-3 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.980649 17.0892 0.980649 17.0892 5.17363E-11 119.9 2 S QPSPYNSPKPQHK CDK1;CK1;Proline-directed 0.0057 5.17363E-11 119.9 _DTLSNPQpSPQPSPYNpSPKPQHK_ DTLSNPQS(0.574)PQPS(0.426)PY(0.019)NS(0.981)PKPQHK DT(-97.77)LS(-78.14)NPQS(1.29)PQPS(-1.29)PY(-17.09)NS(17.09)PKPQHK 16 3 869.71406 -1.1088 152060 0 0 0 152060 0 0 0 2059 1446 466 466 5474 6230 53374 32608 Mix4_InSol_TiO2_1 7317 53387 32624 Mix4_TiO2_Reinj_1_5 6813 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.89071 9.11671 0.569175 1.50952 2.61896E-09 130.23 0.39931 -0.898327 0.561748 27.868 0.542412 2.99132 1.65313E-09 132.86 0 0 0.89071 9.11671 4.46122E-09 125.21 0.882967 8.78558 7.2865E-06 104.29 1 S QIRRPRSLSSPTV CAMK2;CHK1;PKD 0.020748 1.65313E-09 132.86 _pSLSSPTVTLSAPLEGAK_ S(0.891)LS(0.109)SPTVTLSAPLEGAK S(9.12)LS(-9.12)S(-38.37)PT(-64.53)VT(-79.36)LS(-95.49)APLEGAK 1 2 869.43715 0.050358 5123100 25733 0 0 2968500 0 1085200 1043800 2060 1446 468 468 5474 6230 53380 32615 Mix4_TiO2_1_5 5895 53387 32624 Mix4_TiO2_Reinj_1_5 6813 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.929365 11.2416 0.929365 11.2416 2.61896E-09 130.23 0.491069 0.898327 0.561748 27.868 0.835275 7.11692 1.65313E-09 132.86 0 0 0.295819 0 4.46122E-09 125.21 0.473513 0 7.2865E-06 104.29 1 S RRPRSLSSPTVTL 14-3-3 binding;CAMK2;PKA/AKT 0.0001701 1.65313E-09 132.86 _SLpSSPTVTLSAPLEGAK_ S(0.07)LS(0.929)S(0.001)PTVTLSAPLEGAK S(-11.24)LS(11.24)S(-30.61)PT(-70.51)VT(-96.71)LS(-105.42)APLEGAK 3 2 869.43715 -0.19121 1121600 816400 0 0 305230 0 0 0 2061 1446 469 469 5474 6230 53385 32622 Mix4_TiO2_Reinj_1_3 6894 53387 32624 Mix4_TiO2_Reinj_1_5 6813 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.318357 0 0.0103202 -16.8077 2.61896E-09 130.23 0.106594 -6.63409 0.561748 27.868 0.318357 0 1.65313E-09 132.86 0 0 0.295819 0 4.46122E-09 125.21 0.257002 0 7.2865E-06 104.29 1 S RPRSLSSPTVTLS CK1;Polo box;Proline-directed 0.00405 1.65313E-09 132.86 _SLpSSPTVTLSAPLEGAK_ S(0.004)LS(0.318)S(0.318)PT(0.318)VT(0.041)LSAPLEGAK S(-19.36)LS(0)S(0)PT(0)VT(-8.88)LS(-55.72)APLEGAK 4 3 579.96053 -0.44876 0 0 0 0 0 0 0 0 2062 1447 1154 1154 1760 1987 16282 9846 Mix4_TiO2_Reinj_1_5 5682 16282 9846 Mix4_TiO2_Reinj_1_5 5682 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.99924 31.2007 0.971403 15.3294 7.00316E-06 108.32 0.992337 21.1302 7.56137E-06 107.54 0.99924 31.2007 1.41807E-08 118.59 0 0 0.986264 18.5831 1.10536E-05 102.63 0.996675 24.7764 1.01131E-05 103.94 1 S QPGEEYSEEEESV CK2 0.117 1.41807E-08 118.59 _EQPGEEYpSEEEESVLK_ EQPGEEY(0.001)S(0.999)EEEESVLK EQPGEEY(-31.2)S(31.2)EEEES(-56.49)VLK 8 2 981.39862 -0.12934 4186800 42.225 861400 65532 0 2716200 0 284800 258810 2063 1447 896 896 3259 3694 30844 19143 Mix4_TiO2_Reinj_1_5 5814 30844 19143 Mix4_TiO2_Reinj_1_5 5814 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.999652 34.5866 0.997542 26.0854 5.71223E-07 106.86 0.999652 34.5866 3.35635E-12 136.26 1 S PSAIVDSPVETKS CK2;ERK/MAPK;Proline-directed 0.0034 3.35635E-12 136.26 _KVQCISHEINPSAIVDpSPVETK_ KVQCISHEINPSAIVDS(1)PVETK KVQCIS(-136.26)HEINPS(-72.53)AIVDS(34.59)PVET(-34.59)K 17 3 844.41189 -0.094618 545710 94815 0 0 450890 0 0 0 2064 1447 834 834 4823 5473 46055 28160 Mix4_TiO2_Reinj_1_5 4684 46055 28160 Mix4_TiO2_Reinj_1_5 4684 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.998861 29.4431 0.998861 29.4431 0.0394859 55.202 1 S RRAWGKSPTDSVL CK2;GSK3;Proline-directed 0.05 0.0394859 55.202 _RAWGKpSPTDSVLK_ RAWGKS(0.999)PT(0.001)DSVLK RAWGKS(29.44)PT(-29.44)DS(-55.2)VLK 6 3 508.92386 -0.34304 120920 0 0 0 120920 0 0 0 2065 1447 865 865 5221;5222 5943;5944 50639 31006 Mix4_TiO2_1_5 2097 50639 31006 Mix4_TiO2_1_5 2097 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.999998 57.6274 0.999998 57.6274 0.00799352 61.187 0 0 0.999164 30.7729 0.211973 30.773 0.995586 23.837 0.0897918 51.159 0 0 1 S TIRSEISPEGEKY CK1;Proline-directed 0.05 0.00799352 61.187 _SEIpSPEGEK_ SEIS(1)PEGEK S(-57.63)EIS(57.63)PEGEK 4 2 528.21827 0.090392 914140 160740 0 0 550060 0 203340 0 2066 1447 694 694 5692;5693 6483;6484;6485 55748 34164 Mix4_TiO2_1_5 3106 55748 34164 Mix4_TiO2_1_5 3106 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.744031 4.63658 0.744031 4.63658 7.87298E-16 149.26 0 0 0.371454 0 0.00479451 75.894 0 0 0.200714 -5.10261 1.38329 22.703 1 S ETGGSPSKQQMRS 7.87298E-16 149.26 _SSDVSPPLGQHETGGSPpSK_ SSDVSPPLGQHETGGS(0.256)PS(0.744)K S(-149.26)S(-149.26)DVS(-138.6)PPLGQHET(-36.95)GGS(-4.64)PS(4.64)K 18 2 973.92821 -0.28863 218440 218440 0 0 0 0 0 0 2067 1447 1080 1080 5921 6753 58340 35409 Mix4_TiO2_Reinj_1_1 4431 58341 35410 Mix4_TiO2_Reinj_1_5 4958 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.999798 38.6478 0.994028 22.2138 0.0069294 63.847 0 0 0.999798 38.6478 0.00366892 71.997 0 0 0.997527 29.0667 0.235894 29.067 0.997999 28.7793 0.0871727 39.675 1 S KMLRTCSLPDLSK CAMK2;CHK1;CK2 0.0228 0.00366892 71.997 _TCpSLPDLSK_ TCS(1)LPDLSK T(-38.65)CS(38.65)LPDLS(-41.86)K 3 2 550.73831 0.17029 4710600 597860 0 0 2378800 0 1142900 591050 2068 1448 3566 3566 4114 4684;4685 38995 23923 Mix4_InSol_Tio2_Reinj_1 4847 39001 23930 Mix4_TiO2_Reinj_1_1 3931 Q96Q15;Q96Q15-2;Q96Q15-3;Q96Q15-4 Q96Q15 Q96Q15 >sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1 PE=1 SV=2;>sp|Q96Q15-2|SMG1_HUMAN Isoform 2 of Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1;>sp|Q96Q15-3|SMG1_HUMAN Isoform 3 of Serine/threonine-protein kin 0.994032 24.3338 0.962658 14.1149 4.77683E-06 104.69 0.101854 -8.15542 0.781467 22.582 0.931838 13.3461 1.0712E-10 135.06 0.336797 -2.34215 0.141403 44.057 0.978312 16.5579 8.32694E-10 119.42 0.994032 24.3338 9.04747E-07 115.57 1 S QKNLATSADTPPS NEK6 0.076 1.0712E-10 135.06 _NLATpSADTPPSTVPGTGK_ NLAT(0.004)S(0.994)ADT(0.002)PPSTVPGTGK NLAT(-24.33)S(24.33)ADT(-26.36)PPS(-55.65)T(-55.65)VPGT(-87.04)GK 5 2 897.41949 1.5133 529070 71938 0 0 165040 0 244360 47737 2069 1448 3572 3572 4114 4684;4685 39003 23932 Mix4_TiO2_Reinj_2_1 3195 39001 23930 Mix4_TiO2_Reinj_1_1 3931 Q96Q15;Q96Q15-2;Q96Q15-3;Q96Q15-4 Q96Q15 Q96Q15 >sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1 PE=1 SV=2;>sp|Q96Q15-2|SMG1_HUMAN Isoform 2 of Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1;>sp|Q96Q15-3|SMG1_HUMAN Isoform 3 of Serine/threonine-protein kin 0.577542 2.34215 0.32752 -2.97487 3.58425E-06 108.03 0.105126 -8.01811 0.781467 22.582 0.497742 0 1.61073E-06 113.57 0.577542 2.34215 0.141403 44.057 0.319001 0.950341 8.32694E-10 119.42 0.174341 -3.56784 9.04747E-07 115.57 1 S SADTPPSTVPGTG 1.0712E-10 135.06 _NLATSADTPPpSTVPGTGK_ NLAT(0.015)S(0.337)ADT(0.067)PPS(0.578)T(0.003)VPGTGK NLAT(-15.84)S(-2.34)ADT(-9.35)PPS(2.34)T(-22.2)VPGT(-41.31)GK 11 2 897.41949 1.1026 19632 0 0 0 0 19632 0 0 2070 1448 3552 3552 5533;6181 6302;6303;7058 61229 37093 Mix4_TiO2_Reinj_1_1 1770 54130 33132 Mix4_TiO2_Reinj_1_1 2724 Q96Q15;Q96Q15-2;Q96Q15-3;Q96Q15-4 Q96Q15 Q96Q15 >sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1 PE=1 SV=2;>sp|Q96Q15-2|SMG1_HUMAN Isoform 2 of Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1;>sp|Q96Q15-3|SMG1_HUMAN Isoform 3 of Serine/threonine-protein kin 0.999952 43.23 0.982483 19.4254 0.831953 19.425 0.999952 43.23 0.117384 46.728 0 0 0 0 1 S TQPDVMSQNARKL 0.117384 46.728 _TQPDVM(ox)pSQNAR_ TQPDVMS(1)QNAR T(-43.23)QPDVMS(43.23)QNAR 7 2 671.77649 0.64384 81121 0 0 0 81121 0 0 0 2071 1449 75 75 5518 6282 53862 32940 Mix4_TiO2_Reinj_1_4 4951 53862 32940 Mix4_TiO2_Reinj_1_4 4951 Q96Q40;Q96Q40-3;Q96Q40-4;Q96Q40-2 Q96Q40 Q96Q40 >sp|Q96Q40|CDK15_HUMAN Cell division protein kinase 15 OS=Homo sapiens GN=CDK15 PE=1 SV=2;>sp|Q96Q40-3|CDK15_HUMAN Isoform 3 of Cell division protein kinase 15 OS=Homo sapiens GN=CDK15;>sp|Q96Q40-4|CDK15_HUMAN Isoform 4 of Cell division protein kinase 15 O 0.5 0 0 0 0.5 0 0.000502236 110.98 1 S KSKRPRSNSDCFQ CAMK2;CK2;PKA 0.003024 0.000502236 110.98 _pSNSDCFQEEDLR_ S(0.5)NS(0.5)DCFQEEDLR S(0)NS(0)DCFQEEDLR 1 2 790.29016 0.4696 144960 0 0 0 144960 0 0 0 2072 1449 77 77 5518 6282 53862 32940 Mix4_TiO2_Reinj_1_4 4951 53862 32940 Mix4_TiO2_Reinj_1_4 4951 Q96Q40;Q96Q40-3;Q96Q40-4;Q96Q40-2 Q96Q40 Q96Q40 >sp|Q96Q40|CDK15_HUMAN Cell division protein kinase 15 OS=Homo sapiens GN=CDK15 PE=1 SV=2;>sp|Q96Q40-3|CDK15_HUMAN Isoform 3 of Cell division protein kinase 15 OS=Homo sapiens GN=CDK15;>sp|Q96Q40-4|CDK15_HUMAN Isoform 4 of Cell division protein kinase 15 O 0.5 0 0 0 0.5 0 0.000502236 110.98 1 S KRPRSNSDCFQEE CAMK2;PKA/AKT 0.001764 0.000502236 110.98 _pSNSDCFQEEDLR_ S(0.5)NS(0.5)DCFQEEDLR S(0)NS(0)DCFQEEDLR 3 2 790.29016 0.4696 144960 0 0 0 144960 0 0 0 2073 1450 483 483 4947 5623 47585 29047 Mix4_TiO2_Reinj_1_5 7969 47585 29047 Mix4_TiO2_Reinj_1_5 7969 Q96Q42;Q96Q42-3 Q96Q42 Q96Q42 >sp|Q96Q42|ALS2_HUMAN Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2;>sp|Q96Q42-3|ALS2_HUMAN Isoform 3 of Alsin OS=Homo sapiens GN=ALS2 0.989868 19.8984 0.989868 19.8984 0.0978087 42.652 2 S GGSRRLSLPGLLS AURORA;AURORA-1;AURORA-A;CAMK2;CK1;PKA 0.004788 0.0978087 42.652 _RLpSLPGLLSQVpSPR_ RLS(0.99)LPGLLS(0.01)QVS(1)PR RLS(19.9)LPGLLS(-19.9)QVS(42.65)PR 3 3 561.61787 -0.42506 67983 0 0 0 67983 0 0 0 2074 1450 492 492 4947 5623 47585 29047 Mix4_TiO2_Reinj_1_5 7969 47585 29047 Mix4_TiO2_Reinj_1_5 7969 Q96Q42;Q96Q42-3 Q96Q42 Q96Q42 >sp|Q96Q42|ALS2_HUMAN Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2;>sp|Q96Q42-3|ALS2_HUMAN Isoform 3 of Alsin OS=Homo sapiens GN=ALS2 0.999946 42.6518 0.999946 42.6518 0.0978087 42.652 2 S GLLSQVSPRLLRK CDK1;CK1;Proline-directed 0.0057 0.0978087 42.652 _RLpSLPGLLSQVpSPR_ RLS(0.99)LPGLLS(0.01)QVS(1)PR RLS(19.9)LPGLLS(-19.9)QVS(42.65)PR 12 3 561.61787 -0.42506 67983 0 0 0 67983 0 0 0 2075 1450 1462 1462 5244 5969 50919 31219 Mix4_TiO2_Reinj_1_5 8996 50919 31219 Mix4_TiO2_Reinj_1_5 8996 Q96Q42 Q96Q42 Q96Q42 >sp|Q96Q42|ALS2_HUMAN Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2 0.469345 0 0.442016 -0.999172 0.000138733 94.696 0.469345 0 2.30855E-17 146.74 1 S GKSDSRSESPEPG CK1 0.143 2.30855E-17 146.74 _pSESPEPGYVVTSSGLLLPVLLPR_ S(0.469)ES(0.469)PEPGY(0.061)VVTSSGLLLPVLLPR S(0)ES(0)PEPGY(-8.84)VVT(-44.26)S(-52.47)S(-60.55)GLLLPVLLPR 1 3 830.7679 0.045926 0 0 0 0 0 0 0 0 2076 1450 1464 1464 5244 5969 50920 31220 Mix4_TiO2_Reinj_1_5 9003 50919 31219 Mix4_TiO2_Reinj_1_5 8996 Q96Q42 Q96Q42 Q96Q42 >sp|Q96Q42|ALS2_HUMAN Alsin OS=Homo sapiens GN=ALS2 PE=1 SV=2 0.755006 4.88795 0.556359 0.999172 0.000138733 94.696 0.755006 4.88795 2.30855E-17 146.74 1 S SDSRSESPEPGYV CAMK2;CK1;Proline-directed 0.042 2.30855E-17 146.74 _SEpSPEPGYVVTSSGLLLPVLLPR_ S(0.245)ES(0.755)PEPGYVVTSSGLLLPVLLPR S(-4.89)ES(4.89)PEPGY(-69.33)VVT(-84.12)S(-88.42)S(-93.64)GLLLPVLLPR 3 2 1245.6482 0.23678 395590 126730 0 0 268860 0 0 0 2077 1452 15 15 3787 4279 35967 22265 Mix4_TiO2_2_5 1955 35968 22266 Mix4_TiO2_Reinj_1_2 2654 Q96QD9;Q96QD9-4 Q96QD9 Q96QD9 >sp|Q96QD9|UIF_HUMAN UAP56-interacting factor OS=Homo sapiens GN=FYTTD1 PE=1 SV=3;>sp|Q96QD9-4|UIF_HUMAN Isoform 4 of UAP56-interacting factor OS=Homo sapiens GN=FYTTD1 0.469274 0 0.0341204 -14.4972 0.00422925 81.868 0.469274 0 0.338187 25.601 0.182419 -6.38253 0.00226277 91.075 0 0 1 S VGATATSSPPPKA 0.00226277 91.075 _LVGATATpSSPPPK_ LVGAT(0.002)AT(0.059)S(0.469)S(0.469)PPPK LVGAT(-23.6)AT(-8.98)S(0)S(0)PPPK 8 2 653.32614 -0.024982 0 0 0 0 0 0 0 0 2078 1452 16 16 3787 4279 35965 22262 Mix4_TiO2_1_2 2043 35968 22266 Mix4_TiO2_Reinj_1_2 2654 Q96QD9;Q96QD9-4 Q96QD9 Q96QD9 >sp|Q96QD9|UIF_HUMAN UAP56-interacting factor OS=Homo sapiens GN=FYTTD1 PE=1 SV=3;>sp|Q96QD9-4|UIF_HUMAN Isoform 4 of UAP56-interacting factor OS=Homo sapiens GN=FYTTD1 0.961026 14.4972 0.961026 14.4972 0.00422925 81.868 0.469274 0 0.338187 25.601 0.793091 6.38253 0.00226277 91.075 0 0 1 S GATATSSPPPKAR CK1;Polo box;Proline-directed 0.00405 0.00226277 91.075 _LVGATATSpSPPPK_ LVGATAT(0.005)S(0.034)S(0.961)PPPK LVGAT(-55.39)AT(-22.97)S(-14.5)S(14.5)PPPK 9 2 653.32614 0.16889 109750 29466 0 0 80288 0 0 0 2079 1454 1361 1361 1521 1710 14037 8559 Mix4_TiO2_Reinj_1_1 7997 14037 8559 Mix4_TiO2_Reinj_1_1 7997 Q96QT4 Q96QT4 Q96QT4 >sp|Q96QT4|TRPM7_HUMAN Transient receptor potential cation channel subfamily M member 7 OS=Homo sapiens GN=TRPM7 PE=1 SV=1 0.998996 29.9794 0.988019 19.2627 0.465754 40.369 0.998996 29.9794 9.20448E-08 115.19 1 S LFPSAVSPPELRQ CK1;CK2;Proline-directed 0.05 9.20448E-08 115.19 _EFNFPEAGSSSGALFPSAVpSPPELR_ EFNFPEAGSSSGALFPS(0.001)AVS(0.999)PPELR EFNFPEAGS(-91.65)S(-90.85)S(-90.85)GALFPS(-29.98)AVS(29.98)PPELR 20 3 891.74593 0.1392 68821 17851 0 0 50970 0 0 0 2080 1455 199 199 2666 3033;3034;3035 24891 15393 Mix4_TiO2_1_5 7412 24898 15404 Mix4_TiO2_Reinj_1_6 7088 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.495965 0 0.495965 0 7.55206E-08 108.48 0 0 0.347574 -0.982131 5.17015E-08 111.54 0 0 2 S TVWDKHSVTAATP AURORA;AURORA-1 0.020748 5.17015E-08 111.54 _HpSVTAATPPPpSPTSGESGDLLSNLLQSPSSAK_ HS(0.496)VT(0.496)AAT(0.024)PPPS(0.788)PT(0.195)S(0.001)GESGDLLSNLLQSPSSAK HS(0)VT(0)AAT(-17.25)PPPS(6.08)PT(-6.08)S(-30.22)GES(-35.88)GDLLS(-50.07)NLLQS(-63.2)PS(-66.32)S(-66.32)AK 2 2 1647.2524 0.34758 0 0 0 0 0 0 0 0 2081 1455 208 208 2666 3033;3034;3035 24897 15402 Mix4_TiO2_Reinj_1_5 8139 24898 15404 Mix4_TiO2_Reinj_1_6 7088 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.83656 9.26211 0.835796 7.21662 7.55206E-08 108.48 0 0 0.83656 9.26211 5.17015E-08 111.54 0 0 2 S AATPPPSPTSGES CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 5.17015E-08 111.54 _HSVpTAATPPPpSPTSGESGDLLSNLLQSPSSAK_ HS(0.348)VT(0.423)AAT(0.225)PPPS(0.837)PT(0.128)S(0.034)GES(0.004)GDLLS(0.001)NLLQSPSSAK HS(-0.98)VT(0.98)AAT(-3.42)PPPS(9.26)PT(-9.26)S(-15.26)GES(-25.24)GDLLS(-27.61)NLLQS(-39.67)PS(-43.27)S(-43.27)AK 11 2 1647.2524 0.71828 7283200 5215600 0 0 2067600 0 0 0 2082 1455 211 211 2666 3033;3034;3035 24913 15412 Mix4_TiO2_Reinj_1_5 7920 24913 15412 Mix4_TiO2_Reinj_1_5 7920 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.3631 0.659738 0.319686 -1.13419 7.55206E-08 108.48 0 0 0.3631 0.659738 0.000149888 91.652 0 0 1 S PPPSPTSGESGDL CK1 0.081 0.000149888 91.652 _HSVTAATPPPSPTpSGESGDLLSNLLQSPSSAK_ HSVTAATPPPS(0.312)PT(0.312)S(0.363)GES(0.012)GDLLS(0.001)NLLQSPSSAK HS(-36.65)VT(-36.65)AAT(-30.46)PPPS(-0.66)PT(-0.66)S(0.66)GES(-14.8)GDLLS(-28.36)NLLQS(-69.24)PS(-73.71)S(-78.37)AK 14 3 1071.8486 0.064837 0 0 0 0 0 0 0 0 2083 1455 214 214 2666 3033;3034;3035 24915 15415 Mix4_TiO2_Reinj_1_6 6933 24913 15412 Mix4_TiO2_Reinj_1_5 7920 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.506435 5.4142 0.277396 0 0.000279246 85.455 0 0 0.506435 5.4142 0.000149888 91.652 0 0 1 S SPTSGESGDLLSN CK1 0.081 0.000149888 91.652 _HSVTAATPPPSPTSGEpSGDLLSNLLQSPSSAK_ HS(0.001)VTAAT(0.001)PPPS(0.146)PT(0.146)S(0.146)GES(0.506)GDLLS(0.055)NLLQSPSSAK HS(-27.8)VT(-32.03)AAT(-27.38)PPPS(-5.41)PT(-5.41)S(-5.41)GES(5.41)GDLLS(-9.66)NLLQS(-49.81)PS(-57.51)S(-60.81)AK 17 3 1071.8486 -0.081179 72871 0 0 0 72871 0 0 0 2084 1459 495 495 3204;5264 3634;5992 51089 31282 Mix4_TiO2_Reinj_1_4 6348 51089 31282 Mix4_TiO2_Reinj_1_4 6348 Q96RR4;Q96RR4-7;Q96RR4-4;Q96RR4-3;Q96RR4-2;Q96RR4-5;Q96RR4-6 Q96RR4 Q96RR4 >sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2 OS=Homo sapiens GN=CAMKK2 PE=1 SV=1;>sp|Q96RR4-7|KKCC2_HUMAN Isoform 7 of Calcium/calmodulin-dependent protein kinase kinase 2 OS=Homo sapiens GN=CAMKK2;>sp|Q96RR4-4|KKCC2_HUMAN Is 0.999999 59.0858 0.999997 55.5218 0.0212458 55.522 0.999999 59.0858 0.0104819 59.086 0 0 0.960288 13.8348 0.503626 13.835 1 S TMIRKRSFGNPFE AURORA;AURORA-A;CAMK2;CHK1;PKA 0.004788 0.0104819 59.086 _pSFGNPFEGSR_ S(1)FGNPFEGSR S(59.09)FGNPFEGS(-59.09)R 1 2 589.23733 -0.15208 211160 58741 0 0 131740 0 0 20674 2085 1464 153 153 4973 5655 47987 29337 Mix4_TiO2_Reinj_1_3 2081 47987 29337 Mix4_TiO2_Reinj_1_3 2081 Q96S55;Q96S55-2 Q96S55 Q96S55 >sp|Q96S55|WRIP1_HUMAN ATPase WRNIP1 OS=Homo sapiens GN=WRNIP1 PE=1 SV=2;>sp|Q96S55-2|WRIP1_HUMAN Isoform 2 of ATPase WRNIP1 OS=Homo sapiens GN=WRNIP1 0.999858 38.463 0 0 0.999858 38.463 0.0780844 47.336 1 S AAAGSASPRSWDE CDK1;Proline-directed 0.0057 0.0780844 47.336 _RPAAAAAAGSApSPR_ RPAAAAAAGSAS(1)PR RPAAAAAAGS(-38.46)AS(38.46)PR 12 2 667.32226 0.0035642 285980 0 0 0 285980 0 0 0 2086 1466 51 51 2424 2747 22724 14184 Mix4_InSol_TiO2_1 6602 22724 14184 Mix4_InSol_TiO2_1 6602 Q96SB4 Q96SB4 Q96SB4 >sp|Q96SB4|SRPK1_HUMAN Serine/threonine-protein kinase SRPK1 OS=Homo sapiens GN=SRPK1 PE=1 SV=2 1 82.6699 0.999997 56.4285 8.11253E-08 109.03 0 0 1 66.6155 1.6915E-12 122.2 1 82.6699 1.24756E-12 126.17 0.99999 52.6288 0.000287002 86.705 1 S EEEILGSDDDEQE CK2 0.117 1.24756E-12 126.17 _GSAPHSESDLPEQEEEILGpSDDDEQEDPNDYCK_ GSAPHSESDLPEQEEEILGS(1)DDDEQEDPNDYCK GS(-93.3)APHS(-88.76)ES(-88.76)DLPEQEEEILGS(82.67)DDDEQEDPNDY(-82.67)CK 20 3 1272.1617 0.64769 9215600 4601300 0 0 4106200 0 205170 302890 2087 1468 1196 1196 6820 7804 69139 42386 Mix4_TiO2_Reinj_1_3 5851 69139 42386 Mix4_TiO2_Reinj_1_3 5851 Q96SN8;Q96SN8-2;Q96SN8-3;Q96SN8-4 Q96SN8 Q96SN8 >sp|Q96SN8|CK5P2_HUMAN CDK5 regulatory subunit-associated protein 2 OS=Homo sapiens GN=CDK5RAP2 PE=1 SV=5;>sp|Q96SN8-2|CK5P2_HUMAN Isoform 2 of CDK5 regulatory subunit-associated protein 2 OS=Homo sapiens GN=CDK5RAP2;>sp|Q96SN8-3|CK5P2_HUMAN Isoform 3 of C 1 52.1571 1 31.0328 0.560224 31.033 1 52.1571 0.0863651 52.157 2 S APEMIDSRVLENL 0.0863651 52.157 _pYVKHVKILGPLAPEMIDpSR_ Y(1)VKHVKILGPLAPEMIDS(1)R Y(52.16)VKHVKILGPLAPEMIDS(52.16)R 18 3 776.05252 0.26437 1605600 420880 0 0 1184700 0 0 0 2088 1471 294 294 5471 6227 53366 32603 Mix4_TiO2_Reinj_1_5 5392 53366 32603 Mix4_TiO2_Reinj_1_5 5392 Q96T37;Q96T37-3;Q96T37-2 Q96T37 Q96T37 >sp|Q96T37|RBM15_HUMAN Putative RNA-binding protein 15 OS=Homo sapiens GN=RBM15 PE=1 SV=2;>sp|Q96T37-3|RBM15_HUMAN Isoform RBM15S of Putative RNA-binding protein 15 OS=Homo sapiens GN=RBM15;>sp|Q96T37-2|RBM15_HUMAN Isoform RBM15L of Putative RNA-binding pr 0.992618 21.2861 0.990568 20.2153 0.039703 53.863 0.992618 21.2861 0.00946804 74.192 0 0 0 0 1 S GGQRSLSPGGAAL CAMK2;Proline-directed 0.042 0.00946804 74.192 _SLpSPGGAALGYR_ S(0.007)LS(0.993)PGGAALGYR S(-21.29)LS(21.29)PGGAALGY(-74.19)R 3 2 614.78973 0.021583 672880 142910 0 0 529970 0 0 0 2089 1472 1027 1027 2181 2469 20035 12337 Mix4_TiO2_1_3 8654 20036 12338 Mix4_TiO2_Reinj_1_3 9205 Q96T76;Q96T76-4;Q96T76-5 Q96T76 Q96T76 >sp|Q96T76|MMS19_HUMAN MMS19 nucleotide excision repair protein homolog OS=Homo sapiens GN=MMS19 PE=1 SV=2;>sp|Q96T76-4|MMS19_HUMAN Isoform 3 of MMS19 nucleotide excision repair protein homolog OS=Homo sapiens GN=MMS19;>sp|Q96T76-5|MMS19_HUMAN Isoform 4 of 0.99981 37.2211 0.99981 37.2211 0.0606231 45.484 0.934961 11.5762 0.0270498 55.442 1 S EWFLLGSPGS___ NEK6;Proline-directed 0.05 0.0270498 55.442 _GEWFLLGpSPGS_ GEWFLLGS(1)PGS GEWFLLGS(37.22)PGS(-37.22) 8 2 615.26555 -0.0827 104640 40260 0 0 64380 0 0 0 2090 1472 1030 1030 2181 2469 20036 12338 Mix4_TiO2_Reinj_1_3 9205 20036 12338 Mix4_TiO2_Reinj_1_3 9205 Q96T76;Q96T76-4;Q96T76-5 Q96T76 Q96T76 >sp|Q96T76|MMS19_HUMAN MMS19 nucleotide excision repair protein homolog OS=Homo sapiens GN=MMS19 PE=1 SV=2;>sp|Q96T76-4|MMS19_HUMAN Isoform 3 of MMS19 nucleotide excision repair protein homolog OS=Homo sapiens GN=MMS19;>sp|Q96T76-5|MMS19_HUMAN Isoform 4 of 0.611811 1.97574 0.000189587 -37.2211 0.0606231 45.484 0.611811 1.97574 0.0270498 55.442 1 S LLGSPGS______ CK1 0.081 0.0270498 55.442 _GEWFLLGSPGpS_ GEWFLLGS(0.388)PGS(0.612) GEWFLLGS(-1.98)PGS(1.98) 11 2 615.26555 0.063611 200520 0 0 0 200520 0 0 0 2091 1474 678 678 61 72;73 572 365 Mix4_TiO2_1_3 6409 576 369 Mix4_TiO2_Reinj_1_3 7126 Q96TA1 Q96TA1 Q96TA1 >sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=2 0.995532 22.9377 0.995532 22.9377 0.138359 46.718 0 0 0.650634 0.735439 0.00903433 70.074 0 0 0 0 2 S KAAPEASSPPASP 0.00903433 70.074 _AAPEApSpSPPASPLQHLLPGK_ AAPEAS(0.996)S(0.883)PPAS(0.121)PLQHLLPGK AAPEAS(22.94)S(8.76)PPAS(-8.76)PLQHLLPGK 6 3 710.00071 0.004618 1698000 604450 0 0 1093500 0 0 0 2092 1474 679 679 61 72;73 572 365 Mix4_TiO2_1_3 6409 576 369 Mix4_TiO2_Reinj_1_3 7126 Q96TA1 Q96TA1 Q96TA1 >sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=2 0.883208 8.76446 0.883208 8.76446 0.138359 46.718 0 0 0.586167 -0.735439 0.00903433 70.074 0 0 0 0 2 S AAPEASSPPASPL GSK3;Polo box;Proline-directed 0.00405 0.00903433 70.074 _AAPEApSpSPPASPLQHLLPGK_ AAPEAS(0.996)S(0.883)PPAS(0.121)PLQHLLPGK AAPEAS(22.94)S(8.76)PPAS(-8.76)PLQHLLPGK 7 3 710.00071 0.004618 1325100 439240 0 0 885890 0 0 0 2093 1474 683 683 61 72;73 576 369 Mix4_TiO2_Reinj_1_3 7126 576 369 Mix4_TiO2_Reinj_1_3 7126 Q96TA1 Q96TA1 Q96TA1 >sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=2 0.999717 32.9463 0.999224 28.4964 0.138359 46.718 0 0 0.999717 32.9463 0.00903433 70.074 0 0 0 0 2 S ASSPPASPLQHLL CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00903433 70.074 _AAPEApSSPPApSPLQHLLPGK_ AAPEAS(0.559)S(0.442)PPAS(1)PLQHLLPGK AAPEAS(1.02)S(-1.02)PPAS(32.95)PLQHLLPGK 11 2 1064.4974 0.4965 1314400 220900 0 0 1093500 0 0 0 2094 1474 652 652 2311 2614 21396 13119 Mix4_InSol_Tio2_Reinj_1 7605 21396 13119 Mix4_InSol_Tio2_Reinj_1 7605 Q96TA1 Q96TA1 Q96TA1 >sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=2 0.999994 52.1013 0 0 0.999985 48.1278 0.492492 51.843 0.999994 52.1013 0.0524309 61.014 1 S QGLRPESPPPAGP CAMK2;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 0.0524309 61.014 _GLLAQGLRPEpSPPPAGPLLNGAPAGESPQPK_ GLLAQGLRPES(1)PPPAGPLLNGAPAGESPQPK GLLAQGLRPES(52.1)PPPAGPLLNGAPAGES(-52.1)PQPK 11 3 1032.8674 -1.3787 448530 0 0 0 0 0 219360 229170 2095 1474 628 628 4785 5435 45662 27926 Mix4_TiO2_1_5 7226 45663 27927 Mix4_TiO2_Reinj_1_3 8116 Q96TA1 Q96TA1 Q96TA1 >sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=2 0.431004 0 0.431004 0 0.00162489 79.345 0.0283422 -15.3206 4.0029E-13 134.15 1 S FEASPESPPPASP CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 4.0029E-13 134.15 _QVVSVVQDEEVGLPFEASPEpSPPPASPDGVTEIR_ QVVS(0.002)VVQDEEVGLPFEAS(0.102)PES(0.431)PPPAS(0.431)PDGVT(0.034)EIR QVVS(-23.84)VVQDEEVGLPFEAS(-6.25)PES(0)PPPAS(0)PDGVT(-11.03)EIR 21 3 1214.5801 0.049092 0 0 0 0 0 0 0 0 2096 1474 633 633 4785 5435 45663 27927 Mix4_TiO2_Reinj_1_3 8116 45663 27927 Mix4_TiO2_Reinj_1_3 8116 Q96TA1 Q96TA1 Q96TA1 >sp|Q96TA1|NIBL1_HUMAN Niban-like protein 1 OS=Homo sapiens GN=FAM129B PE=1 SV=2 0.96493 15.3206 0.938828 13.0756 0.00162489 79.345 0.96493 15.3206 4.0029E-13 134.15 1 S ESPPPASPDGVTE ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.0029E-13 134.15 _QVVSVVQDEEVGLPFEASPESPPPApSPDGVTEIR_ QVVSVVQDEEVGLPFEASPES(0.028)PPPAS(0.965)PDGVT(0.007)EIR QVVS(-110.09)VVQDEEVGLPFEAS(-43.43)PES(-15.32)PPPAS(15.32)PDGVT(-21.59)EIR 26 3 1214.5801 -0.05455 1580100 47058 0 0 1533100 0 0 0 2097 1475 46 46 5644 6430 55112 33724 Mix4_TiO2_1_4 4741 55110 33722 Mix4_InSol_TiO2_1 5753 Q96TC7 Q96TC7 Q96TC7 >sp|Q96TC7|RMD3_HUMAN Regulator of microtubule dynamics protein 3 OS=Homo sapiens GN=FAM82A2 PE=1 SV=2 0.981852 18.2294 0.981852 18.2294 3.96058E-06 106.98 0 0 0.928855 11.1591 1.71659E-15 146.92 0.904628 9.77503 4.79762E-21 165.67 0.92897 11.1767 1.23156E-15 149.66 1 S RHGRSQSLPNSLD 14-3-3 binding;CAMK2;GSK3 0.0001701 4.79762E-21 165.67 _SQpSLPNSLDYTQTSDPGR_ S(0.015)QS(0.982)LPNS(0.003)LDYTQTSDPGR S(-18.23)QS(18.23)LPNS(-24.62)LDY(-80.62)T(-62.79)QT(-101.59)S(-106.98)DPGR 3 2 1023.4442 0.79988 1904200 327890 0 0 1122700 0 252610 200970 2098 1476 558 558 6247 7137 61996 37553 Mix4_TiO2_1_3 2932 61996 37553 Mix4_TiO2_1_3 2932 Q99081;Q99081-2 Q99081 Q99081 >sp|Q99081|HTF4_HUMAN Transcription factor 12 OS=Homo sapiens GN=TCF12 PE=1 SV=1;>sp|Q99081-2|HTF4_HUMAN Isoform 2 of Transcription factor 12 OS=Homo sapiens GN=TCF12 0.364044 0 0.364044 0 0.000515018 95.972 1 S SSRGRTSSTNEDE PKA 0.042 0.000515018 95.972 _TpSSTNEDEDLNPEQK_ T(0.271)S(0.364)S(0.364)T(0.001)NEDEDLNPEQK T(-1.28)S(0)S(0)T(-27.66)NEDEDLNPEQK 2 2 893.85438 -0.80626 0 0 0 0 0 0 0 0 2099 1476 559 559 6247 7137 61996 37553 Mix4_TiO2_1_3 2932 61996 37553 Mix4_TiO2_1_3 2932 Q99081;Q99081-2 Q99081 Q99081 >sp|Q99081|HTF4_HUMAN Transcription factor 12 OS=Homo sapiens GN=TCF12 PE=1 SV=1;>sp|Q99081-2|HTF4_HUMAN Isoform 2 of Transcription factor 12 OS=Homo sapiens GN=TCF12 0.364044 0 0.364044 0 0.000515018 95.972 1 S SRGRTSSTNEDED CAMK2;CK2;PKA/AKT 0.001764 0.000515018 95.972 _TpSSTNEDEDLNPEQK_ T(0.271)S(0.364)S(0.364)T(0.001)NEDEDLNPEQK T(-1.28)S(0)S(0)T(-27.66)NEDEDLNPEQK 3 2 893.85438 -0.80626 0 0 0 0 0 0 0 0 2100 1479 315 315 6236 7124 61842 37465 Mix4_TiO2_1_5 3378 61842 37465 Mix4_TiO2_1_5 3378 Q99460;Q99460-2 Q99460 Q99460 >sp|Q99460|PSMD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens GN=PSMD1 PE=1 SV=2;>sp|Q99460-2|PSMD1_HUMAN Isoform 2 of 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens GN=PSMD1 0.999955 51.2951 0.999955 51.2951 0.0859856 51.295 2 S GKTPEASPEPKDQ CK1;Proline-directed 0.05 0.0859856 51.295 _TSSAFVGKpTPEApSPEPK_ TSSAFVGKT(0.999)PEAS(1)PEPK T(-42.72)S(-36.43)S(-36.43)AFVGKT(36.43)PEAS(51.3)PEPK 13 2 946.90757 -0.21382 18626 18626 0 0 0 0 0 0 2101 1480 825 825 5342 6083 51874 31755 Mix4_TiO2_Reinj_1_3 5483 51874 31755 Mix4_TiO2_Reinj_1_3 5483 Q99523 Q99523 Q99523 >sp|Q99523|SORT_HUMAN Sortilin OS=Homo sapiens GN=SORT1 PE=1 SV=3 0.88843 9.49092 0.80991 7.7144 0.136586 38.168 0 0 0.88843 9.49092 0.0145014 67.911 0 0 0.668922 6.06475 0.857845 6.0648 1 S SGYHDDSDEDLLE CK2 0.117 0.0145014 67.911 _SGYHDDpSDEDLLE_ S(0.012)GY(0.1)HDDS(0.888)DEDLLE S(-18.81)GY(-9.49)HDDS(9.49)DEDLLE 7 2 787.78015 -0.00070494 798440 213870 0 0 564170 0 0 20405 2102 1481 517 517 1462 1644 13687 8360 Mix4_TiO2_1_3 3921 13687 8360 Mix4_TiO2_1_3 3921 Q99567 Q99567 Q99567 >sp|Q99567|NUP88_HUMAN Nuclear pore complex protein Nup88 OS=Homo sapiens GN=NUP88 PE=1 SV=2 1 115.863 1 115.863 0.0031238 115.86 0 0 1 S DVEVAESPLRVLA CDK1;CDK2;Proline-directed 0.0057 0.0031238 115.86 _EDVEVAEpSPLR_ EDVEVAES(1)PLR EDVEVAES(115.86)PLR 8 2 662.29504 0.73169 80896 80896 0 0 0 0 0 0 2103 1481 35 35 4277 4867 40682 25032 Mix4_TiO2_Reinj_1_3 6055 40682 25032 Mix4_TiO2_Reinj_1_3 6055 Q99567 Q99567 Q99567 >sp|Q99567|NUP88_HUMAN Nuclear pore complex protein Nup88 OS=Homo sapiens GN=NUP88 PE=1 SV=2 0.966182 14.5956 0 0 0.966182 14.5956 4.18933E-09 117.91 1 S EGLKNQSPTEAEK CK2;Proline-directed 0.05 4.18933E-09 117.91 _NQpSPTEAEKPASSSLPSSPPPQLLTR_ NQS(0.966)PT(0.034)EAEKPASSSLPSSPPPQLLTR NQS(14.6)PT(-14.6)EAEKPAS(-35.64)S(-49.91)S(-49.91)LPS(-97.95)S(-107.96)PPPQLLT(-117.91)R 3 3 933.7902 -0.26207 326930 0 0 0 326930 0 0 0 2104 1482 273 273 77 91;92 887 590 Mix4_TiO2_Reinj_1_5 4160 887 590 Mix4_TiO2_Reinj_1_5 4160 Q99569;Q99569-2 Q99569 Q99569 >sp|Q99569|PKP4_HUMAN Plakophilin-4 OS=Homo sapiens GN=PKP4 PE=1 SV=1;>sp|Q99569-2|PKP4_HUMAN Isoform Short of Plakophilin-4 OS=Homo sapiens GN=PKP4 0.949589 13.2718 0.846256 8.23081 0.125789 44.801 0.949589 13.2718 0.00384757 78.363 2 S PAARAASPYSQRP CAMK2;Proline-directed 0.042 0.00384757 78.363 _AApSPYSQRPApSPTAIR_ AAS(0.95)PY(0.046)S(0.008)QRPAS(0.988)PT(0.008)AIR AAS(13.27)PY(-13.27)S(-23.09)QRPAS(21.3)PT(-21.3)AIR 3 2 916.90824 -0.15958 241250 57179 0 0 184070 0 0 0 2105 1482 281 281 77 91;92 887 590 Mix4_TiO2_Reinj_1_5 4160 887 590 Mix4_TiO2_Reinj_1_5 4160 Q99569;Q99569-2 Q99569 Q99569 >sp|Q99569|PKP4_HUMAN Plakophilin-4 OS=Homo sapiens GN=PKP4 PE=1 SV=1;>sp|Q99569-2|PKP4_HUMAN Isoform Short of Plakophilin-4 OS=Homo sapiens GN=PKP4 0.987816 21.297 0.977332 18.8732 0.125789 44.801 0.987816 21.297 0.00384757 78.363 2 S YSQRPASPTAIRR CAMK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00384757 78.363 _AApSPYSQRPApSPTAIR_ AAS(0.95)PY(0.046)S(0.008)QRPAS(0.988)PT(0.008)AIR AAS(13.27)PY(-13.27)S(-23.09)QRPAS(21.3)PT(-21.3)AIR 11 2 916.90824 -0.15958 241250 57179 0 0 184070 0 0 0 2106 1482 75 75 3427 3871 32180 19886 Mix4_TiO2_Reinj_1_5 3997 32180 19886 Mix4_TiO2_Reinj_1_5 3997 Q99569;Q99569-2 Q99569 Q99569 >sp|Q99569|PKP4_HUMAN Plakophilin-4 OS=Homo sapiens GN=PKP4 PE=1 SV=1;>sp|Q99569-2|PKP4_HUMAN Isoform Short of Plakophilin-4 OS=Homo sapiens GN=PKP4 0.786379 5.66197 0 0 0.786379 5.66197 0.118959 45.85 1 S CRLGAESPSIAST Proline-directed 0.05 0.118959 45.85 _LGAEpSPSIASTSSTEK_ LGAES(0.786)PS(0.214)IASTSSTEK LGAES(5.66)PS(-5.66)IAS(-45.85)T(-45.85)S(-45.85)S(-45.85)T(-45.85)EK 5 2 822.87184 0.011657 95294 0 0 0 95294 0 0 0 2107 1482 335 335 6347;6348 7257;7258;7259 64012 39235 Mix4_InSol_Tio2_Reinj_1 2688 64011 39234 Mix4_InSol_TiO2_1 2678 Q99569;Q99569-2 Q99569 Q99569 >sp|Q99569|PKP4_HUMAN Plakophilin-4 OS=Homo sapiens GN=PKP4 PE=1 SV=1;>sp|Q99569-2|PKP4_HUMAN Isoform Short of Plakophilin-4 OS=Homo sapiens GN=PKP4 0.574864 6.13591 0.439077 0 0.132434 43.804 0.428483 1.90079 0.0850557 49.413 0.519084 3.77959 0.0347481 58.469 0.574864 6.13591 0.131363 43.944 1 S SQGQVGSSSPKRS 0.0347481 58.469 _VASPSQGQVGpSSSPK_ VAS(0.073)PS(0.073)QGQVGS(0.575)S(0.14)S(0.14)PK VAS(-8.99)PS(-8.99)QGQVGS(6.14)S(-6.14)S(-6.14)PK 11 2 748.34305 2.2499 107110 0 0 0 0 0 90481 16631 2108 1482 337 337 6347;6348 7257;7258;7259 64011 39234 Mix4_InSol_TiO2_1 2678 64011 39234 Mix4_InSol_TiO2_1 2678 Q99569;Q99569-2 Q99569 Q99569 >sp|Q99569|PKP4_HUMAN Plakophilin-4 OS=Homo sapiens GN=PKP4 PE=1 SV=1;>sp|Q99569-2|PKP4_HUMAN Isoform Short of Plakophilin-4 OS=Homo sapiens GN=PKP4 0.973042 18.5852 0.70536 6.5945 0.132434 43.804 0.718567 7.08477 0.0850557 49.413 0.973042 18.5852 0.0347481 58.469 0.78029 5.78488 0.131363 43.944 1 S GQVGSSSPKRSGM CDK1;CDK2;GSK3;Polo box;Proline-directed 0.00405 0.0347481 58.469 _VASPSQGQVGSSpSPK_ VASPSQGQVGS(0.013)S(0.013)S(0.973)PK VAS(-58.47)PS(-58.47)QGQVGS(-18.59)S(-18.59)S(18.59)PK 13 2 748.34305 1.9342 467920 70414 0 0 292510 0 21038 83961 2109 1482 314 314 6420 7344 64827 39779 Mix4_InSol_TiO2_1 5800 64833 39785 Mix4_TiO2_Reinj_1_5 5484 Q99569;Q99569-2 Q99569 Q99569 >sp|Q99569|PKP4_HUMAN Plakophilin-4 OS=Homo sapiens GN=PKP4 PE=1 SV=1;>sp|Q99569-2|PKP4_HUMAN Isoform Short of Plakophilin-4 OS=Homo sapiens GN=PKP4 1 67.5803 0.999027 34.8845 0.189648 34.884 0.999968 44.9489 0.00843153 75.122 1 63.7245 3.35514E-05 125.52 0 0 1 67.5803 0.000434432 104.92 0.999997 56.0247 0.0107174 72.407 1 S TTARVGSPLTLTD CAMK2;ERK/MAPK;Proline-directed 0.0034 3.35514E-05 125.52 _VGpSPLTLTDAQTR_ VGS(1)PLTLTDAQTR VGS(67.58)PLT(-67.58)LT(-96.47)DAQT(-104.92)R 3 2 719.85051 0.19924 833060 49138 30558 0 470090 0 167050 116220 2110 1484 39 39 4674 5305 44327 27116 Mix4_TiO2_1_5 4583 44328 27117 Mix4_TiO2_1_5 4642 Q99613 Q99613 Q99613 >sp|Q99613|EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens GN=EIF3C PE=1 SV=1 0.999879 39.1738 0.999879 39.1738 0.100738 41.956 0 0 0.999808 37.1612 0.181115 37.161 0.996426 24.4525 0.434332 24.453 0.997611 26.2066 0.399316 26.207 1 S KQPLLLSEDEEDT CK2;NEK6 0.076 0.100738 41.956 _QPLLLpSEDEEDTKR_ QPLLLS(1)EDEEDTKR QPLLLS(39.17)EDEEDT(-39.17)KR 6 2 876.90621 0.59242 1680700 380500 0 0 1036300 0 155130 108790 2111 1485 151 151 2023 2293 18532 11223 Mix4_TiO2_1_2 4588 18532 11223 Mix4_TiO2_1_2 4588 Q99623 Q99623 Q99623 >sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=PHB2 PE=1 SV=2 0.999973 45.6867 0.999973 45.6867 0.0509493 45.687 0 0 1 S VAKFNASQLITQR 0.0509493 45.687 _FNApSQLITQR_ FNAS(1)QLITQR FNAS(45.69)QLIT(-45.69)QR 4 2 629.303 0.60076 14673 0.049253 14673 0 0 0 0 0 0 2112 1486 469 469 728;729 833;834 7019 4168 Mix4_TiO2_Reinj_1_3 6589 7017 4163 Mix4_TiO2_1_4 5818 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 1 83.3184 1 73.2966 1.06061E-15 182.39 0 0 1 83.3184 3.85769E-05 114.9 5.00111E-08 -69.999 0.00940299 69.999 8.29912E-08 -67.7991 0.0110379 68.218 1 S RDALDLSDINSEP GSK3;NEK6 0.076 1.06061E-15 182.39 _DALDLpSDINSEPPR_ DALDLS(1)DINSEPPR DALDLS(83.32)DINS(-83.32)EPPR 6 2 811.3589 0.77389 1483200 211630 0 0 1271500 0 0 0 2113 1486 479 479 729;2433 834;2759 7031 4180 Mix4_TiO2_1_4 7093 7031 4180 Mix4_TiO2_1_4 7093 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 0.998473 28.1559 0.998473 28.1559 3.85618E-17 140.08 0 0 0.988295 20.7388 9.08167E-07 100.26 0.499999 0 0.00940299 69.999 0.499965 0 0.0110379 68.218 1 S SEPPRGSFPSFEP AURORA;PKA 0.038874 3.85618E-17 140.08 _DALDLSDINSEPPRGpSFPSFEPR_ DALDLSDINSEPPRGS(0.998)FPS(0.002)FEPR DALDLS(-126.53)DINS(-65.28)EPPRGS(28.16)FPS(-28.16)FEPR 16 3 876.06555 -0.16379 4440000 596.89 1127900 0 0 2883700 0 231550 196840 2114 1486 482 482 729;2433 834;2759 22838 14271 Mix4_TiO2_Reinj_1_4 6269 7031 4180 Mix4_TiO2_1_4 7093 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 0.999921 41.015 0.499091 0 3.85618E-17 140.08 0 0 0.999921 41.015 9.08167E-07 100.26 0.499999 0 0.00940299 69.999 0.499965 0 0.0110379 68.218 1 S PRGSFPSFEPRNL CK1 0.081 3.85618E-17 140.08 _GSFPpSFEPR_ GSFPS(1)FEPR GS(-41.02)FPS(41.02)FEPR 5 2 552.23151 -0.099065 518420 69.694 0 0 0 90023 0 231550 196840 2115 1486 143 143 5492;5493 6252;6253;6254;6255 53661 32805 Mix4_InSol_Tio2_Reinj_1 4609 53658 32802 Mix4_InSol_TiO2_1 4723 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 0.99878 29.1303 0.985251 18.2477 0.44163 18.248 0.932655 11.4141 0.645433 11.414 0.91817 10.5001 0.672693 10.5 0.998754 29.0385 0.0995772 38.79 0.99878 29.1303 0.159704 34.501 1 S AVKRSMSPFRGPK CAMK2;CDK1;CDK2;CHK1;PKA;PKD;Proline-directed 0.003024 0.0995772 38.79 _SMpSPFRGPK_ S(0.001)MS(0.999)PFRGPK S(-29.13)MS(29.13)PFRGPK 3 2 543.74373 -0.3678 5270700 272750 11785 0 1381800 0 1968200 1636100 2116 1486 452 452 6281 7176 62792 38227 Mix4_TiO2_Reinj_1_4 2114 62784 38204 Mix4_TiO2_1_4 1188 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 0.642963 8.57533 0.0326183 -11.3883 0.00171487 91.715 0.0574493 -8.57533 0.00622438 65.609 0.642963 8.57533 0.0236317 55.403 0.00132607 -25.7217 0.0696249 40.926 0.00026383 -35.475 0.031459 52.925 1 S LARTVGSTSTPRS 0.00171487 91.715 _TVGpSTSTPR_ T(0.089)VGS(0.643)T(0.089)S(0.089)T(0.089)PR T(-8.58)VGS(8.58)T(-8.58)S(-8.58)T(-8.58)PR 4 2 493.22115 0.68762 0 0 0 0 0 0 0 0 2117 1486 454 454 6281 7176 62789 38220 Mix4_TiO2_Reinj_1_3 1655 62784 38204 Mix4_TiO2_1_4 1188 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 0.925043 11.4382 0.827674 9.14953 0.00171487 91.715 0.849767 10.2958 0.00622438 65.609 0.925043 11.4382 0.0236317 55.403 0.49515 0 0.0696249 40.926 0.108148 -9.16129 0.031459 52.925 1 S RTVGSTSTPRSRC GSK3 0.081 0.00171487 91.715 _TVGSTpSTPR_ TVGST(0.008)S(0.925)T(0.066)PR T(-48.68)VGS(-46.8)T(-20.37)S(11.44)T(-11.44)PR 6 2 493.22115 0.17197 3849400 20345 193500 0 3635600 0 0 0 2118 1487 1029 1029 6062 6915;6916 59844 36299 Mix4_TiO2_1_5 7275 59844 36299 Mix4_TiO2_1_5 7275 Q99683 Q99683 Q99683 >sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 OS=Homo sapiens GN=MAP3K5 PE=1 SV=1 0.999996 54.0742 0.999996 54.0742 0.0957438 54.074 0.00156189 -28.0567 0.0379774 58.69 2 S ENFEDHSAPPSPE GSK3 0.081 0.0957438 54.074 _TLFLGIPDENFEDHpSAPPpSPEEK_ TLFLGIPDENFEDHS(1)APPS(1)PEEK T(-54.07)LFLGIPDENFEDHS(54.07)APPS(54.07)PEEK 15 3 910.3855 0.22531 79170 79170 0 0 0 0 0 0 2119 1487 1033 1033 6062 6915;6916 59842 36297 Mix4_TiO2_Reinj_1_5 7825 59842 36297 Mix4_TiO2_Reinj_1_5 7825 Q99683 Q99683 Q99683 >sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 OS=Homo sapiens GN=MAP3K5 PE=1 SV=1 0.998437 28.0567 0.997167 25.49 0.171543 48.018 0.998437 28.0567 0.0379774 58.69 1 S DHSAPPSPEEKDS CK1;CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0379774 58.69 _TLFLGIPDENFEDHSAPPpSPEEK_ TLFLGIPDENFEDHS(0.002)APPS(0.998)PEEK T(-58.69)LFLGIPDENFEDHS(-28.06)APPS(28.06)PEEK 19 3 883.73006 0.25816 1012900 198340 0 0 814540 0 0 0 2120 1488 2124 2124 3766 4250 35629 22020 Mix4_TiO2_Reinj_1_1 4333 35629 22020 Mix4_TiO2_Reinj_1_1 4333 Q99698 Q99698 Q99698 >sp|Q99698|LYST_HUMAN Lysosomal-trafficking regulator OS=Homo sapiens GN=LYST PE=1 SV=3 0.99805 27.1187 0.99805 27.1187 0.0299845 49.241 1 S SQKLTGSLGCSID GSK3;NEK6 0.076 0.0299845 49.241 _LTGpSLGCSIDR_ LT(0.002)GS(0.998)LGCSIDR LT(-27.12)GS(27.12)LGCS(-49.24)IDR 4 2 629.7785 -0.085291 0 0 0 0 0 0 0 0 2121 1488 2105 2105 5680 6468 55655 34102 Mix4_TiO2_Reinj_1_1 6628 55655 34102 Mix4_TiO2_Reinj_1_1 6628 Q99698 Q99698 Q99698 >sp|Q99698|LYST_HUMAN Lysosomal-trafficking regulator OS=Homo sapiens GN=LYST PE=1 SV=3 0.817127 6.50624 0.807946 8.0243 0.743013 23.726 0.817127 6.50624 0.00796694 73.916 1 S HMLRSRSLPAFPT 14-3-3 binding;CAMK2;CHK1 0.0001701 0.00796694 73.916 _SRpSLPAFPTSSLLTQSQK_ S(0.183)RS(0.817)LPAFPTSSLLTQSQK S(-6.51)RS(6.51)LPAFPT(-36.07)S(-59.76)S(-59.12)LLT(-73.03)QS(-73.92)QK 3 3 676.6769 -0.044127 166960 35036 0 0 131930 0 0 0 2122 1489 743 743 629 724 5980 3504 Mix4_TiO2_1_3 1269 5982 3508 Mix4_TiO2_Reinj_1_3 1878 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.368134 0 0.368134 0 0.578193 13.669 0.0295557 -15.029 0.222527 30.02 0.154735 -7.28341 0.0389634 50.549 0 0 0 0 1 S NRAVTPSSEAKDS 0.0389634 50.549 _AVTPpSSEAK_ AVT(0.264)PS(0.368)S(0.368)EAK AVT(-1.45)PS(0)S(0)EAK 5 2 485.21807 -0.34621 0 0 0 0 0 0 0 0 2123 1489 744 744 629 724 5980 3504 Mix4_TiO2_1_3 1269 5982 3508 Mix4_TiO2_Reinj_1_3 1878 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.368134 0 0.368134 0 0.578193 13.669 0.0295557 -15.029 0.222527 30.02 0.0174602 -16.7588 0.0389634 50.549 0 0 0 0 1 S RAVTPSSEAKDSR 0.0389634 50.549 _AVTPpSSEAK_ AVT(0.264)PS(0.368)S(0.368)EAK AVT(-1.45)PS(0)S(0)EAK 6 2 485.21807 -0.34621 0 0 0 0 0 0 0 0 2124 1489 776 776 1701 1912 15548 9377 Mix4_TiO2_Reinj_1_5 3892 15547 9376 Mix4_TiO2_1_5 3261 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.384213 0.988981 0.000305153 -34.1093 0.0431301 55.639 0.384213 0.988981 0.0801739 46.84 1 S ETSPSFSKAENKG CK1;CK2 0.117 0.0431301 55.639 _ENIKPNETSPSFpSK_ ENIKPNET(0.004)S(0.306)PS(0.306)FS(0.384)K ENIKPNET(-19.99)S(-0.99)PS(-0.99)FS(0.99)K 13 3 553.25382 0.31485 0 0 0 0 0 0 0 0 2125 1489 784 784 2285 2583 21043 12884 Mix4_TiO2_1_5 3194 21043 12884 Mix4_TiO2_1_5 3194 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.99999 49.8989 0.99999 49.8989 0.0382284 49.899 0 0 0.999826 37.6004 0.105697 37.6 1 S AENKGISPVVSEH GSK3;Proline-directed 0.05 0.0382284 49.899 _GIpSPVVSEHR_ GIS(1)PVVSEHR GIS(49.9)PVVS(-49.9)EHR 3 2 580.77662 0.43683 256420 39666 0 0 216750 0 0 0 2126 1489 624 624 3906 4445 37025 22775 Mix4_InSol_TiO2_1 3924 37025 22775 Mix4_InSol_TiO2_1 3924 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.999753 39.0769 0.999753 39.0769 0.108451 39.077 0.98617 21.5415 0.3263 21.542 1 S EGPPRMSPKAQRH CDK1;PKA;Proline-directed 0.0057 0.108451 39.077 _MSSEGPPRMpSPK_ MSSEGPPRMS(1)PK MS(-39.08)S(-39.08)EGPPRMS(39.08)PK 10 2 692.29346 -0.030504 118890 0 0 0 0 0 73114 45772 2127 1489 667 667 6227 7113 61661 37371 Mix4_TiO2_1_5 6020 61661 37371 Mix4_TiO2_1_5 6020 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.355145 0 0.355145 0 0.139268 43.569 1 S PPVARTSPSGGTW PKA;Proline-directed 0.042 0.139268 43.569 _TpSPSGGTWSSVVSGVPR_ T(0.276)S(0.355)PS(0.355)GGT(0.014)WSSVVSGVPR T(-1.1)S(0)PS(0)GGT(-14.04)WS(-34.93)S(-40.97)VVS(-43.57)GVPR 2 2 870.90127 0.059247 0 0 0 0 0 0 0 0 2128 1489 669 669 6227 7113 61661 37371 Mix4_TiO2_1_5 6020 61661 37371 Mix4_TiO2_1_5 6020 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.355145 0 0.355145 0 0.139268 43.569 1 S VARTSPSGGTWSS 0.139268 43.569 _TpSPSGGTWSSVVSGVPR_ T(0.276)S(0.355)PS(0.355)GGT(0.014)WSSVVSGVPR T(-1.1)S(0)PS(0)GGT(-14.04)WS(-34.93)S(-40.97)VVS(-43.57)GVPR 4 2 870.90127 0.059247 0 0 0 0 0 0 0 0 2129 1489 466 466 6337 7246 63877 39135 Mix4_TiO2_Reinj_1_5 4553 63877 39135 Mix4_TiO2_Reinj_1_5 4553 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.99996 44.2847 0 0 0.99996 44.2847 0.0451689 57.224 1 S LENDDRSEEEKYT CK2 0.117 0.0451689 57.224 _VALENDDRpSEEEKYTAVQR_ VALENDDRS(1)EEEKYTAVQR VALENDDRS(44.28)EEEKY(-44.28)T(-56.01)AVQR 9 3 778.01994 -0.61687 196750 0 0 0 196750 0 0 0 2130 1492 281 281 451 513 4196 2506 Mix4_TiO2_Reinj_1_3 2923 4193 2502 Mix4_TiO2_1_3 2394 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 1 35.3523 1 12.3861 0.0304487 58.91 1 35.3523 0.24492 35.352 1 S RMSRAQSFPDNRQ CAMK2;CHK1;CK1;CK2 0.0228 0.0304487 58.91 _AQpSFPDNR_ AQS(1)FPDNR AQS(35.35)FPDNR 3 2 507.70566 1.2363 967450 346390 0 0 621060 0 0 0 2131 1492 176 176 519;2808 585;3199 4792 2889 Mix4_TiO2_Reinj_1_3 5675 4792 2889 Mix4_TiO2_Reinj_1_3 5675 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.605058 1.85264 0.5 0 8.54387E-21 157.63 0.605058 1.85264 9.25962E-26 182.12 0.516474 0.683488 0.105981 50.369 0.198866 -6.03182 0.0114094 67.375 1 S QVRIKASQSAGDI 9.25962E-26 182.12 _ApSQSAGDINTIYQPPEPR_ AS(0.605)QS(0.395)AGDINTIYQPPEPR AS(1.85)QS(-1.85)AGDINT(-90.1)IY(-153.59)QPPEPR 2 2 1012.4597 0.078143 1562400 319550 0 0 938180 0 304620 0 2132 1492 178 178 519;2808 585;3199 26881 16796 Mix4_InSol_Tio2_Reinj_1 5955 4792 2889 Mix4_TiO2_Reinj_1_3 5675 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.797523 6.03182 0.5 0 8.54387E-21 157.63 0.412692 0 9.25962E-26 182.12 0.499988 0 0.105981 50.369 0.797523 6.03182 0.0114094 67.375 1 S RIKASQSAGDINT CK2 0.117 9.25962E-26 182.12 _IKASQpSAGDINTIYQPPEPR_ IKAS(0.199)QS(0.798)AGDINT(0.004)IYQPPEPR IKAS(-6.03)QS(6.03)AGDINT(-23.44)IY(-59.55)QPPEPR 6 3 755.70189 -0.081269 536600 319550 0 0 0 0 52196 164850 2133 1492 197 197 2622;2623 2984;2985;2986 24493 15196 Mix4_TiO2_1_3 2439 24498 15201 Mix4_TiO2_1_3 3915 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.999371 32.6919 0.999371 32.6919 5.65712E-07 106.96 0.994453 24.8913 9.59904E-07 99.197 0 0 0.762997 7.78617 0.00668185 72.676 1 S PRSRHLSVSSQNP CAMK2;CK1;PIM1/2;PKA/AKT 0.000138852 5.65712E-07 106.96 _HLpSVSSQNPGR_ HLS(0.999)VS(0.001)SQNPGR HLS(32.69)VS(-32.69)S(-40.39)QNPGR 3 2 631.28788 0.12153 2036400 342020 0 0 1694400 0 0 0 2134 1492 206 206 2623;5725 2985;2986;6525 24496 15199 Mix4_InSol_Tio2_Reinj_1 4766 24498 15201 Mix4_TiO2_1_3 3915 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.499876 0 0.443697 -0.935368 5.65712E-07 106.96 0 0 0.495265 0 9.59904E-07 99.197 0 0 0.499876 0 0.013584 64.881 1 S SQNPGRSSPPPGY 5.65712E-07 106.96 _HLSVSSQNPGRpSSPPPGYVPER_ HLSVSSQNPGRS(0.5)S(0.5)PPPGYVPER HLS(-55.16)VS(-37.32)S(-36.32)QNPGRS(0)S(0)PPPGY(-41.19)VPER 12 3 810.05169 -0.33024 0 0 0 0 0 0 0 0 2135 1492 207 207 2623;5725 2985;2986;6525 24499 15204 Mix4_TiO2_1_4 3976 24498 15201 Mix4_TiO2_1_3 3915 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.875183 8.46594 0.875183 8.46594 5.65712E-07 106.96 0 0 0.814329 6.4217 9.59904E-07 99.197 0 0 0.761376 6.82244 0.013584 64.881 1 S QNPGRSSPPPGYV PKA;Polo box;Proline-directed 0.00405 5.65712E-07 106.96 _HLSVSSQNPGRSpSPPPGYVPER_ HLSVSSQNPGRS(0.125)S(0.875)PPPGYVPER HLS(-55.76)VS(-38.11)S(-40.87)QNPGRS(-8.47)S(8.47)PPPGY(-48.47)VPER 13 3 810.05169 0.73244 8763100 1473900 0 0 7244500 0 0 44658 2136 1492 368 368 3701;5086 4173;4174;5785 34862 21626 Mix4_TiO2_1_3 3539 34855 21619 Mix4_InSol_TiO2_1 4557 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.999298 31.5355 0.999298 31.5355 2.70748E-12 171.7 0 0 0.999983 47.5859 4.0116E-07 126.48 0.521831 0.410147 1.13762E-16 191.57 0.916884 10.4569 3.4076E-09 142.11 1 S PRGRLRSADSENA CAMK2;PKA/AKT 0.001764 1.13762E-16 191.57 _LRpSADSENALSVQER_ LRS(0.999)ADS(0.001)ENALSVQER LRS(31.54)ADS(-31.54)ENALS(-115.61)VQER 3 2 877.90708 0.80639 1816200 119.66 595720 0 0 1185600 0 19883 14974 2137 1492 371 371 3701;5086 4173;4174;5785 34855 21619 Mix4_InSol_TiO2_1 4557 34855 21619 Mix4_InSol_TiO2_1 4557 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.994247 22.376 0.984278 17.9661 2.70748E-12 171.7 0 0 0.882117 8.74075 1.0223E-05 135.39 0.994247 22.376 1.13762E-16 191.57 0.988977 19.5288 3.4076E-09 142.11 1 S RLRSADSENALSV CK1 0.081 1.13762E-16 191.57 _LRSADpSENALSVQER_ LRS(0.006)ADS(0.994)ENALSVQER LRS(-22.38)ADS(22.38)ENALS(-66.49)VQER 6 2 877.90708 0.2658 5447000 358.87 1095800 0 0 3463700 0 351940 535480 2138 1492 160 160 4065 4632 38549 23648 Mix4_InSol_TiO2_1 1496 38551 23650 Mix4_TiO2_Reinj_1_3 1203 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.569054 2.83552 0.0130636 -18.7243 2.74154E-09 170.13 0.569054 2.83552 0.700256 11.451 0.238906 0 0.976728 1.6474 1 S QDRNHNSSSPHSG 2.74154E-09 170.13 _NHNpSSSPHSGVSR_ NHNS(0.569)S(0.296)S(0.053)PHS(0.041)GVS(0.041)R NHNS(2.84)S(-2.84)S(-10.29)PHS(-11.45)GVS(-11.45)R 4 2 723.29951 0.2649 17728 0 0 0 0 0 17728 0 2139 1492 162 162 4065 4632 38552 23652 Mix4_TiO2_Reinj_1_3 1207 38551 23650 Mix4_TiO2_Reinj_1_3 1203 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.973861 18.7243 0.973861 18.7243 2.74154E-09 170.13 0.0532411 -10.2891 0.700256 11.451 0.195213 -0.877174 0.976728 1.6474 1 S RNHNSSSPHSGVS Polo box;Proline-directed 0.00405 2.74154E-09 170.13 _NHNSSpSPHSGVSR_ NHNS(0.013)S(0.013)S(0.974)PHSGVSR NHNS(-18.72)S(-18.72)S(18.72)PHS(-50.17)GVS(-55.96)R 6 3 482.53543 -0.18592 833200 0 0 0 833200 0 0 0 2140 1492 388 388 4374 4974 41467 25482 Mix4_TiO2_1_3 4786 41467 25482 Mix4_TiO2_1_3 4786 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.573158 1.39888 0.573158 1.39888 0.0132781 70.18 0 0 0 0 0.556743 1.2861 0.0959567 43.092 0 0 1 S VPTKSPSAPINWR CK1 0.143 0.0132781 70.18 _NVPTKSPpSAPINWR_ NVPT(0.012)KS(0.415)PS(0.573)APINWR NVPT(-16.97)KS(-1.4)PS(1.4)APINWR 8 2 823.90615 0.074498 291970 164030 0 0 0 0 127940 0 2141 1492 268 268 5087 5787 49219 30043 Mix4_TiO2_1_3 2526 49219 30043 Mix4_TiO2_1_3 2526 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.988447 19.3227 0.988447 19.3227 0.0159912 67.35 0.852304 7.61226 0.0218046 60.272 1 S LDRSADSPSFRKS CK1;Proline-directed 0.05 0.0159912 67.35 _SADpSPSFR_ SADS(0.988)PS(0.012)FR S(-61.46)ADS(19.32)PS(-19.32)FR 4 2 473.68694 0.31056 421480 84139 0 0 337340 0 0 0 2142 1492 347 347 5475 6231 53401 32626 Mix4_InSol_Tio2_Reinj_1 8340 53401 32626 Mix4_InSol_Tio2_Reinj_1 8340 Q99759-2;Q99759 Q99759-2 Q99759-2 >sp|Q99759-2|M3K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3;>sp|Q99759|M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2 0.548178 1.54322 0 0 0 0 0.544424 1.3094 7.05517E-05 97.694 0.548178 1.54322 3.62685E-11 136.12 1 S PSSRSLSTNGENM CAMK2;CK1 0.042 3.62685E-11 136.12 _SLpSTNGENMGLAVQYLDPR_ S(0.384)LS(0.548)T(0.068)NGENMGLAVQYLDPR S(-1.54)LS(1.54)T(-9.09)NGENMGLAVQY(-136.12)LDPR 3 2 1072.9877 0.43212 245300 0 0 0 0 0 148930 96373 2143 1494 254 254 3346 3785 31556 19533 Mix4_TiO2_Reinj_1_5 5277 31556 19533 Mix4_TiO2_Reinj_1_5 5277 Q99808 Q99808 Q99808 >sp|Q99808|S29A1_HUMAN Equilibrative nucleoside transporter 1 OS=Homo sapiens GN=SLC29A1 PE=1 SV=3 1 29.8242 1 24.8569 0.263955 24.857 1 29.8242 0.128932 29.824 0 0 0 0 1 S TKLDLISKGEEPR CK2 0.117 0.128932 29.824 _LDLIpSKGEEPR_ LDLIS(1)KGEEPR LDLIS(29.82)KGEEPR 5 2 668.82905 -0.18983 168740 29377 0 0 139360 0 0 0 2144 1497 135 135 2483 2822 23406 14564 Mix4_TiO2_1_3 2109 23406 14564 Mix4_TiO2_1_3 2109 Q99959;Q99959-2 Q99959 Q99959 >sp|Q99959|PKP2_HUMAN Plakophilin-2 OS=Homo sapiens GN=PKP2 PE=1 SV=2;>sp|Q99959-2|PKP2_HUMAN Isoform A of Plakophilin-2 OS=Homo sapiens GN=PKP2 0.969873 17.8369 0.969873 17.8369 0.109295 40.735 0 0 0 0 0 0 1 S QYSSQKSVEERSL CK1;CK2 0.081 0.109295 40.735 _GTAQYSSQKpSVEER_ GT(0.001)AQYS(0.016)S(0.013)QKS(0.97)VEER GT(-32.38)AQY(-35.3)S(-17.84)S(-18.62)QKS(17.84)VEER 10 2 825.36197 0.53578 13580 13580 0 0 0 0 0 0 2145 1499 674 674 6064;6065 6918;6919 59854 36305 Mix4_TiO2_1_5 2862 59854 36305 Mix4_TiO2_1_5 2862 Q9BPX3 Q9BPX3 Q9BPX3 >sp|Q9BPX3|CND3_HUMAN Condensin complex subunit 3 OS=Homo sapiens GN=NCAPG PE=1 SV=1 1 86.3812 1 86.3812 2.11788E-11 136.91 0.105039 -4.40931 2.15117 4.4093 0.998433 28.0755 3.52563E-12 129.21 0 0 0 0 1 S EGTEINSDDEQES CK1;CK2 0.117 2.11788E-11 136.91 _TLHCEGTEINpSDDEQESK_ TLHCEGTEINS(1)DDEQESK T(-123.57)LHCEGT(-117.23)EINS(86.38)DDEQES(-86.38)K 11 3 724.61934 -0.68231 3573300 733980 0 0 2839300 0 0 0 2146 1500 512 512 5055 5749 48870 29868 Mix4_TiO2_Reinj_1_3 4663 48870 29868 Mix4_TiO2_Reinj_1_3 4663 Q9BPZ7;Q9BPZ7-2;Q9BPZ7-3;Q9BPZ7-4 Q9BPZ7 Q9BPZ7 >sp|Q9BPZ7|SIN1_HUMAN Target of rapamycin complex 2 subunit MAPKAP1 OS=Homo sapiens GN=MAPKAP1 PE=1 SV=2;>sp|Q9BPZ7-2|SIN1_HUMAN Isoform beta of Target of rapamycin complex 2 subunit MAPKAP1 OS=Homo sapiens GN=MAPKAP1;>sp|Q9BPZ7-3|SIN1_HUMAN Isoform 3 of T 0.999858 38.5676 0.988986 20.4713 0.0962047 48.798 0.999858 38.5676 0.00532388 83.211 0 0 0 0 1 S NRRTSFSFQKEKK 0.00532388 83.211 _RTSFpSFQK_ RTSFS(1)FQK RT(-54.88)S(-38.57)FS(38.57)FQK 5 2 540.74733 0.048032 470940 89077 0 0 381870 0 0 0 2147 1503 439 439 1346 1516 12587 7697 Mix4_TiO2_Reinj_1_4 4966 12587 7697 Mix4_TiO2_Reinj_1_4 4966 Q9BQE3 Q9BQE3 Q9BQE3 >sp|Q9BQE3|TBA1C_HUMAN Tubulin alpha-1C chain OS=Homo sapiens GN=TUBA1C PE=1 SV=1 1 119.717 0 0 1 119.717 6.80218E-26 178.36 1 S EEVGADSADGEDE 6.80218E-26 178.36 _DYEEVGADpSADGEDEGEEY_ DYEEVGADS(1)ADGEDEGEEY DY(-119.72)EEVGADS(119.72)ADGEDEGEEY(-153.28) 9 2 1079.8602 0.66107 491200 0.0063553 0 0 0 491200 0 0 0 2148 1504 775 775 328 371 3032 1839 Mix4_TiO2_Reinj_1_6 7691 3032 1839 Mix4_TiO2_Reinj_1_6 7691 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.999999 62.0192 0.999999 62.0192 0.0419806 69.956 1 S ALGGEDSENEEEL CK2 0.117 0.0419806 69.956 _ALGGEDpSENEEELGDEAM(ox)M(ox)ALDQSLASLFAEQK_ ALGGEDS(1)ENEEELGDEAMMALDQSLASLFAEQK ALGGEDS(62.02)ENEEELGDEAMMALDQS(-62.02)LAS(-69.96)LFAEQK 7 3 1213.8461 -0.11074 206350 0 0 0 206350 0 0 0 2149 1504 1163 1163 727;1595;1596 832;1789;1790;1791 14683 8923 Mix4_TiO2_Reinj_1_5 3837 7011 4160 Mix4_InSol_TiO2_1 4132 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.999957 44.5671 0.998939 31.6808 0.000597183 109.19 0.98115 17.7955 0.0309504 56.341 0.999957 44.5671 1.08626E-05 141.79 0 0 0.991061 22.6879 2.26893E-09 146.99 0.981842 17.5732 0.0202655 59.366 1 S IPSATQSPISKKR CK1;Proline-directed 0.05 2.26893E-09 146.99 _EIPSATQpSPISK_ EIPSATQS(1)PISK EIPS(-78.25)AT(-44.57)QS(44.57)PIS(-50.84)K 8 2 669.32106 0.11252 5344700 961840 77647 0 2102300 0 1352700 850140 2150 1504 11 11 1094 1230 10320 6361 Mix4_TiO2_1_1 2017 10321 6362 Mix4_TiO2_Reinj_1_1 2376 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.999344 33.5625 0.999344 33.5625 0.015616 67.869 0.998673 28.7664 1.42769E-12 140.51 1 S DPAQPMSPGEATQ CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.42769E-12 140.51 _DPAQPM(ox)pSPGEATQSGAR_ DPAQPMS(0.999)PGEATQSGAR DPAQPMS(33.56)PGEAT(-33.56)QS(-36.65)GAR 7 2 898.36947 -0.19843 351410 2.9174 19890 0 0 331520 0 0 0 2151 1504 1290 1290 3054 3474 29138 18214 Mix4_TiO2_Reinj_1_5 6031 29138 18214 Mix4_TiO2_Reinj_1_5 6031 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.998988 29.944 0 0 0.998988 29.944 0.0816783 46.483 1 S KGVLGKSPLSALA NEK6;Proline-directed 0.05 0.0816783 46.483 _KGVLGKpSPLSALAR_ KGVLGKS(0.999)PLS(0.001)ALAR KGVLGKS(29.94)PLS(-29.94)ALAR 7 3 492.94811 -0.29143 127810 0 0 0 127810 0 0 0 2152 1504 1267 1267 3136;4272 3561;4862 29810 18560 Mix4_InSol_Tio2_Reinj_1 3015 29809 18559 Mix4_InSol_TiO2_1 3000 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.958262 13.6098 0.953155 13.085 0.000143563 94.249 0.958262 13.6098 0.0168504 61.192 1 S VNGAPGSPTEPAG CK2;ERK/MAPK;Proline-directed 0.0025 0.000143563 94.249 _KNQKPSQVNGAPGpSPTEPAGQK_ KNQKPSQVNGAPGS(0.958)PT(0.042)EPAGQK KNQKPS(-55.28)QVNGAPGS(13.61)PT(-13.61)EPAGQK 14 3 767.37254 -2.2767 586930 0 0 0 0 0 279180 307750 2153 1504 1308 1308 3724 4198 35132 21753 Mix4_TiO2_Reinj_1_5 6998 35132 21753 Mix4_TiO2_Reinj_1_5 6998 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.818455 6.54037 0 0 0.818455 6.54037 0.0155229 68.515 1 S LSLVIRSPSLLQS Proline-directed 0.05 0.0155229 68.515 _LSLVIRpSPSLLQSGAK_ LSLVIRS(0.818)PS(0.182)LLQSGAK LS(-62.14)LVIRS(6.54)PS(-6.54)LLQS(-48.74)GAK 7 3 583.66052 -0.58859 58515 0 0 0 58515 0 0 0 2154 1504 1241 1241 5544;5545 6318;6319 54243 33216 Mix4_InSol_TiO2_1 2910 54245 33218 Mix4_TiO2_Reinj_1_5 2694 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.835358 9.52989 0.0752953 -10.8338 0.00161498 86.268 0.438058 0 0.000761867 92.946 0.835358 9.52989 0.643693 28.865 0.0858946 -9.11845 0.938506 21.176 1 S PGAPTRSPSTPAK Proline-directed 0.05 0.000761867 92.946 _SPAPGAPTRpSPSTPAK_ S(0.006)PAPGAPT(0.093)RS(0.835)PS(0.053)T(0.013)PAK S(-21.28)PAPGAPT(-9.53)RS(9.53)PS(-11.99)T(-18.25)PAK 10 2 801.38779 0.15675 42508 0 0 0 0 0 42508 0 2155 1504 1243 1243 5544;5545 6318;6319 54244 33217 Mix4_TiO2_1_5 2176 54245 33218 Mix4_TiO2_Reinj_1_5 2694 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.912314 10.8338 0.912314 10.8338 0.00161498 86.268 0.0607497 -8.57987 0.000761867 92.946 0.0528265 -11.9902 0.643693 28.865 0.0996874 -8.47171 0.938506 21.176 1 S APTRSPSTPAKSP 14-3-3 binding;CAMK2;CK1 0.0001701 0.000761867 92.946 _SPAPGAPTRSPpSTPAK_ SPAPGAPT(0.012)RS(0.075)PS(0.912)TPAK S(-76.72)PAPGAPT(-18.69)RS(-10.83)PS(10.83)T(-41.48)PAK 12 2 801.38779 -0.4282 62165 62165 0 0 0 0 0 0 2156 1508 570 570 15 23 208 124 Mix4_TiO2_Reinj_1_5 3309 207 122 Mix4_TiO2_Reinj_1_3 3204 Q9BRK4 Q9BRK4 Q9BRK4 >sp|Q9BRK4|LZTS2_HUMAN Leucine zipper putative tumor suppressor 2 OS=Homo sapiens GN=LZTS2 PE=1 SV=2 1 28.6372 1 42.0737 0.0618624 42.074 0 0 1 28.6372 0.051461 45.518 1 10.9398 0.487633 13.478 0 0 1 S AAGVGGSLRAQVE 0.051461 45.518 _AAAGVGGpSLR_ AAAGVGGS(1)LR AAAGVGGS(28.64)LR 8 2 469.7264 0.036375 454530 53203 0 0 316780 0 84550 0 2157 1514 63 63 3897 4429 36933 22742 Mix4_TiO2_2_2 4241 36933 22742 Mix4_TiO2_2_2 4241 Q9BT25;Q9BT25-2 Q9BT25 Q9BT25 >sp|Q9BT25|HAUS8_HUMAN HAUS augmin-like complex subunit 8 OS=Homo sapiens GN=HAUS8 PE=1 SV=3;>sp|Q9BT25-2|HAUS8_HUMAN Isoform 2 of HAUS augmin-like complex subunit 8 OS=Homo sapiens GN=HAUS8 0.975549 19.0198 0.975549 19.0198 0.0817612 43.715 1 S QTRGKMSEGGRKS 0.0817612 43.715 _MpSEGGRKSSLLQK_ MS(0.976)EGGRKS(0.012)S(0.012)LLQK MS(19.02)EGGRKS(-19.02)S(-19.02)LLQK 2 2 750.86564 -1.5341 12191 0 12191 0 0 0 0 0 2158 1516 460 460 5737 6538 56393 34443 Mix4_InSol_Tio2_Reinj_1 4653 56394 34444 Mix4_TiO2_1_4 3798 Q9BTU6 Q9BTU6 Q9BTU6 >sp|Q9BTU6|P4K2A_HUMAN Phosphatidylinositol 4-kinase type 2-alpha OS=Homo sapiens GN=PI4K2A PE=1 SV=1 0.376995 0 0.277563 -2.04614 0.000115573 115.87 0.282317 -1.87896 0.000168129 114.06 0.351303 -0.507848 0.000290459 109.86 0.376995 0 0.00258238 89.578 1 S ARSHQRSSSESYT CK1;CK2;GSK3 0.081 0.000115573 115.87 _pSSSESYTQSFQSR_ S(0.377)S(0.377)S(0.246)ESYTQSFQSR S(0)S(0)S(-1.86)ES(-31.07)Y(-46.38)T(-56.74)QS(-87.43)FQS(-89.58)R 1 2 787.31195 -0.31307 0 0 0 0 0 0 0 0 2159 1516 461 461 5737 6538 56394 34444 Mix4_TiO2_1_4 3798 56394 34444 Mix4_TiO2_1_4 3798 Q9BTU6 Q9BTU6 Q9BTU6 >sp|Q9BTU6|P4K2A_HUMAN Phosphatidylinositol 4-kinase type 2-alpha OS=Homo sapiens GN=PI4K2A PE=1 SV=1 0.444606 2.04614 0.444606 2.04614 0.000115573 115.87 0.435145 1.87896 0.000168129 114.06 0.394882 0.507848 0.000290459 109.86 0.376995 0 0.00258238 89.578 1 S RSHQRSSSESYTQ PKA 0.042 0.000115573 115.87 _SpSSESYTQSFQSR_ S(0.278)S(0.445)S(0.278)ESYTQSFQSR S(-2.05)S(2.05)S(-2.05)ES(-32.22)Y(-59.94)T(-65.95)QS(-94.16)FQS(-110.97)R 2 2 787.31195 -0.3529 0 0 0 0 0 0 0 0 2160 1516 47 47 6320;6321 7222;7223;7224;7225 63342 38616 Mix4_TiO2_1_4 2514 63342 38616 Mix4_TiO2_1_4 2514 Q9BTU6 Q9BTU6 Q9BTU6 >sp|Q9BTU6|P4K2A_HUMAN Phosphatidylinositol 4-kinase type 2-alpha OS=Homo sapiens GN=PI4K2A PE=1 SV=1 0.999614 34.1467 0.999614 34.1467 2.19265E-06 108.34 0 0 0.842253 7.28 0.000282309 94.053 0.999935 41.8922 0.118366 50.144 0.706809 1.49449 1.85877 1.4945 1 S AAGSGPSPPGSPG CK1;GSK3;Proline-directed 0.05 2.19265E-06 108.34 _VAAAAGSGPpSPPGSPGHDR_ VAAAAGSGPS(1)PPGSPGHDR VAAAAGS(-58.96)GPS(34.15)PPGS(-34.15)PGHDR 10 2 884.39414 0.80531 459870 80522 0 0 379350 0 0 0 2161 1516 51 51 6320;6321 7222;7223;7224;7225 63333 38613 Mix4_TiO2_1_4 2559 63352 38624 Mix4_TiO2_Reinj_1_4 2857 Q9BTU6 Q9BTU6 Q9BTU6 >sp|Q9BTU6|P4K2A_HUMAN Phosphatidylinositol 4-kinase type 2-alpha OS=Homo sapiens GN=PI4K2A PE=1 SV=1 0.999999 62.7809 0.999999 62.7809 0.0102465 70.437 0 0 0.999999 60.7248 0.000209459 91.6 0.99999 49.932 0.118366 50.144 0.706809 1.49449 1.85877 1.4945 2 S GPSPPGSPGHDRE CK1;ERK/MAPK;Proline-directed 0.0025 0.000209459 91.6 _VAAAAGSGPpSPPGpSPGHDR_ VAAAAGSGPS(1)PPGS(1)PGHDR VAAAAGS(-50.1)GPS(50.1)PPGS(62.78)PGHDR 14 2 924.3773 0.21964 2493900 328830 0 0 1833000 0 279400 52726 2162 1517 105 105 6129 6996 60528 36591 Mix4_TiO2_Reinj_1_4 7545 60528 36591 Mix4_TiO2_Reinj_1_4 7545 Q9BTV7 Q9BTV7 Q9BTV7 >sp|Q9BTV7|CABL2_HUMAN CDK5 and ABL1 enzyme substrate 2 OS=Homo sapiens GN=CABLES2 PE=1 SV=3 0.497437 0 0 0 0.497437 0 0.000919314 79.243 1 S APQGLLSPTQVPT Proline-directed 0.05 0.000919314 79.243 _TPAPQGLLpSPTQVPTGLGLDGQR_ T(0.005)PAPQGLLS(0.497)PT(0.497)QVPTGLGLDGQR T(-19.87)PAPQGLLS(0)PT(0)QVPT(-52.14)GLGLDGQR 9 3 795.07209 0.19655 0 0 0 0 0 0 0 0 2163 1519 406 406 3119 3542;3543 29664 18465 Mix4_InSol_Tio2_Reinj_1 5169 29661 18462 Mix4_InSol_TiO2_1 5025 Q9BTX1;Q9BTX1-2;Q9BTX1-4 Q9BTX1 Q9BTX1 >sp|Q9BTX1|NDC1_HUMAN Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48 PE=1 SV=2;>sp|Q9BTX1-2|NDC1_HUMAN Isoform 2 of Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48;>sp|Q9BTX1-4|NDC1_HUMAN Isoform 4 of Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48 0.999929 41.8074 0.997537 26.0741 0.000183516 102.35 0 0 0.999456 32.64 1.41692E-07 136 0.999919 40.9125 1.14817E-08 138.13 0.999929 41.8074 0.000143565 105.81 1 S EPKKLNSPEETAF CK2;Proline-directed 0.05 1.14817E-08 138.13 _KLNpSPEETAFQTPK_ KLNS(1)PEETAFQTPK KLNS(41.81)PEET(-41.81)AFQT(-53.32)PK 4 2 835.39528 0.69862 1505400 233900 0 0 872570 0 201800 197140 2164 1519 474 474 3815 4311 36248 22393 Mix4_TiO2_Reinj_1_1 7043 36248 22393 Mix4_TiO2_Reinj_1_1 7043 Q9BTX1;Q9BTX1-2;Q9BTX1-4 Q9BTX1 Q9BTX1 >sp|Q9BTX1|NDC1_HUMAN Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48 PE=1 SV=2;>sp|Q9BTX1-2|NDC1_HUMAN Isoform 2 of Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48;>sp|Q9BTX1-4|NDC1_HUMAN Isoform 4 of Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48 0.999905 40.2303 0.788863 8.92338 1.52003 11.564 0.999905 40.2303 1.08692E-16 147.26 0 0 1 S CYGSPQSPQLIRR CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.08692E-16 147.26 _M(ox)AGIFDVNTCYGSPQpSPQLIR_ MAGIFDVNTCYGSPQS(1)PQLIR MAGIFDVNT(-73.45)CY(-80.08)GS(-40.23)PQS(40.23)PQLIR 16 2 1225.5476 0.19126 315550 42791 0 0 272760 0 0 0 2165 1521 35 35 3189 3619 30279 18840 Mix4_TiO2_Reinj_1_2 4317 30279 18840 Mix4_TiO2_Reinj_1_2 4317 Q9BU64;Q9BU64-2 Q9BU64 Q9BU64 >sp|Q9BU64|CENPO_HUMAN Centromere protein O OS=Homo sapiens GN=CENPO PE=1 SV=1;>sp|Q9BU64-2|CENPO_HUMAN Isoform 2 of Centromere protein O OS=Homo sapiens GN=CENPO 0.942674 12.1604 0 0 0 0 0.942674 12.1604 0.0734243 53.748 1 S SRSRKQSEELQSV CAMK2;CK1;PKA;PKA/AKT 0.001764 0.0734243 53.748 _KQpSEELQSVQAQEGALGTK_ KQS(0.943)EELQS(0.057)VQAQEGALGTK KQS(12.16)EELQS(-12.16)VQAQEGALGT(-53.75)K 3 3 704.33872 -0.31322 32088 0 0 0 32088 0 0 0 2166 1523 192 192 680 781 6518 3889 Mix4_TiO2_Reinj_2_1 2239 6518 3889 Mix4_TiO2_Reinj_2_1 2239 Q9BUH6 Q9BUH6 Q9BUH6 >sp|Q9BUH6|CI142_HUMAN Uncharacterized protein C9orf142 OS=Homo sapiens GN=C9orf142 PE=1 SV=2 1 84.5907 0.999998 58.0506 0.0294695 58.883 0.999999 61.3274 0.0166245 67.01 0.999998 57.5301 0.0166245 67.01 1 84.5907 0.00243331 85.464 0.988757 19.4419 0.564783 19.442 0 0 1 S INPGFKSKKPAGG 0.00243331 85.464 _CPGESLINPGFKpSK_ CPGESLINPGFKS(1)K CPGES(-84.59)LINPGFKS(84.59)K 13 2 807.3733 0.31537 5970900 1101100 3099400 0 1651700 100320 18401 0 2167 1523 152 152 3217 3649 30503 18957 Mix4_TiO2_Reinj_1_6 5789 30503 18957 Mix4_TiO2_Reinj_1_6 5789 Q9BUH6 Q9BUH6 Q9BUH6 >sp|Q9BUH6|CI142_HUMAN Uncharacterized protein C9orf142 OS=Homo sapiens GN=C9orf142 PE=1 SV=2 1 53.0329 1 53.0329 0.0792431 53.033 1 S AVSPRKSPRPAGP CDK1;CK1;PKA;Proline-directed 0.0057 0.0792431 53.033 _KpSPRPAGPQLFLPDPDPQR_ KS(1)PRPAGPQLFLPDPDPQR KS(53.03)PRPAGPQLFLPDPDPQR 2 3 732.70356 0.30677 22653 0 0 0 22653 0 0 0 2168 1523 148 148 3281 3716 30990 19216 Mix4_TiO2_1_6 2449 30990 19216 Mix4_TiO2_1_6 2449 Q9BUH6 Q9BUH6 Q9BUH6 >sp|Q9BUH6|CI142_HUMAN Uncharacterized protein C9orf142 OS=Homo sapiens GN=C9orf142 PE=1 SV=2 1 63.4182 1 63.4182 0.00606573 81.147 0 0 0.999765 36.2796 0.0553196 49.441 1 S AEETAVSPRKSPR CDK1;CDK2;GSK3;Proline-directed 0.0057 0.00606573 81.147 _LAAAEETAVpSPR_ LAAAEETAVS(1)PR LAAAEET(-63.42)AVS(63.42)PR 10 2 647.80557 0.49198 68287 16907 0 0 51379 0 0 0 2169 1524 716 716 406;407 464;465 3884 2319 Mix4_InSol_TiO2_1 5461 3865 2312 Mix4_TiO2_Reinj_1_5 4826 Q9BUJ2;Q9BUJ2-2;Q9BUJ2-4;Q9BUJ2-3;Q9BUJ2-5 Q9BUJ2 Q9BUJ2 >sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2;>sp|Q9BUJ2-2|HNRL1_HUMAN Isoform Isoform b of Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1;>sp|Q9B 0.419745 0 0.351461 0.349708 4.68498E-19 139.13 0 0 0.333333 0 6.30364E-20 154.34 0 0 0.419745 0 0.0721543 77.164 0.32755 0 0.082727 76.776 1 S QPPPPPSYSPARN 6.30364E-20 154.34 _APQQQPPPQQPPPPQPPPQQPPPPPpSYSPARNPPGASTYNK_ APQQQPPPQQPPPPQPPPQQPPPPPS(0.42)Y(0.42)S(0.102)PARNPPGAS(0.011)T(0.011)Y(0.036)NK APQQQPPPQQPPPPQPPPQQPPPPPS(0)Y(0)S(-6.14)PARNPPGAS(-15.81)T(-15.81)Y(-10.61)NK 26 4 1110.2906 -0.2266 0 0 0 0 0 0 0 0 2170 1524 718 718 406;407 464;465 3858 2294 Mix4_TiO2_1_5 4565 3865 2312 Mix4_TiO2_Reinj_1_5 4826 Q9BUJ2;Q9BUJ2-2;Q9BUJ2-4;Q9BUJ2-3;Q9BUJ2-5 Q9BUJ2 Q9BUJ2 >sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2;>sp|Q9BUJ2-2|HNRL1_HUMAN Isoform Isoform b of Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1;>sp|Q9B 0.959651 14.6425 0.959651 14.6425 4.68498E-19 139.13 0 0 0.513669 3.24782 6.30364E-20 154.34 0 0 0.333333 0 0.0721543 77.164 0.32755 0 0.082727 76.776 1 S PPPPSYSPARNPP CDK1;CDK2;Proline-directed 0.0057 6.30364E-20 154.34 _APQQQPPPQQPPPPQPPPQQPPPPPSYpSPAR_ APQQQPPPQQPPPPQPPPQQPPPPPS(0.007)Y(0.033)S(0.96)PAR APQQQPPPQQPPPPQPPPQQPPPPPS(-21.13)Y(-14.64)S(14.64)PAR 28 3 1136.889 -0.49711 8775700 567350 0 0 8208400 0 0 0 2171 1524 194 194 2421;4886;5575 2744;5557;6352 46931 28726 Mix4_TiO2_Reinj_1_5 8380 46931 28726 Mix4_TiO2_Reinj_1_5 8380 Q9BUJ2;Q9BUJ2-2;Q9BUJ2-4;Q9BUJ2-3 Q9BUJ2 Q9BUJ2 >sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2;>sp|Q9BUJ2-2|HNRL1_HUMAN Isoform Isoform b of Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1;>sp|Q9B 1 79.8145 1 86.7867 3.55681E-19 144.62 0.999992 50.8912 1.31552E-07 101.37 1 79.8145 2.45352E-37 190.34 0.997599 26.2434 0.0422248 67.872 0.999476 36.3383 0.933471 44.618 0.962691 18.123 1.59114 29.685 1 S EDRRGRSPQPPAE CAMK2;Proline-directed 0.042 2.45352E-37 190.34 _RGRpSPQPPAEEDEDDFDDTLVAIDTYNCDLHFK_ RGRS(1)PQPPAEEDEDDFDDTLVAIDTYNCDLHFK RGRS(79.81)PQPPAEEDEDDFDDT(-79.81)LVAIDT(-153.81)Y(-162.02)NCDLHFK 4 4 987.17819 -0.25808 75578000 1350.6 7043100 161000 0 67832000 66867 192730 282130 2172 1524 512 512 4393 4997 41772 25716 Mix4_TiO2_1_3 5296 41772 25716 Mix4_TiO2_1_3 5296 Q9BUJ2;Q9BUJ2-2;Q9BUJ2-4;Q9BUJ2-3 Q9BUJ2 Q9BUJ2 >sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2;>sp|Q9BUJ2-2|HNRL1_HUMAN Isoform Isoform b of Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1;>sp|Q9B 1 67.8009 1 67.8009 6.69335E-07 119.15 0 0 0 0 0 0 1 S QTNVYGSAQRRKM 6.69335E-07 119.15 _NYILDQTNVYGpSAQR_ NYILDQTNVYGS(1)AQR NY(-119.15)ILDQT(-94.41)NVY(-67.8)GS(67.8)AQR 12 2 911.412 0.32177 114730 0.98732 114730 0 0 0 0 0 0 2173 1525 201 201 4024 4583 38033 23350 Mix4_TiO2_Reinj_1_6 7137 38033 23350 Mix4_TiO2_Reinj_1_6 7137 Q9BUN8 Q9BUN8 Q9BUN8 >sp|Q9BUN8|DERL1_HUMAN Derlin-1 OS=Homo sapiens GN=DERL1 PE=1 SV=1 0.756192 4.9163 0 0 0.756192 4.9163 0.00882967 65.299 1 S GGRNFLSTPQFLY 14-3-3 binding 0.0001533 0.00882967 65.299 _NFLpSTPQFLYR_ NFLS(0.756)T(0.244)PQFLYR NFLS(4.92)T(-4.92)PQFLY(-44.54)R 4 2 733.34741 0.35487 15535 0.30778 0 0 0 15535 0 0 0 2174 1527 197 197 2091 2368 19150 11643 Mix4_TiO2_Reinj_1_2 2246 19150 11643 Mix4_TiO2_Reinj_1_2 2246 Q9BVG4 Q9BVG4 Q9BVG4 >sp|Q9BVG4|CX026_HUMAN UPF0368 protein Cxorf26 OS=Homo sapiens GN=CXorf26 PE=1 SV=1 1 53.1422 1 53.1422 0.0732844 53.142 1 S GEKGADSGEEKEE CK2 0.117 0.0732844 53.142 _GADpSGEEKEEGINREDK_ GADS(1)GEEKEEGINREDK GADS(53.14)GEEKEEGINREDK 4 3 648.27238 -0.018733 64665 0 0 0 64665 0 0 0 2175 1528 16 16 723;4826 828;5479 46093 28175 Mix4_TiO2_Reinj_1_5 2872 6962 4126 Mix4_InSol_TiO2_1 3296 Q9BVG9 Q9BVG9 Q9BVG9 >sp|Q9BVG9|PTSS2_HUMAN Phosphatidylserine synthase 2 OS=Homo sapiens GN=PTDSS2 PE=1 SV=1 1 13.3274 1 38.1203 0.000489497 96.121 1 40.5118 0.142929 40.512 1 13.3274 6.63664E-05 104.54 1 21.2226 4.21985E-05 109.53 1 11.813 0.00215179 84.851 1 S GGPRPESPVPAGR CAMK2;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 4.21985E-05 109.53 _RDAGGPRPEpSPVPAGR_ RDAGGPRPES(1)PVPAGR RDAGGPRPES(13.33)PVPAGR 10 3 566.94057 0.24584 10412000 1337300 60337 0 6192200 0 1587100 1235500 2176 1530 350 350 199;200 230;232 2094 1383 Mix4_TiO2_1_3 2407 2096 1390 Mix4_TiO2_Reinj_1_3 3035 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.999962 44.2456 0.999962 44.2456 0.000562418 109.84 0 0 0.999932 41.735 0.000107577 121.36 0 0 0 0 1 S KAEVYGSENESER CK2;GSK3 0.081 0.000107577 121.36 _AEVYGpSENESER_ AEVYGS(1)ENESER AEVY(-61.73)GS(44.25)ENES(-44.25)ER 6 2 725.28012 -0.15912 12923000 255.22 2820200 0 0 10103000 0 0 0 2177 1530 332 332 1559 1751;1752 14277 8698 Mix4_TiO2_Reinj_1_3 6359 14277 8698 Mix4_TiO2_Reinj_1_3 6359 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.999946 42.6762 0.996701 24.769 1.83194E-06 117.85 0 0 0.999946 42.6762 1.17891E-07 134.26 0 0 2.23375E-10 -96.5097 3.09395E-10 155.38 1.86902E-06 -57.2735 5.05649E-07 123.62 2 S IETKEGSEFSFSD CK1 0.143 1.17891E-07 134.26 _EGpSEFSFpSDGEVAEK_ EGS(1)EFSFS(1)DGEVAEK EGS(42.68)EFS(-42.68)FS(42.68)DGEVAEK 3 2 889.31571 0.73117 2863600 72575 0 0 2791000 0 0 0 2178 1530 335 335 1559 1751;1752 14275 8693 Mix4_TiO2_1_3 5726 14277 8698 Mix4_TiO2_Reinj_1_3 6359 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.689644 3.46581 0.689644 3.46581 1.83194E-06 117.85 0 0 0.000331316 -34.7961 8.26244E-10 153.16 0 0 2.55772E-07 -65.9215 3.09395E-10 155.38 0.00237069 -26.2409 5.05649E-07 123.62 2 S KEGSEFSFSDGEV CK1;CK2;PLK1 0.033462 1.17891E-07 134.26 _EGSEFpSFpSDGEVAEK_ EGS(0.311)EFS(0.69)FS(1)DGEVAEK EGS(-3.47)EFS(3.47)FS(33.75)DGEVAEK 6 2 889.31571 0.11941 1295300 1295300 0 0 0 0 0 0 2179 1530 337 337 1559 1751;1752 14253 8670 Mix4_InSol_TiO2_1 6562 14258 8680 Mix4_TiO2_1_4 5412 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 1 65.9215 0.999996 53.8309 1.88904E-16 189.17 0 0 0.999997 55.7905 8.26244E-10 153.16 0 0 1 65.9215 3.09395E-10 155.38 0.997627 26.2409 5.05649E-07 123.62 1 S GSEFSFSDGEVAE CK2 0.117 1.88904E-16 189.17 _EGSEFSFpSDGEVAEK_ EGSEFSFS(1)DGEVAEK EGS(-96.51)EFS(-65.92)FS(65.92)DGEVAEK 8 2 849.33255 0.0096385 20858000 5063500 0 0 15424000 0 181150 189470 2180 1530 412 412 2400 2719 22394 13962 Mix4_TiO2_1_3 4204 22394 13962 Mix4_TiO2_1_3 4204 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.996803 24.9384 0.996803 24.9384 1.27502E-25 196.49 0.619394 2.11491 6.59902E-21 193.85 1 S QVVENNSVTEFSE CK2 0.117 1.27502E-25 196.49 _GQVVENNpSVTEFSEEK_ GQVVENNS(0.997)VT(0.003)EFSEEK GQVVENNS(24.94)VT(-24.94)EFS(-94.61)EEK 8 2 938.40404 1.204 538550 0.35204 141790 0 0 396760 0 0 0 2181 1530 390 390 5261 5989 51079 31277 Mix4_TiO2_1_3 7357 51079 31277 Mix4_TiO2_1_3 7357 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 1 84.506 1 84.506 4.96838E-16 179.33 0 0 1 S ESADARSFEMTEF 4.96838E-16 179.33 _pSFEM(ox)TEFNQALEEIK_ S(1)FEMTEFNQALEEIK S(84.51)FEMT(-84.51)EFNQALEEIK 1 2 956.40773 0.12876 57441 57441 0 0 0 0 0 0 2182 1530 370 370 5706 6501;6503 55987 34274 Mix4_TiO2_Reinj_1_3 4685 55974 34257 Mix4_InSol_Tio2_Reinj_1 4614 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.577878 1.36398 0.571836 1.25662 1.04294E-16 147.64 0 0 0.577878 1.36398 2.43256E-11 131.43 9.81353E-05 -40.0343 9.54496E-12 135.05 0.191432 -0.877013 7.65882E-17 150.04 1 S GCYCRSSGDPEQI PKA 0.042 7.65882E-17 150.04 _SpSGDPEQIKEDSLSEESADAR_ S(0.422)S(0.578)GDPEQIKEDSLSEESADAR S(-1.36)S(1.36)GDPEQIKEDS(-63.45)LS(-116.08)EES(-122.88)ADAR 2 3 777.3271 0.074429 2666900 0.4428 616690 0 0 2050200 0 0 0 2183 1530 380 380 5706 6501;6503 55978 34261 Mix4_TiO2_1_3 3546 55974 34257 Mix4_InSol_Tio2_Reinj_1 4614 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.992982 21.5342 0.992982 21.5342 1.04294E-16 147.64 0 0 0.991381 20.6118 2.43256E-11 131.43 0.992731 21.3539 9.54496E-12 135.05 0.969272 15.0278 7.65882E-17 150.04 1 S EQIKEDSLSEESA CK2;PLK;PLK1 0.0027378 7.65882E-17 150.04 _SSGDPEQIKEDpSLSEESADAR_ SSGDPEQIKEDS(0.993)LS(0.007)EESADAR S(-52.05)S(-51.55)GDPEQIKEDS(21.53)LS(-21.53)EES(-45.11)ADAR 12 2 1165.487 0.82974 10312000 1.7122 143390 0 0 7714800 0 1649600 804410 2184 1530 382 382 5706 6501;6503 55976 34259 Mix4_InSol_Tio2_Reinj_1 4742 55974 34257 Mix4_InSol_Tio2_Reinj_1 4614 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.985056 18.2678 0.936053 11.6548 1.04294E-16 147.64 0 0 0.999826 37.5917 0.000124389 94.548 0.137873 -7.95989 9.54496E-12 135.05 0.985056 18.2678 7.65882E-17 150.04 1 S IKEDSLSEESADA 7.65882E-17 150.04 _SSGDPEQIKEDSLpSEESADAR_ SSGDPEQIKEDSLS(0.985)EES(0.015)ADAR S(-70.42)S(-70.42)GDPEQIKEDS(-35.7)LS(18.27)EES(-18.27)ADAR 14 2 1165.487 0.16417 3552900 0.58991 3280100 0 0 0 0 0 272800 2185 1530 385 385 5706 6501;6503 56056 34292 Mix4_TiO2_1_3 3674 56057 34293 Mix4_TiO2_Reinj_1_3 4275 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.749173 4.33834 0.749173 4.33834 0.000745888 79.32 0 0 0.00419992 -21.5475 2.43256E-11 131.43 0.0565139 -12.0475 9.54496E-12 135.05 0.191432 -0.877013 7.65882E-17 150.04 2 S DSLSEESADARSF CK1 0.081 0.000124389 94.548 _SSGDPEQIKEDSLpSEEpSADAR_ SSGDPEQIKEDS(0.319)LS(0.932)EES(0.749)ADAR S(-70.25)S(-69.7)GDPEQIKEDS(-4.34)LS(10)EES(4.34)ADAR 17 3 803.98254 -0.13323 365960 0.060761 365960 0 0 0 0 0 0 2186 1530 483 483 6087 6942;6943 60146 36435 Mix4_TiO2_Reinj_1_3 7062 60147 36438 Mix4_TiO2_Reinj_1_3 7067 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.75953 7.69074 0.183331 -6.50814 0.00549498 74.017 0.75953 7.69074 0.000203383 92.329 0.452875 0.566389 0.026846 59.447 0.405749 0.487629 0.51042 36.01 1 S YRTRTLSITSSGS CAMK2;CK1;GSK3;PKA/AKT 0.00111111 0.000203383 92.329 _TLpSITSSGSAVSCSTIPPELVK_ T(0.084)LS(0.76)IT(0.129)S(0.023)S(0.004)GSAVSCSTIPPELVK T(-9.55)LS(7.69)IT(-7.69)S(-15.25)S(-22.66)GS(-38.57)AVS(-78.34)CS(-90.34)T(-90.34)IPPELVK 3 2 1157.566 0.9632 1020400 0 0 0 1020400 0 0 0 2187 1530 486 486 6087 6942;6943 60143 36430 Mix4_InSol_Tio2_Reinj_1 7473 60147 36438 Mix4_TiO2_Reinj_1_3 7067 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.222246 0 0.11752 -6.50814 0.00549498 74.017 0.205059 -6.69219 8.10349E-07 102.14 0.0289804 -14.2413 0.026846 59.447 0.222246 0 0.51042 36.01 1 S RTLSITSSGSAVS CK1 0.081 0.000203383 92.329 _TLpSITSSGSAVSCSTIPPELVK_ T(0.2)LS(0.222)IT(0.222)S(0.222)S(0.038)GS(0.038)AVS(0.045)CS(0.01)T(0.002)IPPELVK T(-0.45)LS(0)IT(0)S(0)S(-7.71)GS(-7.71)AVS(-6.89)CS(-13.57)T(-19.56)IPPELVK 6 3 772.04644 -0.28267 0 0 0 0 0 0 0 0 2188 1530 487 487 6087 6942;6943 60154 36440 Mix4_TiO2_Reinj_1_3 7149 60154 36440 Mix4_TiO2_Reinj_1_3 7149 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.791847 7.76361 0.515254 1.74634 0.00549498 74.017 0.791847 7.76361 8.10349E-07 102.14 0.0191224 -13.7444 0.026846 59.447 0.0376293 -7.71308 0.51042 36.01 2 S TLSITSSGSAVSC CK1 0.143 8.10349E-07 102.14 _TLpSITSpSGSAVSCSTIPPELVK_ T(0.328)LS(0.492)IT(0.119)S(0.205)S(0.792)GS(0.063)AVSCSTIPPELVK T(-1.87)LS(1.87)IT(-6.69)S(-6.69)S(7.76)GS(-11.36)AVS(-36.31)CS(-48.92)T(-48.92)IPPELVK 7 3 798.70188 0.021984 432990 65591 0 0 367400 0 0 0 2189 1530 442 442 6561 7505 66397 40760 Mix4_TiO2_1_3 6623 66397 40760 Mix4_TiO2_1_3 6623 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.999898 39.9237 0.999898 39.9237 1.30285E-18 152.95 0.993141 21.6073 1.76405E-07 104.62 0.772299 5.30422 0.000165488 87.335 0.995202 23.1708 0.035651 60 1 S GGVPAGSDEYEDE 1.30285E-18 152.95 _VQGGVPAGpSDEYEDECPHLIALSSLNR_ VQGGVPAGS(1)DEYEDECPHLIALSSLNR VQGGVPAGS(39.92)DEY(-39.92)EDECPHLIALS(-128.33)S(-133.25)LNR 9 3 998.44974 -0.81839 11903000 2.6188 2186300 0 0 8094700 0 756610 865730 2190 1533 95 95 5945 6778 58567 35513 Mix4_InSol_Tio2_Reinj_1 2934 58567 35513 Mix4_InSol_Tio2_Reinj_1 2934 Q9BW61 Q9BW61 Q9BW61 >sp|Q9BW61|DDA1_HUMAN DET1- and DDB1-associated protein 1 OS=Homo sapiens GN=DDA1 PE=1 SV=1 0.999894 39.7501 0.911405 13.1333 0.495606 13.133 0.999894 39.7501 0.00264818 73.689 1 S KVARTDSPDMHED CAMK2;CHK1;PKD;Proline-directed 0.020748 0.00264818 73.689 _TDpSPDMHEDT_ TDS(1)PDMHEDT T(-39.75)DS(39.75)PDMHEDT(-73.69) 3 2 614.19721 -0.80956 65146 0 0 0 0 0 33250 31897 2191 1534 72 72 1334 1503 12458 7601 Mix4_TiO2_Reinj_1_5 8557 12457 7600 Mix4_TiO2_1_5 7825 Q9BWH6;Q9BWH6-2 Q9BWH6 Q9BWH6 >sp|Q9BWH6|RPAP1_HUMAN RNA polymerase II-associated protein 1 OS=Homo sapiens GN=RPAP1 PE=1 SV=3;>sp|Q9BWH6-2|RPAP1_HUMAN Isoform 2 of RNA polymerase II-associated protein 1 OS=Homo sapiens GN=RPAP1 1 87.0545 1 112.603 2.79492E-07 112.6 1 87.0545 0.000367752 87.054 1 S PPALVPSPPKRAR CDK1;CDK2;ERK/MAPK;NEK6;Proline-directed 0.0034 2.79492E-07 112.6 _DVVMLDNLPDLPPALVPpSPPKR_ DVVMLDNLPDLPPALVPS(1)PPKR DVVMLDNLPDLPPALVPS(87.05)PPKR 18 3 821.76209 0.021068 240730 56196 0 0 184530 0 0 0 2192 1536 239 239 3411 3853 32068 19819 Mix4_TiO2_2_4 5849 32068 19819 Mix4_TiO2_2_4 5849 Q9BX70 Q9BX70 Q9BX70 >sp|Q9BX70|BTBD2_HUMAN BTB/POZ domain-containing protein 2 OS=Homo sapiens GN=BTBD2 PE=1 SV=1 1 49.1077 1 49.1077 0.111561 49.108 1 S DEPQLASLCLENI 0.111561 49.108 _LFDEPQLApSLCLENIDK_ LFDEPQLAS(1)LCLENIDK LFDEPQLAS(49.11)LCLENIDK 9 2 1042.9841 -3.9522 0 0 0 0 0 0 0 0 2193 1537 112 112 4311;4968 4904;5649 40940 25191 Mix4_TiO2_Reinj_1_6 3921 47931 29307 Mix4_TiO2_1_4 3639 Q9BX95 Q9BX95 Q9BX95 >sp|Q9BX95|SGPP1_HUMAN Sphingosine-1-phosphate phosphatase 1 OS=Homo sapiens GN=SGPP1 PE=1 SV=2 0.999994 52.2042 0.999989 49.5194 2.0251E-06 149.63 0.747672 4.71746 0.0592799 49.823 0.999994 52.2042 0.00012709 115.47 0.105156 -9.29913 0.00430268 81.524 0.0991685 -9.5827 0.0015514 94.405 1 S GALRRNSLTGEEG AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.00111111 2.0251E-06 149.63 _NpSLTGEEGQLAR_ NS(1)LTGEEGQLAR NS(52.2)LT(-52.2)GEEGQLAR 2 2 677.80356 0.55833 14385000 2660500 25731 0 11698000 0 0 0 2194 1538 189 189 5002 5688 48275 29487 Mix4_TiO2_Reinj_1_3 6715 48275 29487 Mix4_TiO2_Reinj_1_3 6715 Q9BXB4 Q9BXB4 Q9BXB4 >sp|Q9BXB4|OSB11_HUMAN Oxysterol-binding protein-related protein 11 OS=Homo sapiens GN=OSBPL11 PE=1 SV=2 1 70.8007 0 0 1 70.8007 9.08124E-06 105.41 1 S ISQRRPSQNAISF CAMK2;PKA 0.004788 9.08124E-06 105.41 _RPpSQNAISFFNVGHSK_ RPS(1)QNAISFFNVGHSK RPS(70.8)QNAIS(-70.8)FFNVGHS(-105.41)K 3 3 623.63163 -0.43241 264220 0 0 0 264220 0 0 0 2195 1539 29 29 579 663 5475 3267 Mix4_InSol_Tio2_Reinj_1 3436 5475 3267 Mix4_InSol_Tio2_Reinj_1 3436 Q9BXB5 Q9BXB5 Q9BXB5 >sp|Q9BXB5|OSB10_HUMAN Oxysterol-binding protein-related protein 10 OS=Homo sapiens GN=OSBPL10 PE=1 SV=2 0.738651 8.42901 0 0 0 0 0.209414 -5.13373 0.365318 31.505 0.738651 8.42901 0.0834615 49.7 1 S RATSAGSSPSCSL CK1 0.081 0.0834615 49.7 _ATSAGpSSPSCSLAGR_ AT(0.037)S(0.037)AGS(0.739)S(0.08)PS(0.106)CS(0.001)LAGR AT(-12.95)S(-12.95)AGS(8.43)S(-9.67)PS(-8.43)CS(-29.93)LAGR 6 2 744.81106 0.99412 26046 0 0 0 0 0 0 26046 2196 1539 30 30 579 663 5474 3266 Mix4_InSol_TiO2_1 3446 5475 3267 Mix4_InSol_Tio2_Reinj_1 3436 Q9BXB5 Q9BXB5 Q9BXB5 >sp|Q9BXB5|OSB10_HUMAN Oxysterol-binding protein-related protein 10 OS=Homo sapiens GN=OSBPL10 PE=1 SV=2 0.682933 5.13373 0 0 0 0 0.682933 5.13373 0.365318 31.505 0.0796529 -9.67237 0.0834615 49.7 1 S ATSAGSSPSCSLA CK1;GSK3;Polo box;Proline-directed 0.00405 0.0834615 49.7 _ATSAGSpSPSCSLAGR_ ATS(0.006)AGS(0.209)S(0.683)PS(0.1)CS(0.001)LAGR AT(-31.5)S(-20.56)AGS(-5.13)S(5.13)PS(-8.33)CS(-29.68)LAGR 7 2 744.81106 0.049533 34972 0 0 0 0 0 34972 0 2197 1540 5 5 3837 4337 36375 22456 Mix4_TiO2_1_4 4223 36375 22456 Mix4_TiO2_1_4 4223 Q9BXM0;Q9BXM0-3;Q9BXM0-2 Q9BXM0 Q9BXM0 >sp|Q9BXM0|PRAX_HUMAN Periaxin OS=Homo sapiens GN=PRX PE=1 SV=1;>sp|Q9BXM0-3|PRAX_HUMAN Isoform 3 of Periaxin OS=Homo sapiens GN=PRX;>sp|Q9BXM0-2|PRAX_HUMAN Isoform S-periaxin of Periaxin OS=Homo sapiens GN=PRX 0.739125 4.52285 0.739125 4.52285 0.101327 32.504 1 S __MEARSRSAEEL 0.101327 32.504 _(ac)MEARpSRSAEELR_ MEARS(0.739)RS(0.261)AEELR MEARS(4.52)RS(-4.52)AEELR 5 2 778.84798 -5.0129 0 0 0 0 0 0 0 0 2198 1542 752 752 4456 5067 42324 26042 Mix4_TiO2_Reinj_1_1 3756 42324 26042 Mix4_TiO2_Reinj_1_1 3756 Q9BXS9;Q9BXS9-2 Q9BXS9 Q9BXS9 >sp|Q9BXS9|S26A6_HUMAN Solute carrier family 26 member 6 OS=Homo sapiens GN=SLC26A6 PE=1 SV=1;>sp|Q9BXS9-2|S26A6_HUMAN Isoform 2 of Solute carrier family 26 member 6 OS=Homo sapiens GN=SLC26A6 0.998421 29.9545 0.988183 19.6631 0.0446969 50.208 0.0645773 -11.217 0.425362 15.834 0.998421 29.9545 0.0275029 55.307 0 0 0 0 0 0 1 S PRPVPDSPVSVTR ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0275029 55.307 _PVPDpSPVSVTR_ PVPDS(0.998)PVS(0.001)VT(0.001)R PVPDS(29.95)PVS(-29.95)VT(-32.43)R 5 2 617.29739 0.25172 83246 30099 0 0 53147 0 0 0 2199 1543 216 216 3312 3748 31256 19354 Mix4_TiO2_Reinj_2_1 2068 31253 19349 Mix4_TiO2_2_1 1567 Q9BXU1;Q9BXU1-2 Q9BXU1 Q9BXU1 >sp|Q9BXU1|STK31_HUMAN Serine/threonine-protein kinase 31 OS=Homo sapiens GN=STK31 PE=2 SV=2;>sp|Q9BXU1-2|STK31_HUMAN Isoform 2 of Serine/threonine-protein kinase 31 OS=Homo sapiens GN=STK31 0.897293 9.41332 0.5 0 0.273552 25.704 0.5 0 0.0775242 43.155 0.5 0 0.145189 36.101 0.897293 9.41332 0.179359 33.334 1 S EKCRLASRTDICE CAMK2;CK2 0.042 0.0775242 43.155 _LApSRTDICEEKK_ LAS(0.897)RT(0.103)DICEEKK LAS(9.41)RT(-9.41)DICEEKK 3 2 765.35511 -1.128 2295900 71133 496840 0 1273700 454240 0 0 2200 1544 1435 1435 559 639 5302 3203 Mix4_TiO2_Reinj_1_5 2889 5302 3203 Mix4_TiO2_Reinj_1_5 2889 Q9BXW9-2 Q9BXW9-2 Q9BXW9-2 >sp|Q9BXW9-2|FACD2_HUMAN Isoform 2 of Fanconi anemia group D2 protein OS=Homo sapiens GN=FANCD2 1 116.77 0 0 1 116.77 3.19424E-07 128.73 1 S GEEDEVSAGEKEQ CK2 0.117 3.19424E-07 128.73 _ATEDGEEDEVpSAGEK_ ATEDGEEDEVS(1)AGEK AT(-116.77)EDGEEDEVS(116.77)AGEK 11 2 823.30927 0.16209 121280 0 0 0 121280 0 0 0 2201 1544 592 592 5248 5974 50965 31242 Mix4_TiO2_Reinj_1_5 3311 50965 31242 Mix4_TiO2_Reinj_1_5 3311 Q9BXW9-2;Q9BXW9;Q9BXW9-3 Q9BXW9-2 Q9BXW9-2 >sp|Q9BXW9-2|FACD2_HUMAN Isoform 2 of Fanconi anemia group D2 protein OS=Homo sapiens GN=FANCD2;>sp|Q9BXW9|FACD2_HUMAN Fanconi anemia group D2 protein OS=Homo sapiens GN=FANCD2 PE=1 SV=1;>sp|Q9BXW9-3|FACD2_HUMAN Isoform 3 of Fanconi anemia group D2 protein 0.975666 16.0631 0.930096 11.7212 0.00133473 90.444 0.975666 16.0631 0.00158788 95.239 0 0 0 0 1 S AADRSESPSLTQE CAMK2;PKA/AKT;Proline-directed 0.00111111 0.00158788 95.239 _SEpSPSLTQER_ SES(0.976)PS(0.024)LTQER S(-37.36)ES(16.06)PS(-16.06)LT(-59.28)QER 3 2 607.25846 0.55885 223950 40547 0 0 183400 0 0 0 2202 1547 503 503 5171 5887 50105 30621 Mix4_InSol_TiO2_1 4320 50107 30623 Mix4_TiO2_1_3 3340 Q9BY44;Q9BY44-2 Q9BY44 Q9BY44 >sp|Q9BY44|EIF2A_HUMAN Eukaryotic translation initiation factor 2A OS=Homo sapiens GN=EIF2A PE=1 SV=3;>sp|Q9BY44-2|EIF2A_HUMAN Isoform 2 of Eukaryotic translation initiation factor 2A OS=Homo sapiens GN=EIF2A 0.928479 11.1334 0.203115 -5.93636 4.78059E-05 98.326 0.49978 0 0.00128179 83.279 0.928479 11.1334 0.00158429 79.567 0 0 1 S AKQEARSDKSPDL 4.78059E-05 98.326 _pSDKSPDLAPTPAPQSTPR_ S(0.928)DKS(0.072)PDLAPTPAPQSTPR S(11.13)DKS(-11.13)PDLAPT(-79.57)PAPQS(-79.57)T(-79.57)PR 1 2 972.95677 0.013978 60032 0 0 0 0 0 60032 0 2203 1547 506 506 5171 5887 50107 30623 Mix4_TiO2_1_3 3340 50107 30623 Mix4_TiO2_1_3 3340 Q9BY44;Q9BY44-2 Q9BY44 Q9BY44 >sp|Q9BY44|EIF2A_HUMAN Eukaryotic translation initiation factor 2A OS=Homo sapiens GN=EIF2A PE=1 SV=3;>sp|Q9BY44-2|EIF2A_HUMAN Isoform 2 of Eukaryotic translation initiation factor 2A OS=Homo sapiens GN=EIF2A 0.966727 14.6322 0.966727 14.6322 4.78059E-05 98.326 0.830165 6.91177 0.00128179 83.279 0.14699 -7.48478 0.00158429 79.567 0 0 1 S EARSDKSPDLAPT CK1;Proline-directed 0.05 4.78059E-05 98.326 _SDKpSPDLAPTPAPQSTPR_ S(0.033)DKS(0.967)PDLAPTPAPQSTPR S(-14.63)DKS(14.63)PDLAPT(-64.13)PAPQS(-98.33)T(-98.33)PR 4 3 648.97361 0.37819 721550 154280 0 0 567270 0 0 0 2204 1550 338 338 5766 6571 56771 34632 Mix4_TiO2_1_1 3727 56771 34632 Mix4_TiO2_1_1 3727 Q9BYK8 Q9BYK8 Q9BYK8 >sp|Q9BYK8|PR285_HUMAN Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein OS=Homo sapiens GN=PRIC285 PE=1 SV=5 0.987304 18.9083 0.987304 18.9083 1.17759E-06 125.1 0.872284 8.34439 1.64937E-05 116.82 1 S VASGPISPTNYRQ CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.17759E-06 125.1 _SSVASGPIpSPTNYR_ SSVASGPIS(0.987)PT(0.013)NYR S(-109.93)S(-108.94)VAS(-71.32)GPIS(18.91)PT(-18.91)NY(-60.43)R 9 2 758.3456 0.73625 313530 45619 0 0 267910 0 0 0 2205 1551 470 470 1057 1188;1189 9958 6075 Mix4_InSol_TiO2_1 5925 9958 6075 Mix4_InSol_TiO2_1 5925 Q9BYT3;Q9BYT3-2 Q9BYT3 Q9BYT3 >sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo sapiens GN=STK33 PE=1 SV=1;>sp|Q9BYT3-2|STK33_HUMAN Isoform 2 of Serine/threonine-protein kinase 33 OS=Homo sapiens GN=STK33 0.985044 18.2358 0.632823 2.47709 0.073148 48.509 0 0 0.985044 18.2358 2.04489E-12 174.73 0.864788 10.0175 0.0026916 83.905 1 S FDMCSSSFTSSKL GSK3 0.081 2.04489E-12 174.73 _DNFDMCSSpSFTSSK_ DNFDMCSSS(0.985)FT(0.015)SSK DNFDMCS(-45.05)S(-38.55)S(18.24)FT(-18.24)S(-66.78)S(-66.78)K 9 2 846.7995 -0.52511 174430 29974 0 0 0 0 97322 47131 2206 1551 441 441 5875 6700 57933 35201 Mix4_TiO2_1_4 5631 57933 35201 Mix4_TiO2_1_4 5631 Q9BYT3 Q9BYT3 Q9BYT3 >sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo sapiens GN=STK33 PE=1 SV=1 0.741715 7.74196 0.741715 7.74196 0.000115385 91.141 0 0 0.328797 0 0.0306766 61.791 0 0 1 S PDANYTSDEEEEK CK2 0.117 0.000115385 91.141 _SYQPWGNVPDANYTpSDEEEEKQSTAYEK_ SYQPWGNVPDANY(0.125)T(0.125)S(0.742)DEEEEKQS(0.004)T(0.004)AY(0.001)EK S(-86.95)Y(-86.95)QPWGNVPDANY(-7.74)T(-7.74)S(7.74)DEEEEKQS(-22.67)T(-22.67)AY(-29.84)EK 15 3 1115.7963 0.078156 311850 311850 0 0 0 0 0 0 2207 1552 920 920 623 718 5944 3482 Mix4_InSol_TiO2_1 4120 5944 3482 Mix4_InSol_TiO2_1 4120 Q9BYX2;Q9BYX2-2;Q9BYX2-4;Q9BYX2-5;Q9BYX2-6 Q9BYX2 Q9BYX2 >sp|Q9BYX2|TBD2A_HUMAN TBC1 domain family member 2A OS=Homo sapiens GN=TBC1D2 PE=1 SV=3;>sp|Q9BYX2-2|TBD2A_HUMAN Isoform PARIS-1 of TBC1 domain family member 2A OS=Homo sapiens GN=TBC1D2;>sp|Q9BYX2-4|TBD2A_HUMAN Isoform 4 of TBC1 domain family member 2A OS 0.999999 60.2658 0.999999 60.2658 0.00121687 89.384 0 0 1 S VSEGCASEDEVEG CK2 0.117 0.00121687 89.384 _AVSEGCApSEDEVEGEA_ AVSEGCAS(1)EDEVEGEA AVS(-60.27)EGCAS(60.27)EDEVEGEA 8 2 859.80858 0.60633 54387 0 0 0 0 0 54387 0 2208 1553 927 927 178 207 1898 1274 Mix4_TiO2_1_1 3386 1898 1274 Mix4_TiO2_1_1 3386 Q9BZ29-4;Q9BZ29;Q9BZ29-5;Q9BZ29-3 Q9BZ29-4 Q9BZ29-4 >sp|Q9BZ29-4|DOCK9_HUMAN Isoform 4 of Dedicator of cytokinesis protein 9 OS=Homo sapiens GN=DOCK9;>sp|Q9BZ29|DOCK9_HUMAN Dedicator of cytokinesis protein 9 OS=Homo sapiens GN=DOCK9 PE=1 SV=2;>sp|Q9BZ29-5|DOCK9_HUMAN Isoform 2 of Dedicator of cytokinesis pr 0.99928 31.441 0.99928 31.441 0.0216689 55.381 0.993749 25.0233 0.257482 25.023 1 S AEPYVASEYKTVH 0.0216689 55.381 _AEPYVApSEYK_ AEPYVAS(0.999)EY(0.001)K AEPY(-55.38)VAS(31.44)EY(-31.44)K 7 2 618.76284 0.7927 262150 46753 0 0 215400 0 0 0 2209 1555 578 578 1328 1497 12426 7591 Mix4_InSol_TiO2_1 4350 12426 7591 Mix4_InSol_TiO2_1 4350 Q9BZE4 Q9BZE4 Q9BZE4 >sp|Q9BZE4|NOG1_HUMAN Nucleolar GTP-binding protein 1 OS=Homo sapiens GN=GTPBP4 PE=1 SV=3 1 66.985 0 0 1 66.985 0.00567412 66.985 0 0 1 S RTPRDVSGLRDVK CAMK2 0.042 0.00567412 66.985 _DVpSGLRDVK_ DVS(1)GLRDVK DVS(66.99)GLRDVK 3 2 534.7579 -0.71987 65882 0 0 0 0 0 65882 0 2210 1559 212 212 3466 3912 32650 20242 Mix4_TiO2_1_5 5260 32651 20243 Mix4_TiO2_Reinj_1_3 6131 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.325542 0 0.325542 0 0.00219328 81.742 0.00403856 -23.7362 0.00109967 90.326 0.0121575 -18.7801 0.801995 18.78 0.052082 -12.2987 0.0977606 49.107 1 S SVRLGTSESLPCT NEK6 0.076 0.00109967 90.326 _LGpTSESLPCTAEELSR_ LGT(0.326)S(0.326)ES(0.279)LPCT(0.035)AEELS(0.035)R LGT(0)S(0)ES(-0.68)LPCT(-9.66)AEELS(-9.66)R 4 2 915.40298 1.2467 0 0 0 0 0 0 0 0 2211 1559 214 214 3466 3912 32649 20241 Mix4_TiO2_1_3 5350 32651 20243 Mix4_TiO2_Reinj_1_3 6131 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.960995 16.426 0.960995 16.426 0.00219328 81.742 0.954649 14.6198 0.00109967 90.326 0.918028 13.0485 0.801995 18.78 0.88422 12.2987 0.0977606 49.107 1 S RLGTSESLPCTAE 0.00109967 90.326 _LGTSEpSLPCTAEELSR_ LGT(0.022)S(0.016)ES(0.961)LPCT(0.001)AEELSR LGT(-16.43)S(-17.65)ES(16.43)LPCT(-31.87)AEELS(-81.74)R 6 2 915.40298 0.16797 803860 190920 0 0 445620 0 35073 132250 2212 1559 197 197 3747;4960;5027 4227;5640;5641;5718 47765 29199 Mix4_TiO2_1_3 3291 47764 29185 Mix4_TiO2_1_3 3274 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.996632 25.3157 0.996632 25.3157 3.41972E-16 191.08 0.320272 0 0.0160506 67.554 0 0 0.987362 19.4955 2.93347E-09 151.96 0.593096 5.78357 0.0104332 72.874 0.861836 8.11618 1.6225E-06 120.42 0.981473 17.4899 3.24548E-09 151.45 1 S ARKRRLSSTSLAS CAMK2;PKA;PKA/AKT 0.00111111 3.41972E-16 191.08 _RLpSSTSLASGHSVR_ RLS(0.997)S(0.003)TSLASGHSVR RLS(25.32)S(-25.32)T(-33.6)S(-57.92)LAS(-126.12)GHS(-151.45)VR 3 2 769.37776 -0.081977 39076000 3545200 0 0 18835000 16591 10465000 6214500 2213 1559 198 198 3747;4960;5027 4227;5640;5641;5718 35425 21890 Mix4_TiO2_1_3 3060 47764 29185 Mix4_TiO2_1_3 3274 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.848391 7.52281 0.848391 7.52281 3.41972E-16 191.08 0.179727 -2.50905 0.0160506 67.554 0 0 0.824712 6.746 2.93347E-09 151.96 0.200069 -3.00653 0.0104332 72.874 0.713799 8.81603 0.208625 35.759 0.725169 8.78243 3.24548E-09 151.45 1 S RKRRLSSTSLASG CAMK2 0.042 3.41972E-16 191.08 _LSpSTSLASGHSVR_ LS(0.15)S(0.848)T(0.001)SLASGHSVR LS(-7.52)S(7.52)T(-28.02)S(-36.45)LAS(-69.58)GHS(-79.79)VR 3 2 691.32721 0.011211 284200 72391 0 0 172900 0 0 38906 2214 1559 200 200 3747;4960;5027 4227;5640;5641;5718 47764 29185 Mix4_TiO2_1_3 3274 47764 29185 Mix4_TiO2_1_3 3274 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.802113 7.28061 0.802113 7.28061 3.41972E-16 191.08 0.320272 0 0.0160506 67.554 0 0 0.618958 1.62474 3.41628E-05 115.29 0.200069 -3.00653 0.0104332 72.874 0.198604 -9.71065 0.208625 35.759 0.240447 -8.57013 0.801366 12.405 1 S RRLSSTSLASGHS CK1 0.081 3.41972E-16 191.08 _RLSSTpSLASGHSVR_ RLS(0.15)S(0.004)T(0.043)S(0.802)LASGHSVR RLS(-7.28)S(-22.54)T(-12.67)S(7.28)LAS(-127.35)GHS(-188.96)VR 6 3 513.25427 -0.11155 1200100 1200100 0 0 0 0 0 0 2215 1559 206 206 3747;4960;5027 4227;5640;5641;5718 47824 29269 Mix4_TiO2_1_5 3351 47831 29276 Mix4_TiO2_Reinj_1_5 4102 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.99913 31.0181 0.99913 31.0181 0.014811 68.728 5.62543E-08 -67.5536 0.0160506 67.554 0 0 0.997485 26.5848 3.41628E-05 115.29 0.0205202 -14.6094 0.0104332 72.874 0.999008 35.6042 0.208625 35.759 0.1299 -12.4053 0.801366 12.405 2 S SLASGHSVRLGTS CK1 0.081 3.41628E-05 115.29 _RLpSSTSLASGHpSVR_ RLS(0.491)S(0.17)T(0.17)S(0.17)LASGHS(0.999)VR RLS(4.61)S(-4.61)T(-4.61)S(-4.61)LAS(-36.18)GHS(31.02)VR 12 3 539.90971 0.5985 1931900 262010 0 0 1488000 0 181970 0 2216 1559 710 710 5864 6687 57852 35173 Mix4_TiO2_Reinj_1_5 8425 57852 35173 Mix4_TiO2_Reinj_1_5 8425 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 1 65.9359 0.999736 35.8624 9.63958E-17 148.33 1 65.9359 4.45851E-24 170.24 0 0 0 0 1 S EKSFRRSVVGTPA AURORA;AURORA-1;CK1;NIMA;PKA 0.001741464 4.45851E-24 170.24 _pSVVGTPAYLAPEVLLNQGYNR_ S(1)VVGTPAYLAPEVLLNQGYNR S(65.94)VVGT(-65.94)PAY(-107.82)LAPEVLLNQGY(-170.24)NR 1 3 781.05778 0.06799 1573300 15.285 446830 0 0 1126500 0 0 0 2217 1560 602 602 4804 5454 45790 28000 Mix4_TiO2_Reinj_1_5 8258 45790 28000 Mix4_TiO2_Reinj_1_5 8258 Q9BZQ8 Q9BZQ8 Q9BZQ8 >sp|Q9BZQ8|NIBAN_HUMAN Protein Niban OS=Homo sapiens GN=FAM129A PE=1 SV=1 0.999994 52.437 0.957178 14.3353 0.00103372 90.906 0.999994 52.437 9.15687E-18 142.44 1 S SPARRASAILPGV CAMK2;PKA 0.004788 9.15687E-18 142.44 _RApSAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAK_ RAS(1)AILPGVLGSETLSNEVFQESEEEKQPEVPSSLAK RAS(52.44)AILPGVLGS(-52.44)ET(-64.58)LS(-88.45)NEVFQES(-123.35)EEEKQPEVPS(-131.91)S(-131.91)LAK 3 4 1009.7504 0.19813 1317100 217860 0 0 1099200 0 0 0 2218 1561 380 380 2145 2430 19731 12069 Mix4_TiO2_Reinj_1_3 4583 19727 12065 Mix4_TiO2_1_5 3880 Q9C0B5;Q9C0B5-2 Q9C0B5 Q9C0B5 >sp|Q9C0B5|ZDHC5_HUMAN Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 PE=1 SV=2;>sp|Q9C0B5-2|ZDHC5_HUMAN Isoform 2 of Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 1 67.9529 1 71.5393 1.65525E-05 114.82 0 0 1 67.9529 2.61622E-05 112.83 0 0 0 0 0 0 1 S KLSRGDSLKEPTS CAMK2;CHK1;CHK1/2;CK1;CK2;PKD 0.003192 1.65525E-05 114.82 _GDpSLKEPTSIAESSR_ GDS(1)LKEPTSIAESSR GDS(67.95)LKEPT(-67.95)S(-72.88)IAES(-72.88)S(-72.88)R 3 2 828.87746 0.29088 1483600 392980 0 0 1090600 0 0 0 2219 1561 554 554 3575 4030 33650 20731 Mix4_TiO2_Reinj_1_3 5462 33650 20731 Mix4_TiO2_Reinj_1_3 5462 Q9C0B5;Q9C0B5-2 Q9C0B5 Q9C0B5 >sp|Q9C0B5|ZDHC5_HUMAN Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 PE=1 SV=2;>sp|Q9C0B5-2|ZDHC5_HUMAN Isoform 2 of Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 0.999886 39.4749 0.999886 39.4749 0.0250807 73.843 1 S EKLLRQSPPLPGR NEK6;PKA;Proline-directed 0.042 0.0250807 73.843 _LLRQpSPPLPGREEEPGLGDSGIQSTPGSGHAPR_ LLRQS(1)PPLPGREEEPGLGDSGIQSTPGSGHAPR LLRQS(39.47)PPLPGREEEPGLGDS(-39.47)GIQS(-62.37)T(-66.1)PGS(-73.84)GHAPR 5 4 868.92968 -0.058835 1170400 0 0 0 1170400 0 0 0 2220 1561 693 693 5438 6189 53045 32424 Mix4_TiO2_1_5 3984 53044 32423 Mix4_TiO2_1_3 3962 Q9C0B5;Q9C0B5-2 Q9C0B5 Q9C0B5 >sp|Q9C0B5|ZDHC5_HUMAN Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 PE=1 SV=2;>sp|Q9C0B5-2|ZDHC5_HUMAN Isoform 2 of Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 0.493514 0 0.493514 0 3.75367E-06 101.43 0 0 0.0422641 -12.77 0.000676836 87.339 0 0 0 0 1 S PGQPPLSSPTRGG 3.75367E-06 101.43 _SLGSASPGPGQPPLpSSPTR_ SLGSASPGPGQPPLS(0.494)S(0.494)PT(0.013)R S(-57.89)LGS(-57.89)AS(-57.89)PGPGQPPLS(0)S(0)PT(-15.8)R 15 2 936.9462 0.64186 0 0 0 0 0 0 0 0 2221 1561 694 694 5438 6189 53044 32423 Mix4_TiO2_1_3 3962 53044 32423 Mix4_TiO2_1_3 3962 Q9C0B5;Q9C0B5-2 Q9C0B5 Q9C0B5 >sp|Q9C0B5|ZDHC5_HUMAN Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 PE=1 SV=2;>sp|Q9C0B5-2|ZDHC5_HUMAN Isoform 2 of Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 0.827197 7.69855 0.827197 7.69855 3.75367E-06 101.43 0 0 0.820697 7.52475 0.000676836 87.339 0 0 0 0 1 S GQPPLSSPTRGGV CDK1;CDK2;Polo box;Proline-directed 0.00405 3.75367E-06 101.43 _SLGSASPGPGQPPLSpSPTR_ SLGSASPGPGQPPLS(0.032)S(0.827)PT(0.141)R S(-101.43)LGS(-101.43)AS(-96.96)PGPGQPPLS(-14.09)S(7.7)PT(-7.7)R 16 2 936.9462 0.33683 624510 145810 0 0 478700 0 0 0 2222 1563 872 872 715 820 6888 4091 Mix4_TiO2_Reinj_1_1 4710 6888 4091 Mix4_TiO2_Reinj_1_1 4710 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 0.967815 15.7052 0 0 0.967815 15.7052 0.023002 59.658 0.655004 7.61629 0.228642 40.6 0.955649 19.0948 0.589184 33.233 1 S EFGKRDSLGTYSS AURORA;AURORA-1;AURORA-A;PKA 0.006142092 0.023002 59.658 _DAELQDQEFGKRDpSLGTYSSR_ DAELQDQEFGKRDS(0.968)LGT(0.026)Y(0.005)S(0.001)SR DAELQDQEFGKRDS(15.71)LGT(-15.71)Y(-22.8)S(-30.37)S(-36.95)R 14 3 828.03425 -0.22817 736300 0 0 0 301380 0 230050 204870 2223 1563 494 494 3354 3793;3794 31604 19548 Mix4_TiO2_Reinj_1_1 7725 31604 19548 Mix4_TiO2_Reinj_1_1 7725 Q9C0C2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3 0.809026 7.36419 0 0 0 0 0.809026 7.36419 2.56501E-12 125.72 2 S GVWRLDSPPPSPI CAMK2;CHK1;GSK3;PKD;Proline-directed 0.020748 2.56501E-12 125.72 _LDpSPPPSPIpTEASEAAEAAEAGNLAVSSR_ LDS(0.809)PPPS(0.222)PIT(0.804)EAS(0.165)EAAEAAEAGNLAVSSR LDS(7.36)PPPS(-7.36)PIT(8.47)EAS(-8.47)EAAEAAEAGNLAVS(-125.72)S(-125.72)R 3 3 999.77572 0.33183 659030 0 0 0 659030 0 0 0 2224 1563 504 504 3354 3793;3794 31606 19550 Mix4_TiO2_Reinj_1_1 7896 31606 19550 Mix4_TiO2_Reinj_1_1 7896 Q9C0C2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3 0.657258 5.63119 0 0 0 0 0.657258 5.63119 1.81488E-18 145.01 1 S SPITEASEAAEAA 1.81488E-18 145.01 _LDSPPPSPITEApSEAAEAAEAGNLAVSSR_ LDS(0.144)PPPS(0.019)PIT(0.18)EAS(0.657)EAAEAAEAGNLAVSSR LDS(-6.6)PPPS(-15.33)PIT(-5.63)EAS(5.63)EAAEAAEAGNLAVS(-145.01)S(-145.01)R 13 3 973.12027 0.1444 473060 0 0 0 473060 0 0 0 2225 1563 1666 1666 4289 4880 40810 25111 Mix4_TiO2_Reinj_1_5 3107 40810 25111 Mix4_TiO2_Reinj_1_5 3107 Q9C0C2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3 1 146.408 1 79.8029 0.00467028 79.803 1 146.408 2.95117E-06 146.41 1 128.958 2.54296E-05 128.96 1 128.403 2.67423E-05 128.4 1 S LRPRNRSAEEGEL CAMK2;CK2;PKA/AKT 0.001764 2.95117E-06 146.41 _NRpSAEEGELAESK_ NRS(1)AEEGELAESK NRS(146.41)AEEGELAES(-146.41)K 3 2 750.32232 0.69198 503400 57713 0 0 210830 0 117130 117720 2226 1563 836 836 5615 6398 54873 33597 Mix4_TiO2_1_1 5492 54873 33597 Mix4_TiO2_1_1 5492 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 1 130.395 1 130.395 5.47987E-05 130.4 0 0 1 S QLGTQRSQEADVQ 5.47987E-05 130.4 _pSQEADVQDWEFR_ S(1)QEADVQDWEFR S(130.4)QEADVQDWEFR 1 2 795.31703 -1.631 22237 22237 0 0 0 0 0 0 2227 1563 672 672 5955 6792 58831 35711 Mix4_TiO2_Reinj_1_1 3521 58828 35708 Mix4_InSol_Tio2_Reinj_1 4285 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 1 68.0467 0.999999 67.6151 0.00026071 89.824 0 0 1 68.0467 0.00028161 89.099 0.999993 51.4992 0.000218454 91.288 0.999921 41.0265 6.187E-07 105.89 1 S QDLCRASPEPPGP PKA;Proline-directed 0.042 6.187E-07 105.89 _TEAQDLCRApSPEPPGPESSSR_ TEAQDLCRAS(1)PEPPGPESSSR T(-68.05)EAQDLCRAS(68.05)PEPPGPES(-71.85)S(-71.85)S(-71.85)R 10 3 784.33717 0.58059 912190 81069 0 0 289510 0 325930 215680 2228 1563 1620 1620 6542 7485 66065 40540 Mix4_TiO2_1_1 3454 66065 40540 Mix4_TiO2_1_1 3454 Q9C0C2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3 0.999988 49.3459 0.999988 49.3459 0.0854252 49.346 2 S RASRVPSSDEEVV CAMK2;CK1;CK2 0.042 0.0854252 49.346 _VPpSpSDEEVVEEPQSR_ VPS(1)S(1)DEEVVEEPQSR VPS(49.35)S(49.35)DEEVVEEPQS(-49.35)R 3 2 923.86082 0.68477 24669 24669 0 0 0 0 0 0 2229 1563 1621 1621 6542 7485 66065 40540 Mix4_TiO2_1_1 3454 66065 40540 Mix4_TiO2_1_1 3454 Q9C0C2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3 0.999988 49.3459 0.999988 49.3459 0.0854252 49.346 2 S ASRVPSSDEEVVE CK2 0.117 0.0854252 49.346 _VPpSpSDEEVVEEPQSR_ VPS(1)S(1)DEEVVEEPQSR VPS(49.35)S(49.35)DEEVVEEPQS(-49.35)R 4 2 923.86082 0.68477 24669 24669 0 0 0 0 0 0 2230 1563 1138 1138 6595 7547 66862 41004 Mix4_TiO2_1_1 2410 66862 41004 Mix4_TiO2_1_1 2410 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 0.473601 0 0.473601 0 0.0646827 44.281 0.36815 -1.81272 0.0742608 41.44 0 0 1 S VSGAGFSPSSKME Proline-directed 0.05 0.0646827 44.281 _VSGAGFpSPSSK_ VSGAGFS(0.474)PS(0.053)S(0.474)K VS(-44.28)GAGFS(0)PS(-9.53)S(0)K 7 2 552.24208 -0.011502 0 0 0 0 0 0 0 0 2231 1563 1141 1141 6595 7547 66861 41003 Mix4_InSol_TiO2_1 3705 66862 41004 Mix4_TiO2_1_1 2410 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 0.558853 1.81272 0.473601 0 0.0646827 44.281 0.558853 1.81272 0.0742608 41.44 0 0 1 S AGFSPSSKMEGGH CK1;CK2 0.081 0.0646827 44.281 _VSGAGFSPSpSK_ VSGAGFS(0.368)PS(0.073)S(0.559)K VS(-41.44)GAGFS(-1.81)PS(-8.84)S(1.81)K 10 2 552.24208 1.8348 30628 0 0 0 0 0 30628 0 2232 1563 691 691 6685 7654 67787 41585 Mix4_TiO2_Reinj_1_1 7369 67787 41585 Mix4_TiO2_Reinj_1_1 7369 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 0.99917 30.8052 0.996578 24.642 0.174097 40.402 0.99917 30.8052 0.00124469 86.976 0 0 1 S LDDLLASPPPSGG GSK3;NEK6;Proline-directed 0.05 0.00124469 86.976 _WLDDLLApSPPPSGGGAR_ WLDDLLAS(0.999)PPPS(0.001)GGGAR WLDDLLAS(30.81)PPPS(-30.81)GGGAR 8 2 894.91946 0.9677 236390 51476 0 0 184910 0 0 0 2233 1563 601 601 6721 7694 68161 41788 Mix4_TiO2_Reinj_1_1 5727 68161 41788 Mix4_TiO2_Reinj_1_1 5727 Q9C0C2;Q9C0C2-2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3;>sp|Q9C0C2-2|TB182_HUMAN Isoform 2 of 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 1 101.55 1 65.9846 4.94807E-21 157.34 0 0 1 101.55 1.38871E-31 202.37 0 0 1 S PLAGQESPLPLAT Proline-directed 0.05 1.38871E-31 202.37 _YESQEPLAGQEpSPLPLATR_ YESQEPLAGQES(1)PLPLATR Y(-176.48)ES(-146.33)QEPLAGQES(101.55)PLPLAT(-101.55)R 12 3 722.67534 0.2276 704160 84043 0 0 620110 0 0 0 2234 1564 549 549 3390 3831 31938 19748 Mix4_TiO2_Reinj_1_5 4163 31938 19748 Mix4_TiO2_Reinj_1_5 4163 Q9C0C7-5;Q9C0C7;Q9C0C7-3;Q9C0C7-2;Q9C0C7-4 Q9C0C7-5 Q9C0C7-5 >sp|Q9C0C7-5|AMRA1_HUMAN Isoform 5 of Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=AMBRA1;>sp|Q9C0C7|AMRA1_HUMAN Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens GN=AMBRA1 PE=1 SV=2;>sp|Q9C0C7-3|AM 0.998894 29.5566 0 0 0.998894 29.5566 0.000433043 104.96 1 S ELSSSASPQEERT CK1;CK2;Proline-directed 0.05 0.000433043 104.96 _LELSSSApSPQEER_ LELSSS(0.001)AS(0.999)PQEER LELS(-89.28)S(-67.01)S(-29.56)AS(29.56)PQEER 8 2 756.83252 0.5813 83487 0 0 0 83487 0 0 0 2235 1565 521 521 2641 3004 24626 15260 Mix4_TiO2_1_5 3606 24632 15269 Mix4_TiO2_Reinj_1_5 4309 Q9C0E2 Q9C0E2 Q9C0E2 >sp|Q9C0E2|XPO4_HUMAN Exportin-4 OS=Homo sapiens GN=XPO4 PE=1 SV=2 0.999947 42.7989 0.999947 42.7989 9.48475E-13 145.93 0 0 0.999474 32.9444 2.8115E-35 233.46 0.998847 29.7382 7.57813E-06 103.74 0.991497 20.6762 2.34579E-06 113.65 1 S QQQLLASPGSSTV GSK3;NEK6;Proline-directed 0.05 2.8115E-35 233.46 _HQQQLLApSPGSSTVDNK_ HQQQLLAS(1)PGSSTVDNK HQQQLLAS(42.8)PGS(-42.8)S(-74.86)T(-74.86)VDNK 8 3 630.62995 0.67898 6148200 1377000 0 0 4043200 0 413180 314790 2236 1565 525 525 2641 3004 24633 15271 Mix4_TiO2_Reinj_1_6 3680 24632 15269 Mix4_TiO2_Reinj_1_5 4309 Q9C0E2 Q9C0E2 Q9C0E2 >sp|Q9C0E2|XPO4_HUMAN Exportin-4 OS=Homo sapiens GN=XPO4 PE=1 SV=2 0.280495 0 0.0922222 -8.94503 9.48475E-13 145.93 0 0 0.280495 0 2.8115E-35 233.46 0.099822 -8.5292 7.57813E-06 103.74 0.0666172 -9.27733 2.34579E-06 113.65 1 S LASPGSSTVDNKM CK1;CK2 0.117 2.8115E-35 233.46 _HQQQLLASPGpSSTVDNK_ HQQQLLAS(0.159)PGS(0.28)S(0.28)T(0.28)VDNK HQQQLLAS(-2.48)PGS(0)S(0)T(0)VDNK 12 3 630.62995 -1.0468 0 0 0 0 0 0 0 0 2237 1566 384 384 483 548 4515 2730 Mix4_TiO2_1_4 1236 4515 2730 Mix4_TiO2_1_4 1236 Q9C0E8;Q9C0E8-2;Q9C0E8-3 Q9C0E8 Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens GN=LNP PE=1 SV=2;>sp|Q9C0E8-2|LNP_HUMAN Isoform 2 of Protein lunapark OS=Homo sapiens GN=LNP;>sp|Q9C0E8-3|LNP_HUMAN Isoform 3 of Protein lunapark OS=Homo sapiens GN=LNP 0.999624 34.2408 0.999624 34.2408 0.146239 34.241 1 S QVIEKASDSEEPE CK2 0.117 0.146239 34.241 _ApSDSEEPEEK_ AS(1)DSEEPEEK AS(34.24)DS(-34.24)EEPEEK 2 2 600.71883 1.2081 15818 15818 0 0 0 0 0 0 2238 1566 177 177 4164;4165 4741;4742;4743 39704 24513 Mix4_TiO2_Reinj_1_6 4439 39702 24509 Mix4_TiO2_Reinj_1_4 5099 Q9C0E8;Q9C0E8-2;Q9C0E8-3 Q9C0E8 Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens GN=LNP PE=1 SV=2;>sp|Q9C0E8-2|LNP_HUMAN Isoform 2 of Protein lunapark OS=Homo sapiens GN=LNP;>sp|Q9C0E8-3|LNP_HUMAN Isoform 3 of Protein lunapark OS=Homo sapiens GN=LNP 0.955129 13.2834 0.57623 1.34589 1.09501E-17 139.75 0.945137 12.6922 0.00025167 88.201 0.955129 13.2834 6.88165E-18 146.06 0.775777 5.39105 4.18529E-07 104.83 0.869283 9.48465 1.44624E-07 113.52 1 S AAQRNLSPTPASP CAMK2;Proline-directed 0.042 6.88165E-18 146.06 _NLpSPTPASPNQGPPPQVPVSPGPPK_ NLS(0.955)PT(0.045)PASPNQGPPPQVPVSPGPPK NLS(13.28)PT(-13.28)PAS(-45.81)PNQGPPPQVPVS(-121.32)PGPPK 3 3 847.42301 -0.60132 1849800 28066 59783 0 974180 0 182610 605180 2239 1566 182 182 4164;4165 4741;4742;4743 39715 24514 Mix4_TiO2_1_4 4777 39715 24514 Mix4_TiO2_1_4 4777 Q9C0E8;Q9C0E8-2;Q9C0E8-3 Q9C0E8 Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens GN=LNP PE=1 SV=2;>sp|Q9C0E8-2|LNP_HUMAN Isoform 2 of Protein lunapark OS=Homo sapiens GN=LNP;>sp|Q9C0E8-3|LNP_HUMAN Isoform 3 of Protein lunapark OS=Homo sapiens GN=LNP 0.994983 23.0126 0.994983 23.0126 0.000448867 79.855 0.00401512 -23.718 0.00025167 88.201 0.015861 -16.9339 6.88165E-18 146.06 0.220042 -2.4845 4.18529E-07 104.83 0.0209133 -16.4823 1.44624E-07 113.52 2 S LSPTPASPNQGPP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000448867 79.855 _NLSPTPApSPNQGPPPQVPVpSPGPPK_ NLSPT(0.005)PAS(0.995)PNQGPPPQVPVS(1)PGPPK NLS(-43.47)PT(-23.01)PAS(23.01)PNQGPPPQVPVS(62.22)PGPPK 8 3 874.07845 -0.016379 193370 193370 0 0 0 0 0 0 2240 1566 194 194 4164;4165 4741;4742;4743 39702 24509 Mix4_TiO2_Reinj_1_4 5099 39702 24509 Mix4_TiO2_Reinj_1_4 5099 Q9C0E8;Q9C0E8-2;Q9C0E8-3 Q9C0E8 Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens GN=LNP PE=1 SV=2;>sp|Q9C0E8-2|LNP_HUMAN Isoform 2 of Protein lunapark OS=Homo sapiens GN=LNP;>sp|Q9C0E8-3|LNP_HUMAN Isoform 3 of Protein lunapark OS=Homo sapiens GN=LNP 1 116.346 1 123.737 1.09501E-17 139.75 1.4303E-09 -88.2007 0.00025167 88.201 1 116.346 6.88165E-18 146.06 0.000152186 -34.0858 4.18529E-07 104.83 0.0241422 -15.5638 1.44624E-07 113.52 1 S PPQVPVSPGPPKD ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 6.88165E-18 146.06 _NLSPTPASPNQGPPPQVPVpSPGPPK_ NLSPTPASPNQGPPPQVPVS(1)PGPPK NLS(-146.06)PT(-134.1)PAS(-116.35)PNQGPPPQVPVS(116.35)PGPPK 20 3 847.42301 -0.68808 6280500 1591900 0 0 4688600 0 0 0 2241 1567 604 604 209 241 2150 1413 Mix4_TiO2_Reinj_1_5 5351 2150 1413 Mix4_TiO2_Reinj_1_5 5351 Q9C0H5 Q9C0H5 Q9C0H5 >sp|Q9C0H5|RHG39_HUMAN Rho GTPase-activating protein 39 OS=Homo sapiens GN=ARHGAP39 PE=1 SV=2 1 134.188 0 0 1 134.188 3.14176E-07 134.19 1 S PVVRAFSEDEALA CAMK2;CHK1;CK2;PKD 0.020748 3.14176E-07 134.19 _AFpSEDEALAQQENR_ AFS(1)EDEALAQQENR AFS(134.19)EDEALAQQENR 3 2 844.35161 0.24409 132420 0 0 0 132420 0 0 0 2242 1567 690 690 3165 3593 30034 18687 Mix4_TiO2_Reinj_1_5 5603 30034 18687 Mix4_TiO2_Reinj_1_5 5603 Q9C0H5 Q9C0H5 Q9C0H5 >sp|Q9C0H5|RHG39_HUMAN Rho GTPase-activating protein 39 OS=Homo sapiens GN=ARHGAP39 PE=1 SV=2 0.826902 7.74387 0 0 0.826902 7.74387 0.00139901 91.71 1 S TLRKPSSETDIEN CHK1;CK2;PKD 0.020748 0.00139901 91.71 _KPSpSETDIENWASK_ KPS(0.139)S(0.827)ET(0.034)DIENWASK KPS(-7.74)S(7.74)ET(-13.85)DIENWAS(-83.61)K 4 2 836.36672 -0.534 75817 0 0 0 75817 0 0 0 2243 1567 407 407 4647 5273 44026 26985 Mix4_TiO2_1_5 4170 44026 26985 Mix4_TiO2_1_5 4170 Q9C0H5 Q9C0H5 Q9C0H5 >sp|Q9C0H5|RHG39_HUMAN Rho GTPase-activating protein 39 OS=Homo sapiens GN=ARHGAP39 PE=1 SV=2 0.866468 8.12172 0.866468 8.12172 0.0267051 58.675 0 0 0 0 1 S VEQAGSSPKLRAG CDK1;Polo box;Proline-directed 0.00405 0.0267051 58.675 _QLVYVEQAGSpSPK_ QLVYVEQAGS(0.134)S(0.866)PK QLVY(-58.68)VEQAGS(-8.12)S(8.12)PK 11 2 743.35289 0.8217 24365 24365 0 0 0 0 0 0 2244 1570 82 82 418;2970;2971 477;478;3378;3379 28295 17576 Mix4_TiO2_Reinj_1_5 3069 3951 2352 Mix4_TiO2_Reinj_1_5 2999 Q9GZR7 Q9GZR7 Q9GZR7 >sp|Q9GZR7|DDX24_HUMAN ATP-dependent RNA helicase DDX24 OS=Homo sapiens GN=DDX24 PE=1 SV=1 1 108.807 1 59.2287 4.16971E-16 152.76 1 108.807 2.18632E-31 195.39 0 0 1 S RKAQAVSEEEEEE CK2 0.117 2.18632E-31 195.39 _KAQAVpSEEEEEEEGK_ KAQAVS(1)EEEEEEEGK KAQAVS(108.81)EEEEEEEGK 6 2 886.36712 0.029223 127390 54383 0 0 73005 0 0 0 2245 1570 92 92 418;2971 477;478;3379 3948 2349 Mix4_TiO2_1_5 2475 3951 2352 Mix4_TiO2_Reinj_1_5 2999 Q9GZR7 Q9GZR7 Q9GZR7 >sp|Q9GZR7|DDX24_HUMAN ATP-dependent RNA helicase DDX24 OS=Homo sapiens GN=DDX24 PE=1 SV=1 0.333332 0 0.333332 0 4.16971E-16 152.76 0.229475 -4.50108 2.18632E-31 195.39 0 0 1 S EEEEGKSSSPKKK 2.18632E-31 195.39 _AQAVSEEEEEEEGKpSSSPK_ AQAVSEEEEEEEGKS(0.333)S(0.333)S(0.333)PK AQAVS(-50.19)EEEEEEEGKS(0)S(0)S(0)PK 15 3 710.63012 0.4954 0 0 0 0 0 0 0 0 2246 1570 93 93 418;2971 477;478;3379 3949 2350 Mix4_TiO2_1_5 2491 3951 2352 Mix4_TiO2_Reinj_1_5 2999 Q9GZR7 Q9GZR7 Q9GZR7 >sp|Q9GZR7|DDX24_HUMAN ATP-dependent RNA helicase DDX24 OS=Homo sapiens GN=DDX24 PE=1 SV=1 0.499064 0 0.499064 0 4.16971E-16 152.76 0.492919 0.775684 0.911916 21.901 0 0 1 S EEEGKSSSPKKKI 2.18632E-31 195.39 _AQAVSEEEEEEEGKSpSSPK_ AQAVSEEEEEEEGKS(0.002)S(0.499)S(0.499)PK AQAVS(-152.76)EEEEEEEGKS(-24.26)S(0)S(0)PK 16 2 1065.4415 -0.20084 0 0 0 0 0 0 0 0 2247 1570 94 94 418;2971 477;478;3379 3951 2352 Mix4_TiO2_Reinj_1_5 2999 3951 2352 Mix4_TiO2_Reinj_1_5 2999 Q9GZR7 Q9GZR7 Q9GZR7 >sp|Q9GZR7|DDX24_HUMAN ATP-dependent RNA helicase DDX24 OS=Homo sapiens GN=DDX24 PE=1 SV=1 0.963008 14.3175 0.70239 6.37215 4.16971E-16 152.76 0.963008 14.3175 2.18632E-31 195.39 0 0 1 S EEGKSSSPKKKIK CDK1;CDK2;Polo box;Proline-directed 0.00405 2.18632E-31 195.39 _AQAVSEEEEEEEGKSSpSPK_ AQAVSEEEEEEEGKS(0.001)S(0.036)S(0.963)PK AQAVS(-155.88)EEEEEEEGKS(-28.51)S(-14.32)S(14.32)PK 17 2 1065.4415 -0.27474 398630 32908 0 0 365720 0 0 0 2248 1571 46 46 5741 6542 56419 34453 Mix4_TiO2_1_1 5196 56417 34451 Mix4_InSol_TiO2_1 6891 Q9GZU3 Q9GZU3 Q9GZU3 >sp|Q9GZU3|TM39B_HUMAN Transmembrane protein 39B OS=Homo sapiens GN=TMEM39B PE=2 SV=1 0.436308 0.620059 0.436308 0.620059 1.30933 25.763 0 0 0.391657 0.75793 0.116652 54.308 0.132914 -4.33637 1.08827 29.207 1 S RSRTRSSSGTGLS PKA 0.042 0.116652 54.308 _SpSSGTGLSSPPLATQTVVPLQHCK_ S(0.378)S(0.436)S(0.123)GT(0.049)GLS(0.001)S(0.001)PPLAT(0.009)QT(0.002)VVPLQHCK S(-0.62)S(0.62)S(-5.51)GT(-9.48)GLS(-25.76)S(-25.76)PPLAT(-16.7)QT(-23.3)VVPLQHCK 2 3 844.74364 0.568 0 0 0 0 0 0 0 0 2249 1573 457 457 1815 2048 16651 10023 Mix4_TiO2_1_3 7393 16650 10022 Mix4_TiO2_1_3 7260 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.720251 5.8035 0.720251 5.8035 4.93252E-26 156.8 0 0 1 S KPRQRESGYYSSP GSK3;PKA 0.042 4.93252E-26 156.8 _EpSGYYSSPEPSESGELLDAGDVFVSGDPK_ ES(0.72)GY(0.009)Y(0.009)S(0.189)S(0.052)PEPS(0.02)ES(0.001)GELLDAGDVFVSGDPK ES(5.8)GY(-19.21)Y(-19.21)S(-5.8)S(-11.42)PEPS(-15.51)ES(-28.9)GELLDAGDVFVS(-62.69)GDPK 2 2 1549.6555 0.63533 249300 1.4352 249300 0 0 0 0 0 0 2250 1573 461 461 1815 2048 16652 10024 Mix4_TiO2_1_5 7211 16650 10022 Mix4_TiO2_1_3 7260 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.37447 0 0.37447 0 4.93252E-26 156.8 0 0 1 S RESGYYSSPEPSE CK1;CK2 0.117 4.93252E-26 156.8 _ESGYYpSSPEPSESGELLDAGDVFVSGDPK_ ES(0.077)GY(0.077)Y(0.077)S(0.374)S(0.374)PEPS(0.019)ES(0.001)GELLDAGDVFVSGDPK ES(-6.87)GY(-6.87)Y(-6.87)S(0)S(0)PEPS(-12.94)ES(-24.5)GELLDAGDVFVS(-53.99)GDPK 6 3 1033.4394 0.92711 0 0 0 0 0 0 0 0 0 2251 1573 462 462 1815 2048 16652 10024 Mix4_TiO2_1_5 7211 16650 10022 Mix4_TiO2_1_3 7260 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.37447 0 0.37447 0 4.93252E-26 156.8 0 0 1 S ESGYYSSPEPSES GSK3;Polo box;Proline-directed 0.00405 4.93252E-26 156.8 _ESGYYpSSPEPSESGELLDAGDVFVSGDPK_ ES(0.077)GY(0.077)Y(0.077)S(0.374)S(0.374)PEPS(0.019)ES(0.001)GELLDAGDVFVSGDPK ES(-6.87)GY(-6.87)Y(-6.87)S(0)S(0)PEPS(-12.94)ES(-24.5)GELLDAGDVFVS(-53.99)GDPK 7 3 1033.4394 0.92711 0 0 0 0 0 0 0 0 0 2252 1573 468 468 1815 2048 16650 10022 Mix4_TiO2_1_3 7260 16650 10022 Mix4_TiO2_1_3 7260 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.884886 8.85804 0.884886 8.85804 4.93252E-26 156.8 0 0 1 S SPEPSESGELLDA 4.93252E-26 156.8 _ESGYYSSPEPSEpSGELLDAGDVFVSGDPK_ ESGYYSSPEPS(0.115)ES(0.885)GELLDAGDVFVSGDPK ES(-76.3)GY(-91.15)Y(-77.93)S(-56.37)S(-49.5)PEPS(-8.86)ES(8.86)GELLDAGDVFVS(-99.57)GDPK 13 3 1033.4394 0.347 146530 0.84355 146530 0 0 0 0 0 0 2253 1573 523 523 2066 2341 18940 11555 Mix4_TiO2_Reinj_1_3 8632 18938 11552 Mix4_TiO2_1_3 8041 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.945848 13.3806 0.333333 0 7.56397E-26 158.18 0.945848 13.3806 8.09821E-26 156.92 1 S APTTFGSLDELAP CK1;CK2 0.117 7.56397E-26 158.18 _FSQTALELAAPTTFGpSLDELAPPRPLAR_ FSQTALELAAPT(0.011)T(0.043)FGS(0.946)LDELAPPRPLAR FS(-46.47)QT(-46.47)ALELAAPT(-19.47)T(-13.38)FGS(13.38)LDELAPPRPLAR 16 4 763.14031 0.17307 302430 0 0 0 302430 0 0 0 2254 1573 553 553 4440 5050 42239 26000 Mix4_TiO2_Reinj_1_3 7964 42239 26000 Mix4_TiO2_Reinj_1_3 7964 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.897061 9.64905 0 0 0.897061 9.64905 0.00134745 78.779 1 S SILSSESFDQLDL CK1 0.081 0.00134745 78.779 _PSGAVSEDSILSSEpSFDQLDLPER_ PSGAVSEDS(0.001)ILS(0.005)S(0.097)ES(0.897)FDQLDLPER PS(-57.72)GAVS(-53.03)EDS(-28.98)ILS(-22.95)S(-9.65)ES(9.65)FDQLDLPER 15 3 886.73213 -0.70955 232600 0 0 0 232600 0 0 0 2255 1573 435 435 6584 7535 66762 40942 Mix4_TiO2_Reinj_1_3 7679 66762 40942 Mix4_TiO2_Reinj_1_3 7679 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 1 65.8295 0.999998 57.5463 9.73783E-08 103.7 1 65.8295 6.19204E-13 130.14 0.999988 49.1029 4.41894E-08 111.56 0 0 1 S LSPIPASPGQAAP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 6.19204E-13 130.14 _VSASAEGVQEDPPELSPIPApSPGQAAPLLPK_ VSASAEGVQEDPPELSPIPAS(1)PGQAAPLLPK VS(-100.54)AS(-100.54)AEGVQEDPPELS(-65.83)PIPAS(65.83)PGQAAPLLPK 21 3 1044.8549 0.20853 1901200 504860 0 0 1270800 0 125510 0 2256 1575 499 499 2962 3369;3370 28241 17554 Mix4_TiO2_1_5 2557 28241 17554 Mix4_TiO2_1_5 2557 Q9H0D6;Q9H0D6-2 Q9H0D6 Q9H0D6 >sp|Q9H0D6|XRN2_HUMAN 5'-3' exoribonuclease 2 OS=Homo sapiens GN=XRN2 PE=1 SV=1;>sp|Q9H0D6-2|XRN2_HUMAN Isoform XRN2b of 5'-3' exoribonuclease 2 OS=Homo sapiens GN=XRN2 0.998761 29.0633 0.998761 29.0633 3.20876E-06 113.61 0 0 1 S KRKAEDSDSEPEP CK2 0.117 3.20876E-06 113.61 _KAEDpSDSEPEPEDNVR_ KAEDS(0.999)DS(0.001)EPEPEDNVR KAEDS(29.06)DS(-29.06)EPEPEDNVR 5 2 948.87838 0.43233 24374 24374 0 0 0 0 0 0 2257 1575 501 501 2962 3369;3370 28243 17555 Mix4_TiO2_1_5 2574 28243 17555 Mix4_TiO2_1_5 2574 Q9H0D6;Q9H0D6-2 Q9H0D6 Q9H0D6 >sp|Q9H0D6|XRN2_HUMAN 5'-3' exoribonuclease 2 OS=Homo sapiens GN=XRN2 PE=1 SV=1;>sp|Q9H0D6-2|XRN2_HUMAN Isoform XRN2b of 5'-3' exoribonuclease 2 OS=Homo sapiens GN=XRN2 1 135.894 1 135.894 1.11483E-09 135.89 0 0 2 S KAEDSDSEPEPED CK2 0.117 1.11483E-09 135.89 _KAEDpSDpSEPEPEDNVR_ KAEDS(1)DS(1)EPEPEDNVR KAEDS(135.89)DS(135.89)EPEPEDNVR 7 2 988.86155 0.24437 141360 141360 0 0 0 0 0 0 2258 1575 448 448 4316 4909 40998 25212 Mix4_TiO2_Reinj_1_5 2422 40998 25212 Mix4_TiO2_Reinj_1_5 2422 Q9H0D6;Q9H0D6-2 Q9H0D6 Q9H0D6 >sp|Q9H0D6|XRN2_HUMAN 5'-3' exoribonuclease 2 OS=Homo sapiens GN=XRN2 PE=1 SV=1;>sp|Q9H0D6-2|XRN2_HUMAN Isoform XRN2b of 5'-3' exoribonuclease 2 OS=Homo sapiens GN=XRN2 0.999997 56.1147 0.999326 31.7711 0.0523802 50.273 0.999997 56.1147 0.0181552 59.963 1 S ALGSRNSPGSQVA CK1;PKA;Proline-directed 0.042 0.0181552 59.963 _NpSPGSQVASNPR_ NS(1)PGSQVASNPR NS(56.11)PGS(-56.11)QVAS(-59.96)NPR 2 2 647.2828 0.35243 460610 86893 0 0 373710 0 0 0 2259 1577 587 587 484;4809 549;5459 45876 28062 Mix4_TiO2_Reinj_1_5 6921 45876 28062 Mix4_TiO2_Reinj_1_5 6921 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.999202 30.9768 0.996593 24.7327 6.2808E-12 166.12 0.752732 9.60594 9.21503E-05 99.222 0.999202 30.9768 5.24717E-31 232.36 0.950943 13.7976 0.11576 43.91 0.724169 4.8404 3.4958E-05 111.02 0.990432 20.2818 1.24564E-05 115.66 1 S REGRRASDTSLTQ CAMK2;PKA;PKA/AKT 0.00111111 5.24717E-31 232.36 _RApSDTSLTQGIVAFR_ RAS(0.999)DT(0.001)SLTQGIVAFR RAS(30.98)DT(-30.98)S(-68.38)LT(-102.28)QGIVAFR 3 2 851.41963 -0.068882 15833000 1227800 11170 0 13488000 19491 175560 910300 2260 1577 590 590 484;4809 549;5459 45859 28035 Mix4_InSol_Tio2_Reinj_2 5377 45876 28062 Mix4_TiO2_Reinj_1_5 6921 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.553458 1.30984 0.391234 0 6.2808E-12 166.12 0.332117 0 9.21503E-05 99.222 0.101551 -8.94707 5.24717E-31 232.36 0.00821351 -20.6363 0.11576 43.91 0.333032 0 3.4958E-05 111.02 0.553458 1.30984 1.24564E-05 115.66 1 S RRASDTSLTQGIV CK1;PLK1 0.033462 5.24717E-31 232.36 _RASDTpSLTQGIVAFR_ RAS(0.034)DT(0.409)S(0.553)LT(0.003)QGIVAFR RAS(-12.15)DT(-1.31)S(1.31)LT(-22.08)QGIVAFR 6 2 851.41963 -0.27894 178360 0 0 0 0 0 0 178360 2261 1577 534 534 1017 1142;1143 9681 5912 Mix4_TiO2_Reinj_1_5 7757 9677 5910 Mix4_TiO2_Reinj_1_5 8353 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 1 117.874 1 101.16 5.17864E-33 177.34 1 117.874 2.09248E-33 188.01 1 77.3438 0.000587453 81.245 1 S FLEDNPSLKDIML CK2 0.117 2.09248E-33 188.01 _DLNFLEDNPpSLKDIM(ox)LANQPSPR_ DLNFLEDNPS(1)LKDIMLANQPSPR DLNFLEDNPS(117.87)LKDIMLANQPS(-117.87)PR 10 3 908.42973 0.75767 1918500 343010 0 0 1466400 0 109030 0 2262 1577 576 576 1908 2157 17533 10513 Mix4_InSol_TiO2_1 4081 17533 10513 Mix4_InSol_TiO2_1 4081 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.999967 44.7824 0 0 0 0 0.99878 29.1302 0.214027 29.13 0 0 0.999967 44.7824 0.00179167 93.523 0.998441 28.0655 0.226467 28.065 1 S REVHNRSPVSFRE Proline-directed 0.05 0.00179167 93.523 _EVHNRpSPVSFR_ EVHNRS(1)PVSFR EVHNRS(44.78)PVS(-44.78)FR 6 2 704.33008 0.098396 3456000 0 0 0 2978000 0 254780 223140 2263 1577 486 486 4909 5581;5582 47101 28796 Mix4_TiO2_Reinj_1_5 6631 47099 28795 Mix4_TiO2_Reinj_1_5 5899 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.372068 0 0 0 0.372068 0 3.60708E-06 102.08 1 S QRRHTLSEVTNQL 3.60708E-06 102.08 _RHpTLSEVTNQLVVMPGAGK_ RHT(0.372)LS(0.372)EVT(0.256)NQLVVMPGAGK RHT(0)LS(0)EVT(-1.63)NQLVVMPGAGK 5 3 706.35728 -0.27554 0 0 0 0 0 0 0 0 2264 1577 342 342 5705 6500 55959 34246 Mix4_TiO2_1_5 3228 55959 34246 Mix4_TiO2_1_5 3228 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.915839 10.3671 0.915839 10.3671 0.00357853 92.771 0.906939 9.88811 0.0165535 66.665 0 0 0 0 1 S RLKSHRSSFPVEQ CK1 0.081 0.00357853 92.771 _pSSFPVEQR_ S(0.916)S(0.084)FPVEQR S(10.37)S(-10.37)FPVEQR 1 2 515.22369 0.25217 951020 181160 0 0 769860 0 0 0 2265 1577 343 343 5705 6500 55960 34247 Mix4_TiO2_Reinj_1_1 3548 55959 34246 Mix4_TiO2_1_5 3228 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.899226 9.50521 0.620745 2.13982 0.00357853 92.771 0.899226 9.50521 0.0165535 66.665 0 0 0 0 1 S LKSHRSSFPVEQR AURORA;CK1;PKA 0.038874 0.00357853 92.771 _SpSFPVEQR_ S(0.101)S(0.899)FPVEQR S(-9.51)S(9.51)FPVEQR 2 2 515.22369 0.11783 111590 43612 0 0 67980 0 0 0 2266 1579 312 312 1707 1918 15582 9418 Mix4_TiO2_Reinj_1_5 2320 15582 9418 Mix4_TiO2_Reinj_1_5 2320 Q9H0X9 Q9H0X9 Q9H0X9 >sp|Q9H0X9|OSBL5_HUMAN Oxysterol-binding protein-related protein 5 OS=Homo sapiens GN=OSBPL5 PE=1 SV=1 0.997727 27.0978 0 0 0.997727 27.0978 0.106447 45.562 1 S RENPEESDTETQD CK2 0.117 0.106447 45.562 _ENPEEpSDTETQDHSR_ ENPEES(0.998)DT(0.002)ETQDHSR ENPEES(27.1)DT(-27.1)ET(-35.23)QDHS(-45.56)R 6 2 927.34471 0.11056 53315 0 0 0 53315 0 0 0 2267 1580 377 377 2026 2296 18539 11227 Mix4_TiO2_Reinj_1_5 3660 18539 11227 Mix4_TiO2_Reinj_1_5 3660 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.999333 31.7585 0 0 0 0 0.999333 31.7585 0.010195 61.94 1 S ISSHNQSPKRHSI CDK1;CDK2;CK1;Proline-directed 0.0057 0.010195 61.94 _FNISSHNQpSPK_ FNISS(0.001)HNQS(0.999)PK FNIS(-60.79)S(-31.76)HNQS(31.76)PK 9 2 669.79554 0.31056 196730 0 0 0 196730 0 0 0 2268 1580 1349 1349 2607 2967 24384 15134 Mix4_TiO2_Reinj_1_5 2996 24384 15134 Mix4_TiO2_Reinj_1_5 2996 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.9238 10.8951 0.9238 10.8951 0.0943548 39.162 1 S EKHKSPSYQIKEG 0.0943548 39.162 _HKSPpSYQIK_ HKS(0.075)PS(0.924)Y(0.001)QIK HKS(-10.9)PS(10.9)Y(-29.55)QIK 5 2 584.28154 0.16837 125550 0 0 0 125550 0 0 0 2269 1580 547 547 3543;3544 3996;3997 33436 20625 Mix4_TiO2_Reinj_1_1 8729 33436 20625 Mix4_TiO2_Reinj_1_1 8729 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 1 127.163 1.33732E-06 -55.7155 3.40842E-07 111.39 0 0 1 127.163 1.07584E-15 150.54 1 S LSKLLGSLDEVVL CK2;NEK6 0.076 1.07584E-15 150.54 _LLGpSLDEVVLLSPVPELR_ LLGS(1)LDEVVLLSPVPELR LLGS(127.16)LDEVVLLS(-127.16)PVPELR 4 2 1015.0527 0.23271 158700 0 0 0 158700 0 0 0 2270 1580 555 555 3543;3544 3996;3997 33435 20624 Mix4_TiO2_Reinj_1_1 8580 33436 20625 Mix4_TiO2_Reinj_1_1 8729 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 1 103.897 0.00271498 -22.6402 3.40842E-07 111.39 0 0 1 103.897 1.07584E-15 150.54 1 S DEVVLLSPVPELR Proline-directed 0.05 1.07584E-15 150.54 _LLGSLDEVVLLpSPVPELR_ LLGSLDEVVLLS(1)PVPELR LLGS(-103.9)LDEVVLLS(103.9)PVPELR 12 2 1015.0527 0.42054 178940 0 0 0 178940 0 0 0 2271 1580 563 563 3544 3997 33447 20630 Mix4_TiO2_Reinj_1_5 8878 33447 20630 Mix4_TiO2_Reinj_1_5 8878 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.5 0 0.498642 0 3.40842E-07 111.39 0 0 0.5 0 6.48207E-17 147.18 1 S VPELRDSSKLHDS NEK6;PKA 0.042 6.48207E-17 147.18 _LLGSLDEVVLLSPVPELRDpSSK_ LLGSLDEVVLLSPVPELRDS(0.5)S(0.5)K LLGS(-147.18)LDEVVLLS(-69.2)PVPELRDS(0)S(0)K 20 3 816.09953 0.41286 2630300 0 0 0 2630300 0 0 0 2272 1580 564 564 3544 3997 33443 20626 Mix4_TiO2_1_1 7680 33447 20630 Mix4_TiO2_Reinj_1_5 8878 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.86042 7.8996 0.86042 7.8996 3.40842E-07 111.39 0 0 0.5 0 6.48207E-17 147.18 1 S PELRDSSKLHDSL CAMK2 0.042 6.48207E-17 147.18 _LLGSLDEVVLLSPVPELRDSpSK_ LLGSLDEVVLLSPVPELRDS(0.14)S(0.86)K LLGS(-111.39)LDEVVLLS(-45.59)PVPELRDS(-7.9)S(7.9)K 21 3 816.09953 0.012392 2710200 79901 0 0 2630300 0 0 0 2273 1580 686 686 4013;4014 4570;4571 37945 23297 Mix4_InSol_TiO2_1 8005 37933 23293 Mix4_TiO2_Reinj_1_1 7249 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.88464 8.84711 0.0541542 -12.4219 2.83969E-22 203.69 0.0367791 -14.1812 8.56836E-12 162.54 0.00423289 -23.7152 6.66653E-30 215.67 0 0 0.88464 8.84711 3.94731E-24 214.37 0.0140687 -18.4559 5.73784E-16 176.87 1 S NFDFEGSLSPVIA PLK1 0.033462 6.66653E-30 215.67 _NFDFEGpSLSPVIAPKK_ NFDFEGS(0.885)LS(0.115)PVIAPKK NFDFEGS(8.85)LS(-8.85)PVIAPKK 7 2 914.94768 0.19449 56157 0 0 0 0 0 56157 0 2274 1580 688 688 4013;4014 4570;4571 37932 23292 Mix4_TiO2_2_2 6678 37933 23293 Mix4_TiO2_Reinj_1_1 7249 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.999786 36.6874 0.999001 29.9983 2.83969E-22 203.69 0.999786 36.6874 8.56836E-12 162.54 0.999187 30.8956 6.66653E-30 215.67 0 0 0.999653 34.5905 3.94731E-24 214.37 0.998999 29.9904 5.73784E-16 176.87 1 S DFEGSLSPVIAPK Proline-directed 0.05 6.66653E-30 215.67 _NFDFEGSLpSPVIAPK_ NFDFEGSLS(1)PVIAPK NFDFEGS(-36.69)LS(36.69)PVIAPK 9 2 850.9002 0.19785 7192300 1594800 106730 0 4276300 0 715760 498610 2275 1580 529 529 4445 5055 42258 26012 Mix4_TiO2_Reinj_2_1 3096 42255 26009 Mix4_TiO2_1_1 3219 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.833378 8.97902 0.102644 -9.244 0.0895003 33.81 0.0162353 -17.8158 0.219594 30.075 0 0 0.833378 8.97902 0.49174 14.351 1 S NTMPRPSTPLDGV PKA 0.042 0.0895003 33.81 _PpSTPLDGVSTPK_ PS(0.833)T(0.105)PLDGVS(0.031)T(0.031)PK PS(8.98)T(-8.98)PLDGVS(-14.35)T(-14.35)PK 2 2 639.8025 0.59314 22110 0 0 0 0 22110 0 0 2276 1580 50 50 4634 5260 43907 26926 Mix4_TiO2_1_5 8140 43908 26928 Mix4_TiO2_Reinj_1_1 8498 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.497834 0 0.497834 0 1.5899E-07 100.26 0 0 0.20299 -5.91714 2.76839E-18 138.88 0 0 1 S PASELWSSDGAAG CK1 0.143 2.76839E-18 138.88 _QLQPASELWpSSDGAAGLVGSLQEVTIHEK_ QLQPASELWS(0.498)S(0.498)DGAAGLVGS(0.004)LQEVTIHEK QLQPAS(-46.34)ELWS(0)S(0)DGAAGLVGS(-20.62)LQEVT(-50.73)IHEK 10 3 1044.1746 0.25058 0 0 0 0 0 0 0 0 2277 1580 51 51 4634 5260 43908 26928 Mix4_TiO2_Reinj_1_1 8498 43908 26928 Mix4_TiO2_Reinj_1_1 8498 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.79413 6.23337 0.497834 0 1.5899E-07 100.26 0 0 0.79413 6.23337 2.76839E-18 138.88 0 0 1 S ASELWSSDGAAGL NEK6 0.076 2.76839E-18 138.88 _QLQPASELWSpSDGAAGLVGSLQEVTIHEK_ QLQPAS(0.017)ELWS(0.189)S(0.794)DGAAGLVGSLQEVTIHEK QLQPAS(-16.74)ELWS(-6.23)S(6.23)DGAAGLVGS(-100.27)LQEVT(-120.19)IHEK 11 3 1044.1746 0.57333 3597700 0 0 0 3597700 0 0 0 2278 1581 547 547 6749 7723 68475 42033 Mix4_TiO2_1_3 3805 68476 42034 Mix4_TiO2_Reinj_1_5 4429 Q9H1C4 Q9H1C4 Q9H1C4 >sp|Q9H1C4|UN93B_HUMAN Protein unc-93 homolog B1 OS=Homo sapiens GN=UNC93B1 PE=1 SV=2 0.998905 29.5989 0.998905 29.5989 0.274997 55.43 0.984137 17.9118 0.0110354 74.793 2 S YLEEDNSDESDAE 0.0110354 74.793 _YLEEDNpSDEpSDAEGEHGDGAEEEAPPAGPR_ Y(0.001)LEEDNS(0.999)DES(1)DAEGEHGDGAEEEAPPAGPR Y(-29.6)LEEDNS(29.6)DES(36.2)DAEGEHGDGAEEEAPPAGPR 7 3 1111.4069 -0.065736 457760 100190 0 0 357570 0 0 0 2279 1581 550 550 6749 7723 68475 42033 Mix4_TiO2_1_3 3805 68476 42034 Mix4_TiO2_Reinj_1_5 4429 Q9H1C4 Q9H1C4 Q9H1C4 >sp|Q9H1C4|UN93B_HUMAN Protein unc-93 homolog B1 OS=Homo sapiens GN=UNC93B1 PE=1 SV=2 0.999761 36.2009 0.999761 36.2009 0.274997 55.43 0.99661 24.6142 0.0110354 74.793 2 S EDNSDESDAEGEH CK1;CK2 0.081 0.0110354 74.793 _YLEEDNpSDEpSDAEGEHGDGAEEEAPPAGPR_ Y(0.001)LEEDNS(0.999)DES(1)DAEGEHGDGAEEEAPPAGPR Y(-29.6)LEEDNS(29.6)DES(36.2)DAEGEHGDGAEEEAPPAGPR 10 3 1111.4069 -0.065736 457760 100190 0 0 357570 0 0 0 2280 1582 181 181 595;596;3492 684;685;3943;3944 5674 3362 Mix4_InSol_Tio2_Reinj_1 2915 32974 20423 Mix4_InSol_Tio2_Reinj_1 3627 Q9H1E3;Q9H1E3-2 Q9H1E3 Q9H1E3 >sp|Q9H1E3|NUCKS_HUMAN Nuclear ubiquitous casein and cyclin-dependent kinases substrate OS=Homo sapiens GN=NUCKS1 PE=1 SV=1;>sp|Q9H1E3-2|NUCKS_HUMAN Isoform 2 of Nuclear ubiquitous casein and cyclin-dependent kinases substrate OS=Homo sapiens GN=NUCKS1 0.999957 46.6965 0.987551 19.0472 0.108447 38.166 0.777052 8.43277 0.734355 8.4328 0.999948 42.8735 0.00334986 72.795 0.99983 37.6923 0.00190655 92.742 0.999957 46.6965 4.04427E-05 122.61 1 S KATVTPSPVKGKG CDK1;CDK2;CK1;Proline-directed 0.0057 4.04427E-05 122.61 _ATVTPpSPVKGK_ ATVTPS(1)PVKGK AT(-46.7)VT(-46.7)PS(46.7)PVKGK 6 2 582.80485 -0.3527 1859800 66090 21803 0 405810 0 758350 607730 2281 1582 214 214 6156 7028 60961 36933 Mix4_TiO2_1_4 2379 60961 36933 Mix4_TiO2_1_4 2379 Q9H1E3;Q9H1E3-2 Q9H1E3 Q9H1E3 >sp|Q9H1E3|NUCKS_HUMAN Nuclear ubiquitous casein and cyclin-dependent kinases substrate OS=Homo sapiens GN=NUCKS1 PE=1 SV=1;>sp|Q9H1E3-2|NUCKS_HUMAN Isoform 2 of Nuclear ubiquitous casein and cyclin-dependent kinases substrate OS=Homo sapiens GN=NUCKS1 1 69.729 1 69.729 0.0127133 69.729 0.99495 25.9555 0.668879 25.955 0 0 0.993767 25.0361 0.699781 25.036 1 S EDEEPESPPEKKT CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.000145 0.0127133 69.729 _TPSPKEEDEEPEpSPPEKK_ TPSPKEEDEEPES(1)PPEKK T(-69.73)PS(-69.73)PKEEDEEPES(69.73)PPEKK 13 3 711.64722 -0.88326 333730 46081 0 0 189820 0 0 97828 2282 1583 4 4 3829 4328 36345 22439 Mix4_TiO2_Reinj_1_2 4490 36345 22439 Mix4_TiO2_Reinj_1_2 4490 Q9H1U9 Q9H1U9 Q9H1U9 >sp|Q9H1U9|MCAR1_HUMAN Mitochondrial carrier triple repeat protein 1 OS=Homo sapiens GN=MCART1 PE=2 SV=1 0.999981 47.2855 0.907475 9.91576 1.16109 9.9158 0.999981 47.2855 0.113716 47.286 2 S ___MMDSEAHEKR 0.113716 47.286 _MDpSEAHEKRPPILpTSSK_ MDS(1)EAHEKRPPILT(0.333)S(0.333)S(0.333)K MDS(47.29)EAHEKRPPILT(0)S(0)S(0)K 3 2 1043.4574 -1.0595 266300 0 8912.8 0 257390 0 0 0 2283 1583 16 16 3829 4328 36346 22440 Mix4_TiO2_Reinj_1_6 4422 36345 22439 Mix4_TiO2_Reinj_1_2 4490 Q9H1U9 Q9H1U9 Q9H1U9 >sp|Q9H1U9|MCAR1_HUMAN Mitochondrial carrier triple repeat protein 1 OS=Homo sapiens GN=MCART1 PE=2 SV=1 0.399737 0 0.364175 0 1.16109 9.9158 0.399737 0 0.113716 47.286 2 S RPPILTSSKQDIS 0.113716 47.286 _MDpSEAHEKRPPILpTSSK_ MDS(0.801)EAHEKRPPILT(0.4)S(0.4)S(0.4)K MDS(6.04)EAHEKRPPILT(0)S(0)S(0)K 15 2 1043.4574 -0.39963 0 0 0 0 0 0 0 0 2284 1583 17 17 3829 4328 36346 22440 Mix4_TiO2_Reinj_1_6 4422 36345 22439 Mix4_TiO2_Reinj_1_2 4490 Q9H1U9 Q9H1U9 Q9H1U9 >sp|Q9H1U9|MCAR1_HUMAN Mitochondrial carrier triple repeat protein 1 OS=Homo sapiens GN=MCART1 PE=2 SV=1 0.399737 0 0.364175 0 1.16109 9.9158 0.399737 0 0.113716 47.286 2 S PPILTSSKQDISP CK2;NEK6 0.076 0.113716 47.286 _MDpSEAHEKRPPILpTSSK_ MDS(0.801)EAHEKRPPILT(0.4)S(0.4)S(0.4)K MDS(6.04)EAHEKRPPILT(0)S(0)S(0)K 16 2 1043.4574 -0.39963 0 0 0 0 0 0 0 0 2285 1584 79 79 645 742 6195 3626 Mix4_TiO2_Reinj_1_4 4111 6195 3626 Mix4_TiO2_Reinj_1_4 4111 Q9H1Z4 Q9H1Z4 Q9H1Z4 >sp|Q9H1Z4|WDR13_HUMAN WD repeat-containing protein 13 OS=Homo sapiens GN=WDR13 PE=1 SV=2 0.819969 6.58457 0.819969 6.58457 0.0209554 61.306 1 S GSARAYSNSIVRS CAMK2 0.042 0.0209554 61.306 _AYpSNSIVR_ AYS(0.82)NS(0.18)IVR AY(-54.79)S(6.58)NS(-6.58)IVR 3 2 495.22623 0.48815 104160 0 0 0 104160 0 0 0 2286 1586 340 340 526;4818 595;597;5468 46000 28143 Mix4_TiO2_Reinj_1_1 7028 4916 2971 Mix4_TiO2_Reinj_1_5 7762 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.95721 14.3237 0.745407 5.18812 3.0224E-12 128.05 0 0 0.95721 14.3237 9.24032E-19 152.99 0 0 0 0 0 0 1 S PASKRASSDLSIA CK1;GSK3;PKA 0.042 9.24032E-19 152.99 _RApSSDLSIASSEEDKLSQNACILESVSEK_ RAS(0.957)S(0.035)DLS(0.007)IASSEEDKLSQNACILESVSEK RAS(14.32)S(-14.32)DLS(-21.17)IAS(-42.81)S(-42.81)EEDKLS(-75.41)QNACILES(-93.95)VS(-93.95)EK 3 3 1078.5008 0.039741 1056500 1.0191 205680 0 0 850830 0 0 0 2287 1586 347 347 526;4818 595;597;5468 4916 2971 Mix4_TiO2_Reinj_1_5 7762 4916 2971 Mix4_TiO2_Reinj_1_5 7762 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.87645 8.52046 0.859289 8.23207 3.0224E-12 128.05 0 0 0.87645 8.52046 9.24032E-19 152.99 0 0 0 0 0 0 1 S SDLSIASSEEDKL CK1;CK2 0.081 9.24032E-19 152.99 _ASSDLSIApSSEEDKLSQNACILESVSEK_ ASSDLSIAS(0.876)S(0.123)EEDKLSQNACILESVSEK AS(-63.87)S(-63.87)DLS(-44.29)IAS(8.52)S(-8.52)EEDKLS(-34.7)QNACILES(-123.63)VS(-135.28)EK 9 3 1026.4671 -0.17106 740410 0.71419 134970 0 0 605440 0 0 0 2288 1586 348 348 526;4818 595;597;5468 4923 2974 Mix4_TiO2_Reinj_1_5 7938 4923 2974 Mix4_TiO2_Reinj_1_5 7938 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.999896 40.3064 0.129102 -8.23207 3.0224E-12 128.05 0 0 0.999896 40.3064 8.40672E-13 134.79 0 0 0 0 0 0 2 S DLSIASSEEDKLS CK1;CK2 0.117 8.40672E-13 134.79 _ASSDLSIApSpSEEDKLSQNACILESVSEK_ ASSDLSIAS(1)S(1)EEDKLSQNACILESVSEK AS(-56.97)S(-56.97)DLS(-40.31)IAS(40.31)S(40.31)EEDKLS(-53.92)QNACILES(-121.56)VS(-128.76)EK 10 3 1053.1226 0.54908 449290 0.43338 0 0 0 449290 0 0 0 2289 1586 777 777 1211;6039 1363;6888 11382 6972 Mix4_TiO2_1_1 3093 59671 36207 Mix4_InSol_Tio2_Reinj_1 4119 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.941237 12.0466 0.941237 12.0466 4.45482E-05 120.87 0 0 0.141748 -6.81938 1.91081E-05 131.63 0.207214 -5.74624 3.98226E-05 122.87 8.10984E-05 -40.9046 5.40332E-06 137.87 1 S LSKTKDSGSISLQ F box bTrCP;GSK3 0.000624338 5.40332E-06 137.87 _DpSGSISLQETR_ DS(0.941)GS(0.059)ISLQETR DS(12.05)GS(-12.05)IS(-50.74)LQET(-75.55)R 2 2 636.77701 0.076836 119870 1.209 119870 0 0 0 0 0 0 2290 1586 779 779 1211;6039 1363;6888 59671 36207 Mix4_InSol_Tio2_Reinj_1 4119 59671 36207 Mix4_InSol_Tio2_Reinj_1 4119 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.998782 29.439 0.997158 26.189 4.45482E-05 120.87 0 0 0.998363 27.8594 1.91081E-05 131.63 0.994666 22.9894 3.98226E-05 122.87 0.998782 29.439 5.40332E-06 137.87 1 S KTKDSGSISLQET 5.40332E-06 137.87 _TKDSGpSISLQETR_ TKDSGS(0.999)IS(0.001)LQETR T(-88.77)KDS(-40.9)GS(29.44)IS(-29.44)LQET(-91.52)R 6 2 751.34833 0.27058 1581200 15.947 156930 0 0 942240 0 289380 192610 2291 1586 565 565 1309;1310;6356;6357 1476;1479;7269;7271;7272 64137 39343 Mix4_TiO2_1_5 1516 64178 39377 Mix4_TiO2_Reinj_1_1 3637 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.999984 48.0436 0.999984 48.0436 3.5812E-17 141.26 0.000343744 -32.7344 3.19507E-11 120.47 0.906374 9.96056 1.07988E-17 152.03 0.000120849 -39.0882 0.0133962 65.648 0 0 0 0 1 S QKVDEDSAEDTQS CK2 0.117 1.07988E-17 152.03 _VDEDpSAEDTQSNDGK_ VDEDS(1)AEDTQSNDGK VDEDS(48.04)AEDT(-48.04)QS(-82.38)NDGK 5 2 845.3098 0.060909 853100 0.017477 199710 0 0 653390 0 0 0 2292 1586 571 571 1309;1310;6356;6357 1476;1479;7269;7271;7272 64178 39377 Mix4_TiO2_Reinj_1_1 3637 64178 39377 Mix4_TiO2_Reinj_1_1 3637 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.986562 18.6585 0.795328 5.23152 0.120901 52.064 0.848094 7.47698 3.19507E-11 120.47 0.986562 18.6585 1.07988E-17 152.03 0.979625 16.8454 0.0133962 65.648 0 0 0 0 1 S SAEDTQSNDGKEV 1.07988E-17 152.03 _VDEDSAEDTQpSNDGKEVVEVGQK_ VDEDSAEDT(0.013)QS(0.987)NDGKEVVEVGQK VDEDS(-57.62)AEDT(-18.66)QS(18.66)NDGKEVVEVGQK 11 2 1279.5425 -0.020087 1779600 0.036458 1102800 42688 0 610590 23518 0 0 2293 1586 816 816 2943 3349 28073 17448 Mix4_TiO2_Reinj_1_1 3203 28072 17447 Mix4_TiO2_1_5 3174 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.970849 15.3363 4.59675E-06 -51.1555 0.00739498 76.353 0 0 0.970849 15.3363 0.013113 69.561 0 0 1 S SKIVTDSDSKTEE 0.00739498 76.353 _IVTDpSDSKTEELR_ IVT(0.001)DS(0.971)DS(0.028)KTEELR IVT(-32.4)DS(15.34)DS(-15.34)KT(-37.33)EELR 5 2 786.86127 0.23284 47959 0.29914 0 0 0 47959 0 0 0 2294 1586 189 189 4838 5496;5497;5498 46225 28256 Mix4_TiO2_Reinj_1_5 7451 46222 28252 Mix4_TiO2_Reinj_1_1 7013 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.999641 34.5245 0.989747 19.8469 5.82647E-24 162.75 0.958466 13.6518 1.36234E-05 98.42 0.999641 34.5245 7.69469E-25 174.21 0 0 0 0 1 S TIQRRDSFIGTPY AURORA;AURORA-A;CAMK2;CHK1;PKA;PKD 0.004788 7.69469E-25 174.21 _RDpSFIGTPYWM(ox)APEVVM(ox)CETSK_ RDS(1)FIGTPYWMAPEVVMCETSK RDS(34.52)FIGT(-34.52)PY(-52.17)WMAPEVVMCET(-123.8)S(-123.8)K 3 3 906.05461 -0.16589 7501200 1381800 41900 0 6077500 0 0 0 2295 1586 370 370 5520;5970 6284;6808 58954 35764 Mix4_InSol_Tio2_Reinj_1 2116 53873 32955 Mix4_TiO2_Reinj_1_5 1897 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.290686 0.897061 0.0533125 -12.4938 0.0011273 86.515 0 0 0.0287167 -15.2911 0.0011273 86.515 0 0 0.153665 -7.3834 0.000918148 82.554 0.290686 0.897061 0.988146 0.89706 1 S SEKTERSNSEDKL CK2 0.117 0.0011273 86.515 _TERpSNSEDKLNSK_ T(0.236)ERS(0.291)NS(0.236)EDKLNS(0.236)K T(-0.9)ERS(0.9)NS(-0.9)EDKLNS(-0.9)K 4 2 794.35415 0.55543 0 0 0 0 0 0 0 0 0 2296 1586 372 372 5520;5970 6284;6808 53873 32955 Mix4_TiO2_Reinj_1_5 1897 53873 32955 Mix4_TiO2_Reinj_1_5 1897 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.999154 30.7241 0.998014 27.0118 0.0011273 86.515 0 0 0.999154 30.7241 0.0011273 86.515 0 0 0.983734 17.816 0.000918148 82.554 0.236438 -0.897061 0.988146 0.89706 1 S KTERSNSEDKLNS CAMK2 0.042 0.0011273 86.515 _SNpSEDKLNSK_ S(0.001)NS(0.999)EDKLNSK S(-30.72)NS(30.72)EDKLNS(-79.37)K 3 2 601.25846 -0.51067 2902600 16.093 278650 0 0 1899300 0 724680 0 2297 1587 52 52 5479 6235 53431 32639 Mix4_TiO2_Reinj_1_5 3203 53431 32639 Mix4_TiO2_Reinj_1_5 3203 Q9H2H9 Q9H2H9 Q9H2H9 >sp|Q9H2H9|S38A1_HUMAN Sodium-coupled neutral amino acid transporter 1 OS=Homo sapiens GN=SLC38A1 PE=1 SV=1 0.99986 41.5609 0.981062 20.154 0.384785 20.154 0 0 0.99986 41.5609 0.0673467 41.561 0 0 0 0 1 S DRESRRSLTNSHL AURORA;AURORA-1;CK1;GSK3;PKA 0.020748 0.0673467 41.561 _pSLTNSHLEK_ S(1)LTNSHLEK S(41.56)LT(-41.56)NS(-41.56)HLEK 1 2 554.75535 3.1593 627020 128950 0 0 498070 0 0 0 2298 1588 324 324 4049 4615 38312 23505 Mix4_InSol_TiO2_1 4492 38312 23505 Mix4_InSol_TiO2_1 4492 Q9H2K8 Q9H2K8 Q9H2K8 >sp|Q9H2K8|TAOK3_HUMAN Serine/threonine-protein kinase TAO3 OS=Homo sapiens GN=TAOK3 PE=1 SV=2 1 64.5415 1 64.5415 0.00024478 91 0 0 1 S NGPLNESQEDEED CK2;NEK6 0.076 0.00024478 91 _NGPLNEpSQEDEEDSEHGTSLNR_ NGPLNES(1)QEDEEDSEHGTSLNR NGPLNES(64.54)QEDEEDS(-64.54)EHGT(-83.89)S(-83.37)LNR 7 3 846.34018 0.36491 130230 0.024347 0 0 0 0 0 130230 0 2299 1588 442 442 5120 5824 49546 30271 Mix4_TiO2_1_5 2268 49548 30273 Mix4_TiO2_Reinj_1_5 3060 Q9H2K8 Q9H2K8 Q9H2K8 >sp|Q9H2K8|TAOK3_HUMAN Serine/threonine-protein kinase TAO3 OS=Homo sapiens GN=TAOK3 PE=1 SV=2 0.999434 32.7026 0.999434 32.7026 0.154471 45.268 0.999225 31.2176 0.144682 46.986 1 S ATIKSASLVTRQI 0.144682 46.986 _SApSLVTR_ S(0.001)AS(0.999)LVTR S(-32.7)AS(32.7)LVT(-45.27)R 3 2 407.19694 0.035744 621670 83490 0 0 538180 0 0 0 2300 1589 875 875 2067 2342 18947 11556 Mix4_TiO2_Reinj_1_6 7660 18947 11556 Mix4_TiO2_Reinj_1_6 7660 Q9H2M9 Q9H2M9 Q9H2M9 >sp|Q9H2M9|RBGPR_HUMAN Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens GN=RAB3GAP2 PE=1 SV=1 0.951352 13.6573 0.951352 13.6573 9.33784E-19 152.97 0.325987 -0.802427 0.000259631 81.518 1 S SEALTDSWEALSL NEK6 0.076 9.33784E-19 152.97 _FSQTVLGADSEALTDpSWEALSLDTEYWK_ FSQTVLGADS(0.008)EALT(0.041)DS(0.951)WEALSLDTEYWK FS(-78.76)QT(-85.22)VLGADS(-20.94)EALT(-13.66)DS(13.66)WEALS(-57.48)LDT(-68.99)EY(-96.34)WK 16 3 1081.4866 0.66325 111010 0 0 0 111010 0 0 0 2301 1592 827 827 4381 4983 41569 25555 Mix4_TiO2_1_5 3369 41569 25555 Mix4_TiO2_1_5 3369 Q9H2X6;Q9H2X6-3 Q9H2X6 Q9H2X6 >sp|Q9H2X6|HIPK2_HUMAN Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2 PE=1 SV=2;>sp|Q9H2X6-3|HIPK2_HUMAN Isoform 3 of Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2 0.999965 44.525 0.999965 44.525 1.3332E-21 173.07 0 0 0.818046 6.61442 0.513404 30.581 0.998892 29.5494 6.10713E-07 116.4 1 S SSQAISSPQRSKR CDK1;CDK2;GSK3;Polo box;Proline-directed 0.00405 1.3332E-21 173.07 _NVSTCEVSSSQAISpSPQR_ NVSTCEVSSSQAISS(1)PQR NVS(-170.13)T(-170.66)CEVS(-138.04)S(-125.58)S(-118.7)QAIS(-44.53)S(44.53)PQR 15 2 1008.9383 0.021608 300570 181980 0 0 0 0 7538.6 111060 2302 1592 121 121 5810 6626 57284 34904 Mix4_TiO2_Reinj_1_5 6334 57284 34904 Mix4_TiO2_Reinj_1_5 6334 Q9H2X6;Q9H2X6-3;Q9H2X6-2 Q9H2X6 Q9H2X6 >sp|Q9H2X6|HIPK2_HUMAN Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2 PE=1 SV=2;>sp|Q9H2X6-3|HIPK2_HUMAN Isoform 3 of Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2;>sp|Q9H2X6-2|HIPK2_HUMAN Isoform 2 of Homeodomain-int 0.968385 17.2106 0 0 0.968385 17.2106 0.0262343 55.684 1 S MRRSTVSLLDTYQ CK1;CK2 0.081 0.0262343 55.684 _STVpSLLDTYQK_ S(0.013)T(0.018)VS(0.968)LLDTYQK S(-18.76)T(-17.21)VS(17.21)LLDT(-34.66)Y(-55.68)QK 4 2 667.81561 0.2674 158990 0 0 0 158990 0 0 0 2303 1593 332 332 2176 2464 20013 12326 Mix4_TiO2_Reinj_1_1 4683 20015 12328 Mix4_TiO2_Reinj_1_5 5223 Q9H330;Q9H330-2;Q9H330-4 Q9H330 Q9H330 >sp|Q9H330|CI005_HUMAN Transmembrane protein C9orf5 OS=Homo sapiens GN=C9orf5 PE=1 SV=2;>sp|Q9H330-2|CI005_HUMAN Isoform 2 of Transmembrane protein C9orf5 OS=Homo sapiens GN=C9orf5;>sp|Q9H330-4|CI005_HUMAN Isoform 4 of Transmembrane protein C9orf5 OS=Homo 0.498355 0 0.436154 -0.965928 1.73838E-12 133.36 0 0 0.498355 0 2.81288E-18 148.62 0 0 0 0 1 S PSPTSPSPTLGRR Proline-directed 0.05 2.81288E-18 148.62 _GESAPTLSTSPSPSSPSPTSPpSPTLGR_ GESAPTLSTSPSPSSPSPT(0.001)S(0.003)PS(0.498)PT(0.498)LGR GES(-116.71)APT(-111.08)LS(-112.16)T(-106.93)S(-107.49)PS(-96.63)PS(-57.36)S(-64.6)PS(-50.82)PT(-29.59)S(-22.6)PS(0)PT(0)LGR 22 2 1331.6158 0.77102 0 0 0 0 0 0 0 0 2304 1595 247 247 3253;6380 3687;7300 64456 39561 Mix4_TiO2_Reinj_1_2 3313 64455 39560 Mix4_TiO2_Reinj_1_2 3282 Q9H3N1 Q9H3N1 Q9H3N1 >sp|Q9H3N1|TMX1_HUMAN Thioredoxin-related transmembrane protein 1 OS=Homo sapiens GN=TMX1 PE=1 SV=1 1 81.261 1 69.138 5.93575E-32 196.24 1 81.261 7.08532E-33 212.34 0 0 0 0 1 S ADEEDVSEEEAES CK2 0.117 7.08532E-33 212.34 _VEEEQEADEEDVpSEEEAESK_ VEEEQEADEEDVS(1)EEEAESK VEEEQEADEEDVS(81.26)EEEAES(-81.26)K 13 3 797.3024 0.14497 6469500 107.8 1235100 0 0 5234400 0 0 0 2305 1597 10 10 5476 6232 53406 32628 Mix4_TiO2_Reinj_1_6 7180 53406 32628 Mix4_TiO2_Reinj_1_6 7180 Q9H3Z4;Q9H3Z4-2 Q9H3Z4 Q9H3Z4 >sp|Q9H3Z4|DNJC5_HUMAN DnaJ homolog subfamily C member 5 OS=Homo sapiens GN=DNAJC5 PE=1 SV=1;>sp|Q9H3Z4-2|DNJC5_HUMAN Isoform 2 of DnaJ homolog subfamily C member 5 OS=Homo sapiens GN=DNAJC5 0.89324 10.0809 0.23418 -0.804616 0.20364 39.471 0.89324 10.0809 0.0143433 68.984 1 S QRQRSLSTSGESL CAMK2;PKA/AKT 0.00111111 0.0143433 68.984 _SLpSTSGESLYHVLGLDK_ S(0.088)LS(0.893)T(0.018)S(0.001)GESLYHVLGLDK S(-10.08)LS(10.08)T(-16.9)S(-30.31)GES(-55.75)LY(-68.98)HVLGLDK 3 2 943.45079 0.20805 134820 0 0 0 134820 0 0 0 2306 1597 12 12 5476 6232 53405 32627 Mix4_TiO2_1_6 6339 53406 32628 Mix4_TiO2_Reinj_1_6 7180 Q9H3Z4;Q9H3Z4-2 Q9H3Z4 Q9H3Z4 >sp|Q9H3Z4|DNJC5_HUMAN DnaJ homolog subfamily C member 5 OS=Homo sapiens GN=DNAJC5 PE=1 SV=1;>sp|Q9H3Z4-2|DNJC5_HUMAN Isoform 2 of DnaJ homolog subfamily C member 5 OS=Homo sapiens GN=DNAJC5 0.281846 0 0.281846 0 0.20364 39.471 0.00342797 -23.9623 0.0143433 68.984 1 S QRSLSTSGESLYH CK1;NEK6 0.076 0.0143433 68.984 _SLSpTSGESLYHVLGLDK_ S(0.195)LS(0.234)T(0.282)S(0.282)GES(0.007)LYHVLGLDK S(-1.6)LS(-0.8)T(0)S(0)GES(-16.09)LY(-39.47)HVLGLDK 5 2 943.45079 0.040289 0 0 0 0 0 0 0 0 2307 1598 3 3 494 560 4558 2758 Mix4_InSol_Tio2_Reinj_2 1315 4559 2761 Mix4_TiO2_1_3 1383 Q9H4A4 Q9H4A4 Q9H4A4 >sp|Q9H4A4|AMPB_HUMAN Aminopeptidase B OS=Homo sapiens GN=RNPEP PE=1 SV=2 0.545726 0.892694 3.49843E-08 -74.5604 0.000589636 99.583 0 0 0.0020788 -26.782 0.0030928 87.188 0.0658835 -11.1986 0.204629 33.927 0.545726 0.892694 0.0623641 48.986 1 S ____MASGEHSPG GSK3 0.081 0.000589636 99.583 _(ac)ApSGEHSPGSGAAR_ AS(0.546)GEHS(0.444)PGS(0.01)GAAR AS(0.89)GEHS(-0.89)PGS(-17.39)GAAR 2 2 653.26461 -0.51417 54551 0 0 0 0 0 0 54551 2308 1598 7 7 494 560 4560 2763 Mix4_TiO2_Reinj_1_3 1841 4559 2761 Mix4_TiO2_1_3 1383 Q9H4A4 Q9H4A4 Q9H4A4 >sp|Q9H4A4|AMPB_HUMAN Aminopeptidase B OS=Homo sapiens GN=RNPEP PE=1 SV=2 0.999849 38.2034 0.999801 37.0039 0.000589636 99.583 0 0 0.999849 38.2034 0.0030928 87.188 0.997908 29.2133 0.204629 33.927 0.999621 34.9752 0.0623641 48.986 1 S MASGEHSPGSGAA CK1;Proline-directed 0.05 0.000589636 99.583 _(ac)ASGEHpSPGSGAAR_ ASGEHS(1)PGSGAAR AS(-68.04)GEHS(38.2)PGS(-38.2)GAAR 6 2 653.26461 -0.56687 6588800 957340 0 0 3987200 0 752630 891620 2309 1599 94 94 1823 2058 16713 10057 Mix4_TiO2_1_4 4666 16712 10056 Mix4_TiO2_1_4 4650 Q9H4B6 Q9H4B6 Q9H4B6 >sp|Q9H4B6|SAV1_HUMAN Protein salvador homolog 1 OS=Homo sapiens GN=SAV1 PE=1 SV=2 0.999997 55.7243 0.999997 55.7243 7.04093E-09 161.03 0 0 0.997896 26.7616 0.0165417 65.488 0.77711 10.1951 0.736997 10.195 0.980569 21.8011 0.0419416 54.535 1 S RESNRLSAPSYLA CK1;PKA 0.042 7.04093E-09 161.03 _ESNRLpSAPSYLAR_ ESNRLS(1)APSYLAR ES(-55.72)NRLS(55.72)APS(-61.74)Y(-68.55)LAR 6 3 515.247 0.094324 6228700 1314500 0 0 3869600 0 323100 721480 2310 1599 27 27 3015;6821 3429;7805 28788 17925 Mix4_TiO2_Reinj_1_4 3710 28788 17925 Mix4_TiO2_Reinj_1_4 3710 Q9H4B6 Q9H4B6 Q9H4B6 >sp|Q9H4B6|SAV1_HUMAN Protein salvador homolog 1 OS=Homo sapiens GN=SAV1 PE=1 SV=2 0.999967 44.7662 0.999431 32.4467 0.0473063 56.318 0 0 0.999967 44.7662 0.00399662 90.481 0.492619 0 0.438646 15.233 0 0 1 S YVKKETSPLLRNL CHK1;PKD;Proline-directed 0.020748 0.00399662 90.481 _KETpSPLLR_ KETS(1)PLLR KET(-44.77)S(44.77)PLLR 4 2 512.26536 0.23718 769790 113050 0 0 656740 0 0 0 2311 1599 136 136 6827 7812 69192 42404 Mix4_TiO2_Reinj_1_4 7165 69191 42403 Mix4_TiO2_1_4 6416 Q9H4B6 Q9H4B6 Q9H4B6 >sp|Q9H4B6|SAV1_HUMAN Protein salvador homolog 1 OS=Homo sapiens GN=SAV1 PE=1 SV=2 0.999999 59.2522 0.999988 49.0642 7.76918E-05 126.5 0.999999 59.2522 0.000599435 109.17 1 S GSRYYYSDNFFDG 7.76918E-05 126.5 _YYYpSDNFFDGQR_ YYYS(1)DNFFDGQR Y(-94.62)Y(-94.62)Y(-59.25)S(59.25)DNFFDGQR 4 2 827.81413 0.6031 477240 136270 0 0 340980 0 0 0 2312 1600 169 169 4064 4631 38538 23646 Mix4_TiO2_1_3 3879 38539 23647 Mix4_TiO2_Reinj_1_3 4478 Q9H4L4 Q9H4L4 Q9H4L4 >sp|Q9H4L4|SENP3_HUMAN Sentrin-specific protease 3 OS=Homo sapiens GN=SENP3 PE=1 SV=2 0.99696 25.1578 0.99696 25.1578 0.00129193 78.871 0.954047 13.1725 3.5858E-16 147.84 0 0 0.995403 23.3632 0.100621 50.969 1 S HPKNHLSPQQGGA Proline-directed 0.05 3.5858E-16 147.84 _NHLpSPQQGGATPQVPSPCCR_ NHLS(0.997)PQQGGAT(0.003)PQVPSPCCR NHLS(25.16)PQQGGAT(-25.16)PQVPS(-78.87)PCCR 4 3 757.66467 -0.010587 687900 154110 0 0 376420 0 0 157370 2313 1601;1602 410;379 410 2780;4914 3169;5587 47125 28806 Mix4_TiO2_Reinj_1_5 6144 26608 16619 Mix4_TiO2_Reinj_1_5 6426 Q9H4L5;Q9H4L5-5;Q9H4L5-2;Q9H4L5-6 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-2|OSBL3_HUMAN Isoform 1b of Oxyst 1 116.73 0.99995 42.987 0.120756 42.987 0 0 1 116.73 4.41994E-16 181.06 0.972931 15.5561 0.81967 15.556 0.663937 2.95705 1.2556 2.9571 1 S ESLLLDSPAVAKS NEK6;Proline-directed 0.05 4.41994E-16 181.06 _RIHAESLLLDpSPAVAK_ RIHAESLLLDS(1)PAVAK RIHAES(-116.73)LLLDS(116.73)PAVAK 11 3 600.65203 -0.43267 1167600 45854 0 0 1064200 0 27882 29691 2314 1601;1602 186;186 186 3206 3636 30429 18919 Mix4_InSol_Tio2_Reinj_1 1190 30428 18918 Mix4_InSol_TiO2_1 1129 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.668978 3.05821 0.651842 2.84468 0.0694323 67.943 0.668978 3.05821 0.0973974 55.284 1 S SSRKRSSISKQNL AURORA;AURORA-1;AURORA-A;PKA 0.006142092 0.0694323 67.943 _KRSpSISK_ KRS(0.331)S(0.669)ISK KRS(-3.06)S(3.06)IS(-35.19)K 4 2 443.23132 0.15312 382170 0 0 0 0 0 169650 212510 2315 1601;1602 303;272 303 3476 3923 32746 20288 Mix4_TiO2_1_3 5635 32747 20290 Mix4_TiO2_1_3 5583 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.5 0 0.5 0 3.30858E-20 180.03 0.38194 0 0.0110156 71.812 0.499996 0 1.93619E-09 132.12 0 0 0.497055 0 6.26167E-06 106.25 0.00435507 -23.5911 0.000191639 97.087 1 S GPVRLHSSNPNLS CAMK2 0.042 3.30858E-20 180.03 _LHpSSNPNLSTLDFGEEK_ LHS(0.5)S(0.5)NPNLSTLDFGEEK LHS(0)S(0)NPNLS(-58.68)T(-65.43)LDFGEEK 3 3 656.62973 0.1391 4916900 1243400 0 0 3673600 0 0 0 2316 1601;1602 304;273 304 3476 3923 32747 20290 Mix4_TiO2_1_3 5583 32747 20290 Mix4_TiO2_1_3 5583 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.997464 26.0376 0.997464 26.0376 3.30858E-20 180.03 0.966188 14.56 0.0110156 71.812 0.996614 24.7754 1.93619E-09 132.12 0 0 0.966896 14.655 6.26167E-06 106.25 0.995645 23.5911 0.000191639 97.087 1 S PVRLHSSNPNLST NEK6 0.076 3.30858E-20 180.03 _LHSpSNPNLSTLDFGEEK_ LHS(0.002)S(0.997)NPNLSTLDFGEEK LHS(-26.04)S(26.04)NPNLS(-42.95)T(-58.59)LDFGEEK 4 2 984.44095 0.15895 9381000 2482300 32905 0 6743900 0 69016 52822 2317 1601;1602 371;340 371 3509;4627 3962;5250;5251 33114 20473 Mix4_InSol_Tio2_Reinj_1 6699 43867 26888 Mix4_TiO2_1_5 4910 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.59522 1.91991 0.0928487 -9.27647 9.31501E-05 97.284 0 0 0 0 0.222003 -5.26841 0.482136 33.06 0.59522 1.91991 0.00020543 95.391 1 S MEQDASSSPSAQV 9.31501E-05 97.284 _LKQLMEQDASpSSPSAQVIGLK_ LKQLMEQDAS(0.022)S(0.595)S(0.383)PSAQVIGLK LKQLMEQDAS(-14.3)S(1.92)S(-1.92)PS(-37.25)AQVIGLK 11 3 770.71855 -0.37268 163840 0 0 0 0 0 0 163840 2318 1601;1602 372;341 372 3509;4627 3962;5250;5251 43862 26887 Mix4_InSol_Tio2_Reinj_1 6614 43867 26888 Mix4_TiO2_1_5 4910 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.861245 8.30616 0.786 8.18626 9.31501E-05 97.284 0 0 0 0 0.746793 5.26841 0.482136 33.06 0.861245 8.30616 0.00020543 95.391 1 S EQDASSSPSAQVI Polo box;Proline-directed 0.00405 9.31501E-05 97.284 _QLMEQDASSpSPSAQVIGLK_ QLMEQDASS(0.127)S(0.861)PS(0.011)AQVIGLK QLMEQDAS(-33.91)S(-8.31)S(8.31)PS(-18.86)AQVIGLK 10 2 1034.9847 -0.049009 194980 40469 0 0 0 0 69805 84703 2319 1601;1602 34;34 34 4504;4557 5117;5176 42721 26257 Mix4_TiO2_Reinj_1_5 7111 42721 26257 Mix4_TiO2_Reinj_1_5 7111 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 1 117.159 1 102.599 0.00171953 102.6 1 117.159 0.00326093 117.16 1 S QGSRQDSWEVVEG CAMK2;CK1 0.042 0.00326093 117.16 _QDpSWEVVEGLR_ QDS(1)WEVVEGLR QDS(117.16)WEVVEGLR 3 2 699.30848 0.12499 295550 86225 0 0 209330 0 0 0 2320 1601;1602 30;30 30 4557 5176 43183 26487 Mix4_TiO2_Reinj_1_5 6520 43183 26487 Mix4_TiO2_Reinj_1_5 6520 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7;Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.923403 10.8118 0 0 0.923403 10.8118 0.103452 46.102 1 S CSSKQGSRQDSWE CK1;CK2;GSK3 0.081 0.103452 46.102 _QGpSRQDSWEVVEGLR_ QGS(0.923)RQDS(0.077)WEVVEGLR QGS(10.81)RQDS(-10.81)WEVVEGLR 3 3 609.27914 -0.26264 88277 0 0 0 88277 0 0 0 2321 1601;1602 425;394 425 5289 6022 51363 31447 Mix4_TiO2_Reinj_1_5 2777 51363 31447 Mix4_TiO2_Reinj_1_5 2777 Q9H4L5;Q9H4L5-5;Q9H4L5-2;Q9H4L5-6 Q9H4L5;Q9H4L5-2 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-2|OSBL3_HUMAN Isoform 1b of Oxyst 1 73.4472 1 64.548 0.00611313 76.735 1 73.4472 0.000736698 94.445 0 0 0.999432 32.4522 0.166962 39.538 1 S NLAEENSRDENRA CK2 0.117 0.000736698 94.445 _SGDNLAEENpSRDENR_ SGDNLAEENS(1)RDENR S(-73.45)GDNLAEENS(73.45)RDENR 10 2 893.35541 0.21721 197200 0.065135 25731 0 0 114680 0 0 56790 2322 1601 251 251 6312;6313;6314 7212;7213;7214 63147 38488 Mix4_TiO2_1_5 5922 63150 38491 Mix4_TiO2_Reinj_1_5 6723 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7 Q9H4L5 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.98266 17.7267 0.98266 17.7267 1.17698E-15 145.6 0 0 0.918806 11.9073 4.36244E-16 152.56 0.105475 -6.02275 1.71476 9.2746 0.519573 6.36079 1.59392 6.3608 1 S VLHRTYSAPAINA CAMK2;CHK1;CHK1/2;PKD 0.003192 4.36244E-16 152.56 _TYpSAPAINAIQGGSFESPK_ T(0.017)Y(0.001)S(0.983)APAINAIQGGSFESPK T(-17.73)Y(-31.28)S(17.73)APAINAIQGGS(-49.5)FES(-49.5)PK 3 3 673.31374 -0.36699 1778800 537550 0 0 1039100 0 0 202120 2323 1601 262 262 6312;6313;6314 7212;7213;7214 63155 38495 Mix4_TiO2_1_5 5375 63150 38491 Mix4_TiO2_Reinj_1_5 6723 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7 Q9H4L5 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.525286 0.542652 0.525286 0.542652 1.17698E-15 145.6 0 0 0.235093 -5.06674 4.36244E-16 152.56 0.372647 -0.541268 1.71476 9.2746 0.120107 -6.36079 1.59392 6.3608 1 S NAIQGGSFESPKK 4.36244E-16 152.56 _TYSAPAINAIQGGpSFESPKK_ T(0.004)Y(0.004)S(0.004)APAINAIQGGS(0.525)FES(0.464)PKK T(-21.51)Y(-21.51)S(-21.51)APAINAIQGGS(0.54)FES(-0.54)PKK 14 3 716.01206 0.55541 230990 230990 0 0 0 0 0 0 2324 1601 265 265 6312;6313;6314 7212;7213;7214 63169 38501 Mix4_TiO2_Reinj_1_5 5880 63150 38491 Mix4_TiO2_Reinj_1_5 6723 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7 Q9H4L5 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.96197 14.0464 0.463586 -0.542652 1.17698E-15 145.6 0 0 0.96197 14.0464 4.36244E-16 152.56 0.422109 0.541268 1.71476 9.2746 0.120107 -6.36079 1.59392 6.3608 1 S QGGSFESPKKEKR CDK1;CDK2;CK1;Proline-directed 0.0057 4.36244E-16 152.56 _TYSAPAINAIQGGSFEpSPKKEK_ TYSAPAINAIQGGS(0.038)FES(0.962)PKKEK T(-48.78)Y(-48.78)S(-39.24)APAINAIQGGS(-14.05)FES(14.05)PKKEK 17 3 801.72458 0.29161 1685700 0 0 0 1685700 0 0 0 2325 1602 251 251 6315 7215 63179 38502 Mix4_TiO2_Reinj_1_5 6599 63179 38502 Mix4_TiO2_Reinj_1_5 6599 Q9H4L5-2;Q9H4L5-6;Q9H4L5-4;Q9H4L5-8 Q9H4L5-2 Q9H4L5-2 >sp|Q9H4L5-2|OSBL3_HUMAN Isoform 1b of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-6|OSBL3_HUMAN Isoform 2b of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-4|OSBL3_HUMAN Isoform 1d of 0.9894 19.7008 0 0 0.9894 19.7008 0.000969744 94.326 1 S VLHRTYSAPAINA CAMK2;CHK1;CHK1/2;PKD 0.003192 0.000969744 94.326 _TYpSAPAINAIQVPK_ T(0.011)YS(0.989)APAINAIQVPK T(-19.7)Y(-72.57)S(19.7)APAINAIQVPK 3 2 776.89218 0.16904 118940 0 0 0 118940 0 0 0 2326 1604 1909 1909 3624 4084 34078 21030 Mix4_TiO2_Reinj_1_1 4653 34078 21030 Mix4_TiO2_Reinj_1_1 4653 Q9H6A9;Q9H6A9-3 Q9H6A9 Q9H6A9 >sp|Q9H6A9|PCX3_HUMAN Pecanex-like protein 3 OS=Homo sapiens GN=PCNXL3 PE=1 SV=2;>sp|Q9H6A9-3|PCX3_HUMAN Isoform 3 of Pecanex-like protein 3 OS=Homo sapiens GN=PCNXL3 0.997133 25.4136 0 0 0 0 0.997133 25.4136 0.00221825 81.547 0 0 0 0 0 0 1 S PGPPPASPIPTEG ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00221825 81.547 _LPGPPPApSPIPTEGPR_ LPGPPPAS(0.997)PIPT(0.003)EGPR LPGPPPAS(25.41)PIPT(-25.41)EGPR 8 2 831.91619 0.087807 99080 0 0 0 99080 0 0 0 2327 1605 318 318 276 316 2616 1640 Mix4_TiO2_Reinj_1_4 6415 2616 1640 Mix4_TiO2_Reinj_1_4 6415 Q9H6S1 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1 0.999662 34.7135 0.995636 23.582 2.06905E-06 90.447 0.999662 34.7135 0.00274551 112.29 1 S EKAILQSWTDNER CK2 0.117 0.00274551 112.29 _AILQpSWTDNER_ AILQS(1)WTDNER AILQS(34.71)WT(-34.71)DNER 5 2 706.81393 -0.065915 304020 0 0 0 304020 0 0 0 2328 1605 300 300 315 358 2960 1800 Mix4_InSol_Tio2_Reinj_1 5045 2962 1802 Mix4_TiO2_Reinj_1_4 4191 Q9H6S1 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1 0.887885 9.89029 0.140617 -7.85879 0.000680924 94.823 0 0 0.234365 -0.699327 6.17919E-05 105.51 0.744374 7.99087 0.055772 54.685 0.887885 9.89029 0.0321226 58.942 1 S ALCHTTSSPLPGD 6.17919E-05 105.51 _ALCHTTpSSPLPGDVK_ ALCHT(0.003)T(0.018)S(0.888)S(0.091)PLPGDVK ALCHT(-24.83)T(-16.9)S(9.89)S(-9.89)PLPGDVK 7 2 831.88149 -0.26946 119580 0 0 0 0 0 29043 90541 2329 1605 301 301 315 358 2957 1797 Mix4_InSol_TiO2_1 5085 2962 1802 Mix4_TiO2_Reinj_1_4 4191 Q9H6S1 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1 0.868787 8.93775 0.858852 7.85879 0.000680924 94.823 0 0 0.861808 8.54342 6.17919E-05 105.51 0.868787 8.93775 0.055772 54.685 0.13763 -7.90245 0.0321226 58.942 1 S LCHTTSSPLPGDV Polo box;Proline-directed 0.00405 6.17919E-05 105.51 _ALCHTTSpSPLPGDVK_ ALCHT(0.001)T(0.02)S(0.111)S(0.869)PLPGDVK ALCHT(-31.94)T(-16.44)S(-8.94)S(8.94)PLPGDVK 8 2 831.88149 -0.64758 337730 70797 0 0 166500 0 100440 0 2330 1605 120 120 1085 1220 10258 6326 Mix4_TiO2_Reinj_1_4 5716 10258 6326 Mix4_TiO2_Reinj_1_4 5716 Q9H6S1;Q9H6S1-3 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1;>sp|Q9H6S1-3|AZI2_HUMAN Isoform Short of 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 0.66875 3.05107 0 0 0.66875 3.05107 2.60133E-12 143.38 1 S NKDNSESLKVLNE 2.60133E-12 143.38 _DNSEpSLKVLNEQLQSK_ DNS(0.331)ES(0.669)LKVLNEQLQSK DNS(-3.05)ES(3.05)LKVLNEQLQS(-143.38)K 5 3 637.97349 -0.25244 244150 0 0 0 244150 0 0 0 2331 1605 353 353 4307;4308 4900;4901 40925 25183 Mix4_TiO2_Reinj_1_4 7669 40924 25181 Mix4_TiO2_Reinj_1_4 7627 Q9H6S1 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1 1 99.2742 1 79.8923 6.30427E-30 216.65 0.466227 2.42272 1.2741 2.4227 1 99.2742 1.64673E-39 238.62 0.998571 34.4647 1.67214E-07 112.8 0.959649 18.5181 0.000287442 86.687 1 S NSWVFPSPPKSSE CDK1;CDK2;GSK3;Proline-directed 0.0057 1.64673E-39 238.62 _NSLEDNSWVFPpSPPK_ NSLEDNSWVFPS(1)PPK NS(-105.3)LEDNS(-99.27)WVFPS(99.27)PPK 12 3 599.60122 0.013032 4485500 1114200 0 0 2715800 0 358020 297420 2332 1607 333 333 6495 7432 65623 40244 Mix4_TiO2_1_3 4922 65623 40244 Mix4_TiO2_1_3 4922 Q9H6Z4;Q9H6Z4-2;Q9H6Z4-3;Q9H6Z4-4 Q9H6Z4 Q9H6Z4 >sp|Q9H6Z4|RANB3_HUMAN Ran-binding protein 3 OS=Homo sapiens GN=RANBP3 PE=1 SV=1;>sp|Q9H6Z4-2|RANB3_HUMAN Isoform Ranbp3-a of Ran-binding protein 3 OS=Homo sapiens GN=RANBP3;>sp|Q9H6Z4-3|RANB3_HUMAN Isoform Ranbp3-b of Ran-binding protein 3 OS=Homo sapiens 0.999997 58.3026 0.999997 58.3026 0.0379152 58.303 0 0 1 S MSERVLSPPKLNE CAMK2;CDK1;CDK2;ERK/MAPK;Proline-directed 0.0034 0.0379152 58.303 _VLpSPPKLNEVSSDANR_ VLS(1)PPKLNEVSSDANR VLS(58.3)PPKLNEVS(-58.3)S(-58.3)DANR 3 3 602.63129 0.39784 36804 36804 0 0 0 0 0 0 2333 1609 1766 1766 450;5460 512;6213 53258 32551 Mix4_TiO2_Reinj_1_5 5410 53257 32550 Mix4_TiO2_Reinj_1_1 4866 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 1 46.1359 1 40.9921 0.146959 40.992 1 46.1359 0.0214829 60.663 1 38.7039 0.127989 38.704 1 2.14674 0.0826528 43.472 1 S KAQRPKSLQLMDN CAMK2 0.042 0.0214829 60.663 _pSLQLMDNR_ S(1)LQLMDNR S(46.14)LQLMDNR 1 2 528.73082 -0.26219 319990 30371 0 0 151060 0 72072 66492 2334 1609 1775 1775 3727 4202;4203 35168 21767 Mix4_TiO2_1_5 5897 35168 21767 Mix4_TiO2_1_5 5897 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.56344 4.2087 0.56344 4.2087 0.000374787 87.621 0.154184 -4.3155 0.000567537 81.843 2 S LMDNRLSPFHGSS PKA;Proline-directed 0.042 0.000374787 87.621 _LpSPFHGSSPPQSTPLpSPPPLTPK_ LS(0.563)PFHGS(0.214)S(0.214)PPQS(0.008)TPLS(0.997)PPPLT(0.003)PK LS(4.21)PFHGS(-4.21)S(-4.21)PPQS(-18.53)T(-33.11)PLS(27.12)PPPLT(-27.12)PK 2 3 843.7324 -0.76185 128040 128040 0 0 0 0 0 0 2335 1609 1780 1780 3727 4202;4203 35169 21769 Mix4_TiO2_Reinj_1_5 6653 35168 21767 Mix4_TiO2_1_5 5897 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.417801 0 0.214168 -4.2087 0.000374787 87.621 0.417801 0 0.000567537 81.843 2 S LSPFHGSSPPQST 0.000374787 87.621 _LSPFHGpSSPPQSTPLpSPPPLTPK_ LS(0.154)PFHGS(0.418)S(0.418)PPQS(0.01)TPLS(0.994)PPPLT(0.006)PK LS(-4.32)PFHGS(0)S(0)PPQS(-16.27)T(-30.93)PLS(21.95)PPPLT(-21.95)PK 7 3 843.7324 -0.19973 0 0 0 0 0 0 0 0 2336 1609 1789 1789 3727 4202;4203 35168 21767 Mix4_TiO2_1_5 5897 35168 21767 Mix4_TiO2_1_5 5897 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.997244 27.1221 0.997244 27.1221 0.000374787 87.621 0.994131 21.9527 0.000567537 81.843 2 S PQSTPLSPPPLTP CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000374787 87.621 _LpSPFHGSSPPQSTPLpSPPPLTPK_ LS(0.563)PFHGS(0.214)S(0.214)PPQS(0.008)TPLS(0.997)PPPLT(0.003)PK LS(4.21)PFHGS(-4.21)S(-4.21)PPQS(-18.53)T(-33.11)PLS(27.12)PPPLT(-27.12)PK 16 3 843.7324 -0.76185 530080 128040 0 0 402050 0 0 0 2337 1609 1834 1834 4328;5396 4922;6141 41121 25295 Mix4_TiO2_Reinj_1_1 5700 41122 25296 Mix4_TiO2_Reinj_1_5 6280 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.973328 15.622 0 0 0 0 0.973328 15.622 0.0132197 67.416 1 S EGSQRNSTELAPP CK1;PKA 0.042 0.0132197 67.416 _NpSTELAPPLPVR_ NS(0.973)T(0.027)ELAPPLPVR NS(15.62)T(-15.62)ELAPPLPVR 2 2 687.34487 0.18897 401000 0 0 0 401000 0 0 0 2338 1609 1802 1802 6093 6954 60231 36476 Mix4_TiO2_Reinj_1_5 6416 60230 36475 Mix4_TiO2_Reinj_1_5 6253 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.361701 0 0 0 0 0 0.361701 0 1.54596E-34 185.84 0.332969 0 4.92054E-07 106.64 0.351892 0 1.71419E-11 124.43 1 S KATRTLSSPSLQT CAMK2;CK1 0.042 1.54596E-34 185.84 _TLpSSPSLQTDGIAATPVPPPPPPK_ T(0.269)LS(0.362)S(0.362)PS(0.008)LQTDGIAATPVPPPPPPK T(-1.29)LS(0)S(0)PS(-16.61)LQT(-47.31)DGIAAT(-130.33)PVPPPPPPK 3 2 1224.6247 1.3982 0 0 0 0 0 0 0 0 2339 1609 1803 1803 6093 6954 60231 36476 Mix4_TiO2_Reinj_1_5 6416 60230 36475 Mix4_TiO2_Reinj_1_5 6253 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.361701 0 0 0 0 0 0.361701 0 1.54596E-34 185.84 0.0532663 -7.95951 4.92054E-07 106.64 0.351892 0 1.71419E-11 124.43 1 S ATRTLSSPSLQTD Polo box;Proline-directed 0.00405 1.54596E-34 185.84 _TLpSSPSLQTDGIAATPVPPPPPPK_ T(0.269)LS(0.362)S(0.362)PS(0.008)LQTDGIAATPVPPPPPPK T(-1.29)LS(0)S(0)PS(-16.61)LQT(-47.31)DGIAAT(-130.33)PVPPPPPPK 4 2 1224.6247 1.3982 0 0 0 0 0 0 0 0 2340 1609 1805 1805 6093 6954 60226 36470 Mix4_InSol_TiO2_1 6653 60230 36475 Mix4_TiO2_Reinj_1_5 6253 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.332969 0 0 0 0 0 0.0253234 -15.6381 1.54596E-34 185.84 0.332969 0 4.92054E-07 106.64 0.214853 -0.86348 1.71419E-11 124.43 1 S RTLSSPSLQTDGI CK1 0.081 1.54596E-34 185.84 _TLpSSPSLQTDGIAATPVPPPPPPK_ T(0.264)LS(0.333)S(0.053)PS(0.333)LQT(0.017)DGIAATPVPPPPPPK T(-1.01)LS(0)S(-7.96)PS(0)LQT(-12.9)DGIAAT(-86.53)PVPPPPPPK 6 3 816.75225 0.081815 0 0 0 0 0 0 0 0 2341 1610 817 817 3789 4281 35977 22269 Mix4_TiO2_1_1 4009 35977 22269 Mix4_TiO2_1_1 4009 Q9H7F0;Q9H7F0-2 Q9H7F0 Q9H7F0 >sp|Q9H7F0|AT133_HUMAN Probable cation-transporting ATPase 13A3 OS=Homo sapiens GN=ATP13A3 PE=1 SV=4;>sp|Q9H7F0-2|AT133_HUMAN Isoform 2 of Probable cation-transporting ATPase 13A3 OS=Homo sapiens GN=ATP13A3 0.999967 44.8136 0.999967 44.8136 0.0187756 55.236 1 S VKLVHDSLEDLQM CK2 0.117 0.0187756 55.236 _LVHDpSLEDLQM(ox)TR_ LVHDS(1)LEDLQMTR LVHDS(44.81)LEDLQMT(-44.81)R 5 2 826.87112 0.50159 0 0 0 0 0 0 0 0 2342 1612 187 187 3327 3765 31453 19484 Mix4_TiO2_Reinj_1_4 8469 31453 19484 Mix4_TiO2_Reinj_1_4 8469 Q9H8G2 Q9H8G2 Q9H8G2 >sp|Q9H8G2|CI082_HUMAN Uncharacterized protein C9orf82 OS=Homo sapiens GN=C9orf82 PE=1 SV=2 1 37.5268 1 24.0393 0.363245 24.039 1 24.7612 0.351664 24.761 1 37.5268 0.146872 37.527 1 S EQLELLSEKKILK 0.146872 37.527 _LCQEQLELLpSEKK_ LCQEQLELLS(1)EKK LCQEQLELLS(37.53)EKK 10 2 849.41262 -0.42483 4179200 1094900 37836 0 3046400 0 0 0 2343 1613 114 114 4366 4965 41417 25462 Mix4_InSol_TiO2_1 7110 41417 25462 Mix4_InSol_TiO2_1 7110 Q9H8M9 Q9H8M9 Q9H8M9 >sp|Q9H8M9|F176A_HUMAN Protein FAM176A OS=Homo sapiens GN=FAM176A PE=2 SV=1 0.99975 36.0139 0.999209 31.0153 0.00143454 99.907 0 0 0.998733 28.965 0.00173077 102.71 0.99975 36.0139 0.00216288 106.79 0.994544 22.6072 0.0379184 52.218 1 S NKNVFTSAEELER CK2 0.117 0.00216288 106.79 _NVFTpSAEELER_ NVFTS(1)AEELER NVFT(-36.01)S(36.01)AEELER 5 2 687.80049 0.35047 618740 120360 0 0 322520 0 100410 75448 2344 1619 6 6 122 143 1248 794 Mix4_TiO2_1_3 5356 1246 792 Mix4_InSol_TiO2_1 6487 Q9H9E3;Q9H9E3-2 Q9H9E3 Q9H9E3 >sp|Q9H9E3|COG4_HUMAN Conserved oligomeric Golgi complex subunit 4 OS=Homo sapiens GN=COG4 PE=1 SV=2;>sp|Q9H9E3-2|COG4_HUMAN Isoform Cog4S of Conserved oligomeric Golgi complex subunit 4 OS=Homo sapiens GN=COG4 0.9995 33.0128 0.9995 33.0128 0.00655083 73.107 0.97016 15.1215 0.0645721 56.565 0.793439 5.84466 7.68087E-07 103.01 0.995972 23.9319 0.000266153 90.877 1 S _MADLDSPPKLSG CDK1;CDK2;Proline-directed 0.0057 7.68087E-07 103.01 _(ac)ADLDpSPPKLSGVQQPSEGVGGGR_ ADLDS(1)PPKLSGVQQPSEGVGGGR ADLDS(33.01)PPKLS(-33.01)GVQQPS(-70.67)EGVGGGR 5 2 1187.0577 1.9797 944960 288850 0 0 490190 0 96221 69696 2345 1621 918 918 307 350 2887 1756 Mix4_TiO2_1_5 6046 2888 1757 Mix4_TiO2_Reinj_1_5 6912 Q9HAU0-4;Q9HAU0-2;Q9HAU0;Q9HAU0-5 Q9HAU0-4 Q9HAU0-4 >sp|Q9HAU0-4|PKHA5_HUMAN Isoform 4 of Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens GN=PLEKHA5;>sp|Q9HAU0-2|PKHA5_HUMAN Isoform 2 of Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens GN=PLEKHA5;>sp|Q9HAU0|PKH 0.808523 8.19137 0.808523 8.19137 0.320219 36.305 0.477994 0 0.00148055 80.855 0 0 0.323395 1.21733 1.06526 14.348 1 S VPPRAKSPTPESS CAMK2;Proline-directed 0.042 0.00148055 80.855 _AKpSPTPESSTIASYVTLR_ AKS(0.809)PT(0.123)PES(0.023)S(0.023)T(0.023)IASYVTLR AKS(8.19)PT(-8.19)PES(-15.5)S(-15.5)T(-15.5)IAS(-36.31)Y(-36.31)VT(-36.31)LR 3 3 663.32939 -0.10991 105010 105010 0 0 0 0 0 0 2346 1622 826 826 5099 5800 49295 30070 Mix4_TiO2_Reinj_1_5 9019 49295 30070 Mix4_TiO2_Reinj_1_5 9019 Q9HAV4 Q9HAV4 Q9HAV4 >sp|Q9HAV4|XPO5_HUMAN Exportin-5 OS=Homo sapiens GN=XPO5 PE=1 SV=1 1 132.304 0 0 1 132.304 5.84955E-11 132.3 1 S LLELNDSPVFKTV NEK6;Proline-directed 0.05 5.84955E-11 132.3 _SAILGLPQPLLELNDpSPVFK_ SAILGLPQPLLELNDS(1)PVFK S(-132.3)AILGLPQPLLELNDS(132.3)PVFK 16 2 1116.0898 0.88893 96879 0 0 0 96879 0 0 0 2347 1622 416 416 5946 6780 58570 35515 Mix4_TiO2_Reinj_1_5 2775 58570 35515 Mix4_TiO2_Reinj_1_5 2775 Q9HAV4 Q9HAV4 Q9HAV4 >sp|Q9HAV4|XPO5_HUMAN Exportin-5 OS=Homo sapiens GN=XPO5 PE=1 SV=1 0.986432 18.7224 0 0 0.986432 18.7224 0.0100632 59.224 1 S FPSKTDSPSCEYS CK1;Proline-directed 0.05 0.0100632 59.224 _TDpSPSCEYSR_ T(0.013)DS(0.986)PSCEYSR T(-18.72)DS(18.72)PS(-34.79)CEY(-59.22)S(-59.22)R 3 2 641.2263 0.60105 223640 5.7793 0 0 0 223640 0 0 0 2348 1624 104 104 2781 3170 26615 16623 Mix4_InSol_Tio2_Reinj_1 2052 26614 16622 Mix4_InSol_TiO2_1 2000 Q9HAZ1 Q9HAZ1 Q9HAZ1 >sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.860721 8.63353 0.771595 5.41197 0.0409252 49.928 0.860721 8.63353 0.0487201 47.459 1 S RIHCSKSSVRSRR GSK3 0.081 0.0409252 49.928 _IHCSKpSSVR_ IHCS(0.021)KS(0.861)S(0.118)VR IHCS(-16.05)KS(8.63)S(-8.63)VR 6 2 577.26282 -0.48061 92618 0 0 0 0 0 45882 46736 2349 1624 138 138 5366 6109 52190 31928 Mix4_TiO2_Reinj_1_4 6364 52188 31926 Mix4_TiO2_1_4 5725 Q9HAZ1 Q9HAZ1 Q9HAZ1 >sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 1 119.348 1 160.367 1.80877E-26 190.75 0 0 1 119.348 4.35961E-21 159.58 0 0 0 0 1 S RRKRSRSIEDDEE CAMK2;CK2;PKA;PKA/AKT 0.001764 1.80877E-26 190.75 _pSIEDDEEGHLICQSGDVLR_ S(1)IEDDEEGHLICQSGDVLR S(119.35)IEDDEEGHLICQS(-119.35)GDVLR 1 2 1126.4805 -0.047843 2846900 311850 0 0 2535100 0 0 0 2350 1629 9 9 3884 4410 36834 22699 Mix4_TiO2_Reinj_1_4 2679 36834 22699 Mix4_TiO2_Reinj_1_4 2679 Q9HCD5 Q9HCD5 Q9HCD5 >sp|Q9HCD5|NCOA5_HUMAN Nuclear receptor coactivator 5 OS=Homo sapiens GN=NCOA5 PE=1 SV=2 0.734213 4.41459 0.390167 2.83161 0.756805 2.8316 0 0 0.734213 4.41459 0.00645549 79.772 0 0 0 0 1 S TAPSRPSPTRRDP CDK1;CDK2;CK1;PKA;Proline-directed 0.0057 0.00645549 79.772 _(ac)M(ox)NTAPSRPpSPTR_ MNTAPSRPS(0.734)PT(0.266)R MNT(-79.77)APS(-38.48)RPS(4.41)PT(-4.41)R 9 2 726.81869 0.69969 123470 0 0 0 123470 0 0 0 2351 1630 1393 1393 6520 7460 65868 40349 Mix4_TiO2_Reinj_1_1 4993 65868 40349 Mix4_TiO2_Reinj_1_1 4993 Q9HCE0;Q9HCE0-2 Q9HCE0 Q9HCE0 >sp|Q9HCE0|K1632_HUMAN UPF0493 protein KIAA1632 OS=Homo sapiens GN=KIAA1632 PE=2 SV=2;>sp|Q9HCE0-2|K1632_HUMAN Isoform 2 of UPF0493 protein KIAA1632 OS=Homo sapiens GN=KIAA1632 0.333237 0 0.138261 -6.88194 0.593694 41.69 0 0 0.333237 0 0.119073 57.263 1 S TPGYLTSPELHKE Proline-directed 0.05 0.119073 57.263 _VPAEGSEGLPESHSGTPGpYLTSPELHK_ VPAEGSEGLPESHSGTPGY(0.333)LT(0.333)S(0.333)PELHK VPAEGS(-57.26)EGLPES(-41.41)HS(-36.95)GT(-32.3)PGY(0)LT(0)S(0)PELHK 22 3 952.77444 0.40277 0 0 0 0 0 0 0 0 2352 1633 1307 1307 1455 1636 13658 8343 Mix4_TiO2_1_1 4550 13658 8343 Mix4_TiO2_1_1 4550 Q9HCF4-3;Q9HCF4 Q9HCF4-3 Q9HCF4-3 >sp|Q9HCF4-3|ALO17_HUMAN Isoform 3 of Protein ALO17 OS=Homo sapiens GN=KIAA1618;>sp|Q9HCF4|ALO17_HUMAN Protein ALO17 OS=Homo sapiens GN=KIAA1618 PE=1 SV=2 1 82.9387 1 82.9387 3.22324E-49 252.66 0.999965 44.6106 0.0193761 63.828 0 0 0.999407 32.2658 0.0183365 64.745 1 S EAAELLSEPEEES CK2 0.117 3.22324E-49 252.66 _EDQEAAELLpSEPEEESER_ EDQEAAELLS(1)EPEEESER EDQEAAELLS(82.94)EPEEES(-82.94)ER 10 2 1085.439 0.91576 250170 0.79969 222520 15482 0 0 12169 0 0 2353 1634 714 714 1245;1246 1401;1402 11677 7182 Mix4_TiO2_1_5 5349 11677 7182 Mix4_TiO2_1_5 5349 Q9HCJ0-2;Q9HCJ0 Q9HCJ0-2 Q9HCJ0-2 >sp|Q9HCJ0-2|TNR6C_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6C protein OS=Homo sapiens GN=TNRC6C;>sp|Q9HCJ0|TNR6C_HUMAN Trinucleotide repeat-containing gene 6C protein OS=Homo sapiens GN=TNRC6C PE=1 SV=3 0.949987 12.7864 0.949987 12.7864 1.52133E-12 139.44 0 0 0 0 0 0 0 0 1 S TGWEEPSPPSIRR Proline-directed 0.05 1.52133E-12 139.44 _DSSEATGWEEPpSPPSIR_ DSSEATGWEEPS(0.95)PPS(0.05)IR DS(-83.99)S(-83.99)EAT(-91.46)GWEEPS(12.79)PPS(-12.79)IR 12 2 962.90166 0.44862 104670 104670 0 0 0 0 0 0 2354 1634 717 717 1245;1246 1401;1402 11686 7184 Mix4_TiO2_1_3 1605 11677 7182 Mix4_TiO2_1_5 5349 Q9HCJ0-2;Q9HCJ0 Q9HCJ0-2 Q9HCJ0-2 >sp|Q9HCJ0-2|TNR6C_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6C protein OS=Homo sapiens GN=TNRC6C;>sp|Q9HCJ0|TNR6C_HUMAN Trinucleotide repeat-containing gene 6C protein OS=Homo sapiens GN=TNRC6C PE=1 SV=3 0.704562 7.81892 0.704562 7.81892 1.52133E-12 139.44 0 0 0 0 0 0 0 0 1 S EEPSPPSIRRKME CK1 0.081 1.52133E-12 139.44 _DSSEATGWEEPSPPpSIRR_ DS(0.06)S(0.06)EAT(0.06)GWEEPS(0.116)PPS(0.705)IRR DS(-10.72)S(-10.72)EAT(-10.72)GWEEPS(-7.82)PPS(7.82)IRR 15 2 1040.9522 0.68776 158170 158170 0 0 0 0 0 0 2355 1635 314 314 1227 1381 11509 7038 Mix4_TiO2_1_4 7203 11510 7039 Mix4_TiO2_1_4 7238 Q9HCN4 Q9HCN4 Q9HCN4 >sp|Q9HCN4|GPN1_HUMAN GPN-loop GTPase 1 OS=Homo sapiens GN=GPN1 PE=1 SV=1 0.991883 20.8963 0.991883 20.8963 0.0015596 86.702 0.951567 12.9434 0.0203974 64.428 1 S TAKDSLSPVLHPS Proline-directed 0.05 0.0015596 86.702 _DSLpSPVLHPSDLILTR_ DS(0.008)LS(0.992)PVLHPSDLILTR DS(-20.9)LS(20.9)PVLHPS(-46.14)DLILT(-46.14)R 4 3 614.98355 -0.034728 649940 166060 0 0 483880 0 0 0 2356 1635 338 338 2496 2836 23485 14611 Mix4_TiO2_Reinj_1_4 4340 23485 14611 Mix4_TiO2_Reinj_1_4 4340 Q9HCN4 Q9HCN4 Q9HCN4 >sp|Q9HCN4|GPN1_HUMAN GPN-loop GTPase 1 OS=Homo sapiens GN=GPN1 PE=1 SV=1 0.999154 30.725 0.998555 31.0355 0.0152052 63.061 0 0 0.999154 30.725 9.03514E-22 164.12 0 0 0 0 1 S EDEEADSDTDDID CK2 0.117 9.03514E-22 164.12 _GTLDEEDEEADpSDTDDIDHR_ GTLDEEDEEADS(0.999)DT(0.001)DDIDHR GT(-130.99)LDEEDEEADS(30.73)DT(-30.73)DDIDHR 12 3 786.2906 -0.0081709 2872100 424120 0 0 2447900 0 0 0 2357 1636 361 361 1172 1317 10972 6726 Mix4_TiO2_Reinj_1_4 2664 10972 6726 Mix4_TiO2_Reinj_1_4 2664 Q9HCP0;Q9HCP0-2 Q9HCP0 Q9HCP0 >sp|Q9HCP0|KC1G1_HUMAN Casein kinase I isoform gamma-1 OS=Homo sapiens GN=CSNK1G1 PE=1 SV=1;>sp|Q9HCP0-2|KC1G1_HUMAN Isoform 1S of Casein kinase I isoform gamma-1 OS=Homo sapiens GN=CSNK1G1 1 45.6085 0 0 1 45.6085 0.0511861 45.609 1 S THRDRPSQQQPLR PKA 0.042 0.0511861 45.609 _DRPpSQQQPLR_ DRPS(1)QQQPLR DRPS(45.61)QQQPLR 4 2 652.80898 0.28009 114590 0 0 0 114590 0 0 0 2358 1637 45 45 4901 5573 47058 28775 Mix4_TiO2_Reinj_1_4 7434 47058 28775 Mix4_TiO2_Reinj_1_4 7434 Q9NP56 Q9NP56 Q9NP56 >sp|Q9NP56|PDE7B_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 7B OS=Homo sapiens GN=PDE7B PE=1 SV=1 0.996464 24.4996 0.949677 12.7581 0.504297 12.758 0.996464 24.4996 0.00676127 61.005 1 S RAERRGSYPFIDF CAMK2;PKA 0.004788 0.00676127 61.005 _RGpSYPFIDFR_ RGS(0.996)Y(0.004)PFIDFR RGS(24.5)Y(-24.5)PFIDFR 3 2 669.30554 -0.41721 221310 31196 0 0 190110 0 0 0 2359 1638 448 448 1276 1439 12031 7374 Mix4_TiO2_2_4 5998 12031 7374 Mix4_TiO2_2_4 5998 Q9NPF5 Q9NPF5 Q9NPF5 >sp|Q9NPF5|DMAP1_HUMAN DNA methyltransferase 1-associated protein 1 OS=Homo sapiens GN=DMAP1 PE=1 SV=1 0.553944 0.940766 0 0 0.553944 0.940766 0.019016 65.569 0 0 1 S APLTPNSRKRRES 0.019016 65.569 _DTIIDVVGAPLTPNpSR_ DTIIDVVGAPLT(0.446)PNS(0.554)R DT(-65.57)IIDVVGAPLT(-0.94)PNS(0.94)R 15 2 874.43494 1.2179 22699 0 22699 0 0 0 0 0 2360 1641 825 825 3460 3906 32573 20205 Mix4_TiO2_Reinj_1_5 6459 32573 20205 Mix4_TiO2_Reinj_1_5 6459 Q9NPR2 Q9NPR2 Q9NPR2 >sp|Q9NPR2|SEM4B_HUMAN Semaphorin-4B OS=Homo sapiens GN=SEMA4B PE=1 SV=3 0.999972 45.5065 0.995599 23.5458 0.275312 23.546 0.999972 45.5065 0.0514945 45.507 1 S PRVRLGSEIRDSV CAMK2;PKA/AKT 0.001764 0.0514945 45.507 _LGpSEIRDSVV_ LGS(1)EIRDSVV LGS(45.51)EIRDS(-45.51)VV 3 2 577.77629 -0.65544 124620 29420 0 0 95202 0 0 0 2361 1642 359 359 6411 7333 64721 39701 Mix4_TiO2_1_4 3015 64721 39701 Mix4_TiO2_1_4 3015 Q9NQ55;Q9NQ55-2 Q9NQ55 Q9NQ55 >sp|Q9NQ55|SSF1_HUMAN Suppressor of SWI4 1 homolog OS=Homo sapiens GN=PPAN PE=1 SV=1;>sp|Q9NQ55-2|SSF1_HUMAN Isoform 2 of Suppressor of SWI4 1 homolog OS=Homo sapiens GN=PPAN 1 75.618 1 75.618 0.00268168 83.964 0 0 0 0 1 74.2363 0.00899475 74.236 1 70.3936 0.0107576 72.567 1 S KARVGGSDEEASG CK2 0.117 0.00268168 83.964 _VGGpSDEEASGIPSR_ VGGS(1)DEEASGIPSR VGGS(75.62)DEEAS(-75.62)GIPS(-83.96)R 4 2 720.80376 -0.064582 213090 106780 0 0 0 0 66486 39832 2362 1643 11 11 3839 4339;4340 36384 22462 Mix4_InSol_Tio2_Reinj_1 6947 36386 22465 Mix4_TiO2_Reinj_1_1 6013 Q9NQC3-2;Q9NQC3;Q9NQC3-4;Q9NQC3-5 Q9NQC3-2 Q9NQC3-2 >sp|Q9NQC3-2|RTN4_HUMAN Isoform Foocen-M of Reticulon-4 OS=Homo sapiens GN=RTN4;>sp|Q9NQC3|RTN4_HUMAN Reticulon-4 OS=Homo sapiens GN=RTN4 PE=1 SV=2;>sp|Q9NQC3-4|RTN4_HUMAN Isoform 4 of Reticulon-4 OS=Homo sapiens GN=RTN4;>sp|Q9NQC3-5|RTN4_HUMAN Isoform RTN 0.458473 0 0.241657 -0.558391 0.000543483 80.571 0 0 0.0208745 -15.4907 0.000505605 81.846 0.057667 -10.5155 0.152538 52.097 0.458473 0 0.00494421 75.228 1 S DQSPLVSSSDSPP CK1;CK2;GSK3 0.081 0.000505605 81.846 _(ac)M(ox)EDLDQSPLVpSSSDSPPRPQPAFK_ MEDLDQSPLVS(0.458)S(0.458)S(0.071)DS(0.012)PPRPQPAFK MEDLDQS(-33.36)PLVS(0)S(0)S(-8.09)DS(-15.92)PPRPQPAFK 11 3 922.74912 -0.044354 0 0 0 0 0 0 0 0 2363 1643 12 12 3839 4339;4340 36384 22462 Mix4_InSol_Tio2_Reinj_1 6947 36386 22465 Mix4_TiO2_Reinj_1_1 6013 Q9NQC3-2;Q9NQC3;Q9NQC3-4;Q9NQC3-5 Q9NQC3-2 Q9NQC3-2 >sp|Q9NQC3-2|RTN4_HUMAN Isoform Foocen-M of Reticulon-4 OS=Homo sapiens GN=RTN4;>sp|Q9NQC3|RTN4_HUMAN Reticulon-4 OS=Homo sapiens GN=RTN4 PE=1 SV=2;>sp|Q9NQC3-4|RTN4_HUMAN Isoform 4 of Reticulon-4 OS=Homo sapiens GN=RTN4;>sp|Q9NQC3-5|RTN4_HUMAN Isoform RTN 0.458473 0 0.241657 -0.558391 0.000543483 80.571 0 0 0.119963 -7.89638 0.000505605 81.846 0.193717 -4.68024 0.152538 52.097 0.458473 0 0.00494421 75.228 1 S QSPLVSSSDSPPR NEK6 0.076 0.000505605 81.846 _(ac)M(ox)EDLDQSPLVpSSSDSPPRPQPAFK_ MEDLDQSPLVS(0.458)S(0.458)S(0.071)DS(0.012)PPRPQPAFK MEDLDQS(-33.36)PLVS(0)S(0)S(-8.09)DS(-15.92)PPRPQPAFK 12 3 922.74912 -0.044354 0 0 0 0 0 0 0 0 2364 1643 15 15 3839 4339;4340 36386 22465 Mix4_TiO2_Reinj_1_1 6013 36386 22465 Mix4_TiO2_Reinj_1_1 6013 Q9NQC3-2;Q9NQC3;Q9NQC3-4;Q9NQC3-5 Q9NQC3-2 Q9NQC3-2 >sp|Q9NQC3-2|RTN4_HUMAN Isoform Foocen-M of Reticulon-4 OS=Homo sapiens GN=RTN4;>sp|Q9NQC3|RTN4_HUMAN Reticulon-4 OS=Homo sapiens GN=RTN4 PE=1 SV=2;>sp|Q9NQC3-4|RTN4_HUMAN Isoform 4 of Reticulon-4 OS=Homo sapiens GN=RTN4;>sp|Q9NQC3-5|RTN4_HUMAN Isoform RTN 0.88354 9.44165 0.516721 3.55652 0.000543483 80.571 0 0 0.88354 9.44165 0.000505605 81.846 0.649345 6.46883 0.152538 52.097 0.833205 7.84616 0.00494421 75.228 1 S LVSSSDSPPRPQP CDK1;CDK2;CK1;Proline-directed 0.0057 0.000505605 81.846 _(ac)M(ox)EDLDQSPLVSSSDpSPPRPQPAFK_ MEDLDQSPLVS(0.002)S(0.014)S(0.1)DS(0.884)PPRPQPAFK MEDLDQS(-62.46)PLVS(-26.35)S(-18.02)S(-9.44)DS(9.44)PPRPQPAFK 15 3 922.74912 0.45017 1792100 140000 0 0 660770 0 552100 439230 2365 1643 181 181 4899 5571 47048 28770 Mix4_TiO2_Reinj_1_4 8974 47048 28770 Mix4_TiO2_Reinj_1_4 8974 Q9NQC3-2 Q9NQC3-2 Q9NQC3-2 >sp|Q9NQC3-2|RTN4_HUMAN Isoform Foocen-M of Reticulon-4 OS=Homo sapiens GN=RTN4 0.452153 0 0.452153 0 0.00512972 77.622 1 S APKRRGSSGSVVV CAMK2;PKA 0.003024 0.00512972 77.622 _RGpSSGSVVVDLLYWR_ RGS(0.452)S(0.452)GS(0.096)VVVDLLYWR RGS(0)S(0)GS(-6.74)VVVDLLY(-77.62)WR 3 3 591.96097 0.33086 0 0 0 0 0 0 0 0 2366 1643 182 182 4899 5571 47048 28770 Mix4_TiO2_Reinj_1_4 8974 47048 28770 Mix4_TiO2_Reinj_1_4 8974 Q9NQC3-2 Q9NQC3-2 Q9NQC3-2 >sp|Q9NQC3-2|RTN4_HUMAN Isoform Foocen-M of Reticulon-4 OS=Homo sapiens GN=RTN4 0.452153 0 0.452153 0 0.00512972 77.622 1 S PKRRGSSGSVVVD CAMK2 0.042 0.00512972 77.622 _RGpSSGSVVVDLLYWR_ RGS(0.452)S(0.452)GS(0.096)VVVDLLYWR RGS(0)S(0)GS(-6.74)VVVDLLY(-77.62)WR 4 3 591.96097 0.33086 0 0 0 0 0 0 0 0 2367 1644 335 335 2309 2612 21366 13094 Mix4_InSol_Tio2_Reinj_2 5932 21379 13115 Mix4_TiO2_Reinj_1_5 8642 Q9NQQ7;Q9NQQ7-2 Q9NQQ7 Q9NQQ7 >sp|Q9NQQ7|S35C2_HUMAN Solute carrier family 35 member C2 OS=Homo sapiens GN=SLC35C2 PE=1 SV=2;>sp|Q9NQQ7-2|S35C2_HUMAN Isoform 2 of Solute carrier family 35 member C2 OS=Homo sapiens GN=SLC35C2 0.979459 16.7837 0.86125 7.92895 9.20845E-05 116.68 0.5 0 0.843893 6.5415 0.43831 -1.07716 3.75027E-05 123.85 0 0 0.979459 16.7837 0.0909211 41.226 1 S ALKGLGSSPDLEL CK2 0.117 3.75027E-05 123.85 _GLGpSSPDLELLLR_ GLGS(0.979)S(0.021)PDLELLLR GLGS(16.78)S(-16.78)PDLELLLR 4 2 725.37108 0.39947 271050 212170 8152 0 0 0 0 50733 2368 1644 336 336 2309 2612 21378 13113 Mix4_TiO2_Reinj_1_5 8367 21379 13115 Mix4_TiO2_Reinj_1_5 8642 Q9NQQ7;Q9NQQ7-2 Q9NQQ7 Q9NQQ7 >sp|Q9NQQ7|S35C2_HUMAN Solute carrier family 35 member C2 OS=Homo sapiens GN=SLC35C2 PE=1 SV=2;>sp|Q9NQQ7-2|S35C2_HUMAN Isoform 2 of Solute carrier family 35 member C2 OS=Homo sapiens GN=SLC35C2 0.998526 28.3095 0.608383 1.91315 9.20845E-05 116.68 0.5 0 0.843893 6.5415 0.998526 28.3095 3.75027E-05 123.85 0 0 0.0205408 -16.7837 0.0909211 41.226 1 S LKGLGSSPDLELL NEK6;Polo box;Proline-directed 0.00405 3.75027E-05 123.85 _GLGSpSPDLELLLR_ GLGS(0.001)S(0.999)PDLELLLR GLGS(-28.31)S(28.31)PDLELLLR 5 2 725.37108 0.13667 1649900 135560 8152 0 1506200 0 0 0 2369 1645 142 142 0 0;1;2;3;4 13 7 Mix4_TiO2_1_5 5801 4 2 Mix4_TiO2_Reinj_1_5 5788 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.491239 0 0.491239 0 3.2373E-18 143.76 0.110166 -9.02078 1.742E-18 149.73 0 0 0.0269107 -15.4343 0.000107956 91.637 1 S MALAAPSSPTPES 1.742E-18 149.73 _AAAAAAAATMALAAPpSSPTPESPTM(ox)LTK_ AAAAAAAATMALAAPS(0.491)S(0.491)PT(0.017)PESPTMLTK AAAAAAAAT(-58.93)MALAAPS(0)S(0)PT(-14.57)PES(-31.91)PT(-39.24)MLT(-46.35)K 16 3 899.09547 0.9207 0 0 0 0 0 0 0 0 2370 1645 143 143 0 0;1;2;3;4 0 0 Mix4_InSol_Tio2_Reinj_1 7455 4 2 Mix4_TiO2_Reinj_1_5 5788 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.940484 14.6241 0.845036 7.38823 3.2373E-18 143.76 0.879277 9.02078 1.742E-18 149.73 0 0 0.940484 14.6241 0.000107956 91.637 1 S ALAAPSSPTPESP ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 1.742E-18 149.73 _AAAAAAAATMALAAPSpSPTPESPTMLTK_ AAAAAAAATMALAAPS(0.027)S(0.94)PT(0.032)PESPTMLTK AAAAAAAAT(-76.39)MALAAPS(-15.43)S(14.62)PT(-14.62)PES(-42.74)PT(-42.08)MLT(-41.42)K 17 3 893.76383 -0.014555 1238800 288010 0 0 665210 0 0 285540 2371 1645 148 148 0 0;1;2;3;4 19 9 Mix4_TiO2_Reinj_1_5 6475 19 9 Mix4_TiO2_Reinj_1_5 6475 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.740419 7.746 0.372901 -0.958293 0.0046668 76.982 0.740419 7.746 3.47748E-12 126.64 0 0 5.00315E-05 -42.7411 0.000107956 91.637 2 S SSPTPESPTMLTK ERK/MAPK;Proline-directed;WW GroupIV 0.000145 3.47748E-12 126.64 _AAAAAAAATMALAAPSpSPTPEpSPTM(ox)LTK_ AAAAAAAATMALAAPS(0.064)S(0.856)PT(0.092)PES(0.74)PT(0.124)MLT(0.124)K AAAAAAAAT(-98.16)MALAAPS(-11.19)S(10.24)PT(-10.24)PES(7.75)PT(-7.75)MLT(-7.75)K 22 3 925.75091 -0.045833 374040 0 0 0 374040 0 0 0 2372 1645 275 275 1230;1231;2704 1384;1385;3079;3080 11531 7057 Mix4_TiO2_Reinj_1_5 6075 11528 7053 Mix4_TiO2_1_5 5272 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 1 101.209 1 146.906 3.74574E-09 168.01 1 75.9038 0.00451894 75.904 1 101.209 0.000542327 101.21 0.000121833 -38.1759 0.310712 38.176 1.53281E-05 -48.0773 0.126441 48.077 1 S SPAFPDSPWRERV CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.74574E-09 168.01 _DSPAFPDpSPWRER_ DSPAFPDS(1)PWRER DS(-101.21)PAFPDS(101.21)PWRER 8 2 820.34867 0.2341 3648200 958060 88836 0 2601300 0 0 0 2373 1645 253 253 2378 2691 22062 13751 Mix4_InSol_Tio2_Reinj_1 1569 22062 13751 Mix4_InSol_Tio2_Reinj_1 1569 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.980127 17.2831 0.816043 8.69003 0.186398 32.763 0.980127 17.2831 0.0749165 43.893 1 S GVGTGRSASKLRI 0.0749165 43.893 _GQGVGTGRpSASK_ GQGVGT(0.018)GRS(0.98)AS(0.002)K GQGVGT(-17.28)GRS(17.28)AS(-28.01)K 9 2 592.77461 0.49055 88718 0 0 0 0 0 45061 43657 2374 1645 306 306 2653;5947 3017;3018;6781;6782 24741 15332 Mix4_TiO2_Reinj_1_5 4777 24737 15325 Mix4_TiO2_1_5 4238 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 1 79.439 0.999927 43.463 1.48617E-16 170.3 0.598135 6.56962 1.53242 22.288 1 79.439 2.29341E-16 167.24 0 0 0.986436 23.3888 4.06126E-14 156.22 0.615284 6.81087 5.07042E-16 156.74 1 S SQSVRHSPIAPSS CK1;PKA;Proline-directed 0.042 1.48617E-16 170.3 _HpSPIAPSSPSPQVLAQK_ HS(1)PIAPSSPSPQVLAQK HS(79.44)PIAPS(-95.18)S(-94.8)PS(-79.44)PQVLAQK 2 2 912.45621 -0.27814 9313800 1515300 104010 0 5205400 0 1279900 1209200 2375 1645 311 311 2653;5947 3017;3018;6781;6782 58572 35516 Mix4_InSol_TiO2_1 4991 24772 15340 Mix4_TiO2_Reinj_1_5 4666 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.744208 5.75647 0.674967 3.25783 1.48617E-16 170.3 0.0035321 -22.2877 1.53242 22.288 0.499974 0 3.7531E-09 127.16 0 0 0.744208 5.75647 0.250339 46.068 0.492147 0.650046 5.07042E-16 156.74 2 S HSPIAPSSPSPQV 3.7531E-09 127.16 _TDSQSVRHpSPIAPpSSPSPQVLAQK_ T(0.164)DS(0.164)QS(0.164)VRHS(0.509)PIAPS(0.744)S(0.2)PS(0.056)PQVLAQK T(-4.96)DS(-4.96)QS(-4.96)VRHS(4.96)PIAPS(5.76)S(-5.76)PS(-11.37)PQVLAQK 14 3 893.08427 -0.22542 36789 8913.1 0 0 0 0 27876 0 2376 1645 312 312 2653;5947 3017;3018;6781;6782 24743 15335 Mix4_TiO2_Reinj_1_5 4904 24737 15325 Mix4_TiO2_1_5 4238 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.855102 8.32282 0.827232 8.17836 6.99683E-06 104.84 0.0035321 -22.2877 1.53242 22.288 0.855102 8.32282 2.29341E-16 167.24 0 0 0.430899 -0.469027 0.250339 46.068 0.598692 4.10685 1.69174 17.217 1 S SPIAPSSPSPQVL ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 1.48617E-16 170.3 _HSPIAPSpSPSPQVLAQK_ HSPIAPS(0.126)S(0.855)PS(0.019)PQVLAQK HS(-46.08)PIAPS(-8.32)S(8.32)PS(-16.52)PQVLAQK 8 3 608.6399 0.073107 892350 165100 0 0 727250 0 0 0 2377 1645 314 314 2653;5947 3017;3018;6781;6782 24737 15325 Mix4_TiO2_1_5 4238 24737 15325 Mix4_TiO2_1_5 4238 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.97837 16.7757 0.97837 16.7757 1.48617E-16 170.3 0.0035321 -22.2877 1.53242 22.288 0.60639 1.9735 2.29341E-16 167.24 0 0 0.97289 18.1275 4.06126E-14 156.22 0.913195 10.3692 5.07042E-16 156.74 1 S IAPSSPSPQVLAQ CK1;Proline-directed 0.05 1.48617E-16 170.3 _HSPIAPSSPpSPQVLAQK_ HSPIAPS(0.001)S(0.021)PS(0.978)PQVLAQK HS(-71.09)PIAPS(-29.6)S(-16.78)PS(16.78)PQVLAQK 10 2 912.45621 0.012376 1924100 306540 0 0 843490 0 406360 367710 2378 1645 263 263 2703;2704 3078;3079;3080 25524 15776 Mix4_TiO2_Reinj_1_5 3023 25523 15775 Mix4_TiO2_Reinj_1_1 2591 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 1 61.5471 1 61.5471 0.0078495 61.547 1 55.3817 0.0237007 55.382 1 61.5471 0.00585167 66.541 0 0 1 61.5437 0.00785089 61.544 1 45.4715 0.00805297 61.039 1 S LRIAQVSPGPRDS Proline-directed 0.05 0.00585167 66.541 _IAQVpSPGPR_ IAQVS(1)PGPR IAQVS(61.55)PGPR 5 2 502.74987 0.15048 10080000 1674700 377320 0 5820200 0 1282500 924890 2379 1645 421 421 4404 5010 41950 25865 Mix4_TiO2_Reinj_1_3 2523 41951 25866 Mix4_TiO2_Reinj_1_5 2543 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.998403 27.9627 0.997667 26.7933 6.75721E-13 149 0.998403 27.9627 2.85166E-16 165.13 1 S PKPAASSPETPSA Polo box;Proline-directed 0.00405 2.85166E-16 165.13 _PAASpSPETPSAGQQEAK_ PAAS(0.002)S(0.998)PETPSAGQQEAK PAAS(-27.96)S(27.96)PET(-62.5)PS(-70.02)AGQQEAK 5 2 868.38036 -0.064901 580010 4.5806 177930 0 0 402070 0 0 0 2380 1645 426 426 4404 5010 41949 25862 Mix4_TiO2_1_5 2028 41951 25866 Mix4_TiO2_Reinj_1_5 2543 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.602435 1.8058 0.602435 1.8058 6.75721E-13 149 0.128293 -8.32167 2.85166E-16 165.13 1 S SSPETPSAGQQEA 2.85166E-16 165.13 _PAASSPETPpSAGQQEAK_ PAASSPET(0.397)PS(0.602)AGQQEAK PAAS(-63.47)S(-39.31)PET(-1.81)PS(1.81)AGQQEAK 10 2 868.38036 0.15502 424040 3.3489 424040 0 0 0 0 0 0 2381 1645 72 72 4923;4924 5597;5598 47248 28855 Mix4_TiO2_Reinj_1_5 3651 47248 28855 Mix4_TiO2_Reinj_1_5 3651 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.996048 24.0145 0.105272 -9.2938 0.202205 36.081 0.996048 24.0145 0.0451718 47.6 0.973718 15.6877 0.213149 35.556 0.670588 3.08716 1.11469 3.0872 1 S RKKRRISYVQDEN CAMK2;PKA 0.003024 0.0451718 47.6 _RIpSYVQDENR_ RIS(0.996)Y(0.004)VQDENR RIS(24.01)Y(-24.01)VQDENR 3 2 680.30627 0.28582 2384200 0 0 0 2057000 0 170440 156710 2382 1645 480 480 5405;6158 6151;6152;7030 52675 32198 Mix4_InSol_TiO2_2 1273 52679 32207 Mix4_TiO2_Reinj_1_5 1663 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.84767 7.4796 0.113981 -8.64973 0.0038235 110.19 0.499773 0 0.117988 36.582 0.328007 -3.16268 0.00198172 95.803 0.84767 7.4796 0.00159156 95.308 0.437847 0 0.00124834 88.808 1 S PRSKTPSSPCPAS CK1 0.143 9.28214E-06 143.96 _SKTPpSSPCPASK_ SKTPS(0.848)S(0.151)PCPASK S(-34.6)KT(-34.6)PS(7.48)S(-7.48)PCPAS(-34.6)K 5 2 663.79161 0.74577 28085 0 0 0 0 0 28085 0 2383 1645 481 481 5405;6158 6151;6152;7030 60986 36963 Mix4_TiO2_Reinj_1_5 1647 52679 32207 Mix4_TiO2_Reinj_1_5 1663 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.999935 41.9001 0.999859 38.4953 0.0038235 110.19 0.499773 0 0.117988 36.582 0.999935 41.9001 9.28214E-06 143.96 0.999549 33.4544 0.00159156 95.308 0.998835 29.3334 0.00124834 88.808 1 S RSKTPSSPCPASK ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 9.28214E-06 143.96 _TPSpSPCPASK_ TPSS(1)PCPASK T(-80.11)PS(-41.9)S(41.9)PCPAS(-86.44)K 4 2 556.22811 0.074358 4595100 505200 0 0 2663400 0 682900 743670 2384 1645 446 446 5939 6772 58522 35484 Mix4_InSol_TiO2_1 2543 58522 35484 Mix4_InSol_TiO2_1 2543 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.999996 54.2409 0.999996 54.2409 0.0645043 54.241 0.943837 12.2545 1.03059 12.254 1 S PREPPQSARRKRS 0.0645043 54.241 _TDQADGPREPPQpSARR_ TDQADGPREPPQS(1)ARR T(-54.24)DQADGPREPPQS(54.24)ARR 13 3 620.94979 0.28081 92995 0 0 0 0 0 48346 44649 2385 1645 300 300 5947 6781;6782 58595 35530 Mix4_TiO2_1_5 4090 58599 35535 Mix4_TiO2_Reinj_1_5 4739 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.415202 0 0.415202 0 0.000488299 82.428 0.131776 -6.56962 1.53242 22.288 0.313504 0.335845 0.000280337 89.423 0 0 0.282247 -0.757049 0.00832403 71.891 0.162716 -5.22611 1.69174 17.217 1 S TGSRTDSQSVRHS CAMK2;CK1;PKA/AKT 0.00111111 0.000280337 89.423 _pTDSQSVRHSPIAPSSPSPQVLAQK_ T(0.415)DS(0.415)QS(0.072)VRHS(0.072)PIAPS(0.02)S(0.004)PS(0.001)PQVLAQK T(0)DS(0)QS(-7.58)VRHS(-7.58)PIAPS(-13.13)S(-20.38)PS(-27.88)PQVLAQK 3 4 650.07344 0.1182 0 0 0 0 0 0 0 0 2386 1645 302 302 5947 6781;6782 58589 35523 Mix4_InSol_TiO2_1 5084 58599 35535 Mix4_TiO2_Reinj_1_5 4739 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.335997 0 0.0724489 -7.58228 0.000488299 82.428 0.131776 -6.56962 1.53242 22.288 0.290174 -0.335845 0.000280337 89.423 0 0 0.335997 0 0.00832403 71.891 0.162716 -5.22611 1.69174 17.217 1 S SRTDSQSVRHSPI CK1;GSK3 0.081 0.000280337 89.423 _TDSQpSVRHSPIAPSSPSPQVLAQK_ T(0.046)DS(0.282)QS(0.336)VRHS(0.336)PIAPSSPSPQVLAQK T(-8.66)DS(-0.76)QS(0)VRHS(0)PIAPS(-43.67)S(-43.67)PS(-50.91)PQVLAQK 5 4 650.07344 0.91113 0 0 0 0 0 0 0 0 2387 1645 197 197 6090;6091;6092 6947;6948;6949;6950;6951;6952;6953 60216 36468 Mix4_TiO2_2_2 3883 60216 36468 Mix4_TiO2_2_2 3883 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.859649 8.05158 0.450289 0 0.0209443 65.076 0.859649 8.05158 2.09978E-07 98.942 0.46069 1.78007 1.95833E-07 103.16 0.691536 6.42094 0.597356 48.643 0.000246546 -31.4775 1.29816 31.478 3 S PLPRTLSPTPASA CAMK2;CHK1;CHK1/2;PKA/AKT;PKD;Proline-directed 0.00111111 2.09978E-07 98.942 _TLpSPTPASATAPTSQGIPpTSDEESpTPKK_ T(0.135)LS(0.86)PT(0.005)PASATAPTSQGIPT(0.495)S(0.495)DEES(0.173)T(0.836)PKK T(-8.05)LS(8.05)PT(-22.65)PAS(-43.7)AT(-43.7)APT(-62.32)S(-60.33)QGIPT(0)S(0)DEES(-7.05)T(7.05)PKK 3 3 1013.7677 -0.68294 136160 0 136160 0 0 0 0 0 2388 1645 214 214 6090;6091;6092 6947;6948;6949;6950;6951;6952;6953 60187 36454 Mix4_TiO2_Reinj_1_5 4935 60187 36454 Mix4_TiO2_Reinj_1_5 4935 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.612323 5.05618 0.48253 0 0.0209443 65.076 0.495417 0 2.09978E-07 98.942 0.612323 5.05618 1.95833E-07 103.16 0.24693 0 1.88037 21.485 0.346459 0 1.29816 31.478 2 S SQGIPTSDEESTP CK2;GSK3 0.081 1.95833E-07 103.16 _TLSPTPASATAPTSQGIPpTpSDEESTPK_ TLSPT(0.011)PAS(0.28)AT(0.042)APT(0.033)S(0.033)QGIPT(0.524)S(0.612)DEES(0.232)T(0.232)PK T(-39.51)LS(-31.96)PT(-17.2)PAS(-2.89)AT(-11.15)APT(-12.19)S(-12.19)QGIPT(2.89)S(5.06)DEES(-5.06)T(-5.06)PK 20 3 944.4139 0.19979 1376400 0 0 0 1376400 0 0 0 2389 1645 218 218 6090;6091;6092 6947;6948;6949;6950;6951;6952;6953 60207 36466 Mix4_TiO2_Reinj_1_5 4700 60187 36454 Mix4_TiO2_Reinj_1_5 4935 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.500036 0 0.342318 0 1.86766E-07 101.06 0.17324 -7.05337 2.09978E-07 98.942 0.500036 0 1.95833E-07 103.16 0.24693 0 1.88037 21.485 0.135951 -4.06268 1.29816 31.478 2 S PTSDEESTPKKSK CK1 0.143 1.95833E-07 103.16 _TLSPTPASATAPTSQGIPpTSDEEpSTPKK_ TLSPTPASATAPT(0.001)S(0.001)QGIPT(0.499)S(0.499)DEES(0.5)T(0.5)PKK T(-67.73)LS(-62.13)PT(-45.26)PAS(-41.91)AT(-40.84)APT(-26.46)S(-25.82)QGIPT(0)S(0)DEES(0)T(0)PKK 24 3 987.11222 0.097724 2087900 0 0 0 2087900 0 0 0 2390 1645 893 893 6237 7125;7126 61847 37469 Mix4_TiO2_Reinj_1_5 5867 61847 37469 Mix4_TiO2_Reinj_1_5 5867 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.54166 1.66635 0.508514 1.19521 0.101771 46.428 0.0129939 -18.6899 0.712075 18.69 0.54166 1.66635 9.08862E-05 99.483 0.322898 -1.32135 0.00648481 76.434 0.321713 -1.39569 0.0184845 65.893 2 S RYHKRTSSAVWNS PKA 0.042 9.08862E-05 99.483 _TpSSAVWNpSPPLQGAR_ T(0.369)S(0.542)S(0.089)AVWNS(1)PPLQGAR T(-1.67)S(1.67)S(-7.83)AVWNS(95.41)PPLQGAR 2 2 865.86858 0.15237 171030 0 0 0 171030 0 0 0 2391 1645 894 894 6237 7125;7126 61845 37467 Mix4_InSol_Tio2_Reinj_1 6118 61847 37469 Mix4_TiO2_Reinj_1_5 5867 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.443647 1.39569 0.369961 0 1.16615E-11 157.71 0.0129939 -18.6899 0.712075 18.69 0.0892844 -7.82951 9.08862E-05 99.483 0.437723 1.32135 0.00648481 76.434 0.443647 1.39569 0.0184845 65.893 2 S YHKRTSSAVWNSP CAMK2;PKA 0.003024 9.08862E-05 99.483 _TSpSAVWNpSPPLQGAR_ T(0.235)S(0.322)S(0.444)AVWNS(1)PPLQGAR T(-2.77)S(-1.4)S(1.4)AVWNS(65.89)PPLQGAR 3 2 865.86858 -0.12604 0 0 0 0 0 0 0 0 2392 1645 899 899 6237 7125;7126 61861 37480 Mix4_TiO2_Reinj_1_5 5805 61857 37476 Mix4_TiO2_1_5 4997 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 1 86.4857 1 104.106 1.16615E-11 157.71 0.961018 18.6899 0.712075 18.69 1 86.4857 2.87907E-07 129.59 0.999999 59.856 4.18239E-07 126.01 0.999978 50.958 0.00159001 88.66 1 S SSAVWNSPPLQGA Proline-directed 0.05 1.16615E-11 157.71 _TSSAVWNpSPPLQGAR_ TSSAVWNS(1)PPLQGAR T(-87.63)S(-86.49)S(-94.95)AVWNS(86.49)PPLQGAR 8 2 825.88542 0.23411 1346000 184370 31627 0 672620 0 263950 193470 2393 1645 291 291 6457 7386 65220 39999 Mix4_TiO2_1_6 5563 65221 40000 Mix4_TiO2_Reinj_1_5 7433 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.88031 9.79574 0.88031 9.79574 0.000739364 91.817 0 0 0.69249 3.56623 5.05277E-05 98.439 0.0128531 -15.2484 0.013505 69.678 0.0211139 -15.3502 0.00267325 78.961 1 S ILPDNFSTPTGSR 5.05277E-05 98.439 _VLAPILPDNFpSTPTGSR_ VLAPILPDNFS(0.88)T(0.092)PT(0.014)GS(0.014)R VLAPILPDNFS(9.8)T(-9.8)PT(-18.08)GS(-18.08)R 11 2 932.96387 0.85033 181930 16046 0 0 165890 0 0 0 2394 1645 296 296 6457 7386 65217 39995 Mix4_InSol_TiO2_1 8033 65221 40000 Mix4_TiO2_Reinj_1_5 7433 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.430378 1.29998 0.0137101 -18.076 0.000739364 91.817 0 0 0.268937 -1.9182 5.05277E-05 98.439 0.430378 1.29998 0.013505 69.678 0.139377 -7.15395 0.00267325 78.961 1 S FSTPTGSRTDSQS CK1;CK2;GSK3 0.081 5.05277E-05 98.439 _VLAPILPDNFSTPTGpSR_ VLAPILPDNFS(0.013)T(0.238)PT(0.319)GS(0.43)R VLAPILPDNFS(-15.25)T(-2.58)PT(-1.3)GS(1.3)R 16 2 932.96387 0.11913 0 0 0 0 0 0 0 0 2395 1645 330 330 6799 7779 69003 42316 Mix4_InSol_TiO2_1 5251 69003 42316 Mix4_InSol_TiO2_1 5251 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.999999 65.7854 0.999999 65.7854 0.0141225 65.785 0 0 1 S LVAKQESVVRRAS CHK1;PKD 0.020748 0.0141225 65.785 _YSLVAKQEpSVVR_ YSLVAKQES(1)VVR Y(-65.79)S(-65.79)LVAKQES(65.79)VVR 9 2 729.87125 -0.067378 30773 0 0 0 0 0 30773 0 2396 1646 327 327 453 515 4208 2519 Mix4_TiO2_1_3 5873 4209 2520 Mix4_TiO2_Reinj_1_3 6666 Q9NQU5 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1 0.323337 0 0.323337 0 1.17718E-07 112.4 0.147238 -7.47519 5.30499E-12 129.46 0.127727 -8.15311 3.81861E-07 99.575 0.140415 -6.90334 4.88684E-05 96.098 1 S LTTSDTSSPQKSL CK1 0.081 5.30499E-12 129.46 _AQSLPSDQPVGTFSPLTTSDpTSSPQK_ AQSLPSDQPVGTFSPLT(0.001)T(0.001)S(0.027)DT(0.323)S(0.323)S(0.323)PQK AQS(-81.67)LPS(-81.67)DQPVGT(-52.23)FS(-40.96)PLT(-23.54)T(-24.32)S(-10.73)DT(0)S(0)S(0)PQK 22 2 1378.6368 0.46397 0 0 0 0 0 0 0 0 2397 1646 328 328 453 515 4205 2515 Mix4_InSol_TiO2_1 7024 4209 2520 Mix4_TiO2_Reinj_1_3 6666 Q9NQU5 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1 0.834824 8.15311 0.803637 7.19849 1.17718E-07 112.4 0.823265 7.47519 5.30499E-12 129.46 0.834824 8.15311 3.81861E-07 99.575 0.688255 6.90334 4.88684E-05 96.098 1 S TTSDTSSPQKSLR CDK1;CDK2;CK1;GSK3;Polo box;Proline-directed 0.00405 5.30499E-12 129.46 _AQSLPSDQPVGTFSPLTTSDTSpSPQK_ AQSLPSDQPVGTFSPLTTS(0.017)DT(0.02)S(0.128)S(0.835)PQK AQS(-99.58)LPS(-99.58)DQPVGT(-95.76)FS(-72.54)PLT(-47.02)T(-39.76)S(-16.89)DT(-16.15)S(-8.15)S(8.15)PQK 23 3 919.42693 0.54829 1522400 428490 0 0 834020 0 118080 141800 2398 1646 616 616 3688;3689 4159;4160 34789 21591 Mix4_InSol_Tio2_Reinj_1 3597 34788 21590 Mix4_InSol_TiO2_1 3581 Q9NQU5 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1 1 5.41408 1 30.4342 0.33073 30.434 0 0 1 19.6105 0.564995 19.61 1 42.0098 0.0620542 42.01 1 5.41408 0.674341 5.4141 1 S MKRLRDSPPPKLK NEK6;PKA;Proline-directed 0.042 0.0620542 42.01 _LRDpSPPPKLK_ LRDS(1)PPPKLK LRDS(5.41)PPPKLK 4 2 615.83394 0.78897 408770 42584 0 0 249920 0 61598 54668 2399 1646 560 560 5485 6242 53549 32748 Mix4_TiO2_1_3 7812 53549 32748 Mix4_TiO2_1_3 7812 Q9NQU5;Q9P286 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1;>sp|Q9P286|PAK7_HUMAN Serine/threonine-protein kinase PAK 7 OS=Homo sapiens GN=PAK7 PE=1 SV=1 0.999992 50.958 0.999992 50.958 0.000588497 94.303 0 0 1 S DVPKRKSLVGTPY AURORA;AURORA-1;AURORA-A;CHK1;PKA;PKD 0.006142092 0.000588497 94.303 _pSLVGTPYWMAPEVISR_ S(1)LVGTPYWMAPEVISR S(50.96)LVGT(-50.96)PY(-94.3)WMAPEVIS(-94.3)R 1 2 943.44954 1.5835 35478 35478 0 0 0 0 0 0 2400 1646 346 346 5891 6718;6719 58118 35296 Mix4_TiO2_1_3 3051 58119 35297 Mix4_TiO2_Reinj_1_3 3567 Q9NQU5 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1 0.554582 0.980733 0.554582 0.980733 0.000775084 85.636 0.155874 -7.33667 3.488E-11 136.14 0 0 0 0 2 S GQLPGRSSPAGSP 3.488E-11 136.14 _TAPATGQLPGRpSSPAGpSPR_ TAPAT(0.003)GQLPGRS(0.555)S(0.442)PAGS(1)PR T(-59.18)APAT(-22.75)GQLPGRS(0.98)S(-0.98)PAGS(49.69)PR 12 2 984.44044 0.16145 39818 39818 0 0 0 0 0 0 2401 1646 347 347 5891 6718;6719 58119 35297 Mix4_TiO2_Reinj_1_3 3567 58119 35297 Mix4_TiO2_Reinj_1_3 3567 Q9NQU5 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1 0.844122 7.33667 0.44248 -0.980733 0.000775084 85.636 0.844122 7.33667 3.488E-11 136.14 0 0 0 0 2 S QLPGRSSPAGSPR GSK3;PKA;Polo box;Proline-directed 0.00405 3.488E-11 136.14 _TAPATGQLPGRSpSPAGpSPR_ TAPATGQLPGRS(0.156)S(0.844)PAGS(1)PR T(-70.59)APAT(-46.48)GQLPGRS(-7.34)S(7.34)PAGS(47.36)PR 13 2 984.44044 -0.18132 189430 0 0 0 189430 0 0 0 2402 1647 182 182 74 88 862 571 Mix4_TiO2_Reinj_1_5 5435 862 571 Mix4_TiO2_Reinj_1_5 5435 Q9NQW6;Q9NQW6-2 Q9NQW6 Q9NQW6 >sp|Q9NQW6|ANLN_HUMAN Actin-binding protein anillin OS=Homo sapiens GN=ANLN PE=1 SV=2;>sp|Q9NQW6-2|ANLN_HUMAN Isoform 2 of Actin-binding protein anillin OS=Homo sapiens GN=ANLN 0.999849 38.2256 0.975805 16.7884 0.708427 27.16 0.999849 38.2256 0.00329974 77.383 1 S SEEKAASPPRPLL CDK1;CDK2;Proline-directed 0.0057 0.00329974 77.383 _AApSPPRPLLSNASATPVGR_ AAS(1)PPRPLLSNASATPVGR AAS(38.23)PPRPLLS(-38.23)NAS(-74.65)AT(-77.38)PVGR 3 3 648.00172 -0.16618 246880 57724 0 0 189160 0 0 0 2403 1647 323 323 6139 7007 60594 36627 Mix4_TiO2_Reinj_1_5 4449 60594 36627 Mix4_TiO2_Reinj_1_5 4449 Q9NQW6;Q9NQW6-2 Q9NQW6 Q9NQW6 >sp|Q9NQW6|ANLN_HUMAN Actin-binding protein anillin OS=Homo sapiens GN=ANLN PE=1 SV=2;>sp|Q9NQW6-2|ANLN_HUMAN Isoform 2 of Actin-binding protein anillin OS=Homo sapiens GN=ANLN 1 63.0235 0.999971 45.442 0.153481 45.442 1 63.0235 0.0692727 63.024 1 S LPKTPISPLKTGV CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0692727 63.024 _TPIpSPLK_ TPIS(1)PLK T(-63.02)PIS(63.02)PLK 4 2 418.21989 0.12088 93200 14777 0 0 78423 0 0 0 2404 1648 452 452 3380 3821 31851 19721 Mix4_TiO2_1_1 3846 31851 19721 Mix4_TiO2_1_1 3846 Q9NR09 Q9NR09 Q9NR09 >sp|Q9NR09|BIRC6_HUMAN Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens GN=BIRC6 PE=1 SV=1 0.822015 6.92524 0.822015 6.92524 0.0184316 62.304 0 0 0 0 0 0 1 S DDLLEDSDSEEHS CK2;NEK6 0.076 0.0184316 62.304 _LEGDSDDLLEDpSDSEEHSR_ LEGDS(0.011)DDLLEDS(0.822)DS(0.167)EEHSR LEGDS(-18.85)DDLLEDS(6.93)DS(-6.93)EEHS(-33.13)R 12 3 743.28853 0.30778 110730 110730 0 0 0 0 0 0 2405 1649 30 30 5869 6693 57894 35186 Mix4_TiO2_Reinj_1_3 5294 57894 35186 Mix4_TiO2_Reinj_1_3 5294 Q9NR19 Q9NR19 Q9NR19 >sp|Q9NR19|ACSA_HUMAN Acetyl-coenzyme A synthetase, cytoplasmic OS=Homo sapiens GN=ACSS2 PE=1 SV=1 0.999791 37.054 0.980291 18.5601 0.29283 22.094 0.999791 37.054 0.0400606 49.292 1 S GRARSWSPPPEVS 14-3-3 binding;CAMK2;PKA/AKT;Proline-directed 0.0001701 0.0400606 49.292 _SWpSPPPEVSR_ SWS(1)PPPEVSR S(-37.05)WS(37.05)PPPEVS(-49.29)R 3 2 611.26863 0.27952 161860 37891 0 0 123970 0 0 0 2406 1650 89 89 1499;3001;3082 1683;3412;3503 29331 18299 Mix4_InSol_TiO2_1 2698 29331 18299 Mix4_InSol_TiO2_1 2698 Q9NR30;Q9NR30-2 Q9NR30 Q9NR30 >sp|Q9NR30|DDX21_HUMAN Nucleolar RNA helicase 2 OS=Homo sapiens GN=DDX21 PE=1 SV=5;>sp|Q9NR30-2|DDX21_HUMAN Isoform 2 of Nucleolar RNA helicase 2 OS=Homo sapiens GN=DDX21 0.999996 54.4128 0.999946 42.6964 0.0855087 42.696 0.999995 53.3777 0.0127336 70.011 0.999996 54.4128 0.000173031 113.9 0.99994 42.2166 0.0725921 46.206 1 S PSQNDISPKTKSL CDK1;Proline-directed 0.0057 0.000173031 113.9 _KKEEPSQNDIpSPK_ KKEEPSQNDIS(1)PK KKEEPS(-54.41)QNDIS(54.41)PK 11 2 790.37181 0.34934 2086800 54400 0 0 1691700 0 186660 154040 2407 1650 121 121 3992;6635 4548;7596 37788 23196 Mix4_TiO2_Reinj_1_5 3806 37788 23196 Mix4_TiO2_Reinj_1_5 3806 Q9NR30;Q9NR30-2 Q9NR30 Q9NR30 >sp|Q9NR30|DDX21_HUMAN Nucleolar RNA helicase 2 OS=Homo sapiens GN=DDX21 PE=1 SV=5;>sp|Q9NR30-2|DDX21_HUMAN Isoform 2 of Nucleolar RNA helicase 2 OS=Homo sapiens GN=DDX21 1 188.857 1 39.6654 8.58141E-12 162.52 1 188.857 1.98603E-16 188.86 1 128.04 3.44407E-07 128.04 1 70.8701 0.0128059 70.87 1 S TKNEEPSEEEIDA CK2 0.117 1.98603E-16 188.86 _NEEPpSEEEIDAPKPK_ NEEPS(1)EEEIDAPKPK NEEPS(188.86)EEEIDAPKPK 5 2 896.38785 -0.79515 1174800 541480 0 0 482390 0 71328 79588 2408 1651 564 564 409 467 3890 2326 Mix4_TiO2_1_5 6243 3891 2327 Mix4_TiO2_Reinj_1_5 7145 Q9NRA8;Q9NRA8-2 Q9NRA8 Q9NRA8 >sp|Q9NRA8|4ET_HUMAN Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens GN=EIF4ENIF1 PE=1 SV=2;>sp|Q9NRA8-2|4ET_HUMAN Isoform 2 of Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens GN=EIF4ENIF1 1 68.7736 1 68.7736 0.00184933 93.01 0.999994 51.972 0.000221152 112.24 1 S LGQRAPSPPLSQV CAMK2;GSK3;Proline-directed 0.042 0.000221152 112.24 _APpSPPLSQVFQTR_ APS(1)PPLSQVFQTR APS(68.77)PPLS(-68.77)QVFQT(-93.01)R 3 2 754.36887 -0.10312 211940 49737 0 0 162200 0 0 0 2409 1651 951 951 5749 6552 56524 34515 Mix4_TiO2_Reinj_1_5 3302 56523 34514 Mix4_InSol_TiO2_1 3486 Q9NRA8;Q9NRA8-2 Q9NRA8 Q9NRA8 >sp|Q9NRA8|4ET_HUMAN Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens GN=EIF4ENIF1 PE=1 SV=2;>sp|Q9NRA8-2|4ET_HUMAN Isoform 2 of Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens GN=EIF4ENIF1 0.982187 17.8128 0 0 0.982187 17.8128 0.169108 33.83 0.721816 7.15125 0.0691758 40.981 0 0 1 S PSQRSSSPVGLAK CAMK2;Polo box;Proline-directed 0.00405 0.0691758 40.981 _SSpSPVGLAK_ S(0.002)S(0.016)S(0.982)PVGLAK S(-27.99)S(-17.81)S(17.81)PVGLAK 3 2 463.22316 -0.017696 122440 0 0 0 85681 0 36757 0 2410 1652 284 284 2592 2947 24237 15039 Mix4_TiO2_Reinj_1_2 2029 24237 15039 Mix4_TiO2_Reinj_1_2 2029 Q9NRD1 Q9NRD1 Q9NRD1 >sp|Q9NRD1|FBX6_HUMAN F-box only protein 6 OS=Homo sapiens GN=FBXO6 PE=1 SV=1 0.999322 31.6873 0.999322 31.6873 0.00986771 73.471 0 0 0 0 1 S QEEAAQSPYRAVV CDK1;CDK2;Proline-directed 0.0057 0.00986771 73.471 _HGQEEAAQpSPYR_ HGQEEAAQS(0.999)PY(0.001)R HGQEEAAQS(31.69)PY(-31.69)R 9 2 726.79881 0.27091 89118 0 0 0 89118 0 0 0 2411 1654 541 541 426 488 4058 2429 Mix4_TiO2_Reinj_1_4 8737 4058 2429 Mix4_TiO2_Reinj_1_4 8737 Q9NRG9 Q9NRG9 Q9NRG9 >sp|Q9NRG9|AAAS_HUMAN Aladin OS=Homo sapiens GN=AAAS PE=1 SV=1 0.784375 6.33229 0.784375 6.33229 0.111784 76.579 1 S PPVLPHSPHSHL_ ERK/MAPK;NEK6;Proline-directed;WW GroupIV 0.0023175 0.111784 76.579 _AQEPPAGGGGSIHDLPLFTETSPTSAPWDPLPGPPPVLPHpSPHSHL_ AQEPPAGGGGSIHDLPLFTET(0.004)S(0.004)PT(0.012)S(0.012)APWDPLPGPPPVLPHS(0.784)PHS(0.183)HL AQEPPAGGGGS(-35.46)IHDLPLFT(-32.39)ET(-23.24)S(-23.24)PT(-17.98)S(-17.98)APWDPLPGPPPVLPHS(6.33)PHS(-6.33)HL 41 4 1194.5787 -0.30794 668060 0 0 0 668060 0 0 0 2412 1655 276 276 3445 3890 32491 20148 Mix4_TiO2_1_3 8026 32491 20148 Mix4_TiO2_1_3 8026 Q9NRL3 Q9NRL3 Q9NRL3 >sp|Q9NRL3|STRN4_HUMAN Striatin-4 OS=Homo sapiens GN=STRN4 PE=1 SV=2 1 70.3851 1 70.3851 8.44742E-13 128.84 0 0 1 S NCEDEDSDEDDEL CK2 0.117 8.44742E-13 128.84 _LGGSVLGQIPFLQNCEDEDpSDEDDELDSVQHK_ LGGSVLGQIPFLQNCEDEDS(1)DEDDELDSVQHK LGGS(-91.49)VLGQIPFLQNCEDEDS(70.39)DEDDELDS(-70.39)VQHK 20 3 1223.5242 0.95542 61244 61244 0 0 0 0 0 0 2413 1656 576 576 4582 5203 43333 26564 Mix4_InSol_TiO2_1 4272 43337 26569 Mix4_TiO2_Reinj_1_5 4001 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.998843 29.3622 0.982581 17.5134 0.0039526 123.16 0.882226 8.74531 0.0351459 50.919 0.916478 10.4032 0.00239749 129.27 0 0 0.998843 29.3622 0.0014611 92.837 0.902554 9.66708 0.00282545 73.142 1 S KKQIQTSPVPVRK Proline-directed 0.05 0.00239749 129.27 _QIQTpSPVPVR_ QIQT(0.001)S(0.999)PVPVR QIQT(-29.36)S(29.36)PVPVR 5 2 602.80792 0.23374 1457300 285560 22455 0 936500 0 120070 92670 2414 1656 380 380 4841 5501 46279 28306 Mix4_TiO2_Reinj_1_5 4170 46278 28303 Mix4_TiO2_Reinj_1_5 4157 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 1 58.4879 1 51.4666 0.0606942 51.467 0 0 1 58.4879 0.00288542 82.734 0 0 1 59.5527 0.0266528 59.553 1 32.7992 0.267718 32.799 1 S TLARRDSLQKPGL AURORA;AURORA-1;AURORA-A;CAMK2;CHK1;CHK1/2;PKA;PKD 0.003192 0.00288542 82.734 _RDpSLQKPGLEAPPR_ RDS(1)LQKPGLEAPPR RDS(58.49)LQKPGLEAPPR 3 2 822.41689 -0.049681 3207200 275130 0 0 2541500 0 231630 158980 2415 1656 526 526 5400 6146 52602 32161 Mix4_TiO2_1_5 6943 52603 32162 Mix4_TiO2_Reinj_1_5 7735 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.820531 7.52044 0.820531 7.52044 0.317403 38.021 0.0747334 -10.4678 0.000678862 80.169 1 S KHLLLRSKSEQYD CK2;NEK6 0.076 0.000678862 80.169 _pSKSEQYDLDSLCAGMEQSLR_ S(0.821)KS(0.145)EQY(0.028)DLDS(0.006)LCAGMEQSLR S(7.52)KS(-7.52)EQY(-14.71)DLDS(-21.11)LCAGMEQS(-38.02)LR 1 3 799.67479 -0.48829 29863 29863 0 0 0 0 0 0 2416 1656 535 535 5400 6146 52603 32162 Mix4_TiO2_Reinj_1_5 7735 52603 32162 Mix4_TiO2_Reinj_1_5 7735 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.832332 10.4678 0.00635735 -21.1082 0.317403 38.021 0.832332 10.4678 0.000678862 80.169 1 S EQYDLDSLCAGME 0.000678862 80.169 _SKSEQYDLDpSLCAGMEQSLR_ S(0.075)KS(0.075)EQY(0.018)DLDS(0.832)LCAGMEQSLR S(-10.47)KS(-10.47)EQY(-16.6)DLDS(10.47)LCAGMEQS(-80.17)LR 10 3 799.67479 0.38983 101110 0 0 0 101110 0 0 0 2417 1656 277 277 5579 6358 54592 33421 Mix4_TiO2_Reinj_1_5 5310 54592 33421 Mix4_TiO2_Reinj_1_5 5310 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.717034 4.03859 0 0 0.717034 4.03859 1.49063E-11 133.74 1 S RSPSFQSKTPPET CK1 0.081 1.49063E-11 133.74 _SPSFQpSKTPPETGGYASLPTK_ SPSFQS(0.717)KT(0.283)PPETGGYASLPTK S(-53.31)PS(-52.38)FQS(4.04)KT(-4.04)PPET(-45)GGY(-52.01)AS(-73.8)LPT(-81.73)K 6 3 754.02262 0.49451 242780 0 0 0 242780 0 0 0 2418 1656 342 342 5657 6443 55222 33782 Mix4_TiO2_1_5 5854 55222 33782 Mix4_TiO2_1_5 5854 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.991194 20.5202 0.991194 20.5202 8.62727E-26 183.04 0 0 1 S QVFASDSPPQSLL GSK3;Proline-directed 0.05 8.62727E-26 183.04 _SQVFASDpSPPQSLLTPSR_ SQVFAS(0.009)DS(0.991)PPQSLLTPSR S(-85.09)QVFAS(-20.52)DS(20.52)PPQS(-48.85)LLT(-97.26)PS(-130.1)R 8 2 998.97242 1.0777 110790 110790 0 0 0 0 0 0 2419 1656 408 408 6119 6984 60459 36558 Mix4_TiO2_Reinj_1_5 2609 60459 36558 Mix4_TiO2_Reinj_1_5 2609 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.996248 24.7867 0.680766 6.2992 0.653857 6.2992 0.996248 24.7867 0.0484112 46.527 1 S VPSRTNSFNSHQP CAMK2;CK1 0.042 0.0484112 46.527 _TNpSFNSHQPR_ T(0.003)NS(0.996)FNSHQPR T(-24.79)NS(24.79)FNS(-33.52)HQPR 3 2 634.26441 0.36783 342200 43937 0 0 298270 0 0 0 2420 1658 361 361 5167 5882 50080 30614 Mix4_TiO2_Reinj_1_5 3128 50076 30610 Mix4_InSol_Tio2_Reinj_1 3312 Q9NRX5 Q9NRX5 Q9NRX5 >sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 OS=Homo sapiens GN=SERINC1 PE=1 SV=1 0.888472 9.01259 0.445011 -0.959129 0.305819 27.619 0.888472 9.01259 0.0672275 47.664 0.5 0 0.00301465 87.554 0.228668 -5.28037 0.00157408 94.299 1 S EDGGARSDGSLED 0.00157408 94.299 _pSDGSLEDGDDVHR_ S(0.888)DGS(0.112)LEDGDDVHR S(9.01)DGS(-9.01)LEDGDDVHR 1 2 741.28065 0.25733 478360 0 0 0 367890 0 110470 0 2421 1658 364 364 5167 5882 50076 30610 Mix4_InSol_Tio2_Reinj_1 3312 50076 30610 Mix4_InSol_Tio2_Reinj_1 3312 Q9NRX5 Q9NRX5 Q9NRX5 >sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 OS=Homo sapiens GN=SERINC1 PE=1 SV=1 0.771332 5.28037 0.554989 0.959129 0.305819 27.619 0.160576 -7.18301 0.0672275 47.664 0.5 0 0.00301465 87.554 0.771332 5.28037 0.00157408 94.299 1 S GARSDGSLEDGDD CK1;CK2;PLK;PLK1 0.0027378 0.00157408 94.299 _SDGpSLEDGDDVHR_ S(0.229)DGS(0.771)LEDGDDVHR S(-5.28)DGS(5.28)LEDGDDVHR 4 2 741.28065 0.39719 276020 27026 0 0 0 0 110470 138520 2422 1661 15 15 20 28 241 142 Mix4_TiO2_Reinj_1_6 6225 241 142 Mix4_TiO2_Reinj_1_6 6225 Q9NS69 Q9NS69 Q9NS69 >sp|Q9NS69|TOM22_HUMAN Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens GN=TOMM22 PE=1 SV=3 1 195.532 1 57.0904 8.98218E-24 164.41 0 0 1 195.532 1.4862E-38 195.53 0 0 1 66.197 0.0119231 66.197 1 S GAGEPQSPDELLP CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.4862E-38 195.53 _(ac)AAAVAAAGAGEPQpSPDELLPK_ AAAVAAAGAGEPQS(1)PDELLPK AAAVAAAGAGEPQS(195.53)PDELLPK 14 2 1042.9986 0.43029 760720 155210 0 0 572960 0 0 32552 2423 1663 685 685 525;4359;4360 594;4958;4959 4914 2969 Mix4_TiO2_Reinj_1_5 6923 41349 25432 Mix4_TiO2_Reinj_1_1 6693 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.869119 10.383 0.179138 -3.54719 0.00505022 77.891 0.349483 0.338497 1.01312 41.787 0.869119 10.383 1.20523E-12 123.3 0.142411 -4.60858 1.90358 15.534 1 S GSVPFISHSGSPE GSK3 0.081 1.20523E-12 123.3 _ASSDKNVDSLSAPHNHPPEDPFGSVPFIpSHSGSPEK_ ASSDKNVDSLS(0.001)APHNHPPEDPFGS(0.08)VPFIS(0.869)HS(0.026)GS(0.024)PEK AS(-41.24)S(-41.24)DKNVDS(-34.38)LS(-30.81)APHNHPPEDPFGS(-10.38)VPFIS(10.38)HS(-15.21)GS(-15.6)PEK 29 4 963.43907 -0.46107 2039400 0 0 0 2039400 0 0 0 2424 1663 687 687 525;4359;4360 594;4958;4959 41349 25432 Mix4_TiO2_Reinj_1_1 6693 41349 25432 Mix4_TiO2_Reinj_1_1 6693 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.493309 0 0.405421 0 0.00505022 77.891 0.323278 -0.338497 1.01312 41.787 0.493309 0 1.20523E-12 123.3 0.411531 0 1.90358 15.534 1 S VPFISHSGSPEKK 1.20523E-12 123.3 _NVDSLSAPHNHPPEDPFGSVPFISHpSGSPEK_ NVDSLSAPHNHPPEDPFGSVPFIS(0.013)HS(0.493)GS(0.493)PEK NVDS(-121.78)LS(-114.6)APHNHPPEDPFGS(-60.67)VPFIS(-15.67)HS(0)GS(0)PEK 26 3 1121.5086 0.50852 0 0 0 0 0 0 0 0 2425 1663 689 689 525;4359;4360 594;4958;4959 41345 25427 Mix4_TiO2_1_6 5432 41349 25432 Mix4_TiO2_Reinj_1_1 6693 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.774291 6.3881 0.774291 6.3881 0.00505022 77.891 0.323278 -0.338497 1.01312 41.787 0.684149 4.36755 1.20523E-12 123.3 0.411531 0 1.90358 15.534 1 S FISHSGSPEKKAE CDK1;CDK2;CK1;Proline-directed 0.0057 1.20523E-12 123.3 _NVDSLSAPHNHPPEDPFGSVPFISHSGpSPEK_ NVDSLSAPHNHPPEDPFGS(0.001)VPFIS(0.047)HS(0.178)GS(0.774)PEK NVDS(-54.55)LS(-54.46)APHNHPPEDPFGS(-30.94)VPFIS(-12.15)HS(-6.39)GS(6.39)PEK 28 4 841.3833 0.096084 1301300 190780 0 0 1110600 0 0 0 2426 1663 824 824 1173;5324 1318;6060 51676 31639 Mix4_TiO2_1_5 8488 51673 31635 Mix4_TiO2_1_3 8793 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.45504 0 0.45504 0 3.56751E-26 162.1 0.446658 0 3.06584E-12 123.45 0.329004 0 2.05497E-18 143.46 0.307995 0 2.01161E-12 128.24 1 S SVYRDRSGSGPTQ CAMK2;CHK1;PKD 0.020748 3.56751E-26 162.1 _pSGSGPTQDLNTILLTSAQLSSDVAVETPK_ S(0.455)GS(0.455)GPT(0.087)QDLNT(0.003)ILLTSAQLSSDVAVETPK S(0)GS(0)GPT(-7.21)QDLNT(-21.33)ILLT(-53.96)S(-77.32)AQLS(-109.93)S(-119.66)DVAVET(-135.45)PK 1 3 1003.827 -0.19412 0 0 0 0 0 0 0 0 2427 1663 826 826 1173;5324 1318;6060 51679 31644 Mix4_TiO2_1_6 7051 51673 31635 Mix4_TiO2_1_3 8793 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.805152 8.81295 0.805152 8.81295 3.56751E-26 162.1 0.701538 6.36846 3.06584E-12 123.45 0.755695 7.57135 2.05497E-18 143.46 0.347163 0 2.01161E-12 128.24 1 S YRDRSGSGPTQDL 14-3-3 binding;CAMK2;PKA/AKT 0.0001701 3.56751E-26 162.1 _SGpSGPTQDLNTILLTSAQLSSDVAVETPK_ S(0.089)GS(0.805)GPT(0.106)QDLNTILLTSAQLSSDVAVETPK S(-9.56)GS(8.81)GPT(-8.81)QDLNT(-57.3)ILLT(-92.98)S(-92.59)AQLS(-118.31)S(-128.36)DVAVET(-132.28)PK 3 2 1505.2368 0.72575 4291300 149640 76988 0 4064700 0 0 0 2428 1663 839 839 1173;5324 1318;6060 10974 6727 Mix4_TiO2_1_5 8405 51673 31635 Mix4_TiO2_1_3 8793 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.185566 0 0.185566 0 3.56751E-26 162.1 0.00297344 -19.1761 3.06584E-12 123.45 2.82281E-06 -50.6652 2.05497E-18 143.46 0.000424953 -28.0756 2.01161E-12 128.24 1 S NTILLTSAQLSSD GSK3;NEK6 0.076 3.56751E-26 162.1 _DRSGSGPTQDLNTILLpTSAQLSSDVAVETPK_ DRS(0.157)GS(0.157)GPT(0.157)QDLNT(0.157)ILLT(0.186)S(0.186)AQLS(0.002)SDVAVETPK DRS(-0.74)GS(-0.74)GPT(-0.74)QDLNT(-0.74)ILLT(0)S(0)AQLS(-20.06)S(-26)DVAVET(-44.29)PK 18 3 1094.203 0.27239 0 0 0 0 0 0 0 0 2429 1663 742 742 2330 2638 21586 13219 Mix4_TiO2_Reinj_1_5 4252 21586 13219 Mix4_TiO2_Reinj_1_5 4252 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.99857 28.4415 0.736544 4.46491 4.27107E-13 151.84 0.99857 28.4415 8.7571E-22 194.82 1 S GNDESESDFESDP CK2;GSK3 0.081 8.7571E-22 194.82 _GNDESEpSDFESDPPSPK_ GNDES(0.001)ES(0.999)DFESDPPSPK GNDES(-28.44)ES(28.44)DFES(-78.56)DPPS(-139.58)PK 7 2 958.85711 0.35384 572420 9.5616 174860 0 0 397570 0 0 0 2430 1663 728 728 3246 3680 30703 19065 Mix4_TiO2_Reinj_1_5 1926 30703 19065 Mix4_TiO2_Reinj_1_5 1926 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.999826 37.5978 0 0 0.999826 37.5978 0.000833441 80.949 0.984027 17.8963 0.203141 29.526 0.5 0 0.432853 15.843 1 S RTGKKTSVQGQVQ AURORA;AURORA-1;AURORA-A 0.006142092 0.000833441 80.949 _KTpSVQGQVQK_ KTS(1)VQGQVQK KT(-37.6)S(37.6)VQGQVQK 3 2 591.79755 0.16764 174750 0 0 0 153630 0 11010 10113 2431 1663 1029 1029 4846 5508;5509 46431 28452 Mix4_TiO2_1_5 5011 46431 28452 Mix4_TiO2_1_5 5011 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.999859 38.6143 0.999859 38.6143 1.27491E-25 196.49 0 0 0.989123 20.3695 7.01589E-09 128.07 1 S KVGRRDSQSSNEF CAMK2;CHK1;PKA;PKA/AKT;PKD 0.00111111 1.27491E-25 196.49 _RDpSQSSNEFLTISDSK_ RDS(1)QSSNEFLTISDSK RDS(38.61)QS(-38.61)S(-54.1)NEFLT(-113.27)IS(-119.26)DS(-170.05)K 3 2 947.41493 0.64503 2271700 484360 0 0 1787300 0 0 0 2432 1663 1031 1031 4846 5508;5509 46444 28458 Mix4_TiO2_1_1 4803 46445 28459 Mix4_TiO2_1_5 5166 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.683977 2.83558 0.683977 2.83558 3.33908E-09 132.97 0 0 0.0788451 -8.88292 7.01589E-09 128.07 2 S GRRDSQSSNEFLT CK2 0.117 3.33908E-09 132.97 _RDSQpSpSNEFLTISDSK_ RDS(0.393)QS(0.684)S(0.922)NEFLTISDSK RDS(-2.84)QS(2.84)S(8.95)NEFLT(-34.87)IS(-46.37)DS(-46.37)K 5 2 987.3981 0.54102 138700 138700 0 0 0 0 0 0 2433 1663 1032 1032 4846 5508;5509 46445 28459 Mix4_TiO2_1_5 5166 46445 28459 Mix4_TiO2_1_5 5166 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.984812 18.1186 0.984812 18.1186 3.33908E-09 132.97 0 0 0.971029 15.2504 4.47443E-09 131.44 2 S RRDSQSSNEFLTI CK1 0.081 3.33908E-09 132.97 _RDpSQSpSNEFLTISDSK_ RDS(1)QS(0.015)S(0.985)NEFLTISDSK RDS(56.27)QS(-18.12)S(18.12)NEFLT(-80.92)IS(-101.47)DS(-119.57)K 6 2 987.3981 0.43216 958200 361270 0 0 596940 0 0 0 2434 1663 10 10 5215 5936 50501 30953 Mix4_InSol_Tio2_Reinj_1 3521 50511 30965 Mix4_TiO2_1_5 2811 Q9NSY1;Q9NSY1-2;Q9NSY1-3 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2;>sp|Q9NSY1-2|BMP2K_HUMAN Isoform 2 of BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K;>sp|Q9NSY1-3|BMP2K_HUMAN Isoform 3 of BMP-2-inducible protein kinase OS=H 0.922392 10.7501 0.896212 9.36263 4.51856E-29 175.75 0 0 0.889197 9.04446 2.96948E-19 147.46 0 0 0.83652 7.09016 3.39785E-13 134.34 0.922392 10.7501 7.88506E-13 130.3 1 S FSRMPKSEGGSGG GSK3 0.081 4.51856E-29 175.75 _pSEGGSGGGAAGGGAGGAGAGAGCGSGGSSVGVR_ S(0.922)EGGS(0.078)GGGAAGGGAGGAGAGAGCGSGGSSVGVR S(10.75)EGGS(-10.75)GGGAAGGGAGGAGAGAGCGS(-126.27)GGS(-130.3)S(-130.3)VGVR 1 3 858.35254 -0.25454 3641000 3.2977 546790 0 0 1409900 0 925890 758420 2435 1663 14 14 5215 5936 50507 30959 Mix4_TiO2_1_3 2752 50511 30965 Mix4_TiO2_1_5 2811 Q9NSY1;Q9NSY1-2;Q9NSY1-3 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2;>sp|Q9NSY1-2|BMP2K_HUMAN Isoform 2 of BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K;>sp|Q9NSY1-3|BMP2K_HUMAN Isoform 3 of BMP-2-inducible protein kinase OS=H 0.880343 8.66713 0.880343 8.66713 4.51856E-29 175.75 0 0 0.880231 8.66253 2.96948E-19 147.46 0 0 0.527036 0.47022 3.39785E-13 134.34 0.53819 0.664716 7.88506E-13 130.3 1 S PKSEGGSGGGAAG CK1 0.143 4.51856E-29 175.75 _SEGGpSGGGAAGGGAGGAGAGAGCGSGGSSVGVR_ S(0.12)EGGS(0.88)GGGAAGGGAGGAGAGAGCGSGGSSVGVR S(-8.67)EGGS(8.67)GGGAAGGGAGGAGAGAGCGS(-100.38)GGS(-100.38)S(-100.38)VGVR 5 2 1287.0252 0.38276 741820 0.67189 177890 0 0 289330 0 21133 253470 2436 1663 947 947 5243 5968 50885 31185 Mix4_TiO2_1_1 7809 50900 31205 Mix4_TiO2_Reinj_1_1 8571 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.791428 5.79156 0.791428 5.79156 5.10125E-18 154.48 0.469735 -0.455615 6.39742E-07 105.56 0.5 0 1.00419E-46 222.82 0.443195 -0.991085 2.20502E-07 113.78 1 S LTSTSKSESNEDL CK1 0.143 1.00419E-46 222.82 _pSESNEDLFGLVPFDEITGSQQQK_ S(0.791)ES(0.209)NEDLFGLVPFDEITGSQQQK S(5.79)ES(-5.79)NEDLFGLVPFDEIT(-132.51)GS(-146.34)QQQK 1 3 883.39697 -0.022238 1143400 0.1502 555220 0 0 588150 0 0 0 2437 1663 949 949 5243 5968 50900 31205 Mix4_TiO2_Reinj_1_1 8571 50900 31205 Mix4_TiO2_Reinj_1_1 8571 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.59498 1.67026 0.579644 1.39545 5.10125E-18 154.48 0.55931 1.03519 6.39742E-07 105.56 0.59498 1.67026 1.00419E-46 222.82 0.562044 1.08339 2.20502E-07 113.78 1 S STSKSESNEDLFG CK1;CK2 0.117 1.00419E-46 222.82 _SEpSNEDLFGLVPFDEITGSQQQK_ S(0.405)ES(0.595)NEDLFGLVPFDEITGSQQQK S(-1.67)ES(1.67)NEDLFGLVPFDEIT(-212.87)GS(-222.82)QQQK 3 3 883.39697 -0.27519 48301000 6.3453 5889600 185670 0 42071000 154790 0 0 2438 1664 1358 1358 188;189;449 217;218;219;511 1949 1301 Mix4_InSol_Tio2_Reinj_1 4129 1952 1304 Mix4_TiO2_1_5 3277 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 1 81.5432 1 66.8118 9.03743E-48 241.63 0 0 0.999997 55.6396 3.24724E-39 230.48 0.999997 55.5647 2.83495E-21 169.88 1 81.5432 3.30715E-31 198 1 S AQQRAESPESSAI CAMK2;GSK3;Proline-directed 0.042 9.03743E-48 241.63 _AEpSPESSAIESTQSTPQK_ AES(1)PESSAIESTQSTPQK AES(81.54)PES(-81.54)S(-98)AIES(-163.63)T(-176.3)QS(-193.9)T(-198)PQK 3 2 978.92533 0.58086 3199400 600170 0 0 2009100 0 390730 199420 2439 1664 1361 1361 188;189;449 217;218;219;511 4185 2497 Mix4_InSol_Tio2_Reinj_1 4049 1952 1304 Mix4_TiO2_1_5 3277 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.517296 1.25608 0.043312 -13.3965 9.03743E-48 241.63 0 0 0.122089 -7.91744 3.24724E-39 230.48 0.333307 0 2.83495E-21 169.88 0.517296 1.25608 3.30715E-31 198 1 S RAESPESSAIEST CK1 0.081 9.03743E-48 241.63 _AQQRAESPEpSSAIESTQSTPQK_ AQQRAES(0.387)PES(0.517)S(0.095)AIESTQSTPQK AQQRAES(-1.26)PES(1.26)S(-7.35)AIES(-37.52)T(-41.18)QS(-41.28)T(-41.28)PQK 10 3 814.03777 -0.15761 69642 0 0 0 0 0 0 69642 2440 1664 1362 1362 188;189;449 217;218;219;511 1948 1300 Mix4_InSol_TiO2_1 4210 1952 1304 Mix4_TiO2_1_5 3277 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.333307 0 0.00980707 -19.8472 9.03743E-48 241.63 0 0 0.122089 -7.91744 3.24724E-39 230.48 0.333307 0 2.83495E-21 169.88 0.162915 -11.3634 0.719382 28.708 1 S AESPESSAIESTQ CK1;CK2;GSK3 0.081 9.03743E-48 241.63 _AEpSPESSAIESTQSTPQK_ AES(0.333)PES(0.333)S(0.333)AIESTQSTPQK AES(0)PES(0)S(0)AIES(-39.35)T(-39.35)QS(-61.02)T(-61.02)PQK 7 3 652.95265 0.21206 0 0 0 0 0 0 0 0 2441 1664 1369 1369 188;189;449 217;218;219;511 1984 1316 Mix4_InSol_Tio2_Reinj_1 3828 1971 1309 Mix4_TiO2_1_5 3107 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.513013 5.59832 0.211662 -5.70739 9.03743E-48 241.63 0 0 0.0222159 -16.4719 3.84787E-11 136.56 0.118292 -8.24837 1.49274E-10 124.41 0.513013 5.59832 0.719382 28.708 2 S AIESTQSTPQKGR CK1 0.081 3.52311E-31 196.92 _AEpSPESSAIESTQpSTPQKGR_ AES(0.587)PES(0.169)S(0.163)AIES(0.165)T(0.165)QS(0.513)T(0.238)PQKGR AES(10.55)PES(-10.55)S(-11.36)AIES(-11.02)T(-11.02)QS(5.6)T(-5.6)PQKGR 14 2 1125.4698 0.67915 328120 0 0 0 0 0 0 328120 2442 1664 1406 1406 1696 1906 15501 9351 Mix4_TiO2_1_5 6844 15501 9351 Mix4_TiO2_1_5 6844 Q9NTI5 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1 0.484554 0 0.484554 0 0.00140559 82.382 0 0 1 S ATKENDSSEEVDV CK2 0.117 0.00140559 82.382 _ENDpSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVR_ ENDS(0.485)S(0.485)EEVDVFQGS(0.025)S(0.006)PVDDIPQEETEEEEVSTVNVR ENDS(0)S(0)EEVDVFQGS(-12.84)S(-19.36)PVDDIPQEET(-37.47)EEEEVS(-53.14)T(-57.22)VNVR 4 3 1368.5798 -0.023562 0 0 0 0 0 0 0 0 2443 1664 1407 1407 1696 1906 15501 9351 Mix4_TiO2_1_5 6844 15501 9351 Mix4_TiO2_1_5 6844 Q9NTI5 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1 0.484554 0 0.484554 0 0.00140559 82.382 0 0 1 S TKENDSSEEVDVF 0.00140559 82.382 _ENDpSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVR_ ENDS(0.485)S(0.485)EEVDVFQGS(0.025)S(0.006)PVDDIPQEETEEEEVSTVNVR ENDS(0)S(0)EEVDVFQGS(-12.84)S(-19.36)PVDDIPQEET(-37.47)EEEEVS(-53.14)T(-57.22)VNVR 5 3 1368.5798 -0.023562 0 0 0 0 0 0 0 0 2444 1664 1257 1257 2260;2261 2556;2558 20865 12806 Mix4_TiO2_Reinj_1_5 4116 20865 12806 Mix4_TiO2_Reinj_1_5 4116 Q9NTI5;Q9NTI5-2;Q9NTI5-5 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B;>sp|Q9NTI5-5|PDS5B_HUMAN Isoform 5 of 0.999421 32.5837 0.893569 9.24192 5.9399E-26 206.11 0.96516 14.5368 0.147738 41.428 0.999421 32.5837 3.52517E-33 215.26 0.826687 7.6374 0.618292 24.56 0 0 1 S KRGHTASESDEQQ CK2 0.117 3.52517E-33 215.26 _GHTApSESDEQQWPEEK_ GHTAS(0.999)ES(0.001)DEQQWPEEK GHT(-45.55)AS(32.58)ES(-32.58)DEQQWPEEK 5 2 969.38109 0.084075 1111100 54.997 212870 15311 0 862680 0 20220 0 2445 1664 1259 1259 2260;2261 2556;2558 20866 12807 Mix4_TiO2_Reinj_1_5 4146 20865 12806 Mix4_TiO2_Reinj_1_5 4116 Q9NTI5;Q9NTI5-2;Q9NTI5-5 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B;>sp|Q9NTI5-5|PDS5B_HUMAN Isoform 5 of 0.816463 9.49243 0.328882 -0.172841 5.9399E-26 206.11 0.0339559 -14.5368 0.147738 41.428 0.816463 9.49243 3.52517E-33 215.26 0.0308836 -14.2761 0.618292 24.56 0 0 1 S GHTASESDEQQWP CK1 0.143 3.52517E-33 215.26 _GHTASEpSDEQQWPEEK_ GHT(0.092)AS(0.092)ES(0.816)DEQQWPEEK GHT(-9.49)AS(-9.49)ES(9.49)DEQQWPEEK 7 3 646.58982 0.21892 233890 11.577 0 0 0 233890 0 0 0 2446 1664 1379 1379 2417 2739;2740 22601 14095 Mix4_InSol_TiO2_1 2189 22601 14095 Mix4_InSol_TiO2_1 2189 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.61902 4.34513 0.465289 -0.597668 0.00867864 74.828 0.61902 4.34513 0.0246995 59.22 0.235264 -4.13142 0.0514485 51.951 1 S KGRGRPSKTPSPS GSK3;PKA 0.042 0.0246995 59.22 _GRPpSKTPSPSQPK_ GRPS(0.619)KT(0.228)PS(0.121)PS(0.032)QPK GRPS(4.35)KT(-4.35)PS(-7.09)PS(-12.82)QPK 4 2 723.85867 2.1375 124570 0 0 0 0 0 124570 0 2447 1664 1383 1383 2417;6157 2739;2740;7029 60974 36938 Mix4_TiO2_Reinj_1_5 1818 60974 36938 Mix4_TiO2_Reinj_1_5 1818 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.988553 19.3648 0.985693 18.3872 0.104608 47.505 0.988553 19.3648 0.014183 69.552 0.984131 17.9371 0.0138117 68.731 0.88372 7.80839 0.0514485 51.951 1 S RPSKTPSPSQPKK CK1;Proline-directed 0.05 0.014183 69.552 _TPpSPSQPK_ TPS(0.989)PS(0.011)QPK T(-53.7)PS(19.36)PS(-19.36)QPK 3 2 461.20751 -0.035636 351600 67807 0 0 283790 0 0 0 2448 1664 1385 1385 2417;6157 2739;2740;7029 22603 14098 Mix4_InSol_Tio2_Reinj_1 2239 60974 36938 Mix4_TiO2_Reinj_1_5 1818 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.449186 0 0.0142897 -18.3872 0.104608 47.505 0.020356 -17.0852 0.00867864 74.828 0.0323537 -12.8178 0.0246995 59.22 0.449186 0 0.0868939 42.32 1 S SKTPSPSQPKKNV CK1 0.143 0.014183 69.552 _GRPSKTPpSPSQPK_ GRPS(0.051)KT(0.051)PS(0.449)PS(0.449)QPK GRPS(-9.46)KT(-9.46)PS(0)PS(0)QPK 10 3 482.90821 2.1862 0 0 0 0 0 0 0 0 2449 1664 1283 1283 3496;3497 3949;3950 33035 20441 Mix4_TiO2_Reinj_1_5 4618 33028 20436 Mix4_TiO2_1_5 4338 Q9NTI5;Q9NTI5-2;Q9NTI5-5 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B;>sp|Q9NTI5-5|PDS5B_HUMAN Isoform 5 of 1 125.889 1 58.1608 1.76895E-20 187.12 1 125.889 3.28424E-09 128.44 1 S NEDEQNSPPKKGK CDK1;CDK2;Proline-directed 0.0057 1.76895E-20 187.12 _LKEDILENEDEQNpSPPKK_ LKEDILENEDEQNS(1)PPKK LKEDILENEDEQNS(125.89)PPKK 14 3 736.01402 0.022372 3064700 715500 0 0 2349200 0 0 0 2450 1664 1165 1165 3851;3852 4359;4360;4361 36511 22524 Mix4_InSol_Tio2_Reinj_1 3972 36496 22515 Mix4_InSol_TiO2_1 3266 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.693905 8.09459 0.617003 2.07106 1.79803E-21 172.08 0 0 0.264898 -4.43269 4.51996E-32 212.25 0.205143 -5.87693 2.57099E-85 305.44 0.693905 8.09459 7.03352E-48 244.16 1 S SSSSNPSSPGRIK CK1 0.081 2.57099E-85 305.44 _METVSNASSSSNPpSSPGRIK_ METVSNAS(0.068)S(0.048)S(0.048)S(0.034)NPS(0.694)S(0.108)PGRIK MET(-48.05)VS(-31.8)NAS(-10.09)S(-11.61)S(-11.61)S(-13.08)NPS(8.09)S(-8.09)PGRIK 14 3 705.98406 -0.061008 380590 230260 0 0 0 0 0 150330 2451 1664 1166 1166 3851;3852 4359;4360;4361 36496 22515 Mix4_InSol_TiO2_1 3266 36496 22515 Mix4_InSol_TiO2_1 3266 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.998938 29.7343 0.992717 21.345 1.79803E-21 172.08 0 0 0.975083 15.9255 4.51996E-32 212.25 0.998938 29.7343 2.57099E-85 305.44 0.997049 25.2869 7.03352E-48 244.16 1 S SSSNPSSPGRIKG CDK1;CDK2;CK1;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 2.57099E-85 305.44 _METVSNASSSSNPSpSPGR_ METVSNASSSSNPS(0.001)S(0.999)PGR MET(-269.36)VS(-232.35)NAS(-156.63)S(-130.57)S(-132.37)S(-116.58)NPS(-29.73)S(29.73)PGR 15 2 937.88294 0.46145 2400400 137840 0 0 1119100 0 685870 457530 2452 1665 22 22 5021 5710;5711 48494 29664 Mix4_TiO2_Reinj_1_5 3659 48494 29664 Mix4_TiO2_Reinj_1_5 3659 Q9NTJ3;Q9NTJ3-2 Q9NTJ3 Q9NTJ3 >sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 PE=1 SV=2;>sp|Q9NTJ3-2|SMC4_HUMAN Isoform 2 of Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 0.999998 54.689 0 0 0.999998 54.689 0.000239054 85.395 0.0125175 -15.9574 0.387321 46.012 0 0 2 S EGPPPPSPDGASS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000239054 85.395 _RREEGPPPPpSPDGApSSDAEPEPPSGR_ RREEGPPPPS(1)PDGAS(0.5)S(0.5)DAEPEPPSGR RREEGPPPPS(54.69)PDGAS(0)S(0)DAEPEPPS(-36.86)GR 10 3 944.39383 -0.53492 531390 0 0 0 531390 0 0 0 2453 1665 27 27 5021 5710;5711 48494 29664 Mix4_TiO2_Reinj_1_5 3659 48494 29664 Mix4_TiO2_Reinj_1_5 3659 Q9NTJ3;Q9NTJ3-2 Q9NTJ3 Q9NTJ3 >sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 PE=1 SV=2;>sp|Q9NTJ3-2|SMC4_HUMAN Isoform 2 of Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 0.499949 0 0 0 0.499949 0 0.000239054 85.395 0.493463 0 0.387321 46.012 0 0 2 S PSPDGASSDAEPE 0.000239054 85.395 _RREEGPPPPpSPDGApSSDAEPEPPSGR_ RREEGPPPPS(1)PDGAS(0.5)S(0.5)DAEPEPPSGR RREEGPPPPS(54.69)PDGAS(0)S(0)DAEPEPPS(-36.86)GR 15 3 944.39383 -0.53492 531390 0 0 0 531390 0 0 0 2454 1665 28 28 5021 5710;5711 48487 29663 Mix4_TiO2_Reinj_1_5 3737 48487 29663 Mix4_TiO2_Reinj_1_5 3737 Q9NTJ3;Q9NTJ3-2 Q9NTJ3 Q9NTJ3 >sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 PE=1 SV=2;>sp|Q9NTJ3-2|SMC4_HUMAN Isoform 2 of Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 0.854567 7.69367 0 0 0.854567 7.69367 2.90264E-07 104.02 0.493463 0 0.387321 46.012 0 0 1 S SPDGASSDAEPEP CK2 0.117 2.90264E-07 104.02 _RREEGPPPPSPDGASpSDAEPEPPSGR_ RREEGPPPPSPDGAS(0.145)S(0.855)DAEPEPPSGR RREEGPPPPS(-44.45)PDGAS(-7.69)S(7.69)DAEPEPPS(-41.19)GR 16 3 917.73839 -0.22025 1144200 0 0 0 1144200 0 0 0 2455 1665 41 41 5971 6809 58958 35765 Mix4_InSol_TiO2_1 6776 58959 35766 Mix4_TiO2_1_5 5611 Q9NTJ3;Q9NTJ3-2 Q9NTJ3 Q9NTJ3 >sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 PE=1 SV=2;>sp|Q9NTJ3-2|SMC4_HUMAN Isoform 2 of Structural maintenance of chromosomes protein 4 OS=Homo sapiens GN=SMC4 0.74523 4.66178 0.624127 2.20234 2.26234E-32 213.37 0.74523 4.66178 6.7374E-21 161.5 0 0 1 S PSGRTESPATAAE CAMK2;Proline-directed 0.042 2.26234E-32 213.37 _TEpSPATAAETASEELDNR_ T(0.255)ES(0.745)PATAAETASEELDNR T(-4.66)ES(4.66)PAT(-45.38)AAET(-94.31)AS(-129.32)EELDNR 3 2 986.41259 0.38416 426290 0.62106 331270 0 0 0 0 95012 0 2456 1667 4538 4538 156;3129 182;3554 1716 1180 Mix4_TiO2_Reinj_1_1 4662 1716 1180 Mix4_TiO2_Reinj_1_1 4662 Q9NU22 Q9NU22 Q9NU22 >sp|Q9NU22|MDN1_HUMAN Midasin OS=Homo sapiens GN=MDN1 PE=1 SV=2 1 103.564 1 89.9532 4.67633E-26 183.64 0.999994 52.2283 4.42531E-10 121.84 1 103.564 1.6713E-39 230.8 1 72.1226 3.94593E-21 161.13 1 87.2489 6.54829E-22 173.5 1 77.5017 7.1896E-26 177.4 1 S ENTDQASPQEDYA CK1;CK2;Proline-directed 0.05 1.6713E-39 230.8 _AEENTDQApSPQEDYAGFER_ AEENTDQAS(1)PQEDYAGFER AEENT(-103.56)DQAS(103.56)PQEDY(-103.82)AGFER 9 2 1118.937 0.44391 3155100 3.0144 439360 28859 0 1667300 33800 519870 465940 2457 1668 486 486 2469 2803;2804 23197 14469 Mix4_TiO2_1_4 3017 23197 14469 Mix4_TiO2_1_4 3017 Q9NUL3;Q9NUL3-2;Q9NUL3-3;Q9NUL3-4 Q9NUL3 Q9NUL3 >sp|Q9NUL3|STAU2_HUMAN Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2 PE=1 SV=1;>sp|Q9NUL3-2|STAU2_HUMAN Isoform Short of Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2;>sp|Q9NUL3-3|STAU2_HUMA 0.871672 8.90402 0.871672 8.90402 7.57852E-05 102.6 0.786205 8.60026 0.00239938 83.196 2.3575E-08 -76.2754 0.00663816 76.275 0 0 1 S IGLKGSSPTPPCS Polo box;Proline-directed 0.00405 7.57852E-05 102.6 _GSpSPTPPCSPVQPSK_ GS(0.112)S(0.872)PT(0.016)PPCSPVQPSK GS(-8.9)S(8.9)PT(-17.34)PPCS(-42.8)PVQPS(-102.6)K 3 2 803.35256 1.0071 190060 46280 0 0 143780 0 0 0 2458 1668 492 492 2469 2803;2804 23196 14468 Mix4_InSol_TiO2_1 3400 23197 14469 Mix4_TiO2_1_4 3017 Q9NUL3;Q9NUL3-2;Q9NUL3-3;Q9NUL3-4 Q9NUL3 Q9NUL3 >sp|Q9NUL3|STAU2_HUMAN Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2 PE=1 SV=1;>sp|Q9NUL3-2|STAU2_HUMAN Isoform Short of Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2;>sp|Q9NUL3-3|STAU2_HUMA 0.999983 47.8054 0.997692 26.0884 0.0232851 61.686 1 65.3803 6.22946E-05 105.38 0.999983 47.8054 0.00663816 76.275 0 0 1 S SPTPPCSPVQPSK CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 7.57852E-05 102.6 _GSSPTPPCpSPVQPSK_ GSSPTPPCS(1)PVQPSK GS(-76.28)S(-76.28)PT(-68.19)PPCS(47.81)PVQPS(-47.81)K 9 2 803.35256 -0.96255 47371 0 0 0 0 0 47371 0 2459 1668 440 440 6443 7371 65081 39931 Mix4_TiO2_1_4 5557 65081 39931 Mix4_TiO2_1_4 5557 Q9NUL3;Q9NUL3-2;Q9NUL3-3;Q9NUL3-4 Q9NUL3 Q9NUL3 >sp|Q9NUL3|STAU2_HUMAN Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2 PE=1 SV=1;>sp|Q9NUL3-2|STAU2_HUMAN Isoform Short of Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2;>sp|Q9NUL3-3|STAU2_HUMA 0.999996 54.1033 0.999996 54.1033 0.000513172 102.21 0.999988 49.9281 0.0150191 67.297 0 0 1 S TTLGYLSPKDMNQ CDK1;CK2;Proline-directed 0.0057 0.000513172 102.21 _VISGTTLGYLpSPK_ VISGTTLGYLS(1)PK VIS(-102.21)GT(-90.9)T(-83.11)LGY(-54.1)LS(54.1)PK 11 2 708.36273 0.52728 80027 37723 42304 0 0 0 0 0 2460 1671 191 191 6496 7433 65628 40246 Mix4_TiO2_Reinj_1_2 2604 65628 40246 Mix4_TiO2_Reinj_1_2 2604 Q9NV56 Q9NV56 Q9NV56 >sp|Q9NV56|MRGBP_HUMAN MRG-binding protein OS=Homo sapiens GN=MRGBP PE=1 SV=1 0.795412 8.80059 0.383247 0 0.459094 27.707 0.795412 8.80059 0.0192237 65.245 1 S KVLTANSNPSSPS GSK3 0.081 0.0192237 65.245 _VLTANpSNPSSPSAAK_ VLTANS(0.795)NPS(0.105)S(0.097)PS(0.003)AAK VLT(-63.37)ANS(8.8)NPS(-8.8)S(-9.15)PS(-24.24)AAK 6 2 762.3587 -0.81879 51126 0 0 0 51126 0 0 0 2461 1671 194 194 6496 7433 65627 40245 Mix4_TiO2_1_2 1982 65628 40246 Mix4_TiO2_Reinj_1_2 2604 Q9NV56 Q9NV56 Q9NV56 >sp|Q9NV56|MRGBP_HUMAN MRG-binding protein OS=Homo sapiens GN=MRGBP PE=1 SV=1 0.383247 0 0.383247 0 0.459094 27.707 0.104842 -8.80059 0.0192237 65.245 1 S TANSNPSSPSAAK CK1 0.081 0.0192237 65.245 _VLTANpSNPSSPSAAK_ VLT(0.001)ANS(0.383)NPS(0.383)S(0.197)PS(0.036)AAK VLT(-27.71)ANS(0)NPS(0)S(-2.88)PS(-10.33)AAK 9 2 762.3587 0.030894 0 0 0 0 0 0 0 0 2462 1672 455 455 3767 4251;4252 35633 22024 Mix4_TiO2_Reinj_1_3 2790 35630 22021 Mix4_TiO2_1_3 1927 Q9NV70-2;Q9NV70 Q9NV70-2 Q9NV70-2 >sp|Q9NV70-2|EXOC1_HUMAN Isoform 2 of Exocyst complex component 1 OS=Homo sapiens GN=EXOC1;>sp|Q9NV70|EXOC1_HUMAN Exocyst complex component 1 OS=Homo sapiens GN=EXOC1 PE=1 SV=4 0.721327 8.90176 0.700049 8.46523 0.0345065 51.131 0 0 0.721327 8.90176 0.043523 48.146 1 S SGKLTGSTSSLNK NEK6 0.076 0.0345065 51.131 _LTGpSTSSLNK_ LTGS(0.721)T(0.093)S(0.093)S(0.093)LNK LT(-48.15)GS(8.9)T(-8.9)S(-8.9)S(-8.9)LNK 4 2 544.25519 -0.61176 156690 22175 0 0 134520 0 0 0 2463 1672 457 457 3767 4251;4252 35630 22021 Mix4_TiO2_1_3 1927 35630 22021 Mix4_TiO2_1_3 1927 Q9NV70-2;Q9NV70 Q9NV70-2 Q9NV70-2 >sp|Q9NV70-2|EXOC1_HUMAN Isoform 2 of Exocyst complex component 1 OS=Homo sapiens GN=EXOC1;>sp|Q9NV70|EXOC1_HUMAN Exocyst complex component 1 OS=Homo sapiens GN=EXOC1 PE=1 SV=4 0.842423 9.38804 0.842423 9.38804 0.0345065 51.131 0 0 0.592783 1.45326 0.072029 40.39 1 S KLTGSTSSLNKLS CK1 0.143 0.0345065 51.131 _LTGSTpSSLNK_ LTGST(0.097)S(0.842)S(0.06)LNK LT(-51.13)GS(-39.84)T(-9.39)S(9.39)S(-11.44)LNK 6 2 544.25519 -1.4589 31244 31244 0 0 0 0 0 0 2464 1672 458 458 3767 4251;4252 35634 22025 Mix4_TiO2_Reinj_1_5 2688 35630 22021 Mix4_TiO2_1_3 1927 Q9NV70-2;Q9NV70 Q9NV70-2 Q9NV70-2 >sp|Q9NV70-2|EXOC1_HUMAN Isoform 2 of Exocyst complex component 1 OS=Homo sapiens GN=EXOC1;>sp|Q9NV70|EXOC1_HUMAN Exocyst complex component 1 OS=Homo sapiens GN=EXOC1 PE=1 SV=4 0.491138 0 0.427234 -2.03882 0.0063405 62.303 0 0 0.491138 0 0.043523 48.146 1 S LTGSTSSLNKLSV CK1 0.081 0.0345065 51.131 _LTGSTpSSLNK_ LT(0.001)GS(0.002)T(0.014)S(0.491)S(0.491)LNK LT(-26.02)GS(-23.02)T(-15.44)S(0)S(0)LNK 7 2 544.25519 -1.546 0 0 0 0 0 0 0 0 2465 1673 4 4 585;586 669;670;671;672;673 5578 3310 Mix4_TiO2_Reinj_1_4 3227 5578 3310 Mix4_TiO2_Reinj_1_4 3227 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.581638 1.43353 0.502645 0.439048 0.0826274 51.808 3.89554E-05 -43.1504 0.0421029 53.183 0.581638 1.43353 8.49126E-06 102.03 0.182638 -5.76768 0.440889 31.8 0.517844 0.696615 0.613422 26.222 3 S ___MATSPQKSPS CDK1;CDK2;GSK3;Proline-directed 0.0057 8.49126E-06 102.03 _(ac)ATpSPQKpSPSVPKpSPTPK_ AT(0.419)S(0.582)PQKS(0.982)PS(0.018)VPKS(0.995)PT(0.005)PK AT(-1.43)S(1.43)PQKS(17.38)PS(-17.38)VPKS(23.06)PT(-23.06)PK 3 2 1009.9355 0.73692 776420 146990 0 0 629430 0 0 0 2466 1673 8 8 585;586;5586;5587 669;670;671;672;673;6366;6367;6368 5524 3288 Mix4_InSol_Tio2_Reinj_1 3377 54627 33445 Mix4_TiO2_Reinj_1_4 2819 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.858123 8.56392 0.777131 6.21192 3.36928E-12 139.43 0.804658 6.15136 0.0421029 53.183 0.956648 15.4954 0.00136366 85.836 0.708455 4.55107 0.008112 76.642 0.858123 8.56392 0.170329 34.065 1 S ATSPQKSPSVPKS CK1;Proline-directed 0.05 0.00184375 92.943 _(ac)ATSPQKpSPSVPK_ AT(0.011)S(0.011)PQKS(0.858)PS(0.119)VPK AT(-18.84)S(-18.84)PQKS(8.56)PS(-8.56)VPK 7 2 674.82905 0.2324 5229800 1185400 140250 0 3510500 0 215650 177970 2467 1673 10 10 585;586;5586;5587 669;670;671;672;673;6366;6367;6368 5528 3293 Mix4_TiO2_Reinj_1_2 2705 54627 33445 Mix4_TiO2_Reinj_1_4 2819 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.910693 12.7623 0.698883 4.45305 3.36928E-12 139.43 0.195198 -6.15136 0.0421029 53.183 0.910693 12.7623 0.00184375 92.943 0.248431 -4.55107 0.008112 76.642 0.119442 -8.56392 0.170329 34.065 1 S SPQKSPSVPKSPT GSK3 0.081 0.00184375 92.943 _(ac)ATSPQKSPpSVPK_ AT(0.021)S(0.021)PQKS(0.048)PS(0.911)VPK AT(-16.47)S(-16.47)PQKS(-12.76)PS(12.76)VPK 9 2 674.82905 0.17032 164920 0 0 0 164920 0 0 0 2468 1673 14 14 586;5586;5587;5592 671;672;673;6366;6367;6368;6373;6374 54626 33443 Mix4_TiO2_2_4 2329 54627 33445 Mix4_TiO2_Reinj_1_4 2819 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.974185 17.5711 0.966279 17.0954 0.00677479 70.354 0.974185 17.5711 0.280212 23.465 0.840528 7.21868 0.00184375 92.943 0.962412 18.0853 0.0357626 58.634 0.97378 17.2739 0.389168 32.582 1 S SPSVPKSPTPKSP CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.00184375 92.943 _SPSVPKpSPTPK_ S(0.004)PS(0.004)VPKS(0.974)PT(0.017)PK S(-23.47)PS(-23.47)VPKS(17.57)PT(-17.57)PK 7 2 602.8023 0.30194 1499100 259890 39130 0 1146400 0 26112 27552 2469 1673 28 28 3080 3501 29328 18297 Mix4_TiO2_Reinj_1_4 3517 29328 18297 Mix4_TiO2_Reinj_1_4 3517 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 1 57.9165 0 0 1 57.9165 0.0156961 57.917 1 S SRKKDDSFLGKLG PLK1 0.033462 0.0156961 57.917 _KKDDpSFLGK_ KKDDS(1)FLGK KKDDS(57.92)FLGK 5 2 559.2681 0.59938 70976 0 0 0 70976 0 0 0 2470 1673 19 19 5587;5592 6367;6368;6373;6374 54690 33487 Mix4_InSol_TiO2_1 2282 54695 33498 Mix4_TiO2_1_4 1565 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.99993 46.3015 0.976591 17.1126 0.0207847 55.674 0 0 0.997972 27.1473 0.0270068 53.614 0.99993 46.3015 0.0284454 53.138 0.991499 25.4392 0.0339533 51.314 1 S KSPTPKSPPSRKK ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0207847 55.674 _SPTPKpSPPSR_ SPTPKS(1)PPSR S(-46.3)PT(-46.3)PKS(46.3)PPS(-46.3)R 6 3 378.51654 -0.095717 8224600 1182700 0 0 6313200 0 409760 318930 2471 1673 22 22 5587;5592 6367;6368;6373;6374 54692 33491 Mix4_InSol_Tio2_Reinj_1 2238 54695 33498 Mix4_TiO2_1_4 1565 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.990903 20.3832 0.107752 -9.23525 3.36928E-12 139.43 0 0 0.192307 -6.17546 0.0270068 53.614 0.729797 4.49235 0.0357626 58.634 0.990903 20.3832 0.0339533 51.314 1 S TPKSPPSRKKDDS CK1 0.081 0.0207847 55.674 _SPTPKSPPpSR_ SPTPKS(0.009)PPS(0.991)R S(-51.31)PT(-47.46)PKS(-20.38)PPS(20.38)R 9 2 567.27117 -0.29893 1376600 0 0 0 0 0 759070 617530 2472 1677 321 321 3579 4035 33721 20779 Mix4_TiO2_Reinj_1_3 7545 33721 20779 Mix4_TiO2_Reinj_1_3 7545 Q9NVI7-2;Q9NVI7 Q9NVI7-2 Q9NVI7-2 >sp|Q9NVI7-2|ATD3A_HUMAN Isoform 2 of ATPase family AAA domain-containing protein 3A OS=Homo sapiens GN=ATAD3A;>sp|Q9NVI7|ATD3A_HUMAN ATPase family AAA domain-containing protein 3A OS=Homo sapiens GN=ATAD3A PE=1 SV=2 0.958407 13.6253 0 0 0.958407 13.6253 2.15109E-05 98.113 1 S LEGVVLSPSLEAR ERK/MAPK;Proline-directed 0.0034 2.15109E-05 98.113 _LLSRPQDALEGVVLpSPSLEAR_ LLSRPQDALEGVVLS(0.958)PS(0.042)LEAR LLS(-95.45)RPQDALEGVVLS(13.63)PS(-13.63)LEAR 15 3 777.4087 -1.2675 321700 0.45982 0 0 0 321700 0 0 0 2473 1679 289 289 884 997 8407 5115 Mix4_TiO2_1_5 2223 8407 5115 Mix4_TiO2_1_5 2223 Q9NWH9 Q9NWH9 Q9NWH9 >sp|Q9NWH9|SLTM_HUMAN SAFB-like transcription modulator OS=Homo sapiens GN=SLTM PE=1 SV=2 0.999999 62.416 0.999999 62.416 3.2583E-07 128.55 0.990311 20.0949 0.0284105 59.635 1 S QDAIAQSPEKESK CDK1;CDK2;Proline-directed 0.0057 3.2583E-07 128.55 _DGQDAIAQpSPEKESK_ DGQDAIAQS(1)PEKESK DGQDAIAQS(62.42)PEKES(-62.42)K 9 2 841.86709 0.14008 359530 182190 0 0 177340 0 0 0 2474 1682 31 31 2595 2951 24264 15083 Mix4_TiO2_Reinj_1_5 2248 24261 15078 Mix4_TiO2_Reinj_1_2 1828 Q9NWW5 Q9NWW5 Q9NWW5 >sp|Q9NWW5|CLN6_HUMAN Ceroid-lipofuscinosis neuronal protein 6 OS=Homo sapiens GN=CLN6 PE=1 SV=1 0.999989 49.4667 0.99991 40.4344 0.00332545 78.84 0.998577 28.4607 0.089426 39.795 0.999989 49.4667 0.00276719 82.664 0.994951 22.946 0.117866 37.36 0.999793 36.8365 0.0339074 53.408 0.994255 22.3823 0.0125471 59.743 1 S LQARHGSVSADEA CAMK2 0.002856 0.00276719 82.664 _HGpSVSADEAAR_ HGS(1)VSADEAAR HGS(49.47)VS(-49.47)ADEAAR 3 2 590.24314 0.0049845 7994200 111.56 544670 52381 0 6029700 21140 674460 671880 2475 1684 979 979 2408 2729 22493 14038 Mix4_TiO2_1_5 6805 22493 14038 Mix4_TiO2_1_5 6805 Q9NX05 Q9NX05 Q9NX05 >sp|Q9NX05|F120C_HUMAN Constitutive coactivator of PPAR-gamma-like protein 2 OS=Homo sapiens GN=FAM120C PE=2 SV=2 1 49.9527 1 49.9527 0.0952119 49.953 2 S SSRGRGSFGMQVV AURORA;PKA 0.038874 0.0952119 49.953 _GRGpSFGMQVVpSVGGPGK_ GRGS(1)FGMQVVS(1)VGGPGK GRGS(49.95)FGMQVVS(49.95)VGGPGK 4 2 890.38609 -1.5959 67758 67758 0 0 0 0 0 0 2476 1684 986 986 2408 2729 22493 14038 Mix4_TiO2_1_5 6805 22493 14038 Mix4_TiO2_1_5 6805 Q9NX05 Q9NX05 Q9NX05 >sp|Q9NX05|F120C_HUMAN Constitutive coactivator of PPAR-gamma-like protein 2 OS=Homo sapiens GN=FAM120C PE=2 SV=2 1 49.9527 1 49.9527 0.0952119 49.953 2 S FGMQVVSVGGPGK 0.0952119 49.953 _GRGpSFGMQVVpSVGGPGK_ GRGS(1)FGMQVVS(1)VGGPGK GRGS(49.95)FGMQVVS(49.95)VGGPGK 11 2 890.38609 -1.5959 67758 67758 0 0 0 0 0 0 2477 1687 113 113 1790 2021 16492 9947 Mix4_TiO2_Reinj_1_6 2304 16492 9947 Mix4_TiO2_Reinj_1_6 2304 Q9NX63 Q9NX63 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial OS=Homo sapiens GN=CHCHD3 PE=1 SV=1 1 62.3659 0 0 1 62.3659 0.00752206 62.366 1 S LRERICSEEERAK CAMK2;CK2;PKA/AKT 0.001764 0.00752206 62.366 _ERICpSEEER_ ERICS(1)EEER ERICS(62.37)EEER 5 2 644.25539 0.086381 115290 2.3546 0 0 0 115290 0 0 0 2478 1687 46 46 5637;5638 6422;6423 55032 33690 Mix4_TiO2_Reinj_1_6 4226 55024 33680 Mix4_InSol_Tio2_Reinj_1 5297 Q9NX63 Q9NX63 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial OS=Homo sapiens GN=CHCHD3 PE=1 SV=1 0.747182 4.75529 0.741367 4.57576 7.3982E-21 160.09 0 0 0.747182 4.75529 2.48509E-15 142.56 0.558852 1.05748 0.0856368 51.706 0.703743 3.75774 3.20897E-31 198.49 0.462671 2.45572 1.43592E-38 219.09 1 S SPSGSKSQRYSGA CK1;GSK3 0.081 1.43592E-38 219.09 _pSQRYSGAYGASVSDEELK_ S(0.747)QRY(0.003)S(0.25)GAYGASVSDEELK S(4.76)QRY(-24.2)S(-4.76)GAY(-57.24)GAS(-68.69)VS(-68.69)DEELK 1 2 1013.9413 0.32082 4766100 431550 0 0 1335700 17255 2981600 0 2479 1687 50 50 5637;5638;6794;6795 6422;6423;7773;7775 68951 42287 Mix4_TiO2_1_6 3757 55024 33680 Mix4_InSol_Tio2_Reinj_1 5297 Q9NX63 Q9NX63 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial OS=Homo sapiens GN=CHCHD3 PE=1 SV=1 1 86.2355 1 86.2355 1.13428E-12 174.16 0.996181 24.1647 0.0175553 66.707 1 69.6489 6.9551E-12 165.07 0.99986 42.7533 0.0856368 51.706 1 71.2775 3.20897E-31 198.49 0.999999 61.2319 1.43592E-38 219.09 1 S SKSQRYSGAYGAS CK1;PKA 0.042 1.43592E-38 219.09 _YpSGAYGASVSDEELK_ YS(1)GAYGASVSDEELK Y(-86.24)S(86.24)GAY(-118.12)GAS(-120.92)VS(-152.57)DEELK 2 2 828.34546 0.025457 14890000 68.84 2597000 20250 0 9701600 51450 574640 1945500 2480 1687 58 58 5637;5638;6794;6795 6422;6423;7773;7775 68950 42285 Mix4_TiO2_1_6 3613 55024 33680 Mix4_InSol_Tio2_Reinj_1 5297 Q9NX63 Q9NX63 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial OS=Homo sapiens GN=CHCHD3 PE=1 SV=1 0.959267 15.1675 0.959267 15.1675 1.13428E-12 174.16 2.12619E-07 -66.7074 0.0175553 66.707 0.92119 10.6777 6.9551E-12 165.07 0.00437902 -23.5095 0.0856368 51.706 0.193871 -5.80636 3.20897E-31 198.49 0.111333 -5.57647 1.43592E-38 219.09 1 S AYGASVSDEELKR CK2 0.117 1.43592E-38 219.09 _YSGAYGASVpSDEELK_ YS(0.029)GAYGAS(0.011)VS(0.959)DEELK Y(-35.7)S(-15.17)GAY(-53.26)GAS(-19.3)VS(15.17)DEELK 10 2 828.34546 0.043189 86519 0.39999 21304 0 0 65215 0 0 0 2481 1688 766 766 2194 2484 20134 12395 Mix4_TiO2_Reinj_1_3 4759 20133 12394 Mix4_TiO2_1_3 3995 Q9NXC5 Q9NXC5 Q9NXC5 >sp|Q9NXC5|MIO_HUMAN WD repeat-containing protein mio OS=Homo sapiens GN=MIOS PE=1 SV=2 0.982004 19.5652 0.943538 12.234 0.00228475 90.995 0.982004 19.5652 0.0108377 72.263 1 S QYGVSGSPTKSKV CDK1;CDK2;GSK3;Proline-directed 0.0057 0.00228475 90.995 _GFSQYGVSGpSPTK_ GFSQYGVS(0.007)GS(0.982)PT(0.011)K GFS(-72.26)QY(-60.39)GVS(-21.38)GS(19.57)PT(-19.57)K 10 2 697.80303 0.93885 233560 50801 0 0 182760 0 0 0 2482 1689 799 799 2613 2974 24440 15167 Mix4_TiO2_Reinj_1_5 4750 24439 15166 Mix4_TiO2_Reinj_1_3 4692 Q9NXE4-4;Q9NXE4;Q9NXE4-2;Q9NXE4-3;Q9NXE4-5 Q9NXE4-4 Q9NXE4-4 >sp|Q9NXE4-4|NSMA3_HUMAN Isoform 4 of Sphingomyelin phosphodiesterase 4 OS=Homo sapiens GN=SMPD4;>sp|Q9NXE4|NSMA3_HUMAN Sphingomyelin phosphodiesterase 4 OS=Homo sapiens GN=SMPD4 PE=1 SV=2;>sp|Q9NXE4-2|NSMA3_HUMAN Isoform 2 of Sphingomyelin phosphodiestera 1 19.8443 1 53.6156 0.0648772 53.616 0 0 1 19.8443 0.0207444 61.563 1 S ASRHLLSPVGRRQ Proline-directed 0.05 0.0207444 61.563 _HLLpSPVGR_ HLLS(1)PVGR HLLS(19.84)PVGR 4 2 479.74713 -0.21588 276020 38877 0 0 237140 0 0 0 2483 1693 224 224 4172;4173 4752;4753 39802 24558 Mix4_InSol_Tio2_Reinj_1 3880 39794 24554 Mix4_InSol_TiO2_1 3093 Q9NYB9;Q9NYB9-2;Q9NYB9-3 Q9NYB9 Q9NYB9 >sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens GN=ABI2 PE=1 SV=1;>sp|Q9NYB9-2|ABI2_HUMAN Isoform 2 of Abl interactor 2 OS=Homo sapiens GN=ABI2;>sp|Q9NYB9-3|ABI2_HUMAN Isoform Abi-2a of Abl interactor 2 OS=Homo sapiens GN=ABI2 0.287113 0.821525 0 0 0.0401771 -13.219 0.00444805 76.078 0.287113 0.821525 0.00502812 74.651 1 S TRNMAPSQQSPVR 0.00444805 76.078 _NMAPpSQQSPVRTASVNQR_ NMAPS(0.287)QQS(0.238)PVRT(0.238)AS(0.238)VNQR NMAPS(0.82)QQS(-0.82)PVRT(-0.82)AS(-0.82)VNQR 5 2 1025.978 -0.32715 0 0 0 0 0 0 0 0 2484 1693 227 227 4172;4173 4752;4753 39795 24555 Mix4_InSol_Tio2_Reinj_1 3103 39794 24554 Mix4_InSol_TiO2_1 3093 Q9NYB9;Q9NYB9-2;Q9NYB9-3 Q9NYB9 Q9NYB9 >sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens GN=ABI2 PE=1 SV=1;>sp|Q9NYB9-2|ABI2_HUMAN Isoform 2 of Abl interactor 2 OS=Homo sapiens GN=ABI2;>sp|Q9NYB9-3|ABI2_HUMAN Isoform Abi-2a of Abl interactor 2 OS=Homo sapiens GN=ABI2 0.998822 29.2837 0 0 0.998493 28.2123 0.00444805 76.078 0.998822 29.2837 0.00502812 74.651 1 S MAPSQQSPVRTAS CDK1;CDK2;CK1;Proline-directed 0.0057 0.00444805 76.078 _NMAPSQQpSPVR_ NMAPS(0.001)QQS(0.999)PVR NMAPS(-29.28)QQS(29.28)PVR 8 2 647.78412 0.49288 129450 0 0 0 0 0 74874 54572 2485 1693 242 242 6317 7217 63203 38510 Mix4_TiO2_Reinj_1_3 1599 63204 38511 Mix4_TiO2_Reinj_1_4 1594 Q9NYB9;Q9NYB9-2;Q9NYB9-3 Q9NYB9 Q9NYB9 >sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens GN=ABI2 PE=1 SV=1;>sp|Q9NYB9-2|ABI2_HUMAN Isoform 2 of Abl interactor 2 OS=Homo sapiens GN=ABI2;>sp|Q9NYB9-3|ABI2_HUMAN Isoform Abi-2a of Abl interactor 2 OS=Homo sapiens GN=ABI2 0.976884 18.76 0.976884 18.76 9.10941E-09 125.29 1 S QRNRTYSSSGSSG CAMK2;GSK3;PKA/AKT 0.00111111 9.10941E-09 125.29 _TYpSSSGSSGGSHPSSR_ T(0.001)Y(0.001)S(0.977)S(0.013)S(0.002)GS(0.001)S(0.001)GGS(0.001)HPS(0.001)S(0.001)R T(-28.3)Y(-29.32)S(18.76)S(-18.76)S(-27.29)GS(-29.32)S(-29.32)GGS(-29.32)HPS(-29.32)S(-29.32)R 3 2 810.81793 0.059756 105330 0 0 0 105330 0 0 0 2486 1694 162 162 2438 2764 22911 14330 Mix4_TiO2_Reinj_1_4 3026 22911 14330 Mix4_TiO2_Reinj_1_4 3026 Q9NYF3 Q9NYF3 Q9NYF3 >sp|Q9NYF3|FA53C_HUMAN Protein FAM53C OS=Homo sapiens GN=FAM53C PE=1 SV=1 0.999959 43.8349 0.999959 43.8349 0.143193 43.835 1 S PQVPHQSPPKRVS CDK1;CDK2;Proline-directed 0.0057 0.143193 43.835 _GSGGGGGPQVPHQpSPPKR_ GSGGGGGPQVPHQS(1)PPKR GS(-43.83)GGGGGPQVPHQS(43.83)PPKR 14 3 593.94772 0.75787 71523 0 0 0 71523 0 0 0 2487 1694 273 273 5685 6475 55689 34133 Mix4_TiO2_Reinj_1_4 3083 55689 34133 Mix4_TiO2_Reinj_1_4 3083 Q9NYF3 Q9NYF3 Q9NYF3 >sp|Q9NYF3|FA53C_HUMAN Protein FAM53C OS=Homo sapiens GN=FAM53C PE=1 SV=1 0.822798 6.66826 0 0 0.822798 6.66826 0.0987663 38.995 1 S NLPRSRSQPCDLD 14-3-3 binding;CAMK2;CHK1;CHK1/2;PKD 0.0001701 0.0987663 38.995 _SRpSQPCDLDAR_ S(0.177)RS(0.823)QPCDLDAR S(-6.67)RS(6.67)QPCDLDAR 3 2 692.78739 -0.25416 91895 0 0 0 91895 0 0 0 2488 1695 385 385 160 187 1751 1197 Mix4_TiO2_Reinj_1_5 6953 1751 1197 Mix4_TiO2_Reinj_1_5 6953 Q9NYF8;Q9NYF8-2;Q9NYF8-3 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 0.774527 7.3759 0 0 0.774527 7.3759 0.000519448 80.857 1 S EALDYFSDKESGK CK2;GSK3 0.081 0.000519448 80.857 _AEGEWEDQEALDYFpSDKESGK_ AEGEWEDQEALDY(0.142)FS(0.775)DKES(0.084)GK AEGEWEDQEALDY(-7.38)FS(7.38)DKES(-9.66)GK 15 3 838.33912 0.50756 248960 0 0 0 248960 0 0 0 2489 1695 397 397 2025 2295 18538 11226 Mix4_TiO2_Reinj_1_5 4235 18538 11226 Mix4_TiO2_Reinj_1_5 4235 Q9NYF8;Q9NYF8-2;Q9NYF8-3 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 1 98.2492 1 109.633 1.45436E-33 226.16 1 98.2492 5.0438E-34 231.13 1 S KQKFNDSEGDDTE CK2 0.117 5.0438E-34 231.13 _FNDpSEGDDTEETEDYR_ FNDS(1)EGDDTEETEDYR FNDS(98.25)EGDDT(-98.25)EET(-162.92)EDY(-231.13)R 4 2 1001.3471 0.15298 239830 68117 0 0 171710 0 0 0 2490 1695 658 658 2719;4912 3098;5585 25692 15874 Mix4_TiO2_Reinj_1_5 5961 25691 15872 Mix4_TiO2_Reinj_1_1 5382 Q9NYF8;Q9NYF8-2;Q9NYF8-3;Q9NYF8-4 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 0.977253 18.6997 0 0 0.977253 18.6997 0.030734 53.155 0.829816 9.23767 0.382785 20.221 0.217303 -5.24191 0.508744 15.998 1 S HRRIDISPSTLRK Proline-directed 0.05 0.030734 53.155 _IDIpSPSTLR_ IDIS(0.977)PS(0.01)T(0.013)LR IDIS(18.7)PS(-20.09)T(-18.7)LR 4 2 541.2681 -0.28203 257320 0 0 0 213050 0 44274 0 2491 1695 660 660 2719;4912 3098;5585 25691 15872 Mix4_TiO2_Reinj_1_1 5382 25691 15872 Mix4_TiO2_Reinj_1_1 5382 Q9NYF8;Q9NYF8-2;Q9NYF8-3;Q9NYF8-4 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 0.56234 1.67485 0 0 0.56234 1.67485 0.030734 53.155 0.0989042 -9.23767 0.382785 20.221 0.0561635 -11.118 0.508744 15.998 1 S RIDISPSTLRKHT 0.030734 53.155 _IDISPpSTLR_ IDIS(0.382)PS(0.562)T(0.055)LR IDIS(-1.67)PS(1.67)T(-10.08)LR 6 2 541.2681 0.18541 35286 0 0 0 35286 0 0 0 2492 1695 177 177 2963;2964 3371;3372 28253 17558 Mix4_TiO2_Reinj_1_5 3163 28253 17558 Mix4_TiO2_Reinj_1_5 3163 Q9NYF8;Q9NYF8-2;Q9NYF8-3;Q9NYF8-4 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 1 98.5022 1 95.5241 0.00131242 95.524 1 98.5022 0.000676206 98.502 0.999985 48.3316 0.000479797 96.187 0.991774 20.8122 0.021334 63.396 1 S GEPQEESPLKSKS CDK1;CDK2;GSK3;Proline-directed 0.0057 0.000676206 98.502 _KAEGEPQEEpSPLK_ KAEGEPQEES(1)PLK KAEGEPQEES(98.5)PLK 10 2 761.34526 0.25025 243750 32904 0 0 90378 0 67758 52714 2493 1695 181 181 2964 3372 28255 17560 Mix4_InSol_TiO2_1 3200 28255 17560 Mix4_InSol_TiO2_1 3200 Q9NYF8;Q9NYF8-2;Q9NYF8-3;Q9NYF8-4 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 0.999943 42.4202 0 0 0 0 0.999943 42.4202 0.000479797 96.187 0.998266 27.6027 0.021334 63.396 1 S EESPLKSKSQEEP CK1 0.143 0.000479797 96.187 _KAEGEPQEESPLKpSK_ KAEGEPQEESPLKS(1)K KAEGEPQEES(-42.42)PLKS(42.42)K 14 2 868.90876 0.2362 99539 0 0 0 0 0 54601 44938 2494 1695 496 496 3013;3014 3427;3428 28783 17921 Mix4_InSol_TiO2_1 2127 28781 17920 Mix4_TiO2_Reinj_1_5 1825 Q9NYF8;Q9NYF8-2;Q9NYF8-3 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 0.960311 15.6472 0 0 0.956403 13.4119 0.051241 45.59 0.960311 15.6472 0.17757 35.614 0.499954 0 0.149359 37.372 1 S VKKETQSPEQVKS Proline-directed 0.05 0.051241 45.59 _KETQpSPEQVKSEK_ KET(0.026)QS(0.96)PEQVKS(0.014)EK KET(-15.65)QS(15.65)PEQVKS(-18.51)EK 5 2 799.37709 -0.036206 160310 0 0 0 85172 0 31460 43674 2495 1696 667 667 1200 1351 11302 6921 Mix4_TiO2_Reinj_1_3 2907 11302 6921 Mix4_TiO2_Reinj_1_3 2907 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.537542 1.24635 0.498214 0 0.00953203 73.739 0.537542 1.24635 8.11488E-12 163.25 1 S SGNTDTSSERGRY 8.11488E-12 163.25 _DSGFSSGNTDTpSSER_ DSGFSSGNTDT(0.059)S(0.538)S(0.403)ER DS(-163.25)GFS(-123.87)S(-85.1)GNT(-45.06)DT(-9.6)S(1.25)S(-1.25)ER 12 2 813.7994 0.038206 123210 0.025684 0 0 0 123210 0 0 0 2496 1696 668 668 1200 1351 11301 6920 Mix4_TiO2_1_3 2296 11302 6921 Mix4_TiO2_Reinj_1_3 2907 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.498214 0 0.498214 0 0.00953203 73.739 0.403438 -1.24635 8.11488E-12 163.25 1 S GNTDTSSERGRYS CK1 0.143 8.11488E-12 163.25 _DSGFSSGNTDTpSSER_ DSGFSSGNT(0.001)DT(0.003)S(0.498)S(0.498)ER DS(-73.74)GFS(-73.74)S(-62.81)GNT(-29.5)DT(-22.18)S(0)S(0)ER 13 2 813.7994 -0.060109 0 0 0 0 0 0 0 0 0 2497 1696 690 690 2446 2773;2774 23008 14383 Mix4_InSol_Tio2_Reinj_2 3009 23005 14380 Mix4_InSol_TiO2_1 4176 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.582318 6.21436 0.00387375 -26.4182 0.186209 30.929 0.0662721 -10.824 9.58625E-05 151.18 0.582318 6.21436 0.000383433 137.19 1 S GSISLNSSPRGRY CK1 0.081 9.58625E-05 151.18 _GSISLNpSSPR_ GS(0.139)IS(0.139)LNS(0.582)S(0.139)PR GS(-6.21)IS(-6.21)LNS(6.21)S(-6.21)PR 7 2 549.25298 0.61786 10239 0 0 0 0 0 0 10239 2498 1696 691 691 2446 2773;2774 23005 14380 Mix4_InSol_TiO2_1 4176 23005 14380 Mix4_InSol_TiO2_1 4176 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 1 63.5213 0.996126 26.4182 0.186209 30.929 1 63.5213 9.58625E-05 151.18 0.999994 52.4992 0.000383433 137.19 1 S SISLNSSPRGRYS CDK1;CK1;NEK6;Polo box;Proline-directed 0.00405 9.58625E-05 151.18 _GSISLNSpSPR_ GSISLNSS(1)PR GS(-151.18)IS(-137.38)LNS(-63.52)S(63.52)PR 8 2 549.25298 0.40368 413450 0 0 0 0 0 233350 180100 2499 1696 565 565 5187 5905 50233 30705 Mix4_TiO2_Reinj_1_3 7560 50232 30704 Mix4_TiO2_1_3 6754 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.98166 17.286 0.896431 9.39661 1.40336E-15 178.25 0.98166 17.286 2.2416E-11 162.73 1 S GNPGSRSDSSADC 1.40336E-15 178.25 _pSDSSADCQWLDTLR_ S(0.982)DS(0.018)SADCQWLDTLR S(17.29)DS(-17.29)S(-56.45)ADCQWLDT(-162.73)LR 1 2 867.34547 0.32238 251530 63683 0 0 187840 0 0 0 2500 1696 591 591 5648 6434 55145 33747 Mix4_TiO2_1_3 8200 55148 33752 Mix4_TiO2_Reinj_1_3 8890 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.810493 6.31125 0.810493 6.31125 0.000258895 84.303 0.449415 -0.881704 3.44439E-08 116.44 1 S NTSLQRSQSNPIL CK1;NEK6 0.076 3.44439E-08 116.44 _pSQSNPILGSPFFSHFDGQDSYAAAVR_ S(0.81)QS(0.19)NPILGSPFFSHFDGQDSYAAAVR S(6.31)QS(-6.31)NPILGS(-67.7)PFFS(-81.01)HFDGQDS(-83.72)Y(-83.72)AAAVR 1 3 960.09926 -0.2942 567540 567540 0 0 0 0 0 0 2501 1696 593 593 5648 6434 55146 33749 Mix4_TiO2_1_4 8171 55148 33752 Mix4_TiO2_Reinj_1_3 8890 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.845562 7.38394 0.845562 7.38394 0.000258895 84.303 0.824068 6.71644 3.44439E-08 116.44 1 S SLQRSQSNPILGS 14-3-3 binding;CAMK2;CHK1;CHK1/2;PKD 0.0001701 3.44439E-08 116.44 _SQpSNPILGSPFFSHFDGQDSYAAAVR_ S(0.154)QS(0.846)NPILGSPFFSHFDGQDSYAAAVR S(-7.38)QS(7.38)NPILGS(-63.9)PFFS(-66.61)HFDGQDS(-66.61)Y(-66.61)AAAVR 3 3 960.09926 0.83767 3808300 199220 0 0 3609000 0 0 0 2502 1696 603 603 5648 6434 55144 33745 Mix4_TiO2_1_3 8042 55148 33752 Mix4_TiO2_Reinj_1_3 8890 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.484499 2.91604 0.484499 2.91604 0.000258895 84.303 0.0044206 -22.1788 3.44439E-08 116.44 1 S LGSPFFSHFDGQD CK1;CK2 0.117 3.44439E-08 116.44 _SQSNPILGSPFFpSHFDGQDSYAAAVR_ SQSNPILGS(0.248)PFFS(0.484)HFDGQDS(0.134)Y(0.134)AAAVR S(-44.54)QS(-43.93)NPILGS(-2.92)PFFS(2.92)HFDGQDS(-5.58)Y(-5.58)AAAVR 13 3 960.09926 0.02638 0 0 0 0 0 0 0 0 2503 1696 636 636 5748 6551 56503 34506 Mix4_TiO2_1_5 3312 56503 34506 Mix4_TiO2_1_5 3312 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.636538 2.90925 0.636538 2.90925 9.31041E-05 149.1 0 0 0.453306 2.19768 0.00299756 120.32 0 0 0.361034 0 0.00268397 122.25 0.310068 0.803081 0.0020363 90.8 1 S VNQSRSSSPTQYG CK1;PKA 0.042 9.31041E-05 149.1 _SpSSPTQYGLTK_ S(0.038)S(0.637)S(0.326)PTQYGLTK S(-12.28)S(2.91)S(-2.91)PT(-42.44)QY(-123.7)GLT(-149.1)K 2 2 624.77903 0.079227 260560 260560 0 0 0 0 0 0 2504 1696 637 637 5748 6551 56502 34505 Mix4_TiO2_1_4 3317 56503 34506 Mix4_TiO2_1_5 3312 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.970262 18.8861 0.970262 18.8861 9.31041E-05 149.1 0 0 0.880609 11.5663 0.00299756 120.32 0 0 0.74257 6.53966 0.00268397 122.25 0.558364 3.15572 0.0020363 90.8 1 S NQSRSSSPTQYGL CAMK2;CK1;PKA/AKT;Polo box;Proline-directed 0.00111111 9.31041E-05 149.1 _SSpSPTQYGLTK_ S(0.009)S(0.013)S(0.97)PT(0.008)QYGLTK S(-20.44)S(-18.89)S(18.89)PT(-20.61)QY(-57.6)GLT(-65.87)K 3 2 624.77903 0.25051 13031000 2458700 0 0 6380300 0 2482800 1709100 2505 1696 727 727 6607;6608;6609 7563;7564;7565;7566 67057 41158 Mix4_TiO2_1_3 3484 67060 41164 Mix4_TiO2_Reinj_1_3 4033 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 1 80.0365 1 80.0365 1.31051E-05 99.753 0 0 1 75.0476 5.5407E-06 110.37 0.999914 41.4432 0.0198629 64.855 0.998512 31.2787 0.426296 31.279 1 S ALNPHQSPDFKRS Proline-directed 0.05 5.5407E-06 110.37 _VSQSALNPHQpSPDFKR_ VSQSALNPHQS(1)PDFKR VS(-80.43)QS(-80.04)ALNPHQS(80.04)PDFKR 11 3 630.96678 0.11075 7925700 1190400 0 0 5180300 0 896010 658890 2506 1696 733 733 6609 7565;7566 67076 41168 Mix4_TiO2_Reinj_1_3 3920 67076 41168 Mix4_TiO2_Reinj_1_3 3920 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.999836 37.863 0.946193 17.2226 1.08045 17.223 0.999836 37.863 0.000876648 83.926 1 S SPDFKRSPRDLHQ CDK1;CK2;NIMA;Proline-directed 0.001741464 0.000876648 83.926 _VSQSALNPHQSPDFKRpSPR_ VSQSALNPHQSPDFKRS(1)PR VS(-83.93)QS(-78.62)ALNPHQS(-37.86)PDFKRS(37.86)PR 17 3 744.36209 -0.59413 750240 20212 0 0 730020 0 0 0 2507 1696 633 633 6782 7760 68760 42175 Mix4_TiO2_Reinj_1_3 3857 68760 42175 Mix4_TiO2_Reinj_1_3 3857 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 1 93.5456 1 82.5288 0.00168033 94.762 0 0 1 93.5456 0.000562678 135.36 1 69.8796 0.00168033 94.762 1 78.0682 0.00363911 78.068 1 S ITPVNQSRSSSPT GSK3 0.081 0.000562678 135.36 _YQQITPVNQpSR_ YQQITPVNQS(1)R Y(-135.36)QQIT(-93.55)PVNQS(93.55)R 10 2 707.32975 -0.27685 1732900 313940 0 0 1224200 0 125740 68989 2508 1697 326 326 3760 4241 35519 21932 Mix4_TiO2_2_4 6319 35519 21932 Mix4_TiO2_2_4 6319 Q9NYL2-2 Q9NYL2-2 Q9NYL2-2 >sp|Q9NYL2-2|MLTK_HUMAN Isoform Beta of Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK 0.975163 16.8641 0 0 0.975163 16.8641 0.00167189 85.823 0 0 1 S QKLTEQSNTPLLL 0.00167189 85.823 _LTEQpSNTPLLLPLAAR_ LT(0.02)EQS(0.975)NT(0.005)PLLLPLAAR LT(-16.86)EQS(16.86)NT(-23.11)PLLLPLAAR 5 2 908.98206 0.098358 19289 0.61729 0 19289 0 0 0 0 0 2509 1699 1082 1082 1879;3016;4323 2122;3430;4916 28797 17926 Mix4_TiO2_Reinj_1_1 2518 17275 10387 Mix4_TiO2_Reinj_1_1 2719 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.499999 0 0.00690183 -21.577 0.000274518 87.234 0 0 0.499999 0 8.35051E-12 128.95 0 0 0 0 0 0 1 S TEPVKNSSPAPPQ 8.35051E-12 128.95 _KETTSGTSTEPVKNpSSPAPPQPAPGK_ KETTSGTSTEPVKNS(0.5)S(0.5)PAPPQPAPGK KET(-64.45)T(-65.47)S(-65.47)GT(-57.66)S(-58.73)T(-59.78)EPVKNS(0)S(0)PAPPQPAPGK 15 3 891.76376 -1.5721 248320 0 0 0 248320 0 0 0 2510 1699 1083 1083 1879;3016;4323 2122;3430;4916 41067 25264 Mix4_TiO2_Reinj_1_1 2124 17275 10387 Mix4_TiO2_Reinj_1_1 2719 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.996529 24.5804 0.992342 21.577 0.000274518 87.234 0 0 0.996529 24.5804 8.35051E-12 128.95 0 0 0 0 0 0 1 S EPVKNSSPAPPQP Polo box;Proline-directed 0.00405 8.35051E-12 128.95 _NSpSPAPPQPAPGK_ NS(0.003)S(0.997)PAPPQPAPGK NS(-24.58)S(24.58)PAPPQPAPGK 3 2 664.30574 0.15537 1127400 82241 0 0 1045100 0 0 0 2511 1699 681 681 2614 2975;2976 24450 15173 Mix4_TiO2_Reinj_1_5 8305 24450 15173 Mix4_TiO2_Reinj_1_5 8305 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.984233 17.9535 0.863408 8.00831 0.325541 48.438 0.984233 17.9535 0.0003054 81.686 1 S LPGGDLSPPDSPE CK2;GSK3;Proline-directed 0.05 0.0003054 81.686 _HLLTDLPLPPELPGGDLpSPPDSPEPK_ HLLTDLPLPPELPGGDLS(0.984)PPDS(0.016)PEPK HLLT(-81.69)DLPLPPELPGGDLS(17.95)PPDS(-17.95)PEPK 18 3 937.79992 -0.1908 209420 45994 0 0 163430 0 0 0 2512 1699 685 685 2614 2975;2976 24445 15171 Mix4_TiO2_Reinj_1_5 8564 24445 15171 Mix4_TiO2_Reinj_1_5 8564 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 1 106.498 0.999999 58.8768 0.0596399 58.877 1 106.498 2.39235E-07 106.5 2 S DLSPPDSPEPKAI CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.39235E-07 106.5 _HLLTDLPLPPELPGGDLpSPPDpSPEPK_ HLLTDLPLPPELPGGDLS(1)PPDS(1)PEPK HLLT(-106.5)DLPLPPELPGGDLS(106.5)PPDS(106.5)PEPK 22 3 964.45537 0.26531 568250 120250 0 0 448000 0 0 0 2513 1699 889 889 3807 4302 36170 22368 Mix4_TiO2_Reinj_1_5 3435 36166 22364 Mix4_TiO2_1_5 2849 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.337635 0 0.117069 -8.40824 0.0004559 104.18 0 0 0.337635 0 0.00269506 89.051 0 0 0 0 0.121669 -5.98491 0.860187 5.9849 1 S LYNSEESRPYTNK CK1 0.081 0.0004559 104.18 _LYNSEEpSRPYTNK_ LY(0.006)NS(0.008)EES(0.338)RPY(0.311)T(0.338)NK LY(-17.67)NS(-16.47)EES(0)RPY(-0.35)T(0)NK 7 3 560.91369 0.028434 0 0 0 0 0 0 0 0 2514 1702 261 261 6403 7325 64680 39679 Mix4_TiO2_Reinj_1_2 2210 64680 39679 Mix4_TiO2_Reinj_1_2 2210 Q9NZ63 Q9NZ63 Q9NZ63 >sp|Q9NZ63|CI078_HUMAN Uncharacterized protein C9orf78 OS=Homo sapiens GN=C9orf78 PE=1 SV=1 0.995584 23.5309 0.995584 23.5309 0.143442 42.112 0 0 0 0 1 S KPEPERSPPNRKR Proline-directed 0.05 0.143442 42.112 _VGDTEKPEPERpSPPNR_ VGDT(0.004)EKPEPERS(0.996)PPNR VGDT(-23.53)EKPEPERS(23.53)PPNR 12 3 629.95807 -0.23316 52932 0 0 0 52932 0 0 0 2515 1703 383 383 4452 5063 42308 26033 Mix4_TiO2_Reinj_1_1 7132 42309 26034 Mix4_TiO2_Reinj_1_5 7588 Q9NZB2;Q9NZB2-4;Q9NZB2-6;Q9NZB2-5;Q9NZB2-2;Q5T035 Q9NZB2 Q9NZB2 >sp|Q9NZB2|F120A_HUMAN Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens GN=FAM120A PE=1 SV=2;>sp|Q9NZB2-4|F120A_HUMAN Isoform D of Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens GN=FAM120A;>sp|Q9NZB2-6|F120A_HUMA 0.999981 48.5425 0.999662 35.0622 2.40638E-07 105.48 0 0 0.999981 48.5425 3.2159E-12 126.79 1 S VAPQVPSPGGAPG ERK/MAPK;Proline-directed 0.0034 3.2159E-12 126.79 _PVAPQVPpSPGGAPGQGPYPYSLSEPAPLTLDTSGK_ PVAPQVPS(1)PGGAPGQGPYPYSLSEPAPLTLDTSGK PVAPQVPS(48.54)PGGAPGQGPY(-48.54)PY(-53.26)S(-63.84)LS(-68.61)EPAPLT(-93.56)LDT(-104.8)S(-104.8)GK 8 3 1171.571 0.70543 5261600 1202300 0 0 4059300 0 0 0 2516 1704 4264 4264 1183 1329 11107 6808 Mix4_InSol_Tio2_Reinj_1 7864 11110 6812 Mix4_TiO2_Reinj_1_1 6836 Q9NZJ4;Q9NZJ4-2 Q9NZJ4 Q9NZJ4 >sp|Q9NZJ4|SACS_HUMAN Sacsin OS=Homo sapiens GN=SACS PE=1 SV=2;>sp|Q9NZJ4-2|SACS_HUMAN Isoform 2 of Sacsin OS=Homo sapiens GN=SACS 0.837205 10.1315 0.302302 -1.11589 0.0578213 55.643 0.219415 0 1.54523 4.2811 0.298458 -1.30323 7.08564E-07 114.96 0.0877516 -8.52179 0.000862965 84.159 0.837205 10.1315 0.00320189 77.457 1 S APSTPTSPTEFLT CK1;CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 7.08564E-07 114.96 _DSAPSTPTpSPTEFLTPGLR_ DSAPSTPT(0.081)S(0.837)PT(0.081)EFLTPGLR DS(-64.53)APS(-39.12)T(-39.12)PT(-10.13)S(10.13)PT(-10.13)EFLT(-37.74)PGLR 9 2 1027.4775 0.17734 205940 0 0 0 0 0 0 205940 2517 1704 1779 1779 2690;2691 3063;3064 25283 15607 Mix4_TiO2_1_1 7216 25280 15604 Mix4_TiO2_1_1 5774 Q9NZJ4;Q9NZJ4-2 Q9NZJ4 Q9NZJ4 >sp|Q9NZJ4|SACS_HUMAN Sacsin OS=Homo sapiens GN=SACS PE=1 SV=2;>sp|Q9NZJ4-2|SACS_HUMAN Isoform 2 of Sacsin OS=Homo sapiens GN=SACS 1 59.4667 1 59.4667 0.00313913 126.36 0 0 1 105.706 0.00301789 105.71 1 S RIADLQSPLFRGP Proline-directed 0.05 0.00313913 126.36 _IADLQpSPLFRGPDDDPAALFEM(ox)AK_ IADLQS(1)PLFRGPDDDPAALFEMAK IADLQS(59.47)PLFRGPDDDPAALFEMAK 6 3 905.09082 -0.14342 474850 135850 0 0 339000 0 0 0 2518 1705 555 555 3009 3423 28763 17912 Mix4_TiO2_1_5 4820 28763 17912 Mix4_TiO2_1_5 4820 Q9NZJ5 Q9NZJ5 Q9NZJ5 >sp|Q9NZJ5|E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Homo sapiens GN=EIF2AK3 PE=1 SV=3 0.758955 5.0008 0.758955 5.0008 0.0001893 86.684 0 0 1 S HRQRKESETQCQT CAMK2;PKA;PKA/AKT 0.001764 0.0001893 86.684 _KEpSETQCQTENKYDSVSGEANDSSWNDIK_ KES(0.759)ET(0.24)QCQT(0.001)ENKYDSVSGEANDSSWNDIK KES(5)ET(-5)QCQT(-28.75)ENKY(-40.05)DS(-67.48)VS(-74.98)GEANDS(-83.21)S(-85.49)WNDIK 3 3 1143.8069 -0.86706 55204 55204 0 0 0 0 0 0 2519 1705 1094 1094 5681 6469 55656 34103 Mix4_TiO2_Reinj_1_5 1599 55656 34103 Mix4_TiO2_Reinj_1_5 1599 Q9NZJ5 Q9NZJ5 Q9NZJ5 >sp|Q9NZJ5|E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 OS=Homo sapiens GN=EIF2AK3 PE=1 SV=3 0.973929 18.6834 0 0 0.973929 18.6834 0.0588669 43.065 1 S LRQRSRSLSSSGT CAMK2;GSK3;PKA/AKT 0.00111111 0.0588669 43.065 _SRpSLSSSGTK_ S(0.013)RS(0.974)LS(0.013)SSGTK S(-18.83)RS(18.68)LS(-18.68)S(-43.07)S(-43.07)GT(-43.07)K 3 2 545.25044 -0.10272 129690 0 0 0 129690 0 0 0 2520 1707 165 165 6120 6985;6986 60467 36563 Mix4_InSol_Tio2_Reinj_1 3670 60467 36563 Mix4_InSol_Tio2_Reinj_1 3670 Q9NZN8;Q9NZN8-5;Q9NZN8-4 Q9NZN8 Q9NZN8 >sp|Q9NZN8|CNOT2_HUMAN CCR4-NOT transcription complex subunit 2 OS=Homo sapiens GN=CNOT2 PE=1 SV=1;>sp|Q9NZN8-5|CNOT2_HUMAN Isoform 5 of CCR4-NOT transcription complex subunit 2 OS=Homo sapiens GN=CNOT2;>sp|Q9NZN8-4|CNOT2_HUMAN Isoform 4 of CCR4-NOT transc 0.999998 56.7916 0.999983 49.0362 0.0235718 60.431 0.937854 12.0264 0.0250805 59.926 0.960135 14.3533 0.0235718 60.431 0.999998 56.7916 3.94188E-05 114.83 1 S SSSGLGSPNRSSP CDK1;CDK2;CK1;GSK3;Proline-directed 0.0057 3.94188E-05 114.83 _TNSMSSSGLGpSPNR_ TNSMSSSGLGS(1)PNR T(-114.83)NS(-114.83)MS(-87.36)S(-73.6)S(-56.79)GLGS(56.79)PNR 11 2 737.80324 0.59839 238340 15002 0 0 54428 0 22853 146060 2521 1709 135 135 3406;3696 3848;4168 32060 19814 Mix4_TiO2_Reinj_1_5 5916 34821 21606 Mix4_TiO2_Reinj_1_1 5853 Q9P035 Q9P035 Q9P035 >sp|Q9P035|HACD3_HUMAN 3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens GN=PTPLAD1 PE=1 SV=2 0.999556 34.1678 0 0 0 0 0.999556 34.1678 0.0391722 58.134 0 0 0 0 1 S NKLRLESEGSPET CAMK2 0.042 0.0391722 58.134 _LEpSEGSPETLTNLR_ LES(1)EGSPETLTNLR LES(34.17)EGS(-34.17)PET(-42.42)LT(-53.9)NLR 3 2 813.37455 0.041664 222630 0 0 0 222630 0 0 0 2522 1709 114 114 4990;6686 5673;7655;7656 67844 41670 Mix4_TiO2_Reinj_2_1 4678 67809 41634 Mix4_TiO2_Reinj_1_5 6922 Q9P035 Q9P035 Q9P035 >sp|Q9P035|HACD3_HUMAN 3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens GN=PTPLAD1 PE=1 SV=2 1 67.3539 1 95.9153 9.31533E-05 123.83 1 73.6681 0.000163798 117.38 1 89.5786 1.39858E-05 137.51 1 67.3539 0.0110869 71.268 1 83.8692 9.9935E-05 122.67 1 66.0638 0.000588279 109.35 1 S DRWLDESDAEMEL CK2;NEK6 0.076 1.39858E-05 137.51 _WLDEpSDAEMELR_ WLDES(1)DAEMELR WLDES(67.35)DAEMELR 5 2 787.31565 0.10833 36554000 8579500 477680 0 25966000 130320 871150 530280 2523 1713 463 463 3114 3537 29641 18451 Mix4_InSol_Tio2_Reinj_1 2949 29643 18453 Mix4_TiO2_Reinj_1_3 2587 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.987426 19.3866 0.757567 8.1711 0.379254 18.158 0.86553 8.81613 0.000785468 80.041 0.775722 8.39959 0.0325161 51.79 0.987426 19.3866 0.061445 42.212 1 S VARKLGSTTVGSK 0.000785468 80.041 _KLGpSTTVGSK_ KLGS(0.987)T(0.011)T(0.001)VGSK KLGS(19.39)T(-19.39)T(-29.37)VGS(-42.21)K 4 2 529.2681 0.81484 950450 71639 0 0 677660 0 88051 113100 2524 1713 423 423 4868 5534 46690 28588 Mix4_TiO2_Reinj_1_3 5362 46690 28588 Mix4_TiO2_Reinj_1_3 5362 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.999998 63.3665 0.999998 63.3665 0.0199266 63.366 0 0 0 0 1 S QKQRRFSDHAGPS CAMK2;PKA 0.004788 0.0199266 63.366 _RFpSDHAGPSIPPAVSYTK_ RFS(1)DHAGPSIPPAVSYTK RFS(63.37)DHAGPS(-63.37)IPPAVS(-63.37)Y(-63.37)T(-63.37)K 3 3 670.65421 -0.264 230100 0 0 0 230100 0 0 0 2525 1713 649 649 4903 5575 47068 28781 Mix4_InSol_Tio2_Reinj_1 3455 47068 28781 Mix4_InSol_Tio2_Reinj_1 3455 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.718818 6.30528 0.157948 -7.09273 0.314734 20.944 0.455587 0 0.408562 16.892 0.290217 -1.59921 0.143952 34.43 0.718818 6.30528 0.0525145 45.169 1 S HARRGTSTGIISK CAMK2 0.042 0.0525145 45.169 _RGTpSTGIISK_ RGT(0.168)S(0.719)T(0.113)GIISK RGT(-6.31)S(6.31)T(-8.04)GIIS(-45.17)K 4 2 550.279 0.33516 414080 0 0 0 0 0 0 414080 2526 1713 588 588 6519 7459 65856 40345 Mix4_InSol_Tio2_Reinj_1 4214 65857 40346 Mix4_TiO2_1_3 3287 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.734374 8.63297 0.00314345 -24.7666 7.69541E-21 159.43 0 0 0.0635642 -11.6773 3.69825E-06 107.74 0.151378 -0.79901 0.00129194 83.131 0.734374 8.63297 1.12409 12.616 1 S QRVPAASPSAHSI Proline-directed 0.05 7.69541E-21 159.43 _VPAApSPSAHSISTATPDR_ VPAAS(0.734)PS(0.101)AHS(0.044)IS(0.04)T(0.04)AT(0.04)PDR VPAAS(8.63)PS(-8.63)AHS(-12.18)IS(-12.62)T(-12.62)AT(-12.62)PDR 5 3 615.6228 0.73641 29651 0 0 0 0 0 0 29651 2527 1713 590 590 6519 7459 65858 40347 Mix4_TiO2_Reinj_1_3 3894 65857 40346 Mix4_TiO2_1_3 3287 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.935291 11.6773 0.0392969 -13.797 7.69541E-21 159.43 0 0 0.935291 11.6773 3.69825E-06 107.74 0.934534 12.7787 0.00129194 83.131 0.100605 -8.63297 1.12409 12.616 1 S VPAASPSAHSIST 7.69541E-21 159.43 _VPAASPpSAHSISTATPDR_ VPAAS(0.064)PS(0.935)AHS(0.001)ISTATPDR VPAAS(-11.68)PS(11.68)AHS(-29.16)IS(-52.78)T(-52.78)AT(-85.56)PDR 7 2 922.93055 0.093584 307000 0 0 0 264380 0 42625 0 2528 1713 593 593 6519 7459 65857 40346 Mix4_TiO2_1_3 3287 65857 40346 Mix4_TiO2_1_3 3287 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.942025 13.797 0.942025 13.797 7.69541E-21 159.43 0 0 0.00113529 -29.1584 3.69825E-06 107.74 0.181955 0 0.00129194 83.131 0.0444083 -12.1845 1.12409 12.616 1 S ASPSAHSISTATP CK1 0.081 7.69541E-21 159.43 _VPAASPSAHpSISTATPDR_ VPAAS(0.003)PS(0.039)AHS(0.942)IS(0.014)T(0.001)ATPDR VPAAS(-24.77)PS(-13.8)AHS(13.8)IS(-18.26)T(-28.07)AT(-60.78)PDR 10 2 922.93055 -0.047448 108480 108480 0 0 0 0 0 0 2529 1713 595 595 6519 7459 65855 40344 Mix4_InSol_TiO2_2 3166 65857 40346 Mix4_TiO2_1_3 3287 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.181955 0 0.014063 -18.2599 7.69541E-21 159.43 0 0 4.92883E-06 -52.782 3.69825E-06 107.74 0.181955 0 0.00129194 83.131 0.0402042 -12.6165 1.12409 12.616 1 S PSAHSISTATPDR 7.69541E-21 159.43 _VPAASPSAHpSISTATPDR_ VPAAS(0.151)PS(0.151)AHS(0.182)IS(0.182)T(0.182)AT(0.151)PDR VPAAS(-0.8)PS(-0.8)AHS(0)IS(0)T(0)AT(-0.8)PDR 12 2 922.93055 0.029916 0 0 0 0 0 0 0 0 2530 1714 296 296 5133 5839 49644 30333 Mix4_TiO2_1_5 6988 49644 30333 Mix4_TiO2_1_5 6988 Q9P0V3;Q9P0V3-2 Q9P0V3 Q9P0V3 >sp|Q9P0V3|SH3B4_HUMAN SH3 domain-binding protein 4 OS=Homo sapiens GN=SH3BP4 PE=1 SV=1;>sp|Q9P0V3-2|SH3B4_HUMAN Isoform 2 of SH3 domain-binding protein 4 OS=Homo sapiens GN=SH3BP4 1 81.2821 1 81.2821 4.1235E-26 169.08 1 73.4069 1.78813E-18 151.58 1 S HRKLARSCHDLDL CK2;NEK6 0.076 4.1235E-26 169.08 _pSCHDLDLLGQSPGWGQTQAVETNIVCK_ S(1)CHDLDLLGQSPGWGQTQAVETNIVCK S(81.28)CHDLDLLGQS(-81.28)PGWGQT(-144.66)QAVET(-161.91)NIVCK 1 3 1031.7984 0.51343 560280 145420 0 0 414850 0 0 0 2531 1714 244 244 5876 6701 57941 35207 Mix4_TiO2_1_5 6780 57943 35209 Mix4_TiO2_Reinj_1_3 7667 Q9P0V3;Q9P0V3-2 Q9P0V3 Q9P0V3 >sp|Q9P0V3|SH3B4_HUMAN SH3 domain-binding protein 4 OS=Homo sapiens GN=SH3BP4 PE=1 SV=1;>sp|Q9P0V3-2|SH3B4_HUMAN Isoform 2 of SH3 domain-binding protein 4 OS=Homo sapiens GN=SH3BP4 0.499997 0 0.499997 0 2.59118E-13 179.44 0 0 0.00979353 -20.0466 2.13963E-13 182.19 0.00668949 -21.7162 3.12597E-06 145.8 0.00526096 -22.7663 2.30361E-05 129.97 1 S FFRSKRSYSLSEL CK1;GSK3 0.081 2.13963E-13 182.19 _pSYSLSELSVLQAK_ S(0.5)YS(0.5)LSELSVLQAK S(0)Y(-87.78)S(0)LS(-48.74)ELS(-126.11)VLQAK 1 2 752.86837 -0.040351 371200 371200 0 0 0 0 0 0 2532 1714 246 246 5876 6701 57939 35204 Mix4_TiO2_1_1 6329 57943 35209 Mix4_TiO2_Reinj_1_3 7667 Q9P0V3;Q9P0V3-2 Q9P0V3 Q9P0V3 >sp|Q9P0V3|SH3B4_HUMAN SH3 domain-binding protein 4 OS=Homo sapiens GN=SH3BP4 PE=1 SV=1;>sp|Q9P0V3-2|SH3B4_HUMAN Isoform 2 of SH3 domain-binding protein 4 OS=Homo sapiens GN=SH3BP4 0.998936 30.1278 0.998936 30.1278 2.59118E-13 179.44 0 0 0.992321 21.1183 2.13963E-13 182.19 0.993153 21.7162 3.12597E-06 145.8 0.994699 22.7663 2.30361E-05 129.97 1 S RSKRSYSLSELSV CAMK2;CK2;PKA;PKA/AKT 0.00111111 2.13963E-13 182.19 _SYpSLSELSVLQAK_ S(0.001)YS(0.999)LSELSVLQAK S(-30.13)Y(-72.59)S(30.13)LS(-40.24)ELS(-93.23)VLQAK 3 2 752.86837 -0.21468 2178600 508120 0 0 1323300 0 221780 125330 2533 1715 3 3 529 601 4947 2985 Mix4_TiO2_1_5 5498 4946 2983 Mix4_TiO2_1_5 5490 Q9P1Q0;Q9P1Q0-2;Q9P1Q0-4 Q9P1Q0 Q9P1Q0 >sp|Q9P1Q0|VPS54_HUMAN Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54 PE=1 SV=2;>sp|Q9P1Q0-2|VPS54_HUMAN Isoform 2 of Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54;>sp|Q9P1Q0-4|VPS54_HUMAN Isoform 4 of Vac 0.399604 0 0.399604 0 5.31347E-07 112.8 0.000590796 -31.8729 0.000447764 86.538 1 S ____MASSHSSSP GSK3 0.081 5.31347E-07 112.8 _(ac)ApSSHSSSPVPQGSSSDVFFK_ AS(0.4)S(0.4)HS(0.087)S(0.023)S(0.023)PVPQGS(0.023)S(0.023)S(0.023)DVFFK AS(0)S(0)HS(-6.62)S(-12.41)S(-12.41)PVPQGS(-12.47)S(-12.47)S(-12.47)DVFFK 2 3 720.64756 -0.21481 0 0 0 0 0 0 0 0 2534 1715 4 4 529 601 4947 2985 Mix4_TiO2_1_5 5498 4946 2983 Mix4_TiO2_1_5 5490 Q9P1Q0;Q9P1Q0-2;Q9P1Q0-4 Q9P1Q0 Q9P1Q0 >sp|Q9P1Q0|VPS54_HUMAN Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54 PE=1 SV=2;>sp|Q9P1Q0-2|VPS54_HUMAN Isoform 2 of Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54;>sp|Q9P1Q0-4|VPS54_HUMAN Isoform 4 of Vac 0.399604 0 0.399604 0 5.31347E-07 112.8 0.000590796 -31.8729 0.000447764 86.538 1 S ___MASSHSSSPV GSK3 0.081 5.31347E-07 112.8 _(ac)ApSSHSSSPVPQGSSSDVFFK_ AS(0.4)S(0.4)HS(0.087)S(0.023)S(0.023)PVPQGS(0.023)S(0.023)S(0.023)DVFFK AS(0)S(0)HS(-6.62)S(-12.41)S(-12.41)PVPQGS(-12.47)S(-12.47)S(-12.47)DVFFK 3 3 720.64756 -0.21481 0 0 0 0 0 0 0 0 2535 1715 6 6 529 601 4946 2983 Mix4_TiO2_1_5 5490 4946 2983 Mix4_TiO2_1_5 5490 Q9P1Q0;Q9P1Q0-2;Q9P1Q0-4 Q9P1Q0 Q9P1Q0 >sp|Q9P1Q0|VPS54_HUMAN Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54 PE=1 SV=2;>sp|Q9P1Q0-2|VPS54_HUMAN Isoform 2 of Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54;>sp|Q9P1Q0-4|VPS54_HUMAN Isoform 4 of Vac 0.427359 1.36398 0.427359 1.36398 5.31347E-07 112.8 0.0115307 -18.9687 0.000447764 86.538 1 S _MASSHSSSPVPQ CK1 0.081 5.31347E-07 112.8 _(ac)ASSHpSSSPVPQGSSSDVFFK_ AS(0.016)S(0.016)HS(0.427)S(0.312)S(0.229)PVPQGSSSDVFFK AS(-14.35)S(-14.35)HS(1.36)S(-1.36)S(-2.71)PVPQGS(-36.34)S(-63.45)S(-62.47)DVFFK 5 2 1080.4677 0.43885 0 0 0 0 0 0 0 0 2536 1715 8 8 529 601 4948 2986 Mix4_TiO2_Reinj_1_5 6402 4946 2983 Mix4_TiO2_1_5 5490 Q9P1Q0;Q9P1Q0-2;Q9P1Q0-4 Q9P1Q0 Q9P1Q0 >sp|Q9P1Q0|VPS54_HUMAN Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54 PE=1 SV=2;>sp|Q9P1Q0-2|VPS54_HUMAN Isoform 2 of Vacuolar protein sorting-associated protein 54 OS=Homo sapiens GN=VPS54;>sp|Q9P1Q0-4|VPS54_HUMAN Isoform 4 of Vac 0.909335 13.4657 0.228971 -2.71012 5.31347E-07 112.8 0.909335 13.4657 0.000447764 86.538 1 S ASSHSSSPVPQGS CK1;Polo box;Proline-directed 0.00405 5.31347E-07 112.8 _(ac)ASSHSSpSPVPQGSSSDVFFK_ AS(0.001)S(0.001)HS(0.012)S(0.041)S(0.909)PVPQGS(0.025)S(0.005)S(0.007)DVFFK AS(-31.87)S(-31.87)HS(-18.97)S(-13.47)S(13.47)PVPQGS(-15.65)S(-22.29)S(-21.19)DVFFK 7 2 1080.4677 0.56203 423950 0 0 0 423950 0 0 0 2537 1717 180 180 246 283 2473 1562 Mix4_TiO2_Reinj_1_5 7468 2472 1561 Mix4_TiO2_1_5 6625 Q9P260-2;Q9P260 Q9P260-2 Q9P260-2 >sp|Q9P260-2|K1468_HUMAN Isoform 2 of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468;>sp|Q9P260|K1468_HUMAN LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468 PE=1 SV=2 0.999984 48.03 0.999889 39.652 9.66059E-05 109.88 0.999984 48.03 0.000115707 108.23 1 S QLNRAGSISTLDS CAMK2;CHK1;CHK1/2;PKD 0.003192 9.66059E-05 109.88 _AGpSISTLDSLDFAR_ AGS(1)ISTLDSLDFAR AGS(48.03)IS(-48.03)T(-64.93)LDS(-105.34)LDFAR 3 2 766.85325 0.0097587 881970 163780 0 0 718190 0 0 0 2538 1717 56 56 3429 3873 32194 19891 Mix4_TiO2_Reinj_1_5 6569 32194 19891 Mix4_TiO2_Reinj_1_5 6569 Q9P260-2;Q9P260 Q9P260-2 Q9P260-2 >sp|Q9P260-2|K1468_HUMAN Isoform 2 of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468;>sp|Q9P260|K1468_HUMAN LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468 PE=1 SV=2 0.996007 24.6871 0 0 0.996007 24.6871 4.36591E-05 95.926 1 S GSAGSLSPQDPVA CK2;Proline-directed 0.05 4.36591E-05 95.926 _LGAGSGLDPGSAGSLpSPQDPVALGSSAR_ LGAGSGLDPGS(0.003)AGS(0.001)LS(0.996)PQDPVALGSSAR LGAGS(-46.21)GLDPGS(-24.69)AGS(-32.32)LS(24.69)PQDPVALGS(-83.88)S(-90.23)AR 16 3 868.74822 0.55793 397310 0 0 0 397310 0 0 0 2539 1718 4 4 261 298;299 2543 1601 Mix4_TiO2_Reinj_1_4 8353 2543 1601 Mix4_TiO2_Reinj_1_4 8353 Q9P289 Q9P289 Q9P289 >sp|Q9P289|MST4_HUMAN Serine/threonine-protein kinase MST4 OS=Homo sapiens GN=MST4 PE=1 SV=2 1 120.06 0.999998 58.0826 0.0678985 58.083 1 120.06 1.71419E-11 120.06 1 S ___MAHSPVAVQV Proline-directed 0.05 1.71419E-11 120.06 _(ac)AHpSPVAVQVPGMQNNIADPEELFTK_ AHS(1)PVAVQVPGMQNNIADPEELFTK AHS(120.06)PVAVQVPGMQNNIADPEELFT(-120.06)K 3 3 938.77712 0.51096 367800 141680 0 0 226120 0 0 0 2540 1719 1735 1735 6590 7542 66823 40985 Mix4_InSol_Tio2_Reinj_2 2056 66826 40990 Mix4_TiO2_Reinj_1_1 2326 Q9P2D3 Q9P2D3 Q9P2D3 >sp|Q9P2D3|HTR5B_HUMAN HEAT repeat-containing protein 5B OS=Homo sapiens GN=HEATR5B PE=1 SV=2 0.822747 6.75949 0.160868 -7.1652 0.0028372 81.884 0 0 0.176901 -4.23715 0.00238956 86.867 0.231648 -3.46265 0.136576 35.759 0.822747 6.75949 0.0066094 70.761 1 S HLSTKVSDSPSHI CK1;GSK3 0.081 0.00238956 86.867 _VpSDSPSHIATK_ VS(0.823)DS(0.174)PS(0.003)HIATK VS(6.76)DS(-6.76)PS(-23.96)HIAT(-32.7)K 2 2 611.27919 -0.086075 20051 0 0 0 0 0 0 20051 2541 1719 1737 1737 6590 7542 66828 40993 Mix4_TiO2_Reinj_1_5 2774 66826 40990 Mix4_TiO2_Reinj_1_1 2326 Q9P2D3 Q9P2D3 Q9P2D3 >sp|Q9P2D3|HTR5B_HUMAN HEAT repeat-containing protein 5B OS=Homo sapiens GN=HEATR5B PE=1 SV=2 0.984636 18.4571 0.949942 14.9206 0.0028372 81.884 0 0 0.984636 18.4571 0.00238956 86.867 0.254061 -3.06156 0.136576 35.759 0.882833 8.96291 0.0066094 70.761 1 S STKVSDSPSHIAT Proline-directed 0.05 0.00238956 86.867 _VSDpSPSHIATK_ VS(0.001)DS(0.985)PS(0.014)HIATK VS(-28.75)DS(18.46)PS(-18.46)HIAT(-56.12)K 4 2 611.27919 -0.84745 1653300 290710 0 0 1069400 0 0 293180 2542 1719 1739 1739 6590 7542 66821 40983 Mix4_InSol_TiO2_1 2990 66826 40990 Mix4_TiO2_Reinj_1_1 2326 Q9P2D3 Q9P2D3 Q9P2D3 >sp|Q9P2D3|HTR5B_HUMAN HEAT repeat-containing protein 5B OS=Homo sapiens GN=HEATR5B PE=1 SV=2 0.514154 3.06156 0.0305941 -14.9206 0.0028372 81.884 0 0 0.214389 -5.21173 0.00238956 86.867 0.514154 3.06156 0.136576 35.759 0.0050715 -22.4074 0.0066094 70.761 1 S KVSDSPSHIATKT CK1 0.143 0.00238956 86.867 _VSDSPpSHIATK_ VS(0.232)DS(0.254)PS(0.514)HIATK VS(-3.46)DS(-3.06)PS(3.06)HIAT(-35.76)K 6 2 611.27919 0.19194 224930 0 0 0 0 0 224930 0 2543 1721 737 737 2514 2857 23664 14704 Mix4_TiO2_Reinj_1_5 3108 23664 14704 Mix4_TiO2_Reinj_1_5 3108 Q9P2G1 Q9P2G1 Q9P2G1 >sp|Q9P2G1|AKIB1_HUMAN Ankyrin repeat and IBR domain-containing protein 1 OS=Homo sapiens GN=ANKIB1 PE=1 SV=3 1 93.5489 1 48.317 0.0592913 48.317 1 93.5489 0.00260986 93.549 0 0 0 0 1 S GVAPADSPEAPRR Proline-directed 0.05 0.00260986 93.549 _GVAPADpSPEAPR_ GVAPADS(1)PEAPR GVAPADS(93.55)PEAPR 7 2 623.77682 -0.33779 307530 68504 0 0 239020 0 0 0 2544 1723 672 672 2579 2934 24166 15002 Mix4_TiO2_Reinj_1_5 3774 24165 15001 Mix4_TiO2_Reinj_1_5 3769 Q9P2K8;Q9P2K8-2 Q9P2K8 Q9P2K8 >sp|Q9P2K8|E2AK4_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 4 OS=Homo sapiens GN=EIF2AK4 PE=1 SV=3;>sp|Q9P2K8-2|E2AK4_HUMAN Isoform 2 of Eukaryotic translation initiation factor 2-alpha kinase 4 OS=Homo sapiens GN=EIF2AK4 0.949275 12.7217 0.226874 -5.32464 1.50776 5.3246 0 0 0.949275 12.7217 4.05987E-10 123.12 0 0 0 0 1 S GTPPPDSGPLAKD 4.05987E-10 123.12 _HERPAGPGTPPPDpSGPLAK_ HERPAGPGT(0.051)PPPDS(0.949)GPLAK HERPAGPGT(-12.72)PPPDS(12.72)GPLAK 14 2 980.96747 -0.25358 290720 0 0 0 290720 0 0 0 2545 1724 187 187 6610 7567 67088 41171 Mix4_TiO2_Reinj_1_4 2944 67087 41170 Mix4_TiO2_1_4 2527 Q9P2W9 Q9P2W9 Q9P2W9 >sp|Q9P2W9|STX18_HUMAN Syntaxin-18 OS=Homo sapiens GN=STX18 PE=1 SV=1 0.874355 9.05971 0.614873 2.1935 3.71341E-05 97.572 0.874355 9.05971 0.000281884 89.09 1 S TSSEKVSQSPSKD CK1;GSK3 0.081 3.71341E-05 97.572 _VpSQSPSKDSEENPATEERPEK_ VS(0.874)QS(0.109)PS(0.017)KDSEENPATEERPEK VS(9.06)QS(-9.06)PS(-17.13)KDS(-38.96)EENPAT(-48.05)EERPEK 2 2 1212.5318 0.33613 207080 1.8433 135250 0 0 71830 0 0 0 2546 1724 189 189 6610 7567 67089 41172 Mix4_TiO2_Reinj_1_4 2972 67087 41170 Mix4_TiO2_1_4 2527 Q9P2W9 Q9P2W9 Q9P2W9 >sp|Q9P2W9|STX18_HUMAN Syntaxin-18 OS=Homo sapiens GN=STX18 PE=1 SV=1 0.444255 0 0.371052 -2.1935 3.71341E-05 97.572 0.444255 0 0.000281884 89.09 1 S SEKVSQSPSKDSE CDK1;CDK2;Proline-directed 0.0057 3.71341E-05 97.572 _VSQpSPSKDSEENPATEERPEK_ VS(0.109)QS(0.444)PS(0.444)KDS(0.003)EENPATEERPEK VS(-6.12)QS(0)PS(0)KDS(-21.96)EENPAT(-53.43)EERPEK 4 3 808.69026 -0.07076 0 0 0 0 0 0 0 0 0 2547 1724 191 191 6610 7567 67089 41172 Mix4_TiO2_Reinj_1_4 2972 67087 41170 Mix4_TiO2_1_4 2527 Q9P2W9 Q9P2W9 Q9P2W9 >sp|Q9P2W9|STX18_HUMAN Syntaxin-18 OS=Homo sapiens GN=STX18 PE=1 SV=1 0.444255 0 0.0140054 -16.4249 3.71341E-05 97.572 0.444255 0 0.000281884 89.09 1 S KVSQSPSKDSEEN CK1 0.143 3.71341E-05 97.572 _VSQpSPSKDSEENPATEERPEK_ VS(0.109)QS(0.444)PS(0.444)KDS(0.003)EENPATEERPEK VS(-6.12)QS(0)PS(0)KDS(-21.96)EENPAT(-53.43)EERPEK 6 3 808.69026 -0.07076 0 0 0 0 0 0 0 0 0 2548 1726 98 98 2082 2358 19071 11604 Mix4_TiO2_Reinj_1_3 4937 19071 11604 Mix4_TiO2_Reinj_1_3 4937 Q9UBB9 Q9UBB9 Q9UBB9 >sp|Q9UBB9|TFP11_HUMAN Tuftelin-interacting protein 11 OS=Homo sapiens GN=TFIP11 PE=1 SV=1 1 158.953 1 141.085 1.00883E-17 141.08 0 0 1 158.953 2.03694E-25 158.95 1 S EAELEDSDDEEKP CK2;NEK6 0.076 2.03694E-25 158.95 _GAAEEAELEDpSDDEEKPVKQDDFPK_ GAAEEAELEDS(1)DDEEKPVKQDDFPK GAAEEAELEDS(158.95)DDEEKPVKQDDFPK 11 3 957.74124 -0.32032 2001300 680740 0 0 1320600 0 0 0 2549 1727 49 49 5310 6046 51546 31545 Mix4_TiO2_1_1 5366 51546 31545 Mix4_TiO2_1_1 5366 Q9UBC2 Q9UBC2 Q9UBC2 >sp|Q9UBC2|EP15R_HUMAN Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens GN=EPS15L1 PE=1 SV=1 0.999372 32.021 0.999372 32.021 0.0567131 43.779 0 0 0.926631 11.0139 0.251543 25.515 0.948178 12.6237 0.507404 12.624 0 0 1 S LKKSGLSDIILGK CK1 0.081 0.0567131 43.779 _SGLpSDIILGK_ S(0.001)GLS(0.999)DIILGK S(-32.02)GLS(32.02)DIILGK 4 2 541.7783 -0.05022 244450 37860 0 0 175200 0 31383 0 2550 1729 496 496 4939 5615 47499 28991 Mix4_TiO2_Reinj_1_3 5447 47499 28991 Mix4_TiO2_Reinj_1_3 5447 Q9UBF8-2;Q9UBF8;Q9UBF8-3 Q9UBF8-2 Q9UBF8-2 >sp|Q9UBF8-2|PI4KB_HUMAN Isoform NPIK-C of Phosphatidylinositol 4-kinase beta OS=Homo sapiens GN=PI4KB;>sp|Q9UBF8|PI4KB_HUMAN Phosphatidylinositol 4-kinase beta OS=Homo sapiens GN=PI4KB PE=1 SV=1;>sp|Q9UBF8-3|PI4KB_HUMAN Isoform 3 of Phosphatidylinositol 4 0.999984 50.4012 0 0 0.999984 50.4012 0.0612667 51.331 1 S DIRRRLSEQLAHT CAMK2;CHK1;PKA;PKD 0.004788 0.0612667 51.331 _RLpSEQLAHTPTAFK_ RLS(1)EQLAHTPTAFK RLS(50.4)EQLAHT(-50.4)PT(-51.33)AFK 3 3 560.28193 0.48255 197630 0 0 0 197630 0 0 0 2551 1729 294 294 5908 6738 58277 35375 Mix4_TiO2_Reinj_1_3 3184 58277 35375 Mix4_TiO2_Reinj_1_3 3184 Q9UBF8-2 Q9UBF8-2 Q9UBF8-2 >sp|Q9UBF8-2|PI4KB_HUMAN Isoform NPIK-C of Phosphatidylinositol 4-kinase beta OS=Homo sapiens GN=PI4KB 0.982821 17.5746 0 0 0.982821 17.5746 0.0180458 66.302 0.530965 0.538609 1.11303 7.0772 0 0 1 S NLKRTASNPKVEN CAMK2;CHK1;CHK1/2;PKA;PKD 0.003024 0.0180458 66.302 _TApSNPKVENEDEPVR_ T(0.017)AS(0.983)NPKVENEDEPVR T(-17.57)AS(17.57)NPKVENEDEPVR 3 2 882.89364 -0.58465 174220 0 0 0 137260 0 36955 0 2552 1731 14 14 305;5420 348;6168 2838 1741 Mix4_TiO2_1_4 2637 2838 1741 Mix4_TiO2_1_4 2637 Q9UBM7 Q9UBM7 Q9UBM7 >sp|Q9UBM7|DHCR7_HUMAN 7-dehydrocholesterol reductase OS=Homo sapiens GN=DHCR7 PE=1 SV=1 0.999988 49.3618 0.999988 49.3618 0.0475505 49.362 0.999939 42.1167 0.0719796 42.117 0.761981 5.05333 0.654776 5.0533 0.998566 28.4271 0.222242 28.427 1 S NIPKAKSLDGVTN CHK1;PKD 0.020748 0.0475505 49.362 _AKpSLDGVTNDR_ AKS(1)LDGVTNDR AKS(49.36)LDGVT(-49.36)NDR 3 2 628.28755 -0.075097 1107000 12.331 270670 0 0 678230 0 5726.1 152320 2553 1732 22 22 4661;5676 5289;6464 44171 27053 Mix4_TiO2_1_5 2286 44171 27053 Mix4_TiO2_1_5 2286 Q9UBN7 Q9UBN7 Q9UBN7 >sp|Q9UBN7|HDAC6_HUMAN Histone deacetylase 6 OS=Homo sapiens GN=HDAC6 PE=1 SV=2 0.999696 35.8733 0.999696 35.8733 0.0155644 68.453 0 0 0.986619 19.5343 0.123734 42.451 0.996802 30.9577 0.389136 34.255 0.98295 24.5978 0.713704 24.598 1 S SRQNPQSPPQDSS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0155644 68.453 _QNPQpSPPQDSSVTSK_ QNPQS(1)PPQDSSVTSK QNPQS(35.87)PPQDS(-35.87)S(-43.48)VT(-68.24)S(-68.45)K 5 2 840.36726 0.11872 494500 13.187 129970 0 0 81629 0 163590 119310 2554 1732 27 27 4661;5676 5289;6464 44173 27056 Mix4_TiO2_Reinj_1_5 2919 44171 27053 Mix4_TiO2_1_5 2286 Q9UBN7 Q9UBN7 Q9UBN7 >sp|Q9UBN7|HDAC6_HUMAN Histone deacetylase 6 OS=Homo sapiens GN=HDAC6 PE=1 SV=2 0.486561 0.486404 0.000258545 -35.8733 0.0155644 68.453 0 0 0.486561 0.486404 0.123734 42.451 0.0029593 -25.1661 0.389136 34.255 0.00340995 -24.5978 0.713704 24.598 1 S QSPPQDSSVTSKR GSK3 0.081 0.0155644 68.453 _QNPQSPPQDpSSVTSK_ QNPQS(0.435)PPQDS(0.487)S(0.078)VTSK QNPQS(-0.49)PPQDS(0.49)S(-7.93)VT(-42.45)S(-42.45)K 10 2 840.36726 0.079617 0 0 0 0 0 0 0 0 0 2555 1733 423 423 413 471 3911 2335 Mix4_TiO2_Reinj_1_4 3510 3911 2335 Mix4_TiO2_Reinj_1_4 3510 Q9UBS0 Q9UBS0 Q9UBS0 >sp|Q9UBS0|KS6B2_HUMAN Ribosomal protein S6 kinase beta-2 OS=Homo sapiens GN=RPS6KB2 PE=1 SV=2 1 52.457 0 0 0 0 1 52.457 0.113506 52.457 1 S SPRAPVSPLKFSP CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.113506 52.457 _APVpSPLK_ APVS(1)PLK APVS(52.46)PLK 4 2 396.20678 -0.065664 26071 0 0 0 26071 0 0 0 2556 1734 357 357 6809 7792 69081 42357 Mix4_TiO2_Reinj_1_5 6943 69081 42357 Mix4_TiO2_Reinj_1_5 6943 Q9UBU7 Q9UBU7 Q9UBU7 >sp|Q9UBU7|DBF4A_HUMAN Protein DBF4 homolog A OS=Homo sapiens GN=DBF4 PE=1 SV=1 0.621461 2.35435 0 0 0 0 0.621461 2.35435 0.117284 43.612 1 S IKYSVGSLSPVSA CK1 0.081 0.117284 43.612 _YSVGpSLSPVSASVLK_ YS(0.001)VGS(0.621)LS(0.361)PVS(0.016)AS(0.001)VLK Y(-43.61)S(-30.82)VGS(2.35)LS(-2.35)PVS(-15.91)AS(-29.74)VLK 5 2 787.3973 0.0016452 108700 0 0 0 108700 0 0 0 2557 1736 130 130 3260 3695 30845 19144 Mix4_TiO2_Reinj_1_5 5596 30845 19144 Mix4_TiO2_Reinj_1_5 5596 Q9UDY2;Q9UDY2-3;Q9UDY2-2;Q9UDY2-4;Q9UDY2-5 Q9UDY2 Q9UDY2 >sp|Q9UDY2|ZO2_HUMAN Tight junction protein ZO-2 OS=Homo sapiens GN=TJP2 PE=1 SV=1;>sp|Q9UDY2-3|ZO2_HUMAN Isoform C1 of Tight junction protein ZO-2 OS=Homo sapiens GN=TJP2;>sp|Q9UDY2-2|ZO2_HUMAN Isoform A2 of Tight junction protein ZO-2 OS=Homo sapiens GN= 1 66.2193 0 0 1 66.2193 0.0166929 66.219 1 S VAALQASPPLDQD NEK6;Proline-directed 0.05 0.0166929 66.219 _KVQVAALQApSPPLDQDDR_ KVQVAALQAS(1)PPLDQDDR KVQVAALQAS(66.22)PPLDQDDR 10 3 677.6684 -0.057209 84660 0 0 0 84660 0 0 0 2558 1737 28 28 2319 2624 21510 13186 Mix4_TiO2_Reinj_1_4 3964 21509 13184 Mix4_TiO2_Reinj_1_4 3934 Q9UEE5 Q9UEE5 Q9UEE5 >sp|Q9UEE5|ST17A_HUMAN Serine/threonine-protein kinase 17A OS=Homo sapiens GN=STK17A PE=1 SV=1 1 37.4019 1 59.2312 0.0305175 59.231 1 6.12515 1.14681 6.1252 1 37.4019 0.0130463 70.66 1 66.5667 0.0177434 66.567 1 40.0756 0.153699 40.076 1 S RAGRGLSGPCRPP CAMK2 0.042 0.0130463 70.66 _GLpSGPCRPPPPPQAR_ GLS(1)GPCRPPPPPQAR GLS(37.4)GPCRPPPPPQAR 3 2 833.89781 0.16768 7096300 448120 39111 0 4894400 0 1010600 704110 2559 1739 211 211 1954 2212;2213 17893 10698 Mix4_TiO2_1_4 5290 17894 10699 Mix4_TiO2_1_4 5456 Q9UGJ0;Q9UGJ0-3 Q9UGJ0 Q9UGJ0 >sp|Q9UGJ0|AAKG2_HUMAN 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 PE=1 SV=1;>sp|Q9UGJ0-3|AAKG2_HUMAN Isoform C of 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 0.937057 13.2292 0.937057 13.2292 1.22712E-11 128.11 0.808588 6.89324 0.173278 50.841 0.382238 3.42968 1.55049 22.006 0.646038 8.51582 1.56917 21.714 1 S CPSSFQSPTRPPL CDK1;CDK2;CK1;Proline-directed 0.0057 1.22712E-11 128.11 _FCPSSFQpSPTRPPLASPTHYAPSK_ FCPS(0.008)S(0.01)FQS(0.937)PT(0.045)RPPLASPTHYAPSK FCPS(-20.43)S(-19.84)FQS(13.23)PT(-13.23)RPPLAS(-41.33)PT(-40.85)HY(-45.67)APS(-48.82)K 8 3 914.09116 -0.45286 286120 106230 0 0 0 0 0 179890 2560 1739 195 195 2946 3353 28116 17478 Mix4_TiO2_Reinj_1_3 3324 28114 17475 Mix4_TiO2_1_4 2708 Q9UGJ0;Q9UGJ0-3 Q9UGJ0 Q9UGJ0 >sp|Q9UGJ0|AAKG2_HUMAN 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 PE=1 SV=1;>sp|Q9UGJ0-3|AAKG2_HUMAN Isoform C of 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 0.498845 0 0.495998 0 0.000566718 100.37 0.0812293 -10.4415 0.221546 32.872 0.498845 0 0.00463857 79.952 0.154314 -7.18301 0.00234967 90.668 0.177266 -2.15173 0.00274289 88.827 1 S NRIYASSSPPDTG 0.000566718 100.37 _IYASpSSPPDTGQR_ IYAS(0.001)S(0.499)S(0.499)PPDT(0.001)GQR IY(-61.81)AS(-26.91)S(0)S(0)PPDT(-25.86)GQR 5 2 729.81667 -0.080471 0 0 0 0 0 0 0 0 2561 1739 196 196 2946 3353 28110 17468 Mix4_InSol_Tio2_Reinj_2 2473 28114 17475 Mix4_TiO2_1_4 2708 Q9UGJ0;Q9UGJ0-3 Q9UGJ0 Q9UGJ0 >sp|Q9UGJ0|AAKG2_HUMAN 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 PE=1 SV=1;>sp|Q9UGJ0-3|AAKG2_HUMAN Isoform C of 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 0.986798 20.0085 0.869548 8.47884 0.000566718 100.37 0.899208 10.4415 0.221546 32.872 0.979633 19.3951 0.00463857 79.952 0.98673 19.3855 0.00234967 90.668 0.986798 20.0085 0.00274289 88.827 1 S RIYASSSPPDTGQ CK2;Polo box;Proline-directed 0.00405 0.000566718 100.37 _IYASSpSPPDTGQR_ IYAS(0.003)S(0.01)S(0.987)PPDTGQR IY(-59.24)AS(-24.85)S(-20.01)S(20.01)PPDT(-39.11)GQR 6 2 729.81667 0.15111 6794900 984560 91209 0 3616800 0 1240800 861490 2562 1743 61 61 6760 7736 68589 42094 Mix4_TiO2_1_4 3257 68590 42095 Mix4_TiO2_Reinj_1_4 3848 Q9UH62 Q9UH62 Q9UH62 >sp|Q9UH62|ARMX3_HUMAN Armadillo repeat-containing X-linked protein 3 OS=Homo sapiens GN=ARMCX3 PE=1 SV=1 0.999992 51.3584 0.999992 51.3584 0.000142178 98.476 0.999985 48.2893 5.28778E-05 107.35 1 S ARYNDWSDDDDDS CK2 0.117 5.28778E-05 107.35 _YNDWpSDDDDDSNESK_ YNDWS(1)DDDDDSNESK Y(-67.69)NDWS(51.36)DDDDDS(-51.36)NES(-75.99)K 5 2 942.80762 0.57183 242450 51832 0 0 190610 0 0 0 2563 1744 116 116 2491 2830 23434 14575 Mix4_TiO2_1_3 3048 23434 14575 Mix4_TiO2_1_3 3048 Q9UH99 Q9UH99 Q9UH99 >sp|Q9UH99|SUN2_HUMAN SUN domain-containing protein 2 OS=Homo sapiens GN=SUN2 PE=1 SV=3 0.995567 26.3122 0.995567 26.3122 0.131161 43.975 0.46652 2.049 0.340499 34.291 2 S SESSRASGLVGRK CK1;PKA 0.042 0.131161 43.975 _GpTGGSESSRApSGLVGR_ GT(0.778)GGS(0.219)ES(0.004)S(0.004)RAS(0.996)GLVGR GT(5.51)GGS(-5.51)ES(-26.31)S(-26.31)RAS(26.31)GLVGR 11 2 819.33765 0.17105 39958 39958 0 0 0 0 0 0 2564 1744 12 12 3775;6803;6804 4266;7784;7785 69035 42328 Mix4_TiO2_1_3 4763 69046 42330 Mix4_TiO2_Reinj_1_3 5928 Q9UH99 Q9UH99 Q9UH99 >sp|Q9UH99|SUN2_HUMAN SUN domain-containing protein 2 OS=Homo sapiens GN=SUN2 PE=1 SV=3 0.999828 37.6394 0.999828 37.6394 1.73943E-08 117.26 0.486148 1.22889 3.93667E-13 132.81 0 0 0 0 1 S QRLTRYSQGDDDG CK2;PKA 0.042 3.93667E-13 132.81 _YpSQGDDDGSSSSGGSSVAGSQSTLFK_ YS(1)QGDDDGSSSSGGSSVAGSQSTLFK Y(-37.64)S(37.64)QGDDDGS(-73.89)S(-76.23)S(-82.62)S(-85.32)GGS(-91.69)S(-98.51)VAGS(-117.26)QS(-117.26)T(-117.26)LFK 2 2 1296.0245 0.81736 148890 0.02262 148890 0 0 0 0 0 0 2565 1744 54 54 4952 5630 47657 29109 Mix4_TiO2_Reinj_1_3 7995 47657 29109 Mix4_TiO2_Reinj_1_3 7995 Q9UH99 Q9UH99 Q9UH99 >sp|Q9UH99|SUN2_HUMAN SUN domain-containing protein 2 OS=Homo sapiens GN=SUN2 PE=1 SV=3 0.978341 17.8268 0.978341 17.8268 1.39108E-07 100.4 1 S SNMKRLSPAPQLG PKA;Proline-directed 0.042 1.39108E-07 100.4 _RLpSPAPQLGPSSDAHTSYYSESLVHESWFPPR_ RLS(0.978)PAPQLGPS(0.004)S(0.016)DAHT(0.001)SYYSESLVHESWFPPR RLS(17.83)PAPQLGPS(-23.59)S(-17.83)DAHT(-30.42)S(-37)Y(-43.33)Y(-43.33)S(-42.83)ES(-48.93)LVHES(-78.51)WFPPR 3 4 920.43078 0.20193 4254000 0 0 0 4254000 0 0 0 2566 1744 38 38 6804 7785 69046 42330 Mix4_TiO2_Reinj_1_3 5928 69046 42330 Mix4_TiO2_Reinj_1_3 5928 Q9UH99 Q9UH99 Q9UH99 >sp|Q9UH99|SUN2_HUMAN SUN domain-containing protein 2 OS=Homo sapiens GN=SUN2 PE=1 SV=3 0.986124 19.5046 0 0 0.986124 19.5046 3.93667E-13 132.81 1 S STLFKDSPLRTLK CDK1;CDK2;Proline-directed 0.0057 3.93667E-13 132.81 _YSQGDDDGSSSSGGSSVAGSQSTLFKDpSPLR_ YSQGDDDGSSSSGGSSVAGS(0.001)QS(0.011)T(0.002)LFKDS(0.986)PLR Y(-132.81)S(-132.81)QGDDDGS(-119.08)S(-115.35)S(-111.38)S(-111.38)GGS(-94.78)S(-84.69)VAGS(-31.1)QS(-19.5)T(-26.81)LFKDS(19.5)PLR 28 3 1053.7844 0.86936 2474900 0 0 0 2474900 0 0 0 2567 1747 549 549 4600 5222 43635 26758 Mix4_TiO2_Reinj_1_5 1311 43635 26758 Mix4_TiO2_Reinj_1_5 1311 Q9UHB7;Q9UHB7-2 Q9UHB7 Q9UHB7 >sp|Q9UHB7|AFF4_HUMAN AF4/FMR2 family member 4 OS=Homo sapiens GN=AFF4 PE=1 SV=1;>sp|Q9UHB7-2|AFF4_HUMAN Isoform 2 of AF4/FMR2 family member 4 OS=Homo sapiens GN=AFF4 0.992868 21.4902 0 0 0.992868 21.4902 0.0758499 45.321 1 S GRGRQKSPAQSDS CAMK2;GSK3;PKA/AKT;Proline-directed 0.001764 0.0758499 45.321 _QKpSPAQSDSTTQR_ QKS(0.993)PAQS(0.007)DSTTQR QKS(21.49)PAQS(-21.49)DS(-45.32)T(-45.32)T(-45.32)QR 3 2 757.33576 0.59612 31765 0 0 0 31765 0 0 0 2568 1751 82 82 2680 3053 25170 15548 Mix4_TiO2_Reinj_1_3 2225 25169 15547 Mix4_InSol_Tio2_Reinj_1 2694 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7 Q9UHD8 Q9UHD8 >sp|Q9UHD8|SEPT9_HUMAN Septin-9 OS=Homo sapiens GN=SEPT9 PE=1 SV=2;>sp|Q9UHD8-5|SEPT9_HUMAN Isoform Gamma of Septin-9 OS=Homo sapiens GN=SEPT9;>sp|Q9UHD8-2|SEPT9_HUMAN Isoform Alpha of Septin-9 OS=Homo sapiens GN=SEPT9;>sp|Q9UHD8-7|SEPT9_HUMAN Isoform 7 of 0.680137 4.40268 0 0 0 0 0.680137 4.40268 0.123292 36.896 0 0 0.131769 -8.18791 0.00989652 62.674 1 S RHVDSLSQRSPKA 0.00989652 62.674 _HVDSLpSQRSPK_ HVDS(0.073)LS(0.68)QRS(0.247)PK HVDS(-9.69)LS(4.4)QRS(-4.4)PK 6 2 667.31664 -0.14183 229850 0 0 0 229850 0 0 0 2569 1751 85 85 2680 3053 25169 15547 Mix4_InSol_Tio2_Reinj_1 2694 25169 15547 Mix4_InSol_Tio2_Reinj_1 2694 Q9UHD8;Q9UHD8-5;Q9UHD8-2;Q9UHD8-7 Q9UHD8 Q9UHD8 >sp|Q9UHD8|SEPT9_HUMAN Septin-9 OS=Homo sapiens GN=SEPT9 PE=1 SV=2;>sp|Q9UHD8-5|SEPT9_HUMAN Isoform Gamma of Septin-9 OS=Homo sapiens GN=SEPT9;>sp|Q9UHD8-2|SEPT9_HUMAN Isoform Alpha of Septin-9 OS=Homo sapiens GN=SEPT9;>sp|Q9UHD8-7|SEPT9_HUMAN Isoform 7 of 0.868172 8.18791 0 0 0 0 0.246791 -4.40268 0.123292 36.896 0 0 0.868172 8.18791 0.00989652 62.674 1 S DSLSQRSPKASLR CDK1;CK1;GSK3;Proline-directed 0.0057 0.00989652 62.674 _HVDSLSQRpSPK_ HVDSLS(0.132)QRS(0.868)PK HVDS(-41.68)LS(-8.19)QRS(8.19)PK 9 2 667.31664 0.47846 111730 0 0 0 0 0 0 111730 2570 1753 678 678 5873 6697 57912 35194 Mix4_TiO2_1_5 4373 57912 35194 Mix4_TiO2_1_5 4373 Q9UHI6 Q9UHI6 Q9UHI6 >sp|Q9UHI6|DDX20_HUMAN Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens GN=DDX20 PE=1 SV=2 0.85296 7.64207 0.85296 7.64207 0.0036919 76.052 1 S SYLEGSSDNQLKD 0.0036919 76.052 _SYLEGSpSDNQLKDSESTPVDDR_ SYLEGS(0.147)S(0.853)DNQLKDSESTPVDDR S(-50.97)Y(-50.97)LEGS(-7.64)S(7.64)DNQLKDS(-35.77)ES(-56.01)T(-64.37)PVDDR 7 3 841.35706 -0.16595 114240 1.9531 114240 0 0 0 0 0 0 2571 1753 714 714 6774 7751 68686 42139 Mix4_TiO2_Reinj_1_5 3129 68686 42139 Mix4_TiO2_Reinj_1_5 3129 Q9UHI6 Q9UHI6 Q9UHI6 >sp|Q9UHI6|DDX20_HUMAN Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens GN=DDX20 PE=1 SV=2 0.999962 44.1876 0 0 0.999962 44.1876 0.0554777 44.188 1 S PEKYQESPGIQMK Proline-directed 0.05 0.0554777 44.188 _YQEpSPGIQM(ox)K_ YQES(1)PGIQMK Y(-44.19)QES(44.19)PGIQMK 4 2 638.7676 -0.31759 45296 0 0 0 45296 0 0 0 2572 1757 10 10 7;8 12;14 90 69 Mix4_TiO2_1_1 3553 91 70 Mix4_TiO2_1_3 3844 Q9UID3 Q9UID3 Q9UID3 >sp|Q9UID3|FFR_HUMAN Protein fat-free homolog OS=Homo sapiens GN=FFR PE=1 SV=2 0.499943 0.643364 0.499943 0.643364 9.5108E-09 117.24 0.122794 -8.04131 1.87885E-08 116.39 0.000131531 -38.775 0.000228046 83.625 0.0953629 -6.92154 5.31937E-08 113.25 1 S AAAAGPSPGSGPG Proline-directed 0.05 9.5108E-09 117.24 _(ac)AAAAAAGPpSPGSGPGDSPEGPEGEAPER_ AAAAAAGPS(0.5)PGS(0.431)GPGDS(0.069)PEGPEGEAPER AAAAAAGPS(0.64)PGS(-0.64)GPGDS(-8.6)PEGPEGEAPER 9 3 871.03632 1.0851 21895 0.0045716 21895 0 0 0 0 0 0 2573 1757 13 13 7;8 12;14 94 73 Mix4_TiO2_Reinj_1_1 3970 91 70 Mix4_TiO2_1_3 3844 Q9UID3 Q9UID3 Q9UID3 >sp|Q9UID3|FFR_HUMAN Protein fat-free homolog OS=Homo sapiens GN=FFR PE=1 SV=2 0.782185 8.04131 0.431106 -0.643364 9.5108E-09 117.24 0.782185 8.04131 1.87885E-08 116.39 0.00783817 -21.0231 0.000228046 83.625 0.46939 0.327971 5.31937E-08 113.25 1 S AGPSPGSGPGDSP CK1 0.081 9.5108E-09 117.24 _(ac)AAAAAAGPSPGpSGPGDSPEGPEGEAPER_ AAAAAAGPS(0.123)PGS(0.782)GPGDS(0.095)PEGPEGEAPER AAAAAAGPS(-8.04)PGS(8.04)GPGDS(-9.15)PEGPEGEAPER 12 3 871.03632 0.3809 96670 0.020184 0 0 0 96670 0 0 0 2574 1757 18 18 7;8 12;14 88 67 Mix4_InSol_Tio2_Reinj_1 4610 91 70 Mix4_TiO2_1_3 3844 Q9UID3 Q9UID3 Q9UID3 >sp|Q9UID3|FFR_HUMAN Protein fat-free homolog OS=Homo sapiens GN=FFR PE=1 SV=2 0.999588 33.9396 0.99928 31.5827 9.5108E-09 117.24 0.996713 24.9224 1.87885E-08 116.39 0.99203 21.0231 0.000228046 83.625 0.999588 33.9396 5.31937E-08 113.25 1 S GSGPGDSPEGPEG Proline-directed 0.05 9.5108E-09 117.24 _(ac)AAAAAAGPSPGSGPGDpSPEGPEGEAPER_ AAAAAAGPSPGSGPGDS(1)PEGPEGEAPER AAAAAAGPS(-50.7)PGS(-33.94)GPGDS(33.94)PEGPEGEAPER 17 3 871.03632 -0.05371 7677700 1.603 1819100 0 0 5412400 0 201140 245090 2575 1757 652 652 5987 6827 59142 35925 Mix4_TiO2_Reinj_1_3 4882 59142 35925 Mix4_TiO2_Reinj_1_3 4882 Q9UID3;Q9UID3-2 Q9UID3 Q9UID3 >sp|Q9UID3|FFR_HUMAN Protein fat-free homolog OS=Homo sapiens GN=FFR PE=1 SV=2;>sp|Q9UID3-2|FFR_HUMAN Isoform 2 of Protein fat-free homolog OS=Homo sapiens GN=FFR 0.830447 10.0756 0 0 0.830447 10.0756 0.0283138 53.921 1 S RTFSVYSSSRQQG CK1 0.081 0.0283138 53.921 _TFSVYpSSSR_ TFSVY(0.006)S(0.83)S(0.082)S(0.082)R T(-53.92)FS(-53.92)VY(-21.18)S(10.08)S(-10.08)S(-10.08)R 6 2 557.23425 0.79466 68281 0 0 0 68281 0 0 0 2576 1758 1468 1468 3294 3729 31118 19283 Mix4_TiO2_Reinj_1_5 3759 31118 19283 Mix4_TiO2_Reinj_1_5 3759 Q9UIG0;Q9UIG0-2 Q9UIG0 Q9UIG0 >sp|Q9UIG0|BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B OS=Homo sapiens GN=BAZ1B PE=1 SV=2;>sp|Q9UIG0-2|BAZ1B_HUMAN Isoform 2 of Tyrosine-protein kinase BAZ1B OS=Homo sapiens GN=BAZ1B 1 172.238 1 130.134 2.65435E-09 130.13 0 0 1 172.238 2.1903E-20 185.16 1 S AEDEGDSEPEAVG CK2 0.117 2.1903E-20 185.16 _LAEDEGDpSEPEAVGQSR_ LAEDEGDS(1)EPEAVGQSR LAEDEGDS(172.24)EPEAVGQS(-172.24)R 8 2 934.88092 -0.23707 347850 125710 0 0 222140 0 0 0 2577 1759 349 349 3948 4497 37430 23010 Mix4_TiO2_Reinj_1_4 3715 37430 23010 Mix4_TiO2_Reinj_1_4 3715 Q9UIK4 Q9UIK4 Q9UIK4 >sp|Q9UIK4|DAPK2_HUMAN Death-associated protein kinase 2 OS=Homo sapiens GN=DAPK2 PE=1 SV=1 0.952899 13.0602 0 0 0.952899 13.0602 1.74236E-08 161.4 1 S DLRNCESDTEEDI CK2 0.117 1.74236E-08 161.4 _NCEpSDTEEDIAR_ NCES(0.953)DT(0.047)EEDIAR NCES(13.06)DT(-13.06)EEDIAR 4 2 759.77434 0.49635 229050 0 0 0 229050 0 0 0 2578 1760 76 76 5435 6186 53025 32411 Mix4_TiO2_Reinj_1_2 5160 53025 32411 Mix4_TiO2_Reinj_1_2 5160 Q9UJ70 Q9UJ70 Q9UJ70 >sp|Q9UJ70|NAGK_HUMAN N-acetyl-D-glucosamine kinase OS=Homo sapiens GN=NAGK PE=1 SV=4 0.999978 46.6361 0 0 0.999978 46.6361 0.0021766 81.872 0 0 1 S SLGLSLSGGDQED CK2;NEK6 0.076 0.0021766 81.872 _SLGLSLpSGGDQEDAGR_ SLGLSLS(1)GGDQEDAGR S(-63.67)LGLS(-46.64)LS(46.64)GGDQEDAGR 7 2 821.35943 -0.25148 28222 0 0 0 28222 0 0 0 2579 1762 588 588 5069;6604 5763;5764;7559 49018 29955 Mix4_TiO2_1_4 6103 49020 29959 Mix4_TiO2_Reinj_1_3 6983 Q9UJX2;Q9UJX2-3 Q9UJX2 Q9UJX2 >sp|Q9UJX2|CDC23_HUMAN Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 PE=1 SV=3;>sp|Q9UJX2-3|CDC23_HUMAN Isoform 3 of Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 0.999998 57.0747 0.999998 57.0747 0.00102561 101.08 0.925113 15.6891 0.460969 15.689 0.999439 32.5121 0.000767824 105.96 0.995809 23.8818 0.0566967 49.052 0.999991 50.3294 0.0041987 87.847 1 S TPTRRVSPLNLSS CAMK2;CK1;PKA;Proline-directed 0.004788 0.000767824 105.96 _RVpSPLNLSSVTP_ RVS(1)PLNLSSVTP RVS(57.07)PLNLS(-57.07)S(-91.79)VT(-101.08)P 3 2 675.34487 -0.033799 2613100 540030 30291 0 1662300 0 205300 175210 2580 1764 221 221 4466;4467 5077;5078 42406 26084 Mix4_TiO2_1_3 7368 42406 26084 Mix4_TiO2_1_3 7368 Q9UJX4;Q9UJX4-2 Q9UJX4 Q9UJX4 >sp|Q9UJX4|APC5_HUMAN Anaphase-promoting complex subunit 5 OS=Homo sapiens GN=ANAPC5 PE=1 SV=2;>sp|Q9UJX4-2|APC5_HUMAN Isoform 2 of Anaphase-promoting complex subunit 5 OS=Homo sapiens GN=ANAPC5 0.999932 41.6657 0.999932 41.6657 0.00184201 89.035 0.985913 18.5596 0.23051 39.594 1 S FLSQQASLLKNDE CK1 0.143 0.00184201 89.035 _QAEFFLSQQApSLLK_ QAEFFLSQQAS(1)LLK QAEFFLS(-41.67)QQAS(41.67)LLK 11 2 845.41602 0.080767 369950 119510 0 0 250430 0 0 0 2581 1765 777 777 2811 3203 26902 16814 Mix4_TiO2_Reinj_1_3 7402 26902 16814 Mix4_TiO2_Reinj_1_3 7402 Q9UJX5 Q9UJX5 Q9UJX5 >sp|Q9UJX5|APC4_HUMAN Anaphase-promoting complex subunit 4 OS=Homo sapiens GN=ANAPC4 PE=1 SV=2 0.5 0 0.5 0 0.00788452 75.099 1 S IKEEVLSESEAEN CK2 0.117 0.00788452 75.099 _IKEEVLpSESEAENQQAGAAALAPEIVIK_ IKEEVLS(0.5)ES(0.5)EAENQQAGAAALAPEIVIK IKEEVLS(0)ES(0)EAENQQAGAAALAPEIVIK 7 3 1006.5075 0.5687 885160 0 0 0 885160 0 0 0 2582 1765 779 779 2811 3203 26902 16814 Mix4_TiO2_Reinj_1_3 7402 26902 16814 Mix4_TiO2_Reinj_1_3 7402 Q9UJX5 Q9UJX5 Q9UJX5 >sp|Q9UJX5|APC4_HUMAN Anaphase-promoting complex subunit 4 OS=Homo sapiens GN=ANAPC4 PE=1 SV=2 0.5 0 0.5 0 0.00788452 75.099 1 S EEVLSESEAENQQ CK2;NEK6 0.076 0.00788452 75.099 _IKEEVLpSESEAENQQAGAAALAPEIVIK_ IKEEVLS(0.5)ES(0.5)EAENQQAGAAALAPEIVIK IKEEVLS(0)ES(0)EAENQQAGAAALAPEIVIK 9 3 1006.5075 0.5687 885160 0 0 0 885160 0 0 0 2583 1767 389 389 2192 2481 20123 12390 Mix4_TiO2_Reinj_1_5 8716 20122 12388 Mix4_TiO2_Reinj_1_3 8911 Q9UK32 Q9UK32 Q9UK32 >sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Homo sapiens GN=RPS6KA6 PE=1 SV=1 1 78.2758 1 78.2689 8.42029E-16 185.04 0 0 1 78.2758 8.42021E-16 185.04 1 S QLFKGFSFVATSI CHK1;PDK1;PKD 0.0001168 8.42021E-16 185.04 _GFpSFVATSIAEEYK_ GFS(1)FVATSIAEEYK GFS(78.28)FVAT(-79.42)S(-78.28)IAEEY(-104.04)K 3 2 814.86583 0.666 866570 215220 0 0 651350 0 0 0 2584 1769 1103 1103 2224 2517 20433 12541 Mix4_InSol_TiO2_1 4015 20434 12542 Mix4_TiO2_Reinj_1_5 3793 Q9UK61;Q9UK61-4;Q9UK61-3;Q9UK61-2 Q9UK61 Q9UK61 >sp|Q9UK61|CC063_HUMAN Uncharacterized protein C3orf63 OS=Homo sapiens GN=C3orf63 PE=1 SV=3;>sp|Q9UK61-4|CC063_HUMAN Isoform 4 of Uncharacterized protein C3orf63 OS=Homo sapiens GN=C3orf63;>sp|Q9UK61-3|CC063_HUMAN Isoform 3 of Uncharacterized protein C3orf 0.996556 24.6142 0 0 0 0 0.984192 17.9419 0.00224323 84.231 0.996556 24.6142 0.00989334 73.423 0 0 1 S GNLPPVSPNDSGA CK2;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.00224323 84.231 _GGNLPPVpSPNDSGAK_ GGNLPPVS(0.997)PNDS(0.003)GAK GGNLPPVS(24.61)PNDS(-24.61)GAK 8 2 745.33777 -0.46181 82932 0 0 0 64744 0 18187 0 2585 1771 448 448 1459 1641 13681 8356 Mix4_TiO2_Reinj_1_1 6130 13681 8356 Mix4_TiO2_Reinj_1_1 6130 Q9UKA4 Q9UKA4 Q9UKA4 >sp|Q9UKA4|AKA11_HUMAN A-kinase anchor protein 11 OS=Homo sapiens GN=AKAP11 PE=1 SV=1 0.999478 32.8227 0.995374 23.3279 0.18009 31.436 0.999478 32.8227 0.00690366 60.566 1 S EDSGLFSPIRSSA CDK1;CDK2;CK1;F box bTrCP;GSK3;Proline-directed 0.000624338 0.00690366 60.566 _EDSGLFpSPIR_ EDS(0.001)GLFS(0.999)PIR EDS(-32.82)GLFS(32.82)PIR 7 2 600.76846 0.080444 106560 23256 0 0 83304 0 0 0 2586 1771 1171 1171 5469 6225 53350 32596 Mix4_TiO2_Reinj_1_1 6472 53350 32596 Mix4_TiO2_Reinj_1_1 6472 Q9UKA4 Q9UKA4 Q9UKA4 >sp|Q9UKA4|AKA11_HUMAN A-kinase anchor protein 11 OS=Homo sapiens GN=AKAP11 PE=1 SV=1 0.579942 1.40075 0 0 0 0 0.579942 1.40075 4.28579E-11 133.66 0 0 1 S KLMRSLSEEVESS CAMK2;CHK1;CHK1/2;PKD 0.003192 4.28579E-11 133.66 _SLpSEEVESSESGELPEVDVK_ S(0.42)LS(0.58)EEVESSESGELPEVDVK S(-1.4)LS(1.4)EEVES(-79.82)S(-86.43)ES(-92.88)GELPEVDVK 3 2 1114.9883 -0.29616 122900 0 0 0 122900 0 0 0 2587 1771 1242 1242 5849 6669 57678 35097 Mix4_TiO2_1_1 5284 57679 35098 Mix4_TiO2_Reinj_1_1 6015 Q9UKA4 Q9UKA4 Q9UKA4 >sp|Q9UKA4|AKA11_HUMAN A-kinase anchor protein 11 OS=Homo sapiens GN=AKAP11 PE=1 SV=1 0.98608 21.0144 0.98608 21.0144 0.0337631 58.647 0 0 0.905102 9.79734 5.26E-05 107.38 0 0 0.32627 -1.03937 0.513254 25.513 1 S QSQRSVSPTFLNP CAMK2;PKA/AKT;Proline-directed 0.00111111 5.26E-05 107.38 _SVpSPTFLNPSDENLK_ S(0.008)VS(0.986)PT(0.006)FLNPSDENLK S(-21.01)VS(21.01)PT(-22.08)FLNPS(-58.65)DENLK 3 2 864.39802 0.95437 452750 86078 0 0 366670 0 0 0 2588 1772 764 764 385;6577 441;7527 3678 2191 Mix4_TiO2_1_5 3217 3678 2191 Mix4_TiO2_1_5 3217 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.998977 29.8974 0.998977 29.8974 2.14539E-06 114.03 0.990843 20.2417 0.00149144 84.636 0.897833 9.3895 0.0337924 58.622 0.635351 0.576005 1.43818 7.2377 2 S TRVRANSKSEGSP CAMK2;CK2;PKA/AKT 0.001764 2.14539E-06 114.03 _ANpSKSEGpSPVLPHEPAK_ ANS(0.999)KS(0.001)EGS(1)PVLPHEPAK ANS(29.9)KS(-29.9)EGS(35.44)PVLPHEPAK 3 2 954.41864 -0.22375 878830 68849 0 0 512420 0 212520 85049 2589 1772 766 766 385;5216;6577 441;5938;7527 50572 30979 Mix4_InSol_TiO2_1 4334 50581 30990 Mix4_TiO2_Reinj_1_5 4053 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.892498 9.19191 0.988934 19.4052 2.14539E-06 114.03 0.951691 12.9004 0.00149144 84.636 0.892498 9.19191 0.0388722 55.369 0.781016 2.79064 1.43818 7.2377 1 S VRANSKSEGSPVL 0.000588558 99.62 _pSEGSPVLPHEPAK_ S(0.892)EGS(0.108)PVLPHEPAK S(9.19)EGS(-9.19)PVLPHEPAK 1 2 714.33196 0.30601 75206 0 0 0 0 0 75206 0 2590 1772 769 769 385;5216;6577 441;5938;7527 50578 30986 Mix4_TiO2_Reinj_1_1 3511 50581 30990 Mix4_TiO2_Reinj_1_5 4053 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.999989 49.5075 0.997465 25.9492 0.00150401 94.627 0.999989 49.5075 0.000588558 99.62 0.841155 7.23901 0.0388722 55.369 0.912365 10.1749 0.172549 35.926 1 S NSKSEGSPVLPHE CK1;Proline-directed 0.05 0.000588558 99.62 _SEGpSPVLPHEPAK_ SEGS(1)PVLPHEPAK S(-49.51)EGS(49.51)PVLPHEPAK 4 2 714.33196 -0.16806 850600 181190 0 0 582530 0 13799 73084 2591 1772 707 707 3463;3464 3909;3910 32605 20225 Mix4_TiO2_1_1 3480 32601 20221 Mix4_InSol_TiO2_1 4809 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.999995 52.998 0.999995 52.998 0.00420552 78.772 0.979149 16.7173 0.272973 32.535 0.999935 41.8715 0.101093 41.871 0 0 0.999987 48.8115 0.001669 90.079 0.999867 38.7584 0.0739686 48.314 1 S SQPIRASNPDLRR CK2;PKA 0.042 0.001669 90.079 _LGSQPIRApSNPDLR_ LGSQPIRAS(1)NPDLR LGS(-53)QPIRAS(53)NPDLR 9 3 535.26992 0.11007 5823100 546910 57262 0 3113300 0 1283300 822320 2592 1772 640 640 4666 5295 44207 27072 Mix4_TiO2_Reinj_1_5 4275 44205 27070 Mix4_TiO2_1_5 3563 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.999998 56.9841 0.999987 49.4155 0.00020188 98.071 0 0 0.999998 56.9841 0.000269191 97.639 1 S EMPRQNSDPTSEN CAMK2;CHK1;GSK3 0.0228 0.00020188 98.071 _QNpSDPTSENPPLPTR_ QNS(1)DPTSENPPLPTR QNS(56.98)DPT(-56.98)S(-64.13)ENPPLPT(-97.64)R 3 2 866.88053 0.85274 485410 135420 0 0 349980 0 0 0 2593 1772 547 547 4743 5389 45258 27692 Mix4_InSol_TiO2_1 2457 45258 27692 Mix4_InSol_TiO2_1 2457 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.5 0 0 0 0 0 0 0 0.5 0 0.0953497 39.092 0.129662 -8.26876 0.338897 21.72 1 S SRLNRQSSPAMPH PKA 0.042 0.0953497 39.092 _QpSSPAMPHK_ QS(0.5)S(0.5)PAMPHK QS(0)S(0)PAMPHK 2 2 531.72554 0.92297 211980 0 0 0 0 0 211980 0 2594 1772 548 548 4743 5389 45259 27693 Mix4_InSol_Tio2_Reinj_1 2493 45258 27692 Mix4_InSol_TiO2_1 2457 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.870338 8.26876 0 0 0 0 0 0 0.5 0 0.0953497 39.092 0.870338 8.26876 0.338897 21.72 1 S RLNRQSSPAMPHK CAMK2;CHK1;CHK1/2;PKD;Polo box;Proline-directed 0.003192 0.0953497 39.092 _QSpSPAMPHK_ QS(0.13)S(0.87)PAMPHK QS(-8.27)S(8.27)PAMPHK 3 2 531.72554 0.90748 424960 0 0 0 0 0 211980 212970 2595 1772 680 680 6266 7158 62454 37995 Mix4_TiO2_Reinj_1_5 4441 62453 37994 Mix4_TiO2_Reinj_1_1 3946 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 1 65.8859 0.99993 41.5426 0.000803285 80.378 0.999607 34.1739 0.00946841 59.421 1 65.8859 0.00157267 94.95 0.785698 9.62377 0.548014 10.87 0.999877 39.1153 0.00264447 73.7 0.99997 46.0014 0.00357427 70.833 1 S QRTTSISPALARK CK1;Proline-directed 0.05 0.00157267 94.95 _TTSIpSPALAR_ TTSIS(1)PALAR T(-82.67)T(-85.88)S(-65.89)IS(65.89)PALAR 5 2 548.77355 0.11375 4738200 340810 99274 0 2486200 17741 838930 955240 2596 1772 560 560 6339 7248 63883 39137 Mix4_TiO2_Reinj_1_5 4372 63883 39137 Mix4_TiO2_Reinj_1_5 4372 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 1 59.4869 0 0 1 59.4869 0.0237161 59.487 1 S KVANRISDPNLPP PKA 0.042 0.0237161 59.487 _VANRIpSDPNLPPR_ VANRIS(1)DPNLPPR VANRIS(59.49)DPNLPPR 6 3 510.25924 0.38733 50211 0 0 0 50211 0 0 0 2597 1773 135 135 2410 2731 22523 14065 Mix4_TiO2_Reinj_1_4 4632 22523 14065 Mix4_TiO2_Reinj_1_4 4632 Q9UKM9;Q9UKM9-2 Q9UKM9 Q9UKM9 >sp|Q9UKM9|RALY_HUMAN RNA-binding protein Raly OS=Homo sapiens GN=RALY PE=1 SV=1;>sp|Q9UKM9-2|RALY_HUMAN Isoform 1 of RNA-binding protein Raly OS=Homo sapiens GN=RALY 1 63.869 1 37.472 0.00639672 62.129 1 45.58 0.0512717 45.58 1 63.869 0.00583245 63.869 0 0 1 36.1258 0.105843 37.588 1 36.1258 0.0698094 40.574 1 S DYRGRLSPVPVPR PKA;Proline-directed 0.042 0.00583245 63.869 _GRLpSPVPVPR_ GRLS(1)PVPVPR GRLS(63.87)PVPVPR 4 2 579.31317 -0.078325 26752000 3449800 359740 0 15611000 0 3802400 3528700 2598 1773 288 288 6192 7071;7073 61304 37131 Mix4_TiO2_Reinj_1_4 5640 61302 37129 Mix4_TiO2_1_4 5181 Q9UKM9;Q9UKM9-2 Q9UKM9 Q9UKM9 >sp|Q9UKM9|RALY_HUMAN RNA-binding protein Raly OS=Homo sapiens GN=RALY PE=1 SV=1;>sp|Q9UKM9-2|RALY_HUMAN Isoform 1 of RNA-binding protein Raly OS=Homo sapiens GN=RALY 0.949676 13.1076 0.401455 -1.7339 7.82364E-13 129.47 0.949676 13.1076 0.00025746 86.522 0.357784 -0.425943 1.78808 24.797 0 0 1 S EGLLTHSEEELEH CK2;NEK6 0.076 7.82364E-13 129.47 _TRDDGDEEGLLTHpSEEELEHSQDTDADDGALQ_ TRDDGDEEGLLT(0.046)HS(0.95)EEELEHS(0.004)QDTDADDGALQ T(-52.76)RDDGDEEGLLT(-13.11)HS(13.11)EEELEHS(-24.21)QDT(-35.22)DADDGALQ 14 3 1203.1536 0.028296 10102000 1.7919 0 0 0 10102000 0 0 0 2599 1775 542 542 6531 7474 65979 40453 Mix4_TiO2_Reinj_1_1 4897 65979 40453 Mix4_TiO2_Reinj_1_1 4897 Q9UKV5 Q9UKV5 Q9UKV5 >sp|Q9UKV5|AMFR2_HUMAN E3 ubiquitin-protein ligase AMFR OS=Homo sapiens GN=AMFR PE=1 SV=2 1 61.9949 1 12.8659 0.517493 12.866 1 61.9949 0.024653 61.995 1 S RVPLDLSPRLEET CDK1;NEK6;Proline-directed 0.0057 0.024653 61.995 _VPLDLpSPR_ VPLDLS(1)PR VPLDLS(61.99)PR 6 2 488.7468 0.2211 33044 6852.7 0 0 26191 0 0 0 2600 1776 41 41 1293 1458 12129 7433 Mix4_TiO2_Reinj_1_5 3326 12129 7433 Mix4_TiO2_Reinj_1_5 3326 Q9UKY4 Q9UKY4 Q9UKY4 >sp|Q9UKY4|POMT2_HUMAN Protein O-mannosyl-transferase 2 OS=Homo sapiens GN=POMT2 PE=1 SV=2 1 65.6442 1 8.34945 0.629838 8.3494 1 65.6442 0.0142009 65.644 0 0 1 S AEAVARSPKRPAW CDK1;CDK2;Proline-directed 0.0057 0.0142009 65.644 _DVAAEAVARpSPK_ DVAAEAVARS(1)PK DVAAEAVARS(65.64)PK 10 2 647.31357 0.44248 90918 19134 0 0 71784 0 0 0 2601 1778 827 827 2826 3218 26979 16858 Mix4_TiO2_1_5 3409 26979 16858 Mix4_TiO2_1_5 3409 Q9UL54;Q9UL54-3 Q9UL54 Q9UL54 >sp|Q9UL54|TAOK2_HUMAN Serine/threonine-protein kinase TAO2 OS=Homo sapiens GN=TAOK2 PE=1 SV=2;>sp|Q9UL54-3|TAOK2_HUMAN Isoform 3 of Serine/threonine-protein kinase TAO2 OS=Homo sapiens GN=TAOK2 0.999063 30.2853 0.999063 30.2853 0.0133056 70.432 0 0 0 0 1 S SGAPSPSPQKHGS CDK1;CDK2;Proline-directed 0.0057 0.0133056 70.432 _ILGEESGAPSPpSPQK_ ILGEESGAPS(0.001)PS(0.999)PQK ILGEES(-57.37)GAPS(-30.29)PS(30.29)PQK 12 2 788.86636 0.063331 45582 45582 0 0 0 0 0 0 2602 1779 28 28 3138 3563 29813 18562 Mix4_TiO2_1_3 4012 29813 18562 Mix4_TiO2_1_3 4012 Q9ULC5-3 Q9ULC5-3 Q9ULC5-3 >sp|Q9ULC5-3|ACSL5_HUMAN Isoform ACSL5a of Long-chain-fatty-acid--CoA ligase 5 OS=Homo sapiens GN=ACSL5 0.999907 40.3235 0.999907 40.3235 0.00602693 76.811 0.899267 12.5175 0.924811 12.517 0 0 0 0 1 S SCGRKNSEPGSPH CAMK2;GSK3;PKA 0.004788 0.00602693 76.811 _KNpSEPGSPHSLEALR_ KNS(1)EPGSPHSLEALR KNS(40.32)EPGS(-40.32)PHS(-72.17)LEALR 3 3 567.93671 -0.014528 639520 89335 0 0 550190 0 0 0 2603 1780 929 929 5180 5897 50152 30654 Mix4_TiO2_1_5 2402 50152 30654 Mix4_TiO2_1_5 2402 Q9ULE0 Q9ULE0 Q9ULE0 >sp|Q9ULE0|WWC3_HUMAN Protein WWC3 OS=Homo sapiens GN=WWC3 PE=2 SV=3 0.332342 0 0.332342 0 0.027654 53.4 0 0 1 S YRSDSDSSTLPRK CK1 0.143 0.027654 53.4 _SDSDpSSTLPR_ SDS(0.003)DS(0.332)S(0.332)T(0.332)LPR S(-48.73)DS(-20.49)DS(0)S(0)T(0)LPR 5 2 572.72953 0.027209 0 0 0 0 0 0 0 0 2604 1780 930 930 5180 5897 50152 30654 Mix4_TiO2_1_5 2402 50152 30654 Mix4_TiO2_1_5 2402 Q9ULE0 Q9ULE0 Q9ULE0 >sp|Q9ULE0|WWC3_HUMAN Protein WWC3 OS=Homo sapiens GN=WWC3 PE=2 SV=3 0.332342 0 0.332342 0 0.027654 53.4 0 0 1 S RSDSDSSTLPRKS CK1 0.081 0.027654 53.4 _SDSDpSSTLPR_ SDS(0.003)DS(0.332)S(0.332)T(0.332)LPR S(-48.73)DS(-20.49)DS(0)S(0)T(0)LPR 6 2 572.72953 0.027209 0 0 0 0 0 0 0 0 2605 1781 1555 1555 6529 7472 65956 40448 Mix4_TiO2_Reinj_1_5 3134 65955 40447 Mix4_TiO2_Reinj_1_5 3110 Q9ULH0;Q9ULH0-4;Q9ULH0-2;Q9ULH0-5 Q9ULH0 Q9ULH0 >sp|Q9ULH0|KDIS_HUMAN Kinase D-interacting substrate of 220 kDa OS=Homo sapiens GN=KIDINS220 PE=1 SV=3;>sp|Q9ULH0-4|KDIS_HUMAN Isoform 4 of Kinase D-interacting substrate of 220 kDa OS=Homo sapiens GN=KIDINS220;>sp|Q9ULH0-2|KDIS_HUMAN Isoform 2 of Kinase D 0.999079 30.3552 0.279872 -4.10451 0.0914653 41.078 0 0 0.999079 30.3552 0.00408845 82.527 0.951501 12.9268 0.259132 30.553 0.963888 14.2638 0.223335 32.761 1 S VERVPKSPEHSAE ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.00408845 82.527 _VPKpSPEHSAEPIR_ VPKS(0.999)PEHS(0.001)AEPIR VPKS(30.36)PEHS(-30.36)AEPIR 4 3 509.58361 0.14549 1278400 0 0 0 983560 0 99277 195540 2606 1781 1559 1559 6529 7472 65950 40442 Mix4_InSol_TiO2_2 2511 65955 40447 Mix4_TiO2_Reinj_1_5 3110 Q9ULH0;Q9ULH0-4;Q9ULH0-2;Q9ULH0-5 Q9ULH0 Q9ULH0 >sp|Q9ULH0|KDIS_HUMAN Kinase D-interacting substrate of 220 kDa OS=Homo sapiens GN=KIDINS220 PE=1 SV=3;>sp|Q9ULH0-4|KDIS_HUMAN Isoform 4 of Kinase D-interacting substrate of 220 kDa OS=Homo sapiens GN=KIDINS220;>sp|Q9ULH0-2|KDIS_HUMAN Isoform 2 of Kinase D 0.820039 6.58656 0.720128 4.10451 0.0914653 41.078 0 0 0.811644 6.34386 0.00408845 82.527 0.820039 6.58656 0.259132 30.553 0.0639497 -11.6546 0.223335 32.761 1 S PKSPEHSAEPIRT CK1 0.143 0.00408845 82.527 _VPKSPEHpSAEPIR_ VPKS(0.18)PEHS(0.82)AEPIR VPKS(-6.59)PEHS(6.59)AEPIR 8 2 763.87178 0.5479 229920 22262 0 0 195370 0 12282 0 2607 1784 216 216 1991;4096 2251;4665 38748 23768 Mix4_TiO2_Reinj_1_4 4909 38746 23766 Mix4_InSol_TiO2_1 5470 Q9ULS5;O75069 Q9ULS5 Q9ULS5 >sp|Q9ULS5|TMCC3_HUMAN Transmembrane and coiled-coil domains protein 3 OS=Homo sapiens GN=TMCC3 PE=2 SV=3;>sp|O75069|TMCC2_HUMAN Transmembrane and coiled-coil domains protein 2 OS=Homo sapiens GN=TMCC2 PE=2 SV=3 1 36.3932 1 3.79904 0.00908975 64.659 0 0 0 0 1 36.3932 0.0403937 51.484 1 86.9049 0.00315338 86.905 1 38.9558 0.123952 38.956 1 S IRNKFGSADNIAH 0.00315338 86.905 _NKFGpSADNIAHLK_ NKFGS(1)ADNIAHLK NKFGS(36.39)ADNIAHLK 5 3 498.90821 -0.39254 1872600 227080 0 0 1117500 0 396440 131590 2608 1784 4 4 4417 5025 42067 25921 Mix4_TiO2_Reinj_1_4 4014 42067 25921 Mix4_TiO2_Reinj_1_4 4014 Q9ULS5 Q9ULS5 Q9ULS5 >sp|Q9ULS5|TMCC3_HUMAN Transmembrane and coiled-coil domains protein 3 OS=Homo sapiens GN=TMCC3 PE=2 SV=3 0.991587 20.7169 0 0 0 0 0.991587 20.7169 0.0309584 54.283 0 0 0 0 1 S ___MPGSDTALTV 0.0309584 54.283 _PGpSDTALTVDR_ PGS(0.992)DT(0.008)ALTVDR PGS(20.72)DT(-20.72)ALT(-52.26)VDR 3 2 606.26882 0.1865 102850 0 0 0 102850 0 0 0 2609 1786 738 738 5691 6482 55729 34153 Mix4_InSol_Tio2_Reinj_1 5369 55733 34160 Mix4_TiO2_Reinj_1_3 5146 Q9ULW0 Q9ULW0 Q9ULW0 >sp|Q9ULW0|TPX2_HUMAN Targeting protein for Xklp2 OS=Homo sapiens GN=TPX2 PE=1 SV=2 1 66.9079 0.999925 41.2453 0.00112217 96.415 0 0 0.999965 44.5493 5.2859E-06 138.28 0.999987 48.9076 0.00217884 91.468 1 66.9079 0.00338835 85.805 1 S PLTVPVSPKFSTR CDK1;CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 5.2859E-06 138.28 _SSDQPLTVPVpSPK_ SSDQPLTVPVS(1)PK S(-85.8)S(-85.8)DQPLT(-66.91)VPVS(66.91)PK 11 2 717.84744 0.35515 2939400 445930 0 0 1693900 0 398650 401010 2610 1789 188 188 4471 5082 42437 26100 Mix4_TiO2_Reinj_1_6 5344 42437 26100 Mix4_TiO2_Reinj_1_6 5344 Q9UM00;Q9UM00-2 Q9UM00 Q9UM00 >sp|Q9UM00|TMCO1_HUMAN Transmembrane and coiled-coil domain-containing protein 1 OS=Homo sapiens GN=TMCO1 PE=1 SV=1;>sp|Q9UM00-2|TMCO1_HUMAN Isoform 2 of Transmembrane and coiled-coil domain-containing protein 1 OS=Homo sapiens GN=TMCO1 0.999621 34.2119 0.930555 11.271 0.432759 31.051 0.999621 34.2119 0.0224547 62.692 1 S PPSGKFS______ CK1 0.143 0.0224547 62.692 _QAGGFLGPPPPSGKFpS_ QAGGFLGPPPPSGKFS(1) QAGGFLGPPPPS(-34.21)GKFS(34.21) 16 2 812.38198 1.1918 71846 20640 0 0 51206 0 0 0 2611 1793 19 19 3428 3872 32185 19890 Mix4_TiO2_Reinj_1_2 3304 32185 19890 Mix4_TiO2_Reinj_1_2 3304 Q9UNE7 Q9UNE7 Q9UNE7 >sp|Q9UNE7|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP OS=Homo sapiens GN=STUB1 PE=1 SV=2 0.999992 50.7897 0.998386 28.3392 0.123479 46.515 0 0 0.999992 50.7897 6.57098E-06 99.659 0 0 0 0 1 S LGAGGGSPEKSPS CDK1;CDK2;GSK3;Proline-directed 0.0057 6.57098E-06 99.659 _LGAGGGpSPEKSPSAQELK_ LGAGGGS(1)PEKSPSAQELK LGAGGGS(50.79)PEKS(-50.79)PS(-80.68)AQELK 7 3 598.28741 0.25913 529730 123260 0 0 406470 0 0 0 2612 1794 247 247 335 378 3073 1865 Mix4_TiO2_1_3 4639 3079 1874 Mix4_TiO2_Reinj_1_4 5390 Q9UNF1;Q9UNF1-2 Q9UNF1 Q9UNF1 >sp|Q9UNF1|MAGD2_HUMAN Melanoma-associated antigen D2 OS=Homo sapiens GN=MAGED2 PE=1 SV=2;>sp|Q9UNF1-2|MAGD2_HUMAN Isoform 2 of Melanoma-associated antigen D2 OS=Homo sapiens GN=MAGED2 0.999952 43.2 0.999952 43.2 0.000698564 79.961 0.997653 26.2855 0.146152 35.468 0.999812 37.2493 0.000888678 82.16 0.960389 13.8463 0.485155 16.789 0.991792 20.8217 0.297685 24.659 1 S ALLSLRSPKARRG CDK1;CK1;Proline-directed 0.0057 0.000888678 82.16 _ALLSLRpSPK_ ALLSLRS(1)PK ALLS(-43.2)LRS(43.2)PK 7 2 532.79682 -0.021411 1801200 319880 47415 0 1105700 0 198930 129310 2613 1794 70 70 563 645 5322 3213 Mix4_TiO2_1_3 1444 5323 3214 Mix4_TiO2_Reinj_1_3 1953 Q9UNF1;Q9UNF1-2 Q9UNF1 Q9UNF1 >sp|Q9UNF1|MAGD2_HUMAN Melanoma-associated antigen D2 OS=Homo sapiens GN=MAGED2 PE=1 SV=2;>sp|Q9UNF1-2|MAGD2_HUMAN Isoform 2 of Melanoma-associated antigen D2 OS=Homo sapiens GN=MAGED2 0.675135 3.17775 0.675135 3.17775 0.0855696 40.125 0 0 0.0219283 -16.4937 0.00326082 78.999 0 0 0.323442 -0.381206 0.736631 0.38121 1 S SKATEVSKTPEAR 0.00326082 78.999 _ATEVpSKTPEAR_ ATEVS(0.675)KT(0.325)PEAR AT(-40.12)EVS(3.18)KT(-3.18)PEAR 5 2 634.79775 -0.84545 29428 29428 0 0 0 0 0 0 2614 1798 1173 1173 4624 5247 43851 26883 Mix4_TiO2_Reinj_1_5 4555 43850 26882 Mix4_TiO2_1_5 3806 Q9UNS1;Q9UNS1-2 Q9UNS1 Q9UNS1 >sp|Q9UNS1|TIM_HUMAN Protein timeless homolog OS=Homo sapiens GN=TIMELESS PE=1 SV=2;>sp|Q9UNS1-2|TIM_HUMAN Isoform 2 of Protein timeless homolog OS=Homo sapiens GN=TIMELESS 1 47.9814 1 133.791 1.34861E-07 133.79 1 47.9814 0.09301 47.981 1 S KRQLLDSDEEQEE CK2;NEK6 0.076 1.34861E-07 133.79 _QLLDpSDEEQEEDEGR_ QLLDS(1)DEEQEEDEGR QLLDS(47.98)DEEQEEDEGR 5 2 936.36256 -0.55843 305860 94024 0 0 211830 0 0 0 2615 1800 197 197 3658 4124 34407 21393 Mix4_TiO2_1_3 3092 34407 21393 Mix4_TiO2_1_3 3092 Q9UP83-2;Q9UP83;Q9UP83-3 Q9UP83-2 Q9UP83-2 >sp|Q9UP83-2|COG5_HUMAN Isoform 2 of Conserved oligomeric Golgi complex subunit 5 OS=Homo sapiens GN=COG5;>sp|Q9UP83|COG5_HUMAN Conserved oligomeric Golgi complex subunit 5 OS=Homo sapiens GN=COG5 PE=1 SV=3;>sp|Q9UP83-3|COG5_HUMAN Isoform 3 of Conserved ol 0.992966 21.4974 0.992966 21.4974 0.00219956 86.876 0 0 0 0 1 S GQLQGGSREITKA 0.00219956 86.876 _LQGQLQGGpSREITK_ LQGQLQGGS(0.993)REIT(0.007)K LQGQLQGGS(21.5)REIT(-21.5)K 9 2 797.90107 0.37107 67344 67344 0 0 0 0 0 0 2616 1801 726 726 2199 2491 20175 12406 Mix4_TiO2_Reinj_1_5 8060 20174 12405 Mix4_TiO2_1_5 7428 Q9UPN7 Q9UPN7 Q9UPN7 >sp|Q9UPN7|PP6R1_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens GN=PPP6R1 PE=1 SV=5 0.522425 1.2881 0.484914 0 0.000681553 90.847 0.522425 1.2881 0.113989 69.088 1 S PTDAPTSPRVSGE CDK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.000681553 90.847 _GGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTpSPR_ GGATPLSYPSPGPQPPGPSWT(0.001)AT(0.001)FDPVPT(0.086)DAPT(0.388)S(0.522)PR GGAT(-60.71)PLS(-54.32)Y(-46.4)PS(-36.98)PGPQPPGPS(-31.31)WT(-25.57)AT(-25.57)FDPVPT(-7.84)DAPT(-1.29)S(1.29)PR 34 3 1228.5733 0.50637 1016400 0 0 0 1016400 0 0 0 2617 1802 1103 1103 5553 6328 54351 33269 Mix4_TiO2_Reinj_1_5 8754 54351 33269 Mix4_TiO2_Reinj_1_5 8754 Q9UPQ0-3;Q9UPQ0;Q9UPQ0-4;Q9UPQ0-2;Q9UPQ0-5;Q9UPQ0-6;Q9UPQ0-8;Q9UPQ0-9 Q9UPQ0-3 Q9UPQ0-3 >sp|Q9UPQ0-3|LIMC1_HUMAN Isoform 3 of LIM and calponin homology domains-containing protein 1 OS=Homo sapiens GN=LIMCH1;>sp|Q9UPQ0|LIMC1_HUMAN LIM and calponin homology domains-containing protein 1 OS=Homo sapiens GN=LIMCH1 PE=1 SV=4;>sp|Q9UPQ0-4|LIMC1_HUMA 0.999999 62.9824 0 0 0.999999 62.9824 6.55055E-06 116.88 1 S KVVKPKSPEPEAT CHK1;ERK/MAPK;PKD;Proline-directed;WW GroupIV 0.0023175 6.55055E-06 116.88 _pSPEPEATLTFPFLDK_ S(1)PEPEATLTFPFLDK S(62.98)PEPEAT(-62.98)LT(-71.16)FPFLDK 1 2 886.41314 0.60795 48552 0 0 0 48552 0 0 0 2618 1803 879 879 797 904 7608 4478 Mix4_TiO2_1_5 4885 7608 4478 Mix4_TiO2_1_5 4885 Q9UPQ9;Q9UPQ9-1 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B 1 67.7589 1 67.7589 4.51301E-34 228.52 0 0 0.999983 47.6994 8.85682E-34 223.45 0 0 1 S SGWEEPSPQSISR Proline-directed 0.05 4.51301E-34 228.52 _DEEPSGWEEPpSPQSISR_ DEEPSGWEEPS(1)PQSISR DEEPS(-109.13)GWEEPS(67.76)PQS(-67.76)IS(-130.08)R 11 2 1005.4098 0.094813 1311600 301330 0 0 1010200 0 0 0 2619 1803 1432 1432 2244;2245 2537;2538;2539 20689 12705 Mix4_TiO2_Reinj_1_1 7812 20689 12705 Mix4_TiO2_Reinj_1_1 7812 Q9UPQ9;Q9UPQ9-1;Q9UPQ9-2 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B;>sp|Q9UPQ9-2|TNR6B_HUMAN Isoform 3 of 0.998579 28.4689 0.980889 17.1035 0.0755298 74.614 0 0 0.998579 28.4689 0.000244466 85.306 0 0 0 0 1 S GKTRGGSPYNQFD CAMK2;CK1;Proline-directed 0.042 0.000244466 85.306 _GGpSPYNQFDIIPGDTLGGHTGPAGDSWLPAK_ GGS(0.999)PY(0.001)NQFDIIPGDTLGGHTGPAGDSWLPAK GGS(28.47)PY(-28.47)NQFDIIPGDT(-82.75)LGGHT(-85.31)GPAGDS(-85.31)WLPAK 3 3 1069.1591 0.46458 2836100 589910 0 0 2246200 0 0 0 2620 1803 1461 1461 2245 2538;2539 20707 12714 Mix4_TiO2_Reinj_1_1 7379 20703 12709 Mix4_TiO2_1_1 6682 Q9UPQ9;Q9UPQ9-1;Q9UPQ9-2 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B;>sp|Q9UPQ9-2|TNR6B_HUMAN Isoform 3 of 0.89622 9.76726 0.861472 11.3213 0.0755298 74.614 0 0 0.89622 9.76726 0.139049 70.281 0 0 0 0 1 S SWLPAKSPPTNKI Proline-directed 0.05 0.0755298 74.614 _GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAKpSPPTNK_ GGSPYNQFDIIPGDT(0.001)LGGHT(0.001)GPAGDS(0.008)WLPAKS(0.896)PPT(0.095)NK GGS(-59.26)PY(-60.38)NQFDIIPGDT(-30.39)LGGHT(-30.39)GPAGDS(-20.73)WLPAKS(9.77)PPT(-9.77)NK 32 4 958.2019 0.7076 5549000 781530 0 0 4767400 0 0 0 2621 1803 1512 1512 2281 2579 21015 12873 Mix4_TiO2_Reinj_1_5 8034 21015 12873 Mix4_TiO2_Reinj_1_5 8034 Q9UPQ9;Q9UPQ9-1;Q9UPQ9-2 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B;>sp|Q9UPQ9-2|TNR6B_HUMAN Isoform 3 of 0.826243 7.70674 0.685073 6.62203 6.56826E-07 105.84 0 0 0.826243 7.70674 1.22972E-11 125.2 0 0 0 0 1 S LGGTATSPIVDTD Proline-directed 0.05 1.22972E-11 125.2 _GIQNIDPESDPYVTPGSVLGGTATpSPIVDTDHQLLR_ GIQNIDPESDPYVTPGSVLGGT(0.025)AT(0.14)S(0.826)PIVDT(0.009)DHQLLR GIQNIDPES(-80.23)DPY(-67.08)VT(-54.11)PGS(-35.41)VLGGT(-15.23)AT(-7.71)S(7.71)PIVDT(-19.81)DHQLLR 25 3 1281.621 0.19177 2553000 165990 0 0 2387000 0 0 0 2622 1803 1011 1011 2635 2998 24602 15247 Mix4_TiO2_Reinj_1_5 6028 24602 15247 Mix4_TiO2_Reinj_1_5 6028 Q9UPQ9;Q9UPQ9-1;Q9UPQ9-2 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B;>sp|Q9UPQ9-2|TNR6B_HUMAN Isoform 3 of 0.999641 35.8815 0 0 0.999641 35.8815 0.0835729 66.965 1 S TGARHPSWEEEED CAMK2;CK2 0.042 0.0835729 66.965 _HPpSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGK_ HPS(1)WEEEEDGGVWNTTGSQGSASSHNSASWGQGGK HPS(35.88)WEEEEDGGVWNT(-35.88)T(-46.59)GS(-49.45)QGS(-52.29)AS(-46.1)S(-46.1)HNS(-51.13)AS(-52.91)WGQGGK 3 3 1241.8383 -0.31151 504110 0 0 0 504110 0 0 0 2623 1803 1816 1816 3864 4379;4380 36663 22598 Mix4_TiO2_Reinj_1_5 8784 36663 22598 Mix4_TiO2_Reinj_1_5 8784 Q9UPQ9;Q9UPQ9-1;Q9UPQ9-2 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B;>sp|Q9UPQ9-2|TNR6B_HUMAN Isoform 3 of 1 126.097 1 99.8744 1.8256E-06 99.874 0.997683 29.3501 0.691656 29.35 1 126.097 1.29568E-10 126.1 0 0 0.792785 8.83764 1.50156 8.8376 1 S DPHRMGSPAPLLP CAMK2;Proline-directed 0.042 1.29568E-10 126.1 _M(ox)GpSPAPLLPGDLLGGGSDSI_ MGS(1)PAPLLPGDLLGGGSDSI MGS(126.1)PAPLLPGDLLGGGS(-126.1)DS(-126.1)I 3 2 975.44993 0.023622 1245900 291330 8242.2 0 915400 0 0 30884 2624 1803 567 567 5757 6560 56604 34548 Mix4_TiO2_Reinj_1_5 1841 56604 34548 Mix4_TiO2_Reinj_1_5 1841 Q9UPQ9;Q9UPQ9-1 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B 0.994667 23.6825 0 0 0.994667 23.6825 0.000228565 94.995 0.105367 -1.7338 1.61997 1.7338 0 0 1 S SSSSTGSEVGGQS CK1 0.081 0.000228565 94.995 _SSSSTGpSEVGGQSTGSNHK_ SSSS(0.001)T(0.004)GS(0.995)EVGGQSTGSNHK S(-46.92)S(-39.04)S(-39.04)S(-30.92)T(-23.68)GS(23.68)EVGGQS(-72.98)T(-78.63)GS(-84.11)NHK 7 2 937.38162 0.80886 37742 0 0 0 37742 0 0 0 2625 1803 573 573 5757 6560 56603 34547 Mix4_InSol_TiO2_1 1920 56604 34548 Mix4_TiO2_Reinj_1_5 1841 Q9UPQ9;Q9UPQ9-1 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B 0.157066 1.7338 0 0 5.01069E-08 -72.9778 0.000228565 94.995 0.157066 1.7338 1.61997 1.7338 0 0 1 S SEVGGQSTGSNHK 0.000228565 94.995 _SSSSTGSEVGGQpSTGSNHK_ S(0.105)S(0.105)S(0.105)S(0.105)T(0.105)GS(0.105)EVGGQS(0.157)T(0.105)GS(0.105)NHK S(-1.73)S(-1.73)S(-1.73)S(-1.73)T(-1.73)GS(-1.73)EVGGQS(1.73)T(-1.73)GS(-1.73)NHK 13 2 937.38162 0.161 0 0 0 0 0 0 0 0 2626 1804 250 250 5755;5756 6558;6559 56579 34541 Mix4_TiO2_1_3 4241 56589 34546 Mix4_TiO2_Reinj_1_3 4590 Q9UPT5;Q9UPT5-1;Q9UPT5-2;Q9UPT5-4 Q9UPT5 Q9UPT5 >sp|Q9UPT5|EXOC7_HUMAN Exocyst complex component 7 OS=Homo sapiens GN=EXOC7 PE=1 SV=3;>sp|Q9UPT5-1|EXOC7_HUMAN Isoform 1 of Exocyst complex component 7 OS=Homo sapiens GN=EXOC7;>sp|Q9UPT5-2|EXOC7_HUMAN Isoform 2 of Exocyst complex component 7 OS=Homo sapie 0.999782 36.9773 0.999782 36.9773 0.00144334 87.612 0 0 0.999733 35.7486 4.36881E-06 109.84 0.99901 30.051 0.0133391 70.357 0.992927 25.2694 0.139749 43.475 1 S SSGVPYSPAIPNK ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.36881E-06 109.84 _SSSSSGVPYpSPAIPNK_ SSSSSGVPYS(1)PAIPNK S(-54.9)S(-53.86)S(-53.86)S(-53.86)S(-57.86)GVPY(-36.98)S(36.98)PAIPNK 10 2 829.37709 0.40331 2350500 552010 0 0 1468500 0 248990 80990 2627 1805 1612 1612 2798 3188 26817 16776 Mix4_TiO2_1_1 4495 26817 16776 Mix4_TiO2_1_1 4495 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.835561 7.39466 0.835561 7.39466 0.0910442 53.765 0 0 0 0 0 0 0 0 1 S IILNSHSPAGSAA GSK3;Proline-directed 0.05 0.0910442 53.765 _IILNSHpSPAGSAAISQQDFHPK_ IILNS(0.152)HS(0.836)PAGS(0.012)AAISQQDFHPK IILNS(-7.39)HS(7.39)PAGS(-18.36)AAIS(-47.22)QQDFHPK 7 3 800.05655 0.27622 137430 137430 0 0 0 0 0 0 2628 1805 1136 1136 3238;6073 3670;6928 60000 36374 Mix4_InSol_TiO2_1 4788 30628 19030 Mix4_TiO2_Reinj_1_1 3579 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.375845 0 0.0223055 -13.8298 2.7089E-06 106.05 0 0 0.00361413 -23.0314 5.23457E-12 136.94 0 0 0.375845 0 0.0381123 58.091 7.93047E-05 -38.3713 3.02685E-06 104.63 1 S LLSESSSQSSKSP CK1 0.143 5.23457E-12 136.94 _TLLSESSpSQSSKSPSLSSK_ TLLSES(0.016)S(0.068)S(0.376)QS(0.376)S(0.02)KS(0.068)PS(0.068)LS(0.004)S(0.002)K T(-35.91)LLS(-35.91)ES(-13.59)S(-7.4)S(0)QS(0)S(-12.67)KS(-7.4)PS(-7.4)LS(-19.6)S(-23.01)K 8 3 673.98758 0.96512 0 0 0 0 0 0 0 0 2629 1805 1138 1138 3238;6073 3670;6928 60000 36374 Mix4_InSol_TiO2_1 4788 30628 19030 Mix4_TiO2_Reinj_1_1 3579 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.375845 0 0.11561 -7.3299 2.7089E-06 106.05 0 0 0.0257852 -14.4978 5.23457E-12 136.94 0 0 0.375845 0 0.0381123 58.091 0.0100391 -17.3473 3.02685E-06 104.63 1 S SESSSQSSKSPSL CK1 0.081 5.23457E-12 136.94 _TLLSESSpSQSSKSPSLSSK_ TLLSES(0.016)S(0.068)S(0.376)QS(0.376)S(0.02)KS(0.068)PS(0.068)LS(0.004)S(0.002)K T(-35.91)LLS(-35.91)ES(-13.59)S(-7.4)S(0)QS(0)S(-12.67)KS(-7.4)PS(-7.4)LS(-19.6)S(-23.01)K 10 3 673.98758 0.96512 0 0 0 0 0 0 0 0 2630 1805 1141 1141 3238;6073 3670;6928 60006 36380 Mix4_TiO2_Reinj_1_1 3948 30628 19030 Mix4_TiO2_Reinj_1_1 3579 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.72635 5.55664 0.238859 -4.17846 2.7089E-06 106.05 0 0 0.72635 5.55664 5.23457E-12 136.94 0 0 0.218805 -2.09234 0.0381123 58.091 0.155349 -5.45118 3.02685E-06 104.63 1 S SSQSSKSPSLSSK CK1;GSK3;Proline-directed 0.05 5.23457E-12 136.94 _TLLSESSSQSSKpSPSLSSK_ TLLSES(0.005)S(0.035)S(0.004)QS(0.026)S(0.003)KS(0.726)PS(0.202)LSSK T(-64.82)LLS(-47.91)ES(-21.8)S(-13.22)S(-23.03)QS(-14.5)S(-24.25)KS(5.56)PS(-5.56)LS(-52.37)S(-78.66)K 13 2 1010.4777 0.56834 1314800 0 0 0 1314800 0 0 0 2631 1805 1143 1143 3238;6073 3670;6928 60003 36377 Mix4_TiO2_1_1 3433 30628 19030 Mix4_TiO2_Reinj_1_1 3579 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.795247 8.35599 0.795247 8.35599 2.7089E-06 106.05 0 0 0.663024 7.62935 5.23457E-12 136.94 0 0 0.101437 -5.43095 0.0381123 58.091 0.545038 2.76507 3.02685E-06 104.63 1 S QSSKSPSLSSKQQ CK1 0.143 5.23457E-12 136.94 _TLLSESSSQSSKSPpSLSSK_ TLLSES(0.001)S(0.001)S(0.001)QS(0.003)S(0.009)KS(0.116)PS(0.795)LS(0.037)S(0.037)K T(-35.89)LLS(-35.89)ES(-29.1)S(-29.1)S(-28.4)QS(-24.61)S(-19.6)KS(-8.36)PS(8.36)LS(-13.34)S(-13.34)K 15 3 673.98758 0.23607 3207600 842110 0 0 2008200 0 0 357280 2632 1805 63 63 3969 4520;4521 37559 23069 Mix4_TiO2_Reinj_1_1 8295 37559 23069 Mix4_TiO2_Reinj_1_1 8295 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.975651 16.5201 0.928506 12.5585 1.28274 49.989 0.975651 16.5201 0.00127907 94.102 1 S DSGGGPSPGPGGG Proline-directed 0.05 0.00127907 94.102 _NDINEAVALLTNERPGLDYGGYEPMDSGGGPpSPGPGGGPR_ NDINEAVALLTNERPGLDY(0.002)GGY(0.001)EPMDS(0.022)GGGPS(0.976)PGPGGGPR NDINEAVALLT(-53.34)NERPGLDY(-26.69)GGY(-32.78)EPMDS(-16.52)GGGPS(16.52)PGPGGGPR 32 3 1355.2758 0.35664 185650 0.038877 64646 0 0 121010 0 0 0 2633 1805 2077 2077 4512 5125 42773 26284 Mix4_TiO2_1_1 4742 42772 26283 Mix4_TiO2_1_1 4732 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.998365 28.6592 0.998365 28.6592 3.86898E-17 140.02 0 0 0.996184 24.8029 1.83466E-11 127.68 1 S PSSPEISPQSSPR CK1;GSK3;Proline-directed 0.05 3.86898E-17 140.02 _QEAEDLSLSAPSSPEIpSPQSSPR_ QEAEDLSLSAPSSPEIS(0.998)PQS(0.001)SPR QEAEDLS(-125.38)LS(-126.19)APS(-80.93)S(-68.49)PEIS(28.66)PQS(-28.66)S(-35.59)PR 17 3 831.3778 0.17463 836440 264910 0 0 571520 0 0 0 2634 1805 2080 2080 4512 5125 42775 26286 Mix4_TiO2_Reinj_1_1 5329 42772 26283 Mix4_TiO2_1_1 4732 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.54065 1.92311 0.180702 -5.0789 3.86898E-17 140.02 0 0 0.54065 1.92311 1.83466E-11 127.68 1 S PEISPQSSPRPHR CK1 0.081 3.86898E-17 140.02 _QEAEDLSLSAPSSPEISPQpSSPR_ QEAEDLSLSAPSSPEIS(0.347)PQS(0.541)S(0.112)PR QEAEDLS(-81.66)LS(-76.8)APS(-34.84)S(-44.11)PEIS(-1.92)PQS(1.92)S(-6.84)PR 20 2 1246.5631 0.49717 325880 0 0 0 325880 0 0 0 2635 1805 1299 1299 4641 5267 43990 26958 Mix4_TiO2_Reinj_1_1 2830 43986 26952 Mix4_InSol_TiO2_1 3391 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.988963 19.5232 0.874155 8.41753 0.450719 19.045 0.988963 19.5232 0.133281 48.987 0.0216253 -16.5554 0.104282 54.076 0.427585 -1.26688 0.327753 24.097 1 S SSYRQLSVSDRSS CAMK2;CK2 0.002856 0.104282 54.076 _QLpSVSDR_ QLS(0.989)VS(0.011)DR QLS(19.52)VS(-19.52)DR 3 2 442.69731 0.258 472740 94426 0 0 378310 0 0 0 2636 1805 1301 1301 4641 5267 43986 26952 Mix4_InSol_TiO2_1 3391 43986 26952 Mix4_InSol_TiO2_1 3391 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.978375 16.5554 0.167581 -6.96118 0.450719 19.045 0.0110372 -19.5232 0.133281 48.987 0.978375 16.5554 0.104282 54.076 0.572415 1.26688 0.327753 24.097 1 S YRQLSVSDRSSIR GSK3;NEK6 0.076 0.104282 54.076 _QLSVpSDR_ QLS(0.022)VS(0.978)DR QLS(-16.56)VS(16.56)DR 5 2 442.69731 -0.052945 548430 0 0 0 0 0 327970 220470 2637 1805 1943 1943 5814 6630 57329 34922 Mix4_InSol_Tio2_Reinj_1 1542 57329 34922 Mix4_InSol_Tio2_Reinj_1 1542 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 1 96.2527 0.999704 35.2911 0.142042 35.291 1 94.5473 0.00169961 94.547 1 96.2527 0.00154641 96.253 1 S DQGGGGSPRKKVA CDK1;CDK2;Proline-directed 0.0057 0.00154641 96.253 _SVDQGGGGpSPR_ SVDQGGGGS(1)PR S(-96.25)VDQGGGGS(96.25)PR 9 2 548.72458 -0.30186 420430 17293 0 0 0 0 175610 227520 2638 1805 2561 2561 6032 6880 59610 36176 Mix4_TiO2_Reinj_1_3 9013 59598 36161 Mix4_TiO2_1_1 7592 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.994059 22.2353 0.939082 11.8796 2.34538E-99 315.24 0.9897 19.9523 8.79733E-26 182.78 0.994059 22.2353 1.86957E-58 255.73 1 S TFQRTISAQDTLA CAMK2;CK2 0.042 2.34538E-99 315.24 _TIpSAQDTLAYATALLNEK_ T(0.006)IS(0.994)AQDTLAYATALLNEK T(-22.24)IS(22.24)AQDT(-93.72)LAY(-185.92)AT(-204.71)ALLNEK 3 2 1001.9903 0.29048 6800900 1326100 82589 0 5392200 0 0 0 2639 1805 2043 2043 6588;6589 7540;7541 66785 40959 Mix4_InSol_Tio2_Reinj_3 2214 66781 40952 Mix4_InSol_TiO2_1 4050 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.915027 10.3216 0.073877 -10.9816 0.00290471 113.79 0.0131803 -18.7431 0.00246759 85.999 0.0117001 -19.267 0.00214169 106.59 0 0 0.170378 -6.87465 0.00214783 125.57 0.915027 10.3216 0.00293911 120.68 1 S LFYQRVSDQNSPV GSK3;PKA 0.042 0.00214783 125.57 _VpSDQNSPVLPK_ VS(0.915)DQNS(0.085)PVLPK VS(10.32)DQNS(-10.32)PVLPK 2 2 632.30267 -0.22227 32716 0 0 0 0 0 0 32716 2640 1805 2047 2047 6588;6589 7540;7541 66792 40972 Mix4_TiO2_Reinj_1_1 3363 66781 40952 Mix4_InSol_TiO2_1 4050 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 1 78.2051 1 65.4325 0.00290471 113.79 1 71.012 0.00246759 85.999 1 78.2051 0.00214169 106.59 0 0 1 73.3157 0.00214783 125.57 1 83.9097 0.00293911 120.68 1 S RVSDQNSPVLPKK CK1;Proline-directed 0.05 0.00214783 125.57 _VSDQNpSPVLPK_ VSDQNS(1)PVLPK VS(-78.21)DQNS(78.21)PVLPK 6 2 632.30267 -0.12225 16646000 2017300 96313 0 8690400 0 3313700 2528500 2641 1806 957 957 1287 1452 12083 7410 Mix4_InSol_TiO2_1 4603 12083 7410 Mix4_InSol_TiO2_1 4603 Q9UPU7 Q9UPU7 Q9UPU7 >sp|Q9UPU7|TBD2B_HUMAN TBC1 domain family member 2B OS=Homo sapiens GN=TBC1D2B PE=1 SV=2 1 66.1963 0.99978 36.5847 0.00109845 88.376 0 0 1 66.1963 3.78669E-09 127.05 0.999942 42.3807 0.000505662 94.055 1 S DKGELVSDEEEDT CK2 0.117 3.78669E-09 127.05 _DTSPDKGELVpSDEEEDT_ DTSPDKGELVS(1)DEEEDT DT(-111.68)S(-111.68)PDKGELVS(66.2)DEEEDT(-66.2) 11 2 973.37534 -0.11911 408220 183280 0 0 0 0 110500 114430 2642 1806 317 317 2656 3021 24788 15347 Mix4_TiO2_Reinj_1_5 3496 24788 15347 Mix4_TiO2_Reinj_1_5 3496 Q9UPU7;Q9UPU7-2 Q9UPU7 Q9UPU7 >sp|Q9UPU7|TBD2B_HUMAN TBC1 domain family member 2B OS=Homo sapiens GN=TBC1D2B PE=1 SV=2;>sp|Q9UPU7-2|TBD2B_HUMAN Isoform 2 of TBC1 domain family member 2B OS=Homo sapiens GN=TBC1D2B 0.499495 0.737809 0 0 0.499495 0.737809 0.10739 50.211 1 S YKNRHSSGDPSSE CAMK2;GSK3;PIM1/2 0.000138852 0.10739 50.211 _HSpSGDPSSEGTSGSGSVSIR_ HS(0.074)S(0.499)GDPS(0.421)S(0.004)EGT(0.001)SGSGSVSIR HS(-8.3)S(0.74)GDPS(-0.74)S(-21.14)EGT(-27.31)S(-33.29)GS(-38.44)GS(-44.67)VS(-50.04)IR 3 2 985.908 -0.058198 0 0 0 0 0 0 0 0 2643 1807 26 26 3632 4093 34141 21065 Mix4_TiO2_Reinj_1_2 3797 34140 21064 Mix4_TiO2_1_2 3087 Q9UPY5 Q9UPY5 Q9UPY5 >sp|Q9UPY5|XCT_HUMAN Cystine/glutamate transporter OS=Homo sapiens GN=SLC7A11 PE=1 SV=1 1 32.06 1 47.9866 0.0753474 47.987 1 32.06 0.28294 32.06 0 0 0 0 1 S VNGRLPSLGNKEP CAMK2 0.042 0.0753474 47.987 _LPpSLGNKEPPGQEK_ LPS(1)LGNKEPPGQEK LPS(32.06)LGNKEPPGQEK 3 3 525.25891 0.08899 117290 44672 0 0 72618 0 0 0 2644 1808 461 461 4896 5567 47011 28752 Mix4_TiO2_1_5 3356 47012 28753 Mix4_TiO2_Reinj_1_5 3881 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 Q9UPZ3 >sp|Q9UPZ3|HPS5_HUMAN Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens GN=HPS5 PE=1 SV=2;>sp|Q9UPZ3-2|HPS5_HUMAN Isoform 2 of Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens GN=HPS5 0.774289 5.53294 0.774289 5.53294 0.171675 46.628 0.497557 0 0.0704986 55.583 1 S ISSRRGSQSDEDS CAMK2;CK1;CK2;PKA;PKA/AKT 0.00111111 0.0704986 55.583 _RGpSQSDEDSCSLHSQTLSEDER_ RGS(0.774)QS(0.217)DEDS(0.008)CS(0.001)LHSQTLSEDER RGS(5.53)QS(-5.53)DEDS(-19.6)CS(-31.17)LHS(-46.63)QT(-46.63)LS(-46.63)EDER 3 3 868.34857 0.75312 74915 74915 0 0 0 0 0 0 2645 1808 463 463 4896 5567 47012 28753 Mix4_TiO2_Reinj_1_5 3881 47012 28753 Mix4_TiO2_Reinj_1_5 3881 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 Q9UPZ3 >sp|Q9UPZ3|HPS5_HUMAN Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens GN=HPS5 PE=1 SV=2;>sp|Q9UPZ3-2|HPS5_HUMAN Isoform 2 of Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens GN=HPS5 0.497557 0 0.216575 -5.53294 0.171675 46.628 0.497557 0 0.0704986 55.583 1 S SRRGSQSDEDSCS CK2;GSK3 0.081 0.0704986 55.583 _RGpSQSDEDSCSLHSQTLSEDER_ RGS(0.498)QS(0.498)DEDS(0.004)CS(0.001)LHSQTLSEDER RGS(0)QS(0)DEDS(-20.66)CS(-29.11)LHS(-55.58)QT(-55.58)LS(-55.58)EDER 5 3 868.34857 0.4307 0 0 0 0 0 0 0 0 2646 1808 534 534 5584 6364 54617 33431 Mix4_TiO2_1_5 5604 54617 33431 Mix4_TiO2_1_5 5604 Q9UPZ3;Q9UPZ3-2 Q9UPZ3 Q9UPZ3 >sp|Q9UPZ3|HPS5_HUMAN Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens GN=HPS5 PE=1 SV=2;>sp|Q9UPZ3-2|HPS5_HUMAN Isoform 2 of Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens GN=HPS5 0.986545 18.6523 0.986545 18.6523 0.0113849 70.73 0.980472 17.0353 0.0331664 55.714 1 S LPFRSPSPLVSLQ CAMK2;GSK3;Proline-directed 0.042 0.0113849 70.73 _SPpSPLVSLQAVK_ S(0.013)PS(0.987)PLVSLQAVK S(-18.65)PS(18.65)PLVS(-70.73)LQAVK 3 2 653.34434 -0.12642 160290 40462 0 0 119830 0 0 0 2647 1810 2581 2581 5063 5757 48954 29905 Mix4_InSol_TiO2_2 1985 48954 29905 Mix4_InSol_TiO2_2 1985 Q9UQ35;Q9UQ35-2 Q9UQ35 Q9UQ35 >sp|Q9UQ35|SRRM2_HUMAN Serine/arginine repetitive matrix protein 2 OS=Homo sapiens GN=SRRM2 PE=1 SV=2;>sp|Q9UQ35-2|SRRM2_HUMAN Isoform 2 of Serine/arginine repetitive matrix protein 2 OS=Homo sapiens GN=SRRM2 0.989414 19.7065 0 0 0 0 0.891181 9.13262 0.170446 32.235 0.989414 19.7065 0.01314 58.205 0.619709 2.12073 0.748296 2.1207 1 S ALKRVPSPTPAPK CAMK2;CHK1;CHK1/2;ERK/MAPK;PKA;PKD;Proline-directed 0.003024 0.01314 58.205 _RVPpSPTPAPK_ RVPS(0.989)PT(0.011)PAPK RVPS(19.71)PT(-19.71)PAPK 4 2 565.29191 -0.057838 145090 0 0 0 91280 0 27028 26779 2648 1813 199 199 571 655 5416 3239 Mix4_TiO2_Reinj_1_2 3688 5416 3239 Mix4_TiO2_Reinj_1_2 3688 Q9UQN3 Q9UQN3 Q9UQN3 >sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=Homo sapiens GN=CHMP2B PE=1 SV=1 0.999732 35.7246 0.987593 19.009 0.318645 20.776 0.999732 35.7246 0.00623753 62.62 0 0 1 S TSKATISDEEIER CK2 0.117 0.00623753 62.62 _ATIpSDEEIER_ ATIS(1)DEEIER AT(-35.72)IS(35.72)DEEIER 4 2 621.76612 0.12569 49795 12260 0 0 37535 0 0 0 2649 1814 201 201 2841;2842 3236;3237 27129 16965 Mix4_TiO2_Reinj_1_4 4195 27129 16965 Mix4_TiO2_Reinj_1_4 4195 Q9Y232;Q9Y232-2 Q9Y232 Q9Y232 >sp|Q9Y232|CDYL1_HUMAN Chromodomain Y-like protein OS=Homo sapiens GN=CDYL PE=1 SV=2;>sp|Q9Y232-2|CDYL1_HUMAN Isoform 2 of Chromodomain Y-like protein OS=Homo sapiens GN=CDYL 1 74.7419 1 21.78 0.0320522 52.737 1 41.092 0.0688268 41.092 1 74.7419 0.00257091 74.742 0.000849833 -30.703 0.110671 37.977 1 19.7854 0.395769 19.785 1 S KILVPKSPVKSRT CDK1;CDK2;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.00257091 74.742 _ILVPKpSPVK_ ILVPKS(1)PVK ILVPKS(74.74)PVK 6 2 530.81194 0.51809 660910 176900 30151 0 434530 0 0 19330 2650 1814 205 205 2842 3237 27134 16966 Mix4_InSol_TiO2_1 4284 27134 16966 Mix4_InSol_TiO2_1 4284 Q9Y232;Q9Y232-2 Q9Y232 Q9Y232 >sp|Q9Y232|CDYL1_HUMAN Chromodomain Y-like protein OS=Homo sapiens GN=CDYL PE=1 SV=2;>sp|Q9Y232-2|CDYL1_HUMAN Isoform 2 of Chromodomain Y-like protein OS=Homo sapiens GN=CDYL 0.99915 30.703 0.99915 30.703 0.110671 37.977 0 0 1 S PKSPVKSRTAVDG CK1 0.143 0.110671 37.977 _ILVPKSPVKpSR_ ILVPKS(0.001)PVKS(0.999)R ILVPKS(-30.7)PVKS(30.7)R 10 3 435.25477 -0.040716 70216 0 0 0 0 0 70216 0 2651 1815 795 795 2166;6442 2452;7370 19896 12136 Mix4_TiO2_Reinj_1_5 5709 19896 12136 Mix4_TiO2_Reinj_1_5 5709 Q9Y233-2;Q9Y233 Q9Y233-2 Q9Y233-2 >sp|Q9Y233-2|PDE10_HUMAN Isoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens GN=PDE10A;>sp|Q9Y233|PDE10_HUMAN cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens GN=PDE10A PE=1 SV=1 0.98177 17.5557 0 0 0.98177 17.5557 7.92347E-09 126.86 0.187238 -3.98644 2.63918E-07 116.94 0.612305 4.99686 0.0187049 62.032 1 S TATWISSPSVAQK CK1;Polo box;Proline-directed 0.00405 7.92347E-09 126.86 _GEETATWISpSPSVAQK_ GEETATWIS(0.001)S(0.982)PS(0.017)VAQK GEET(-86.28)AT(-53.79)WIS(-29.97)S(17.56)PS(-17.56)VAQK 10 2 885.90093 -0.34952 225470 0 0 0 137940 0 0 87533 2652 1815 797 797 2166;6442 2452;7370 65077 39929 Mix4_InSol_TiO2_1 6198 19896 12136 Mix4_TiO2_Reinj_1_5 5709 Q9Y233-2;Q9Y233 Q9Y233-2 Q9Y233-2 >sp|Q9Y233-2|PDE10_HUMAN Isoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens GN=PDE10A;>sp|Q9Y233|PDE10_HUMAN cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens GN=PDE10A PE=1 SV=1 0.468855 1.34614 0 0 0.0172363 -17.5557 7.92347E-09 126.86 0.468855 1.34614 2.63918E-07 116.94 0.193768 -4.99686 0.0187049 62.032 1 S TWISSPSVAQKAA CK1 0.081 7.92347E-09 126.86 _VIRGEETATWISSPpSVAQK_ VIRGEETATWIS(0.344)S(0.187)PS(0.469)VAQK VIRGEET(-77.68)AT(-45.61)WIS(-1.35)S(-3.99)PS(1.35)VAQK 15 2 1070.0277 -0.43066 0 0 0 0 0 0 0 0 2653 1817 34 34 5933 6766 58474 35466 Mix4_TiO2_Reinj_1_4 5123 58474 35466 Mix4_TiO2_Reinj_1_4 5123 Q9Y243;Q9Y243-2 Q9Y243 Q9Y243 >sp|Q9Y243|AKT3_HUMAN RAC-gamma serine/threonine-protein kinase OS=Homo sapiens GN=AKT3 PE=1 SV=1;>sp|Q9Y243-2|AKT3_HUMAN Isoform PKB gamma 1 of RAC-gamma serine/threonine-protein kinase OS=Homo sapiens GN=AKT3 0.999999 62.8514 0 0 0.999999 62.8514 0.00636339 65.262 1 S LLKTDGSFIGYKE PLK1 0.033462 0.00636339 65.262 _TDGpSFIGYK_ TDGS(1)FIGYK T(-62.85)DGS(62.85)FIGY(-63.52)K 4 2 534.2259 -0.21246 46929 0 0 0 46929 0 0 0 2654 1822 383 383 730 835 7045 4186 Mix4_TiO2_1_5 5274 7046 4187 Mix4_TiO2_Reinj_1_5 6068 Q9Y2D5-4;Q9Y2D5-6;Q9Y2D5-7;Q9Y2D5-5;Q9Y2D5 Q9Y2D5-4 Q9Y2D5-4 >sp|Q9Y2D5-4|AKAP2_HUMAN Isoform PALM2-AKAP2 of A-kinase anchor protein 2 OS=Homo sapiens GN=AKAP2;>sp|Q9Y2D5-6|AKAP2_HUMAN Isoform 4 of A-kinase anchor protein 2 OS=Homo sapiens GN=AKAP2;>sp|Q9Y2D5-7|AKAP2_HUMAN Isoform 5 of A-kinase anchor protein 2 OS=H 0.664457 6.17631 0.664457 6.17631 0.000343575 89.386 0.562201 5.88861 0.000215611 92.937 1 S SLQVPVSPSSTTS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000215611 92.937 _DALGDSLQVPVpSPSSTTSSR_ DALGDSLQVPVS(0.664)PS(0.16)S(0.044)T(0.054)T(0.066)S(0.01)S(0.002)R DALGDS(-84.54)LQVPVS(6.18)PS(-6.18)S(-11.78)T(-10.91)T(-10.03)S(-18.39)S(-25.94)R 12 2 1042.4808 -0.32248 224680 86475 0 0 138210 0 0 0 2655 1823 438 438 4413 5021 41992 25885 Mix4_TiO2_Reinj_1_3 6036 41992 25885 Mix4_TiO2_Reinj_1_3 6036 Q9Y2E6;Q9Y2E6-2 Q9Y2E6 Q9Y2E6 >sp|Q9Y2E6|DTX4_HUMAN Protein deltex-4 OS=Homo sapiens GN=DTX4 PE=1 SV=2;>sp|Q9Y2E6-2|DTX4_HUMAN Isoform 2 of Protein deltex-4 OS=Homo sapiens GN=DTX4 1 57.6202 1 57.6202 0.0166319 57.62 1 S DLVGKLSRCGHVY 0.0166319 57.62 _PDLVGKLpSR_ PDLVGKLS(1)R PDLVGKLS(57.62)R 8 2 532.77863 -1.0128 63600 0 0 0 63600 0 0 0 2656 1825 282 282 4604 5227 43681 26782 Mix4_TiO2_Reinj_1_4 8019 43681 26782 Mix4_TiO2_Reinj_1_4 8019 Q9Y2H1 Q9Y2H1 Q9Y2H1 >sp|Q9Y2H1|ST38L_HUMAN Serine/threonine-protein kinase 38-like OS=Homo sapiens GN=STK38L PE=1 SV=3 0.452342 0 0.399243 0 1.47848 24.887 0.452342 0 1.45212E-11 122.71 1 S RRQLAYSTVGTPD NEK6 0.076 1.45212E-11 122.71 _QLAYpSTVGTPDYIAPEVFM(ox)QTGYNK_ QLAY(0.081)S(0.452)T(0.452)VGT(0.015)PDYIAPEVFMQTGYNK QLAY(-7.49)S(0)T(0)VGT(-14.88)PDY(-43.33)IAPEVFMQT(-122.71)GY(-122.71)NK 5 3 963.77327 0.78442 0 0 0 0 0 0 0 0 2657 1826 76 76 161 188 1759 1205 Mix4_TiO2_1_5 5576 1753 1198 Mix4_InSol_TiO2_1 6725 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.950656 12.9426 0.950656 12.9426 0.000281304 90.423 0 0 0.442633 -0.929276 1.74909E-05 98.33 0.887377 9.63121 2.79726E-11 122.58 0.84746 7.53115 0.00027552 90.596 1 S LSGSWTSPQLPSR CK1;Proline-directed 0.05 2.79726E-11 122.58 _AEGGQGEQQPLSGSWTpSPQLPSR_ AEGGQGEQQPLSGSWT(0.048)S(0.951)PQLPS(0.001)R AEGGQGEQQPLS(-54.24)GS(-40.4)WT(-12.94)S(12.94)PQLPS(-29.89)R 17 3 826.37461 -0.44793 751680 0.46759 310820 0 0 0 0 259680 181180 2658 1826 475 475 911;1960 1028;2219 17953 10730 Mix4_TiO2_Reinj_1_1 5295 17953 10730 Mix4_TiO2_Reinj_1_1 5295 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.999951 43.1223 0.5 0 5.42155E-12 120.63 0.435496 -1.12666 0.449401 48.83 0.999951 43.1223 4.04696E-35 188.12 0 0 1 S DIKFDDSDTEQIA CK2 0.117 4.04696E-35 188.12 _FDDpSDTEQIAEEGDDNLANSASPSKR_ FDDS(1)DTEQIAEEGDDNLANSASPSKR FDDS(43.12)DT(-43.12)EQIAEEGDDNLANS(-188.12)AS(-188.12)PS(-188.12)KR 4 3 964.39988 0.1985 1453500 224030 0 0 1229500 0 0 0 2659 1826 1754 1754 2481;2482 2820;2821 23363 14544 Mix4_TiO2_Reinj_1_1 1841 23363 14544 Mix4_TiO2_Reinj_1_1 1841 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.999994 53.1765 0.999991 51.5591 2.82079E-05 127.78 0.998536 28.4022 0.0350156 56.416 0.999994 53.1765 2.57453E-05 128.82 0.99876 33.8299 0.206179 33.83 0.999932 44.0239 0.00061507 96.443 0.999533 35.5105 0.00371645 79.236 1 S RGTAGKSPDLSSQ CK1;GSK3;Proline-directed 0.05 2.57453E-05 128.82 _GTAGKpSPDLSSQK_ GTAGKS(1)PDLSSQK GT(-61.16)AGKS(53.18)PDLS(-53.18)S(-81.39)QK 6 2 678.31376 -0.41226 12198000 1288100 38147 0 5926200 36957 1614700 3293600 2660 1826 1758 1758 2481;2482 2820;2821 23388 14563 Mix4_TiO2_Reinj_1_5 2211 23363 14544 Mix4_TiO2_Reinj_1_1 1841 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.870472 8.49469 9.32643E-05 -40.302 2.82079E-05 127.78 0.00420312 -23.7074 0.0350156 56.416 0.870472 8.49469 2.57453E-05 128.82 0.000413495 -33.8299 0.206179 33.83 0.392961 -1.78337 0.00061507 96.443 0.0679349 -11.2982 0.00371645 79.236 1 S GKSPDLSSQKRET CK1 0.143 2.57453E-05 128.82 _GTAGKSPDLpSSQKR_ GTAGKS(0.006)PDLS(0.87)S(0.123)QKR GT(-45.17)AGKS(-21.34)PDLS(8.49)S(-8.49)QKR 10 2 756.36432 0.22442 562490 0 0 0 562490 0 0 0 2661 1826 1759 1759 2481;2482 2820;2821 23378 14551 Mix4_InSol_TiO2_1 2418 23363 14544 Mix4_TiO2_Reinj_1_1 1841 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.592498 1.78337 3.33976E-06 -54.7622 2.82079E-05 127.78 0.00420312 -23.7074 0.0350156 56.416 0.133382 -7.9769 2.57453E-05 128.82 0.000413495 -33.8299 0.206179 33.83 0.592498 1.78337 0.00061507 96.443 0.0116918 -18.9403 0.00371645 79.236 1 S KSPDLSSQKRETL 2.57453E-05 128.82 _GTAGKSPDLSpSQKR_ GTAGKS(0.014)PDLS(0.393)S(0.592)QKR GT(-40.16)AGKS(-16.12)PDLS(-1.78)S(1.78)QKR 11 2 756.36432 0.015843 1737500 0 0 0 0 0 1737500 0 2662 1826 1544 1544 2901 3304;3305 27781 17309 Mix4_TiO2_Reinj_1_1 2009 27781 17309 Mix4_TiO2_Reinj_1_1 2009 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 1 98.6834 1 63.714 0.00698268 63.714 1 98.6834 0.00231739 98.683 0 0 1 70.2445 0.00437019 70.244 1 65.6317 0.00621553 65.632 1 S ISAMDASPRNISP CDK1;Proline-directed 0.0057 0.00231739 98.683 _ISAM(ox)DApSPR_ ISAMDAS(1)PR IS(-98.68)AMDAS(98.68)PR 7 2 522.21501 0.3119 592940 73332 0 0 356800 0 80969 81842 2663 1826 1522 1522 3203 3633 30378 18899 Mix4_TiO2_Reinj_1_1 2334 30380 18905 Mix4_TiO2_Reinj_1_1 2865 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.838342 7.14824 0 0 0 0 0.838342 7.14824 0.0101551 62.038 0.553571 0.934211 0.481201 13.21 0.363465 -2.4336 0.710525 2.4336 1 S KGRKRPSVPPSPG AURORA;AURORA-1;AURORA-A;GSK3;PKA 0.006142092 0.0101551 62.038 _KRPpSVPPSPGR_ KRPS(0.838)VPPS(0.162)PGR KRPS(7.15)VPPS(-7.15)PGR 4 2 629.32681 -0.62518 139380 0 0 0 68276 0 71100 0 2664 1826 1526 1526 3203 3633 30380 18905 Mix4_TiO2_Reinj_1_1 2865 30380 18905 Mix4_TiO2_Reinj_1_1 2865 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.999999 62.038 0 0 0 0 0.999999 62.038 0.0101551 62.038 0.954426 13.2102 0.481201 13.21 0.636535 2.4336 0.710525 2.4336 1 S RPSVPPSPGRLRQ CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0101551 62.038 _KRPSVPPpSPGR_ KRPSVPPS(1)PGR KRPS(-62.04)VPPS(62.04)PGR 8 3 419.88697 0.18321 1601200 0 0 0 1526700 0 39613 34907 2665 1826 299 299 3799 4292 36098 22336 Mix4_TiO2_Reinj_1_5 3509 36092 22330 Mix4_TiO2_1_1 2558 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 1 80.4852 1 89.6865 3.26763E-11 156.65 0.833179 6.98487 0.983613 6.9849 1 80.4852 0.000485139 97.228 0 0 0.999997 55.2352 0.0323753 58.193 1 94.7572 7.78927E-05 111.5 1 S QEDAGKSPARNRS CDK1;CDK2;Proline-directed 0.0057 3.26763E-11 156.65 _LVSVQEDAGKpSPAR_ LVSVQEDAGKS(1)PAR LVS(-80.49)VQEDAGKS(80.49)PAR 11 2 768.87452 0.26349 4923100 1030500 30900 0 2695700 0 671300 494700 2666 1826 1549 1549 4084 4652 38655 23704 Mix4_TiO2_Reinj_1_5 3699 38654 23703 Mix4_InSol_Tio2_Reinj_1 3967 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 1 14.5387 0 0 0 0 1 14.5387 0.730439 14.539 0 0 1 118.883 1.76874E-06 118.88 1 S ASPRNISPGLQNG CAMK2;Proline-directed 0.042 1.76874E-06 118.88 _NIpSPGLQNGEKEDR_ NIS(1)PGLQNGEKEDR NIS(14.54)PGLQNGEKEDR 3 2 818.86997 1.9057 176910 0 0 0 72087 0 0 104830 2667 1826 305 305 5117 5821 49505 30245 Mix4_InSol_TiO2_1 6039 49507 30249 Mix4_InSol_Tio2_Reinj_1 6018 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.916634 10.4123 0.499927 0 0.00163373 95.281 0.878406 9.58072 0.368762 18.494 0.185594 -6.41407 0.00201897 90.993 0 0 0.916634 10.4123 0.00298273 80.264 0.696145 4.14161 0.00189514 104.26 1 S SPARNRSASITNL CAMK2 0.042 0.00189514 104.26 _pSASITNLSLDR_ S(0.917)AS(0.083)ITNLSLDR S(10.41)AS(-10.41)IT(-53.39)NLS(-80.26)LDR 1 2 628.79775 -0.21577 3786900 452690 29510 0 0 0 1703900 1600800 2668 1826 307 307 5117 5821 49513 30259 Mix4_TiO2_Reinj_1_1 5190 49507 30249 Mix4_InSol_Tio2_Reinj_1 6018 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.980608 19.1776 0.919022 10.6415 0.00163373 95.281 0.0967438 -9.58072 0.368762 18.494 0.980608 19.1776 0.00201897 90.993 0 0 0.499977 0 0.00298273 80.264 0.499997 0 0.00189514 104.26 1 S ARNRSASITNLSL CAMK2;PKA/AKT 0.00111111 0.00189514 104.26 _SApSITNLSLDR_ S(0.008)AS(0.981)IT(0.012)NLSLDR S(-21.14)AS(19.18)IT(-19.18)NLS(-77.44)LDR 3 2 628.79775 -0.071306 7528700 1154900 0 0 4768400 0 85273 1520200 2669 1826 318 318 5326 6063;6064 51727 31678 Mix4_TiO2_Reinj_1_1 4372 51725 31675 Mix4_TiO2_1_1 3785 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.540219 1.15861 1.71558E-12 -117.653 2.02707E-39 230.16 0 0 0.540219 1.15861 7.6444E-32 207.83 4.21889E-12 -113.736 4.21792E-12 137.22 7.15577E-07 -61.4301 6.13246E-07 115.36 1 S SLDRSGSPMVPSY CAMK2;CHK1;CHK1/2;PKD;Proline-directed 0.003192 2.02707E-39 230.16 _SGpSPM(ox)VPSYETSVSPQANR_ S(0.414)GS(0.54)PMVPS(0.034)YET(0.002)S(0.009)VSPQANR S(-1.16)GS(1.16)PMVPS(-11.98)Y(-33.07)ET(-25.25)S(-17.56)VS(-30.68)PQANR 3 2 1045.4485 -2.1071 183400 0 0 0 183400 0 0 0 2670 1826 329 329 5326 6063;6064 51726 31677 Mix4_TiO2_Reinj_1_1 4248 51725 31675 Mix4_TiO2_1_1 3785 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.999988 49.4068 0.999904 40.2564 2.02707E-39 230.16 0 0 0.999988 49.4068 7.6444E-32 207.83 0.997317 25.7168 4.21792E-12 137.22 0.994648 24.4256 6.13246E-07 115.36 1 S SYETSVSPQANRT Proline-directed 0.05 2.02707E-39 230.16 _SGSPM(ox)VPSYETSVpSPQANR_ SGSPMVPSYETSVS(1)PQANR S(-143.51)GS(-142.42)PMVPS(-92.53)Y(-118.36)ET(-76.21)S(-49.41)VS(49.41)PQANR 14 2 1045.4485 0.0847 1939400 255620 0 0 997630 0 394150 291970 2671 1826 23 23 5593 6375 54726 33519 Mix4_TiO2_2_1 3842 54729 33522 Mix4_TiO2_Reinj_1_5 6265 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.219035 0 0 0 0.219035 0 0.0778497 56.7 0.170972 -3.46304 0.000523438 81.246 0 0 0 0 1 S LPRSPTSPSHLTH CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000523438 81.246 _pSPTSPSHLTHFKPLTPDQDEPPFK_ S(0.219)PT(0.219)S(0.219)PS(0.219)HLT(0.069)HFKPLT(0.055)PDQDEPPFK S(0)PT(0)S(0)PS(0)HLT(-5.01)HFKPLT(-6.02)PDQDEPPFK 4 4 696.58237 -0.12432 0 0 0 0 0 0 0 0 2672 1826 25 25 5593 6375 54727 33520 Mix4_TiO2_Reinj_1_1 5696 54729 33522 Mix4_TiO2_Reinj_1_5 6265 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.883135 14.6181 0 0 0.761803 6.93948 0.0778497 56.7 0.883135 14.6181 0.000523438 81.246 0 0 0 0 1 S RSPTSPSHLTHFK 0.000523438 81.246 _SPTSPpSHLTHFKPLTPDQDEPPFK_ S(0.03)PT(0.03)S(0.03)PS(0.883)HLT(0.025)HFKPLTPDQDEPPFK S(-14.62)PT(-14.62)S(-14.62)PS(14.62)HLT(-15.42)HFKPLT(-49.03)PDQDEPPFK 6 3 928.44073 0.13319 781380 0 79407 0 701980 0 0 0 2673 1826 1713 1713 5746 6548;6549 56464 34481 Mix4_TiO2_1_1 4537 56466 34484 Mix4_TiO2_Reinj_1_1 5176 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.577448 1.59398 0.577448 1.59398 1.24666E-09 133.97 0 0 0.551919 1.08291 9.17308E-13 146.26 0.528559 0.801388 0.00288339 78.781 0.521187 1.19506 0.0199432 64.184 1 S DSRPKSSSPIRLP 9.17308E-13 146.26 _SpSSPIRLPEMSGGQTNR_ S(0.4)S(0.577)S(0.023)PIRLPEMSGGQTNR S(-1.59)S(1.59)S(-14.09)PIRLPEMS(-133.97)GGQT(-133.97)NR 2 3 632.9593 -0.061069 849480 334020 0 0 157990 0 164290 193190 2674 1826 1714 1714 5746 6548;6549 56463 34479 Mix4_InSol_Tio2_Reinj_1 6091 56466 34484 Mix4_TiO2_Reinj_1_1 5176 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.352794 0 0.329799 0 1.24666E-09 133.97 0 0 0.333333 0 9.17308E-13 146.26 0.0644798 -8.67355 0.00288339 78.781 0.352794 0 0.0199432 64.184 1 S SRPKSSSPIRLPE CDK1;CDK2;Polo box;Proline-directed 0.00405 9.17308E-13 146.26 _SpSSPIRLPEMSGGQTNR_ S(0.294)S(0.353)S(0.353)PIRLPEMSGGQTNR S(-0.79)S(0)S(0)PIRLPEMS(-33.03)GGQT(-33.03)NR 3 2 948.93531 0.85174 0 0 0 0 0 0 0 0 2675 1826 85 85 6186;6187 7063;7064 61250 37104 Mix4_TiO2_1_5 2462 61251 37105 Mix4_TiO2_Reinj_1_1 2575 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.811005 8.6286 0.811005 8.6286 0.0593573 45.86 0 0 0.406083 0 0.00407511 76.995 0.499235 3.65565 0.135108 36.918 0.223614 -4.90102 0.0249392 58.043 1 S LPSRTQSVRSPTP CAMK2;CK1;PKC 0.001764 0.00407511 76.995 _TQpSVRSPTPYK_ T(0.022)QS(0.811)VRS(0.111)PT(0.034)PY(0.022)K T(-15.69)QS(8.63)VRS(-8.63)PT(-13.78)PY(-15.69)K 3 2 672.32139 0.53332 21245 21245 0 0 0 0 0 0 2676 1826 88 88 6186;6187 7063;7064 61252 37106 Mix4_TiO2_Reinj_1_5 3032 61251 37105 Mix4_TiO2_Reinj_1_1 2575 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.995447 25.2302 0.862371 8.0758 0.0593573 45.86 0 0 0.995447 25.2302 0.00407511 76.995 0.668997 3.33892 0.135108 36.918 0.391728 -1.45146 0.0249392 58.043 1 S RTQSVRSPTPYKK CK1;ERK/MAPK;Proline-directed 0.0034 0.00407511 76.995 _TQSVRpSPTPYK_ TQS(0.003)VRS(0.995)PT(0.001)PYK T(-40.92)QS(-25.23)VRS(25.23)PT(-28.5)PY(-40.92)K 6 2 672.32139 0.90529 918610 68834 0 0 498560 0 351220 0 2677 1827 562 562 1228;1229 1382;1383 11513 7042 Mix4_TiO2_1_5 5597 11513 7042 Mix4_TiO2_1_5 5597 Q9Y2K2;Q9Y2K2-3 Q9Y2K2 Q9Y2K2 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3;>sp|Q9Y2K2-3|SIK3_HUMAN Isoform 3 of Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 0.996419 24.445 0.996419 24.445 0.0190485 65.566 0.79221 5.88422 0.0618639 54.828 1 S LPTERFSPVRRFS CDK1;CDK2;CK1;PKA;Proline-directed 0.0057 0.0190485 65.566 _DSNTLHLPTERFpSPVR_ DSNTLHLPT(0.004)ERFS(0.996)PVR DS(-65.57)NT(-65.57)LHLPT(-24.44)ERFS(24.44)PVR 13 3 650.31407 0.22672 489120 79297 0 0 409820 0 0 0 2678 1827 808 808 4636 5262 43928 26931 Mix4_InSol_TiO2_1 4940 43932 26935 Mix4_TiO2_Reinj_1_5 4605 Q9Y2K2;Q9Y2K2-3 Q9Y2K2 Q9Y2K2 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3;>sp|Q9Y2K2-3|SIK3_HUMAN Isoform 3 of Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 0.999751 36.6385 0.764554 8.12546 1.17442 8.1255 0 0 0.999267 34.355 0.117728 46.039 0.999751 36.6385 0.125396 44.861 0.982626 19.8301 0.710154 21.377 1 S PLSKQLSADSAEA CHK1;CK1;PKD 0.020748 0.117728 46.039 _QLpSADSAEAHSLNVNR_ QLS(1)ADSAEAHSLNVNR QLS(36.64)ADS(-36.64)AEAHS(-44.86)LNVNR 3 3 597.93889 0.20911 1200700 153740 0 0 705700 0 230950 110320 2679 1827 493 493 4808 5458 45834 28029 Mix4_TiO2_Reinj_1_6 5207 45831 28025 Mix4_TiO2_Reinj_1_3 6100 Q9Y2K2;Q9Y2K2-3 Q9Y2K2 Q9Y2K2 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3;>sp|Q9Y2K2-3|SIK3_HUMAN Isoform 3 of Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 1 69.3241 1 70.3136 6.43217E-10 123.48 1 8.03689 1.28191 8.0369 1 69.3241 5.55373E-10 125.4 0 0 1 30.5517 0.0813458 52.318 1 3.47125 1.44009 3.4713 1 S PLGRRASDGGANI CAMK2;CHK1;CHK1/2;PKA;PKD 0.003192 5.55373E-10 125.4 _RApSDGGANIQLHAQQLLK_ RAS(1)DGGANIQLHAQQLLK RAS(69.32)DGGANIQLHAQQLLK 3 3 667.34062 -0.14916 9403400 1138000 26024 0 7753100 0 98546 387660 2680 1827 568 568 4867 5533 46686 28587 Mix4_TiO2_Reinj_1_5 6107 46686 28587 Mix4_TiO2_Reinj_1_5 6107 Q9Y2K2;Q9Y2K2-3 Q9Y2K2 Q9Y2K2 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3;>sp|Q9Y2K2-3|SIK3_HUMAN Isoform 3 of Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 1 77.4564 0.999979 46.807 0.0703818 46.807 1 77.4564 0.00224947 91.161 1 S SPVRRFSDGAASI CAMK2;PKA 0.004788 0.00224947 91.161 _RFpSDGAASIQAFK_ RFS(1)DGAASIQAFK RFS(77.46)DGAAS(-77.46)IQAFK 3 3 493.23269 -0.18134 3196500 731440 0 0 2465100 0 0 0 2681 1828 132 132 617 710;711 5850 3450 Mix4_TiO2_1_5 4792 5851 3451 Mix4_TiO2_1_5 4794 Q9Y2K6 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2 0.998701 28.8573 0.998701 28.8573 6.1133E-33 189.98 0 0 0.870471 8.27386 7.45046E-17 145.77 0.5 0 1.63789 11.593 0.825185 6.73974 0.109384 52.142 1 S VADEGESESEDDD CK2 0.117 6.1133E-33 189.98 _AVPIAVADEGEpSESEDDDLKPR_ AVPIAVADEGES(0.999)ES(0.001)EDDDLKPR AVPIAVADEGES(28.86)ES(-28.86)EDDDLKPR 12 3 808.02676 -0.51798 3517500 431360 0 0 2223800 0 381530 480760 2682 1828 134 134 617 710;711 5874 3456 Mix4_TiO2_Reinj_1_5 5730 5874 3456 Mix4_TiO2_Reinj_1_5 5730 Q9Y2K6 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2 1 116.723 1 45.1168 0.188749 45.117 0 0 1 116.723 7.03713E-08 116.72 0.5 0 1.63789 11.593 0.5 0 0.109384 52.142 2 S DEGESESEDDDLK CK2 0.117 7.03713E-08 116.72 _AVPIAVADEGEpSEpSEDDDLKPR_ AVPIAVADEGES(1)ES(1)EDDDLKPR AVPIAVADEGES(116.72)ES(116.72)EDDDLKPR 14 2 1251.5197 0.49284 1359600 232150 0 0 1127400 0 0 0 2683 1828 407 407 3743;3744 4222;4223;4224 35373 21873 Mix4_TiO2_1_4 2727 35375 21875 Mix4_TiO2_Reinj_1_5 3371 Q9Y2K6;O95231 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2;>sp|O95231|VENTX_HUMAN Homeobox protein VENTX OS=Homo sapiens GN=VENTX PE=2 SV=1 0.597477 2.37794 0.597477 2.37794 0.239691 28.447 0 0 0.333881 0 0.060126 48.081 0.461917 1.01629 0.171628 33.96 0 0 2 S GHAKLSSSPPRAS 0.060126 48.081 _LSpSSPPRApSPVR_ LS(0.059)S(0.597)S(0.346)PPRAS(0.997)PVR LS(-10.18)S(2.38)S(-2.38)PPRAS(28.45)PVR 3 2 707.318 -0.16842 25918 25918 0 0 0 0 0 0 2684 1828 413 413 3744 4223;4224 35384 21877 Mix4_TiO2_Reinj_1_5 3168 35384 21877 Mix4_TiO2_Reinj_1_5 3168 Q9Y2K6 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2 0.999115 33.7795 0.756959 9.70515 0.598654 9.7051 0 0 0.999115 33.7795 0.142556 36.315 0.999444 33.96 0.171628 33.96 0 0 1 S SSPPRASPVRMAP CDK1;CDK2;PKA;Proline-directed 0.0057 0.142556 36.315 _LSSSPPRApSPVR_ LSSSPPRAS(0.999)PVR LS(-36.31)S(-36.31)S(-33.78)PPRAS(33.78)PVR 9 2 667.33483 0.22869 402560 82790 0 0 319770 0 0 0 2685 1828 371 371 5744 6545;6546 56447 34470 Mix4_TiO2_1_5 2917 56448 34471 Mix4_TiO2_Reinj_1_5 3460 Q9Y2K6 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2 0.480469 0 0.480469 0 0.0219024 62.506 0.328932 0 0.0179102 65.903 0.330943 0 0.221225 38.902 0.435655 -0.889387 0.0908113 50.617 1 S QPPSPRSSSPCRT CK1 0.081 0.0179102 65.903 _pSSSPCRTPEPDNDAHLR_ S(0.48)S(0.48)S(0.039)PCRTPEPDNDAHLR S(0)S(0)S(-10.91)PCRT(-35.93)PEPDNDAHLR 1 3 673.61772 -0.50641 0 0 0 0 0 0 0 0 2686 1828 372 372 5744 6545;6546 56446 34469 Mix4_InSol_Tio2_Reinj_1 3759 56448 34471 Mix4_TiO2_Reinj_1_5 3460 Q9Y2K6 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2 0.534664 0.889387 0.496081 -0.635683 0.15129 41.796 0.328932 0 0.0179102 65.903 0.330943 0 0.221225 38.902 0.534664 0.889387 0.0908113 50.617 1 S PPSPRSSSPCRTP CK1;PKA 0.042 0.0179102 65.903 _SpSSPCRTPEPDNDAHLR_ S(0.436)S(0.535)S(0.029)PCRT(0.001)PEPDNDAHLR S(-0.89)S(0.89)S(-12.65)PCRT(-29.05)PEPDNDAHLR 2 3 673.61772 -0.11803 252240 0 0 0 0 0 0 252240 2687 1828 373 373 5744 6545;6546 56453 34472 Mix4_TiO2_1_5 2817 56453 34472 Mix4_TiO2_1_5 2817 Q9Y2K6 Q9Y2K6 Q9Y2K6 >sp|Q9Y2K6|UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2 0.500153 0.635683 0.500153 0.635683 0.15129 41.796 0.328932 0 0.0179102 65.903 0.330943 0 0.221225 38.902 0.029016 -12.6544 0.0908113 50.617 2 S PSPRSSSPCRTPE CAMK2;CDK1;CDK2;Polo box;Proline-directed 0.00405 0.15129 41.796 _SSpSPCRpTPEPDNDAHLR_ S(0.446)S(0.496)S(0.5)PCRT(0.557)PEPDNDAHLR S(-1.26)S(-0.64)S(0.64)PCRT(1.37)PEPDNDAHLR 3 3 700.27316 0.30252 37079 37079 0 0 0 0 0 0 2688 1831 239 239 455 517 4220 2527 Mix4_InSol_TiO2_1 7396 4229 2540 Mix4_TiO2_Reinj_1_3 6922 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.999972 45.5909 0.999018 30.0764 0.000303346 88.346 0 0 0.998032 27.0511 5.9003E-07 106.45 0.999972 45.5909 0.00146858 78.472 0.998817 29.2675 0.00182432 78.055 1 S RMPRAQSYPDNHQ CAMK2;CHK1;CK2 0.0228 5.9003E-07 106.45 _AQpSYPDNHQEFSDYDNPIFEK_ AQS(1)YPDNHQEFSDYDNPIFEK AQS(45.59)Y(-45.59)PDNHQEFS(-71.3)DY(-78.17)DNPIFEK 3 2 1312.5343 -0.084197 15954000 22.839 3265300 0 0 10358000 0 1272400 1057800 2689 1831 163 163 1176 1321 11008 6754 Mix4_InSol_Tio2_Reinj_1 6456 11013 6759 Mix4_TiO2_1_3 5331 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.858709 7.83758 0.842491 7.28359 3.0857E-10 126.55 0 0 0.595677 1.70054 1.73268E-06 110.41 0 0 0.838857 7.16618 0.00041745 91.769 0.858709 7.83758 3.0342E-06 104.62 1 S PTSRDRSSPPPGY CAMK2;CK1 0.042 3.0857E-10 126.55 _DRpSSPPPGYIPDELHQVAR_ DRS(0.859)S(0.141)PPPGYIPDELHQVAR DRS(7.84)S(-7.84)PPPGY(-50.21)IPDELHQVAR 3 3 738.68283 -0.14185 29752000 5519200 0 0 21150000 0 1584000 1498500 2690 1831 164 164 1176 1321 11014 6763 Mix4_TiO2_1_3 5348 11013 6759 Mix4_TiO2_1_3 5331 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.969152 14.9719 0.969152 14.9719 3.0857E-10 126.55 0 0 0.967838 14.9355 1.73268E-06 110.41 0 0 0.499983 0 0.00041745 91.769 0.84984 7.52786 3.0342E-06 104.62 1 S TSRDRSSPPPGYI PKA;Polo box;Proline-directed 0.00405 3.0857E-10 126.55 _DRSpSPPPGYIPDELHQVAR_ DRS(0.031)S(0.969)PPPGYIPDELHQVAR DRS(-14.97)S(14.97)PPPGY(-57.43)IPDELHQVAR 4 2 1107.5206 -0.28063 27773000 5849400 0 0 21550000 0 273040 100600 2691 1831 153 153 3199;4943 3629;5619 30352 18884 Mix4_TiO2_Reinj_1_3 4436 30352 18884 Mix4_TiO2_Reinj_1_3 4436 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.999999 65.7317 0.999996 57.2136 0.0161364 57.214 0 0 0.999999 65.7317 0.00865369 65.732 0.968717 17.9191 0.380996 17.919 0.573394 4.29455 0.700274 4.2946 1 S ERKKRLSIIGPTS AURORA;AURORA-1;AURORA-A;PKA 0.006142092 0.00865369 65.732 _KRLpSIIGPTSR_ KRLS(1)IIGPTSR KRLS(65.73)IIGPT(-65.73)S(-65.73)R 4 3 436.57802 -0.16759 6616900 894160 0 0 4650700 0 619000 453080 2692 1831 331 331 4888;5023 5559;5713;5714 48511 29668 Mix4_TiO2_Reinj_1_3 5856 48511 29668 Mix4_TiO2_Reinj_1_3 5856 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 1 63.8459 0.185888 -5.71714 0.172988 42.84 1 63.8459 3.9676E-11 127.66 0.356454 1.82764 1.78587 4.1683 0.102622 -8.86995 1.44972 13.489 1 S RIRRRGSDIDNPT CAMK2;CHK1;CK2;PKA;PKD 0.004788 3.9676E-11 127.66 _RRGpSDIDNPTLTVM(ox)DISPPSR_ RRGS(1)DIDNPTLTVMDISPPSR RRGS(63.85)DIDNPT(-63.85)LT(-101.14)VMDIS(-127.66)PPS(-127.66)R 4 3 808.38434 -0.11851 1246800 0 0 0 1246800 0 0 0 2693 1831 302 302 5597 6379 54747 33529 Mix4_TiO2_1_3 6626 54748 33530 Mix4_TiO2_Reinj_1_3 7324 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.362589 1.84304 0.362589 1.84304 0.000122289 90.986 0.00389604 -20.3289 5.34622E-05 95.428 0 0 0.328268 5.42277 1.06375 37.019 1 S RSPVSFSPTDHSL CK2;Proline-directed 0.05 5.34622E-05 95.428 _SPVSFpSPTDHSLSTSSGSSIFTPEYDDSR_ S(0.004)PVS(0.002)FS(0.363)PT(0.068)DHS(0.082)LS(0.099)T(0.237)S(0.072)S(0.072)GSSIFTPEYDDSR S(-19.17)PVS(-23.2)FS(1.84)PT(-7.28)DHS(-6.46)LS(-5.63)T(-1.84)S(-7)S(-7)GS(-30.91)S(-41.62)IFT(-56.56)PEY(-74.38)DDS(-82.47)R 6 3 1057.454 0.46495 0 0 0 0 0 0 0 0 2694 1831 311 311 5597 6379 54748 33530 Mix4_TiO2_Reinj_1_3 7324 54748 33530 Mix4_TiO2_Reinj_1_3 7324 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.420255 0 0.0724099 -6.99617 0.000122289 90.986 0.420255 0 5.34622E-05 95.428 0 0 0.0536739 -7.86466 1.06375 37.019 1 S DHSLSTSSGSSIF CK1;GSK3;NEK6 0.076 5.34622E-05 95.428 _SPVSFSPTDHSLSpTSSGSSIFTPEYDDSR_ SPVS(0.001)FS(0.004)PT(0.017)DHS(0.02)LS(0.091)T(0.42)S(0.42)S(0.02)GS(0.005)S(0.001)IFTPEYDDSR S(-34.02)PVS(-27.29)FS(-20.33)PT(-13.98)DHS(-13.15)LS(-6.64)T(0)S(0)S(-13.15)GS(-19.53)S(-25.01)IFT(-60.51)PEY(-75.76)DDS(-90.12)R 15 3 1057.454 0.40372 0 0 0 0 0 0 0 0 2695 1831 35 35 5747 6550 56489 34495 Mix4_InSol_Tio2_Reinj_1 1292 56490 34496 Mix4_InSol_Tio2_Reinj_1 1347 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.561855 4.09037 0 0 0.307603 -0.972388 0.0578004 46.322 0.561855 4.09037 0.0454533 49.983 1 S ETRKAKSSSPKKQ 0.0454533 49.983 _pSSSPKKQNDVR_ S(0.562)S(0.219)S(0.219)PKKQNDVR S(4.09)S(-4.09)S(-4.09)PKKQNDVR 1 3 442.54516 0.18963 144190 0 0 0 0 0 0 144190 2696 1831 36 36 5747 6550 56490 34496 Mix4_InSol_Tio2_Reinj_1 1347 56490 34496 Mix4_InSol_Tio2_Reinj_1 1347 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.420791 1.62262 0 0 0.410089 1.43122 0.0578004 46.322 0.420791 1.62262 0.0454533 49.983 1 S TRKAKSSSPKKQN 0.0454533 49.983 _SpSSPKKQNDVR_ S(0.29)S(0.421)S(0.29)PKKQNDVR S(-1.62)S(1.62)S(-1.62)PKKQNDVR 2 2 663.3141 -0.056884 0 0 0 0 0 0 0 0 2697 1832 243 243 477 541 4466 2686 Mix4_TiO2_Reinj_1_5 4071 4466 2686 Mix4_TiO2_Reinj_1_5 4071 Q9Y2W1 Q9Y2W1 Q9Y2W1 >sp|Q9Y2W1|TR150_HUMAN Thyroid hormone receptor-associated protein 3 OS=Homo sapiens GN=THRAP3 PE=1 SV=2 0.999907 40.3148 0 0 0.999907 40.3148 0.00152951 94.133 1 S SAVSELSPRERSP CDK1;CK1;CK2;Proline-directed 0.0057 0.00152951 94.133 _ASAVSELpSPR_ ASAVSELS(1)PR AS(-94.13)AVS(-40.31)ELS(40.31)PR 8 2 548.75535 0.54702 101320 0 0 0 101320 0 0 0 2698 1832 682 682 2718 3097 25683 15865 Mix4_TiO2_1_5 5531 25683 15865 Mix4_TiO2_1_5 5531 Q9Y2W1 Q9Y2W1 Q9Y2W1 >sp|Q9Y2W1|TR150_HUMAN Thyroid hormone receptor-associated protein 3 OS=Homo sapiens GN=THRAP3 PE=1 SV=2 0.990865 23.3632 0.990865 23.3632 0.00829961 60.422 0 0 0.984202 20.9552 0.0345222 51.955 0.465965 -0.162893 0.629103 11.962 0 0 1 S HRRIDISPSTFRK Proline-directed 0.05 0.00829961 60.422 _IDIpSPSTFR_ IDIS(0.991)PS(0.005)T(0.005)FR IDIS(23.36)PS(-23.36)T(-23.36)FR 4 2 558.26027 -0.43598 161450 42257 0 0 119190 0 0 0 2699 1832 684 684 2718 3097 25680 15861 Mix4_InSol_TiO2_1 6806 25683 15865 Mix4_TiO2_1_5 5531 Q9Y2W1 Q9Y2W1 Q9Y2W1 >sp|Q9Y2W1|TR150_HUMAN Thyroid hormone receptor-associated protein 3 OS=Homo sapiens GN=THRAP3 PE=1 SV=2 0.483774 0.162893 0.102471 -8.89796 0.00829961 60.422 0 0 0.134958 -8.06047 0.0345222 51.955 0.483774 0.162893 0.629103 11.962 0 0 1 S RIDISPSTFRKHG 0.00829961 60.422 _IDISPpSTFR_ IDIS(0.466)PS(0.484)T(0.05)FR IDIS(-0.16)PS(0.16)T(-9.83)FR 6 2 558.26027 0.60323 0 0 0 0 0 0 0 0 2700 1832 672 672 4098 4667 38764 23773 Mix4_TiO2_Reinj_1_5 1590 38763 23772 Mix4_TiO2_Reinj_1_5 1579 Q9Y2W1 Q9Y2W1 Q9Y2W1 >sp|Q9Y2W1|TR150_HUMAN Thyroid hormone receptor-associated protein 3 OS=Homo sapiens GN=THRAP3 PE=1 SV=2 1 18.3236 0 0 1 18.3236 0.00775541 61.782 1 26.2721 0.275073 26.272 0 0 1 S AAKNKKSPEIHRR Proline-directed 0.05 0.00775541 61.782 _NKKpSPEIHR_ NKKS(1)PEIHR NKKS(18.32)PEIHR 4 3 396.86768 -0.14592 316420 0 0 0 294940 0 21485 0 2701 1833 502 502 2602;3058 2959;2960;3478 29155 18220 Mix4_TiO2_Reinj_1_3 4691 24321 15110 Mix4_TiO2_1_3 4416 Q9Y2X3 Q9Y2X3 Q9Y2X3 >sp|Q9Y2X3|NOP58_HUMAN Nucleolar protein 58 OS=Homo sapiens GN=NOP58 PE=1 SV=1 0.999976 48.0008 0.999898 44.4776 0.00060688 80.663 0.999976 48.0008 0.00409475 76.067 1 S IKEEPLSEEEPCT CK2 0.117 0.00060688 80.663 _KHIKEEPLpSEEEPCTSTAIASPEK_ KHIKEEPLS(1)EEEPCTSTAIASPEK KHIKEEPLS(48)EEEPCT(-54.38)S(-48)T(-53.38)AIAS(-66.38)PEK 9 3 930.7683 -0.11487 352970 115810 0 0 237150 0 0 0 2702 1833 514 514 2602;3058 2959;2960;3478 24318 15109 Mix4_TiO2_1_3 4361 24318 15109 Mix4_TiO2_1_3 4361 Q9Y2X3 Q9Y2X3 Q9Y2X3 >sp|Q9Y2X3|NOP58_HUMAN Nucleolar protein 58 OS=Homo sapiens GN=NOP58 PE=1 SV=1 0.999937 43.3329 0.999937 43.3329 0.000253704 91.25 2.30029E-07 -66.3821 0.00409475 76.067 2 S TSTAIASPEKKKK CDK1;CDK2;CK1;Proline-directed 0.0057 0.000253704 91.25 _HIKEEPLpSEEEPCTSTAIApSPEK_ HIKEEPLS(1)EEEPCTSTAIAS(1)PEK HIKEEPLS(75.49)EEEPCT(-54.57)S(-48.87)T(-43.33)AIAS(43.33)PEK 20 3 914.72542 0.14716 228610 228610 0 0 0 0 0 0 2703 1834 651 651 6365 7281 64249 39418 Mix4_TiO2_1_5 4527 64249 39418 Mix4_TiO2_1_5 4527 Q9Y2X9 Q9Y2X9 Q9Y2X9 >sp|Q9Y2X9|ZN281_HUMAN Zinc finger protein 281 OS=Homo sapiens GN=ZNF281 PE=1 SV=1 0.733827 5.52847 0.733827 5.52847 0.0266365 66.284 1 S VQEENLSPGTQTP Proline-directed 0.05 0.0266365 66.284 _VDLHTSGEHSELVQEENLpSPGTQTPSNDK_ VDLHTSGEHSELVQEENLS(0.734)PGT(0.205)QT(0.059)PS(0.001)NDK VDLHT(-57.09)S(-57.31)GEHS(-56.57)ELVQEENLS(5.53)PGT(-5.53)QT(-10.92)PS(-27.38)NDK 19 3 1076.8158 2.8397 62701 62701 0 0 0 0 0 0 2704 1835 288 288 222 256 2215 1441 Mix4_TiO2_Reinj_1_2 3862 2215 1441 Mix4_TiO2_Reinj_1_2 3862 Q9Y320;Q9Y320-2 Q9Y320 Q9Y320 >sp|Q9Y320|TMX2_HUMAN Thioredoxin-related transmembrane protein 2 OS=Homo sapiens GN=TMX2 PE=1 SV=1;>sp|Q9Y320-2|TMX2_HUMAN Isoform 2 of Thioredoxin-related transmembrane protein 2 OS=Homo sapiens GN=TMX2 0.64087 5.8186 0.332048 -0.977356 1.79175 17.188 0.64087 5.8186 5.47823E-07 100.73 1 S STPTTVSDGENKK CK2 0.117 5.47823E-07 100.73 _AGDNIPEEQPVASTPTTVpSDGENKK_ AGDNIPEEQPVAS(0.001)T(0.168)PT(0.168)T(0.023)VS(0.641)DGENKK AGDNIPEEQPVAS(-30.26)T(-5.82)PT(-5.82)T(-14.48)VS(5.82)DGENKK 19 3 888.73939 -0.12282 68414 0.16906 0 0 0 68414 0 0 0 2705 1840 266 266 4961 5642 47879 29281 Mix4_TiO2_Reinj_1_2 3631 47879 29281 Mix4_TiO2_Reinj_1_2 3631 Q9Y385 Q9Y385 Q9Y385 >sp|Q9Y385|UB2J1_HUMAN Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens GN=UBE2J1 PE=1 SV=2 0.979756 16.9217 0 0 0.979756 16.9217 6.10288E-05 105.64 0.04 -12.1751 0.0764741 50.982 0.118183 -5.71793 0.0313254 59.109 1 S QSQRRLSTSPDVI CAMK2;PKA;PKA/AKT 0.00111111 6.10288E-05 105.64 _RLpSTSPDVIQGHQPR_ RLS(0.98)T(0.02)SPDVIQGHQPR RLS(16.92)T(-16.92)S(-34.6)PDVIQGHQPR 3 2 885.93597 0.81216 376320 0 0 0 376320 0 0 0 2706 1840 268 268 4961 5642 47877 29279 Mix4_InSol_TiO2_1 4632 47879 29281 Mix4_TiO2_Reinj_1_2 3631 Q9Y385 Q9Y385 Q9Y385 >sp|Q9Y385|UB2J1_HUMAN Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens GN=UBE2J1 PE=1 SV=2 0.660034 3.42495 0 0 0.104903 -8.76945 6.10288E-05 105.64 0.660034 3.42495 0.0764741 50.982 0.440908 0 0.0313254 59.109 1 S QRRLSTSPDVIQG NEK6;Proline-directed 0.05 6.10288E-05 105.64 _RLSTpSPDVIQGHQPR_ RLS(0.04)T(0.3)S(0.66)PDVIQGHQPR RLS(-12.18)T(-3.42)S(3.42)PDVIQGHQPR 5 3 590.95974 -0.3213 95362 0 0 0 0 0 95362 0 2707 1841 188 188 1919 2170 17613 10542 Mix4_TiO2_1_4 1778 17613 10542 Mix4_TiO2_1_4 1778 Q9Y388 Q9Y388 Q9Y388 >sp|Q9Y388|RBMX2_HUMAN RNA-binding motif protein, X-linked 2 OS=Homo sapiens GN=RBMX2 PE=1 SV=2 0.691013 8.26667 0.691013 8.26667 0.0743112 45.739 0 0 0 0 1 S EQPSSSSPRRKTV CDK1;CDK2;CK1;Polo box;Proline-directed 0.00405 0.0743112 45.739 _EVQAEQPSSSpSPR_ EVQAEQPS(0.103)S(0.103)S(0.103)S(0.691)PR EVQAEQPS(-8.27)S(-8.27)S(-8.27)S(8.27)PR 11 2 741.31703 -1.1707 7398.5 7398.5 0 0 0 0 0 0 2708 1844 25 25 491 556 4542 2747 Mix4_TiO2_Reinj_1_6 5559 4542 2747 Mix4_TiO2_Reinj_1_6 5559 Q9Y3C5 Q9Y3C5 Q9Y3C5 >sp|Q9Y3C5|RNF11_HUMAN RING finger protein 11 OS=Homo sapiens GN=RNF11 PE=1 SV=1 0.999976 46.1673 0.802629 6.25703 0.06538 66.705 0.999976 46.1673 1.84133E-19 151.42 1 S SQSDRASFGEGTE AURORA;CK1;CK2;PKA 0.038874 1.84133E-19 151.42 _ApSFGEGTEPDQEPPPPYQEQVPVPVYHPTPSQTR_ AS(1)FGEGTEPDQEPPPPYQEQVPVPVYHPTPSQTR AS(46.17)FGEGT(-46.17)EPDQEPPPPY(-103.94)QEQVPVPVY(-136.98)HPT(-141.43)PS(-141.43)QT(-141.43)R 2 3 1281.2509 0.32191 383780 116190 0 0 267590 0 0 0 2709 1849 596 596 5201 5922 50415 30908 Mix4_TiO2_1_1 4993 50416 30909 Mix4_TiO2_Reinj_1_1 5559 Q9Y3R5;Q9Y3R5-2 Q9Y3R5 Q9Y3R5 >sp|Q9Y3R5|DOP2_HUMAN Protein dopey-2 OS=Homo sapiens GN=DOPEY2 PE=1 SV=4;>sp|Q9Y3R5-2|DOP2_HUMAN Isoform 2 of Protein dopey-2 OS=Homo sapiens GN=DOPEY2 0.494996 0 0.494996 0 0.000130581 95.28 0 0 0.0918266 -9.88492 5.50613E-08 117.54 0 0 1 S GIGLSASSPELSE CK2;NEK6 0.076 5.50613E-08 117.54 _SEDSGIGLSApSSPELSEHLR_ SEDSGIGLS(0.009)AS(0.495)S(0.495)PELSEHLR S(-36.78)EDS(-31.55)GIGLS(-17.19)AS(0)S(0)PELS(-36.78)EHLR 11 2 1075.9837 0.57872 0 0 0 0 0 0 0 0 2710 1849 597 597 5201 5922 50416 30909 Mix4_TiO2_Reinj_1_1 5559 50416 30909 Mix4_TiO2_Reinj_1_1 5559 Q9Y3R5;Q9Y3R5-2 Q9Y3R5 Q9Y3R5 >sp|Q9Y3R5|DOP2_HUMAN Protein dopey-2 OS=Homo sapiens GN=DOPEY2 PE=1 SV=4;>sp|Q9Y3R5-2|DOP2_HUMAN Isoform 2 of Protein dopey-2 OS=Homo sapiens GN=DOPEY2 0.894252 9.88492 0.494996 0 0.000130581 95.28 0 0 0.894252 9.88492 5.50613E-08 117.54 0 0 1 S IGLSASSPELSEH CK1;GSK3;Polo box;Proline-directed 0.00405 5.50613E-08 117.54 _SEDSGIGLSASpSPELSEHLR_ SEDSGIGLSAS(0.092)S(0.894)PELS(0.014)EHLR S(-117.54)EDS(-110.82)GIGLS(-44.51)AS(-9.88)S(9.88)PELS(-18.09)EHLR 12 3 717.65823 0.30746 480170 0 0 0 480170 0 0 0 2711 1850 56 56 5550 6325 54336 33265 Mix4_TiO2_Reinj_1_3 1645 54336 33265 Mix4_TiO2_Reinj_1_3 1645 Q9Y3T9 Q9Y3T9 Q9Y3T9 >sp|Q9Y3T9|NOC2L_HUMAN Nucleolar complex protein 2 homolog OS=Homo sapiens GN=NOC2L PE=1 SV=3 0.953283 13.1181 0 0 0.953283 13.1181 0.117773 39.341 0 0 0 0 1 S PDKPGGSPSASRR GSK3;Proline-directed 0.05 0.117773 39.341 _SPDKPGGpSPSASR_ SPDKPGGS(0.953)PS(0.046)ASR S(-39.34)PDKPGGS(13.12)PS(-13.12)AS(-39.34)R 8 2 661.79046 -0.41552 62909 0 0 0 62909 0 0 0 2712 1852 33 33 6154 7026 60954 36928 Mix4_TiO2_Reinj_1_3 6858 60954 36928 Mix4_TiO2_Reinj_1_3 6858 Q9Y3Z3;Q9Y3Z3-2 Q9Y3Z3 Q9Y3Z3 >sp|Q9Y3Z3|SAMH1_HUMAN SAM domain and HD domain-containing protein 1 OS=Homo sapiens GN=SAMHD1 PE=1 SV=2;>sp|Q9Y3Z3-2|SAMH1_HUMAN Isoform 2 of SAM domain and HD domain-containing protein 1 OS=Homo sapiens GN=SAMHD1 0.94423 12.4403 0.93125 12.1815 0.0108943 68.374 0.94423 12.4403 0.000254378 91.23 1 S SAEADWSPGLELH Proline-directed 0.05 0.000254378 91.23 _TPSNTPSAEADWpSPGLELHPDYK_ TPSNT(0.002)PS(0.054)AEADWS(0.944)PGLELHPDYK T(-41.2)PS(-40.54)NT(-27.24)PS(-12.44)AEADWS(12.44)PGLELHPDY(-70.78)K 13 3 864.71452 0.3054 2003200 500990 0 0 1502300 0 0 0 2713 1853 238 238 235 270 2332 1496 Mix4_TiO2_Reinj_1_3 6668 2331 1495 Mix4_TiO2_1_3 5842 Q9Y446 Q9Y446 Q9Y446 >sp|Q9Y446|PKP3_HUMAN Plakophilin-3 OS=Homo sapiens GN=PKP3 PE=1 SV=1 0.998416 28.0045 0.998098 27.2007 4.68817E-17 175.13 0 0 0.998416 28.0045 0.000626358 94.007 0 0 0 0 1 S PEATEVSPSRTIR CDK1;CDK2;Proline-directed 0.0057 4.68817E-17 175.13 _AGGLDWPEATEVpSPSR_ AGGLDWPEATEVS(0.998)PS(0.002)R AGGLDWPEAT(-55.28)EVS(28)PS(-28)R 13 2 876.38545 -0.054686 590520 137830 0 0 452690 0 0 0 2714 1854 174 174 688 790 6631 3932 Mix4_InSol_Tio2_Reinj_1 5785 6640 3947 Mix4_TiO2_Reinj_1_4 5240 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 0.234509 0.267187 0.0942034 -7.91245 5.81287E-12 123.9 0.00128787 -25.6108 2.30012E-12 132.05 0.0782725 -5.00719 6.88511E-05 94.055 0.234509 0.267187 0.173024 55.494 1 S VDSQKCSDVSELS CK1 0.143 2.30012E-12 132.05 _CpSDVSELSSSPPGPYHQEPYVCKPEER_ CS(0.235)DVS(0.103)ELS(0.221)S(0.221)S(0.176)PPGPY(0.022)HQEPY(0.022)VCKPEER CS(0.27)DVS(-3.56)ELS(-0.27)S(-0.27)S(-1.24)PPGPY(-10.2)HQEPY(-10.2)VCKPEER 2 2 1607.6783 -0.23135 0 0 0 0 0 0 0 0 2715 1854 177 177 688 790 6632 3934 Mix4_InSol_Tio2_Reinj_2 4340 6640 3947 Mix4_TiO2_Reinj_1_4 5240 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 0.412225 1.39461 0.0263265 -13.4492 5.81287E-12 123.9 0.00593979 -18.9719 2.30012E-12 132.05 0.0782725 -5.00719 6.88511E-05 94.055 0.412225 1.39461 0.173024 55.494 1 S QKCSDVSELSSSP CK1;GSK3 0.081 2.30012E-12 132.05 _CSDVpSELSSSPPGPYHQEPYVCKPEER_ CS(0.039)DVS(0.412)ELS(0.078)S(0.299)S(0.078)PPGPY(0.086)HQEPY(0.008)VCKPEER CS(-10.28)DVS(1.39)ELS(-7.23)S(-1.39)S(-7.23)PPGPY(-6.8)HQEPY(-17.15)VCKPEER 5 4 804.34279 -0.30872 0 0 0 0 0 0 0 0 2716 1854 181 181 688 790 6629 3927 Mix4_InSol_Tio2_Reinj_1 5779 6640 3947 Mix4_TiO2_Reinj_1_4 5240 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 0.480565 0 0.332758 0 5.81287E-12 123.9 0.468766 0 2.30012E-12 132.05 0.438016 0.800789 6.88511E-05 94.055 0.480565 0 0.173024 55.494 1 S DVSELSSSPPGPY CK1 0.143 2.30012E-12 132.05 _CSDVSELSpSSPPGPYHQEPYVCKPEER_ CSDVSELS(0.034)S(0.481)S(0.481)PPGPY(0.003)HQEPY(0.001)VCKPEER CS(-40.43)DVS(-32.97)ELS(-11.45)S(0)S(0)PPGPY(-21.94)HQEPY(-26.59)VCKPEER 9 3 1072.1213 -0.70331 0 0 0 0 0 0 0 0 2717 1854 182 182 688 790 6640 3947 Mix4_TiO2_Reinj_1_4 5240 6640 3947 Mix4_TiO2_Reinj_1_4 5240 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 0.803325 9.16779 0.729588 6.05399 5.81287E-12 123.9 0.803325 9.16779 2.30012E-12 132.05 0.760837 8.11546 6.88511E-05 94.055 0.715667 5.24184 0.173024 55.494 1 S VSELSSSPPGPYH NEK6;Polo box;Proline-directed 0.00405 2.30012E-12 132.05 _CSDVSELSSpSPPGPYHQEPYVCKPEER_ CSDVSELS(0.002)S(0.097)S(0.803)PPGPY(0.097)HQEPYVCKPEER CS(-74.86)DVS(-52.04)ELS(-25.89)S(-9.17)S(9.17)PPGPY(-9.17)HQEPY(-57.91)VCKPEER 10 3 1072.1213 0.6275 33188000 2599700 0 0 12631000 0 13684000 4272900 2718 1854 40 40 2831 3224;3225 27030 16887 Mix4_TiO2_Reinj_1_4 6786 27030 16887 Mix4_TiO2_Reinj_1_4 6786 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 1 76.6177 0 0 0 0 1 76.6177 0.000677238 90.651 1 S PKILMDSPEDADL CK2;NEK6;Proline-directed 0.05 0.000677238 90.651 _ILM(ox)DpSPEDADLFHSEEIK_ ILMDS(1)PEDADLFHSEEIK ILMDS(76.62)PEDADLFHS(-76.62)EEIK 5 3 728.98507 0.0022734 630780 0 0 0 630780 0 0 0 2719 1854 108 108 5348 6089 51941 31812 Mix4_TiO2_Reinj_1_6 6612 51927 31784 Mix4_TiO2_1_4 7011 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 1 121.477 1 105.712 4.15226E-26 184.94 0.999892 39.6582 0.228028 39.658 1 121.477 1.68844E-22 175.32 0.936683 11.7007 1.27878 11.701 0 0 0 0 1 S KLPLTRSHNNFVA NEK6 0.076 4.15226E-26 184.94 _pSHNNFVAILDLPEGEHQYK_ S(1)HNNFVAILDLPEGEHQYK S(121.48)HNNFVAILDLPEGEHQY(-121.48)K 1 3 764.3546 0.17476 23866000 3074000 41762 0 20725000 24934 0 0 2720 1857 1628 1628 2001 2265;2266 18188 10845 Mix4_TiO2_1_1 6738 18185 10844 Mix4_TiO2_Reinj_1_1 7336 Q9Y4A5;Q9Y4A5-2 Q9Y4A5 Q9Y4A5 >sp|Q9Y4A5|TRRAP_HUMAN Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP PE=1 SV=3;>sp|Q9Y4A5-2|TRRAP_HUMAN Isoform 2 of Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP 0.534636 5.8151 0.534636 5.8151 0.00266775 77.592 0 0 0.32467 1.73982 2.40631E-07 110.48 0 0 1 S TAVRPGSPSTSTM CAMK2;ERK/MAPK;GSK3;Proline-directed 0.0025 2.40631E-07 110.48 _FITLLLPGGAQTAVRPGpSPSTSTMR_ FITLLLPGGAQT(0.14)AVRPGS(0.535)PS(0.081)T(0.081)S(0.081)T(0.081)MR FIT(-77.59)LLLPGGAQT(-5.82)AVRPGS(5.82)PS(-8.18)T(-8.18)S(-8.18)T(-8.18)MR 18 3 880.11893 -1.3669 126610 126610 0 0 0 0 0 0 2721 1857 1630 1630 2001 2265;2266 18189 10846 Mix4_TiO2_Reinj_1_1 7524 18185 10844 Mix4_TiO2_Reinj_1_1 7336 Q9Y4A5;Q9Y4A5-2 Q9Y4A5 Q9Y4A5 >sp|Q9Y4A5|TRRAP_HUMAN Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP PE=1 SV=3;>sp|Q9Y4A5-2|TRRAP_HUMAN Isoform 2 of Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP 0.241022 0 0.0813072 -8.17929 0.00266775 77.592 0 0 0.241022 0 2.40631E-07 110.48 0 0 1 S VRPGSPSTSTMRL 2.40631E-07 110.48 _FITLLLPGGAQTAVRPGSPpSTSTMR_ FITLLLPGGAQT(0.001)AVRPGS(0.035)PS(0.241)T(0.241)S(0.241)T(0.241)MR FIT(-67.24)LLLPGGAQT(-25.59)AVRPGS(-8.35)PS(0)T(0)S(0)T(0)MR 20 3 880.11893 -0.77563 0 0 0 0 0 0 0 0 2722 1857 1632 1632 2001 2265;2266 18189 10846 Mix4_TiO2_Reinj_1_1 7524 18185 10844 Mix4_TiO2_Reinj_1_1 7336 Q9Y4A5;Q9Y4A5-2 Q9Y4A5 Q9Y4A5 >sp|Q9Y4A5|TRRAP_HUMAN Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP PE=1 SV=3;>sp|Q9Y4A5-2|TRRAP_HUMAN Isoform 2 of Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP 0.241022 0 0.0813072 -8.17929 0.00266775 77.592 0 0 0.241022 0 2.40631E-07 110.48 0 0 1 S PGSPSTSTMRLDL CK1 0.143 2.40631E-07 110.48 _FITLLLPGGAQTAVRPGSPpSTSTMR_ FITLLLPGGAQT(0.001)AVRPGS(0.035)PS(0.241)T(0.241)S(0.241)T(0.241)MR FIT(-67.24)LLLPGGAQT(-25.59)AVRPGS(-8.35)PS(0)T(0)S(0)T(0)MR 22 3 880.11893 -0.77563 0 0 0 0 0 0 0 0 2723 1858 1000 1000 2620 2982 24473 15187 Mix4_TiO2_Reinj_1_5 9110 24473 15187 Mix4_TiO2_Reinj_1_5 9110 Q9Y4B6;Q9Y4B6-2;Q9Y4B6-3 Q9Y4B6 Q9Y4B6 >sp|Q9Y4B6|VPRBP_HUMAN Protein VPRBP OS=Homo sapiens GN=VPRBP PE=1 SV=3;>sp|Q9Y4B6-2|VPRBP_HUMAN Isoform 2 of Protein VPRBP OS=Homo sapiens GN=VPRBP;>sp|Q9Y4B6-3|VPRBP_HUMAN Isoform 3 of Protein VPRBP OS=Homo sapiens GN=VPRBP 0.999999 60.4708 0 0 0.999999 60.4708 5.05638E-09 123.59 1 S LDRHLPSPPTLDS Proline-directed 0.05 5.05638E-09 123.59 _HLPpSPPTLDSIITEYLR_ HLPS(1)PPTLDSIITEYLR HLPS(60.47)PPT(-60.47)LDS(-79.54)IIT(-92.4)EY(-112.02)LR 4 2 1016.5112 -0.31728 227490 0 0 0 227490 0 0 0 2724 1861 229 229 5559 6334 54428 33319 Mix4_TiO2_Reinj_1_5 5245 54428 33319 Mix4_TiO2_Reinj_1_5 5245 Q9Y4E8 Q9Y4E8 Q9Y4E8 >sp|Q9Y4E8|UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens GN=USP15 PE=1 SV=3 0.999999 65.988 0 0 0.999999 65.988 0.0140102 65.988 1 S GPSTPKSPGASNF CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.0140102 65.988 _pSPGASNFSTLPK_ S(1)PGASNFSTLPK S(65.99)PGAS(-65.99)NFS(-65.99)T(-65.99)LPK 1 2 643.29484 0.25232 74618 0 0 0 74618 0 0 0 2725 1862 23 23 3431 3875 32206 19900 Mix4_TiO2_1_5 4355 32207 19901 Mix4_TiO2_Reinj_1_5 5126 Q9Y4F1-2;Q9Y4F1 Q9Y4F1-2 Q9Y4F1-2 >sp|Q9Y4F1-2|FARP1_HUMAN Isoform 2 of FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1;>sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1 PE=1 SV=1 0.891945 9.17269 0.891945 9.17269 0.019323 64.455 0 0 0.674553 3.16702 0.010377 72.927 0.496957 0 0.0639365 50.697 0.0182618 -17.3045 0.0148909 68.652 1 S PENSGISTLERGQ CK1;CK2 0.081 0.010377 72.927 _LGAPENSGIpSTLER_ LGAPENSGIS(0.892)T(0.108)LER LGAPENS(-37.95)GIS(9.17)T(-9.17)LER 10 2 762.3587 0.70512 577980 152500 0 0 425480 0 0 0 2726 1862 920 920 5547 6321 54324 33259 Mix4_TiO2_Reinj_1_5 3880 54323 33258 Mix4_TiO2_1_5 3279 Q9Y4F1-2;Q9Y4F1 Q9Y4F1-2 Q9Y4F1-2 >sp|Q9Y4F1-2|FARP1_HUMAN Isoform 2 of FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1;>sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1 PE=1 SV=1 1 70.7169 1 67.1576 2.3268E-39 219.08 1 70.7169 5.76684E-32 196.76 1 S TAADQESEDDLSA CK2 0.117 2.3268E-39 219.08 _SPDEATAADQEpSEDDLSASR_ SPDEATAADQES(1)EDDLSASR S(-146.33)PDEAT(-111.63)AADQES(70.72)EDDLS(-70.72)AS(-85.47)R 12 2 1087.4239 -0.27374 561870 5.3119 160310 0 0 401560 0 0 0 2727 1862 424 424 6582 7533 66734 40937 Mix4_TiO2_Reinj_1_5 2725 66723 40924 Mix4_InSol_TiO2_1 2930 Q9Y4F1-2;Q9Y4F1 Q9Y4F1-2 Q9Y4F1-2 >sp|Q9Y4F1-2|FARP1_HUMAN Isoform 2 of FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1;>sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1 PE=1 SV=1 0.787211 5.68322 0.208447 -5.79484 4.14122E-05 109.69 0.00715696 -21.4215 0.0811353 50.119 0.787211 5.68322 6.92535E-05 103.95 0.555596 1.28114 6.46958E-06 116.9 0.398361 -0.208148 0.00368072 78.867 1 S SAGEPGSHPSPAP 6.46958E-06 116.9 _VSAGEPGpSHPSPAPR_ VSAGEPGS(0.787)HPS(0.213)PAPR VS(-39.49)AGEPGS(5.68)HPS(-5.68)PAPR 8 3 509.23135 0.28482 394750 0 0 0 385540 0 9215 0 2728 1862 427 427 6582 7533 66733 40935 Mix4_TiO2_Reinj_1_5 2709 66723 40924 Mix4_InSol_TiO2_1 2930 Q9Y4F1-2;Q9Y4F1 Q9Y4F1-2 Q9Y4F1-2 >sp|Q9Y4F1-2|FARP1_HUMAN Isoform 2 of FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1;>sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1 PE=1 SV=1 0.999701 35.2458 0.825422 6.80288 4.14122E-05 109.69 0.992833 21.4215 0.0811353 50.119 0.999701 35.2458 6.92535E-05 103.95 0.997712 26.3958 6.46958E-06 116.9 0.99861 28.5635 0.00368072 78.867 1 S EPGSHPSPAPRRS CK1;Proline-directed 0.05 6.46958E-06 116.9 _VSAGEPGSHPpSPAPR_ VSAGEPGSHPS(1)PAPR VS(-103.95)AGEPGS(-35.25)HPS(35.25)PAPR 11 2 763.34339 0.005652 2105000 439700 69860 0 1291800 0 172000 131680 2729 1863 1676 1676 6243 7133 61976 37544 Mix4_TiO2_Reinj_1_1 7958 61976 37544 Mix4_TiO2_Reinj_1_1 7958 Q9Y4I1-3;Q9Y4I1;Q9Y4I1-2 Q9Y4I1-3 Q9Y4I1-3 >sp|Q9Y4I1-3|MYO5A_HUMAN Isoform 3 of Myosin-Va OS=Homo sapiens GN=MYO5A;>sp|Q9Y4I1|MYO5A_HUMAN Myosin-Va OS=Homo sapiens GN=MYO5A PE=1 SV=2;>sp|Q9Y4I1-2|MYO5A_HUMAN Isoform 2 of Myosin-Va OS=Homo sapiens GN=MYO5A 0.369771 0 0.352882 0 0.0170434 66.646 0 0 0.369771 0 6.59295E-09 119.4 0 0 1 S GLRKRTSSIADEG CHK1;PKA;PKD 0.020748 6.59295E-09 119.4 _TpSSIADEGTYTLDSILR_ T(0.26)S(0.37)S(0.37)IADEGTYTLDSILR T(-1.52)S(0)S(0)IADEGT(-72.27)Y(-104.51)T(-87.26)LDS(-119.4)ILR 2 2 961.44316 0.26444 0 0 0 0 0 0 0 0 2730 1863 1677 1677 6243 7133 61977 37545 Mix4_TiO2_Reinj_1_1 7968 61976 37544 Mix4_TiO2_Reinj_1_1 7958 Q9Y4I1-3;Q9Y4I1;Q9Y4I1-2 Q9Y4I1-3 Q9Y4I1-3 >sp|Q9Y4I1-3|MYO5A_HUMAN Isoform 3 of Myosin-Va OS=Homo sapiens GN=MYO5A;>sp|Q9Y4I1|MYO5A_HUMAN Myosin-Va OS=Homo sapiens GN=MYO5A PE=1 SV=2;>sp|Q9Y4I1-2|MYO5A_HUMAN Isoform 2 of Myosin-Va OS=Homo sapiens GN=MYO5A 0.833453 9.47965 0.352882 0 0.0170434 66.646 0 0 0.833453 9.47965 6.59295E-09 119.4 0 0 1 S LRKRTSSIADEGT CAMK2;CK2;PKA;PKA/AKT 0.001764 6.59295E-09 119.4 _TSpSIADEGTYTLDSILR_ T(0.072)S(0.094)S(0.833)IADEGTYTLDSILR T(-10.62)S(-9.48)S(9.48)IADEGT(-33.78)Y(-72.99)T(-78.39)LDS(-104.06)ILR 3 3 641.29787 -0.57469 33410 0 0 0 33410 0 0 0 2731 1864 433 433 5014 5702 48442 29639 Mix4_InSol_TiO2_1 5140 48443 29640 Mix4_InSol_Tio2_Reinj_1 5078 Q9Y4K4 Q9Y4K4 Q9Y4K4 >sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens GN=MAP4K5 PE=1 SV=1 0.333333 0 0 0 0.333333 0 0.000313793 88.298 0.33333 0 1.86247E-06 98.79 1 S QILRRQSSPSCGP CAMK2;CHK1;PKA;PKD 0.004788 1.86247E-06 98.79 _RQpSSPSCGPVAETSSIGNGDGISK_ RQS(0.333)S(0.333)PS(0.333)CGPVAETSSIGNGDGISK RQS(0)S(0)PS(0)CGPVAET(-60.72)S(-59.34)S(-67.16)IGNGDGIS(-88.3)K 3 3 824.36713 -0.056331 0 0 0 0 0 0 0 0 2732 1864 434 434 5014 5702 48442 29639 Mix4_InSol_TiO2_1 5140 48443 29640 Mix4_InSol_Tio2_Reinj_1 5078 Q9Y4K4 Q9Y4K4 Q9Y4K4 >sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens GN=MAP4K5 PE=1 SV=1 0.333333 0 0 0 0.333333 0 0.000313793 88.298 0.33333 0 1.86247E-06 98.79 1 S ILRRQSSPSCGPV CAMK2;CHK1;CHK1/2;PKD;Polo box;Proline-directed 0.003192 1.86247E-06 98.79 _RQpSSPSCGPVAETSSIGNGDGISK_ RQS(0.333)S(0.333)PS(0.333)CGPVAETSSIGNGDGISK RQS(0)S(0)PS(0)CGPVAET(-60.72)S(-59.34)S(-67.16)IGNGDGIS(-88.3)K 4 3 824.36713 -0.056331 0 0 0 0 0 0 0 0 2733 1864 436 436 5014 5702 48442 29639 Mix4_InSol_TiO2_1 5140 48443 29640 Mix4_InSol_Tio2_Reinj_1 5078 Q9Y4K4 Q9Y4K4 Q9Y4K4 >sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens GN=MAP4K5 PE=1 SV=1 0.333333 0 0 0 0.333333 0 0.000313793 88.298 0.33333 0 1.86247E-06 98.79 1 S RRQSSPSCGPVAE CK1 0.081 1.86247E-06 98.79 _RQpSSPSCGPVAETSSIGNGDGISK_ RQS(0.333)S(0.333)PS(0.333)CGPVAETSSIGNGDGISK RQS(0)S(0)PS(0)CGPVAET(-60.72)S(-59.34)S(-67.16)IGNGDGIS(-88.3)K 6 3 824.36713 -0.056331 0 0 0 0 0 0 0 0 2734 1864 335 335 5896;5897;5898 6725;6726;6727 58139 35311 Mix4_TiO2_Reinj_1_3 4799 58147 35317 Mix4_TiO2_Reinj_1_3 8030 Q9Y4K4 Q9Y4K4 Q9Y4K4 >sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens GN=MAP4K5 PE=1 SV=1 0.99971 35.3692 0.993816 22.0602 0.00104547 83.973 0 0 0.99971 35.3692 6.5108E-09 119.62 0.192663 -6.22255 0.448173 32.522 0.192794 -6.21892 0.929741 18.281 1 S RAERTASEINFDK CAMK2 0.042 6.5108E-09 119.62 _TApSEINFDK_ TAS(1)EINFDK T(-35.37)AS(35.37)EINFDK 3 2 552.73409 0.33693 2101100 441580 0 0 1659600 0 0 0 2735 1865 412 412 2513 2856 23653 14701 Mix4_TiO2_1_4 2838 23653 14701 Mix4_TiO2_1_4 2838 Q9Y4P8;Q9Y4P8-4 Q9Y4P8 Q9Y4P8 >sp|Q9Y4P8|WIPI2_HUMAN WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 PE=1 SV=1;>sp|Q9Y4P8-4|WIPI2_HUMAN Isoform 4 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 0.496571 0 0.496571 0 0.0395075 49.475 0 0 0.333268 0 0.132967 35.341 0.357804 0 0.50662 12.658 0 0 1 S KGTYVPSSPTRLA CK1 0.143 0.0395075 49.475 _GTYVPpSSPTR_ GTYVPS(0.497)S(0.497)PT(0.007)R GT(-49.48)Y(-49.48)VPS(0)S(0)PT(-18.6)R 6 2 572.75535 -0.20045 0 0 0 0 0 0 0 0 2736 1865 413 413 2513 2856 23653 14701 Mix4_TiO2_1_4 2838 23653 14701 Mix4_TiO2_1_4 2838 Q9Y4P8;Q9Y4P8-4 Q9Y4P8 Q9Y4P8 >sp|Q9Y4P8|WIPI2_HUMAN WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 PE=1 SV=1;>sp|Q9Y4P8-4|WIPI2_HUMAN Isoform 4 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 0.496571 0 0.496571 0 0.0395075 49.475 0 0 0.333268 0 0.132967 35.341 0.357804 0 0.50662 12.658 0 0 1 S GTYVPSSPTRLAY CDK1;CDK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0395075 49.475 _GTYVPpSSPTR_ GTYVPS(0.497)S(0.497)PT(0.007)R GT(-49.48)Y(-49.48)VPS(0)S(0)PT(-18.6)R 7 2 572.75535 -0.20045 0 0 0 0 0 0 0 0 2737 1868 250 250 3010 3424 28765 17913 Mix4_TiO2_Reinj_1_4 1195 28765 17913 Mix4_TiO2_Reinj_1_4 1195 Q9Y512 Q9Y512 Q9Y512 >sp|Q9Y512|SAM50_HUMAN Sorting and assembly machinery component 50 homolog OS=Homo sapiens GN=SAMM50 PE=1 SV=3 0.999501 33.0207 0 0 0.999501 33.0207 0.0159485 67.402 0 0 0 0 1 S FAVRKESGHSLKS CAMK2;PKA 0.004788 0.0159485 67.402 _KEpSGHSLK_ KES(1)GHSLK KES(33.02)GHS(-33.02)LK 3 2 483.22623 1.5412 43707 0 0 0 43707 0 0 0 2738 1869 388 388 5353 6094 51990 31832 Mix4_InSol_Tio2_Reinj_1 2233 51990 31832 Mix4_InSol_Tio2_Reinj_1 2233 Q9Y519 Q9Y519 Q9Y519 >sp|Q9Y519|T184B_HUMAN Transmembrane protein 184B OS=Homo sapiens GN=TMEM184B PE=1 SV=2 0.819717 7.54878 0.560046 4.05846 0.728577 4.0585 0.819717 7.54878 0.0655175 46.554 1 S GLSRSHSLSGARD CAMK2;CHK1;CHK1/2;CK1;PKA/AKT;PKD 0.00111111 0.0655175 46.554 _SHpSLSGARDNEK_ S(0.144)HS(0.82)LS(0.036)GARDNEK S(-7.55)HS(7.55)LS(-13.56)GARDNEK 3 2 690.79881 -0.51277 416790 0 0 0 0 0 174370 242420 2739 1869 403 403 6070 6924;6925 59983 36367 Mix4_TiO2_Reinj_1_1 7584 59983 36367 Mix4_TiO2_Reinj_1_1 7584 Q9Y519 Q9Y519 Q9Y519 >sp|Q9Y519|T184B_HUMAN Transmembrane protein 184B OS=Homo sapiens GN=TMEM184B PE=1 SV=2 0.999478 32.825 0.977194 18.1298 0.313605 20.993 0.999478 32.825 0.00665287 61.339 1 S KTLLLSSDDEF__ CK2;NEK6 0.076 0.00665287 61.339 _TLLLSpSDDEF_ TLLLS(0.001)S(0.999)DDEF T(-61.34)LLLS(-32.83)S(32.83)DDEF 6 2 610.26013 -0.29302 164970 29123 0 0 135850 0 0 0 2740 1872 136 136 5275 6003 51200 31378 Mix4_TiO2_Reinj_1_2 4430 51200 31378 Mix4_TiO2_Reinj_1_2 4430 Q9Y580 Q9Y580 Q9Y580 >sp|Q9Y580|RBM7_HUMAN RNA-binding protein 7 OS=Homo sapiens GN=RBM7 PE=1 SV=1 0.977208 16.7433 0 0 0.977208 16.7433 0.00594104 63.534 0 0 0 0 1 S IIQRSFSSPENFQ 14-3-3 binding;CAMK2;CHK1;CK2;PKD 0.0001701 0.00594104 63.534 _SFpSSPENFQR_ S(0.002)FS(0.977)S(0.021)PENFQR S(-26.66)FS(16.74)S(-16.74)PENFQR 3 2 639.76117 0.037791 32248 0 0 0 32248 0 0 0 2741 1872 137 137 5275 6003 51199 31377 Mix4_TiO2_Reinj_1_2 4304 51200 31378 Mix4_TiO2_Reinj_1_2 4430 Q9Y580 Q9Y580 Q9Y580 >sp|Q9Y580|RBM7_HUMAN RNA-binding protein 7 OS=Homo sapiens GN=RBM7 PE=1 SV=1 0.987669 19.0418 0 0 0.987669 19.0418 0.00594104 63.534 0 0 0 0 1 S IQRSFSSPENFQR CK1;Polo box;Proline-directed 0.00405 0.00594104 63.534 _SFSpSPENFQR_ SFS(0.012)S(0.988)PENFQR S(-47.96)FS(-19.04)S(19.04)PENFQR 4 2 639.76117 0.28224 40991 0 0 0 40991 0 0 0 2742 1874 121 121 6555 7498 66296 40711 Mix4_TiO2_Reinj_1_4 3102 66294 40709 Mix4_TiO2_Reinj_1_3 3100 Q9Y5J1 Q9Y5J1 Q9Y5J1 >sp|Q9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens GN=UTP18 PE=1 SV=3 1 132.383 1 119.814 5.97534E-09 121.08 1 132.383 1.01495E-12 145.18 1 85.8707 0.00136258 85.871 1 129.685 2.82826E-09 129.68 2 S VQEHEDSGDSEVE 1.01495E-12 145.18 _VQEHEDpSGDpSEVENEAK_ VQEHEDS(1)GDS(1)EVENEAK VQEHEDS(132.38)GDS(132.38)EVENEAK 7 2 1031.3697 0.010255 2018500 337520 0 0 1499200 0 68963 112820 2743 1874 124 124 6555 7498 66296 40711 Mix4_TiO2_Reinj_1_4 3102 66294 40709 Mix4_TiO2_Reinj_1_3 3100 Q9Y5J1 Q9Y5J1 Q9Y5J1 >sp|Q9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens GN=UTP18 PE=1 SV=3 1 132.383 1 119.814 5.97534E-09 121.08 1 132.383 1.01495E-12 145.18 1 85.8707 0.00136258 85.871 1 129.685 2.82826E-09 129.68 2 S HEDSGDSEVENEA CK1;CK2 0.081 1.01495E-12 145.18 _VQEHEDpSGDpSEVENEAK_ VQEHEDS(1)GDS(1)EVENEAK VQEHEDS(132.38)GDS(132.38)EVENEAK 10 2 1031.3697 0.010255 2018500 337520 0 0 1499200 0 68963 112820 2744 1877 1686 1686 2662 3028;3029 24845 15370 Mix4_InSol_Tio2_Reinj_1 2737 24842 15367 Mix4_InSol_TiO2_1 2685 Q9Y5S2 Q9Y5S2 Q9Y5S2 >sp|Q9Y5S2|MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta OS=Homo sapiens GN=CDC42BPB PE=1 SV=2 0.533192 0.658299 2.91198E-05 -45.3433 0.0358437 58.377 0.0316349 -14.8537 3.2699E-17 153.84 0.0634888 -11.4956 7.95872E-24 165.75 0.533192 0.658299 0.000456576 83.036 1 S SNSSNPSGPPSPN CK1;GSK3 0.081 7.95872E-24 165.75 _HSTPSNSSNPpSGPPSPNSPHR_ HSTPSNSS(0.004)NPS(0.533)GPPS(0.458)PNS(0.003)PHR HS(-30.3)T(-30.3)PS(-30.3)NS(-30.3)S(-21.73)NPS(0.66)GPPS(-0.66)PNS(-22.45)PHR 11 2 1110.9745 0.54598 21071 0 0 0 0 0 0 21071 2745 1877 1690 1690 2662 3028;3029 24848 15376 Mix4_TiO2_Reinj_1_4 2392 24842 15367 Mix4_InSol_TiO2_1 2685 Q9Y5S2 Q9Y5S2 Q9Y5S2 >sp|Q9Y5S2|MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta OS=Homo sapiens GN=CDC42BPB PE=1 SV=2 0.998881 29.5459 0.996583 24.6955 0.0358437 58.377 0.998881 29.5459 3.2699E-17 153.84 0.996011 23.9744 7.95872E-24 165.75 0.808698 6.26116 0.000456576 83.036 1 S NPSGPPSPNSPHR CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 7.95872E-24 165.75 _HSTPSNSSNPSGPPpSPNSPHR_ HSTPSNSSNPSGPPS(0.999)PNS(0.001)PHR HS(-94.49)T(-91.44)PS(-85.81)NS(-85.81)S(-85.81)NPS(-50.1)GPPS(29.55)PNS(-29.55)PHR 15 3 740.98546 0.45374 2488500 18845 0 0 2028800 0 276830 163980 2746 1877 1693 1693 2662 3028;3029 24856 15380 Mix4_TiO2_Reinj_1_5 2480 24856 15380 Mix4_TiO2_Reinj_1_5 2480 Q9Y5S2 Q9Y5S2 Q9Y5S2 >sp|Q9Y5S2|MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta OS=Homo sapiens GN=CDC42BPB PE=1 SV=2 0.999553 37.328 0.00338036 -24.6955 0.0358437 58.377 0.999553 37.328 0.131576 48.826 0.00933322 -19.8222 7.95872E-24 165.75 0.191281 -6.26116 0.000456576 83.036 2 S GPPSPNSPHRSQL CDK1;CDK2;CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 0.131576 48.826 _HSTPSNSSNPSGPPpSPNpSPHR_ HSTPSNSSNPS(0.001)GPPS(0.999)PNS(1)PHR HS(-48.83)T(-48.83)PS(-48.83)NS(-48.83)S(-48.83)NPS(-35.87)GPPS(35.87)PNS(37.33)PHR 18 3 767.6409 0.4374 224200 0 0 0 224200 0 0 0 2747 1879 321 321 4107 4676 38880 23846 Mix4_InSol_Tio2_Reinj_1 3783 38880 23846 Mix4_InSol_Tio2_Reinj_1 3783 Q9Y5U2;Q9Y5U2-2 Q9Y5U2 Q9Y5U2 >sp|Q9Y5U2|TSSC4_HUMAN Protein TSSC4 OS=Homo sapiens GN=TSSC4 PE=1 SV=3;>sp|Q9Y5U2-2|TSSC4_HUMAN Isoform 2 of Protein TSSC4 OS=Homo sapiens GN=TSSC4 0.969988 15.1036 0 0 0.854715 7.70238 0.00391549 83.337 0.969988 15.1036 0.00179671 93.257 1 S FRNKSSSPEDPGA CK2;Polo box;Proline-directed 0.00405 0.00179671 93.257 _NKSSpSPEDPGAEV_ NKSS(0.03)S(0.97)PEDPGAEV NKS(-41.99)S(-15.1)S(15.1)PEDPGAEV 5 2 698.78504 0.3616 128460 0 0 0 0 0 62450 66008 2748 1882 158 158 1876 2119 17269 10383 Mix4_TiO2_Reinj_1_2 2802 17269 10383 Mix4_TiO2_Reinj_1_2 2802 Q9Y5Y5-2;Q9Y5Y5 Q9Y5Y5-2 Q9Y5Y5-2 >sp|Q9Y5Y5-2|PEX16_HUMAN Isoform 2 of Peroxisomal membrane protein PEX16 OS=Homo sapiens GN=PEX16;>sp|Q9Y5Y5|PEX16_HUMAN Peroxisomal membrane protein PEX16 OS=Homo sapiens GN=PEX16 PE=1 SV=1 0.999999 61.4992 0 0 0.999999 61.4992 7.70871E-07 102.96 1 S PPDGDHSPGNHEQ Proline-directed 0.05 7.70871E-07 102.96 _ETQAQPPDGDHpSPGNHEQSYVGK_ ETQAQPPDGDHS(1)PGNHEQSYVGK ET(-92.72)QAQPPDGDHS(61.5)PGNHEQS(-61.5)Y(-62.5)VGK 12 3 853.35751 -0.69762 202860 0.096394 0 0 0 202860 0 0 0 2749 1885 110 110 273 313 2609 1636 Mix4_TiO2_1_3 6312 2609 1636 Mix4_TiO2_1_3 6312 Q9Y616 Q9Y616 Q9Y616 >sp|Q9Y616|IRAK3_HUMAN Interleukin-1 receptor-associated kinase 3 OS=Homo sapiens GN=IRAK3 PE=1 SV=1 0.499144 0 0.499144 0 0.000909121 90.19 0 0 1 S NYGAVLSPSEKSY CK2;ERK/MAPK;Proline-directed 0.0034 0.000909121 90.19 _AIHLITNYGAVLpSPSEK_ AIHLITNY(0.002)GAVLS(0.499)PS(0.499)EK AIHLIT(-50.82)NY(-24.66)GAVLS(0)PS(0)EK 13 2 946.97952 0.36436 0 0 0 0 0 0 0 0 2750 1885 112 112 273 313 2609 1636 Mix4_TiO2_1_3 6312 2609 1636 Mix4_TiO2_1_3 6312 Q9Y616 Q9Y616 Q9Y616 >sp|Q9Y616|IRAK3_HUMAN Interleukin-1 receptor-associated kinase 3 OS=Homo sapiens GN=IRAK3 PE=1 SV=1 0.499144 0 0.499144 0 0.000909121 90.19 0 0 1 S GAVLSPSEKSYQE NEK6 0.076 0.000909121 90.19 _AIHLITNYGAVLpSPSEK_ AIHLITNY(0.002)GAVLS(0.499)PS(0.499)EK AIHLIT(-50.82)NY(-24.66)GAVLS(0)PS(0)EK 15 2 946.97952 0.36436 0 0 0 0 0 0 0 0 2751 1886 956 956 376 432 3570 2123 Mix4_TiO2_1_1 3171 3570 2123 Mix4_TiO2_1_1 3171 Q9Y618;Q9Y618-3;Q9Y618-4;Q9Y618-5 Q9Y618 Q9Y618 >sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepressor 2 OS=Homo sapiens GN=NCOR2 PE=1 SV=2;>sp|Q9Y618-3|NCOR2_HUMAN Isoform h-SMRT of Nuclear receptor corepressor 2 OS=Homo sapiens GN=NCOR2;>sp|Q9Y618-4|NCOR2_HUMAN Isoform SMRTe of Nuclear receptor corepress 1 38.4458 1 38.4458 0.116242 38.446 0 0 1 S DPRANASPQKPLD CDK1;CDK2;Proline-directed 0.0057 0.116242 38.446 _ANApSPQKPLDLK_ ANAS(1)PQKPLDLK ANAS(38.45)PQKPLDLK 4 2 681.34487 -0.15817 20467 20467 0 0 0 0 0 0 2752 1888 354 354 3698 4170 34838 21614 Mix4_TiO2_Reinj_1_4 7311 34837 21613 Mix4_TiO2_1_4 6733 Q9Y679;Q9Y679-2;Q9Y679-3 Q9Y679 Q9Y679 >sp|Q9Y679|AUP1_HUMAN Ancient ubiquitous protein 1 OS=Homo sapiens GN=AUP1 PE=1 SV=1;>sp|Q9Y679-2|AUP1_HUMAN Isoform Short of Ancient ubiquitous protein 1 OS=Homo sapiens GN=AUP1;>sp|Q9Y679-3|AUP1_HUMAN Isoform 3 of Ancient ubiquitous protein 1 OS=Homo sap 0.999995 56.837 0.999986 48.652 2.93508E-12 128.34 0.999995 56.837 3.44125E-08 114.99 0.941237 12.86 0.00374925 77.542 0.742926 10.5691 1.90405 19.472 1 S QSSFPPSPGPSPD CK1;ERK/MAPK;GSK3;Proline-directed;WW GroupIV 0.0023175 2.93508E-12 128.34 _LRPQSAQSSFPPpSPGPSPDVQLATLAQR_ LRPQSAQSSFPPS(1)PGPSPDVQLATLAQR LRPQS(-66.88)AQS(-57.93)S(-57.93)FPPS(56.84)PGPS(-56.84)PDVQLAT(-86.7)LAQR 13 3 1004.8361 -0.0538 2341400 592870 0 0 1564700 0 100940 82888 2753 1890 214 214 1652 1854;1855 15164 9146 Mix4_TiO2_Reinj_1_5 4913 15162 9144 Mix4_TiO2_Reinj_1_1 4338 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.988051 19.1743 0.206106 -5.89786 0.00060596 80.691 0.0857057 -13.2911 1.70072 13.291 0.988051 19.1743 1.41373E-12 136.64 0.00246274 -26.0644 1.17656 26.064 0.555375 -2.04437 0.000529249 82.99 0.454066 -0.800222 3.80808E-05 97.713 2 S LEKPIQSKPQSPV GSK3 0.081 1.41373E-12 136.64 _ELEKPIQpSKPQSPVIQAAAVpSPK_ ELEKPIQS(0.988)KPQS(0.012)PVIQAAAVS(1)PK ELEKPIQS(19.17)KPQS(-19.17)PVIQAAAVS(91.86)PK 8 2 1303.1555 0.37132 513860 0 0 0 480330 0 33528 0 2754 1890 218 218 1652;4433 1854;1855;5043 15162 9144 Mix4_TiO2_Reinj_1_1 4338 15162 9144 Mix4_TiO2_Reinj_1_1 4338 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.999993 51.3157 0.999958 43.7706 0.00060596 80.691 0.957147 13.2911 1.70072 13.291 0.999993 51.3157 1.41373E-12 136.64 0.00246274 -26.0644 1.17656 26.064 0.996559 24.6186 0.000529249 82.99 0.999906 40.2473 3.80808E-05 97.713 2 S IQSKPQSPVIQAA CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.41373E-12 136.64 _ELEKPIQSKPQpSPVIQAAAVpSPK_ ELEKPIQSKPQS(1)PVIQAAAVS(1)PK ELEKPIQS(-51.32)KPQS(51.32)PVIQAAAVS(132.04)PK 12 3 869.10612 1.4074 16257000 2265700 29726 0 9879500 0 2173500 1908500 2755 1890 227 227 1652;4433 1854;1855;5043 42155 25974 Mix4_TiO2_Reinj_1_5 4827 15209 9188 Mix4_TiO2_Reinj_1_5 5041 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 1 134.199 1 161.314 2.47793E-11 161.31 0.999913 40.598 4.28118E-05 97.572 1 134.199 4.45574E-33 179.84 0.995075 26.0644 1.17656 26.064 1 68.5217 3.45073E-17 141.82 1 64.4912 0.000110672 95.538 1 S IQAAAVSPKFVRL CDK1;Proline-directed 0.0057 4.45574E-33 179.84 _PQSPVIQAAAVpSPK_ PQSPVIQAAAVS(1)PK PQS(-134.2)PVIQAAAVS(134.2)PK 12 2 736.87907 0.24464 32773000 5254400 558120 0 19538000 24004 3437000 3961800 2756 1890 276 276 1789;2464 2019;2796 23162 14457 Mix4_TiO2_Reinj_1_5 4202 23162 14457 Mix4_TiO2_Reinj_1_5 4202 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.5 0 0.475667 -0.340112 2.18325E-16 172.21 0.5 0 4.67763E-17 175.14 1 S APRERGSSLSGTD PKA 0.042 4.67763E-17 175.14 _GpSSLSGTDDGAQEVVK_ GS(0.5)S(0.5)LSGTDDGAQEVVK GS(0)S(0)LS(-69.22)GT(-109.78)DDGAQEVVK 2 2 815.35381 -0.075291 868490 52.516 0 0 0 868490 0 0 0 2757 1890 277 277 1789;2464 2019;2796 23161 14456 Mix4_TiO2_1_5 3466 23162 14457 Mix4_TiO2_Reinj_1_5 4202 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.891418 9.14438 0.891418 9.14438 2.18325E-16 172.21 0.5 0 4.67763E-17 175.14 1 S PRERGSSLSGTDD CAMK2;PKA/AKT 0.001764 4.67763E-17 175.14 _GSpSLSGTDDGAQEVVK_ GS(0.109)S(0.891)LSGTDDGAQEVVK GS(-9.14)S(9.14)LS(-44.93)GT(-89.51)DDGAQEVVK 3 2 815.35381 -0.25732 1355000 81.932 486480 0 0 868490 0 0 0 2758 1890 1525 1525 2390 2707;2709 22297 13884 Mix4_TiO2_Reinj_1_5 5112 22297 13884 Mix4_TiO2_Reinj_1_5 5112 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 1 90.5168 0.0138587 -18.3983 8.80007E-16 184.58 0.140095 -6.16794 1.01109 6.1679 1 90.5168 0.000159031 104.47 0 0 3.42149E-05 -44.657 6.03887E-07 131.14 2.08868E-05 -46.8011 9.11812E-05 110.35 2 S PSERGQSQLSNPT CAMK2 0.042 0.000159031 104.47 _GQpSQLpSNPTDDSWK_ GQS(1)QLS(0.999)NPT(0.001)DDSWK GQS(90.52)QLS(29.88)NPT(-29.88)DDS(-88.73)WK 3 2 861.82404 0.30368 700980 2.6096 0 0 0 700980 0 0 0 2759 1890 1528 1528 2390 2707;2709 22260 13872 Mix4_InSol_Tio2_Reinj_1 5249 22261 13873 Mix4_TiO2_1_1 3876 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.999958 46.8011 0.999865 38.7215 8.80007E-16 184.58 0.579716 6.16794 1.01109 6.1679 0.998379 27.8984 5.94858E-07 131.23 0 0 0.999802 37.8653 6.03887E-07 131.14 0.999958 46.8011 9.11812E-05 110.35 1 S RGQSQLSNPTDDS CK1 0.081 8.80007E-16 184.58 _GQSQLpSNPTDDSWK_ GQSQLS(1)NPTDDSWK GQS(-46.8)QLS(46.8)NPT(-46.8)DDS(-93.11)WK 6 2 821.84087 0.51659 4187300 15.588 851140 9402.2 0 2644400 0 405400 276960 2760 1890 1511 1511 2612 2972;2973 24434 15163 Mix4_TiO2_Reinj_1_5 5783 24433 15162 Mix4_TiO2_Reinj_1_5 5760 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.845533 6.65953 0 0 0.845533 6.65953 0.0156422 61.83 2 S VDLDRQSLSSIDK AURORA;AURORA-1;PKA 0.020748 0.0156422 61.83 _HLDVDLDRQpSLSpSIDKNPSER_ HLDVDLDRQS(0.846)LS(0.302)S(0.846)IDKNPS(0.007)ER HLDVDLDRQS(6.66)LS(-6.66)S(6.66)IDKNPS(-24.59)ER 10 4 646.79146 0.10198 2207000 0 0 0 2207000 0 0 0 2761 1890 1513 1513 2612 2972;2973 24433 15162 Mix4_TiO2_Reinj_1_5 5760 24433 15162 Mix4_TiO2_Reinj_1_5 5760 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.671827 0.754114 0 0 0.671827 0.754114 0.0156422 61.83 2 S LDRQSLSSIDKNP CK2 0.117 0.0156422 61.83 _HLDVDLDRQSLpSpSIDKNPSER_ HLDVDLDRQS(0.611)LS(0.672)S(0.631)IDKNPS(0.087)ER HLDVDLDRQS(-0.75)LS(0.75)S(0.75)IDKNPS(-8.79)ER 12 3 862.05286 -0.42878 1789600 0 0 0 1789600 0 0 0 2762 1890 1514 1514 2612 2972;2973 24434 15163 Mix4_TiO2_Reinj_1_5 5783 24433 15162 Mix4_TiO2_Reinj_1_5 5760 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.845533 6.65953 0 0 0.845533 6.65953 0.0156422 61.83 2 S DRQSLSSIDKNPS CK1 0.081 0.0156422 61.83 _HLDVDLDRQpSLSpSIDKNPSER_ HLDVDLDRQS(0.846)LS(0.302)S(0.846)IDKNPS(0.007)ER HLDVDLDRQS(6.66)LS(-6.66)S(6.66)IDKNPS(-24.59)ER 13 4 646.79146 0.10198 2207000 0 0 0 2207000 0 0 0 2763 1890 1782 1782 2945 3352 28099 17456 Mix4_TiO2_Reinj_1_5 8986 28098 17455 Mix4_TiO2_Reinj_1_1 8651 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 1 76.68 1 95.3037 1.37543E-06 114.23 1 68.148 0.000841177 88.652 1 76.68 2.66154E-15 141.56 1 S QVPAALSPVW___ Proline-directed 0.05 2.66154E-15 141.56 _IWIPEEPSQVPAALpSPVW_ IWIPEEPSQVPAALS(1)PVW IWIPEEPS(-76.68)QVPAALS(76.68)PVW 15 2 1050.0161 0.14787 761960 227310 51714 0 482940 0 0 0 2764 1890 346 346 4735 5377 45133 27620 Mix4_TiO2_1_5 4274 45135 27622 Mix4_TiO2_Reinj_1_5 4915 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.826801 8.93282 0.826801 8.93282 0.00364847 75.889 0 0 0.384487 0 0.000396687 85.112 0 0 1 S IADDRQSLSSADN AURORA;AURORA-1;PKA 0.020748 0.000396687 85.112 _QpSLSSADNLESDAQGHQVAAR_ QS(0.827)LS(0.106)S(0.067)ADNLESDAQGHQVAAR QS(8.93)LS(-8.93)S(-10.88)ADNLES(-75.89)DAQGHQVAAR 2 2 1132.5006 0.3723 100290 0.16041 100290 0 0 0 0 0 0 2765 1890 348 348 4735 5377 45131 27618 Mix4_TiO2_1_1 3891 45135 27622 Mix4_TiO2_Reinj_1_5 4915 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.615895 2.05379 0.615895 2.05379 0.00364847 75.889 0 0 0.60113 1.78832 0.000396687 85.112 0 0 1 S DDRQSLSSADNLE CK2 0.117 0.000396687 85.112 _QSLpSSADNLESDAQGHQVAAR_ QSLS(0.616)S(0.384)ADNLESDAQGHQVAAR QS(-33.96)LS(2.05)S(-2.05)ADNLES(-42.18)DAQGHQVAAR 4 3 755.33615 0.31549 940140 1.5037 172160 0 0 767980 0 0 0 2766 1890 349 349 4735 5377 45132 27619 Mix4_TiO2_1_5 4273 45135 27622 Mix4_TiO2_Reinj_1_5 4915 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.771289 5.28837 0.771289 5.28837 0.00364847 75.889 0 0 0.398232 -1.78832 0.000396687 85.112 0 0 1 S DRQSLSSADNLES CK1 0.081 0.000396687 85.112 _QSLSpSADNLESDAQGHQVAAR_ QSLS(0.228)S(0.771)ADNLESDAQGHQVAAR QS(-37.91)LS(-5.29)S(5.29)ADNLES(-33.41)DAQGHQVAAR 5 3 755.33615 0.15202 399000 0.63816 399000 0 0 0 0 0 0 2767 1890 614 614 4825 5475;5476;5477;5478 46062 28165 Mix4_TiO2_Reinj_1_5 6870 46073 28167 Mix4_TiO2_1_5 5525 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.948049 12.6721 0.806154 6.79509 9.7911E-19 141.3 0 0 0.948049 12.6721 1.47622E-12 125.08 0 0 0.439824 2.43762 0.0420388 60.97 1 S DMARRCSVTSMES AURORA;AURORA-1;AURORA-A;CAMK2;CHK1;PKA;PKA/AKT 0.00111111 9.7911E-19 141.3 _RCpSVTSMESTVSSGTQTTVQDDPEQFEVIK_ RCS(0.948)VT(0.051)S(0.001)MESTVSSGTQTTVQDDPEQFEVIK RCS(12.67)VT(-12.67)S(-31.83)MES(-43.42)T(-43.42)VS(-65.19)S(-65.19)GT(-65.19)QT(-81.3)T(-86.52)VQDDPEQFEVIK 3 3 1142.8407 0.20826 1699400 413680 0 0 1285700 0 0 0 2768 1890 617 617 4825 5475;5476;5477;5478 46081 28171 Mix4_TiO2_Reinj_1_1 5950 46084 28172 Mix4_TiO2_1_1 5876 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.338501 0 0.157742 -4.6657 7.78425E-06 98.351 0 0 0.338501 0 0.000131814 90.693 0 0 0.250909 -2.43762 0.0420388 60.97 2 S RRCSVTSMESTVS CK1 0.081 7.78425E-06 98.351 _RCpSVTpSM(ox)ESTVSSGTQTTVQDDPEQFEVIK_ RCS(0.777)VT(0.196)S(0.339)MES(0.339)T(0.339)VS(0.005)S(0.005)GT(0.001)QTTVQDDPEQFEVIK RCS(6.23)VT(-6.23)S(0)MES(0)T(0)VS(-21.22)S(-21.22)GT(-28.37)QT(-55.77)T(-61.82)VQDDPEQFEVIK 6 3 1174.8278 -0.59549 0 0 0 0 0 0 0 0 2769 1890 620 620 4825 5475;5476;5477;5478 46080 28170 Mix4_TiO2_1_1 5355 46084 28172 Mix4_TiO2_1_1 5876 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.465736 0 0.465736 0 7.78425E-06 98.351 0 0 0.338501 0 0.000131814 90.693 0 0 0.0220971 -12.9894 0.0420388 60.97 2 S SVTSMESTVSSGT CK1;GSK3 0.081 7.78425E-06 98.351 _RCpSVTSM(ox)EpSTVSSGTQTTVQDDPEQFEVIK_ RCS(0.429)VT(0.427)S(0.158)MES(0.466)T(0.466)VS(0.016)S(0.016)GT(0.016)QT(0.006)T(0.002)VQDDPEQFEVIK RCS(0)VT(0)S(-4.67)MES(0)T(0)VS(-15.06)S(-15.06)GT(-15.06)QT(-20.07)T(-24.45)VQDDPEQFEVIK 9 3 1174.8278 -0.13383 0 0 0 0 0 0 0 0 2770 1891 52 52 94 110 1026 655 Mix4_InSol_TiO2_1 6239 1026 655 Mix4_InSol_TiO2_1 6239 Q9Y6D6 Q9Y6D6 Q9Y6D6 >sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens GN=ARFGEF1 PE=1 SV=2 0.809768 6.29076 0 0 0 0 0.809768 6.29076 0.0915633 55.855 0 0 1 S AETEKQSPPHGEA CK1;Proline-directed 0.05 0.0915633 55.855 _ACEVALEEIKAETEKQpSPPHGEAK_ ACEVALEEIKAET(0.19)EKQS(0.81)PPHGEAK ACEVALEEIKAET(-6.29)EKQS(6.29)PPHGEAK 17 3 911.093 0.33965 115970 0 0 0 0 0 115970 0 2771 1891 396 396 3754 4234 35475 21909 Mix4_TiO2_1_1 2592 35478 21912 Mix4_TiO2_Reinj_1_5 3540 Q9Y6D6 Q9Y6D6 Q9Y6D6 >sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens GN=ARFGEF1 PE=1 SV=2 0.638026 3.79418 0.638026 3.79418 3.91275E-05 97.601 0.629305 3.36896 9.8905E-13 137.06 0 0 1 S DDRLSVSSNDTQE CK2;NEK6 0.076 9.8905E-13 137.06 _LSVpSSNDTQESGNSSGPSPGAK_ LS(0.096)VS(0.638)S(0.266)NDTQESGNSSGPSPGAK LS(-8.24)VS(3.79)S(-3.79)NDT(-44.04)QES(-80.49)GNS(-96.08)S(-96.08)GPS(-96.08)PGAK 4 2 1093.4659 -0.58556 141460 0.24124 37985 0 0 103470 0 0 0 2772 1891 397 397 3754 4234 35476 21910 Mix4_TiO2_1_5 2918 35478 21912 Mix4_TiO2_Reinj_1_5 3540 Q9Y6D6 Q9Y6D6 Q9Y6D6 >sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens GN=ARFGEF1 PE=1 SV=2 0.734891 7.46192 0.734891 7.46192 3.91275E-05 97.601 0.365681 0 9.8905E-13 137.06 0 0 1 S DRLSVSSNDTQES CK1 0.081 9.8905E-13 137.06 _LSVSpSNDTQESGNSSGPSPGAK_ LS(0.132)VS(0.132)S(0.735)NDT(0.001)QESGNSSGPSPGAK LS(-7.46)VS(-7.46)S(7.46)NDT(-27.09)QES(-54.51)GNS(-97.6)S(-97.6)GPS(-97.6)PGAK 5 2 1093.4659 0.19891 30536 0.052076 30536 0 0 0 0 0 0 2773 1892 4 4 262 300;301 2566 1615 Mix4_TiO2_Reinj_1_4 6319 2560 1606 Mix4_InSol_TiO2_1 6734 Q9Y6E0-2 Q9Y6E0-2 Q9Y6E0-2 >sp|Q9Y6E0-2|STK24_HUMAN Isoform A of Serine/threonine-protein kinase 24 OS=Homo sapiens GN=STK24 0.999999 61.6768 0.999946 42.7025 0.00958052 73.527 0.993319 21.7224 0.699098 21.722 0.999999 61.6768 0.0003891 95.863 0.999997 54.6603 4.751E-09 131.07 0.999999 59.5127 1.26414E-05 100.4 1 S ___MAHSPVQSGL GSK3;Proline-directed 0.05 4.751E-09 131.07 _(ac)AHpSPVQSGLPGMQNLK_ AHS(1)PVQSGLPGMQNLK AHS(61.68)PVQS(-61.68)GLPGMQNLK 3 2 893.42131 1.1126 2163700 450410 16618 0 1104100 0 339570 252940 2774 1894 207 207 831;832;3488 940;942;3939 7827 4650 Mix4_TiO2_Reinj_1_4 6491 7793 4610 Mix4_TiO2_1_4 6005 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 1 78.301 1 109.54 3.66669E-31 196.21 0 0 1 78.301 1.00781E-25 180.99 0 0 1 100.287 4.0098E-06 100.29 1 134.92 7.03424E-11 134.92 1 S GEDFPASPQRRNT CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 3.66669E-31 196.21 _DFQEYVEPGEDFPApSPQRR_ DFQEYVEPGEDFPAS(1)PQRR DFQEY(-78.3)VEPGEDFPAS(78.3)PQRR 15 3 783.00574 -0.32033 19440000 201.03 4256200 0 0 11929000 0 1864700 1390500 2775 1894 510 510 2926;3171 3330;3599;3600 30097 18750 Mix4_TiO2_Reinj_1_4 4099 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.997763 27.4514 0.956481 13.9559 1.42096E-26 191.69 0.459537 0.0452948 1.00596E-15 147.21 0.997763 27.4514 1.07972E-21 171.88 0 0 0.88768 9.15062 6.52093E-16 150.53 0.981171 17.352 5.8464E-26 180.71 1 S RKPVTVSPTTPTS Proline-directed 0.05 1.42096E-26 191.69 _KPVTVpSPTTPTSPTEGEAS_ KPVTVS(0.998)PT(0.002)TPTSPTEGEAS KPVT(-48.45)VS(27.45)PT(-27.45)T(-44.56)PT(-34.04)S(-74.78)PT(-110.81)EGEAS(-123.26) 6 2 983.45627 0.18894 4976200 33.962 303870 0 0 3820300 0 427400 424610 2776 1894 516 516 2926;3171 3330;3599;3600 27950 17382 Mix4_InSol_TiO2_1 4385 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.860491 8.76933 0.833166 7.00015 1.42096E-26 191.69 0.321008 -3.23024 1.00596E-15 147.21 0.83236 6.9896 1.07972E-21 171.88 0 0 0.860491 8.76933 6.52093E-16 150.53 0.988735 20.4153 1.65599E-21 169.71 1 S SPTTPTSPTEGEA CK1;CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 1.42096E-26 191.69 _ITRKPVTVSPTTPTpSPTEGEAS_ ITRKPVTVSPTT(0.001)PT(0.024)S(0.86)PT(0.114)EGEAS(0.001) IT(-86.93)RKPVT(-86.93)VS(-68.15)PT(-46.34)T(-30.63)PT(-15.55)S(8.77)PT(-8.77)EGEAS(-32.01) 15 3 779.38422 0.3281 17763000 121.23 4924300 0 0 12240000 0 598690 0 2777 1894 523 523 2926;3171 3330;3599;3600 30081 18726 Mix4_InSol_Tio2_Reinj_3 2266 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.141488 0.477943 0.00631499 -20.4691 1.42096E-26 191.69 5.59395E-08 -70.8182 1.00596E-15 147.21 3.48551E-05 -44.2048 1.07972E-21 171.88 0 0 0.138623 -1.6818 6.52093E-16 150.53 0.141488 0.477943 5.8464E-26 180.71 1 S PTEGEAS______ 1.42096E-26 191.69 _KPVTVSPTTPTSPTEGEApS_ KPVT(0.122)VS(0.122)PT(0.122)T(0.122)PT(0.122)S(0.127)PT(0.122)EGEAS(0.141) KPVT(-0.64)VS(-0.64)PT(-0.64)T(-0.64)PT(-0.64)S(-0.48)PT(-0.64)EGEAS(0.48) 19 2 983.45627 0.8564 0 0 0 0 0 0 0 0 0 2778 1894 419 419 5852;5853 6674;6675 57728 35113 Mix4_InSol_Tio2_Reinj_1 4798 57728 35113 Mix4_InSol_Tio2_Reinj_1 4798 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.948403 12.6437 0.586909 1.52559 6.92792E-06 104.97 0 0 0 0 0.886283 11.9999 1.59348E-12 138.6 0.948403 12.6437 3.89477E-20 177.34 1 S VSSNVASVSPIPA CK1 0.143 3.89477E-20 177.34 _SVSSNVApSVSPIPAGSK_ SVSSNVAS(0.948)VS(0.052)PIPAGSK S(-97.79)VS(-87.13)S(-87.13)NVAS(12.64)VS(-12.64)PIPAGS(-101.95)K 8 2 833.90602 0.52702 550740 339080 0 0 0 0 131710 79948 2779 1894 421 421 5852;5853 6674;6675 57740 35117 Mix4_InSol_Tio2_Reinj_1 4549 57728 35113 Mix4_InSol_Tio2_Reinj_1 4798 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.983854 18.251 0.421979 -1.36068 6.92792E-06 104.97 0 0 0 0 0.405216 -1.6667 1.59348E-12 138.6 0.983854 18.251 3.89477E-20 177.34 1 S SNVASVSPIPAGS Proline-directed 0.05 3.89477E-20 177.34 _SVSSNVASVpSPIPAGSKK_ SVSSNVAS(0.001)VS(0.984)PIPAGS(0.015)KK S(-58.16)VS(-58.16)S(-47.25)NVAS(-28.45)VS(18.25)PIPAGS(-18.25)KK 10 2 897.9535 0.27133 28367 0 0 0 0 0 0 28367 2780 1895;1896 344;344 344 4629 5254 43874 26892 Mix4_TiO2_Reinj_1_4 5830 43874 26892 Mix4_TiO2_Reinj_1_4 5830 Q9Y6M4;Q9Y6M4-3;Q9Y6M4-2 Q9Y6M4;Q9Y6M4-3 Q9Y6M4-3 >sp|Q9Y6M4|KC1G3_HUMAN Casein kinase I isoform gamma-3 OS=Homo sapiens GN=CSNK1G3 PE=1 SV=2;>sp|Q9Y6M4-3|KC1G3_HUMAN Isoform 3 of Casein kinase I isoform gamma-3 OS=Homo sapiens GN=CSNK1G3;>sp|Q9Y6M4-2|KC1G3_HUMAN Isoform CSNK1G3L of Casein kinase I isofor 0.878954 8.61017 0.878954 8.61017 3.6476E-06 101.87 1 S QQDPALSSNREAH 3.6476E-06 101.87 _QLPTPVGAVQQDPALpSSNR_ QLPTPVGAVQQDPALS(0.879)S(0.121)NR QLPT(-101.87)PVGAVQQDPALS(8.61)S(-8.61)NR 16 3 686.67204 -0.081767 317940 4.5866 0 0 0 317940 0 0 0 2781 1895 413 413 5496 6258 53691 32816 Mix4_TiO2_Reinj_1_4 5477 53691 32816 Mix4_TiO2_Reinj_1_4 5477 Q9Y6M4 Q9Y6M4 Q9Y6M4 >sp|Q9Y6M4|KC1G3_HUMAN Casein kinase I isoform gamma-3 OS=Homo sapiens GN=CSNK1G3 PE=1 SV=2 0.999852 39.3997 0 0 0.999852 39.3997 0.113858 47.859 1 S DPTAGRSNAPITA CK1 0.143 0.113858 47.859 _pSNAPITAPTEVEVM(ox)DETK_ S(1)NAPITAPTEVEVMDETK S(39.4)NAPIT(-39.4)APT(-47.86)EVEVMDET(-47.86)K 1 2 1014.4476 -0.096626 96781 0 0 0 96781 0 0 0 2782 1896 365 365 4284 4875 40769 25092 Mix4_InSol_Tio2_Reinj_1 4659 40769 25092 Mix4_InSol_Tio2_Reinj_1 4659 Q9Y6M4-3 Q9Y6M4-3 Q9Y6M4-3 >sp|Q9Y6M4-3|KC1G3_HUMAN Isoform 3 of Casein kinase I isoform gamma-3 OS=Homo sapiens GN=CSNK1G3 0.447302 0 0 0 0.0269932 -14.9637 8.21218E-11 130.25 0.174784 -6.12678 4.55683E-16 145.45 0.447302 0 1.59705E-26 181.3 1 S SKNQVVSSTNGEL 1.59705E-26 181.3 _NQVVpSSTNGELNTDDPTAGR_ NQVVS(0.447)S(0.447)T(0.105)NGELNTDDPTAGR NQVVS(0)S(0)T(-6.28)NGELNT(-112.25)DDPT(-154.12)AGR 5 2 1077.9686 -0.94054 0 0 0 0 0 0 0 0 2783 1896 366 366 4284 4875 40768 25091 Mix4_InSol_TiO2_2 3502 40769 25092 Mix4_InSol_Tio2_Reinj_1 4659 Q9Y6M4-3 Q9Y6M4-3 Q9Y6M4-3 >sp|Q9Y6M4-3|KC1G3_HUMAN Isoform 3 of Casein kinase I isoform gamma-3 OS=Homo sapiens GN=CSNK1G3 0.716441 6.12678 0 0 0.126503 -8.25529 8.21218E-11 130.25 0.716441 6.12678 4.55683E-16 145.45 0.464082 0 1.59705E-26 181.3 1 S KNQVVSSTNGELN 1.59705E-26 181.3 _NQVVSpSTNGELNTDDPTAGR_ NQVVS(0.175)S(0.716)T(0.109)NGELNTDDPTAGR NQVVS(-6.13)S(6.13)T(-8.19)NGELNT(-51.1)DDPT(-67.89)AGR 6 2 1077.9686 -0.065123 34655 0 0 0 0 0 34655 0 2784 1897 857 857 624 719 5949 3484 Mix4_TiO2_Reinj_1_5 5959 5949 3484 Mix4_TiO2_Reinj_1_5 5959 Q9Y6Q9;Q9Y6Q9-5;Q9Y6Q9-3;Q9Y6Q9-2 Q9Y6Q9 Q9Y6Q9 >sp|Q9Y6Q9|NCOA3_HUMAN Nuclear receptor coactivator 3 OS=Homo sapiens GN=NCOA3 PE=1 SV=1;>sp|Q9Y6Q9-5|NCOA3_HUMAN Isoform 5 of Nuclear receptor coactivator 3 OS=Homo sapiens GN=NCOA3;>sp|Q9Y6Q9-3|NCOA3_HUMAN Isoform 3 of Nuclear receptor coactivator 3 OS=H 0.999999 60.0065 0.999998 58.0728 0.00192166 80.515 0.999999 60.0065 0.00123111 87.13 1 S PYNRAVSLDSPVS CAMK2 0.042 0.00123111 87.13 _AVpSLDSPVSVGSSPPVK_ AVS(1)LDSPVSVGSSPPVK AVS(60.01)LDS(-60.01)PVS(-73.88)VGS(-84.84)S(-87.13)PPVK 3 2 853.42404 0.26455 182760 56813 0 0 125950 0 0 0 2785 1898 431 431 4159;4160 4735;4736 39640 24457 Mix4_TiO2_Reinj_1_5 9004 39645 24463 Mix4_TiO2_Reinj_1_5 8801 Q9Y6R4;Q9Y6R4-2;Q9Y6R4-3;Q9Y6R4-4 Q9Y6R4 Q9Y6R4 >sp|Q9Y6R4|M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens GN=MAP3K4 PE=1 SV=2;>sp|Q9Y6R4-2|M3K4_HUMAN Isoform B of Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens GN=MAP3K4;>sp|Q9Y6R4-3|M3K4_HUMAN Isoform 3 of 1 143.101 1 129.529 5.9325E-09 129.53 0 0 1 143.101 4.60991E-21 158.63 1 S PVFEIPSPRPSKG CDK1;GSK3;Proline-directed 0.0057 4.60991E-21 158.63 _NLSDIGWPVFEIPpSPR_ NLSDIGWPVFEIPS(1)PR NLS(-143.1)DIGWPVFEIPS(143.1)PR 14 2 953.95858 0.39707 690060 142750 0 0 547310 0 0 0 2786 1898 435 435 4160 4736 39644 24461 Mix4_TiO2_Reinj_1_1 8460 39645 24463 Mix4_TiO2_Reinj_1_5 8801 Q9Y6R4;Q9Y6R4-2;Q9Y6R4-3;Q9Y6R4-4 Q9Y6R4 Q9Y6R4 >sp|Q9Y6R4|M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens GN=MAP3K4 PE=1 SV=2;>sp|Q9Y6R4-2|M3K4_HUMAN Isoform B of Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens GN=MAP3K4;>sp|Q9Y6R4-3|M3K4_HUMAN Isoform 3 of 0.559355 1.03598 0.277981 -2.03405 1.10131E-07 117.62 0 0 0.559355 1.03598 4.60991E-21 158.63 1 S IPSPRPSKGNEPE CK1;PKA 0.042 4.60991E-21 158.63 _NLSDIGWPVFEIPSPRPpSK_ NLSDIGWPVFEIPS(0.441)PRPS(0.559)K NLS(-83.21)DIGWPVFEIPS(-1.04)PRPS(1.04)K 18 3 740.36807 -0.1315 39755 0 0 0 39755 0 0 0 2787 1900 171 171 5909 6739 58282 35376 Mix4_TiO2_Reinj_1_6 4520 58282 35376 Mix4_TiO2_Reinj_1_6 4520 REV__A5PLN7;REV__A5PLN7-3;REV__A5PLN7-4;REV__A5PLN7-2 REV__A5PLN7 REV__A5PLN7 >sp|A5PLN7|F149A_HUMAN Protein FAM149A OS=Homo sapiens GN=FAM149A PE=2 SV=2;>sp|A5PLN7-3|F149A_HUMAN Isoform 3 of Protein FAM149A OS=Homo sapiens GN=FAM149A;>sp|A5PLN7-4|F149A_HUMAN Isoform 4 of Protein FAM149A OS=Homo sapiens GN=FAM149A;>sp|A5PLN7-2|F149A 0.999198 34.3698 0.999198 34.3698 0.14132 40.576 2 S VPKKTASPSLGHT Proline-directed 0.05 0.14132 40.576 _pTApSPSLGHTDSRAGR_ T(0.999)AS(0.999)PS(0.001)LGHTDSRAGR T(34.37)AS(34.37)PS(-34.37)LGHT(-40.58)DS(-40.58)RAGR 3 2 836.84564 1.4798 27463 0 0 0 27463 0 0 0 + 2788 1901 15 15 1466 1648 13703 8369 Mix4_TiO2_1_4 5808 13703 8369 Mix4_TiO2_1_4 5808 REV__O14730;REV__O14730-2 REV__O14730 REV__O14730 >sp|O14730|RIOK3_HUMAN Serine/threonine-protein kinase RIO3 OS=Homo sapiens GN=RIOK3 PE=1 SV=2;>sp|O14730-2|RIOK3_HUMAN Isoform 2 of Serine/threonine-protein kinase RIO3 OS=Homo sapiens GN=RIOK3 0.999948 42.8685 0.999948 42.8685 0.14392 42.868 1 S GDKDLFSAKRAGK 0.14392 42.868 _(ac)EDYLLPPDGDKDLFpSAK_ EDYLLPPDGDKDLFS(1)AK EDY(-42.87)LLPPDGDKDLFS(42.87)AK 15 2 1022.9612 -1.4801 73142 73142 0 0 0 0 0 0 + 2789 1902 421 421 941 1061 8943 5462 Mix4_TiO2_Reinj_1_2 4614 8942 5460 Mix4_TiO2_1_2 3863 REV__O14974-3 REV__O14974-3 REV__O14974-3 >sp|O14974-3|MYPT1_HUMAN Isoform Myosin phosphatase target subunit 1 variant 2 of Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens GN=PPP1R12A 0.995765 23.9161 0.968968 14.9524 0.120548 45.63 0.995765 23.9161 0.174456 40.122 1 S EAWRLNSTKSHYT CAMK2 0.042 0.120548 45.63 _DKEETSDEAWRLNpSTK_ DKEETSDEAWRLNS(0.996)T(0.004)K DKEET(-40.12)S(-40.12)DEAWRLNS(23.92)T(-23.92)K 14 2 994.93349 -0.501 811010 73745 0 0 737270 0 0 0 + 2790 1904 563 563 5752 6555 56561 34531 Mix4_TiO2_2_2 2922 56561 34531 Mix4_TiO2_2_2 2922 REV__O76039 REV__O76039 REV__O76039 >sp|O76039|CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1 0.981526 17.3838 0.906284 12.3134 0.480744 26.83 0.981526 17.3838 0.0478227 56.116 2 S PITDIYSRHSKQE CK1 0.143 0.0478227 56.116 _SSSQPITDIpYpSRHSK_ SSSQPIT(0.002)DIY(0.985)S(0.982)RHS(0.032)K S(-56.12)S(-56.12)S(-56.12)QPIT(-30.87)DIY(18.3)S(17.38)RHS(-17.38)K 11 2 933.39516 -2.4799 73903 34609 39294 0 0 0 0 0 + 2791 1905 179 179 6400 7322 64650 39657 Mix4_TiO2_Reinj_1_3 5063 64650 39657 Mix4_TiO2_Reinj_1_3 5063 REV__O94985;REV__O94985-2 REV__O94985 REV__O94985 >sp|O94985|CSTN1_HUMAN Calsyntenin-1 OS=Homo sapiens GN=CLSTN1 PE=1 SV=1;>sp|O94985-2|CSTN1_HUMAN Isoform Alcalpha1 of Calsyntenin-1 OS=Homo sapiens GN=CLSTN1 1 53.4108 1 53.4108 0.108069 53.411 1 S EKVFENSIRYGNL PLK1 0.033462 0.108069 53.411 _VFENpSIR_ VFENS(1)IR VFENS(53.41)IR 5 2 472.7155 -0.2646 131420 0 0 0 131420 0 0 0 + 2792 1908 115 115 2073 2348 19012 11580 Mix4_TiO2_2_2 6812 19015 11583 Mix4_TiO2_Reinj_1_4 7922 REV__P28907 REV__P28907 REV__P28907 >sp|P28907|CD38_HUMAN ADP-ribosyl cyclase 1 OS=Homo sapiens GN=CD38 PE=1 SV=2 0.553859 0.947779 0.131705 -7.58674 1.065 11.273 0.553859 0.947779 0.433837 31.037 0.295278 -3.77776 0.0973602 49.192 1 S VKTWFVSVPNNSC CK1 0.143 0.0973602 49.192 _FSVKTWFVpSVPNNSCK_ FSVKTWFVS(0.554)VPNNS(0.445)CK FS(-31.04)VKT(-31.04)WFVS(0.95)VPNNS(-0.95)CK 9 3 660.64102 0.49704 312110 0 312110 0 0 0 0 0 + 2793 1908 120 120 2073 2348 19017 11585 Mix4_TiO2_Reinj_1_6 6809 19015 11583 Mix4_TiO2_Reinj_1_4 7922 REV__P28907 REV__P28907 REV__P28907 >sp|P28907|CD38_HUMAN ADP-ribosyl cyclase 1 OS=Homo sapiens GN=CD38 PE=1 SV=2 0.994097 23.6023 0.755576 7.58674 1.065 11.273 0.445268 -0.947779 0.433837 31.037 0.994097 23.6023 0.0973602 49.192 1 S VSVPNNSCKRDWD 0.0973602 49.192 _FSVKTWFVSVPNNpSCK_ FS(0.001)VKT(0.001)WFVS(0.004)VPNNS(0.994)CK FS(-31.04)VKT(-31.04)WFVS(-23.6)VPNNS(23.6)CK 14 3 660.64102 0.28485 1060900 43617 0 0 1017200 0 0 0 + 2794 1910 255 255 3377 3818 31795 19696 Mix4_TiO2_Reinj_2_1 4736 31790 19691 Mix4_TiO2_2_4 6140 REV__P31323 REV__P31323 REV__P31323 >sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens GN=PRKAR2B PE=1 SV=3 1 15.6724 1 13.7665 1.02782 13.766 1 26.1396 0.0207586 63.462 1 29.433 0.143947 42.864 1 15.6724 0.96185 15.672 1 S MADLVQSMQEPDL CK2;NEK6 0.076 0.0207586 63.462 _LEFMADLVQpSMQEPDLK_ LEFMADLVQS(1)MQEPDLK LEFMADLVQS(15.67)MQEPDLK 10 2 1037.4673 0.70554 673400 48227 374120 0 228760 22300 0 0 + 2795 1911 370 370 4829 5482 46105 28180 Mix4_TiO2_Reinj_1_5 1922 46104 28178 Mix4_TiO2_Reinj_1_3 1817 REV__P31629 REV__P31629 REV__P31629 >sp|P31629|ZEP2_HUMAN Transcription factor HIVEP2 OS=Homo sapiens GN=HIVEP2 PE=1 SV=2 1 11.211 0 0 0 0 1 11.211 0.149755 46.096 1 S SLRRDPSLRRHPS CAMK2;CHK1;CHK1/2;PKC;PKD;PLK1 0.001764 0.149755 46.096 _RDPpSLRR_ RDPS(1)LRR RDPS(11.21)LRR 4 2 490.24529 0.054816 11204000 0 0 0 11204000 0 0 0 + 2796 1913 491 491 3824 4322 36320 22422 Mix4_TiO2_1_3 4093 36320 22422 Mix4_TiO2_1_3 4093 REV__P48643 REV__P48643 REV__P48643 >sp|P48643|TCPE_HUMAN T-complex protein 1 subunit epsilon OS=Homo sapiens GN=CCT5 PE=1 SV=1 0.499863 0 0.499863 0 0.131175 44.746 1 S LGNPGLSRTMTNA 0.131175 44.746 _MDLGNPGLpSRTMTNAVK_ MDLGNPGLS(0.5)RT(0.5)MTNAVK MDLGNPGLS(0)RT(0)MT(-32.61)NAVK 9 2 942.93901 0.1948 0 0 0 0 0 0 0 0 + 2797 1914 260 260 471 535 4430 2672 Mix4_TiO2_1_1 6434 4431 2673 Mix4_TiO2_Reinj_1_1 7139 REV__P51805 REV__P51805 REV__P51805 >sp|P51805|PLXA3_HUMAN Plexin-A3 OS=Homo sapiens GN=PLXNA3 PE=1 SV=2 0.198868 0 0.198868 0 0.96841 15.459 0 0 0.0176462 -15.1029 0.0638459 54.515 1 S IMPRARSLSDPSS CAMK2;CHK1;CK2 0.0228 0.0638459 54.515 _ARpSLSDPSSARTLLSER_ ARS(0.199)LS(0.199)DPS(0.199)S(0.199)ART(0.199)LLS(0.006)ER ARS(0)LS(0)DPS(0)S(0)ART(0)LLS(-15.46)ER 3 2 963.47566 0.81551 0 0 0 0 0 0 0 0 + 2798 1914 262 262 471 535 4430 2672 Mix4_TiO2_1_1 6434 4431 2673 Mix4_TiO2_Reinj_1_1 7139 REV__P51805 REV__P51805 REV__P51805 >sp|P51805|PLXA3_HUMAN Plexin-A3 OS=Homo sapiens GN=PLXNA3 PE=1 SV=2 0.198868 0 0.198868 0 0.96841 15.459 0 0 0.075192 -8.80771 0.0638459 54.515 1 S PRARSLSDPSSAR 14-3-3 binding;CAMK2;GSK3;PKA/AKT 0.0001701 0.0638459 54.515 _ARpSLSDPSSARTLLSER_ ARS(0.199)LS(0.199)DPS(0.199)S(0.199)ART(0.199)LLS(0.006)ER ARS(0)LS(0)DPS(0)S(0)ART(0)LLS(-15.46)ER 5 2 963.47566 0.81551 0 0 0 0 0 0 0 0 + 2799 1914 265 265 471 535 4430 2672 Mix4_TiO2_1_1 6434 4431 2673 Mix4_TiO2_Reinj_1_1 7139 REV__P51805 REV__P51805 REV__P51805 >sp|P51805|PLXA3_HUMAN Plexin-A3 OS=Homo sapiens GN=PLXNA3 PE=1 SV=2 0.198868 0 0.198868 0 0.96841 15.459 0 0 0.075192 -8.80771 0.0638459 54.515 1 S RSLSDPSSARTLL CK1 0.081 0.0638459 54.515 _ARpSLSDPSSARTLLSER_ ARS(0.199)LS(0.199)DPS(0.199)S(0.199)ART(0.199)LLS(0.006)ER ARS(0)LS(0)DPS(0)S(0)ART(0)LLS(-15.46)ER 8 2 963.47566 0.81551 0 0 0 0 0 0 0 0 + 2800 1914 266 266 471 535 4431 2673 Mix4_TiO2_Reinj_1_1 7139 4431 2673 Mix4_TiO2_Reinj_1_1 7139 REV__P51805 REV__P51805 REV__P51805 >sp|P51805|PLXA3_HUMAN Plexin-A3 OS=Homo sapiens GN=PLXNA3 PE=1 SV=2 0.571403 3.41026 0.198868 0 0.96841 15.459 0 0 0.571403 3.41026 0.0638459 54.515 1 S SLSDPSSARTLLS CK1 0.143 0.0638459 54.515 _ARSLSDPSpSARTLLSER_ ARS(0.018)LS(0.075)DPS(0.075)S(0.571)ART(0.261)LLSER ARS(-15.1)LS(-8.81)DPS(-8.81)S(3.41)ART(-3.41)LLS(-54.52)ER 9 2 963.47566 0.71087 436180 0 0 0 436180 0 0 0 + 2801 1915 318 318 3601 4059 33851 20843 Mix4_TiO2_1_1 3419 33854 20846 Mix4_TiO2_Reinj_1_1 3847 REV__Q06330;REV__Q06330-6;REV__Q06330-4;REV__Q06330-5;REV__Q06330-2;REV__Q06330-3 REV__Q06330 REV__Q06330 >sp|Q06330|SUH_HUMAN Recombining binding protein suppressor of hairless OS=Homo sapiens GN=RBPJ PE=1 SV=2;>sp|Q06330-6|SUH_HUMAN Isoform 6 of Recombining binding protein suppressor of hairless OS=Homo sapiens GN=RBPJ;>sp|Q06330-4|SUH_HUMAN Isoform 4 of Rec 0.534775 0.605073 0.534775 0.605073 1.01293 14.197 0.5 0 1.33375 4.9269 0.151896 -7.46904 0.120451 46.306 0.186638 -6.39284 0.67199 24.303 1 S LAKVTGSAICLDA 0.120451 46.306 _LNFLAKVTGpSAICLDAK_ LNFLAKVT(0.465)GS(0.535)AICLDAK LNFLAKVT(-0.61)GS(0.61)AICLDAK 10 2 950.98374 0.019099 330140 305770 24362 0 0 0 0 0 + 2802 1917 1173 1173 4453 5064 42318 26036 Mix4_TiO2_Reinj_1_4 2143 42318 26036 Mix4_TiO2_Reinj_1_4 2143 REV__Q13535;REV__Q13535-3;REV__Q13535-2 REV__Q13535 REV__Q13535 >sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3;>sp|Q13535-3|ATR_HUMAN Isoform 3 of Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR;>sp|Q13535-2|ATR_HUMAN Isoform 2 of Serine/threonine-protein kinase ATR 0.856899 7.773 0.856899 7.773 0.0348935 57.595 1 S IKKPVGSWDTKSQ 0.0348935 57.595 _PVGpSWDTKSQSKSR_ PVGS(0.857)WDT(0.143)KSQSKSR PVGS(7.77)WDT(-7.77)KS(-57.6)QS(-57.6)KS(-57.6)R 4 3 548.25768 -0.80867 419720 0 0 0 419720 0 0 0 + 2803 1918 1017 1017 3874 4395 36768 22653 Mix4_TiO2_1_3 2293 36768 22653 Mix4_TiO2_1_3 2293 REV__Q14203;REV__Q14203-2 REV__Q14203 REV__Q14203 >sp|Q14203|DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapiens GN=DCTN1 PE=1 SV=3;>sp|Q14203-2|DCTN1_HUMAN Isoform p135 of Dynactin subunit 1 OS=Homo sapiens GN=DCTN1 1 39.1089 1 39.1089 0.108062 39.109 0 0 1 S QEQKMKSWEQVQE 0.108062 39.109 _MKpSWEQVQELQK_ MKS(1)WEQVQELQK MKS(39.11)WEQVQELQK 3 2 807.3733 0.21957 32786 32786 0 0 0 0 0 0 + 2804 1923 894 894 1306 1473 12201 7474 Mix4_TiO2_Reinj_1_5 3642 12201 7474 Mix4_TiO2_Reinj_1_5 3642 REV__Q38SD2;REV__Q38SD2-3 REV__Q38SD2 REV__Q38SD2 >sp|Q38SD2|LRRK1_HUMAN Leucine-rich repeat serine/threonine-protein kinase 1 OS=Homo sapiens GN=LRRK1 PE=1 SV=2;>sp|Q38SD2-3|LRRK1_HUMAN Isoform 3 of Leucine-rich repeat serine/threonine-protein kinase 1 OS=Homo sapiens GN=LRRK1 1 40.297 1 33.049 0.263207 33.049 0 0 1 40.297 0.11804 40.297 0 0 0 0 0 0 1 S SFRDVESQCVKIM 0.11804 40.297 _DVEpSQCVKIMGGKK_ DVES(1)QCVKIMGGKK DVES(40.3)QCVKIMGGKK 4 2 829.88572 -0.57941 735070 79376 0 0 655690 0 0 0 + 2805 1925 46 46 6041 6890 59688 36216 Mix4_TiO2_1_4 4226 59690 36218 Mix4_TiO2_Reinj_1_4 4794 REV__Q6UXM1;REV__Q6UXM1-2 REV__Q6UXM1 REV__Q6UXM1 >sp|Q6UXM1|LRIG3_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 3 OS=Homo sapiens GN=LRIG3 PE=2 SV=1;>sp|Q6UXM1-2|LRIG3_HUMAN Isoform 2 of Leucine-rich repeats and immunoglobulin-like domains protein 3 OS=Homo sapiens GN=LRIG3 0.553876 0.940067 0.553876 0.940067 0.0621116 54.932 0.551062 0.893546 0.330597 36.02 0.550871 0.886839 0.035289 58.635 2 S GSDLDPSSHKALY NEK6 0.076 0.035289 58.635 _pTKEGDEESGSDLDPpSSHK_ T(1)KEGDEESGSDLDPS(0.554)S(0.446)HK T(54.93)KEGDEES(-43.48)GS(-43.34)DLDPS(0.94)S(-0.94)HK 15 2 1039.3854 0.36905 508060 94467 65031 0 348570 0 0 0 + 2806 1927 373 373 3389 3830 31929 19747 Mix4_TiO2_Reinj_1_4 3272 31927 19745 Mix4_TiO2_1_4 2711 REV__Q6ZWH5;REV__Q6ZWH5-5;REV__Q6ZWH5-6;REV__Q6ZWH5-7 REV__Q6ZWH5 REV__Q6ZWH5 >sp|Q6ZWH5|NEK10_HUMAN Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10 PE=2 SV=2;>sp|Q6ZWH5-5|NEK10_HUMAN Isoform 5 of Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10;>sp|Q6ZWH5-6|NEK10_HUMAN Isoform 6 of Serine/threonine-prot 0.975122 15.6249 0.999659 34.6646 0.0183594 65.368 0.999278 31.3056 0.0954962 43.201 0.975122 15.6249 0.0196132 64.18 3 S EKKLELSLQSTSL NEK6;PLK1 0.033462 0.0183594 65.368 _LELpSLQSpTpSLNDLK_ LELS(0.975)LQS(0.092)T(0.967)S(0.967)LNDLK LELS(15.62)LQS(-14.35)T(14.35)S(14.35)LNDLK 4 2 900.8771 -1.0133 444460 78245 158110 0 208110 0 0 0 + 2807 1927 378 378 3389 3830 31929 19747 Mix4_TiO2_Reinj_1_4 3272 31927 19745 Mix4_TiO2_1_4 2711 REV__Q6ZWH5;REV__Q6ZWH5-5;REV__Q6ZWH5-6;REV__Q6ZWH5-7 REV__Q6ZWH5 REV__Q6ZWH5 >sp|Q6ZWH5|NEK10_HUMAN Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10 PE=2 SV=2;>sp|Q6ZWH5-5|NEK10_HUMAN Isoform 5 of Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10;>sp|Q6ZWH5-6|NEK10_HUMAN Isoform 6 of Serine/threonine-prot 0.966667 14.3543 0.999688 35.0521 0.0183594 65.368 0.996133 24.0147 0.0954962 43.201 0.966667 14.3543 0.0196132 64.18 3 S LSLQSTSLNDLKY CK2 0.117 0.0183594 65.368 _LELpSLQSpTpSLNDLK_ LELS(0.975)LQS(0.092)T(0.967)S(0.967)LNDLK LELS(15.62)LQS(-14.35)T(14.35)S(14.35)LNDLK 9 2 900.8771 -1.0133 444460 78245 158110 0 208110 0 0 0 + 2808 1928 171 171 6703 7676 68007 41739 Mix4_TiO2_Reinj_1_4 6427 68007 41739 Mix4_TiO2_Reinj_1_4 6427 REV__Q7L5N7;REV__Q7L5N7-2 REV__Q7L5N7 REV__Q7L5N7 >sp|Q7L5N7|PCAT2_HUMAN Lysophosphatidylcholine acyltransferase 2 OS=Homo sapiens GN=LPCAT2 PE=1 SV=1;>sp|Q7L5N7-2|PCAT2_HUMAN Isoform 2 of Lysophosphatidylcholine acyltransferase 2 OS=Homo sapiens GN=LPCAT2 0.464918 0 0.464918 0 0.0964792 55.552 2 S GRIGKGSSSAISA 0.0964792 55.552 _pYAFEEIGRIGKGpSSSAISAYEDLK_ Y(1)AFEEIGRIGKGS(0.465)S(0.465)S(0.06)AIS(0.008)AY(0.002)EDLK Y(55.55)AFEEIGRIGKGS(0)S(0)S(-8.89)AIS(-17.43)AY(-24.43)EDLK 13 3 917.74866 0.18907 0 0 0 0 0 0 0 0 + 2809 1928 172 172 6703 7676 68007 41739 Mix4_TiO2_Reinj_1_4 6427 68007 41739 Mix4_TiO2_Reinj_1_4 6427 REV__Q7L5N7;REV__Q7L5N7-2 REV__Q7L5N7 REV__Q7L5N7 >sp|Q7L5N7|PCAT2_HUMAN Lysophosphatidylcholine acyltransferase 2 OS=Homo sapiens GN=LPCAT2 PE=1 SV=1;>sp|Q7L5N7-2|PCAT2_HUMAN Isoform 2 of Lysophosphatidylcholine acyltransferase 2 OS=Homo sapiens GN=LPCAT2 0.464918 0 0.464918 0 0.0964792 55.552 2 S RIGKGSSSAISAY CHK1;GSK3;PKD 0.020748 0.0964792 55.552 _pYAFEEIGRIGKGpSSSAISAYEDLK_ Y(1)AFEEIGRIGKGS(0.465)S(0.465)S(0.06)AIS(0.008)AY(0.002)EDLK Y(55.55)AFEEIGRIGKGS(0)S(0)S(-8.89)AIS(-17.43)AY(-24.43)EDLK 14 3 917.74866 0.18907 0 0 0 0 0 0 0 0 + 2810 1934 842 842 5103 5805 49319 30080 Mix4_TiO2_1_5 2344 49319 30080 Mix4_TiO2_1_5 2344 REV__Q92974;REV__Q92974-2;REV__Q92974-3 REV__Q92974 REV__Q92974 >sp|Q92974|ARHG2_HUMAN Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2 PE=1 SV=4;>sp|Q92974-2|ARHG2_HUMAN Isoform 2 of Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2;>sp|Q92974-3|ARHG2_HUMAN Isoform 3 of Rho guanine 0.999924 42.5465 0.999924 42.5465 0.144682 46.986 1 S SVKSALSLSRSRR CK1;GSK3 0.081 0.144682 46.986 _SALpSLSR_ SALS(1)LSR S(-46.99)ALS(42.55)LS(-42.55)R 4 2 407.19694 0.035744 83490 83490 0 0 0 0 0 0 + 2811 1935 204 204 6712 7685 68068 41766 Mix4_TiO2_Reinj_1_5 5077 68070 41768 Mix4_TiO2_Reinj_1_5 5545 REV__Q96NR3;REV__Q96NR3-2 REV__Q96NR3 REV__Q96NR3 >sp|Q96NR3|PTHD1_HUMAN Patched domain-containing protein 1 OS=Homo sapiens GN=PTCHD1 PE=2 SV=2;>sp|Q96NR3-2|PTHD1_HUMAN Isoform 2 of Patched domain-containing protein 1 OS=Homo sapiens GN=PTCHD1 0.721051 7.13472 0.598823 2.28867 0.40453 21.557 0 0 0.721051 7.13472 0.0618332 49.13 0 0 0.56589 3.92664 0.715676 10.948 0.145995 -7.19726 0.670067 12.482 1 S YDMYVFSPNFVIK ERK/MAPK;Proline-directed 0.0034 0.0618332 49.13 _YDMYVFpSPNFVIK_ Y(0.139)DMY(0.139)VFS(0.721)PNFVIK Y(-7.13)DMY(-7.13)VFS(7.13)PNFVIK 7 3 568.25774 -1.3014 2205400 262960 0 0 1721000 0 221430 0 + 2812 1936 664 664 5024 5715 48525 29669 Mix4_TiO2_Reinj_1_2 5546 48525 29669 Mix4_TiO2_Reinj_1_2 5546 REV__Q96PY6-3;REV__Q96PY6;REV__Q96PY6-2;REV__Q96PY6-4 REV__Q96PY6-3 REV__Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.999811 37.2255 0 0 0.999811 37.2255 0.106849 49.638 1 S IMDAEESGEQGES 0.106849 49.638 _RRIMDAEEpSGEQGESHNAK_ RRIMDAEES(1)GEQGESHNAK RRIMDAEES(37.23)GEQGES(-37.23)HNAK 9 2 1112.4761 0.8406 45099 0 0 0 45099 0 0 0 + 2813 1937 1088 1088 6789 7768 68905 42255 Mix4_TiO2_1_6 5151 68905 42255 Mix4_TiO2_1_6 5151 REV__Q9NYU2;REV__Q9NYU2-2 REV__Q9NYU2 REV__Q9NYU2 >sp|Q9NYU2|UGGG1_HUMAN UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens GN=UGGT1 PE=1 SV=3;>sp|Q9NYU2-2|UGGG1_HUMAN Isoform 2 of UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens GN=UGGT1 0.850453 7.54878 0.850453 7.54878 0.0393104 57.648 0 0 0 0 1 S PWSNRYSDVELNN CK1;CK2;PKA 0.042 0.0393104 57.648 _YpSDVELNNVWSIAPR_ Y(0.15)S(0.85)DVELNNVWSIAPR Y(-7.55)S(7.55)DVELNNVWS(-57.65)IAPR 2 2 921.92474 0.56729 8034.7 8034.7 0 0 0 0 0 0 + 2814 14 492 492 6375 7292 64397 39510 Mix4_TiO2_2_2 2550 64397 39510 Mix4_TiO2_2_2 2550 A8MUX0 A8MUX0 A8MUX0 >sp|A8MUX0|KR10D_HUMAN Putative keratin-associated protein 10-like ENSP00000375147 OS=Homo sapiens PE=3 SV=1 1 65.487 0.999984 47.936 0.0218568 62.938 1 65.487 0.00849903 74.644 0.999918 40.883 0.133754 40.883 1 T EAPCQPTEAKPIS 0.00849903 74.644 _VDVSEEAPCQPpTEAK_ VDVSEEAPCQPT(1)EAK VDVS(-65.49)EEAPCQPT(65.49)EAK 12 2 870.36332 0.15823 3316000 708640 101650 0 2505800 0 0 0 2815 20 49 49 908 1024;1025 8711 5331 Mix4_TiO2_Reinj_1_6 3912 8724 5333 Mix4_TiO2_Reinj_1_2 5093 CON__P02662 CON__P02662 CON__P02662 >P02662 SWISS-PROT:P02662 Alpha-S1-casein - Bos taurus (Bovine). P02662 0.910645 9.63378 0.59039 1.58751 2.47535E-12 144 0.521679 0 1.09379 10.427 0.910645 9.63378 3.85568E-16 169.35 2 T DIGSESTEDQAME CK1 0.081 3.85568E-16 169.35 _DIGSEpSpTEDQAM(ox)EDIK_ DIGS(0.179)ES(0.911)T(0.911)EDQAMEDIK DIGS(-9.63)ES(9.63)T(9.63)EDQAMEDIK 7 3 648.56701 0.28528 1170100 307930 11879 0 850290 0 0 0 + 2816 21 130 130 1754;1755 1975;1976;1977;1978 16171 9783 Mix4_TiO2_1_1 1429 16175 9787 Mix4_TiO2_Reinj_1_2 1894 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 0.465194 0 0.465194 0 0.0361639 54.865 0 0 0.301149 -6.6665 0.00159308 95.733 0 0 0.127466 -8.34013 0.0274796 57.323 0.20108 -7.66562 0.250056 27.607 1 T NREQLSTSEENSK CK2 0.117 0.000220067 116.32 _EQLSpTSEENSKK_ EQLS(0.069)T(0.465)S(0.465)EENSKK EQLS(-8.27)T(0)S(0)EENS(-31.9)KK 5 2 730.31924 0.39013 0 0 0 0 0 0 0 0 + 2817 21 144 144 3249;3250;6274;6275 3683;3684;7167;7168;7169;7170 62716 38163 Mix4_TiO2_Reinj_1_6 3561 62656 38130 Mix4_TiO2_Reinj_1_6 3873 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 0.960224 13.8275 0.945147 12.363 1.70608E-08 161.7 0.641991 2.53635 6.63996E-05 128.41 0.960224 13.8275 7.24542E-13 177.81 0.509973 0.173298 0.00293448 92.408 0.841574 9.78843 8.21794E-09 158.54 0.598251 1.73066 1.36365E-05 133.95 1 T TVDMESTEVFTKK 7.24542E-13 177.81 _TVDM(ox)ESpTEVFTKK_ TVDMES(0.04)T(0.96)EVFTKK T(-82.41)VDMES(-13.83)T(13.83)EVFT(-106.27)KK 7 2 805.8546 -0.21453 19868000 3529100 634560 0 14643000 37289 973230 51245 + 2818 21 148 148 3249;3250;6274;6275 3683;3684;7167;7168;7169;7170 62683 38148 Mix4_TiO2_Reinj_1_2 4548 62656 38130 Mix4_TiO2_Reinj_1_6 3873 CON__P02663 CON__P02663 CON__P02663 >P02663 SWISS-PROT:P02663 Alpha-S2-casein [Contains: Casocidin-1 - Bos taurus (Bovine). P02663 0.354014 0 0.0377174 -13.2216 1.70608E-08 161.7 0.00290472 -25.321 6.63996E-05 128.41 0.354014 0 7.24542E-13 177.81 0.0651618 -8.76095 0.00293448 92.408 0.0883586 -9.78843 8.21794E-09 158.54 0.121937 -5.27046 1.36365E-05 133.95 1 T ESTEVFTKKTKLT 7.24542E-13 177.81 _TVDMESpTEVFTKK_ T(0.146)VDMES(0.146)T(0.354)EVFT(0.354)KK T(-3.85)VDMES(-3.85)T(0)EVFT(0)KK 11 3 532.24052 0.20942 0 0 0 0 0 0 0 0 + 2819 29 314 314 2671 3040;3041 25033 15480 Mix4_TiO2_1_6 4509 25036 15483 Mix4_TiO2_Reinj_1_6 5220 CON__P12763 CON__P12763 CON__P12763 >P12763 SWISS-PROT:P12763 (Bos taurus) Alpha-2-HS-glycoprotein precursor P12763 0.475802 6.58129 0.475802 6.58129 1.09741 22.846 0.00215036 -22.8018 0.776796 29.399 0.351161 -2.17804 9.20144E-07 99.931 0.0143144 -15.2706 0.00011022 95.039 0 0 0 0 2 T HYDLRHTFSGVAS AURORA;NEK6;PKA 0.038874 9.20144E-07 99.931 _HpTFpSGVASVESSSGEAFHVGK_ HT(0.476)FS(0.483)GVAS(0.266)VES(0.258)S(0.258)S(0.258)GEAFHVGK HT(6.58)FS(7.17)GVAS(-6.58)VES(-7.17)S(-7.17)S(-7.17)GEAFHVGK 2 3 760.65051 0.26944 0 0 0 0 0 0 0 0 + 2820 40 142 142 6727 7700 68206 41809 Mix4_TiO2_Reinj_1_1 1879 68206 41809 Mix4_TiO2_Reinj_1_1 1879 CON__Q6IFU5;Q6A162 CON__Q6IFU5 CON__Q6IFU5 Cytokeratin-40;Keratin, type I cytoskeletal 40;Keratin-40;Type I hair keratin Ka36 KA36;KRT40 >Q6IFU5 TREMBL:Q6IFU5 Type I hair keratin KA36 - Homo sapiens (Human).;>sp|Q6A162|K1C40_HUMAN Keratin, type I cytoskeletal 40 OS=Homo sapiens GN=KRT40 PE=1 SV=2 Q6IFU5 0.998507 28.2521 0 0 0.998507 28.2521 0.0310385 54.259 1 T YQRYFNTIEDLQQ CK2;FHA1 Rad53p 0.059 0.0310385 54.259 _YFNpTIEDLQQK_ Y(0.001)FNT(0.999)IEDLQQK Y(-28.25)FNT(28.25)IEDLQQK 4 2 739.83179 -1.6755 52183 0 0 0 52183 0 0 0 + 2821 60 423 423 5296 6029 51420 31493 Mix4_TiO2_Reinj_1_3 8876 51421 31494 Mix4_TiO2_Reinj_1_4 8719 O00444;O00444-2;O00444-3 O00444 O00444 >sp|O00444|PLK4_HUMAN Serine/threonine-protein kinase PLK4 OS=Homo sapiens GN=PLK4 PE=1 SV=3;>sp|O00444-2|PLK4_HUMAN Isoform 2 of Serine/threonine-protein kinase PLK4 OS=Homo sapiens GN=PLK4;>sp|O00444-3|PLK4_HUMAN Isoform 3 of Serine/threonine-protein kin 0.718674 4.84036 0.0384379 -12.9986 1.12681E-11 128.87 0.718674 4.84036 4.37977E-26 173.11 0 0 0 0 1 T EERYSPTDNNANI 4.37977E-26 173.11 _SGGGENEERYSPpTDNNANIFNFFK_ SGGGENEERY(0.046)S(0.236)PT(0.719)DNNANIFNFFK S(-54.58)GGGENEERY(-11.98)S(-4.84)PT(4.84)DNNANIFNFFK 13 3 929.7276 0.41333 1571400 0 0 0 1571400 0 0 0 2822 64;1718;1892 168;172;172 172 3291;3292 3726;3727 31101 19275 Mix4_TiO2_Reinj_1_4 6932 31101 19275 Mix4_TiO2_Reinj_1_4 6932 O00506;Q9P289;Q9Y6E0-2;Q9Y6E0 O00506;Q9P289;Q9Y6E0-2 Q9Y6E0-2 >sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo sapiens GN=STK25 PE=1 SV=1;>sp|Q9P289|MST4_HUMAN Serine/threonine-protein kinase MST4 OS=Homo sapiens GN=MST4 PE=1 SV=2;>sp|Q9Y6E0-2|STK24_HUMAN Isoform A of Serine/threonine-protein kinase 0.994889 22.8928 0.991068 20.4515 1.23478E-06 116.4 0 0 0.994889 22.8928 6.16241E-16 165.41 1 T AGQLTDTQIKRNT NEK6 0.076 6.16241E-16 165.41 _LADFGVAGQLTDpTQIK_ LADFGVAGQLT(0.005)DT(0.995)QIK LADFGVAGQLT(-22.89)DT(22.89)QIK 13 2 878.92949 0.54978 822710 201040 0 0 621670 0 0 0 2823 64;1892 174;178 178 4970 5651;5652 47967 29327 Mix4_TiO2_1_4 7486 47973 29330 Mix4_TiO2_Reinj_1_4 8858 O00506;Q9Y6E0-2;Q9Y6E0 O00506;Q9Y6E0-2 Q9Y6E0-2 >sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo sapiens GN=STK25 PE=1 SV=1;>sp|Q9Y6E0-2|STK24_HUMAN Isoform A of Serine/threonine-protein kinase 24 OS=Homo sapiens GN=STK24;>sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo 0.999991 50.331 0.999991 50.331 0.000804936 91.189 0.880673 8.68077 6.17753E-09 120.55 1 T TQIKRNTFVGTPF AURORA;AURORA-A;PKA 0.006142092 6.17753E-09 120.55 _RNpTFVGTPFWM(ox)APEVIK_ RNT(1)FVGTPFWMAPEVIK RNT(50.33)FVGT(-50.33)PFWMAPEVIK 3 2 1045.0025 -0.043166 221490 88834 0 0 132650 0 0 0 2824 64;1892 178;182 182 4970 5651;5652 47969 29329 Mix4_TiO2_Reinj_1_4 8183 47973 29330 Mix4_TiO2_Reinj_1_4 8858 O00506;Q9Y6E0-2;Q9Y6E0 O00506;Q9Y6E0-2 Q9Y6E0-2 >sp|O00506|STK25_HUMAN Serine/threonine-protein kinase 25 OS=Homo sapiens GN=STK25 PE=1 SV=1;>sp|Q9Y6E0-2|STK24_HUMAN Isoform A of Serine/threonine-protein kinase 24 OS=Homo sapiens GN=STK24;>sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 OS=Homo 0.802282 6.0828 0.00361487 -24.4034 0.000804936 91.189 0.802282 6.0828 6.17753E-09 120.55 1 T RNTFVGTPFWMAP ERK/MAPK;Proline-directed 0.0034 6.17753E-09 120.55 _RNTFVGpTPFWM(ox)APEVIK_ RNT(0.198)FVGT(0.802)PFWMAPEVIK RNT(-6.08)FVGT(6.08)PFWMAPEVIK 7 3 697.00407 -0.35417 259500 0 0 0 259500 0 0 0 2825 65 315 315 631 726 6024 3519 Mix4_TiO2_Reinj_1_5 2689 6024 3519 Mix4_TiO2_Reinj_1_5 2689 O00512 O00512 O00512 >sp|O00512|BCL9_HUMAN B-cell CLL/lymphoma 9 protein OS=Homo sapiens GN=BCL9 PE=1 SV=4 0.999993 51.8611 0.999843 39.1345 0.0906827 50.612 0.999993 51.8611 0.0140896 69.201 1 T PNNRAVTPVSQGS CAMK2;FHA KAPP;Proline-directed 0.042 0.0140896 69.201 _AVpTPVSQGSNSSSADPK_ AVT(1)PVSQGSNSSSADPK AVT(51.86)PVS(-51.86)QGS(-69.2)NS(-69.2)S(-69.2)S(-69.2)ADPK 3 2 856.38036 1.3813 82137 15320 0 0 66818 0 0 0 2826 80 16 16 3062 3482 29177 18233 Mix4_TiO2_Reinj_1_4 2684 29179 18235 Mix4_TiO2_Reinj_1_5 2750 O14683 O14683 O14683 >sp|O14683|P5I11_HUMAN Tumor protein p53-inducible protein 11 OS=Homo sapiens GN=TP53I11 PE=2 SV=2 0.95206 12.9845 0.95206 12.9845 0.00126096 89.046 0.419484 -1.40011 0.156452 33.395 0.183728 -5.36915 0.675379 5.3692 1 T MKKHSQTDLVSRL 0.00126096 89.046 _KHSQpTDLVSR_ KHS(0.048)QT(0.952)DLVSR KHS(-12.98)QT(12.98)DLVS(-42.53)R 5 3 417.53448 1.4535 74455 0 0 0 74455 0 0 0 2827 83 330 330 6000 6840 59239 35992 Mix4_TiO2_1_4 7233 59239 35992 Mix4_TiO2_1_4 7233 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.545222 1.94879 0.545222 1.94879 1.08399E-09 152.06 0 0 0.462718 -0.391723 1.22952E-07 134.12 0 0 0 0 1 T GLSLWDTSPSYID FHA KAPP;NEK6 0.076 1.08399E-09 152.06 _TGLSLWDpTSPSYIDK_ TGLSLWDT(0.545)S(0.348)PS(0.107)YIDK T(-100.32)GLS(-94.42)LWDT(1.95)S(-1.95)PS(-7.09)Y(-44.48)IDK 8 2 881.9004 0.075906 187750 187750 0 0 0 0 0 0 2828 83 279 279 6642 7604;7605 67390 41400 Mix4_InSol_Tio2_Reinj_1 4268 67388 41397 Mix4_InSol_TiO2_1 4324 O14757 O14757 O14757 >sp|O14757|CHK1_HUMAN Serine/threonine-protein kinase Chk1 OS=Homo sapiens GN=CHEK1 PE=1 SV=1 0.402584 1.53357 0.0186759 -17.3988 0.121427 42.866 1.21085E-07 -66.151 0.00239705 83.188 0.0354991 -9.96879 0.00107337 92.162 0.000413049 -33.4758 3.69748E-07 127.34 0.402584 1.53357 0.00937782 73.874 1 T AKRPRVTSGGVSE PKA 0.042 3.69748E-07 127.34 _VpTSGGVSESPSGFSK_ VT(0.403)S(0.283)GGVS(0.264)ES(0.042)PS(0.009)GFSK VT(1.53)S(-1.53)GGVS(-1.84)ES(-9.85)PS(-16.43)GFS(-50.33)K 2 2 753.32961 -0.20662 0 0 0 0 0 0 0 0 2829 101 211 211 3549;3550 4003;4004 33506 20653 Mix4_TiO2_Reinj_1_6 3800 33506 20653 Mix4_TiO2_Reinj_1_6 3800 O15173 O15173 O15173 >sp|O15173|PGRC2_HUMAN Membrane-associated progesterone receptor component 2 OS=Homo sapiens GN=PGRMC2 PE=1 SV=1 0.98162 17.2774 0.813703 6.41963 0.00102908 86.337 0.98162 17.2774 2.0107E-10 133.05 1 T EEPSEYTDEEDTK CK1;CK2 0.081 2.0107E-10 133.05 _LLKPGEEPSEYpTDEEDTK_ LLKPGEEPSEY(0.018)T(0.982)DEEDTK LLKPGEEPS(-59.88)EY(-17.28)T(17.28)DEEDT(-53.3)K 12 3 720.64711 0.041913 452590 31300 0 0 421290 0 0 0 2830 103 141 141 5811;5812 6627;6628 57316 34913 Mix4_InSol_TiO2_1 3728 57292 34912 Mix4_TiO2_Reinj_1_5 2967 O15234 O15234 O15234 >sp|O15234|CASC3_HUMAN Protein CASC3 OS=Homo sapiens GN=CASC3 PE=1 SV=2 0.490251 0.877522 0.394001 0.698889 0.000554594 81.058 0 0 0.0431391 -13.1005 8.94264E-12 134.37 0.490251 0.877522 5.74479E-07 99.885 8.84328E-05 -40.4277 7.55368E-07 103.23 1 T KPDTKSTVTGERQ AURORA;AURORA-1 0.020748 8.94264E-12 134.37 _SpTVTGERQSGDGQESTEPVENKVGK_ S(0.401)T(0.49)VT(0.074)GERQS(0.035)GDGQESTEPVENKVGK S(-0.88)T(0.88)VT(-8.19)GERQS(-11.48)GDGQES(-52.85)T(-52.42)EPVENKVGK 2 3 900.41005 -0.069802 0 0 0 0 0 0 0 0 2831 103 143 143 5811;5812 6627;6628 57287 34906 Mix4_InSol_TiO2_1 3171 57292 34912 Mix4_TiO2_Reinj_1_5 2967 O15234 O15234 O15234 >sp|O15234|CASC3_HUMAN Protein CASC3 OS=Homo sapiens GN=CASC3 PE=1 SV=2 0.273064 0 0.112514 -8.82598 0.000554594 81.058 0 0 0.0431391 -13.1005 8.94264E-12 134.37 0.273064 0 5.74479E-07 99.885 0.0239744 -16.0964 7.55368E-07 103.23 1 T DTKSTVTGERQSG CK1 0.081 8.94264E-12 134.37 _SpTVTGERQSGDGQESTEPVENK_ S(0.217)T(0.273)VT(0.273)GERQS(0.237)GDGQESTEPVENK S(-1)T(0)VT(0)GERQS(-0.62)GDGQES(-44.29)T(-50.74)EPVENK 4 2 1208.019 0.13927 0 0 0 0 0 0 0 0 2832 113 463 463 174;4040 202;4602 1876 1262 Mix4_InSol_TiO2_1 4533 38186 23438 Mix4_TiO2_1_3 3558 O15427 O15427 O15427 >sp|O15427|MOT4_HUMAN Monocarboxylate transporter 4 OS=Homo sapiens GN=SLC16A3 PE=1 SV=1 0.499526 0 0.00545446 -22.6087 0.000741022 106.47 0 0 0.00639894 -21.9105 0.00516175 84.415 0.499526 0 0.0108992 71.911 0.132426 -7.02435 0.554908 28.089 1 T VVHTPETSV____ 0.000741022 106.47 _AEPEKNGEVVHTPEpTSV_ AEPEKNGEVVHT(0.001)PET(0.5)S(0.5)V AEPEKNGEVVHT(-27.22)PET(0)S(0)V 15 2 951.92768 1.343 0 0 0 0 0 0 0 0 2833 114 646 646 1055;2989 1186;3400 28526 17702 Mix4_TiO2_Reinj_1_1 4127 9953 6073 Mix4_TiO2_Reinj_1_5 4983 O15439;O15439-2 O15439 O15439 >sp|O15439|MRP4_HUMAN Multidrug resistance-associated protein 4 OS=Homo sapiens GN=ABCC4 PE=1 SV=3;>sp|O15439-2|MRP4_HUMAN Isoform 2 of Multidrug resistance-associated protein 4 OS=Homo sapiens GN=ABCC4 0.994041 23.8869 0 0 0.994041 23.8869 6.40334E-06 105.96 0 0 1 T QPPVPGTPTLRNR ERK/MAPK;FHA2 Rad53p;Proline-directed 0.0025 6.40334E-06 105.96 _KDNEESEQPPVPGpTPTLR_ KDNEES(0.002)EQPPVPGT(0.994)PT(0.004)LR KDNEES(-27.19)EQPPVPGT(23.89)PT(-23.89)LR 14 2 1037.4781 0.26747 382440 0 0 0 382440 0 0 0 2834 116 37 37 6189 7066 61276 37116 Mix4_InSol_TiO2_1 4274 61279 37119 Mix4_TiO2_Reinj_1_4 3926 O15530;O15530-3;Q6A1A2 O15530 O15530 >sp|O15530|PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens GN=PDPK1 PE=1 SV=1;>sp|O15530-3|PDPK1_HUMAN Isoform 3 of 3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens GN=PDPK1;>sp|Q6A1A2|PDPK2_HUMAN Putative 3-phosphoin 0.872213 8.35794 0.805751 6.32064 0.0150674 68.899 0.86732 8.16578 2.74588E-06 114.26 0.872213 8.35794 0.00166702 85.861 0.42841 -1.09245 0.0992446 48.879 1 T TQTESSTPPGIPG Polo box;Proline-directed 0.00405 2.74588E-06 114.26 _TQTESSpTPPGIPGGSR_ TQTESS(0.127)T(0.872)PPGIPGGSR T(-59.15)QT(-51.3)ES(-32.6)S(-8.36)T(8.36)PPGIPGGS(-67.41)R 7 2 826.3698 0.63747 507040 95290 0 0 308070 0 103680 0 2835 117 1462 1462 6250 7140;7141 62027 37561 Mix4_TiO2_1_1 4977 62028 37562 Mix4_TiO2_Reinj_1_1 5493 O43149;O43149-2 O43149 O43149 >sp|O43149|ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 PE=1 SV=6;>sp|O43149-2|ZZEF1_HUMAN Isoform 2 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Homo sapiens GN=ZZEF1 0.330613 0 0.330613 0 0.000629087 82.893 0 0 0.326411 0 0.0376351 73.966 0 0 0 0 1 T LNKRQRTSSVVEE CAMK2;PKA 0.003024 1.38507E-18 143.27 _pTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPK_ T(0.331)S(0.331)S(0.331)VVEEHFQAS(0.008)VSPTEAAPPATGDQSPGLGTQPK T(0)S(0)S(0)VVEEHFQAS(-16.11)VS(-37.12)PT(-57.85)EAAPPAT(-72.23)GDQS(-77.3)PGLGT(-81.76)QPK 1 3 1196.5561 0.27372 0 0 0 0 0 0 0 0 2836 138 616 616 5152 5866 49963 30546 Mix4_TiO2_Reinj_1_3 5516 49963 30546 Mix4_TiO2_Reinj_1_3 5516 O43663;O43663-2 O43663 O43663 >sp|O43663|PRC1_HUMAN Protein regulator of cytokinesis 1 OS=Homo sapiens GN=PRC1 PE=1 SV=2;>sp|O43663-2|PRC1_HUMAN Isoform 2 of Protein regulator of cytokinesis 1 OS=Homo sapiens GN=PRC1 0.841612 7.25389 0.840599 7.22099 5.74881E-16 176.81 0.841612 7.25389 4.98759E-16 179.25 0.840969 7.23299 9.68802E-13 174.42 0.838513 7.15371 1.82929E-09 148.87 1 T SGILNSTNIQS__ NEK6 0.076 4.98759E-16 179.25 _SDATSGILNSpTNIQS_ SDATSGILNS(0.158)T(0.842)NIQS S(-137.65)DAT(-130.11)S(-105.24)GILNS(-7.25)T(7.25)NIQS(-78.95) 11 2 794.34853 -0.14279 1198400 196180 0 0 583910 0 223020 195300 2837 139 306 306 3475 3922 32735 20280 Mix4_TiO2_2_4 5439 32736 20281 Mix4_TiO2_Reinj_1_5 3957 O43683 O43683 O43683 >sp|O43683|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens GN=BUB1 PE=1 SV=1 0.493351 0 0.427702 0.532394 0.758396 23.292 0.493351 0 1.01809 15.693 0.200343 -6.0113 0.000256003 95.787 1 T LHQVVETSHEDLP CK2 0.117 0.000256003 95.787 _LHQVVEpTSHEDLPASQER_ LHQVVET(0.493)S(0.493)HEDLPAS(0.013)QER LHQVVET(0)S(0)HEDLPAS(-15.69)QER 7 2 1077.9944 3.0011 0 0 0 0 0 0 0 0 2838 142 40 40 2844 3239;3240 27140 16970 Mix4_InSol_Tio2_Reinj_1 7960 27148 16980 Mix4_TiO2_Reinj_1_2 6306 O43741 O43741 O43741 >sp|O43741|AAKB2_HUMAN 5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens GN=PRKAB2 PE=1 SV=1 0.499995 0 0.121106 -8.60771 1.64879E-15 147.29 0 0 0.499875 0 8.50732E-21 157.68 0.0664122 -11.4791 0.00139517 81.897 0.499995 0 6.14373E-06 100.88 1 T KIMVGSTDDPSVF 8.50732E-21 157.68 _IMVGpSTDDPSVFSLPDSK_ IMVGS(0.5)T(0.5)DDPSVFSLPDSK IMVGS(0)T(0)DDPS(-46.73)VFS(-92.2)LPDS(-100.88)K 6 2 987.94194 0.32616 140970 0 0 0 0 0 0 140970 2839 150 201 201 6308 7208 63117 38470 Mix4_TiO2_1_4 7509 63117 38470 Mix4_TiO2_1_4 7509 P51817;O43930 P51817 P51817 >sp|P51817|PRKX_HUMAN Serine/threonine-protein kinase PRKX OS=Homo sapiens GN=PRKX PE=2 SV=1;>sp|O43930|PRKY_HUMAN Serine/threonine-protein kinase PRKY OS=Homo sapiens GN=PRKY PE=2 SV=1 0.892128 9.1752 0.892128 9.1752 1.53736E-21 170.18 0.5 0 0.000418966 91.743 1 T KKLVDRTWTLCGT FHA2 Rad53p;PLK1 0.033462 1.53736E-21 170.18 _pTWTLCGTPEYLAPEVIQSK_ T(0.892)WT(0.108)LCGTPEYLAPEVIQSK T(9.18)WT(-9.18)LCGT(-92.48)PEY(-140.76)LAPEVIQS(-170.18)K 1 2 1137.0316 0.38114 493060 143420 0 0 349640 0 0 0 2840 150 203 203 6308 7208 63116 38469 Mix4_TiO2_1_4 7506 63117 38470 Mix4_TiO2_1_4 7509 P51817;O43930 P51817 P51817 >sp|P51817|PRKX_HUMAN Serine/threonine-protein kinase PRKX OS=Homo sapiens GN=PRKX PE=2 SV=1;>sp|O43930|PRKY_HUMAN Serine/threonine-protein kinase PRKY OS=Homo sapiens GN=PRKY PE=2 SV=1 0.588058 1.54602 0.588058 1.54602 1.53736E-21 170.18 0.5 0 0.000418966 91.743 1 T LVDRTWTLCGTPE CAMK2;CHK1;PKD 0.020748 1.53736E-21 170.18 _TWpTLCGTPEYLAPEVIQSK_ T(0.412)WT(0.588)LCGTPEYLAPEVIQSK T(-1.55)WT(1.55)LCGT(-45.64)PEY(-67.29)LAPEVIQS(-139.84)K 3 3 758.35684 -0.0066504 410280 60638 0 0 349640 0 0 0 2841 156 211 211 2016 2284 18504 11207 Mix4_TiO2_1_3 7450 18504 11207 Mix4_TiO2_1_3 7450 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.998135 27.308 0.998135 27.308 1.29674E-06 105.16 0 0 1 T KDKFLQTFCGSPL 1.29674E-06 105.16 _FLQpTFCGSPLYASPEIVNGR_ FLQT(0.998)FCGS(0.002)PLYASPEIVNGR FLQT(27.31)FCGS(-27.31)PLY(-50.13)AS(-72.35)PEIVNGR 4 3 779.36422 0.65159 16890 16890 0 0 0 0 0 0 2842 156 414 414 5357 6099 52022 31854 Mix4_TiO2_Reinj_1_3 8095 52022 31854 Mix4_TiO2_Reinj_1_3 8095 O60285 O60285 O60285 >sp|O60285|NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1 0.59247 2.14548 0.590618 2.11827 5.10206E-05 97.473 0.59247 2.14548 1.18468E-05 98.552 1 T EHRSHSTGFIEGV CK1;FHA2 Rad53p 0.081 1.18468E-05 98.552 _SHSpTGFIEGVVGPALPSTFK_ S(0.046)HS(0.362)T(0.592)GFIEGVVGPALPSTFK S(-11.1)HS(-2.15)T(2.15)GFIEGVVGPALPS(-94.77)T(-98.55)FK 4 2 1056.0141 0.18634 330940 91013 0 0 239930 0 0 0 2843 166 529 529 3323 3759 31373 19448 Mix4_TiO2_Reinj_1_4 4851 31373 19448 Mix4_TiO2_Reinj_1_4 4851 O60504;O60504-2 O60504 O60504 >sp|O60504|VINEX_HUMAN Vinexin OS=Homo sapiens GN=SORBS3 PE=1 SV=1;>sp|O60504-2|VINEX_HUMAN Isoform Beta of Vinexin OS=Homo sapiens GN=SORBS3 0.726327 4.23901 0 0 0.726327 4.23901 0.00519024 78.973 1 T DGPQLPTSPRLTA 0.00519024 78.973 _LCDDGPQLPpTSPR_ LCDDGPQLPT(0.726)S(0.274)PR LCDDGPQLPT(4.24)S(-4.24)PR 10 2 768.33163 0.60114 64914 0 0 0 64914 0 0 0 2844 168 479 479 4553 5171 43116 26447 Mix4_TiO2_1_4 2839 43113 26443 Mix4_InSol_TiO2_1 3750 O60583;O60583-2 O60583 O60583 >sp|O60583|CCNT2_HUMAN Cyclin-T2 OS=Homo sapiens GN=CCNT2 PE=1 SV=2;>sp|O60583-2|CCNT2_HUMAN Isoform A of Cyclin-T2 OS=Homo sapiens GN=CCNT2 0.489447 0 0.489447 0 2.70062E-06 112.98 0.117945 -8.73152 9.97347E-07 116.23 0.0988628 -9.11324 6.66208E-09 119.21 0.00332317 -24.769 8.23056E-06 102.5 1 T ASSSSVTSPIKMK CK1;FHA2 Rad53p 0.081 6.66208E-09 119.21 _QGQSQAASSSSVpTSPIK_ QGQSQAASS(0.001)S(0.004)S(0.016)VT(0.489)S(0.489)PIK QGQS(-51.65)QAAS(-34.8)S(-27.96)S(-20.93)S(-14.8)VT(0)S(0)PIK 13 2 871.90146 0.1427 0 0 0 0 0 0 0 0 2845 177 594 594 6482 7415 65464 40130 Mix4_TiO2_Reinj_1_5 8456 65464 40130 Mix4_TiO2_Reinj_1_5 8456 O75122 O75122 O75122 >sp|O75122|CLAP2_HUMAN CLIP-associating protein 2 OS=Homo sapiens GN=CLASP2 PE=1 SV=2 0.5 0 0 0 0.5 0 0.0124034 70.623 1 T AMRVLNTGSDVEE CK2;FHA1 Rad53p 0.059 0.0124034 70.623 _VLNpTGSDVEEAVADALK_ VLNT(0.5)GS(0.5)DVEEAVADALK VLNT(0)GS(0)DVEEAVADALK 4 3 604.28719 -0.50384 22304 0 0 0 22304 0 0 0 2846 182 509 509 1729 1946 15878 9612 Mix4_TiO2_1_5 7208 15880 9614 Mix4_TiO2_Reinj_1_5 7893 O75175;O75175-2;O75175-3 O75175 O75175 >sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3 PE=1 SV=1;>sp|O75175-2|CNOT3_HUMAN Isoform 2 of CCR4-NOT transcription complex subunit 3 OS=Homo sapiens GN=CNOT3;>sp|O75175-3|CNOT3_HUMAN Isoform 3 of CCR4-NOT transc 0.302253 0 0.302253 0 0.0816137 77.496 0.286279 0 0.00592881 90.374 1 T NPPSSPTPSFSDA CK1;Proline-directed 0.05 0.00592881 90.374 _EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPpSSPTPSFSDAK_ EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPS(0.302)S(0.302)PT(0.302)PS(0.074)FS(0.019)DAK EPS(-60.23)AAAPT(-59.18)GAGGVAPGS(-45.06)GNNS(-45.06)GGPS(-45.06)LLVPLPVNPPS(0)S(0)PT(0)PS(-6.11)FS(-11.99)DAK 39 3 1431.0233 -0.96429 0 0 0 0 0 0 0 0 0 2847 199 244 244 300;2432 341;342;2756;2757 22825 14268 Mix4_TiO2_Reinj_1_5 1883 2805 1727 Mix4_TiO2_Reinj_1_5 1650 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.99986 40.4053 0.989117 19.7877 0.0510967 53.746 0.466824 0 0.557737 11.483 0.99986 40.4053 0.00118782 92.985 0.947438 13.1559 0.0496647 54.086 0.929031 13.4219 0.00875712 74.461 1 T RAKGSETPGATPG FHA KAPP;Proline-directed 0.05 0.00118782 92.985 _GSEpTPGATPGSK_ GSET(1)PGATPGSK GS(-43.12)ET(40.41)PGAT(-40.41)PGS(-79.84)K 4 2 584.74773 0.022128 941850 104300 0 0 596490 0 151670 89387 2848 199 278 278 2149;2944 2434;3351 19764 12077 Mix4_TiO2_Reinj_1_5 2069 19764 12077 Mix4_TiO2_Reinj_1_5 2069 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.993259 21.6991 0 0 0.993259 21.6991 3.82213E-06 101.1 1 T DTPGHATPGHGGA Proline-directed 0.05 3.82213E-06 101.1 _GDTPGHApTPGHGGATSSAR_ GDT(0.007)PGHAT(0.993)PGHGGATSSAR GDT(-21.7)PGHAT(21.7)PGHGGAT(-46.67)S(-54.94)S(-70.88)AR 8 2 907.3843 0.0046044 77146 0 0 0 77146 0 0 0 2849 199 267 267 2944 3351 28093 17451 Mix4_TiO2_Reinj_1_5 4382 28093 17451 Mix4_TiO2_Reinj_1_5 4382 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.980035 19.0204 0.980035 19.0204 0.00201022 83.39 1 T TPAGAATPGRGDT CDK1;CDK2;Proline-directed 0.0057 0.00201022 83.39 _IWDPTPSHTPAGAApTPGRGDTPGHATPGHGGATSSAR_ IWDPT(0.003)PS(0.003)HT(0.012)PAGAAT(0.98)PGRGDT(0.001)PGHATPGHGGATSSAR IWDPT(-24.59)PS(-24.95)HT(-19.02)PAGAAT(19.02)PGRGDT(-29.51)PGHAT(-43.58)PGHGGAT(-68.55)S(-65.77)S(-68.55)AR 15 4 907.41847 -0.30045 1005700 0 0 0 1005700 0 0 0 2850 199 223 223 3125;3748 3549;3550;4228 29754 18531 Mix4_TiO2_Reinj_1_5 5357 29754 18531 Mix4_TiO2_Reinj_1_5 5357 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 0.999772 39.6634 0.623195 4.94349 0.529956 30.088 0 0 0.999772 39.6634 0.0109076 71.322 0 0 0.158697 -2.17655 1.47911 2.1765 2 T SWDQAETPGHTPS Proline-directed 0.05 0.0109076 71.322 _KLSSWDQAEpTPGHpTPSLR_ KLSSWDQAET(1)PGHT(0.955)PS(0.045)LR KLS(-39.66)S(-39.66)WDQAET(39.66)PGHT(13.25)PS(-13.25)LR 10 3 723.98371 0.051517 459570 28994 0 0 430580 0 0 0 2851 199 211 211 5074;6673 5769;7641 67672 41541 Mix4_TiO2_1_5 3059 67674 41544 Mix4_TiO2_Reinj_1_5 3707 O75533 O75533 O75533 >sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3 1 63.1066 1 63.1066 1.60266E-06 120.63 0.998928 29.6914 0.000444463 97.473 0.999999 60.5963 1.60266E-06 120.63 0.96192 14.0248 0.04749 54.603 0.405784 1.3538 1.15382 1.3538 1 T DQTPGATPKKLSS CDK1;CDK2;Proline-directed 0.0057 1.60266E-06 120.63 _WDQTADQTPGApTPK_ WDQTADQTPGAT(1)PK WDQT(-120.63)ADQT(-63.11)PGAT(63.11)PK 12 2 798.34051 0.01448 1032400 71.06 131500 46712 0 834970 0 19227 0 2852 203 687 687 5724 6523;6524 56227 34382 Mix4_TiO2_Reinj_1_3 5984 56226 34380 Mix4_TiO2_1_3 5238 O75676;O75676-2 O75676 O75676 >sp|O75676|KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 PE=1 SV=1;>sp|O75676-2|KS6A4_HUMAN Isoform 2 of Ribosomal protein S6 kinase alpha-4 OS=Homo sapiens GN=RPS6KA4 0.999623 31.3234 0.991307 17.5602 2.99461E-06 104.8 0 0 0.999623 31.3234 0.00101638 81.539 0.725432 6.8983 0.0459289 57.106 0.33838 0 0.412676 34.864 2 T SSPPLRTPDVLES Proline-directed 0.05 2.99461E-06 104.8 _SpSPPLRpTPDVLESSGPAVR_ S(0.489)S(0.511)PPLRT(1)PDVLESSGPAVR S(-0.19)S(0.19)PPLRT(31.32)PDVLES(-81.54)S(-81.54)GPAVR 7 3 708.99573 -0.080406 783340 171230 0 0 612100 0 0 0 2853 205 1741 1741 5466 6220 53323 32584 Mix4_InSol_TiO2_2 2643 53323 32584 Mix4_InSol_TiO2_2 2643 O75691 O75691 O75691 >sp|O75691|UTP20_HUMAN Small subunit processome component 20 homolog OS=Homo sapiens GN=UTP20 PE=1 SV=3 0.999999 62.1251 0 0 0 0 0 0 0.999999 62.1251 0.000571892 80.503 0.855172 14.7017 1.41586 18.288 1 T DNGQPGTPDPADS ERK/MAPK;Proline-directed 0.0025 0.000571892 80.503 _SLSDNGQPGpTPDPADSGGTSAK_ SLSDNGQPGT(1)PDPADSGGTSAK S(-69.5)LS(-69.01)DNGQPGT(62.13)PDPADS(-62.13)GGT(-68.01)S(-68.01)AK 10 2 1069.9473 -1.7249 592780 0 0 0 0 0 360470 232310 2854 210 41 41 2280 2578 20996 12865 Mix4_TiO2_1_4 7092 20997 12866 Mix4_TiO2_Reinj_1_4 7706 O75821 O75821 O75821 >sp|O75821|EIF3G_HUMAN Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens GN=EIF3G PE=1 SV=2 0.499198 0 0.499198 0 7.16143E-12 130.15 0.474294 0 8.42139E-20 156.54 1 T PLATGDTSPEPEL CK2 0.117 8.42139E-20 156.54 _GIPLATGDpTSPEPELLPGAPLPPPK_ GIPLAT(0.002)GDT(0.499)S(0.499)PEPELLPGAPLPPPK GIPLAT(-24.93)GDT(0)S(0)PEPELLPGAPLPPPK 9 3 848.77142 0.6631 0 0 0 0 0 0 0 0 2855 218 358 358 572 656 5420 3242 Mix4_TiO2_1_3 6471 5421 3243 Mix4_TiO2_1_4 6487 O76021 O76021 O76021 >sp|O76021|RL1D1_HUMAN Ribosomal L1 domain-containing protein 1 OS=Homo sapiens GN=RSL1D1 PE=1 SV=3 0.89216 9.17664 0.89216 9.17664 5.94941E-06 106.82 0.197057 -6.10093 0.00363903 78.158 0.595125 1.67287 0.283196 36.899 0.0392938 -13.8827 0.683595 23.953 1 T KAQVKATNESEDE FHA KAPP 0.155 5.94941E-06 106.82 _ApTNESEDEIPQLVPIGK_ AT(0.892)NES(0.108)EDEIPQLVPIGK AT(9.18)NES(-9.18)EDEIPQLVPIGK 2 2 960.45353 0.87392 199990 159430 0 0 0 0 40560 0 2856 223 459 459 520 586;587 4800 2897 Mix4_InSol_Tio2_Reinj_2 3920 4815 2919 Mix4_TiO2_Reinj_1_5 4972 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.396684 1.24765 0.0422148 -11.8566 2.29616E-15 143.61 0.0010909 -29.3986 0.0917882 50.885 0.383717 -1.53619 2.02416E-15 145.15 0 0 0.0104126 -19.0853 2.43539E-06 111.26 0.396684 1.24765 6.69842E-10 122.91 1 T NSSALETLGGEKL 7.21566E-21 160.45 _ASQSRPNSSALEpTLGGEK_ AS(0.023)QS(0.023)RPNS(0.298)S(0.259)ALET(0.397)LGGEK AS(-12.28)QS(-12.28)RPNS(-1.25)S(-1.86)ALET(1.25)LGGEK 13 2 956.44403 0.13253 0 0 0 0 0 0 0 0 0 2857 223 952 952 3713;3714 4186;4188 35001 21679 Mix4_InSol_TiO2_2 2424 35000 21677 Mix4_InSol_TiO2_1 3403 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.978235 16.5318 0.742017 4.60375 4.48952E-16 180.84 0.553391 0.974183 3.69829E-16 183.37 0.743663 4.65376 4.65341E-30 221.14 0.977433 17.9369 0.00471803 77.958 0.978235 16.5318 1.86617E-30 228.71 0.783158 7.9681 4.48952E-16 180.84 1 T ECPNPSTPSKAAK CDK1;CDK2;ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 1.86617E-30 228.71 _LSEEAECPNPSpTPSK_ LSEEAECPNPS(0.022)T(0.978)PSK LS(-159.49)EEAECPNPS(-16.53)T(16.53)PS(-45.95)K 12 2 863.3555 -0.22774 8000100 17.606 191810 507620 0 286520 26933 5911100 1076200 2858 223 185 185 4141;4142 4716;4717 39509 24386 Mix4_TiO2_Reinj_1_5 2758 39486 24353 Mix4_InSol_Tio2_Reinj_1 3248 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 1 26.8176 1 78.8841 0.0665461 80.808 1 82.7085 0.0617432 82.709 1 26.8176 0.0286744 95.791 1 46.5711 0.147047 46.571 1 79.6494 0.0665462 80.808 1 76.6451 0.0202651 99.538 1 T SAKNLKTLQKRDS 0.0202651 99.538 _NLKpTLQKR_ NLKT(1)LQKR NLKT(26.82)LQKR 4 2 540.7999 0.3082 41022000 1322000 328640 0 32362000 65139 4083900 2860800 2859 223 195 195 4837 5491;5492;5494;5495 46215 28247 Mix4_TiO2_Reinj_1_5 8962 46215 28247 Mix4_TiO2_Reinj_1_5 8962 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.891889 9.16803 0.214285 -4.74681 0.000143742 94.244 0.891889 9.16803 9.58652E-17 142.66 1 T RDSFIGTPYWMAP Proline-directed 0.05 9.58652E-17 142.66 _RDSFIGpTPYWMAPEVVMCETMK_ RDS(0.108)FIGT(0.892)PYWMAPEVVMCETMK RDS(-9.17)FIGT(9.17)PY(-39.97)WMAPEVVMCET(-138.02)MK 7 3 910.06082 -1.2945 651450 0.37605 0 0 0 651450 0 0 0 2860 223 390 390 5463 6217 53315 32577 Mix4_InSol_Tio2_Reinj_1 7352 53316 32578 Mix4_TiO2_Reinj_1_5 6825 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.381258 0 0 0 0.00505595 -22.4254 0.000264221 84.003 0.0171064 -16.2702 0.277015 50.343 0.381258 0 1.4839 26.392 1 T GDRSLQTTSPPVV CK1 0.081 0.000264221 84.003 _SLQpTTSPPVVAPGNENGLAVPVPLRK_ S(0.044)LQT(0.381)T(0.381)S(0.194)PPVVAPGNENGLAVPVPLRK S(-9.42)LQT(0)T(0)S(-2.94)PPVVAPGNENGLAVPVPLRK 4 3 907.81602 -0.23955 0 0 0 0 0 0 0 0 2861 223 391 391 5463 6217 53315 32577 Mix4_InSol_Tio2_Reinj_1 7352 53316 32578 Mix4_TiO2_Reinj_1_5 6825 O94804 O94804 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 OS=Homo sapiens GN=STK10 PE=1 SV=1 0.381258 0 0 0 0.11094 -9.0125 0.000264221 84.003 0.256936 -4.5035 0.277015 50.343 0.381258 0 1.4839 26.392 1 T DRSLQTTSPPVVA NEK6 0.076 0.000264221 84.003 _SLQpTTSPPVVAPGNENGLAVPVPLRK_ S(0.044)LQT(0.381)T(0.381)S(0.194)PPVVAPGNENGLAVPVPLRK S(-9.42)LQT(0)T(0)S(-2.94)PPVVAPGNENGLAVPVPLRK 5 3 907.81602 -0.23955 0 0 0 0 0 0 0 0 2862 224 34 34 5999 6839 59235 35990 Mix4_InSol_Tio2_Reinj_2 5007 59230 35985 Mix4_InSol_TiO2_1 6881 O94806;O94806-2 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 0.231026 0 0 0 0.0560811 -10.1011 0.00666525 72.37 0.231026 0 0.00700182 71.975 1 T PCSSPKTGLSARL CK1;FHA KAPP 0.081 0.00666525 72.37 _pTGLSARLSNGSFSAPSLTNSR_ T(0.231)GLS(0.231)ARLS(0.231)NGS(0.231)FS(0.019)APS(0.019)LT(0.019)NS(0.019)R T(0)GLS(0)ARLS(0)NGS(0)FS(-10.85)APS(-10.85)LT(-10.85)NS(-10.85)R 1 3 735.02162 0.86071 0 0 0 0 0 0 0 0 2863 224 389 389 6033 6881;6882 59631 36185 Mix4_InSol_Tio2_Reinj_1 6631 59633 36189 Mix4_TiO2_Reinj_1_5 6302 O94806;O94806-2;Q15139 O94806 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3 PE=1 SV=1;>sp|O94806-2|KPCD3_HUMAN Isoform 2 of Serine/threonine-protein kinase D3 OS=Homo sapiens GN=PRKD3;>sp|Q15139|KPCD1_HUMAN Serine/threonine-protein kinase D1 OS=Homo 0.488781 0 0.0955752 -9.76027 0.00115151 93.228 0.0798458 -10.616 5.47269E-07 131.74 5.52916E-06 -51.7626 0.0413215 56.068 0.488781 0 0.0749211 48.088 1 T DEEAVKTISPSTS 5.47269E-07 131.74 _pTISPSTSNNIPLMR_ T(0.489)IS(0.489)PS(0.019)T(0.003)S(0.001)NNIPLMR T(0)IS(0)PS(-14.15)T(-22.13)S(-28.75)NNIPLMR 1 2 805.88403 0.30927 0 0 0 0 0 0 0 0 2864 229 97 97 5794 6600 57083 34820 Mix4_InSol_Tio2_Reinj_1 4797 57083 34820 Mix4_InSol_Tio2_Reinj_1 4797 O94901;O94901-5;O94901-3;O94901-2 O94901 O94901 >sp|O94901|SUN1_HUMAN SUN domain-containing protein 1 OS=Homo sapiens GN=SUN1 PE=1 SV=3;>sp|O94901-5|SUN1_HUMAN Isoform 5 of SUN domain-containing protein 1 OS=Homo sapiens GN=SUN1;>sp|O94901-3|SUN1_HUMAN Isoform 3 of SUN domain-containing protein 1 OS=Hom 0.577917 1.36486 0.524706 0.999867 0.737684 14.299 0.577917 1.36486 0.0207744 63.08 1 T TKQRRSTNKSAFS CAMK2;FHA KAPP;PKA 0.004788 0.0207744 63.08 _SpTNKSAFSINHVSR_ S(0.422)T(0.578)NKSAFSINHVSR S(-1.36)T(1.36)NKS(-45.06)AFS(-63.08)INHVS(-63.08)R 2 3 543.25779 0.063009 224760 0 0 0 0 0 158760 66006 2865 231 1915 1915 3227;5785 3659;6591 56980 34748 Mix4_InSol_TiO2_1 7633 30556 18999 Mix4_TiO2_1_1 5508 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.552345 0.916507 0.499665 0 2.1074E-08 117.09 0.49716 0 0.250353 49.369 0 0 0.552345 0.916507 0.000276208 87.162 0.517791 0.836679 0.000320367 85.293 1 T AANRKSTGQLNLS CAMK2;FHA2 Rad53p;PKA 0.004788 2.1074E-08 117.09 _SpTGQLNLSTSPINSSSYLGYNSNAR_ S(0.447)T(0.552)GQLNLSTSPINSSSYLGYNSNAR S(-0.92)T(0.92)GQLNLS(-35.11)T(-35.11)S(-40.03)PINS(-62.31)S(-62.31)S(-75.78)Y(-82.82)LGY(-87.16)NS(-87.16)NAR 2 3 904.41513 -0.14487 403590 0 0 0 0 0 206610 196970 2866 231 1959 1959 5032;5042;5534 5723;5734;5735;6304;6305 54137 33137 Mix4_TiO2_Reinj_1_1 5392 54137 33137 Mix4_TiO2_Reinj_1_1 5392 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.99724 25.5791 0.992622 21.2883 0.00129389 89.67 0.0725663 -11.0655 0.476304 13.967 0.99724 25.5791 0.00129389 89.67 0 0 0.88561 8.88855 0.00255261 85.052 0.983004 17.622 0.00436907 68.382 1 T DRRRSNTLDIMDG CAMK2;FHA2 Rad53p;PKA/AKT 0.001764 0.00129389 89.67 _SNpTLDIMDGR_ S(0.003)NT(0.997)LDIMDGR S(-25.58)NT(25.58)LDIMDGR 3 2 601.24958 0.16803 827560 155760 0 0 264270 0 161570 245960 2867 231 2270 2270 6311 7211 63141 38484 Mix4_TiO2_Reinj_1_1 5114 63136 38479 Mix4_InSol_TiO2_1 6028 O94915 O94915 O94915 >sp|O94915|FRYL_HUMAN Protein furry homolog-like OS=Homo sapiens GN=FRYL PE=1 SV=2 0.978926 16.7394 0.80686 6.30943 6.35418E-06 116.92 0 0 0.978926 16.7394 2.65724E-09 145.32 0 0 0.280571 -3.21546 2.59758E-09 145.58 0.53802 1.31164 7.25658E-08 135.5 1 T KTYGGDTGSPEIS 2.59758E-09 145.58 _TYGGDpTGSPEISFTK_ TYGGDT(0.979)GS(0.021)PEISFTK T(-101.69)Y(-138.64)GGDT(16.74)GS(-16.74)PEIS(-35.01)FT(-45.92)K 6 2 820.348 0.19803 1000700 164100 0 0 663420 0 0 173230 2868 242 39 39 177 205 1891 1269 Mix4_TiO2_1_6 4426 1894 1272 Mix4_TiO2_Reinj_1_6 5054 O95197;O95197-2;O95197-4;O95197-5;O95197-3 O95197 O95197 >sp|O95197|RTN3_HUMAN Reticulon-3 OS=Homo sapiens GN=RTN3 PE=1 SV=2;>sp|O95197-2|RTN3_HUMAN Isoform A3b of Reticulon-3 OS=Homo sapiens GN=RTN3;>sp|O95197-4|RTN3_HUMAN Isoform A2 of Reticulon-3 OS=Homo sapiens GN=RTN3;>sp|O95197-5|RTN3_HUMAN Isoform 5 of Re 0.352237 0.365011 0.352237 0.365011 0.749592 56.084 0.0125685 -18.947 1.6584E-06 107.16 1 T ACPALGTKSCSSS 1.6584E-06 107.16 _(ac)AEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGpTK_ AEPSAATQSHSISSSSFGAEPS(0.324)APGGGGS(0.324)PGACPALGT(0.352)K AEPS(-47.83)AAT(-46.47)QS(-46.47)HS(-47.83)IS(-46.6)S(-47.83)S(-46.32)S(-41.07)FGAEPS(-0.37)APGGGGS(-0.37)PGACPALGT(0.37)K 38 4 923.90972 0.56041 0 0 0 0 0 0 0 0 0 2869 252 181 181 5711 6508 56095 34316 Mix4_TiO2_1_4 1447 56092 34311 Mix4_InSol_TiO2_1 2166 O95429 O95429 O95429 >sp|O95429|BAG4_HUMAN BAG family molecular chaperone regulator 4 OS=Homo sapiens GN=BAG4 PE=1 SV=1 0.588381 2.75277 0.588381 2.75277 0.0552436 47.08 0.378541 -1.96476 0.0211426 57.193 0.203935 -2.58228 0.00937969 63.945 0.488804 3.38134 0.149761 34.63 1 T SSGNSPTPVSRWI FHA KAPP;Proline-directed 0.05 0.00937969 63.945 _SSGNSPpTPVSR_ S(0.042)S(0.058)GNS(0.312)PT(0.588)PVSR S(-11.48)S(-10.09)GNS(-2.75)PT(2.75)PVS(-45.06)R 7 2 584.75334 1.3411 24714 24714 0 0 0 0 0 0 2870 258 31 31 1810;6334;6361;6362 2042;7241;7242;7276;7278 64234 39413 Mix4_TiO2_Reinj_1_1 5798 64210 39400 Mix4_TiO2_Reinj_1_1 1478 O95674 O95674 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 2 OS=Homo sapiens GN=CDS2 PE=1 SV=1 0.97124 16.2609 0.39369 0 1.269E-05 139.29 0 0 0.97124 16.2609 5.55317E-06 149.07 0 0 0.0217973 -13.4865 1.39444 33.285 0 0 1 T AKVDGETASDSES CK2;FHA1 Rad53p 0.059 5.55317E-06 149.07 _VDGEpTASDSESRAESAPLPVSADDTPEVLNR_ VDGET(0.971)AS(0.023)DS(0.005)ES(0.001)RAESAPLPVSADDTPEVLNR VDGET(16.26)AS(-16.26)DS(-23.13)ES(-29.81)RAES(-43.63)APLPVS(-105.54)ADDT(-109.52)PEVLNR 5 3 1098.8264 0.36874 1735300 0.61616 0 0 0 1735300 0 0 0 2871 266;1237;1772 181;181;181 181 3783 4275 35924 22246 Mix4_TiO2_Reinj_1_5 6708 35924 22246 Mix4_TiO2_Reinj_1_5 6708 O95819-3;O95819-5;O95819;O95819-2;O95819-4;Q8N4C8;Q8N4C8-3;Q8N4C8-2;Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 O95819-3;Q8N4C8;Q9UKE5 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.999985 48.3375 0 0 0.999985 48.3375 0.0167682 67.465 0 0 0 0 0 0 1 T SAQLDRTVGRRNT NEK6;PLK1 0.033462 0.0167682 67.465 _LVDFGVSAQLDRpTVGR_ LVDFGVSAQLDRT(1)VGR LVDFGVS(-48.34)AQLDRT(48.34)VGR 13 3 604.97165 -0.33171 1098800 0 0 0 1098800 0 0 0 2872 266 926 926 4760 5407 45379 27750 Mix4_TiO2_Reinj_1_5 1895 45380 27751 Mix4_TiO2_Reinj_1_5 2362 O95819-3;O95819-5;O95819;O95819-2;O95819-4 O95819-3 O95819-3 >sp|O95819-3|M4K4_HUMAN Isoform 3 of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819-5|M4K4_HUMAN Isoform HGK-L of Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4;>sp|O95819|M4K 0.327902 0 1.65924E-05 -47.7003 0.044788 50.181 0 0 0.327902 0 0.00624829 71.649 0 0 0.00031396 -34.9235 0.123514 36.877 0.000674673 -31.0796 0.191252 31.08 1 T TQSASSTLQKHKS 0.00624829 71.649 _QTQSApSSTLQK_ QT(0.008)QS(0.008)AS(0.328)S(0.328)T(0.328)LQK QT(-16.22)QS(-15.89)AS(0)S(0)T(0)LQK 8 2 629.78738 -0.1477 0 0 0 0 0 0 0 0 2873 268 246 246 5859 6681 57810 35154 Mix4_TiO2_2_2 2508 57811 35157 Mix4_TiO2_Reinj_1_5 3432 O95835;O95835-2 O95835 O95835 >sp|O95835|LATS1_HUMAN Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 PE=1 SV=1;>sp|O95835-2|LATS1_HUMAN Isoform 2 of Serine/threonine-protein kinase LATS1 OS=Homo sapiens GN=LATS1 0.999997 54.8096 0.999974 45.8398 0.00167733 91.281 0.999997 54.8096 0.00110758 78.4 0.999967 44.8244 0.00226075 98.028 0.997185 25.4937 0.285983 25.494 0.95752 13.5297 0.582338 13.53 0.695278 3.58255 0.878998 3.5825 1 T PQVRSVTPPPPPR 14-3-3 binding;CAMK2;Proline-directed 0.0001701 0.00226075 98.028 _SVpTPPPPPR_ SVT(1)PPPPPR S(-54.81)VT(54.81)PPPPPR 3 2 514.25225 0.10064 1792500 292380 149600 0 1325100 7060.3 13987 4357.9 2874 272 187 187 957;4429;4991 1078;5039;5674 9044 5523 Mix4_TiO2_1_3 4189 9045 5525 Mix4_TiO2_1_3 4398 O96013 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1 0.999999 59.6493 0.999999 59.6493 5.38124E-25 171.38 0.870141 8.98531 5.20088E-07 107.89 0 0 0.999939 42.3628 1.51747E-24 163.05 0.00895138 -20.4286 8.30451E-05 96.366 0.999964 44.5694 8.93481E-07 100.55 0.48891 0.945795 0.00038479 87.321 1 T SGPDVGTPQPAGL ERK/MAPK;Proline-directed 0.0034 5.38124E-25 171.38 _DKRPLSGPDVGpTPQPAGLASGAK_ DKRPLSGPDVGT(1)PQPAGLASGAK DKRPLS(-59.65)GPDVGT(59.65)PQPAGLAS(-86.08)GAK 12 3 767.05292 -0.036296 24996000 20.236 3639000 47004 0 20415000 0 895060 0 2875 272 277 277 2106;2107;2108 2385;2386;2387;2388 19288 11709 Mix4_InSol_Tio2_Reinj_1 7081 19295 11720 Mix4_TiO2_Reinj_1_3 6656 O96013;O96013-4;O96013-3 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 0.861024 10.931 0.0395468 -13.6518 7.75803E-05 97.928 0 0 0.0903649 -10.0287 2.59172E-07 113.28 0.438652 0 0.604419 61.004 0.861024 10.931 1.75633 45.359 1 T LAPPACTPAAPAV FHA KAPP;Proline-directed 0.05 2.59172E-07 113.28 _GAPSPGVLGPHASEPQLAPPACpTPAAPAVPGPPGPR_ GAPS(0.069)PGVLGPHAS(0.069)EPQLAPPACT(0.861)PAAPAVPGPPGPR GAPS(-10.93)PGVLGPHAS(-10.93)EPQLAPPACT(10.93)PAAPAVPGPPGPR 23 4 864.6787 -0.20766 565150 0 0 0 0 0 0 565150 2876 272 478 478 4929;5484 5604;5605;6240;6241 47382 28955 Mix4_TiO2_Reinj_1_5 7832 53480 32677 Mix4_TiO2_Reinj_1_4 8225 O96013;O96013-4;O96013-3;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 0.803014 6.12029 0.767775 6.00782 3.50303E-16 169.97 0.573784 2.66771 0.131136 45.489 0.803014 6.12029 1.27668E-25 196.46 0.796996 7.46303 1.02856 15.413 0.490789 0 1.73432E-12 147.79 0.416617 -1.45618 3.51023E-13 154.86 1 T RKSLVGTPYWMAP ERK/MAPK;NEK6;Proline-directed 0.0034 1.27668E-25 196.46 _RKSLVGpTPYWMAPELISR_ RKS(0.196)LVGT(0.803)PY(0.001)WMAPELISR RKS(-6.12)LVGT(6.12)PY(-30.08)WMAPELIS(-106.95)R 7 3 728.70603 -0.0012803 885920 201300 49499 0 617270 17863 0 0 2877 276 871 871 2423 2746 22713 14183 Mix4_TiO2_Reinj_1_5 4380 22711 14181 Mix4_TiO2_1_5 3660 P00519-2;P00519 P00519-2 P00519-2 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4 0.966769 17.6481 0.93157 11.4449 3.23791E-06 109.01 0.765198 8.14102 0.00108295 85.704 0.966769 17.6481 0.000960756 87.17 0 0 0 0 1 T AAAEPVTPTSKAG ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 3.23791E-06 109.01 _GSALGTPAAAEPVpTPTSK_ GSALGTPAAAEPVT(0.967)PT(0.017)S(0.017)K GS(-87.17)ALGT(-70.14)PAAAEPVT(17.65)PT(-17.65)S(-17.65)K 14 2 867.91912 0.089194 915970 225520 47578 0 642870 0 0 0 2878 277 1029 1029 337 380;381;382 3096 1879 Mix4_TiO2_1_1 7546 3110 1885 Mix4_TiO2_Reinj_1_1 7912 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.373544 0 0.373544 0 0.049787 65.733 0 0 0.0885231 -6.07752 1.2087E-07 102.73 0 0 1 T FFSSPSTSRTPLL CK1 0.081 1.2087E-07 102.73 _ALMDEEDM(ox)DDVVDADEYLIPQQGFFSSPSpTSR_ ALMDEEDMDDVVDADEYLIPQQGFFS(0.084)S(0.084)PS(0.084)T(0.374)S(0.374)R ALMDEEDMDDVVDADEY(-30.68)LIPQQGFFS(-6.49)S(-6.49)PS(-6.49)T(0)S(0)R 30 3 1235.1828 0.26532 0 0 0 0 0 0 0 0 0 2879 277 693 693 1690 1897 15446 9327 Mix4_TiO2_Reinj_1_3 7046 15447 9329 Mix4_TiO2_Reinj_1_5 6957 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.994504 22.5759 0.977658 16.4107 3.67315E-26 186.13 0.979312 16.7519 2.40031E-21 166.94 0.994504 22.5759 2.09772E-31 196.16 0.864835 8.06068 0.000101 97.175 0.896569 9.37935 1.41058E-15 143.44 0.980787 17.0798 0.000581321 88.97 1 T ELVEPLTPSGEAP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 2.09772E-31 196.16 _ELVEPLpTPSGEAPNQALLR_ ELVEPLT(0.995)PS(0.005)GEAPNQALLR ELVEPLT(22.58)PS(-22.58)GEAPNQALLR 7 3 705.35583 0.042933 28596000 4556100 2692300 0 20883000 32180 261400 171360 2880 277 1041 1041 6144 7015 60888 36895 Mix4_InSol_TiO2_1 7574 60889 36896 Mix4_TiO2_1_5 6215 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.429727 0 0.0108892 -19.5313 3.29289E-17 153.82 0.0111227 -19.1298 1.32913E-16 145.16 0.429727 0 0.0152473 62.294 0 0 1 T LSSLSATSNNSTV NEK6 0.076 3.29289E-17 153.82 _TPLLSSLSApTSNNSTVACIDR_ TPLLSSLSAT(0.43)S(0.43)NNS(0.115)T(0.026)VACIDR T(-60.01)PLLS(-55.99)S(-49.49)LS(-38.6)AT(0)S(0)NNS(-5.73)T(-12.23)VACIDR 10 2 1144.0354 -0.50425 0 0 0 0 0 0 0 0 2881 277 1074 1074 6806 7787 69053 42339 Mix4_TiO2_2_2 7878 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.169211 0 0.160567 0 6.55873E-08 108.39 0.169211 0 1.5362 30.095 0.0545732 -7.61465 1.58055E-36 176.58 1 T RYSSDPTGALTED CK1;FHA2 Rad53p 0.081 1.58055E-36 176.58 _pYSSDPTGALTEDSIDDTFLPVPEYINQSVPK_ Y(0.169)S(0.169)S(0.169)DPT(0.169)GALT(0.149)EDS(0.14)IDDT(0.034)FLPVPEYINQSVPK Y(0)S(0)S(0)DPT(0)GALT(-0.55)EDS(-0.82)IDDT(-7.03)FLPVPEY(-28.35)INQS(-28.35)VPK 6 3 1160.199 0.04407 0 0 0 0 0 0 0 0 0 2882 277 1078 1078 6806 7787 69055 42341 Mix4_TiO2_Reinj_1_1 8433 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.4513 0 0.327232 0 6.55873E-08 108.39 0.149066 -0.550492 1.5362 30.095 0.4513 0 1.58055E-36 176.58 1 T DPTGALTEDSIDD FHA KAPP 0.155 1.58055E-36 176.58 _YSSDPTGALpTEDSIDDTFLPVPEYINQSVPK_ YSSDPTGALT(0.451)EDS(0.451)IDDT(0.097)FLPVPEYINQSVPK Y(-59.61)S(-59.61)S(-59.61)DPT(-47.64)GALT(0)EDS(0)IDDT(-6.66)FLPVPEY(-100.64)INQS(-105.5)VPK 10 3 1160.199 0.60566 0 0 0 0 0 0 0 0 0 2883 277 1085 1085 6806 7787 69052 42338 Mix4_TiO2_1_6 6757 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.327232 0 0.327232 0 6.55873E-08 108.39 0.0555119 -9.92308 1.5362 30.095 0.0973899 -6.65952 1.58055E-36 176.58 1 T EDSIDDTFLPVPE PLK1 0.033462 1.58055E-36 176.58 _YSSDPTGALpTEDSIDDTFLPVPEYINQSVPK_ Y(0.005)S(0.005)S(0.005)DPT(0.005)GALT(0.327)EDS(0.327)IDDT(0.327)FLPVPEYINQSVPK Y(-18.56)S(-18.56)S(-18.56)DPT(-18.56)GALT(0)EDS(0)IDDT(0)FLPVPEY(-38.17)INQS(-45.35)VPK 17 3 1160.199 -0.092488 0 0 0 0 0 0 0 0 0 2884 288 31 31 753 859 7287 4310 Mix4_TiO2_Reinj_1_3 7905 7287 4310 Mix4_TiO2_Reinj_1_3 7905 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.590675 1.63598 0.424775 -1.31621 2.55584E-11 128.75 0.590675 1.63598 1.38069E-32 183.36 1 T SSCISPTIVQQFG 1.38069E-32 183.36 _DAVFDGSSCISPpTIVQQFGYQR_ DAVFDGSS(0.004)CIS(0.405)PT(0.591)IVQQFGYQR DAVFDGS(-41.15)S(-21.69)CIS(-1.64)PT(1.64)IVQQFGY(-153.67)QR 13 3 852.38059 0.31003 911550 0 0 0 911550 0 0 0 2885 288 323 323 5350 6091 51967 31818 Mix4_TiO2_Reinj_1_3 5822 51966 31817 Mix4_TiO2_1_3 5234 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.498366 0 2.22692E-09 -86.4331 2.4306E-35 184.15 0.498366 0 2.00825E-07 102.77 0 0 0.00577119 -22.3547 0.00539154 75.957 1 T PNNLSPTGWSQPK FHA KAPP;NEK6 0.076 2.4306E-35 184.15 _SHSESASPSALSSSPNNLpSPTGWSQPK_ SHSESASPSALSSSPNNLS(0.498)PT(0.498)GWS(0.003)QPK S(-96.85)HS(-102.09)ES(-102.32)AS(-90.1)PS(-79.08)ALS(-65.73)S(-51.74)S(-44.42)PNNLS(0)PT(0)GWS(-21.86)QPK 21 3 940.75393 0.5855 0 0 0 0 0 0 0 0 2886 288 258 258 5805 6616;6617 57222 34875 Mix4_InSol_Tio2_Reinj_1 6330 57219 34872 Mix4_InSol_TiO2_1 6354 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.320627 0 0.11175 -8.2872 0.0198481 60.893 0 0 0.082107 -8.9314 0.109975 49.254 0.280279 0 0.013915 66.781 0.320627 0 0.471473 33.337 1 T SQRQRSTSTPNVH PKA 0.042 0.013915 66.781 _SpTSTPNVHMVSTTLPVDSR_ S(0.277)T(0.321)S(0.321)T(0.081)PNVHMVSTTLPVDSR S(-0.63)T(0)S(0)T(-5.98)PNVHMVS(-33.34)T(-33.34)T(-33.34)LPVDS(-33.34)R 2 3 703.66092 -0.48676 0 0 0 0 0 0 0 0 2887 288 260 260 5805 6616;6617 57208 34868 Mix4_InSol_Tio2_Reinj_1 5491 57219 34872 Mix4_InSol_TiO2_1 6354 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.449575 0 0.0229828 -15.1556 0.0198481 60.893 0 0 0.206759 -4.92055 0.109975 49.254 0.24351 0 0.013915 66.781 0.449575 0 0.471473 33.337 1 T RQRSTSTPNVHMV CK1;Polo box;Proline-directed 0.00405 0.013915 66.781 _STpSTPNVHM(ox)VSTTLPVDSR_ S(0.014)T(0.077)S(0.45)T(0.45)PNVHMVS(0.002)T(0.002)T(0.002)LPVDS(0.002)R S(-14.92)T(-7.64)S(0)T(0)PNVHMVS(-23.05)T(-23.05)T(-23.05)LPVDS(-23.05)R 4 3 708.99256 -0.54556 0 0 0 0 0 0 0 0 2888 288 234 234 6808 7791 69078 42355 Mix4_TiO2_1_3 5738 69079 42356 Mix4_TiO2_Reinj_1_3 6441 P04049-2;P04049 P04049-2 P04049-2 >sp|P04049-2|RAF1_HUMAN Isoform 1A of RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1;>sp|P04049|RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1 0.395082 0 0.395082 0 0.0121851 66.968 0.146315 -7.32061 0.00907476 70.357 1 T SQHRYSTPHAFTF CAMK2;FHA KAPP;Polo box;Proline-directed 0.00405 0.00907476 70.357 _YpSTPHAFTFNTSSPSSEGSLSQR_ Y(0.174)S(0.395)T(0.395)PHAFT(0.032)FNT(0.004)SSPSSEGSLSQR Y(-3.56)S(0)T(0)PHAFT(-10.95)FNT(-20.19)S(-34.72)S(-49.82)PS(-66.97)S(-66.97)EGS(-66.97)LS(-66.97)QR 3 3 856.70614 -0.30028 0 0 0 0 0 0 0 0 2889 306 674 674 3791 4283 35982 22271 Mix4_TiO2_Reinj_1_3 8758 35982 22271 Mix4_TiO2_Reinj_1_3 8758 P05129 P05129 P05129 >sp|P05129|KPCG_HUMAN Protein kinase C gamma type OS=Homo sapiens GN=PRKCG PE=1 SV=3 0.499999 0 0.499999 0 6.59917E-08 113.06 1 T ADFQGFTYVNPDF PDK1 0.0001168 6.59917E-08 113.06 _LVLASIDQADFQGFpTYVNPDFVHPDAR_ LVLASIDQADFQGFT(0.5)Y(0.5)VNPDFVHPDAR LVLAS(-55.29)IDQADFQGFT(0)Y(0)VNPDFVHPDAR 15 3 1039.1569 -0.7416 503130 0 0 0 503130 0 0 0 2890 306 514 514 5983 6823 59058 35845 Mix4_TiO2_1_3 7751 59057 35840 Mix4_TiO2_1_3 7428 P05129 P05129 P05129 >sp|P05129|KPCG_HUMAN Protein kinase C gamma type OS=Homo sapiens GN=PRKCG PE=1 SV=3 0.999999 62.6629 0.999999 62.6629 5.88068E-39 207.01 0.978956 16.6814 5.9736E-07 106.31 0.999997 55.5469 1.92078E-32 185.98 0.99646 24.4949 5.97298E-11 122.75 0.996676 24.7693 2.08644E-11 132.28 0.998147 27.3143 1.43858E-16 144.21 1 T PGTTTRTFCGTPD 5.88068E-39 207.01 _pTFCGTPDYIAPEIIAYQPYGK_ T(1)FCGTPDYIAPEIIAYQPYGK T(62.66)FCGT(-62.66)PDY(-132.86)IAPEIIAY(-182.66)QPY(-182.66)GK 1 3 828.71128 1.148 108510000 25971000 119760 0 80573000 87084 1428300 330920 2891 306 518 518 5983 6823 59069 35884 Mix4_TiO2_1_5 8118 59057 35840 Mix4_TiO2_1_3 7428 P05129 P05129 P05129 >sp|P05129|KPCG_HUMAN Protein kinase C gamma type OS=Homo sapiens GN=PRKCG PE=1 SV=3 0.932308 13.1658 0.932308 13.1658 5.88068E-39 207.01 0.902345 9.65677 5.9736E-07 106.31 0.839863 7.20233 1.92078E-32 185.98 0.0373754 -14.0908 5.97298E-11 122.75 0.157139 -7.29469 2.08644E-11 132.28 0.626953 2.25473 1.43858E-16 144.21 1 T TRTFCGTPDYIAP Proline-directed 0.05 5.88068E-39 207.01 _TFCGpTPDYIAPEIIAYQPYGK_ T(0.045)FCGT(0.932)PDY(0.015)IAPEIIAY(0.004)QPY(0.004)GK T(-13.17)FCGT(13.17)PDY(-17.97)IAPEIIAY(-23.76)QPY(-23.76)GK 5 2 1242.5633 0.36162 1288100 13857 58017 0 133770 0 0 1082500 2892 315;332;373 421;427;426 426 3482;3483 3930;3932 32867 20371 Mix4_InSol_Tio2_Reinj_1 3475 32829 20335 Mix4_TiO2_1_3 2679 P06241;P06241-2;P06241-3;P07947;P12931-2;P12931;P06239-3;P06239 P06241;P07947;P12931-2 P12931-2 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN PE=1 SV=3;>sp|P06241-2|FYN_HUMAN Isoform T of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN;>sp|P06241-3|FYN_HUMAN Isoform 3 of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN; 0.982174 17.4114 0.0587718 -12.0453 2.84663E-08 174.34 0.00080465 -30.9404 0.00179318 131.65 0.000843472 -30.7356 1.29324E-07 168.7 0.0331598 -14.6474 0.00282919 73.131 0.827188 6.80029 0.000135147 148.93 0.982174 17.4114 2.70637E-07 160.79 1 T IEDNEYTARQGAK 2.84663E-08 174.34 _LIEDNEYpTARQGAK_ LIEDNEY(0.018)T(0.982)ARQGAK LIEDNEY(-17.41)T(17.41)ARQGAK 8 2 844.38799 0.51507 4618600 7.9388 0 0 0 0 0 4319500 299050 2893 316 373 373 3215;5507 3647;6270 53735 32851 Mix4_TiO2_Reinj_1_5 5804 53735 32851 Mix4_TiO2_Reinj_1_5 5804 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.999999 61.9003 0.999999 59.2698 0.0313276 59.27 0 0 0.999999 61.9003 0.0226086 61.9 0.993711 21.9871 0.802251 21.987 0.997394 25.8291 0.672324 25.829 1 T NVIPPHTPVRTVM CDK1;CDK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0226086 61.9 _SNLDEEVNVIPPHpTPVR_ SNLDEEVNVIPPHT(1)PVR S(-61.9)NLDEEVNVIPPHT(61.9)PVR 14 3 665.98937 -0.0089939 1217300 57213 0 0 666350 0 242660 251130 2894 316 353 353 6079 6934 60043 36399 Mix4_TiO2_2_2 4748 60044 36400 Mix4_TiO2_Reinj_1_1 5170 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.853088 9.20002 0.60516 3.4827 0.114801 47.104 0.853088 9.20002 0.540668 28.574 0.416243 -1.4219 0.00539632 76.651 0 0 0 0 1 T SIDSFETQRTPRK CK1 0.081 0.00539632 76.651 _TLQTDSIDSFEpTQRTPR_ T(0.001)LQT(0.001)DS(0.001)IDS(0.041)FET(0.853)QRT(0.103)PR T(-28.57)LQT(-28.57)DS(-28.57)IDS(-13.2)FET(9.2)QRT(-9.2)PR 12 2 1037.9757 0.14598 117500 91230 26273 0 0 0 0 0 2895 316 356 356 6079 6934 60047 36403 Mix4_TiO2_Reinj_1_5 5731 60044 36400 Mix4_TiO2_Reinj_1_1 5170 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.988543 21.0637 0.983247 19.195 0.114801 47.104 0.153061 -6.61307 0.540668 28.574 0.988543 21.0637 0.00539632 76.651 0 0 0 0 1 T SFETQRTPRKSNL CDK1;CDK2;Proline-directed 0.0057 0.00539632 76.651 _TLQTDSIDSFETQRpTPR_ TLQTDSIDS(0.004)FET(0.008)QRT(0.989)PR T(-65.95)LQT(-65.95)DS(-58)IDS(-24.25)FET(-21.06)QRT(21.06)PR 15 2 1037.9757 -1.7709 1268800 72505 0 0 1196300 0 0 0 2896 316 778 778 6111 6975 60389 36533 Mix4_TiO2_Reinj_1_5 7610 60389 36533 Mix4_TiO2_Reinj_1_5 7610 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.886738 8.9373 0 0 0.886738 8.9373 4.8075E-07 108.66 1 T ASTRPPTLSPIPH CAMK2 0.042 4.8075E-07 108.66 _TNILQYASTRPPpTLSPIPHIPR_ TNILQYASTRPPT(0.887)LS(0.113)PIPHIPR T(-108.66)NILQY(-64.63)AS(-56.39)T(-56.39)RPPT(8.94)LS(-8.94)PIPHIPR 13 3 851.45101 0.05388 211770 0 0 0 211770 0 0 0 2897 318 14 14 2745;2761;2763 3128;3129;3146;3147;3150;3151 26211 16318 Mix4_TiO2_2_5 2800 26005 16095 Mix4_InSol_Tio2_Reinj_1 5448 P06493;P06493-2 P06493 P06493 >sp|P06493|CDK1_HUMAN Cell division protein kinase 1 OS=Homo sapiens GN=CDK1 PE=1 SV=2;>sp|P06493-2|CDK1_HUMAN Isoform CDC2deltaT of Cell division protein kinase 1 OS=Homo sapiens GN=CDK1 1 76.773 1 85.0274 6.62147E-05 151.29 1 76.773 0.000213567 139.31 0 0 1 70.1102 0.00306769 119.88 0.99929 31.5887 0.00305769 79.498 1 80.0538 0.000167389 143.06 1 94.6352 2.81479E-09 152.15 1 T EKIGEGTYGVVYK PLK1 0.033462 2.81479E-09 152.15 _IGEGpTYGVVYK_ IGEGT(1)YGVVYK IGEGT(76.77)Y(-76.77)GVVY(-107.07)K 5 2 633.29431 -0.0018185 41264000 47.971 14817000 1286400 0 17831000 42352 4078700 3208600 2898 329 888 888 1936;5998 2188;2189;6838 17744 10610 Mix4_TiO2_Reinj_1_5 5404 17737 10598 Mix4_TiO2_1_5 4611 P07814 P07814 P07814 >sp|P07814|SYEP_HUMAN Bifunctional aminoacyl-tRNA synthetase OS=Homo sapiens GN=EPRS PE=1 SV=5 0.567025 5.84333 0.19216 -5.97261 1.4944E-15 142.65 0.0980059 -9.12243 0.000576248 89.057 0.567025 5.84333 2.51174E-06 106.95 0.10117 -6.40783 0.170467 41.814 0.129149 -5.04701 0.0120601 77.85 0.133168 -6.29403 0.000331845 90.437 1 T SSDSSPTRNSEPA CK1;FHA KAPP 0.081 1.4944E-15 142.65 _EYIPGQPPLSQSSDSSPpTR_ EYIPGQPPLS(0.021)QS(0.095)S(0.022)DS(0.148)S(0.148)PT(0.567)R EY(-47.29)IPGQPPLS(-14.25)QS(-7.77)S(-14.18)DS(-5.84)S(-5.84)PT(5.84)R 18 3 709.31944 0.54947 1079900 16.214 0 0 0 1079900 0 0 0 2899 332 21 21 6785 7763 68788 42186 Mix4_TiO2_1_4 4579 68791 42190 Mix4_TiO2_Reinj_1_4 5025 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.781347 7.8816 0.781347 7.8816 4.20335E-05 97.053 0.169776 -2.31081 5.10705E-08 112.38 1.98188E-05 -46.9021 0.101148 59.961 9.7959E-05 -39.3978 0.190729 58.45 1 T KYRPENTPEPVST Proline-directed 0.05 5.10705E-08 112.38 _YRPENpTPEPVSTSVSHYGAEPTTVSPCPSSSAK_ Y(0.006)RPENT(0.781)PEPVS(0.028)T(0.028)S(0.127)VS(0.028)HYGAEPTTVSPCPSSSAK Y(-20.83)RPENT(7.88)PEPVS(-14.41)T(-14.41)S(-7.88)VS(-14.41)HY(-41.91)GAEPT(-49.63)T(-49.63)VS(-49.63)PCPS(-62.75)S(-62.75)S(-62.75)AK 6 3 1200.5381 -1.0439 842530 1.0597 842530 0 0 0 0 0 0 2900 332 27 27 6785 7763 68791 42190 Mix4_TiO2_Reinj_1_4 5025 68791 42190 Mix4_TiO2_Reinj_1_4 5025 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.289039 0 0.0282856 -14.4128 4.20335E-05 97.053 0.289039 0 5.10705E-08 112.38 4.02116E-05 -43.8294 0.101148 59.961 0.000342122 -32.5644 0.190729 58.45 1 T TPEPVSTSVSHYG FHA KAPP 0.155 5.10705E-08 112.38 _YRPENTPEPVpSTSVSHYGAEPTTVSPCPSSSAK_ Y(0.001)RPENT(0.17)PEPVS(0.289)T(0.289)S(0.22)VS(0.03)HY(0.001)GAEPTTVSPCPSSSAK Y(-23.79)RPENT(-2.31)PEPVS(0)T(0)S(-1.19)VS(-9.79)HY(-25.91)GAEPT(-77.55)T(-77.55)VS(-83.25)PCPS(-93.95)S(-98.59)S(-98.59)AK 12 3 1200.5381 -0.88168 0 0 0 0 0 0 0 0 0 2901 332 37 37 6785 7763 68783 42179 Mix4_InSol_TiO2_1 5446 68791 42190 Mix4_TiO2_Reinj_1_4 5025 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.277768 0 0.127541 -6.88501 4.20335E-05 97.053 0.116308 -8.14537 5.10705E-08 112.38 0.277768 0 0.101148 59.961 0.0648403 -9.7878 0.190729 58.45 1 T HYGAEPTTVSPCP FHA KAPP 0.155 5.10705E-08 112.38 _YRPENTPEPVSTSVSHYGAEPpTTVSPCPSSSAK_ YRPENTPEPVSTSVSHYGAEPT(0.278)T(0.278)VS(0.255)PCPS(0.023)S(0.083)S(0.083)AK Y(-48.21)RPENT(-49.62)PEPVS(-46.17)T(-44.99)S(-44.99)VS(-42.39)HY(-32.42)GAEPT(0)T(0)VS(-0.37)PCPS(-10.9)S(-5.23)S(-5.23)AK 22 3 1200.5381 -0.61152 0 0 0 0 0 0 0 0 0 2902 332 38 38 6785 7763 68783 42179 Mix4_InSol_TiO2_1 5446 68791 42190 Mix4_TiO2_Reinj_1_4 5025 P07947 P07947 P07947 >sp|P07947|YES_HUMAN Proto-oncogene tyrosine-protein kinase Yes OS=Homo sapiens GN=YES1 PE=1 SV=3 0.277768 0 0.127541 -6.88501 4.20335E-05 97.053 0.116308 -8.14537 5.10705E-08 112.38 0.277768 0 0.101148 59.961 0.0706206 -10.8189 0.190729 58.45 1 T YGAEPTTVSPCPS 5.10705E-08 112.38 _YRPENTPEPVSTSVSHYGAEPpTTVSPCPSSSAK_ YRPENTPEPVSTSVSHYGAEPT(0.278)T(0.278)VS(0.255)PCPS(0.023)S(0.083)S(0.083)AK Y(-48.21)RPENT(-49.62)PEPVS(-46.17)T(-44.99)S(-44.99)VS(-42.39)HY(-32.42)GAEPT(0)T(0)VS(-0.37)PCPS(-10.9)S(-5.23)S(-5.23)AK 23 3 1200.5381 -0.61152 0 0 0 0 0 0 0 0 0 2903 333;334 398;377 398 6434;6435 7360;7362 64994 39863 Mix4_InSol_TiO2_5 1475 65024 39903 Mix4_InSol_TiO2_1 3167 P07948;P08631;P08631-2;P07948-2 P07948;P07948-2 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3;>sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens GN=HCK PE=1 SV=5;>sp|P08631-2|HCK_HUMAN Isoform p59-HCK of Tyrosine-protein kinase HCK OS=Homo sapiens GN=HCK 0.61359 2.0083 0.0128525 -18.854 0.000319922 138.35 0.5 0 0.00521034 117.9 0.0152268 -18.1073 0.00521034 117.9 0.00710005 -21.4564 0.0194037 56.131 0.61359 2.0083 9.7793E-09 140.88 0.398414 -1.78963 1.04999E-08 139.72 1 T IEDNEYTAREGAK CK2 0.117 9.7793E-09 140.88 _VIEDNEYpTAR_ VIEDNEY(0.386)T(0.614)AR VIEDNEY(-2.01)T(2.01)AR 8 2 645.27411 -0.39013 1408800 12.907 0 6988.6 0 0 0 1401800 0 2904 360 18 18 5250;5251 5976;5977;5978;5979 51005 31255 Mix4_TiO2_1_2 2573 50976 31249 Mix4_TiO2_Reinj_1_2 3426 P10412 P10412 P10412 >sp|P10412|H14_HUMAN Histone H1.4 OS=Homo sapiens GN=HIST1H1E PE=1 SV=2 1 87.4139 1 87.4139 7.1591E-16 139.04 1 74.6788 0.00498156 74.679 1 158.901 4.19526E-22 170.46 0.998945 32.7716 0.61056 32.772 0.657396 5.84065 1.72555 5.8407 1 T PAPAEKTPVKKKA CDK1;CDK2;Proline-directed 0.0057 4.19526E-22 170.46 _(ac)SETAPAAPAAPAPAEKpTPVKK_ SETAPAAPAAPAPAEKT(1)PVKK S(-87.92)ET(-87.41)APAAPAAPAPAEKT(87.41)PVKK 17 2 1077.5458 0.15588 3513000 853870 36088 0 2442400 0 95967 84685 2905 373 74 74 3417 3859 32105 19854 Mix4_TiO2_1_6 4550 32102 19850 Mix4_TiO2_1_3 5593 P12931-2;P12931 P12931-2 P12931-2 >sp|P12931-2|SRC_HUMAN Isoform 2 of Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC;>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens GN=SRC PE=1 SV=3 0.550418 0.943336 0.550418 0.943336 1.12018E-25 198.67 0 0 0.195673 -6.13901 5.63255E-13 153.78 0.0311042 -14.9293 8.76977E-16 160.95 0.138605 -7.93307 3.31494E-16 170.3 1 T NSSDTVTSPQRAG 1.12018E-25 198.67 _LFGGFNSSDTVpTSPQR_ LFGGFNS(0.001)S(0.001)DT(0.005)VT(0.55)S(0.443)PQR LFGGFNS(-27.98)S(-27.98)DT(-20.53)VT(0.94)S(-0.94)PQR 12 2 896.89872 0.55924 13070 0.10937 13070 0 0 0 0 0 0 2906 386 401 401 1131;2134 1273;2418 19633 11987 Mix4_TiO2_Reinj_1_3 6680 19629 11976 Mix4_TiO2_1_3 5836 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.999611 34.1 0.9996 33.9793 6.15238E-26 170.81 0 0 0.999611 34.1 8.47887E-18 143.57 0.998762 31.9707 0.000163687 88.695 0.962975 14.6565 0.386027 53.076 1 T TTGLSATPPASLP FHA KAPP;NEK6;Proline-directed 0.05 6.15238E-26 170.81 _GDGGSTTGLSApTPPASLPGSLTNVK_ GDGGSTTGLSAT(1)PPASLPGSLTNVK GDGGS(-75.75)T(-73.8)T(-65.8)GLS(-34.1)AT(34.1)PPAS(-70.82)LPGS(-117.63)LT(-130.3)NVK 12 3 789.04761 -0.080482 9563000 1347600 0 0 7145500 0 538300 531550 2907 386 373 373 1177;5734 1322;6535 11053 6782 Mix4_TiO2_Reinj_1_3 8215 11052 6781 Mix4_TiO2_Reinj_1_3 8189 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.714414 8.75335 0.0459122 -8.40539 1.40186E-17 139.48 0 0 0.714414 8.75335 6.2958E-45 202.91 0 0 0.0213666 -11.8759 0.136069 53.111 0.35675 2.21105 0.0823986 56.42 1 T PNVHINTIEPVNI 6.2958E-45 202.91 _DRSSSAPNVHINpTIEPVNIDDLIR_ DRS(0.095)S(0.095)S(0.095)APNVHINT(0.714)IEPVNIDDLIR DRS(-8.75)S(-8.75)S(-8.75)APNVHINT(8.75)IEPVNIDDLIR 13 4 689.59072 -0.20501 460040 0 0 0 460040 0 0 0 2908 386 313 313 1983 2243 18046 10785 Mix4_TiO2_Reinj_1_3 7735 18051 10791 Mix4_TiO2_Reinj_1_5 7725 P15056 P15056 P15056 >sp|P15056|BRAF_HUMAN Serine/threonine-protein kinase B-raf OS=Homo sapiens GN=BRAF PE=1 SV=4 0.228762 0 0 0 0 0 0.228762 0 4.84745E-06 110.92 0 0 0 0 0 0 1 T LAETALTSGSSPS FHA KAPP 0.155 4.84745E-06 110.92 _FFEHHPIPQEEASLAETALpTSGSSPSAPASDSIGPQILTSPSPSK_ FFEHHPIPQEEAS(0.003)LAET(0.011)ALT(0.229)S(0.229)GS(0.229)S(0.229)PS(0.049)APAS(0.011)DS(0.011)IGPQILTSPSPSK FFEHHPIPQEEAS(-19.06)LAET(-13.03)ALT(0)S(0)GS(0)S(0)PS(-6.67)APAS(-13.28)DS(-13.28)IGPQILT(-43.07)S(-43.07)PS(-46.99)PS(-48.88)K 20 4 1171.5589 0.035414 0 0 0 0 0 0 0 0 2909 396 11 11 134 155 1336 837 Mix4_InSol_Tio2_Reinj_1 6127 1337 838 Mix4_TiO2_1_3 5150 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.499814 0 0.269679 -4.3264 5.12711E-32 211.94 0 0 0.320992 -3.25334 4.26462E-10 128.19 0.456017 0 1.91276E-15 145.79 0.499814 0 2.39667E-06 111.39 1 T FPGNDSTASQDVA 5.12711E-32 211.94 _(ac)ADVFPGNDpSTASQDVANR_ ADVFPGNDS(0.5)T(0.5)ASQDVANR ADVFPGNDS(0)T(0)AS(-31.29)QDVANR 10 2 993.41547 0.16525 0 0 0 0 0 0 0 0 0 2910 396 497 497 1573;5983 1767;6823 59058 35845 Mix4_TiO2_1_3 7751 59057 35840 Mix4_TiO2_1_3 7428 P17252;P05771-2;P05771 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3;>sp|P05771-2|KPCB_HUMAN Isoform PRKCB2 of Protein kinase C beta type OS=Homo sapiens GN=PRKCB;>sp|P05771|KPCB_HUMAN Protein kinase C beta type OS=Homo sapiens GN=PRKCB PE= 0.999999 62.6629 0.999999 62.6629 5.88068E-39 207.01 0.978956 16.6814 5.9736E-07 106.31 0.999997 55.5469 1.92078E-32 185.98 0.99646 24.4949 5.97298E-11 122.75 0.996676 24.7693 2.08644E-11 132.28 0.998147 27.3143 1.43858E-16 144.21 1 T DGVTTRTFCGTPD 5.88068E-39 207.01 _pTFCGTPDYIAPEIIAYQPYGK_ T(1)FCGTPDYIAPEIIAYQPYGK T(62.66)FCGT(-62.66)PDY(-132.86)IAPEIIAY(-182.66)QPY(-182.66)GK 1 3 828.71128 1.148 108510000 25971000 119760 0 80573000 87084 1428300 330920 2911 396 501 501 1573;5983 1767;6823 59069 35884 Mix4_TiO2_1_5 8118 59057 35840 Mix4_TiO2_1_3 7428 P17252;P05771-2;P05771 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3;>sp|P05771-2|KPCB_HUMAN Isoform PRKCB2 of Protein kinase C beta type OS=Homo sapiens GN=PRKCB;>sp|P05771|KPCB_HUMAN Protein kinase C beta type OS=Homo sapiens GN=PRKCB PE= 0.932308 13.1658 0.932308 13.1658 5.88068E-39 207.01 0.902345 9.65677 5.9736E-07 106.31 0.839863 7.20233 1.92078E-32 185.98 0.0373754 -14.0908 5.97298E-11 122.75 0.229572 0 2.08644E-11 132.28 0.626953 2.25473 1.43858E-16 144.21 1 T TRTFCGTPDYIAP Proline-directed 0.05 5.88068E-39 207.01 _TFCGpTPDYIAPEIIAYQPYGK_ T(0.045)FCGT(0.932)PDY(0.015)IAPEIIAY(0.004)QPY(0.004)GK T(-13.17)FCGT(13.17)PDY(-17.97)IAPEIIAY(-23.76)QPY(-23.76)GK 5 2 1242.5633 0.36162 1288100 13857 58017 0 133770 0 0 1082500 2912 396 638 638 2387 2704 22244 13864 Mix4_TiO2_Reinj_2_1 5493 22244 13864 Mix4_TiO2_Reinj_2_1 5493 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.999999 62.273 0.999907 43.2336 0.00188773 91.836 0.999999 62.273 1.73627E-06 109.54 2 T RGQPVLTPPDQLV CK2;ERK/MAPK;FHA1 Rad53p;Proline-directed 0.0034 1.73627E-06 109.54 _GQPVLpTPPDQLVIANIDQSDFEGFpSYVNPQFVHPILQSAV_ GQPVLT(1)PPDQLVIANIDQS(0.023)DFEGFS(0.489)Y(0.489)VNPQFVHPILQSAV GQPVLT(62.27)PPDQLVIANIDQS(-13.34)DFEGFS(0)Y(0)VNPQFVHPILQS(-43.13)AV 6 4 1135.7933 0.18999 5060800 0 0 0 3286900 1773900 0 0 2913 396 228 228 5790 6596 57036 34792 Mix4_TiO2_Reinj_1_3 7565 57037 34793 Mix4_TiO2_Reinj_1_4 7521 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.499999 0 0.32916 -3.08902 4.61543E-39 237.8 0.0773107 -10.0985 0.855646 10.791 0.499999 0 1.41018E-50 263.59 0.122166 -8.56462 0.022659 61.295 0.182192 -6.52121 1.73817E-29 215.97 0.0969676 -9.69012 1.31385E-15 179.33 1 T QWNESFTFKLKPS FHA2 Rad53p 0.114 1.41018E-50 263.59 _STLNPQWNEpSFTFK_ STLNPQWNES(0.5)FT(0.5)FK S(-58.18)T(-58.18)LNPQWNES(0)FT(0)FK 12 3 593.5977 -0.37866 142560 0 0 0 142560 0 0 0 2914 398;426;429 196;196;196 196 2422;6306;6307 2745;7206;7207 63079 38439 Mix4_TiO2_1_6 6933 63092 38462 Mix4_TiO2_Reinj_1_5 8933 P17612;P17612-2;P22612;P22694;P22694-2;P22694-6;P22694-7;P22694-5;P22694-3;P22694-4;P22694-8 P17612;P22612;P22694 P17612 >sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA PE=1 SV=2;>sp|P17612-2|KAPCA_HUMAN Isoform C(s) of cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA;>sp|P22612|KAPCG_HUMAN 0.987318 18.9126 0.987318 18.9126 4.35932E-26 184.42 0.846688 7.42147 1.40117E-15 143.5 0.915346 10.3585 1.6275E-31 200.28 0.984346 17.9853 4.35932E-26 184.42 0.577571 1.36348 2.47929E-10 128.68 0.499024 0 2.00406E-06 109.2 1 T KRVKGRTWTLCGT FHA2 Rad53p 0.114 1.6275E-31 200.28 _pTWTLCGTPEYLAPEIILSK_ T(0.987)WT(0.013)LCGTPEYLAPEIILSK T(18.91)WT(-18.91)LCGT(-84.26)PEY(-120.63)LAPEIILS(-147.59)K 1 2 1136.5522 0.33501 254420000 12709000 210670 0 239980000 1244100 274980 0 2915 398;426;429 198;198;198 198 2422;6306;6307 2745;7206;7207 63114 38468 Mix4_TiO2_Reinj_1_4 8870 63092 38462 Mix4_TiO2_Reinj_1_5 8933 P17612;P17612-2;P22612;P22694;P22694-2;P22694-6;P22694-7;P22694-5;P22694-3;P22694-4;P22694-8 P17612;P22612;P22694 P17612 >sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA PE=1 SV=2;>sp|P17612-2|KAPCA_HUMAN Isoform C(s) of cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA;>sp|P22612|KAPCG_HUMAN 0.98314 17.6594 0.911371 10.123 4.35932E-26 184.42 0.876205 9.28318 1.40117E-15 143.5 0.98314 17.6594 1.6275E-31 200.28 0.915327 10.3939 4.35932E-26 184.42 0.905668 9.84669 2.47929E-10 128.68 0.499024 0 2.00406E-06 109.2 1 T VKGRTWTLCGTPE CAMK2 0.042 1.6275E-31 200.28 _TWpTLCGTPEYLAPEIILSKGYNK_ T(0.017)WT(0.983)LCGTPEYLAPEIILSKGYNK T(-17.66)WT(17.66)LCGT(-59.73)PEY(-51.99)LAPEIILS(-89.89)KGY(-89.89)NK 3 3 912.11145 0.19767 174670000 9012900 177930 0 161860000 572690 3040600 0 2916 398;426;429 202;202;202 202 2422;6306;6307 2745;7206;7207 22684 14174 Mix4_InSol_Tio2_Reinj_3 4114 63092 38462 Mix4_TiO2_Reinj_1_5 8933 P17612;P17612-2;P22612;P22694;P22694-2;P22694-6;P22694-7;P22694-5;P22694-3;P22694-4;P22694-8 P17612;P22612;P22694 P17612 >sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA PE=1 SV=2;>sp|P17612-2|KAPCA_HUMAN Isoform C(s) of cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens GN=PRKACA;>sp|P22612|KAPCG_HUMAN 0.753436 6.40332 0.469019 2.4715 4.35932E-26 184.42 0.412397 1.49244 1.40117E-15 143.5 0.453241 0 1.6275E-31 200.28 0.00149153 -26.0537 4.35932E-26 184.42 0.365396 -1.55323 2.47929E-10 128.68 0.753436 6.40332 2.00406E-06 109.2 1 T TWTLCGTPEYLAP NEK6;Proline-directed 0.05 1.6275E-31 200.28 _GRTWTLCGpTPEYLAPEIILSK_ GRT(0.045)WT(0.172)LCGT(0.753)PEY(0.014)LAPEIILS(0.014)K GRT(-12.2)WT(-6.4)LCGT(6.4)PEY(-17.2)LAPEIILS(-17.2)K 9 3 829.07808 -0.12045 269850 0 0 0 0 0 0 269850 2917 409 69 69 3265;3266;6658 3700;3701;7623 67544 41476 Mix4_TiO2_Reinj_1_5 2224 30872 19169 Mix4_TiO2_Reinj_1_5 2161 P19338 P19338 P19338 >sp|P19338|NUCL_HUMAN Nucleolin OS=Homo sapiens GN=NCL PE=1 SV=3 0.997251 25.5966 0.5 0 0.235741 35.878 0.5 0 0.999134 8.6234 0.997251 25.5966 0.00104095 83.921 0.5 0 0.00638103 65.218 0.953599 13.1284 0.0291801 53.647 1 T KVVVSPTKKVAVA 0.00104095 83.921 _VVVSPpTKK_ VVVS(0.003)PT(0.997)KK VVVS(-25.6)PT(25.6)KK 6 2 469.25954 0.050444 1612800 75943 10229 0 699480 0 791830 35345 2918 420 19 19 238 273 2377 1508 Mix4_TiO2_2_3 2709 2376 1507 Mix4_TiO2_1_3 3049 P20700 P20700 P20700 >sp|P20700|LMNB1_HUMAN Lamin-B1 OS=Homo sapiens GN=LMNB1 PE=1 SV=2 0.574739 1.31302 1.30573E-07 -68.8341 0.00936512 74.379 0.574739 1.31302 0.173363 33.82 0 0 0 0 1 T SRAGGPTTPLSPT FHA2 Rad53p 0.114 0.00936512 74.379 _AGGPpTTPLSPTR_ AGGPT(0.575)T(0.425)PLSPTR AGGPT(1.31)T(-1.31)PLS(-33.82)PT(-33.82)R 5 2 617.79501 0.38134 12596 0 12596 0 0 0 0 0 2919 422 107 107 2310;3761;3762 2613;4244;4245 35549 21965 Mix4_TiO2_1_6 4092 35532 21942 Mix4_TiO2_Reinj_1_2 5324 P21796 P21796 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens GN=VDAC1 PE=1 SV=2 0.603313 3.37962 0.603313 3.37962 4.22379E-09 166.99 0 0 0.172577 -2.53944 4.21292E-09 167.02 0 0 0.0859481 -6.96923 4.13106E-05 114.67 0.450174 -0.171573 0.00168515 89.982 1 T SSFSPNTGKKNAK CK1 0.081 4.21292E-09 167.02 _LTFDSSFSPNpTGKK_ LTFDS(0.067)S(0.053)FS(0.277)PNT(0.603)GKK LT(-38.09)FDS(-9.55)S(-10.59)FS(-3.38)PNT(3.38)GKK 11 2 804.8689 0.26911 99785 0.16089 99785 0 0 0 0 0 0 2920 422 70 70 6695 7666 67914 41697 Mix4_TiO2_Reinj_1_2 6328 67914 41697 Mix4_TiO2_Reinj_1_2 6328 P21796 P21796 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens GN=VDAC1 PE=1 SV=2 0.988717 19.4273 0.988717 19.4273 0.00651326 70.998 1 T WTEYGLTFTEKWN CK2 0.117 0.00651326 70.998 _WTEYGLpTFTEK_ WTEYGLT(0.989)FT(0.011)EK WT(-71)EY(-56.79)GLT(19.43)FT(-19.43)EK 7 2 727.81561 0.37101 19848 0.49538 0 0 0 19848 0 0 0 2921 429 341 341 2435 2761 22853 14289 Mix4_TiO2_1_4 6313 22854 14291 Mix4_TiO2_1_4 6973 P22694;P22694-2;P22694-6;P22694-7;P22694-5;P22694-3;P22694-4 P22694 P22694 >sp|P22694|KAPCB_HUMAN cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens GN=PRKACB PE=1 SV=2;>sp|P22694-2|KAPCB_HUMAN Isoform Beta2 of cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens GN=PRKACB;>sp|P22694-6|KAPCB_HUMA 0.615569 2.04459 0.615569 2.04459 3.37435E-47 230.12 0 0 0.566343 1.15933 1.7007E-17 149.35 0.49657 0 0.79309 32.301 0 0 0.297224 -1.86983 1.83969 8.7186 1 T DIRVSITEKCAKE 3.37435E-47 230.12 _GSGDTSNFDDYEEEDIRVSIpTEK_ GSGDTSNFDDYEEEDIRVS(0.384)IT(0.616)EK GS(-75.97)GDT(-81.87)S(-82.4)NFDDY(-74.6)EEEDIRVS(-2.04)IT(2.04)EK 21 2 1343.5556 0.30008 1043700 309220 0 0 734510 0 0 0 2922 434 220 220 798;3154 905;3580 29947 18626 Mix4_TiO2_Reinj_1_2 5491 7626 4509 Mix4_TiO2_Reinj_1_2 4934 P23396 P23396 P23396 >sp|P23396|RS3_HUMAN 40S ribosomal protein S3 OS=Homo sapiens GN=RPS3 PE=1 SV=2 0.499943 0 0.441409 0 1.67414E-09 172.39 0.198664 -4.81246 0.0204282 60.895 0.499943 0 2.72828E-13 178.6 0 0 0.490181 0 0.000269649 83.674 0.163854 -6.65961 0.00741044 76.335 1 T KDEILPTTPISEQ FHA2 Rad53p 0.114 2.72828E-13 178.6 _KPLPDHVSIVEPKDEILPpTTPISEQK_ KPLPDHVSIVEPKDEILPT(0.5)T(0.5)PISEQK KPLPDHVS(-91.95)IVEPKDEILPT(0)T(0)PIS(-36.41)EQK 19 3 997.52105 0.34411 649820 0.83042 0 0 0 649820 0 0 0 2923 434 221 221 798;3154 905;3580 7626 4509 Mix4_TiO2_Reinj_1_2 4934 7626 4509 Mix4_TiO2_Reinj_1_2 4934 P23396 P23396 P23396 >sp|P23396|RS3_HUMAN 40S ribosomal protein S3 OS=Homo sapiens GN=RPS3 PE=1 SV=2 0.999173 31.6938 0.980859 17.1033 1.67414E-09 172.39 0.908391 10.5772 0.0204282 60.895 0.999173 31.6938 2.72828E-13 178.6 0 0 0.964588 17.2611 0.000269649 83.674 0.980111 17.5753 0.00741044 76.335 1 T DEILPTTPISEQK ERK/MAPK;FHA KAPP;NEK6;Proline-directed;WW GroupIV 0.0023175 2.72828E-13 178.6 _DEILPTpTPISEQK_ DEILPT(0.001)T(0.999)PISEQK DEILPT(-31.69)T(31.69)PIS(-38.23)EQK 7 2 775.87111 -0.38109 15815000 20.211 3879200 133930 0 11399000 0 226980 175940 2924 435 399 399 4757 5404 45367 27740 Mix4_TiO2_Reinj_1_4 9093 45367 27740 Mix4_TiO2_Reinj_1_4 9093 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 0.261184 0 0 0 0.261184 0 0.00604194 78.764 1 T DSPDDSTLSESAN CK2;PLK;PLK1 0.0027378 0.00604194 78.764 _QTPVDSPDDpSTLSESANQVFLGFTYVAPSVLESVK_ QT(0.047)PVDS(0.148)PDDS(0.261)T(0.261)LS(0.261)ES(0.021)ANQVFLGFTYVAPSVLESVK QT(-7.47)PVDS(-2.45)PDDS(0)T(0)LS(0)ES(-10.9)ANQVFLGFT(-45.76)Y(-56.31)VAPS(-70.59)VLES(-73.25)VK 11 3 1269.9345 1.4068 0 0 0 0 0 0 0 0 2925 435 444 444 6167;6168 7041;7042;7043 61121 37040 Mix4_InSol_Tio2_Reinj_1 8361 61126 37047 Mix4_TiO2_1_4 7225 P23443;P23443-2 P23443 P23443 >sp|P23443|KS6B1_HUMAN Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 PE=1 SV=2;>sp|P23443-2|KS6B1_HUMAN Isoform Alpha II of Ribosomal protein S6 kinase beta-1 OS=Homo sapiens GN=RPS6KB1 0.847782 7.4787 0.453685 -0.806052 2.64526E-12 143.15 1.09128E-06 -59.6206 0.0696267 73.937 0.129885 -7.99515 1.37148E-08 119.21 0.138778 -7.87398 0.0207192 64.156 0.847782 7.4787 0.220608 38.525 1 T FIGSPRTPVSPVK CK1;ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 2.64526E-12 143.15 _pTPVSPVKFSPGDFWGR_ T(0.848)PVS(0.152)PVKFS(0.001)PGDFWGR T(7.48)PVS(-7.48)PVKFS(-30.72)PGDFWGR 1 2 928.94019 -0.17547 626180 0 0 0 0 0 0 626180 2926 441 14 14 2761;2762;6384 3146;3147;3149;7304;7305 26211 16318 Mix4_TiO2_2_5 2800 26202 16287 Mix4_TiO2_1_6 3226 P24941;Q00526 P24941 P24941 >sp|P24941|CDK2_HUMAN Cell division protein kinase 2 OS=Homo sapiens GN=CDK2 PE=1 SV=2;>sp|Q00526|CDK3_HUMAN Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1 1 76.773 1 85.0274 6.62147E-05 151.29 1 76.773 0.000213567 139.31 0 0 1 70.1102 0.00306769 119.88 0.99929 31.5887 0.00305769 79.498 1 80.0538 0.000167389 143.06 1 94.6352 4.23009E-09 149.86 1 T EKIGEGTYGVVYK PLK1 0.033462 6.62147E-05 151.29 _IGEGpTYGVVYK_ IGEGT(1)YGVVYK IGEGT(76.77)Y(-76.77)GVVY(-107.07)K 5 2 633.29431 -0.0018185 41765000 48.553 14817000 1286400 0 17893000 42352 3895600 3831000 2927 441 158 158 6318 7218 63231 38557 Mix4_TiO2_Reinj_1_2 6995 63239 38566 Mix4_TiO2_Reinj_1_6 6696 P24941;Q00526 P24941 P24941 >sp|P24941|CDK2_HUMAN Cell division protein kinase 2 OS=Homo sapiens GN=CDK2 PE=1 SV=2;>sp|Q00526|CDK3_HUMAN Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1 0.855228 7.76658 0.494718 0 3.82434E-06 151.44 0.0756598 -10.8485 0.0421883 53.183 0.855228 7.76658 3.10519E-13 187.76 0.399001 -1.66579 0.000581395 109.48 0.333186 0 8.95467E-05 124.47 0.197152 -4.87454 0.0058844 81.798 1 T FGVPVRTYTHEVV 3.10519E-13 187.76 _pTYTHEVVTLWYR_ T(0.855)Y(0.002)T(0.143)HEVVTLWYR T(7.77)Y(-26.92)T(-7.77)HEVVT(-54.65)LWY(-54.65)R 1 2 824.38198 0.0408 378780 0 0 0 378780 0 0 0 2928 441 160 160 6318 7218 63237 38563 Mix4_TiO2_Reinj_1_4 7751 63239 38566 Mix4_TiO2_Reinj_1_6 6696 P24941;Q00526 P24941 P24941 >sp|P24941|CDK2_HUMAN Cell division protein kinase 2 OS=Homo sapiens GN=CDK2 PE=1 SV=2;>sp|Q00526|CDK3_HUMAN Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1 0.996414 24.4911 0.991137 20.4855 3.82434E-06 151.44 0.919835 10.8485 0.0421883 53.183 0.996414 24.4911 3.10519E-13 187.76 0.993165 21.8005 0.000581395 109.48 0.927994 11.1018 8.95467E-05 124.47 0.901427 12.6251 0.0058844 81.798 1 T VPVRTYTHEVVTL CAMK2 0.042 3.10519E-13 187.76 _TYpTHEVVTLWYR_ T(0.004)YT(0.996)HEVVTLWYR T(-24.49)Y(-43.59)T(24.49)HEVVT(-96.93)LWY(-116.24)R 3 3 549.92375 -0.03391 15927000 1351800 22805 0 13735000 165750 327480 323850 2929 450 198 198 2692 3065;3066 25372 15677 Mix4_InSol_TiO2_3 3370 25383 15701 Mix4_TiO2_1_4 5638 P27361 P27361 P27361 >sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 OS=Homo sapiens GN=MAPK3 PE=1 SV=4 0.918706 14.4259 0.493272 -0.341642 2.85858E-11 136.39 0.376643 -2.29962 1.08373 17.132 0.0835405 -13.4824 1.51641E-10 132.06 0.00261518 -29.3849 0.421021 34.623 0.918706 14.4259 4.66762E-10 120.96 0.0384897 -14.6895 1.74085E-06 110.37 2 T DPEHDHTGFLTEY FHA2 Rad53p 0.114 2.85858E-11 136.39 _IADPEHDHpTGFLTEpYVATR_ IADPEHDHT(0.919)GFLT(0.084)EY(0.805)VAT(0.192)R IADPEHDHT(14.43)GFLT(-13.98)EY(7.36)VAT(-7.36)R 9 2 1166.4878 0.1611 42152 0 0 0 0 0 42152 0 2930 450 202 202 2692 3065;3066 25293 15622 Mix4_InSol_Tio2_Reinj_1 7643 25308 15651 Mix4_TiO2_Reinj_1_4 5898 P27361 P27361 P27361 >sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 OS=Homo sapiens GN=MAPK3 PE=1 SV=4 0.997123 27.8982 0.994847 22.9349 1.87145E-15 139.09 0.988597 22.0781 0.00547165 75.219 0.999998 56.7263 1.51641E-10 132.06 0.993417 22.8636 0.421021 34.623 0.9969 25.0944 1.36296E-15 143.88 0.997123 27.8982 3.28325E-07 116.65 1 T DHTGFLTEYVATR 3.74699E-21 161.88 _IADPEHDHTGFLpTEYVATR_ IADPEHDHT(0.002)GFLT(0.997)EY(0.001)VATR IADPEHDHT(-27.9)GFLT(27.9)EY(-29.44)VAT(-39.04)R 13 3 751.33884 0.62344 1698600 1111200 109030 0 0 0 218480 259930 2931 450 207 207 2692 3065;3066 25392 15725 Mix4_TiO2_1_6 4564 25383 15701 Mix4_TiO2_1_4 5638 P27361 P27361 P27361 >sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 OS=Homo sapiens GN=MAPK3 PE=1 SV=4 0.506484 0 0.506484 0 2.85858E-11 136.39 0.0734908 -9.98607 0.00547165 75.219 0.0666453 -15.9388 1.51641E-10 132.06 0.0105512 -22.8636 0.421021 34.623 0.298905 -7.02141 4.66762E-10 120.96 0.235825 -3.93952 3.28325E-07 116.65 2 T LTEYVATRWYRAP 2.85858E-11 136.39 _IADPEHDHTGFLpTEpYVATR_ IADPEHDHT(0.032)GFLT(0.944)EY(0.518)VAT(0.506)R IADPEHDHT(-13.47)GFLT(12.77)EY(0)VAT(0)R 18 2 1166.4878 -0.63444 27715 27715 0 0 0 0 0 0 2932 451;452 559;543 559 1718;6163;6164 1933;7036;7037;7038 15778 9554 Mix4_TiO2_1_3 3928 61023 36985 Mix4_InSol_TiO2_1 4310 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.991375 20.7974 0.991375 20.7974 1.51654E-12 139.48 0.000145768 -38.2739 0.240656 38.274 0.978556 16.9772 5.53384E-26 197.16 0.29516 0 1.35382E-33 217.99 0.788051 8.7606 1.13971E-06 115.94 1 T TIPDQRTPVASTH FHA KAPP;Proline-directed 0.05 1.35382E-33 217.99 _ENSTIPDQRpTPVASTHSISSAATPDR_ ENS(0.008)TIPDQRT(0.991)PVASTHSISSAATPDR ENS(-20.8)T(-34.31)IPDQRT(20.8)PVAS(-52.88)T(-59.71)HS(-65.06)IS(-70.2)S(-73.67)AAT(-86.25)PDR 10 3 940.10496 -0.13415 864470 233210 0 0 607320 0 0 23950 2933 451;452 564;548 564 1718;6163;6164 1933;7036;7037;7038 61024 36986 Mix4_InSol_TiO2_2 3198 61023 36985 Mix4_InSol_TiO2_1 4310 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.74106 7.56931 0.717426 4.00461 1.36614E-20 188.95 0.000145768 -38.2739 0.240656 38.274 0.539428 0.554538 0.118179 46.637 0.74106 7.56931 1.35382E-33 217.99 0.706175 7.24211 1.13971E-06 115.94 1 T RTPVASTHSISSA FHA2 Rad53p 0.114 1.35382E-33 217.99 _TPVASpTHSISSAATPDR_ T(0.002)PVAS(0.1)T(0.741)HS(0.13)IS(0.004)S(0.024)AATPDR T(-26.5)PVAS(-8.72)T(7.57)HS(-7.57)IS(-22.2)S(-14.97)AAT(-49.72)PDR 6 2 889.40945 0.29346 122590 0 0 0 0 0 63165 59428 2934 451;452 572;556 572 1718;6163;6164 1933;7036;7037;7038 61039 37001 Mix4_TiO2_Reinj_1_3 3506 61023 36985 Mix4_InSol_TiO2_1 4310 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.999978 47.3638 0.999968 44.9244 1.51654E-12 139.48 0.979612 17.4991 0.240656 38.274 0.999978 47.3638 5.53384E-26 197.16 0.0212364 -11.4298 1.35382E-33 217.99 0.0112226 -16.9007 1.13971E-06 115.94 1 T SISSAATPDRIRF CDK1;CDK2;CK1;Proline-directed 0.0057 1.35382E-33 217.99 _TPVASTHSISSAApTPDR_ TPVASTHSISSAAT(1)PDR T(-123.53)PVAS(-89.04)T(-77.8)HS(-63.08)IS(-54.62)S(-47.36)AAT(47.36)PDR 14 2 889.40945 -0.22498 1186900 254890 12657 0 919360 0 0 0 2935 451;452;1430;1713 234;234;214;215 3362 3803 31685 19605 Mix4_TiO2_Reinj_1_3 7911 31677 19590 Mix4_TiO2_1_3 7130 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6;Q96L34;Q96L34-2;Q9P0L2;Q9P0L2-3;Q9P0L2-2 P27448;P27448-7;Q96L34;Q9P0L2 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 1 79.6197 1 89.4678 5.47474E-32 209.73 0.999862 38.6311 0.000479152 90.715 1 79.6197 7.64911E-26 176.24 1 65.2413 1.35075E-10 132.64 0.999992 50.7817 0.00016147 96.142 1 T LGSKLDTFCGSPP;VGGKLDTFCGSPP;VGNKLDTFCGSPP 5.47474E-32 209.73 _LDpTFCGSPPYAAPELFQGK_ LDT(1)FCGSPPYAAPELFQGK LDT(79.62)FCGS(-79.62)PPY(-134.48)AAPELFQGK 3 2 1089.4843 0.34998 25188000 9017200 41928 0 15933000 0 104650 91517 2936 451;452 530;514 530 4971 5653 47976 29331 Mix4_TiO2_Reinj_1_3 2627 47976 29331 Mix4_TiO2_Reinj_1_3 2627 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.99997 45.8222 0 0 0.99997 45.8222 0.0266184 54.458 1 T GMTRRNTYVCSER CAMK2;CHK1;PKA 0.004788 0.0266184 54.458 _RNpTYVCSER_ RNT(1)YVCSER RNT(45.82)Y(-45.82)VCS(-54.46)ER 3 2 632.76064 0.58106 237140 0 0 0 237140 0 0 0 2937 451;452 614;598 614 5051;5913 5745;6744;6745 58298 35385 Mix4_TiO2_1_3 4841 58298 35385 Mix4_TiO2_1_3 4841 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.448473 0.647922 0.448473 0.647922 0.0190009 61.352 0.0549711 -9.33311 0.361316 44.07 0.000983709 -29.1036 0.0204244 61.926 2 T SLSHEATPLSQTR FHA KAPP;Proline-directed 0.05 0.0190009 61.352 _TATYNGPPApSPSLSHEApTPLSQTR_ TATYNGPPAS(0.849)PS(0.179)LS(0.389)HEAT(0.448)PLS(0.068)QT(0.068)R T(-60.04)AT(-55.1)Y(-61.35)NGPPAS(7.73)PS(-7.73)LS(-0.65)HEAT(0.65)PLS(-8.35)QT(-8.35)R 18 3 881.72111 -1.9452 0 0 0 0 0 0 0 0 2938 463 181 181 6326 7230;7231 63417 38683 Mix4_InSol_Tio2_Reinj_1 6985 63430 38730 Mix4_TiO2_1_4 6576 P28482 P28482 P28482 >sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 OS=Homo sapiens GN=MAPK1 PE=1 SV=3 0.934377 13.395 0.542468 0.77833 4.35248E-21 159.6 0.833403 10.2044 4.27442E-06 99.111 0.0608513 -14.0598 3.53769E-16 153.35 0.197016 -6.12574 0.0070664 73.606 0.500126 0 0.000120668 96.839 0.934377 13.395 1.35328E-10 132.61 1 T DPDHDHTGFLTEY FHA2 Rad53p 0.114 9.74781E-27 192.82 _VADPDHDHpTGFLTEYVATR_ VADPDHDHT(0.934)GFLT(0.011)EY(0.043)VAT(0.011)R VADPDHDHT(13.4)GFLT(-19.12)EY(-13.4)VAT(-19.12)R 9 3 741.99507 0.099961 140550 0.083299 0 13325 0 0 0 0 127230 2939 463 185 185 6326 7230;7231 63419 38686 Mix4_InSol_Tio2_Reinj_1 7512 63430 38730 Mix4_TiO2_1_4 6576 P28482 P28482 P28482 >sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 OS=Homo sapiens GN=MAPK1 PE=1 SV=3 0.999991 50.6742 0.998852 29.9877 9.74781E-27 192.82 0.999765 37.2908 4.27442E-06 99.111 0.992109 21.2072 2.34113E-21 167.16 0.999046 30.4192 0.0070664 73.606 0.998827 29.6223 2.26358E-10 129.44 0.999991 50.6742 1.35328E-10 132.61 1 T DHTGFLTEYVATR 9.74781E-27 192.82 _VADPDHDHTGFLpTEYVATR_ VADPDHDHTGFLT(1)EYVATR VADPDHDHT(-50.67)GFLT(50.67)EY(-66.61)VAT(-63.09)R 13 2 1112.489 -0.12195 80565000 47.747 943200 1156600 0 78060000 0 255520 149430 2940 463 190 190 6326 7230;7231 63624 39039 Mix4_TiO2_2_1 3630 63604 38956 Mix4_TiO2_1_4 5334 P28482 P28482 P28482 >sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 OS=Homo sapiens GN=MAPK1 PE=1 SV=3 0.816725 6.64149 0.7773 5.25979 4.35248E-21 159.6 0.816725 6.64149 1.69662E-05 98.609 0.112928 -10.4881 3.53769E-16 153.35 0.140462 -8.58485 0.0070664 73.606 0.23 -5.23655 2.26358E-10 129.44 0.478301 1.43675 1.35328E-10 132.61 2 T LTEYVATRWYRAP 4.35248E-21 159.6 _VADPDHDHTGFLpTEYVApTR_ VADPDHDHT(0.097)GFLT(0.872)EY(0.214)VAT(0.817)R VADPDHDHT(-10.18)GFLT(10.18)EY(-6.64)VAT(6.64)R 18 2 1152.4721 -0.020512 94004 0.055712 55470 38534 0 0 0 0 0 2941 465 883 883 391;6054 447;6905 3727 2221 Mix4_TiO2_1_5 6094 3726 2220 Mix4_TiO2_1_5 6085 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.572981 1.27693 0.572981 1.27693 5.3219E-05 113.64 0.0103008 -19.8263 0.0761753 43.537 0.466963 -0.574745 0.000945291 102.6 0.180351 -6.57508 0.997394 6.5751 0 0 1 T APDSLKTLADFDP CK1;CK2;FHA1 Rad53p 0.059 5.3219E-05 113.64 _APDSLKpTLADFDPR_ APDS(0.427)LKT(0.573)LADFDPR APDS(-1.28)LKT(1.28)LADFDPR 7 3 542.59054 -1.2196 13861 13861 0 0 0 0 0 0 2942 465 647 647 1918 2169 17604 10541 Mix4_TiO2_Reinj_1_5 5090 17603 10540 Mix4_TiO2_1_5 4305 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 1 46.2735 1 77.862 0.00129484 77.862 0 0 1 46.2735 0.0491771 46.273 0 0 0 0 1 T VPVAIKTLKAGYT FHA KAPP 0.155 0.00129484 77.862 _EVPVAIKpTLK_ EVPVAIKT(1)LK EVPVAIKT(46.27)LK 8 2 589.33324 0.19313 712370 184730 0 0 527630 0 0 0 2943 465 151 151 2728 3109 25774 15929 Mix4_TiO2_Reinj_1_6 6060 25773 15927 Mix4_TiO2_Reinj_1_5 7077 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.514535 0.931459 0.00803988 -18.8523 0.000283464 95.453 0.514535 0.931459 8.94037E-26 182.6 0.0382809 -13.7793 0.081056 52.358 0 0 0 0 1 T IAPDEITVSSDFE FHA KAPP;PLK1 0.033462 8.94037E-26 182.6 _IDTIAPDEIpTVSSDFEAR_ IDTIAPDEIT(0.515)VS(0.415)S(0.07)DFEAR IDT(-72.43)IAPDEIT(0.93)VS(-0.93)S(-8.65)DFEAR 10 2 1029.967 -0.079685 33769 0.050711 0 0 0 33769 0 0 0 2944 465 898 898 3637;6600 4099;4100;4101;7553;7554;7555 34186 21092 Mix4_InSol_Tio2_Reinj_2 4399 34205 21165 Mix4_TiO2_Reinj_1_1 5141 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.82863 9.84434 0.800054 9.54735 6.56777E-08 156.45 0.433303 -1.04292 0.0775713 44.853 0.649813 0.749362 0.00133544 95.416 0.177729 -10.748 0.148176 37.446 0.571702 1.93318 4.9386E-05 118.83 0.82863 9.84434 3.95509E-05 122.99 1 T SIRLPSTSGSEGV FHA KAPP;NEK6 0.076 8.1107E-09 158.77 _LPSpTSGSEGVPFR_ LPS(0.086)T(0.829)S(0.049)GS(0.037)EGVPFR LPS(-9.84)T(9.84)S(-12.32)GS(-13.51)EGVPFR 4 2 707.32413 -0.12701 880590 8.9835 23357 0 0 0 0 344450 512780 2945 465 587 587 6319 7219;7220 63321 38606 Mix4_TiO2_1_5 4105 63321 38606 Mix4_TiO2_1_5 4105 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.503797 0 0.503797 0 1.4034E-12 140.78 7.37447E-05 -40.3465 0.176563 40.346 0.499998 0 4.76407E-06 109.09 0 0 0.0441039 -10.1439 8.58534E-06 101.85 0.0252257 -15.0488 2.80274E-09 129.75 2 T QLKPLKTYVDPHT CK2;FHA1 Rad53p 0.059 1.4034E-12 140.78 _pTYVDPHTpYEDPNQAVLK_ T(0.504)Y(0.496)VDPHT(0.1)Y(0.9)EDPNQAVLK T(0)Y(0)VDPHT(-9.22)Y(9.22)EDPNQAVLK 1 2 1075.4476 1.1581 1032600 0.78299 0 0 0 1032600 0 0 0 2946 465 593 593 6319 7219;7220 63284 38589 Mix4_InSol_Tio2_Reinj_2 3875 63288 38593 Mix4_TiO2_1_5 4286 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.903012 9.73171 0.5 0 1.20158E-12 143.04 0.499933 0 0.176563 40.346 0.842017 7.26719 4.76407E-06 109.09 0 0 0.723153 4.24336 8.58534E-06 101.85 0.903012 9.73171 2.80274E-09 129.75 1 T TYVDPHTYEDPNQ CK2;FHA1 Rad53p 0.059 1.20158E-12 143.04 _TYVDPHpTYEDPNQAVLK_ TYVDPHT(0.903)Y(0.096)EDPNQAVLK T(-32.87)Y(-32.87)VDPHT(9.73)Y(-9.73)EDPNQAVLK 7 2 1035.4644 0.07618 7915100 6.002 933580 60869 0 5937000 0 340680 643010 2947 465 773 773 6467;6468 7397;7399 65391 40091 Mix4_InSol_TiO2_2 4320 65319 40056 Mix4_TiO2_1_4 3218 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.514326 3.51533 0.157706 -7.26415 2.4347E-54 269.2 0.115621 -8.82966 1.08721E-15 157.36 0.0181496 -17.3314 1.75089E-20 191.59 0.173626 -6.67521 0.0147885 69.135 0.514326 3.51533 2.39891E-16 150.77 0.255064 0 2.88773E-16 149.56 1 T DPEATYTTSGGKI 2.4347E-54 269.2 _VLEDDPEATYpTTSGGKIPIR_ VLEDDPEAT(0.052)Y(0.229)T(0.514)T(0.102)S(0.102)GGKIPIR VLEDDPEAT(-9.93)Y(-3.52)T(3.52)T(-7.02)S(-7.02)GGKIPIR 11 3 748.02615 -0.070133 344570 0.1283 0 0 0 0 0 344570 0 2948 465 774 774 6467;6468 7397;7399 65395 40097 Mix4_InSol_Tio2_Reinj_2 4220 65319 40056 Mix4_TiO2_1_4 3218 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.538177 5.99615 0.00192411 -26.5558 2.4347E-54 269.2 1.6167E-05 -47.3737 1.08721E-15 157.36 0.000291328 -35.2115 1.75089E-20 191.59 0.00454708 -22.494 0.0147885 69.135 0.325319 0 2.39891E-16 150.77 0.538177 5.99615 2.88773E-16 149.56 1 T PEATYTTSGGKIP 2.4347E-54 269.2 _VLEDDPEATYTpTSGGKIPIR_ VLEDDPEAT(0.135)Y(0.056)T(0.135)T(0.538)S(0.135)GGKIPIR VLEDDPEAT(-6)Y(-9.83)T(-6)T(6)S(-6)GGKIPIR 12 3 748.02615 -0.17388 490260 0.18256 0 0 0 0 0 0 490260 2949 466 775 775 2005;2006 2270;2272 18389 11164 Mix4_InSol_Tio2_Reinj_1 7782 18375 11159 Mix4_TiO2_Reinj_1_5 6313 P29323;P29323-3;P29323-2 P29323 P29323 >sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 PE=1 SV=5;>sp|P29323-3|EPHB2_HUMAN Isoform 3 of Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2;>sp|P29323-2|EPHB2_HUMAN Isoform Short of Ephrin type-B receptor 2 OS=Homo sapiens GN 0.514625 0.759207 0.0153045 -17.3612 5.25254E-10 126.05 0.16784 -6.87497 3.05227E-06 109.55 0.00703689 -21.0856 4.96298E-10 126.68 0 0 0.474658 0.939494 7.66907E-10 120.84 0.514625 0.759207 0.00155038 79.98 1 T RFLEDDTSDPTYT 4.96298E-10 126.68 _FLEDDpTSDPTYTSALGGKIPIR_ FLEDDT(0.515)S(0.432)DPT(0.003)Y(0.003)T(0.024)S(0.024)ALGGKIPIR FLEDDT(0.76)S(-0.76)DPT(-22.97)Y(-22.45)T(-13.33)S(-13.33)ALGGKIPIR 6 3 826.05963 0.063364 318890 0.83456 0 0 0 0 0 0 318890 2950 466 779 779 2005;2006 2270;2272 18375 11159 Mix4_TiO2_Reinj_1_5 6313 18375 11159 Mix4_TiO2_Reinj_1_5 6313 P29323;P29323-3;P29323-2 P29323 P29323 >sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2 PE=1 SV=5;>sp|P29323-3|EPHB2_HUMAN Isoform 3 of Ephrin type-B receptor 2 OS=Homo sapiens GN=EPHB2;>sp|P29323-2|EPHB2_HUMAN Isoform Short of Ephrin type-B receptor 2 OS=Homo sapiens GN 0.590478 1.59372 0.293716 -3.73469 5.25254E-10 126.05 0.121693 -8.56539 3.05227E-06 109.55 0.590478 1.59372 4.96298E-10 126.68 0 0 0.123876 -7.56389 7.66907E-10 120.84 0.463528 -0.0821889 0.00155038 79.98 1 T DDTSDPTYTSALG CK1;FHA KAPP;PLK1 0.033462 4.96298E-10 126.68 _FLEDDTSDPpTYTSALGGK_ FLEDDTS(0.409)DPT(0.59)YTSALGGK FLEDDT(-34.38)S(-1.59)DPT(1.59)Y(-35.1)T(-44.26)S(-66.13)ALGGK 10 2 998.9248 -0.20914 6450800 16.882 0 0 0 6450800 0 0 0 2951 468 41 41 4736 5379 45148 27627 Mix4_InSol_Tio2_Reinj_1 6854 45147 27626 Mix4_InSol_TiO2_1 6860 P29558;P29558-2 P29558 P29558 >sp|P29558|RBMS1_HUMAN RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 PE=1 SV=3;>sp|P29558-2|RBMS1_HUMAN Isoform 2 of RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 0.232518 0 0.177805 0 0.000562166 92.271 0.232518 0 0.00330012 79.412 1 T APPSPSTTSSNNN CK1;FHA KAPP 0.081 0.000562166 92.271 _QSLVPAHPMAPPpSPSTTSSNNNSSSSSNSGWDQLSK_ QSLVPAHPMAPPS(0.233)PS(0.233)T(0.233)T(0.233)S(0.059)S(0.004)NNNS(0.004)S(0.001)SSSNSGWDQLSK QS(-40.11)LVPAHPMAPPS(0)PS(0)T(0)T(0)S(-5.94)S(-17.35)NNNS(-17.35)S(-22.79)S(-28.05)S(-28.05)S(-33.12)NS(-32.73)GWDQLS(-51.45)K 16 3 1255.5547 -0.061254 0 0 0 0 0 0 0 0 2952 468 42 42 4736 5379 45148 27627 Mix4_InSol_Tio2_Reinj_1 6854 45147 27626 Mix4_InSol_TiO2_1 6860 P29558;P29558-2 P29558 P29558 >sp|P29558|RBMS1_HUMAN RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 PE=1 SV=3;>sp|P29558-2|RBMS1_HUMAN Isoform 2 of RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens GN=RBMS1 0.232518 0 0.177805 0 0.000562166 92.271 0.232518 0 0.00330012 79.412 1 T PPSPSTTSSNNNS 0.000562166 92.271 _QSLVPAHPMAPPpSPSTTSSNNNSSSSSNSGWDQLSK_ QSLVPAHPMAPPS(0.233)PS(0.233)T(0.233)T(0.233)S(0.059)S(0.004)NNNS(0.004)S(0.001)SSSNSGWDQLSK QS(-40.11)LVPAHPMAPPS(0)PS(0)T(0)T(0)S(-5.94)S(-17.35)NNNS(-17.35)S(-22.79)S(-28.05)S(-28.05)S(-33.12)NS(-32.73)GWDQLS(-51.45)K 17 3 1255.5547 -0.061254 0 0 0 0 0 0 0 0 2953 477 190 190 3415 3857 32078 19827 Mix4_TiO2_1_3 3514 32082 19834 Mix4_TiO2_Reinj_1_3 4250 P30291 P30291 P30291 >sp|P30291|WEE1_HUMAN Wee1-like protein kinase OS=Homo sapiens GN=WEE1 PE=1 SV=2 0.999919 40.9094 0.999919 40.9094 0.022624 55.722 0.998386 27.914 0.00770027 61.92 0.998911 29.6252 0.00614354 65.811 0.999749 36.0008 0.0325888 52.567 0.999881 39.2527 0.00614355 65.811 1 T LFDTPHTPKSLLS CDK1;ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 0.00614354 65.811 _LFDTPHpTPK_ LFDTPHT(1)PK LFDT(-40.91)PHT(40.91)PK 7 2 568.26281 0.32108 1271100 170590 212990 0 806930 0 26000 54557 2954 487 69 69 6305 7205 63063 38406 Mix4_TiO2_1_4 4898 63063 38406 Mix4_TiO2_1_4 4898 P31323 P31323 P31323 >sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens GN=PRKAR2B PE=1 SV=3 0.985757 18.4017 0.985757 18.4017 4.14042E-13 154.54 0 0 0.97606 16.1035 9.6403E-09 124.59 1 T AAAGGGTPSKGVN CDK1;CDK2;Proline-directed 0.0057 4.14042E-13 154.54 _TWGDLGAAAGGGpTPSK_ TWGDLGAAAGGGT(0.986)PS(0.014)K T(-144.67)WGDLGAAAGGGT(18.4)PS(-18.4)K 13 2 763.33777 0.64574 373200 85230 0 0 287970 0 0 0 2955 489;765 83;85 85 6517;6518 7456;7458 65843 40338 Mix4_TiO2_Reinj_1_4 4150 65843 40338 Mix4_TiO2_Reinj_1_4 4150 P31483;Q01085 P31483;Q01085 Q01085 >sp|P31483|TIA1_HUMAN Nucleolysin TIA-1 isoform p40 OS=Homo sapiens GN=TIA1 PE=1 SV=3;>sp|Q01085|TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens GN=TIAL1 PE=1 SV=1 0.879164 9.48672 0.861869 8.82903 0.00313545 79.307 0.870485 11.2967 0.0982634 39.063 0.879164 9.48672 0.00237493 124.16 1 T KVNWATTPSSQKK FHA KAPP;Proline-directed 0.05 0.00237493 124.16 _VNWATpTPSSQK_ VNWAT(0.099)T(0.879)PS(0.022)SQK VNWAT(-9.49)T(9.49)PS(-16.04)S(-53.45)QK 6 2 649.79247 0.27231 615910 3.2632 67527 14196 0 534190 0 0 0 2956 491 451 451 6724;6725 7697;7698 68181 41795 Mix4_TiO2_Reinj_1_4 7580 68181 41795 Mix4_TiO2_Reinj_1_4 7580 P31751 P31751 P31751 >sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase OS=Homo sapiens GN=AKT2 PE=1 SV=2 1 76.2971 1 64.8392 2.02797E-15 145.16 1 76.2971 2.60565E-31 201.5 0.998998 31.9774 6.05619E-13 132.33 1 T AQSITITPPDRYD CK2;FHA1 Rad53p;Proline-directed 0.05 2.60565E-31 201.5 _YFDDEFTAQSITIpTPPDR_ YFDDEFTAQSITIT(1)PPDR Y(-201.5)FDDEFT(-189.09)AQS(-166.98)IT(-76.3)IT(76.3)PPDR 14 3 732.65594 0.49759 4770100 521740 0 0 4052600 195770 0 0 2957 494 100 100 2674 3045 25063 15499 Mix4_InSol_Tio2_Reinj_2 3259 25077 15516 Mix4_TiO2_Reinj_1_4 4084 P31943;P55795 P31943 P31943 >sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens GN=HNRNPH1 PE=1 SV=4;>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens GN=HNRNPH2 PE=1 SV=1 0.483871 0 0.1427 -7.58787 1.90422E-20 191.28 0 0 0.018118 -17.3394 8.65451E-26 202.3 0 0 0.416325 1.54291 1.18713E-25 197.73 0.483871 0 8.14919E-20 178.35 1 T DWVLKHTGPNSPD NEK6 0.076 8.65451E-26 202.3 _HpTGPNSPDTANDGFVR_ HT(0.484)GPNS(0.484)PDT(0.032)ANDGFVR HT(0)GPNS(0)PDT(-11.76)ANDGFVR 2 3 588.91609 0.30832 0 0 0 0 0 0 0 0 0 2958 494 107 107 2674 3045 25079 15518 Mix4_TiO2_Reinj_1_6 3532 25077 15516 Mix4_TiO2_Reinj_1_4 4084 P31943;P55795 P31943 P31943 >sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens GN=HNRNPH1 PE=1 SV=4;>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens GN=HNRNPH2 PE=1 SV=1 0.938497 11.8354 0.498289 0 1.90422E-20 191.28 0 0 0.938497 11.8354 8.65451E-26 202.3 0 0 0.291838 -1.54291 1.18713E-25 197.73 0.87584 8.48442 8.14919E-20 178.35 1 T GPNSPDTANDGFV CK1;CK2;FHA1 Rad53p 0.059 8.65451E-26 202.3 _HTGPNSPDpTANDGFVR_ HTGPNS(0.062)PDT(0.938)ANDGFVR HT(-68.36)GPNS(-11.84)PDT(11.84)ANDGFVR 9 2 882.8705 0.30775 5449300 17.633 0 0 0 4756900 0 0 692400 2959 506 485 485 1312 1481 12304 7512 Mix4_TiO2_Reinj_1_3 7449 12304 7512 Mix4_TiO2_Reinj_1_3 7449 P34947;P43250-2;P43250 P34947 P34947 >sp|P34947|GRK5_HUMAN G protein-coupled receptor kinase 5 OS=Homo sapiens GN=GRK5 PE=1 SV=1;>sp|P43250-2|GRK6_HUMAN Isoform GRK6B of G protein-coupled receptor kinase 6 OS=Homo sapiens GN=GRK6;>sp|P43250|GRK6_HUMAN G protein-coupled receptor kinase 6 OS=Ho 0.617328 2.0769 0 0 0.617328 2.0769 0.000314717 114.53 1 T DIEQFSTVKGVNL 0.000314717 114.53 _DVLDIEQFSpTVK_ DVLDIEQFS(0.383)T(0.617)VK DVLDIEQFS(-2.08)T(2.08)VK 10 2 737.34727 0.40243 432330 0 0 0 432330 0 0 0 2960 518 436 436 5564 6339;6340 54466 33346 Mix4_TiO2_Reinj_1_5 2519 54465 33345 Mix4_TiO2_Reinj_1_1 2097 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 0.76743 4.437 0.0273933 -14.7798 4.27801E-06 109.99 0.76743 4.437 9.08297E-10 134.9 0.557501 1.97885 0.846307 18.987 0.675265 5.92641 0.822766 19.667 2 T SPGSTPTTPTSSQ CK1 0.081 9.08297E-10 134.9 _pSPGSTPpTTPTSSQAPQK_ S(0.448)PGS(0.534)T(0.019)PT(0.767)T(0.202)PT(0.025)S(0.004)SQAPQK S(0)PGS(0)T(-15.05)PT(4.44)T(-4.44)PT(-13.54)S(-21.21)S(-35.81)QAPQK 7 2 916.37918 0.52858 121330 0 0 0 87712 0 17020 16599 2961 518 439 439 5564 6339;6340 54464 33343 Mix4_TiO2_1_1 1751 54465 33345 Mix4_TiO2_Reinj_1_1 2097 P35658-5;P35658-3;P35658;P35658-4;P35658-2 P35658-5 P35658-5 >sp|P35658-5|NU214_HUMAN Isoform 5 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658-3|NU214_HUMAN Isoform 3 of Nuclear pore complex protein Nup214 OS=Homo sapiens GN=NUP214;>sp|P35658|NU214_HUMAN Nuclear pore complex protein Nup2 0.815066 7.40864 0.815066 7.40864 4.27801E-06 109.99 0.761518 6.86634 9.08297E-10 134.9 0.0391557 -17.584 0.846307 18.987 0.0370883 -19.6669 0.822766 19.667 2 T STPTTPTSSQAPQ 9.08297E-10 134.9 _SPGpSTPTTPpTSSQAPQK_ S(0.348)PGS(0.64)T(0.012)PT(0.027)T(0.149)PT(0.815)S(0.009)SQAPQK S(-2.66)PGS(2.66)T(-17.32)PT(-14.78)T(-7.41)PT(7.41)S(-19.79)S(-41.94)QAPQK 10 2 916.37918 0.41201 273480 61612 0 0 211870 0 0 0 2962 521 17 17 3169;4927 3597;5601 47294 28881 Mix4_TiO2_Reinj_1_4 7736 47295 28884 Mix4_TiO2_Reinj_1_4 7746 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.705181 4.89932 0.102693 -5.65648 1.06584E-12 128.76 0 0 0.705181 4.89932 6.39521E-27 166.38 0 0 0.0752882 -9.17872 2.76751E-05 98.157 0.201976 0 1.70775 29.813 1 T ALTINPTIAEGPS CK2 0.117 6.39521E-27 166.38 _RKPVLPALTINPpTIAEGPSPTSEGASEANLVDLQK_ RKPVLPALT(0.004)INPT(0.705)IAEGPS(0.228)PT(0.052)S(0.01)EGASEANLVDLQK RKPVLPALT(-22.18)INPT(4.9)IAEGPS(-4.9)PT(-11.31)S(-18.39)EGAS(-55.07)EANLVDLQK 13 4 924.23293 0.2863 11797000 1.0624 0 0 0 11797000 0 0 0 2963 521 25 25 3169;4927 3597;5601 30047 18694 Mix4_TiO2_Reinj_1_4 8047 47295 28884 Mix4_TiO2_Reinj_1_4 7746 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.770962 7.99112 0.519226 0.558495 1.06584E-12 128.76 0 0 0.770962 7.99112 6.39521E-27 166.38 0 0 0.62316 7.57485 2.76751E-05 98.157 0.201976 0 1.70775 29.813 1 T AEGPSPTSEGASE 6.39521E-27 166.38 _KPVLPALTINPTIAEGPSPpTSEGASEANLVDLQK_ KPVLPALTINPTIAEGPS(0.103)PT(0.771)S(0.122)EGAS(0.003)EANLVDLQK KPVLPALT(-106.11)INPT(-79.58)IAEGPS(-8.73)PT(7.99)S(-7.99)EGAS(-23.59)EANLVDLQK 20 3 1179.9411 -0.12586 2405700 0.21665 98419 0 0 1549900 0 757370 0 2964 521;778 230;226 230 3325 3761;3762 31413 19468 Mix4_InSol_Tio2_Reinj_3 4087 31417 19473 Mix4_TiO2_Reinj_1_4 8785 P36507;Q02750 P36507;Q02750 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1;>sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2 0.455882 2.24194 0.0050111 -22.9788 1.58563E-25 175.6 0.20088 -5.99675 5.90012E-39 200.95 0 0 0.181702 -6.53547 3.24595E-24 168.6 0.455882 2.24194 0.000145158 94.198 1 T ANSFVGTRSYMAP;ANSFVGTRSYMSP 5.90012E-39 200.95 _LCDFGVSGQLIDSMANSFVGpTR_ LCDFGVSGQLIDS(0.272)MANS(0.272)FVGT(0.456)R LCDFGVS(-50.07)GQLIDS(-2.24)MANS(-2.24)FVGT(2.24)R 21 2 1227.5451 1.126 0 0 0 0 0 0 0 0 2965 521 394 394 3609;3610;6080;6081 4069;4070;6935;6936 33959 20962 Mix4_InSol_TiO2_3 2302 33923 20897 Mix4_InSol_Tio2_Reinj_1 2565 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.999334 31.7705 0.732431 4.3733 0.00088641 82.133 0.978481 16.5773 0.0027064 101.98 0.985466 18.3126 0.0027064 101.98 0.952455 13.0174 0.0389436 50.555 0.999334 31.7705 0.00207898 95.926 0.999158 30.7499 0.00310136 105.29 1 T RLNQPGTPTRTAV CDK1;CDK2;ERK/MAPK;Proline-directed 0.0025 0.00310136 105.29 _LNQPGpTPTRTAV_ LNQPGT(0.999)PT(0.001)RTAV LNQPGT(31.77)PT(-31.77)RT(-61.16)AV 6 2 667.82684 -0.42344 65929000 6839400 7000100 0 28974000 83781 12495000 10537000 2966 521 396 396 3609;3610;6080;6081 4069;4070;6935;6936 60073 36410 Mix4_InSol_Tio2_Reinj_2 3182 33923 20897 Mix4_InSol_Tio2_Reinj_1 2565 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.913824 10.3753 0.395748 -1.83799 0.00088641 82.133 0.432579 -1.1784 0.0027064 101.98 0.445843 -0.94451 0.0027064 101.98 0.131458 -8.20004 0.0389436 50.555 0.819495 6.57056 0.00207898 95.926 0.913824 10.3753 0.00310136 105.29 1 T NQPGTPTRTAV__ FHA KAPP 0.155 0.00310136 105.29 _TLRLNQPGTPpTR_ T(0.002)LRLNQPGT(0.084)PT(0.914)R T(-25.88)LRLNQPGT(-10.38)PT(10.38)R 11 2 717.36666 0.13008 1554600 0 0 0 0 0 1372900 181700 2967 521 398 398 3610;6081 4070;6936 60081 36411 Mix4_InSol_TiO2_1 5301 33964 20971 Mix4_InSol_Tio2_Reinj_3 2184 P36507 P36507 P36507 >sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1 0.337565 0 0.337565 0 0.00398802 88.603 0.199922 -2.11424 0.00269859 93.231 1 T PGTPTRTAV____ 0.00269859 93.231 _TLRLNQPGTPpTRTAV_ TLRLNQPGT(0.325)PT(0.338)RT(0.338)AV T(-57.63)LRLNQPGT(-0.17)PT(0)RT(0)AV 13 3 568.9646 0.12166 0 0 0 0 0 0 0 0 2968 544;545 74;74 74 2360 2670 21843 13575 Mix4_TiO2_Reinj_1_4 5527 21843 13575 Mix4_TiO2_Reinj_1_4 5527 P42166;P42167;P42167-2 P42166;P42167 P42167 >sp|P42166|LAP2A_HUMAN Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167-2|LAP2B_HUMAN Isoform Gamma of 0.999992 54.3578 0.443798 3.12237 9.26824E-05 93.632 0 0 0.999992 54.3578 1.02746E-11 122.03 0.992486 24.0545 0.0203086 63.562 0.65736 5.86679 0.910148 35.034 1 T DEEREPTPVLGSG CAMK2;FHA2 Rad53p;Proline-directed 0.042 1.02746E-11 122.03 _GPPDFSSDEEREPpTPVLGSGAAAAGR_ GPPDFSSDEEREPT(1)PVLGSGAAAAGR GPPDFS(-58.88)S(-54.36)DEEREPT(54.36)PVLGS(-55.87)GAAAAGR 14 3 884.06421 0.13457 1342100 0 0 0 1079300 0 140190 122680 2969 544;545 160;160 160 5762 6565 56657 34572 Mix4_InSol_TiO2_2 3876 56660 34575 Mix4_TiO2_1_4 4140 P42166;P42167;P42167-2 P42166;P42167 P42167 >sp|P42166|LAP2A_HUMAN Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167-2|LAP2B_HUMAN Isoform Gamma of 0.352596 0 0.297172 -1.35149 1.0688E-15 157.67 0.27393 -1.63764 0.609414 24.872 0.290994 -1.57305 3.91714E-06 112.62 0.352596 0 4.55187E-09 131.34 0.293173 -1.49515 1.09732E-05 102.74 1 T TESRSSTPLPTIS CAMK2;Polo box;Proline-directed 0.00405 1.0688E-15 157.67 _SpSTPLPTISSSAENTR_ S(0.287)S(0.353)T(0.353)PLPT(0.002)IS(0.002)S(0.002)S(0.002)AENT(0.002)R S(-0.89)S(0)T(0)PLPT(-23.62)IS(-23.62)S(-23.62)S(-23.62)AENT(-23.62)R 3 2 864.39601 0.19451 0 0 0 0 0 0 0 0 2970 545 208 208 310 353 2920 1778 Mix4_TiO2_1_4 2191 2924 1785 Mix4_TiO2_Reinj_1_4 2833 P42167;P42167-2 P42167 P42167 >sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO PE=1 SV=2;>sp|P42167-2|LAP2B_HUMAN Isoform Gamma of Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens GN=TMPO 0.999993 51.7905 0.999993 51.7905 0.0767442 51.79 0.999917 40.8027 0.108984 46.832 0.999991 50.7085 0.017976 64.934 0.999991 50.589 0.0340451 58.357 0.999847 38.1433 0.196222 38.143 1 T LKGRAKTPVTLKQ CAMK2;Proline-directed 0.042 0.017976 64.934 _AKpTPVTLK_ AKT(1)PVTLK AKT(51.79)PVT(-51.79)LK 3 2 469.25954 -0.25201 1959200 202500 85602 0 1153600 0 301660 215840 2971 547 2471 2471 3235;6008;6009 3667;6848;6849;6850 59336 36039 Mix4_TiO2_Reinj_1_1 6920 30612 19025 Mix4_TiO2_Reinj_1_1 6824 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.762472 6.17911 0.0233528 -16.0645 0.173382 53.045 0 0 0.762472 6.17911 5.81466E-12 128.7 0 0 0 0 1 T EPAHKKTGTTVPE 5.81466E-12 128.7 _pTGTTVPESIHSFIGDGLVKPEALNKK_ T(0.762)GT(0.184)T(0.041)VPES(0.012)IHS(0.001)FIGDGLVKPEALNKK T(6.18)GT(-6.18)T(-12.71)VPES(-18)IHS(-29.73)FIGDGLVKPEALNKK 1 4 705.36512 -0.69776 277060 0 0 0 277060 0 0 0 2972 547 2473 2473 3235;6008;6009 3667;6848;6849;6850 30612 19025 Mix4_TiO2_Reinj_1_1 6824 30612 19025 Mix4_TiO2_Reinj_1_1 6824 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.759718 8.00935 0.0264858 -15.5178 0.173382 53.045 0 0 0.759718 8.00935 5.81466E-12 128.7 0 0 0 0 1 T AHKKTGTTVPESI 5.81466E-12 128.7 _KTGpTTVPESIHSFIGDGLVKPEALNK_ KT(0.116)GT(0.76)T(0.12)VPES(0.004)IHSFIGDGLVKPEALNK KT(-8.18)GT(8.01)T(-8.01)VPES(-22.76)IHS(-32.06)FIGDGLVKPEALNK 4 3 940.15107 -0.080315 349900 0 0 0 349900 0 0 0 2973 547 2474 2474 3235;6008;6009 3667;6848;6849;6850 30611 19024 Mix4_TiO2_Reinj_1_1 6816 30612 19025 Mix4_TiO2_Reinj_1_1 6824 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.409523 0 0.00608314 -21.9066 0.173382 53.045 0 0 0.409523 0 5.81466E-12 128.7 0 0 0 0 1 T HKKTGTTVPESIH CK2 0.117 5.81466E-12 128.7 _KTGpTTVPESIHSFIGDGLVKPEALNK_ KT(0.023)GT(0.41)T(0.41)VPES(0.158)IHSFIGDGLVKPEALNK KT(-12.54)GT(0)T(0)VPES(-4.13)IHS(-43.14)FIGDGLVKPEALNK 5 4 705.36512 -0.15981 0 0 0 0 0 0 0 0 2974 547 1262 1262 3477 3924 32776 20310 Mix4_TiO2_Reinj_1_1 4896 32776 20310 Mix4_TiO2_Reinj_1_1 4896 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.994183 22.3278 0 0 0.994183 22.3278 0.00604271 63.221 0 0 0 0 1 T KKLHVSTINLQKA FHA2 Rad53p 0.114 0.00604271 63.221 _LHVSpTINLQK_ LHVS(0.006)T(0.994)INLQK LHVS(-22.33)T(22.33)INLQK 5 2 616.82357 -0.15324 48439 0 0 0 48439 0 0 0 2975 547 2446 2446 5950;6204;6205 6786;6787;7087;7088;7089 58709 35592 Mix4_TiO2_1_1 5911 61495 37270 Mix4_TiO2_1_1 5909 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.648141 5.00274 0.648141 5.00274 1.36597E-25 160.21 0.449375 -0.861062 0.000152987 90.238 0.44188 -1.01155 1.61746E-25 157.31 0 0 0.0175583 -13.3491 1.63028 25.351 0.225823 -0.447727 0.000169646 89.325 1 T KRSRTRTDSYSAG CAMK2;PKA/AKT 0.00111111 1.36597E-25 160.21 _pTDSYSAGQSVEILDGVELGEPAHK_ T(0.648)DS(0.205)Y(0.02)S(0.105)AGQS(0.022)VEILDGVELGEPAHK T(5)DS(-5)Y(-15.09)S(-7.89)AGQS(-14.78)VEILDGVELGEPAHK 1 3 861.39345 0.25069 61365 61365 0 0 0 0 0 0 2976 547 2444 2444 6204;6205 7087;7088;7089 61504 37285 Mix4_TiO2_Reinj_1_6 6098 61495 37270 Mix4_TiO2_1_1 5909 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.637411 6.58495 0.250289 -1.16681 1.36597E-25 160.21 0.29791 0 0.000152987 90.238 0.637411 6.58495 1.61746E-25 157.31 0 0 0.0483774 -8.9475 1.63028 25.351 0.250346 0.447727 0.000169646 89.325 1 T GNKRSRTRTDSYS CAMK2;CK2;FHA1 Rad53p;PKA;PKA/AKT 0.00111111 1.36597E-25 160.21 _pTRTDSYSAGQSVEILDGVELGEPAHK_ T(0.637)RT(0.14)DS(0.073)Y(0.073)S(0.073)AGQS(0.003)VEILDGVELGEPAHK T(6.58)RT(-6.58)DS(-9.39)Y(-9.39)S(-9.39)AGQS(-23.83)VEILDGVELGEPAHK 1 3 947.10971 -0.11659 70683 0 0 0 70683 0 0 0 2977 552 1050 1050 243 280 2452 1552 Mix4_TiO2_1_5 5141 2453 1554 Mix4_TiO2_Reinj_1_5 5921 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.261085 0 0.261085 0 0.0882661 54.011 0.25 0 0.0142496 64.129 1 T PQVPLPTSSISPA FHA2 Rad53p 0.114 0.0142496 64.129 _AGRPVM(ox)PPPQVPLPpTSSISPAK_ AGRPVMPPPQVPLPT(0.261)S(0.261)S(0.261)IS(0.217)PAK AGRPVMPPPQVPLPT(0)S(0)S(0)IS(-0.81)PAK 15 3 775.06751 0.10059 0 0 0 0 0 0 0 0 2978 552 784 784 5530 6298;6299 54102 33120 Mix4_InSol_TiO2_2 3312 54101 33119 Mix4_InSol_TiO2_1 4460 P42684;P42684-3;P42684-2 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.221668 0 0 0 0 0 0.0566493 -10.044 3.42094E-12 139.16 0.221668 0 5.82983E-16 165.97 0.052175 -9.51512 6.05756E-06 109.62 1 T FPRSNSTSSMSSG CK1 0.081 5.82983E-16 165.97 _SNpSTSSMSSGLPEQDR_ S(0.198)NS(0.222)T(0.222)S(0.09)S(0.09)MS(0.09)S(0.09)GLPEQDR S(-0.49)NS(0)T(0)S(-3.93)S(-3.93)MS(-3.93)S(-3.93)GLPEQDR 4 2 881.85111 0.68579 0 0 0 0 0 0 0 0 2979 552 815 815 6299 7197;7199 62994 38370 Mix4_InSol_TiO2_1 3422 63001 38380 Mix4_TiO2_Reinj_1_5 3230 P42684;P42684-3;P42684-2;P42684-4 P42684 P42684 >sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1;>sp|P42684-3|ABL2_HUMAN Isoform IC of Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2;>sp|P42684-2|ABL2_HUMAN Isoform IA of Tyrosine-protein kinase ABL2 OS=Homo sapie 0.494098 0 0.0200059 -16.7801 1.64222E-06 120.21 0.40163 -1.28649 0.0286081 59.088 0.0803756 -10.491 9.83691E-09 140.79 0 0 0.494098 0 0.000179347 102.71 3.22433E-06 -54.3659 0.00633133 76.759 1 T KLQLERTVSTSSQ NEK6;PLK1 0.033462 9.83691E-09 140.79 _pTVSTSSQPEENVDR_ T(0.494)VS(0.494)T(0.011)S(0.001)SQPEENVDR T(0)VS(0)T(-16.57)S(-27.42)S(-43.75)QPEENVDR 1 2 814.84361 0.73857 0 0 0 0 0 0 0 0 0 2980 563 113 113 3763;3764 4247;4248 35605 22007 Mix4_TiO2_1_4 5293 35589 21989 Mix4_TiO2_Reinj_1_2 5639 P45880;P45880-1;P45880-2 P45880 P45880 >sp|P45880|VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2 PE=1 SV=2;>sp|P45880-1|VDAC2_HUMAN Isoform 1 of Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2;>sp|P45880-2|VDAC2_HUMAN Isofor 0.898478 10.2826 0.898478 10.2826 8.01356E-09 158.97 0.312965 0.13344 0.07179 46.424 0.49943 0 9.1341E-14 189.65 0.444295 0 2.03911E-06 149.58 0.150606 -2.84608 0.00883678 74.641 1 T KLTFDTTFSPNTG PLK1 0.033462 9.1341E-14 189.65 _LTFDTpTFSPNTGKK_ LTFDTT(0.898)FS(0.084)PNT(0.017)GKK LT(-60.16)FDT(-45.98)T(10.28)FS(-10.28)PNT(-17.15)GKK 6 2 818.88455 -0.083672 294380 294380 0 0 0 0 0 0 2981 563 118 118 3763;3764 4247;4248 35599 21997 Mix4_InSol_Tio2_Reinj_1 6486 35589 21989 Mix4_TiO2_Reinj_1_2 5639 P45880;P45880-1;P45880-2 P45880 P45880 >sp|P45880|VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2 PE=1 SV=2;>sp|P45880-1|VDAC2_HUMAN Isoform 1 of Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2;>sp|P45880-2|VDAC2_HUMAN Isofor 0.957912 13.6383 0.453005 0.772879 8.01356E-09 158.97 0.127846 -3.88808 0.07179 46.424 0.558829 4.10995 9.1341E-14 189.65 0.115762 -4.50125 2.03911E-06 149.58 0.957912 13.6383 0.00883678 74.641 1 T TTFSPNTGKKSGK CK1 0.081 9.1341E-14 189.65 _LTFDTTFSPNpTGKK_ LTFDTT(0.001)FS(0.041)PNT(0.958)GKK LT(-59.44)FDT(-53.17)T(-31.79)FS(-13.64)PNT(13.64)GKK 11 2 818.88455 -0.23261 541780 0 0 0 98627 0 0 443160 2982 563 68 68 6634 7594 67258 41304 Mix4_TiO2_1_2 1694 67260 41307 Mix4_TiO2_Reinj_1_2 2289 P45880;P45880-1;P45880-2 P45880 P45880 >sp|P45880|VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2 PE=1 SV=2;>sp|P45880-1|VDAC2_HUMAN Isoform 1 of Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2;>sp|P45880-2|VDAC2_HUMAN Isofor 0.999954 44.8493 0.999954 44.8493 0.0968383 48.7 0.990999 20.5431 0.235789 35.875 0.999916 40.7708 0.00630614 79.143 0 0 1 T TGKVTGTLETKYK 0.00630614 79.143 _VTGpTLETK_ VTGT(1)LETK VT(-44.85)GT(44.85)LET(-48.7)K 4 2 464.72299 -0.42302 241620 13.647 33127 21740 0 186750 0 0 0 2983 567 977 977 5840 6659;6660 57581 35050 Mix4_TiO2_Reinj_1_5 4702 57581 35050 Mix4_TiO2_Reinj_1_5 4702 P46019 P46019 P46019 >sp|P46019|KPB2_HUMAN Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens GN=PHKA2 PE=1 SV=1 0.19678 0 0.19678 0 3.50864E-07 101.08 1 T RPIHSSTSSPTIS 3.50864E-07 101.08 _SVRPIHpSSTSSPTISIHEVGHTGVTK_ S(0.01)VRPIHS(0.197)S(0.197)T(0.197)S(0.197)S(0.197)PT(0.006)ISIHEVGHTGVTK S(-13.02)VRPIHS(0)S(0)T(0)S(0)S(0)PT(-14.95)IS(-66.18)IHEVGHT(-101.08)GVT(-101.08)K 9 3 932.1343 -0.0071434 0 0 0 0 0 0 0 0 2984 568 976 976 5841 6661 57591 35061 Mix4_TiO2_Reinj_1_5 6368 57591 35061 Mix4_TiO2_Reinj_1_5 6368 P46020;P46020-2 P46020 P46020 >sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P46020-2|KPB1_HUMAN Isoform C of Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens 0.857239 10.4707 0.207919 -5.04377 0.00305729 77.247 0 0 0.857239 10.4707 3.64191E-07 106.56 0 0 0.0362474 -13.2448 0.0177996 64.242 0.0479581 -8.95656 1.16456 29.669 1 T ERSVRPTDSNVSP PKA 0.042 3.64191E-07 106.56 _SVRPpTDSNVSPAISIHEIGAVGATK_ S(0.059)VRPT(0.857)DS(0.077)NVS(0.007)PAISIHEIGAVGATK S(-11.62)VRPT(10.47)DS(-10.47)NVS(-21.03)PAIS(-72.41)IHEIGAVGAT(-106.56)K 5 3 862.76896 -0.040319 472290 0 0 0 472290 0 0 0 2985 568 995 995 5841 6661 57589 35058 Mix4_TiO2_1_5 5520 57591 35061 Mix4_TiO2_Reinj_1_5 6368 P46020;P46020-2 P46020 P46020 >sp|P46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens GN=PHKA1 PE=1 SV=2;>sp|P46020-2|KPB1_HUMAN Isoform C of Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens 0.489595 0.415697 0.489595 0.415697 0.00305729 77.247 0 0 1.31805E-09 -85.7552 3.64191E-07 106.56 0 0 3.72775E-07 -63.1231 0.0177996 64.242 0.000407035 -29.6689 1.16456 29.669 1 T IGAVGATKTERTG CK2 0.117 3.64191E-07 106.56 _SVRPTDSNVSPAISIHEIGAVGApTK_ S(0.016)VRPT(0.016)DS(0.016)NVS(0.016)PAIS(0.445)IHEIGAVGAT(0.49)K S(-14.76)VRPT(-14.76)DS(-14.76)NVS(-14.76)PAIS(-0.42)IHEIGAVGAT(0.42)K 24 4 647.32854 0.29267 0 0 0 0 0 0 0 0 2986 570 117 117 403 461 3818 2269 Mix4_TiO2_1_5 3266 3821 2272 Mix4_TiO2_Reinj_1_5 3706 P46379-3;P46379;P46379-2 P46379-3 P46379-3 >sp|P46379-3|BAT3_HUMAN Isoform 3 of Large proline-rich protein BAT3 OS=Homo sapiens GN=BAT3;>sp|P46379|BAT3_HUMAN Large proline-rich protein BAT3 OS=Homo sapiens GN=BAT3 PE=1 SV=2;>sp|P46379-2|BAT3_HUMAN Isoform 2 of Large proline-rich protein BAT3 OS=Hom 0.415594 0 0.415594 0 0.478274 52.093 0.3517 0 5.54437E-13 130.9 0 0 0 0 1 T GGSPPGTRGPGAS 5.54437E-13 130.9 _APPQTHLPSGASSGTGSASATHGGGpSPPGTR_ APPQT(0.02)HLPS(0.02)GAS(0.02)S(0.02)GT(0.02)GS(0.02)AS(0.024)AT(0.024)HGGGS(0.416)PPGT(0.416)R APPQT(-13.15)HLPS(-13.15)GAS(-13.15)S(-13.15)GT(-13.15)GS(-13.15)AS(-12.37)AT(-12.37)HGGGS(0)PPGT(0)R 30 4 717.07825 -0.181 0 0 0 0 0 0 0 0 2987 571 37 37 4890 5561 46965 28737 Mix4_TiO2_1_6 6225 46966 28738 Mix4_TiO2_Reinj_1_6 7127 P46695 P46695 P46695 >sp|P46695|IEX1_HUMAN Radiation-inducible immediate-early gene IEX-1 OS=Homo sapiens GN=IER3 PE=1 SV=3 0.5 0 0.5 0 1.71711 12.752 0.213544 -5.66186 2.44124E-11 124.49 1 T SGPEIFTFDPLPE 2.44124E-11 124.49 _RGpSGPEIFTFDPLPEPAAAPAGR_ RGS(0.5)GPEIFT(0.5)FDPLPEPAAAPAGR RGS(0)GPEIFT(0)FDPLPEPAAAPAGR 9 3 811.7248 0.18432 34585 34585 0 0 0 0 0 0 2988 584 415 415 1626;6316 1826;7216 14949 9044 Mix4_TiO2_Reinj_1_3 5273 14951 9046 Mix4_TiO2_Reinj_1_5 5309 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 0.855191 8.20326 0 0 0.855191 8.20326 2.1698E-16 137.88 0.0100121 -19.92 0.000842138 84.515 0.0364593 -14.2084 0.143981 45.071 1 T YGHREKTYSECED CAMK2;CK2;PLK1 0.033462 2.1698E-16 137.88 _EKpTYSECEDGTYSPEISWHHR_ EKT(0.855)Y(0.015)S(0.129)ECEDGTYSPEISWHHR EKT(8.2)Y(-17.43)S(-8.2)ECEDGT(-49.8)Y(-58.36)S(-70.71)PEIS(-74.56)WHHR 3 3 897.69876 0.30193 469260 0 0 0 469260 0 0 0 2989 584 436 436 2494 2834 23468 14604 Mix4_InSol_TiO2_2 1347 23469 14605 Mix4_InSol_Tio2_Reinj_1 1884 P48651 P48651 P48651 >sp|P48651|PTSS1_HUMAN Phosphatidylserine synthase 1 OS=Homo sapiens GN=PTDSS1 PE=1 SV=1 0.49573 0.229108 0 0 0 0 0.49573 0.229108 0.0147213 63.597 0.344426 -1.21268 0.000495364 82.959 1 T WHHRKGTKGSEDS CAMK2;FHA KAPP;PKA 0.004788 0.000495364 82.959 _GpTKGSEDSPPKHAGNNESHSSR_ GT(0.496)KGS(0.027)EDS(0.47)PPKHAGNNES(0.002)HS(0.002)S(0.002)R GT(0.23)KGS(-12.58)EDS(-0.23)PPKHAGNNES(-23.48)HS(-23.48)S(-23.48)R 2 3 787.00681 -0.54314 0 0 0 0 0 0 0 0 2990 585 349 349 65;67;4593 77;80;5214 685 452 Mix4_TiO2_Reinj_1_2 1498 678 441 Mix4_TiO2_1_4 1389 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.999923 41.1333 0.998059 27.1116 1.54851E-77 283.56 0.915686 10.3585 2.85475E-32 181.48 0.999923 41.1333 3.27832E-65 263.47 0.994751 22.7767 8.47293E-39 203.67 0.994249 22.3772 2.05083E-32 185.36 1 T QGQQAQTPTGKQT Proline-directed 0.05 1.54851E-77 283.56 _AAQQAASSSGQGQQAQpTPTGK_ AAQQAASSSGQGQQAQT(1)PTGK AAQQAAS(-174.9)S(-153.79)S(-140.67)GQGQQAQT(41.13)PT(-41.13)GK 17 2 1041.466 -0.026824 12295000 0.14242 2897700 62842 0 7415200 0 1033700 885670 2991 585 355 355 67;4749 80;5395 799 542 Mix4_InSol_TiO2_1 2026 45313 27719 Mix4_InSol_Tio2_Reinj_1 1141 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.243579 0 0 0 0.243579 0 0.553451 43.01 4.47297E-06 -53.4932 0.0273729 53.493 1 T TPTGKQTDKTKSN 0.0273729 53.493 _AAQQAASSSGQGQQAQTPTGKQpTDKTK_ AAQQAAS(0.016)S(0.014)S(0.078)GQGQQAQT(0.19)PT(0.215)GKQT(0.244)DKT(0.244)K AAQQAAS(-11.75)S(-12.47)S(-4.92)GQGQQAQT(-1.09)PT(-0.55)GKQT(0)DKT(0)K 23 3 928.43671 0.010515 0 0 0 0 0 0 0 0 2992 585 358 358 67;4749 80;5395 799 542 Mix4_InSol_TiO2_1 2026 45313 27719 Mix4_InSol_Tio2_Reinj_1 1141 P48729-2;P48729 P48729-2 P48729-2 >sp|P48729-2|KC1A_HUMAN Isoform 2 of Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1;>sp|P48729|KC1A_HUMAN Casein kinase I isoform alpha OS=Homo sapiens GN=CSNK1A1 PE=1 SV=2 0.243579 0 0 0 0.243579 0 0.553451 43.01 0.000179306 -37.4633 0.0273729 53.493 1 T GKQTDKTKSNMKG 0.0273729 53.493 _AAQQAASSSGQGQQAQTPTGKQpTDKTK_ AAQQAAS(0.016)S(0.014)S(0.078)GQGQQAQT(0.19)PT(0.215)GKQT(0.244)DKT(0.244)K AAQQAAS(-11.75)S(-12.47)S(-4.92)GQGQQAQT(-1.09)PT(-0.55)GKQT(0)DKT(0)K 26 3 928.43671 0.010515 0 0 0 0 0 0 0 0 2993 586 329 329 2315;2316 2618;2619;2620;2621 21467 13155 Mix4_TiO2_Reinj_1_4 4186 21446 13146 Mix4_TiO2_Reinj_1_4 3045 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.66646 2.57489 0.613716 2.01004 0.0978909 38.91 0 0 0.66646 2.57489 0.00455417 69.784 0.499997 0 0.0422994 49.492 0.499678 0 0.0422995 49.492 2 T TRGLPSTASGRLR NEK6 0.076 0.00455417 69.784 _GLPSpTApSGRLR_ GLPS(0.397)T(0.666)AS(0.937)GRLR GLPS(-2.57)T(2.57)AS(9.81)GRLR 5 2 637.78633 0.4299 1035800 0 0 0 756670 0 279120 0 2994 586 344 344 2504;2505;3694;3695 2844;2845;2846;2847;2848;4165;4166;4167 23583 14673 Mix4_TiO2_1_4 4684 34800 21596 Mix4_TiO2_Reinj_1_4 4587 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.381794 0 0.381794 0 0.0245207 68.767 0.027653 -13.5366 0.907724 42.156 0.0691165 -6.58558 4.82887E-45 200.14 0.128441 -0.919326 0.0365223 63.425 0.188913 0 0.0387768 68.836 1 T QEVAPPTPLTPTS ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.82887E-45 200.14 _GTQEVAPPpTPLTPTSHTANTSPRPVSGMER_ GTQEVAPPT(0.382)PLT(0.382)PT(0.096)S(0.096)HT(0.026)ANT(0.008)S(0.008)PRPVS(0.002)GMER GT(-35.33)QEVAPPT(0)PLT(0)PT(-5.98)S(-5.98)HT(-11.65)ANT(-17)S(-17)PRPVS(-22.01)GMER 9 4 799.88277 0.0065367 0 0 0 0 0 0 0 0 2995 586 347 347 2504;2505;3694;3695 2844;2845;2846;2847;2848;4165;4166;4167 34800 21596 Mix4_TiO2_Reinj_1_4 4587 34800 21596 Mix4_TiO2_Reinj_1_4 4587 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.999736 36.4208 0.399393 5.75251 0.0245207 68.767 0.624312 6.93376 0.907724 42.156 0.999736 36.4208 4.82887E-45 200.14 0.286693 0 0.0365223 63.425 0.481957 5.63896 1.04861 39.205 1 T APPTPLTPTSHTA ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 4.82887E-45 200.14 _LRGTQEVAPPTPLpTPTSHTANTSPR_ LRGTQEVAPPTPLT(1)PTSHTANTSPR LRGT(-151.87)QEVAPPT(-92.22)PLT(36.42)PT(-44.51)S(-36.42)HT(-64.37)ANT(-95.72)S(-101.09)PR 14 3 903.78338 -0.73424 543920 0 61289 0 482640 0 0 0 2996 586 349 349 2504;2505;3694;3695 2844;2845;2846;2847;2848;4165;4166;4167 23580 14670 Mix4_InSol_Tio2_Reinj_1 5674 34800 21596 Mix4_TiO2_Reinj_1_4 4587 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.384443 0 0.151865 -2.44538 0.0245207 68.767 0.126481 -6.93376 0.907724 42.156 0.308015 0 3.51356E-11 118.78 0.286693 0 0.0365223 63.425 0.384443 0 0.0387768 68.836 1 T PTPLTPTSHTANT NEK6 0.076 4.82887E-45 200.14 _GTQEVAPPTPLTPpTSHTANTSPRPVSGMER_ GTQEVAPPT(0.014)PLT(0.109)PT(0.384)S(0.384)HT(0.085)ANT(0.012)S(0.012)PRPVSGMER GT(-51.96)QEVAPPT(-14.35)PLT(-5.49)PT(0)S(0)HT(-6.57)ANT(-15.18)S(-15.18)PRPVS(-30.06)GMER 14 3 1066.1746 0.28781 0 0 0 0 0 0 0 0 2997 586 355 355 2504;2505;3694;3695 2844;2845;2846;2847;2848;4165;4166;4167 23584 14674 Mix4_TiO2_Reinj_1_4 5195 34800 21596 Mix4_TiO2_Reinj_1_4 4587 P48730;P48730-2 P48730 P48730 >sp|P48730|KC1D_HUMAN Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D PE=1 SV=2;>sp|P48730-2|KC1D_HUMAN Isoform 2 of Casein kinase I isoform delta OS=Homo sapiens GN=CSNK1D 0.472753 0 0.425368 -0.359742 1.90689 17.926 0.0333654 -12.7211 0.907724 42.156 0.472753 0 4.82887E-45 200.14 0.273673 0 0.0365223 63.425 0.452878 0 1.04861 39.205 1 T TSHTANTSPRPVS 4.82887E-45 200.14 _GTQEVAPPTPLTPTSHTANpTSPRPVSGMER_ GTQEVAPPT(0.001)PLT(0.01)PT(0.004)S(0.004)HT(0.01)ANT(0.473)S(0.473)PRPVS(0.027)GMER GT(-63.38)QEVAPPT(-26.82)PLT(-16.91)PT(-20.9)S(-20.9)HT(-16.91)ANT(0)S(0)PRPVS(-12.5)GMER 20 3 1066.1746 0.55293 0 0 0 0 0 0 0 0 2998 590 15 15 4962;5028 5643;5719 47892 29285 Mix4_InSol_TiO2_2 2347 47893 29286 Mix4_InSol_Tio2_Reinj_1 3268 P49207 P49207 P49207 >sp|P49207|RL34_HUMAN 60S ribosomal protein L34 OS=Homo sapiens GN=RPL34 PE=1 SV=3 0.431795 3.57893 0 0 0 0 0 0 0.431795 3.57893 0.00491623 66.695 0.163024 -4.96109 0.00389839 123.37 1 T RRLSYNTASNKTR CK1 0.081 0.00389839 123.37 _RLSYNpTASNK_ RLS(0.189)Y(0.189)NT(0.432)AS(0.189)NK RLS(-3.58)Y(-3.58)NT(3.58)AS(-3.58)NK 6 2 617.28481 -0.012376 0 0 0 0 0 0 0 0 2999 592 2204 2204 110;111 128;129 1129 720 Mix4_TiO2_Reinj_1_1 3630 1132 721 Mix4_TiO2_1_1 5072 P49327 P49327 P49327 >sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens GN=FASN PE=1 SV=3 1 96.68 1 77.6695 9.95051E-26 159.36 0 0 1 96.68 2.01643E-18 150.9 0 0 0 0 0 0 1 T SELACPTPKEDGL CDK1;CK2;Proline-directed 0.0057 9.95051E-26 159.36 _ADEASELACPpTPK_ ADEASELACPT(1)PK ADEAS(-96.68)ELACPT(96.68)PK 11 2 734.80491 0.82198 910520 179870 0 0 730640 0 0 0 3000 596 394 394 2103;2104 2381;2383 19267 11697 Mix4_InSol_Tio2_Reinj_1 4596 19252 11688 Mix4_TiO2_1_4 3537 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.71027 8.8878 0.00609953 -19.0805 2.9786E-11 158.36 4.38529E-06 -53.3476 6.81167E-09 145.68 0.235744 -1.3314 1.6136E-06 120.52 0.71027 8.8878 0.000141709 105.97 1 T VSSSDLTGRQEVS CK1 0.081 2.9786E-11 158.36 _GAPANVSSSDLpTGRQEVSR_ GAPANVS(0.066)S(0.066)S(0.066)DLT(0.71)GRQEVS(0.092)R GAPANVS(-10.32)S(-10.32)S(-10.32)DLT(8.89)GRQEVS(-8.89)R 12 3 670.97953 -0.43031 104540 1.4 0 0 0 0 0 0 104540 3001 596 407 407 2856 3252;3253 27215 17018 Mix4_TiO2_2_4 5066 27214 17016 Mix4_TiO2_1_4 5279 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.94215 13.6032 0.91689 9.92482 4.86776E-07 124.13 0.94215 13.6032 0.752415 17.5 0.739576 4.4332 0.00198281 85.997 1 T RIPASQTSVPFDH 0.00226047 84.114 _IPASQpTSVPFDHLGK_ IPAS(0.017)QT(0.942)S(0.041)VPFDHLGK IPAS(-17.5)QT(13.6)S(-13.6)VPFDHLGK 6 2 838.90582 -0.51612 16401 0 16401 0 0 0 0 0 3002 596 362 362 2883 3285 27614 17239 Mix4_TiO2_Reinj_1_1 1862 27608 17224 Mix4_TiO2_1_4 1657 P49674 P49674 P49674 >sp|P49674|KC1E_HUMAN Casein kinase I isoform epsilon OS=Homo sapiens GN=CSNK1E PE=1 SV=1 0.961438 13.9676 0.853868 7.66645 0.00193218 75.897 0.188073 -6.3519 0.125114 35.991 0.961438 13.9676 0.00488813 66.781 0.5 0 0.749635 2.028 0.916269 10.3914 0.00193217 75.897 0.655418 2.79226 0.0115058 58.747 1 T IQPAGNTSPRAIS 0.00193218 75.897 _IQPAGNpTSPR_ IQPAGNT(0.961)S(0.039)PR IQPAGNT(13.97)S(-13.97)PR 7 2 560.76097 -0.29698 3570400 550530 0 0 69042 14084 317330 2619400 3003 600 138 138 6201 7083 61462 37256 Mix4_TiO2_1_4 5448 61462 37256 Mix4_TiO2_1_4 5448 P49759 P49759 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2 0.547368 0.825333 0.547368 0.825333 0.000303672 89.752 0 0 0 0 0.202177 -5.88944 1.46127 21.171 1 T SHRRKRTRSVEDD CAMK2;PKA 0.004788 0.000303672 89.752 _pTRSVEDDEEGHLICQSGDVLSAR_ T(0.547)RS(0.453)VEDDEEGHLICQSGDVLSAR T(0.83)RS(-0.83)VEDDEEGHLICQS(-85.44)GDVLS(-89.75)AR 1 3 885.05684 -0.39846 101930 101930 0 0 0 0 0 0 3004 600;1624 330;328 330 6649 7612;7613 67444 41436 Mix4_TiO2_1_5 4943 67443 41435 Mix4_TiO2_1_4 5002 P49759;Q9HAZ1 P49759;Q9HAZ1 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2;>sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.39811 0 0.39811 0 2.25458E-32 184.37 5.50578E-05 -40.2974 0.0298721 58.973 0.0155142 -15.9726 0.210008 41.002 0.15576 0 0.69416 31.087 0.0565698 -6.85477 8.61479E-07 101.09 0.0551708 -9.18764 0.0838124 53.592 1 T VDFGSATYDDEHH CK2;FHA1 Rad53p 0.059 2.25458E-32 184.37 _VVDFGSApTYDDEHHSTLVSTR_ VVDFGS(0.005)AT(0.398)Y(0.398)DDEHHS(0.017)T(0.08)LVS(0.08)T(0.021)R VVDFGS(-19)AT(0)Y(0)DDEHHS(-13.61)T(-6.95)LVS(-6.95)T(-12.81)R 8 3 806.01994 0.29274 0 0 0 0 0 0 0 0 3005 600;1624 338;336 338 6649 7612;7613 67440 41429 Mix4_TiO2_1_3 4965 67443 41435 Mix4_TiO2_1_4 5002 P49759;Q9HAZ1 P49759;Q9HAZ1 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2;>sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.607676 7.71517 0.607676 7.71517 2.25458E-32 184.37 0.146682 -6.04182 0.0298721 58.973 0.488457 1.14516 2.19665E-16 137.65 0.309829 0 0.69416 31.087 0.363368 0.807639 8.61479E-07 101.09 0.457586 0.689305 0.0838124 53.592 1 T DDEHHSTLVSTRH FHA KAPP 0.155 2.25458E-32 184.37 _VVDFGSATYDDEHHSpTLVSTR_ VVDFGS(0.018)AT(0.103)Y(0.103)DDEHHS(0.083)T(0.608)LVS(0.083)T(0.002)R VVDFGS(-15.25)AT(-7.72)Y(-7.72)DDEHHS(-8.64)T(7.72)LVS(-8.64)T(-24.22)R 16 3 806.01994 0.22899 4329100 4329100 0 0 0 0 0 0 3006 600;1624 342;340 342 6649 7612;7613 67443 41435 Mix4_TiO2_1_4 5002 67443 41435 Mix4_TiO2_1_4 5002 P49759;Q9HAZ1 P49759;Q9HAZ1 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2;>sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.916336 10.3954 0.916336 10.3954 2.25458E-32 184.37 0.498424 0 0.0298721 58.973 0.91262 10.1888 2.19665E-16 137.65 0.309829 0 0.69416 31.087 0.829177 6.86279 8.61479E-07 101.09 0.827478 6.83324 0.0838124 53.592 1 T HSTLVSTRHYRAP NEK6 0.076 2.25458E-32 184.37 _VVDFGSATYDDEHHSTLVSpTR_ VVDFGSATYDDEHHSTLVS(0.084)T(0.916)R VVDFGS(-146.9)AT(-172.07)Y(-165.11)DDEHHS(-70.96)T(-53.04)LVS(-10.4)T(10.4)R 20 2 1208.5263 0.23673 2137700 456410 0 0 1373800 0 197570 109930 3007 602 217 217 4833 5486 46132 28204 Mix4_TiO2_1_4 1556 46134 28214 Mix4_TiO2_Reinj_1_3 1683 P49761;P49761-1;P49761-3;P49761-2 P49761 P49761 >sp|P49761|CLK3_HUMAN Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3 PE=1 SV=3;>sp|P49761-1|CLK3_HUMAN Isoform Long of Dual specificity protein kinase CLK3 OS=Homo sapiens GN=CLK3;>sp|P49761-3|CLK3_HUMAN Isoform 3 of Dual specificity protein 0.999876 39.4402 0.999876 39.4402 0.0405206 91.105 0 0 0.994951 22.9621 0.0136577 105.63 0 0 0 0 1 T ERRDSDTYRCEER 0.0136577 105.63 _RDSDpTYR_ RDSDT(1)YR RDS(-39.44)DT(39.44)Y(-49.73)R 5 2 496.6953 0.60215 2420000 68.73 91069 0 0 2328900 0 0 0 3008 606 2504 2504 1795 2026 16522 9964 Mix4_TiO2_Reinj_1_1 5268 16522 9964 Mix4_TiO2_Reinj_1_1 5268 P49792 P49792 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS=Homo sapiens GN=RANBP2 PE=1 SV=2 0.96303 14.5789 0.96303 14.5789 0.0255519 66.831 1 T SSTSETTPKAVVS CDK1;CK1;FHA KAPP;Proline-directed 0.0057 0.0255519 66.831 _ERTDVIQGDDVADATSEVEVSSTSETpTPK_ ERTDVIQGDDVADATSEVEVSST(0.001)S(0.003)ET(0.034)T(0.963)PK ERT(-66.83)DVIQGDDVADAT(-66.83)S(-65.77)EVEVS(-42.56)S(-37.23)T(-31.65)S(-25.82)ET(-14.58)T(14.58)PK 27 3 1049.4681 -1.5003 144170 0 0 0 144170 0 0 0 3009 609 19 19 473;6241 537;7130 4440 2675 Mix4_InSol_TiO2_1 3958 61901 37507 Mix4_TiO2_1_4 3231 P49840 P49840 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2 0.705777 5.43096 0.386111 1.56674 4.20028E-27 158.45 0.403058 -0.858513 1.57093E-05 98.08 0.363914 -0.787337 1.26802E-19 152.38 0 0 0.705777 5.43096 2.29096E-19 148.91 0.333333 0 3.08254E-19 146.23 1 T GSGRARTSSFAEP CAMK2 0.042 4.20028E-27 158.45 _ARpTSSFAEPGGGGGGGGGGPGGSASGPGGTGGGK_ ART(0.706)S(0.202)S(0.092)FAEPGGGGGGGGGGPGGSASGPGGTGGGK ART(5.43)S(-5.43)S(-8.84)FAEPGGGGGGGGGGPGGS(-109.12)AS(-116.7)GPGGT(-116.7)GGGK 3 3 914.06175 -0.21649 1449700 0.096854 0 0 0 0 0 1449700 0 3010 610 403 403 2868;2869 3266;3268 27311 17063 Mix4_InSol_TiO2_1 3544 27315 17068 Mix4_TiO2_Reinj_1_4 3234 P49841-2;P49841 P49841-2 P49841-2 >sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 0.985659 18.4428 0.967149 15.0212 5.33725E-24 163.83 0 0 0.983753 17.8995 8.6388E-33 187.8 0.985659 18.4428 8.15592E-17 144.73 0.865602 8.09158 3.80187E-17 151.08 1 T IQAAASTPTNATA Polo box;Proline-directed 0.00405 8.6388E-33 187.8 _IQAAASpTPTNATAASDANTGDR_ IQAAAS(0.014)T(0.986)PTNATAASDANTGDR IQAAAS(-18.44)T(18.44)PT(-36.29)NAT(-58.16)AAS(-121.67)DANT(-144.73)GDR 7 2 1092.4819 0.76294 3449200 0.065312 1016800 0 0 2157200 0 159580 115610 3011 610 405 405 2868;2869 3266;3268 27378 17086 Mix4_InSol_TiO2_1 3768 27315 17068 Mix4_TiO2_Reinj_1_4 3234 P49841-2;P49841 P49841-2 P49841-2 >sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 0.709785 7.45021 0.0659263 -8.50233 5.33725E-24 163.83 0 0 0.000287776 -35.3383 8.6388E-33 187.8 0.709785 7.45021 8.15592E-17 144.73 0.0828147 -7.43049 3.80187E-17 151.08 1 T AAASTPTNATAAS CK1 0.081 8.6388E-33 187.8 _IQAAASTPpTNATAASDANTGDRGQTNNAASASASNST_ IQAAAS(0.128)T(0.128)PT(0.71)NAT(0.033)AAS(0.001)DANT(0.001)GDRGQTNNAASASASNST IQAAAS(-7.45)T(-7.45)PT(7.45)NAT(-13.29)AAS(-30.44)DANT(-29.81)GDRGQT(-34.97)NNAAS(-52.11)AS(-59.33)AS(-65.47)NS(-65.47)T(-65.47) 9 3 1182.5173 -0.3327 507670 0.009613 0 0 0 0 0 507670 0 3012 610 7 7 6265 7156;7157 62429 37978 Mix4_InSol_Tio2_Reinj_2 4459 62407 37966 Mix4_InSol_Tio2_Reinj_1 5286 P49841-2;P49841 P49841-2 P49841-2 >sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 0.568008 4.91724 0.283832 -1.00924 0.000520744 80.788 0.28708 -0.940067 0.002624 77.115 0.458119 -0.547658 0.000233994 90.75 0.568008 4.91724 2.55026E-05 97.975 1 T MSGRPRTTSFAES CAMK2 0.042 2.55026E-05 97.975 _pTTSFAESCKPVQQPSAFGSMK_ T(0.568)T(0.183)S(0.062)FAES(0.062)CKPVQQPS(0.062)AFGS(0.062)MK T(4.92)T(-4.92)S(-9.6)FAES(-9.6)CKPVQQPS(-9.6)AFGS(-9.6)MK 1 3 790.01649 -0.16373 160910 0 0 0 0 0 0 160910 3013 610 8 8 6265 7156;7157 62407 37966 Mix4_InSol_Tio2_Reinj_1 5286 62407 37966 Mix4_InSol_Tio2_Reinj_1 5286 P49841-2;P49841 P49841-2 P49841-2 >sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2 0.523355 1.14392 0.358084 0 0.000520744 80.788 0.356459 0 0.002624 77.115 0.51969 0.547658 0.000233994 90.75 0.523355 1.14392 2.55026E-05 97.975 1 T SGRPRTTSFAESC FHA KAPP;PKA 0.042 2.55026E-05 97.975 _TpTSFAESCKPVQQPSAFGSM(ox)K_ T(0.402)T(0.523)S(0.074)FAESCKPVQQPSAFGSMK T(-1.14)T(1.14)S(-8.47)FAES(-60.1)CKPVQQPS(-97.98)AFGS(-97.98)MK 2 3 795.34813 0.023379 1864900 0 0 0 0 0 1113400 751550 3014 612 114 114 2784 3173 26629 16627 Mix4_TiO2_1_4 4476 26629 16627 Mix4_TiO2_1_4 4476 P50479;P50479-2 P50479 P50479 >sp|P50479|PDLI4_HUMAN PDZ and LIM domain protein 4 OS=Homo sapiens GN=PDLIM4 PE=1 SV=2;>sp|P50479-2|PDLI4_HUMAN Isoform 2 of PDZ and LIM domain protein 4 OS=Homo sapiens GN=PDLIM4 0.704076 4.35904 0.704076 4.35904 0.000802068 92.631 0 0 1 T IQDGSPTTSRRPS 0.000802068 92.631 _IHIDPEIQDGSPpTTSR_ IHIDPEIQDGS(0.258)PT(0.704)T(0.032)S(0.006)R IHIDPEIQDGS(-4.36)PT(4.36)T(-13.43)S(-20.74)R 13 2 923.42256 -0.43253 57848 57848 0 0 0 0 0 0 3015 613 755 755 1398 1571 13055 8030 Mix4_TiO2_1_3 8248 13054 8027 Mix4_TiO2_1_3 8154 P50570;P50570-2 P50570 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DNM2 PE=1 SV=2;>sp|P50570-2|DYN2_HUMAN Isoform 2 of Dynamin-2 OS=Homo sapiens GN=DNM2 0.166421 0 0.166421 0 2.04483E-17 138.96 0 0 0.156556 -0.398319 5.33404E-11 119.67 0 0 0 0 1 T PPPVDDTWLQSAS PLK1 0.033462 2.04483E-17 138.96 _EALNIIGDISTSTVSTPVPPPVDDpTWLQSASSHSPTPQR_ EALNIIGDISTSTVST(0.001)PVPPPVDDT(0.166)WLQS(0.166)AS(0.166)S(0.166)HS(0.166)PT(0.166)PQR EALNIIGDIS(-42.95)T(-40.16)S(-34.88)T(-34.88)VS(-30.79)T(-21.41)PVPPPVDDT(0)WLQS(0)AS(0)S(0)HS(0)PT(0)PQR 25 4 1046.0073 -0.028541 0 0 0 0 0 0 0 0 3016 613 766 766 1398 1571 13061 8042 Mix4_TiO2_Reinj_1_5 8549 13054 8027 Mix4_TiO2_1_3 8154 P50570;P50570-2 P50570 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DNM2 PE=1 SV=2;>sp|P50570-2|DYN2_HUMAN Isoform 2 of Dynamin-2 OS=Homo sapiens GN=DNM2 0.66383 6.04616 0.511979 6.47747 2.04483E-17 138.96 0 0 0.66383 6.04616 5.33404E-11 119.67 0 0 0 0 1 T ASSHSPTPQRRPV CDK1;CDK2;Proline-directed 0.0057 2.04483E-17 138.96 _EALNIIGDISTSTVSTPVPPPVDDTWLQSASSHSPpTPQR_ EALNIIGDISTSTVSTPVPPPVDDT(0.043)WLQS(0.043)AS(0.043)S(0.043)HS(0.165)PT(0.664)PQR EALNIIGDIS(-65.24)T(-62.32)S(-62.32)T(-64.09)VS(-53.31)T(-45.54)PVPPPVDDT(-11.91)WLQS(-11.91)AS(-11.91)S(-11.91)HS(-6.05)PT(6.05)PQR 36 4 1046.0073 0.11469 2750600 382340 0 0 2368300 0 0 0 3017 614 170 170 649;5267 747;5995 6226 3679 Mix4_TiO2_1_4 2522 6211 3634 Mix4_InSol_TiO2_1 3259 P50613 P50613 P50613 >sp|P50613|CDK7_HUMAN Cell division protein kinase 7 OS=Homo sapiens GN=CDK7 PE=1 SV=1 1 80.6565 1 80.6565 0.00374896 121.96 1 73.5169 0.00456835 118.35 1 65.2331 0.00434361 115.7 0.99993 44.5398 0.0579388 44.54 1 81.6719 0.00141382 132.25 1 68.4882 0.00440604 119.06 1 T SPNRAYTHQVVTR CAMK2 0.042 0.00141382 132.25 _AYpTHQVVTR_ AYT(1)HQVVTR AY(-80.66)T(80.66)HQVVT(-117.46)R 3 2 577.77134 -0.68017 75053000 10023000 5266000 0 54113000 60261 3373300 2216800 3018 617 54 54 3620 4080 34055 21022 Mix4_TiO2_1_4 5303 34057 21024 Mix4_TiO2_Reinj_1_4 5878 P50750-2 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 0.310075 0 0.310075 0 5.35417E-13 137.36 0.123331 -7.66859 1.89478E-24 161.44 0 0 0 0 1 T PPGLSGTTSPRGP NEK6 0.076 1.89478E-24 161.44 _LPAPPIGAAASSGGGGGGGSGGGGGGASAAPAPPGLpSGTTSPR_ LPAPPIGAAASSGGGGGGGSGGGGGGASAAPAPPGLS(0.31)GT(0.31)T(0.07)S(0.31)PR LPAPPIGAAAS(-130.41)S(-130.41)GGGGGGGS(-107.8)GGGGGGAS(-63.94)AAPAPPGLS(0)GT(0)T(-6.48)S(0)PR 39 4 870.41413 0.081062 0 0 0 0 0 0 0 0 3019 617 303 303 4321 4914 41031 25234 Mix4_TiO2_1_4 1460 41031 25234 Mix4_TiO2_1_4 1460 P50750-2;P50750 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9;>sp|P50750|CDK9_HUMAN Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 PE=1 SV=3 0.971356 15.3034 0.971356 15.3034 0.00482119 66.988 0 0 0.89831 9.52778 0.00498774 66.474 0 0 0.954915 14.5643 0.204259 29.433 0.967078 16.5006 0.352039 19.333 1 T SQPNRYTNRVVTL PKA 0.042 0.00482119 66.988 _NSQPNRYpTNR_ NSQPNRY(0.029)T(0.971)NR NS(-66.99)QPNRY(-15.3)T(15.3)NR 8 2 665.28841 -1.0915 8598000 1480100 0 0 3992800 0 1391100 1733900 3020 624 1423 1423 1186 1333 11152 6829 Mix4_InSol_Tio2_Reinj_1 1965 11152 6829 Mix4_InSol_Tio2_Reinj_1 1965 P51532 P51532 P51532 >sp|P51532|SMCA4_HUMAN Transcription activator BRG1 OS=Homo sapiens GN=SMARCA4 PE=1 SV=2 0.998895 29.6092 0 0 0.92184 10.9547 8.20612E-07 128.86 0.883743 8.86347 8.04335E-05 111.28 0.998895 29.6092 4.38512E-09 149.61 1 T SDAGSSTPTTSTR Polo box;Proline-directed 0.00405 4.38512E-09 149.61 _DSDAGSSpTPTTSTR_ DSDAGSS(0.001)T(0.999)PTTSTR DS(-110.17)DAGS(-68.43)S(-29.61)T(29.61)PT(-49.38)T(-78.59)S(-94.67)T(-110.23)R 8 2 731.78831 -0.32852 94663 0 0 0 32805 0 32727 29131 3021 631;966 577;573 577 170;171 198;199 1860 1250 Mix4_InSol_TiO2_1 8542 1860 1250 Mix4_InSol_TiO2_1 8542 P51812;Q15418 P51812;Q15418 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1;>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.993202 22.461 0.987763 21.933 0.216378 42.672 0 0 0.993202 22.461 0.00118647 78.951 0.356821 -2.17337 0.213867 44.635 1 T ENGLLMTPCYTAN NEK6;Proline-directed 0.05 0.00118647 78.951 _AENGLLMpTPCYTANFVAPEVLKR_ AENGLLMT(0.993)PCY(0.006)T(0.001)ANFVAPEVLKR AENGLLMT(22.46)PCY(-22.46)T(-29.32)ANFVAPEVLKR 8 3 892.09714 -0.033092 259240 28457 0 0 0 0 230780 0 3022 631;966 581;577 581 170;171 198;199 1861 1251 Mix4_InSol_Tio2_Reinj_1 8517 1860 1250 Mix4_InSol_TiO2_1 8542 P51812;Q15418 P51812;Q15418 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1;>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.588556 2.17337 0.00590789 -22.2322 0.216378 42.672 0 0 0.00116267 -29.3158 0.00118647 78.951 0.588556 2.17337 0.213867 44.635 1 T LMTPCYTANFVAP 0.00118647 78.951 _AENGLLMTPCYpTANFVAPEVLKR_ AENGLLMT(0.357)PCY(0.055)T(0.589)ANFVAPEVLKR AENGLLMT(-2.17)PCY(-10.32)T(2.17)ANFVAPEVLKR 12 3 892.09714 -0.65675 241600 0 0 0 0 0 0 241600 3023 631;966;1767 231;225;236 231 644;2980 740;741;3389;3390 6175 3618 Mix4_TiO2_1_5 7114 6177 3622 Mix4_TiO2_Reinj_1_3 8007 P51812;Q15418;Q9UK32 P51812;Q15418;Q9UK32 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1;>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2;>sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Ho 0.499919 0 0.499919 0 3.93447E-26 189.68 0 0 0.416083 1.5386 1.73198E-39 232.03 0 0 0.193837 -3.17369 1.28114E-25 177.1 0.444791 -0.945215 1.16935E-25 178.7 1 T AYSFCGTVEYMAP 1.73198E-39 232.03 _AYpSFCGTVEYMAPEVVNR_ AYS(0.5)FCGT(0.5)VEYMAPEVVNR AY(-35.08)S(0)FCGT(0)VEY(-48.46)MAPEVVNR 7 3 724.97585 -0.072829 27718 27718 0 0 0 0 0 0 3024 631 365 365 6141 7010;7011;7012 60752 36773 Mix4_InSol_Tio2_Reinj_2 4445 60763 36827 Mix4_TiO2_Reinj_1_3 5449 P51812 P51812 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1 0.824811 7.66759 1 64.9513 1.91635E-06 109.59 0 0 0.99997 44.4112 0.011847 68.866 0.807018 8.0842 7.90244E-05 97.55 0.824811 7.66759 0.000646008 87.865 1 T PEFTAKTPKDSPG CDK1;CK2;FHA1 Rad53p;Proline-directed 0.0057 8.5638E-16 148.64 _pTPKDSPGIPPSANAHQLFR_ T(0.825)PKDS(0.141)PGIPPS(0.034)ANAHQLFR T(7.67)PKDS(-7.67)PGIPPS(-13.84)ANAHQLFR 1 3 705.01239 -0.063649 510940 0 0 0 0 0 370250 140680 3025 633 315 315 2573;3213;5391 2926;2927;3645;6134;6136 52465 32098 Mix4_TiO2_Reinj_1_4 7662 24128 14982 Mix4_TiO2_Reinj_1_2 7017 P51946 P51946 P51946 >sp|P51946|CCNH_HUMAN Cyclin-H OS=Homo sapiens GN=CCNH PE=1 SV=1 1 75.6422 1 80.364 2.47448E-13 153.85 0 0 1 75.6422 2.45412E-16 187.36 0 0 0.999999 61.3255 2.50612E-09 130.54 1 70.2382 7.41762E-06 104.06 1 T HEEEEWTDDDLVE CK2;FHA1 Rad53p 0.059 2.45412E-16 187.36 _SKHEEEEWpTDDDLVESL_ SKHEEEEWT(1)DDDLVESL S(-75.64)KHEEEEWT(75.64)DDDLVES(-154.38)L 9 2 1070.9334 0.75547 27523000 49.373 3090500 0 0 23918000 0 307910 206750 3026 634 51 51 2097;2098 2374;2375 19188 11661 Mix4_TiO2_Reinj_1_2 2408 19180 11653 Mix4_TiO2_Reinj_1_2 2789 P51948 P51948 P51948 >sp|P51948|MAT1_HUMAN CDK-activating kinase assembly factor MAT1 OS=Homo sapiens GN=MNAT1 PE=1 SV=1 1 2.90858 1 57.0331 0.0372595 57.033 1 2.90858 0.000241509 111.54 1 33.3435 0.256847 33.344 1 2.22494 0.0028488 82.956 1 T NCPECGTPLRKSN CDK1;CDK2;Proline-directed 0.0057 0.000241509 111.54 _GAGNCPECGpTPLRK_ GAGNCPECGT(1)PLRK GAGNCPECGT(2.91)PLRK 10 3 532.89346 -0.35837 951320 65860 0 0 587440 0 166840 131180 3027 636 479 479 3395;3396 3836;3837 31971 19766 Mix4_TiO2_1_4 7383 31971 19766 Mix4_TiO2_1_4 7383 P51956;P51956-2 P51956 P51956 >sp|P51956|NEK3_HUMAN Serine/threonine-protein kinase Nek3 OS=Homo sapiens GN=NEK3 PE=1 SV=2;>sp|P51956-2|NEK3_HUMAN Isoform 2 of Serine/threonine-protein kinase Nek3 OS=Homo sapiens GN=NEK3 1 111.612 1 111.612 1.33869E-07 111.61 1 65.8934 0.00401414 76.946 1 T GLDEEDTDFEEED CK2 0.117 1.33869E-07 111.61 _LEPGLDEEDpTDFEEEDDNPDWVSELK_ LEPGLDEEDT(1)DFEEEDDNPDWVSELK LEPGLDEEDT(111.61)DFEEEDDNPDWVS(-111.61)ELK 10 3 1049.0905 0.37249 2326400 715720 0 0 1610600 0 0 0 3028 640 61 61 4380 4981 41556 25542 Mix4_InSol_Tio2_Reinj_1 5837 41557 25544 Mix4_TiO2_1_4 4856 P52292 P52292 P52292 >sp|P52292|IMA2_HUMAN Importin subunit alpha-2 OS=Homo sapiens GN=KPNA2 PE=1 SV=1 0.522734 0.395202 0.00280381 -25.5103 1.60416E-33 215.07 0 0 0.142342 -7.79982 1.96114E-20 186.22 0.139988 -7.88414 3.16664E-06 112.12 0.522734 0.395202 0.0210302 63.229 1 T SFPDDATSPLQEN FHA2 Rad53p 0.114 1.60416E-33 215.07 _NVSSFPDDApTSPLQENR_ NVSSFPDDAT(0.523)S(0.477)PLQENR NVS(-63.23)S(-63.23)FPDDAT(0.4)S(-0.4)PLQENR 10 2 978.92038 0.15981 60189 0.29676 0 0 0 0 0 0 60189 3029 641 25 25 1386 1558 12952 7984 Mix4_TiO2_1_4 3956 12949 7981 Mix4_InSol_TiO2_1 4900 P52564 P52564 P52564 >sp|P52564|MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens GN=MAP2K6 PE=1 SV=1 0.634127 6.11613 0.634127 6.11613 0.214582 40.007 0 0 0.00233848 -25.6309 0.0140827 66.639 0.00471992 -18.9044 0.00756307 73.135 0.0677525 -6.61442 0.396345 35.287 1 T AFEQPQTSSTPPR 0.00756307 73.135 _EAFEQPQpTSSTPPRDLDSK_ EAFEQPQT(0.634)S(0.155)S(0.155)T(0.041)PPRDLDS(0.015)K EAFEQPQT(6.12)S(-6.12)S(-6.12)T(-11.91)PPRDLDS(-16.3)K 8 2 1106.9915 0.54203 42119 42119 0 0 0 0 0 0 3030 641 28 28 1386 1558 12953 7985 Mix4_TiO2_Reinj_1_4 4485 12949 7981 Mix4_InSol_TiO2_1 4900 P52564 P52564 P52564 >sp|P52564|MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens GN=MAP2K6 PE=1 SV=1 0.855107 8.85072 0.47437 3.09899 0.214582 40.007 0 0 0.855107 8.85072 0.0140827 66.639 0.366752 0 0.00756307 73.135 0.310719 0 0.396345 35.287 1 T QPQTSSTPPRDLD CDK1;CDK2;Polo box;Proline-directed 0.00405 0.00756307 73.135 _EAFEQPQTSSpTPPRDLDSK_ EAFEQPQT(0.002)S(0.016)S(0.111)T(0.855)PPRDLDS(0.016)K EAFEQPQT(-25.63)S(-17.4)S(-8.85)T(8.85)PPRDLDS(-17.4)K 11 3 738.33012 -0.16872 634380 0 0 0 634380 0 0 0 3031 649 1022 1022 133 154 1330 831 Mix4_TiO2_1_5 2687 1331 832 Mix4_TiO2_Reinj_1_5 2957 P52948;P52948-5;P52948-2;P52948-6 P52948 P52948 >sp|P52948|NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98 PE=1 SV=4;>sp|P52948-5|NUP98_HUMAN Isoform ADIR2 of Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens GN=NUP98;>sp|P52948-2|NUP98_HUMAN Isoform Nup98-Nup96 prec 0.589691 1.67732 0.589691 1.67732 0.381193 17.91 0.0582824 -12.0795 0.00297179 80.386 1 T LPSKADTSQEICS CK2 0.117 0.00297179 80.386 _ADpTSQEICSPR_ ADT(0.59)S(0.401)QEICS(0.01)PR ADT(1.68)S(-1.68)QEICS(-17.91)PR 3 2 672.2685 0.38537 19618 19618 0 0 0 0 0 0 3032 651 210 210 3095 3518 29421 18346 Mix4_TiO2_1_3 5268 29421 18346 Mix4_TiO2_1_3 5268 P53350 P53350 P53350 >sp|P53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 OS=Homo sapiens GN=PLK1 PE=1 SV=1 0.999999 61.0017 0.999999 61.0017 6.0443E-21 162.97 0 0 0.999997 55.9747 9.70322E-07 115.39 0.924117 10.8868 0.200601 39.888 0.997379 25.8065 0.0150333 67.683 1 T DGERKKTLCGTPN AURORA;AURORA-1;AURORA-A;CAMK2;PKA 0.004788 6.0443E-21 162.97 _KKpTLCGTPNYIAPEVLSK_ KKT(1)LCGTPNYIAPEVLSK KKT(61)LCGT(-61)PNY(-124.72)IAPEVLS(-162.97)K 3 3 700.3584 0.011994 15233000 2519500 0 0 11640000 0 885920 188230 3033 651 214 214 3095 3518 29418 18342 Mix4_InSol_Tio2_Reinj_1 6428 29421 18346 Mix4_TiO2_1_3 5268 P53350 P53350 P53350 >sp|P53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 OS=Homo sapiens GN=PLK1 PE=1 SV=1 0.499255 0 0.0265481 -15.6428 6.0443E-21 162.97 0 0 0.182023 -6.52604 9.70322E-07 115.39 0.129743 -8.26473 0.200601 39.888 0.499255 0 0.0150333 67.683 1 T KKTLCGTPNYIAP NEK6;Proline-directed 0.05 6.0443E-21 162.97 _KKpTLCGTPNYIAPEVLSK_ KKT(0.499)LCGT(0.499)PNY(0.001)IAPEVLSK KKT(0)LCGT(0)PNY(-25.28)IAPEVLS(-47.35)K 7 3 700.3584 -0.44386 0 0 0 0 0 0 0 0 3034 652 453 453 5901;5902;5903 6730;6731;6732 58193 35340 Mix4_InSol_Tio2_Reinj_1 4120 58191 35338 Mix4_InSol_TiO2_1 4153 P53396 P53396 P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens GN=ACLY PE=1 SV=3 0.822199 6.65916 0.446815 -0.918054 0.00954965 73.068 0 0 0.445039 -0.940484 0.00954967 73.068 0.42104 -1.38303 7.31489E-06 104.23 0.822199 6.65916 0.0561844 55.654 1 T TPAPSRTASFSES 7.31489E-06 104.23 _pTASFSESRADEVAPAKK_ T(0.822)AS(0.177)FSESRADEVAPAKK T(6.66)AS(-6.66)FS(-34.49)ES(-41.04)RADEVAPAKK 1 3 625.29457 -0.17406 2366700 0 0 0 0 0 0 2366700 3035 653 3 3 2501;2502 2841;2842 23544 14654 Mix4_TiO2_Reinj_1_4 4534 23542 14652 Mix4_TiO2_1_2 3164 P53611 P53611 P53611 >sp|P53611|PGTB2_HUMAN Geranylgeranyl transferase type-2 subunit beta OS=Homo sapiens GN=RABGGTB PE=1 SV=2 1 15.2126 1 56.9326 0.0169849 56.933 0 0 1 15.2126 0.0409541 48.996 1 25.312 0.723641 30.485 1 13.2027 0.668935 31.603 1 T ____MGTPQKDVI CDK1;CDK2;Proline-directed 0.0057 0.0169849 56.933 _(ac)GpTPQKDVIIK_ GT(1)PQKDVIIK GT(15.21)PQKDVIIK 2 2 610.81795 0.33457 1488900 234080 0 0 940860 0 169000 145010 3036 664 505 505 5703 6497 55919 34228 Mix4_TiO2_1_3 6641 55920 34229 Mix4_TiO2_Reinj_1_3 7377 P54646 P54646 P54646 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2 0.113885 0 0.113885 0 0.0287076 71.628 0.0856808 -6.97623 0.000365423 81.326 1 T RSSFDSTTAESHS CK2 0.117 0.000365423 81.326 _pSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPR_ S(0.114)S(0.114)FDS(0.114)T(0.114)T(0.098)AES(0.106)HS(0.106)LS(0.106)GS(0.106)LT(0.021)GS(0.001)LTGSTLSSVSPR S(0)S(0)FDS(0)T(0)T(-0.64)AES(-0.31)HS(-0.31)LS(-0.31)GS(-0.31)LT(-7.32)GS(-22.98)LT(-44.18)GS(-56.05)T(-61.26)LS(-69.53)S(-71.63)VS(-71.63)PR 6 3 1075.1595 0.098225 0 0 0 0 0 0 0 0 3037 664;843 172;198 198 6210 7094 61563 37311 Mix4_TiO2_1_4 4704 61563 37311 Mix4_TiO2_1_4 4704 P54646;Q13131-2;Q13131 P54646;Q13131-2 Q13131-2 >sp|P54646|AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2;>sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_ 0.852822 7.63015 0.852822 7.63015 1.46771E-12 140.03 0 0 0.183552 -5.05346 0.459606 31.17 1 T DGEFLRTSCGSPN 1.46771E-12 140.03 _pTSCGSPNYAAPEVISGR_ T(0.853)S(0.147)CGSPNYAAPEVISGR T(7.63)S(-7.63)CGS(-82.11)PNY(-132.56)AAPEVIS(-140.03)GR 1 2 923.39549 0.064312 47301 47301 0 0 0 0 0 0 3038 665 773 773 2008;2009 2274;2276;2277 18412 11183 Mix4_TiO2_Reinj_1_5 5928 18409 11179 Mix4_TiO2_Reinj_1_5 5189 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.467881 1.69625 6.87049E-05 -41.0403 1.37452E-38 219.69 2.00662E-05 -46.9064 3.51501E-10 129.8 0.467881 1.69625 4.16059E-48 247.82 0 0 0.137201 -4.90197 9.58262E-17 142.64 0.0448404 -10.6566 0.000151466 97.062 1 T ENSSDPTYTSSLG CK1;FHA KAPP;PLK1 0.033462 4.16059E-48 247.82 _FLEENSSDPpTYTSSLGGK_ FLEENS(0.215)S(0.317)DPT(0.468)YTSSLGGK FLEENS(-3.37)S(-1.7)DPT(1.7)Y(-46.01)T(-37.08)S(-67.88)S(-80.7)LGGK 10 2 1006.4303 0.55817 0 0 0 0 0 0 0 0 0 3039 665 976 976 4420;5604 5029;6387 54800 33555 Mix4_InSol_Tio2_Reinj_1 4100 54804 33560 Mix4_TiO2_1_5 3252 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.999856 38.602 0.972136 15.4269 5.48205E-10 125.53 0.965352 14.4501 0.000741396 89.869 0.999175 33.8396 2.25322E-06 111.77 0 0 0.822539 6.86595 0.000456267 93.346 0.999856 38.602 4.69075E-06 104.93 1 T SQAKPGTPGGTGG ERK/MAPK;Proline-directed 0.0025 5.48205E-10 125.53 _SQAKPGpTPGGTGGPAPQY_ SQAKPGT(1)PGGTGGPAPQY S(-52.02)QAKPGT(38.6)PGGT(-38.6)GGPAPQY(-104.93) 7 2 875.89344 0.44943 4626200 1018100 50975 0 2603900 0 11305 942000 3040 665 980 980 4420;5604 5029;6387 54796 33550 Mix4_InSol_TiO2_1 4198 54804 33560 Mix4_TiO2_1_5 3252 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.998747 29.0137 0.259142 -4.55371 5.48205E-10 125.53 0.0346482 -14.4501 0.000741396 89.869 0.724774 4.20513 2.25322E-06 111.77 0 0 0.998747 29.0137 0.000456267 93.346 0.0995207 -8.48076 4.69075E-06 104.93 1 T PGTPGGTGGPAPQ 5.48205E-10 125.53 _SQAKPGTPGGpTGGPAPQY_ SQAKPGT(0.001)PGGT(0.999)GGPAPQY S(-74.24)QAKPGT(-29.01)PGGT(29.01)GGPAPQY(-76.28) 11 2 875.89344 0.35786 1697400 0 0 0 600810 0 1096600 0 3041 670 267 267 5410 6157 52743 32232 Mix4_TiO2_Reinj_1_3 7880 52743 32232 Mix4_TiO2_Reinj_1_3 7880 P55081 P55081 P55081 >sp|P55081|MFAP1_HUMAN Microfibrillar-associated protein 1 OS=Homo sapiens GN=MFAP1 PE=1 SV=2 1 109.788 0.999996 53.8621 4.13193E-17 138.89 1 109.788 1.63568E-46 215.91 1 T ALDALNTDDENDE CK2 0.117 1.63568E-46 215.91 _SLAALDALNpTDDENDEEEYEAWK_ SLAALDALNT(1)DDENDEEEYEAWK S(-120.27)LAALDALNT(109.79)DDENDEEEY(-109.79)EAWK 10 3 907.70776 0.14054 418450 144790 0 0 273670 0 0 0 3042 689 5 5 4415;4416 5023;5024 42049 25919 Mix4_InSol_Tio2_Reinj_2 2688 42002 25900 Mix4_InSol_TiO2_1 2987 P60468 P60468 P60468 >sp|P60468|SC61B_HUMAN Protein transport protein Sec61 subunit beta OS=Homo sapiens GN=SEC61B PE=1 SV=2 0.599506 6.96267 0.100472 -4.86409 1.19343 14.077 0 0 0.0928787 -6.61885 0.447227 33.943 0.317097 0.733301 2.39429E-06 107.44 0.599506 6.96267 0.000474947 90.763 1 T __MPGPTPSGTNV Proline-directed 0.05 2.39429E-06 107.44 _PGPpTPSGTNVGSSGRSPSKAVAAR_ PGPT(0.6)PS(0.121)GT(0.056)NVGS(0.056)S(0.056)GRS(0.056)PS(0.056)KAVAAR PGPT(6.96)PS(-6.96)GT(-10.3)NVGS(-10.3)S(-10.3)GRS(-10.3)PS(-10.3)KAVAAR 4 2 1159.5661 -0.17632 25448 0 0 0 0 0 0 25448 3043 702 190 190 2041;2042;3023;3024 2314;2315;3437;3438 28834 17943 Mix4_TiO2_1_6 2509 28837 17946 Mix4_TiO2_Reinj_1_6 3023 P62070 P62070 P62070 >sp|P62070|RRAS2_HUMAN Ras-related protein R-Ras2 OS=Homo sapiens GN=RRAS2 PE=1 SV=1 0.789434 5.73928 0.789434 5.73928 0.0115271 71.862 0 0 0.325967 -3.15507 6.66702E-08 135.66 0.0330982 -14.6558 0.27937 35.01 0 0 1 T PPSPEPTRKEKDK CK2 0.117 6.66702E-08 135.66 _KFQEQECPPSPEPpTR_ KFQEQECPPS(0.211)PEPT(0.789)R KFQEQECPPS(-5.74)PEPT(5.74)R 14 2 955.41114 0.37766 34634 34634 0 0 0 0 0 0 3044 704 130 130 2100 2378 19234 11679 Mix4_TiO2_Reinj_1_6 4733 19234 11679 Mix4_TiO2_Reinj_1_6 4733 P62241 P62241 P62241 >sp|P62241|RS8_HUMAN 40S ribosomal protein S8 OS=Homo sapiens GN=RPS8 PE=1 SV=2 1 76.8581 0 0 1 76.8581 0.00625185 76.858 1 T KKGAKLTPEEEEI CK2;Proline-directed 0.05 0.00625185 76.858 _GAKLpTPEEEEILNK_ GAKLT(1)PEEEEILNK GAKLT(76.86)PEEEEILNK 5 3 550.93772 0.036363 22168 0 0 0 22168 0 0 0 3045 741 509 509 6290 7186;7187 62934 38330 Mix4_TiO2_1_5 3138 62934 38330 Mix4_TiO2_1_5 3138 P78362-2;P78362 P78362-2 P78362-2 >sp|P78362-2|SRPK2_HUMAN Isoform 2 of Serine/threonine-protein kinase SRPK2 OS=Homo sapiens GN=SRPK2;>sp|P78362|SRPK2_HUMAN Serine/threonine-protein kinase SRPK2 OS=Homo sapiens GN=SRPK2 PE=1 SV=3 0.883124 8.7942 0.883124 8.7942 0.00619088 80.698 0.132447 -7.40091 0.206731 31.116 0.163719 -7.07582 0.00395855 88.708 0.162582 -7.11259 0.00143801 97.754 2 T TVSASSTGDLPKA FHA2 Rad53p 0.114 0.00619088 80.698 _TVpSASSpTGDLPK_ TVS(1)ASS(0.117)T(0.883)GDLPK T(-38.65)VS(38.65)AS(-34.8)S(-8.79)T(8.79)GDLPK 7 2 661.76747 0.10754 72670 72670 0 0 0 0 0 0 3046 743 1793 1793 4887 5558 46952 28733 Mix4_TiO2_Reinj_1_2 7604 46952 28733 Mix4_TiO2_Reinj_1_2 7604 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.626801 2.25189 0.499988 0 0.104412 49.937 0 0 0.626801 2.25189 0.00376225 76.922 1 T RRGSCVTQVGLLE CK1 0.081 0.00376225 76.922 _RGSCVpTQVGLLESVYEM(ox)FR_ RGS(0.373)CVT(0.627)QVGLLESVYEMFR RGS(-2.25)CVT(2.25)QVGLLES(-75.89)VY(-76.92)EMFR 6 3 776.35684 0.011821 148550 69640 0 0 78914 0 0 0 3047 743 2671 2671 5704 6498 55929 34238 Mix4_TiO2_Reinj_1_2 7338 55927 34236 Mix4_TiO2_Reinj_1_1 8098 P78527;P78527-2 P78527 P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC PE=1 SV=3;>sp|P78527-2|PRKDC_HUMAN Isoform 2 of DNA-dependent protein kinase catalytic subunit OS=Homo sapiens GN=PRKDC 0.230894 0 0.148324 -7.22055 3.06203E-13 134.83 0.122301 -6.048 0.0718279 59.668 0.230894 0 1.25411E-48 214.01 0 0 0 0 1 T DPLVDHTSPSSDS FHA KAPP 0.155 1.25411E-48 214.01 _SSFDWLTGSSTDPLVDHpTSPSSDSLLFAHK_ SSFDWLTGSSTDPLVDHT(0.231)S(0.231)PS(0.181)S(0.231)DS(0.126)LLFAHK S(-108.89)S(-108.75)FDWLT(-83.75)GS(-68.78)S(-57.46)T(-57.46)DPLVDHT(0)S(0)PS(-1.05)S(0)DS(-2.63)LLFAHK 18 3 1105.5012 -0.026069 0 0 0 0 0 0 0 0 0 3048 746 401 401 5126 5831 49595 30289 Mix4_TiO2_Reinj_1_5 7374 49595 30289 Mix4_TiO2_Reinj_1_5 7374 P82094-2;P82094 P82094-2 P82094-2 >sp|P82094-2|TMF1_HUMAN Isoform 2 of TATA element modulatory factor OS=Homo sapiens GN=TMF1;>sp|P82094|TMF1_HUMAN TATA element modulatory factor OS=Homo sapiens GN=TMF1 PE=1 SV=2 0.5 0 0 0 0.5 0 1.57995E-07 103.69 1 T ESGRSATPVNCEQ CAMK2;Proline-directed 0.042 1.57995E-07 103.69 _pSATPVNCEQPDILVSSTPINEGQTVLDK_ S(0.5)AT(0.5)PVNCEQPDILVSSTPINEGQTVLDK S(0)AT(0)PVNCEQPDILVS(-80.51)S(-89.45)T(-89.45)PINEGQT(-103.69)VLDK 3 3 1031.488 0.60031 369090 0 0 0 369090 0 0 0 3049 756 14 14 2760 3145 26134 16153 Mix4_TiO2_1_2 4387 26136 16156 Mix4_TiO2_1_6 4048 Q00535 Q00535 Q00535 >sp|Q00535|CDK5_HUMAN Cell division protein kinase 5 OS=Homo sapiens GN=CDK5 PE=1 SV=3 0.998502 30.0676 0.998502 30.0676 0.00182026 103.55 0.269339 -2.33705 0.233363 27.475 0.108833 -8.56631 0.00146498 100.19 0 0 0.0728382 -10.6926 0.00299627 80.114 0.285015 -1.78569 0.00544742 73.62 1 T EKIGEGTYGTVFK PLK1 0.033462 0.00182026 103.55 _IGEGpTYGTVFK_ IGEGT(0.999)Y(0.001)GT(0.001)VFK IGEGT(30.07)Y(-32.88)GT(-30.07)VFK 5 2 626.28649 0.0012797 21182 21182 0 0 0 0 0 0 3050 756 17 17 2760 3145 26136 16156 Mix4_TiO2_1_6 4048 26136 16156 Mix4_TiO2_1_6 4048 Q00535 Q00535 Q00535 >sp|Q00535|CDK5_HUMAN Cell division protein kinase 5 OS=Homo sapiens GN=CDK5 PE=1 SV=3 0.999984 48.0817 0.999984 48.0817 0.00182026 103.55 0.849294 9.33731 0.233363 27.475 0.999812 37.307 0.00146498 100.19 0 0 0.999983 49.2022 0.00299627 80.114 0.999914 42.8217 0.00544742 73.62 1 T GEGTYGTVFKAKN 0.00182026 103.55 _IGEGTYGpTVFK_ IGEGTYGT(1)VFK IGEGT(-48.08)Y(-69.11)GT(48.08)VFK 8 2 626.28649 -0.1782 1520000 318830 13190 0 989440 0 116870 81703 3051 757 111 111 3075;3076 3496;3497 29306 18286 Mix4_TiO2_Reinj_1_3 2948 29294 18280 Mix4_TiO2_1_4 2509 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.80728 6.22098 0.230408 -5.23763 0.00127469 86.624 0.80728 6.22098 0.0312412 52.994 0.5 0 0.684381 4.9807 0.5 0 0.00127469 86.624 1 T PPRKISTEDINKR FHA2 Rad53p 0.114 0.00127469 86.624 _KISpTEDINKR_ KIS(0.193)T(0.807)EDINKR KIS(-6.22)T(6.22)EDINKR 4 2 642.32139 0.16163 1590200 0 0 0 1311500 0 172080 106590 3052 757 135 135 3768 4253 35652 22038 Mix4_TiO2_1_5 6396 35648 22033 Mix4_TiO2_1_3 6553 Q00536 Q00536 Q00536 >sp|Q00536|CDK16_HUMAN Cell division protein kinase 16 OS=Homo sapiens GN=CDK16 PE=1 SV=1 0.716275 5.4381 0.716275 5.4381 1.59809E-05 116.86 0.584013 1.47343 0.0225677 61.382 0.000824554 -30.8342 0.00155916 90.743 0.31488 -3.36384 0.335659 29.42 0.110984 -9.03647 0.0525665 53.397 1 T GYLEKLTLNSPIF AURORA;AURORA-1;FHA KAPP 0.020748 1.59809E-05 116.86 _LpTLNSPIFDKPLSR_ LT(0.716)LNS(0.205)PIFDKPLS(0.079)R LT(5.44)LNS(-5.44)PIFDKPLS(-9.58)R 2 2 840.93966 -0.086501 244160 61918 182240 0 0 0 0 0 3053 760 394 394 2275 2573 20972 12852 Mix4_TiO2_1_5 4348 20972 12852 Mix4_TiO2_1_5 4348 Q00610;Q00610-2 Q00610 Q00610 >sp|Q00610|CLH1_HUMAN Clathrin heavy chain 1 OS=Homo sapiens GN=CLTC PE=1 SV=5;>sp|Q00610-2|CLH1_HUMAN Isoform 2 of Clathrin heavy chain 1 OS=Homo sapiens GN=CLTC 0.999999 58.3192 0.999999 58.3192 0.0023158 74.714 0.99939 32.142 0.171565 32.142 1 T PKGILRTPDTIRR Proline-directed 0.05 0.0023158 74.714 _GILRpTPDTIR_ GILRT(1)PDTIR GILRT(58.32)PDT(-58.32)IR 5 2 611.32119 0.25159 435500 89743 0 0 345750 0 0 0 3054 767 41 41 4875 5543;5544 46795 28638 Mix4_TiO2_Reinj_1_4 5095 46791 28634 Mix4_TiO2_1_4 4180 Q01196-8;Q01196-2;Q01196-10;Q01196-9;Q01196;Q01196-4;Q01196-3;Q01196-7;Q01196-5;Q01196-6 Q01196-8 Q01196-8 >sp|Q01196-8|RUNX1_HUMAN Isoform AML-1G of Runt-related transcription factor 1 OS=Homo sapiens GN=RUNX1;>sp|Q01196-2|RUNX1_HUMAN Isoform AML-1A of Runt-related transcription factor 1 OS=Homo sapiens GN=RUNX1;>sp|Q01196-10|RUNX1_HUMAN Isoform AML-1I of Runt 0.904439 13.245 0.999719 37.9465 0.0180687 63.674 0.468735 4.22737 0.911609 4.2274 0.904439 13.245 0.251106 31.03 0 0 0 0 1 T STSRRFTPPSTAL CAMK2;FHA KAPP;PKA;Proline-directed 0.004788 0.00428917 81.587 _RFpTPPSTALSPGK_ RFT(0.904)PPS(0.043)T(0.043)ALS(0.01)PGK RFT(13.25)PPS(-13.25)T(-13.25)ALS(-19.62)PGK 3 2 719.85814 0.32838 231130 50699 0 0 180430 0 0 0 3055 768 307 307 5315 6051 51589 31584 Mix4_InSol_TiO2_1 4283 51592 31587 Mix4_TiO2_Reinj_1_4 3830 Q01518;Q01518-2 Q01518 Q01518 >sp|Q01518|CAP1_HUMAN Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 PE=1 SV=5;>sp|Q01518-2|CAP1_HUMAN Isoform 2 of Adenylyl cyclase-associated protein 1 OS=Homo sapiens GN=CAP1 0.498632 0 0.469793 0 4.52763E-10 127.6 0.498632 0 0.133975 45.099 0.400763 0 1.28929 7.8231 1 T SAPKPQTSPSPKR FHA KAPP 0.155 4.52763E-10 127.6 _SGPKPFSAPKPQpTSPSPK_ SGPKPFSAPKPQT(0.499)S(0.499)PS(0.003)PK S(-45.1)GPKPFS(-45.1)APKPQT(0)S(0)PS(-22.66)PK 13 3 639.98719 -0.17348 0 0 0 0 0 0 0 0 3056 773 313 313 5738 6539 56401 34446 Mix4_TiO2_1_4 7436 56401 34446 Mix4_TiO2_1_4 7436 Q01850 Q01850 Q01850 >sp|Q01850|CDR2_HUMAN Cerebellar degeneration-related protein 2 OS=Homo sapiens GN=CDR2 PE=1 SV=2 0.324717 1.59141 0.324717 1.59141 3.01109E-06 112.39 0 0 0.0783764 -6.26574 0.00117625 87.631 1 T KRSSSETILSSLA CK1;FHA KAPP 0.081 3.01109E-06 112.39 _SSSEpTILSSLAGSDIVK_ S(0.225)S(0.225)S(0.225)ET(0.325)ILSSLAGSDIVK S(-1.59)S(-1.59)S(-1.59)ET(1.59)ILS(-65.54)S(-66.62)LAGS(-112.39)DIVK 5 2 887.42952 0.84857 0 0 0 0 0 0 0 0 3057 775 710 710 1320;1500 1489;1684 13901 8463 Mix4_TiO2_Reinj_1_3 9141 13896 8457 Mix4_TiO2_1_3 8415 Q02156 Q02156 Q02156 >sp|Q02156|KPCE_HUMAN Protein kinase C epsilon type OS=Homo sapiens GN=PRKCE PE=1 SV=1 1 156.206 1 101.331 1.73856E-50 261.56 1 66.579 0.0170801 66.579 1 156.206 9.46933E-16 183.79 1 T REEPVLTLVDEAI CK2;FHA1 Rad53p 0.059 1.73856E-50 261.56 _EEPVLpTLVDEAIVK_ EEPVLT(1)LVDEAIVK EEPVLT(156.21)LVDEAIVK 6 3 545.61447 0.060066 4965000 2639700 25918 0 2299400 0 0 0 3058 778 386 386 5036;5151 5728;5865 48684 29767 Mix4_TiO2_Reinj_2_2 3607 49940 30534 Mix4_TiO2_Reinj_1_4 9082 Q02750 Q02750 Q02750 >sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2 0.977771 17.0721 0.810685 7.12288 1.63718E-47 207.85 0.482764 0 1.27964E-05 98.124 0.95319 15.8083 2.09752E-60 229.46 0.977771 17.0721 6.17936E-60 220.97 1 T GLNQPSTPTHAAG ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 2.09752E-60 229.46 _RSDAEEVDFAGWLCSTIGLNQPSpTPTHAAGV_ RSDAEEVDFAGWLCSTIGLNQPS(0.003)T(0.978)PT(0.019)HAAGV RS(-157.37)DAEEVDFAGWLCS(-120.79)T(-120.79)IGLNQPS(-25.07)T(17.07)PT(-17.07)HAAGV 24 3 1122.8414 -0.39107 43355000 1800700 0 0 39401000 2153000 0 0 3059 778 388 388 5036;5151 5728;5865 48688 29771 Mix4_TiO2_2_2 8206 49940 30534 Mix4_TiO2_Reinj_1_4 9082 Q02750 Q02750 Q02750 >sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2 0.482764 0 0.453913 0 1.63718E-47 207.85 0.482764 0 1.27964E-05 98.124 0.161404 -6.22794 2.09752E-60 229.46 0.10776 -9.11311 6.17936E-60 220.97 1 T NQPSTPTHAAGV_ CK1;FHA KAPP 0.081 2.09752E-60 229.46 _RSDAEEVDFAGWLCSTIGLNQPSpTPTHAAGV_ RSDAEEVDFAGWLCSTIGLNQPS(0.034)T(0.483)PT(0.483)HAAGV RS(-58.76)DAEEVDFAGWLCS(-53.15)T(-50.2)IGLNQPS(-11.46)T(0)PT(0)HAAGV 26 3 1122.8414 -0.24218 0 0 0 0 0 0 0 0 3060 782 15 15 5301;6818 6036;7802 69118 42375 Mix4_TiO2_1_6 3950 69124 42382 Mix4_TiO2_Reinj_1_6 5165 Q03135 Q03135 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CAV1 PE=1 SV=4 0.979035 16.6938 0.979035 16.6938 0.00011301 108.46 0 0 0.742558 4.70476 4.38321E-07 132.91 4.57087E-10 -93.3066 2.57439E-06 110.89 1.26767E-06 -58.9655 0.0328815 58.966 1 T SEGHLYTVPIREQ FHA2 Rad53p 0.114 4.38321E-07 132.91 _YVDSEGHLYpTVPIR_ YVDSEGHLY(0.021)T(0.979)VPIR Y(-91.3)VDS(-54.8)EGHLY(-16.69)T(16.69)VPIR 10 2 864.90328 0.12557 286200 58698 0 0 227500 0 0 0 3061 784 14 14 237 272 2352 1504 Mix4_TiO2_2_3 2692 2351 1503 Mix4_TiO2_1_3 3044 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.997707 29.3962 0.990465 23.1757 0.0103589 72.583 0.997707 29.3962 0.227973 29.396 0.833483 10.0047 0.591757 10.005 0.0663773 -11.1612 0.565146 11.161 0 0 1 T RAGGPATPLSPTR ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 0.0103589 72.583 _AGGPApTPLSPTR_ AGGPAT(0.998)PLS(0.001)PT(0.001)R AGGPAT(29.4)PLS(-29.4)PT(-29.4)R 6 2 602.78973 -0.16978 173050 34085 25790 0 113180 0 0 0 3062 784 19 19 237 272 2353 1505 Mix4_TiO2_2_3 2993 2351 1503 Mix4_TiO2_1_3 3044 Q03252 Q03252 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LMNB2 PE=1 SV=3 0.728895 7.30557 0.613963 2.01677 0.0103589 72.583 0.728895 7.30557 0.227973 29.396 0.0832585 -10.0047 0.591757 10.005 0.0663773 -11.1612 0.565146 11.161 0 0 1 T ATPLSPTRLSRLQ FHA KAPP;NEK6 0.076 0.0103589 72.583 _AGGPATPLSPpTR_ AGGPAT(0.136)PLS(0.136)PT(0.729)R AGGPAT(-7.31)PLS(-7.31)PT(7.31)R 11 2 602.78973 0.11734 71510 58609 12901 0 0 0 0 0 3063 792 328 328 3958 4507 37489 23033 Mix4_TiO2_Reinj_1_3 3996 37489 23033 Mix4_TiO2_Reinj_1_3 3996 Q04726;Q04726-4;Q04726-3;Q04726-2 Q04726 Q04726 >sp|Q04726|TLE3_HUMAN Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3 PE=1 SV=2;>sp|Q04726-4|TLE3_HUMAN Isoform 4 of Transducin-like enhancer protein 3 OS=Homo sapiens GN=TLE3;>sp|Q04726-3|TLE3_HUMAN Isoform 3 of Transducin-like enhancer protein 0.694292 3.7423 0.694292 3.7423 4.64142E-19 119.02 1 T PRNDAPTPGTSTT Proline-directed 0.05 4.64142E-19 119.02 _NDAPpTPGTSTTPGLR_ NDAPT(0.694)PGT(0.293)S(0.006)T(0.006)T(0.001)PGLR NDAPT(3.74)PGT(-3.74)S(-20.79)T(-20.79)T(-29.16)PGLR 5 2 782.85378 0.53921 0 0 0 0 0 0 0 0 3064 793 536 536 6123 6989 60483 36572 Mix4_TiO2_1_3 8280 60481 36570 Mix4_TiO2_1_3 8219 Q04759 Q04759 Q04759 >sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens GN=PRKCQ PE=1 SV=3 0.499257 0 0.499257 0 1.90437E-07 116.21 0.441892 -1.01377 2.25198E-05 98.258 1 T MLGDAKTNTFCGT 1.90437E-07 116.21 _pTNTFCGTPDYIAPEILLGQK_ T(0.499)NT(0.499)FCGT(0.001)PDYIAPEILLGQK T(0)NT(0)FCGT(-25.58)PDY(-36.86)IAPEILLGQK 1 2 1159.5424 1.0574 0 0 0 0 0 0 0 0 3065 793 538 538 6123 6989 60481 36570 Mix4_TiO2_1_3 8219 60481 36570 Mix4_TiO2_1_3 8219 Q04759 Q04759 Q04759 >sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens GN=PRKCQ PE=1 SV=3 0.569072 1.20768 0.569072 1.20768 1.90437E-07 116.21 0.558076 1.01377 2.25198E-05 98.258 1 T GDAKTNTFCGTPD 1.90437E-07 116.21 _TNpTFCGTPDYIAPEILLGQK_ T(0.431)NT(0.569)FCGTPDYIAPEILLGQK T(-1.21)NT(1.21)FCGT(-50.74)PDY(-77.79)IAPEILLGQK 3 2 1159.5424 0.21667 2110700 757880 0 0 1352800 0 0 0 3066 793 542 542 6123 6989 60485 36575 Mix4_TiO2_Reinj_1_3 8896 60481 36570 Mix4_TiO2_1_3 8219 Q04759 Q04759 Q04759 >sp|Q04759|KPCT_HUMAN Protein kinase C theta type OS=Homo sapiens GN=PRKCQ PE=1 SV=3 0.733333 7.65822 0.114747 -6.38584 1.90437E-07 116.21 0.733333 7.65822 2.25198E-05 98.258 1 T TNTFCGTPDYIAP Proline-directed 0.05 1.90437E-07 116.21 _TNTFCGpTPDYIAPEILLGQK_ T(0.126)NT(0.126)FCGT(0.733)PDY(0.015)IAPEILLGQK T(-7.66)NT(-7.66)FCGT(7.66)PDY(-16.84)IAPEILLGQK 7 3 773.36399 -0.30916 1079800 0 0 0 1079800 0 0 0 3067 797 776 776 5046 5739;5740 48799 29826 Mix4_TiO2_Reinj_1_3 1656 48799 29826 Mix4_TiO2_Reinj_1_3 1656 Q05193;Q05193-2;Q05193-4;Q05193-3;Q05193-5 Q05193 Q05193 >sp|Q05193|DYN1_HUMAN Dynamin-1 OS=Homo sapiens GN=DNM1 PE=1 SV=2;>sp|Q05193-2|DYN1_HUMAN Isoform 2 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-4|DYN1_HUMAN Isoform 4 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-3|DYN1_HUMAN Isoform 3 of Dynamin-1 O 0.993146 21.779 0.713213 6.18664 0.134246 35.959 0.993146 21.779 0.00178588 103.23 2 T AGRRSPTSSPTPQ CAMK2;PKA/AKT 0.00111111 0.00178588 103.23 _RSPpTSpSPTPQR_ RS(0.007)PT(0.993)S(0.106)S(0.556)PT(0.338)PQR RS(-21.78)PT(21.78)S(-7.2)S(2.16)PT(-2.16)PQR 4 2 687.28416 -0.2913 421690 53563 0 0 368130 0 0 0 3068 797 780 780 5046 5739;5740 48797 29823 Mix4_TiO2_1_3 1215 48799 29826 Mix4_TiO2_Reinj_1_3 1656 Q05193;Q05193-2;Q05193-4;Q05193-3;Q05193-5 Q05193 Q05193 >sp|Q05193|DYN1_HUMAN Dynamin-1 OS=Homo sapiens GN=DNM1 PE=1 SV=2;>sp|Q05193-2|DYN1_HUMAN Isoform 2 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-4|DYN1_HUMAN Isoform 4 of Dynamin-1 OS=Homo sapiens GN=DNM1;>sp|Q05193-3|DYN1_HUMAN Isoform 3 of Dynamin-1 O 0.604518 4.80371 0.604518 4.80371 0.134246 35.959 0.529699 4.00315 0.00178588 103.23 2 T SPTSSPTPQRRAP CDK1;CDK2;CK1;Proline-directed 0.0057 0.00178588 103.23 _RSPpTSSPpTPQR_ RS(0.086)PT(0.713)S(0.387)S(0.209)PT(0.605)PQR RS(-11.05)PT(6.19)S(-4.8)S(-6.19)PT(4.8)PQR 8 2 687.28416 -0.37922 144240 38306 0 0 105930 0 0 0 3069 798 509 509 6622 7581 67149 41193 Mix4_TiO2_1_5 3538 67150 41195 Mix4_TiO2_Reinj_1_5 4207 Q05209 Q05209 Q05209 >sp|Q05209|PTN12_HUMAN Tyrosine-protein phosphatase non-receptor type 12 OS=Homo sapiens GN=PTPN12 PE=1 SV=2 0.499687 0 0.499687 0 0.215384 40.384 0.0013615 -27.2356 0.000679289 80.158 1 T SNKVSVTPPEESQ CK2;Proline-directed 0.05 0.000679289 80.158 _VpSVTPPEESQNSDTPPRPDR_ VS(0.5)VT(0.5)PPEESQNSDTPPRPDR VS(0)VT(0)PPEES(-30.58)QNS(-35.42)DT(-40.38)PPRPDR 4 3 763.34454 0.21056 0 0 0 0 0 0 0 0 3070 799 13 13 24 32 258 153 Mix4_TiO2_1_5 5612 262 157 Mix4_TiO2_Reinj_1_5 6506 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.99957 33.662 0.99957 33.662 1.18667E-15 149.93 0.994087 22.9323 6.86721E-06 98.828 0.996894 29.8361 3.82093E-22 175.14 0.996361 25.8778 0.0103134 71.846 0.993042 21.5496 5.69392E-10 125.08 1 T DPNLNHTPNSSTK FHA KAPP;NEK6;Proline-directed 0.05 3.82093E-22 175.14 _(ac)AAAYLDPNLNHpTPNSSTK_ AAAYLDPNLNHT(1)PNSSTK AAAY(-147.22)LDPNLNHT(33.66)PNS(-33.66)S(-69.19)T(-69.19)K 12 2 1018.4597 0.027014 1294000 256590 58971 0 667230 0 190470 120770 3071 799 18 18 24 32 259 154 Mix4_TiO2_1_5 5614 262 157 Mix4_TiO2_Reinj_1_5 6506 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.284155 0 0.284155 0 1.18667E-15 149.93 9.26505E-05 -40.3058 6.86721E-06 98.828 0.00103523 -29.8361 3.82093E-22 175.14 0.00785837 -20.995 0.0103134 71.846 0.231271 0 5.69392E-10 125.08 1 T HTPNSSTKTHLGT 3.82093E-22 175.14 _(ac)AAAYLDPNLNHTPNpSSTK_ AAAY(0.046)LDPNLNHT(0.102)PNS(0.284)S(0.284)T(0.284)K AAAY(-7.93)LDPNLNHT(-4.46)PNS(0)S(0)T(0)K 17 3 679.30888 0.058166 0 0 0 0 0 0 0 0 3072 799 914 914 3673 4144 34535 21478 Mix4_TiO2_Reinj_1_1 4927 34530 21466 Mix4_TiO2_1_5 4769 Q05397;Q05397-2 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 0.566634 1.16447 0.460626 -0.685422 9.09601E-17 174.38 0.178195 -6.63873 2.26999E-16 172.06 0.566634 1.16447 3.32926E-12 139.65 0.232696 -5.18179 0.690198 22.035 0.422069 -1.36493 3.28937E-12 139.83 0.263721 -4.45897 1.03092E-08 123.7 1 T EISPPPTANLDRS FHA2 Rad53p 0.114 9.09601E-17 174.38 _LQPQEISPPPpTANLDR_ LQPQEIS(0.433)PPPT(0.567)ANLDR LQPQEIS(-1.16)PPPT(1.16)ANLDR 11 2 928.45112 0.12934 277180 0 0 0 277180 0 0 0 3073 799 394 394 6013 6856;6857 59406 36059 Mix4_InSol_TiO2_1 7331 59417 36065 Mix4_TiO2_Reinj_1_5 6423 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.30308 0 0.248459 0 0.000204101 85.223 0 0 0.0871881 -9.27032 1.49544E-07 104.48 0 0 0.30308 0 0.000263815 81.239 0.189793 -1.0342 0.0149515 70.965 1 T AVSVSETDDYAEI 1.49544E-07 104.48 _THAVSVpSETDDYAEIIDEEDTYTMPSTR_ T(0.015)HAVS(0.076)VS(0.303)ET(0.303)DDY(0.303)AEIIDEEDTYTMPSTR T(-13.18)HAVS(-6)VS(0)ET(0)DDY(0)AEIIDEEDT(-62.96)Y(-66.9)T(-70.47)MPS(-74.61)T(-74.61)R 9 3 1085.7902 0.41264 0 0 0 0 0 0 0 0 3074 799 575 575 6758;6759 7732;7733;7734;7735 68574 42085 Mix4_InSol_TiO2_1 3140 68583 42091 Mix4_InSol_Tio2_Reinj_1 3696 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.920254 11.5639 0.0836429 -9.74368 0.0488772 47.409 0.274924 -2.1002 0.00252985 74.845 0.920254 11.5639 6.87067E-06 147.27 0.366048 -2.35728 2.55156E-06 153.18 1 T RYMEDSTYYKASK PLK1 0.033462 2.55156E-06 153.18 _YM(ox)EDSpTYYKASK_ YMEDS(0.008)T(0.92)Y(0.064)Y(0.007)KASK Y(-81.52)MEDS(-20.41)T(11.56)Y(-11.56)Y(-21.12)KAS(-40.89)K 6 2 791.31257 0.42621 108710 0 0 0 0 0 108710 0 3075 800 507 507 541 615 5104 3135 Mix4_TiO2_Reinj_1_4 8811 5089 3112 Mix4_TiO2_1_4 8231 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.5 0 0.5 0 2.87622E-27 192.73 0.496878 0 0.708823 28.953 0.5 0 4.19236E-22 170.47 0.499725 0 0.501626 33.753 0.5 0 1.8212E-16 152.19 0.499988 0 3.51132E-11 134.34 1 T GESRASTFCGTPD CAMK2 0.042 2.87622E-27 192.73 _ApSTFCGTPDYIAPEILQGLK_ AS(0.5)T(0.5)FCGTPDYIAPEILQGLK AS(0)T(0)FCGT(-82.68)PDY(-113.29)IAPEILQGLK 3 2 1131.0316 0.82573 68830000 5.6466 14212000 0 0 53382000 0 1036700 198500 3076 800 511 511 541 615 5080 3095 Mix4_TiO2_1_1 7486 5089 3112 Mix4_TiO2_1_4 8231 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.751646 9.29786 0.751646 9.29786 2.87622E-27 192.73 0.00561097 -19.4721 0.708823 28.953 0.0910313 -6.98274 4.19236E-22 170.47 0.000339003 -31.6853 0.501626 33.753 0.359765 0.593816 1.8212E-16 152.19 0.0903639 -6.9664 3.51132E-11 134.34 1 T ASTFCGTPDYIAP Proline-directed 0.05 2.87622E-27 192.73 _ASTFCGpTPDYIAPEILQGLK_ AS(0.08)T(0.08)FCGT(0.752)PDY(0.088)IAPEILQGLK AS(-9.73)T(-9.73)FCGT(9.3)PDY(-9.3)IAPEILQGLK 7 3 754.35684 -0.54058 52897 0.0043396 52897 0 0 0 0 0 0 3077 800 295 295 3514;3515 3967;3968 33207 20513 Mix4_InSol_TiO2_1 6575 33172 20491 Mix4_InSol_TiO2_1 6711 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.942538 12.1492 0.0660876 -11.5019 0.0029378 79.546 0.0454434 -13.2233 0.0151528 68.838 0.942538 12.1492 0.00280379 80.43 0.628301 2.27977 0.227969 37.067 1 T EALNQVTQRASRR FHA KAPP 0.155 0.00280379 80.43 _LLAEALNQVpTQRASRR_ LLAEALNQVT(0.943)QRAS(0.057)RR LLAEALNQVT(12.15)QRAS(-12.15)RR 10 4 477.25592 -0.69693 2170000 0 0 0 0 0 667960 1502100 3078 800 609 609 6030 6878 59581 36154 Mix4_TiO2_1_3 7008 59581 36154 Mix4_TiO2_1_3 7008 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.999999 59.1212 0.999999 59.1212 0.00785173 61.542 0.999925 41.2607 0.0682945 41.261 1 T FKTINWTLLEKRR CK2 0.117 0.00785173 61.542 _TINWpTLLEK_ TINWT(1)LLEK T(-59.12)INWT(59.12)LLEK 5 2 599.2994 -1.1603 51551 8943.2 0 0 42608 0 0 0 3079 801 262 262 2426;6372 2749;7288 64359 39492 Mix4_InSol_Tio2_Reinj_3 3519 64360 39493 Mix4_TiO2_1_3 5822 Q06210;Q06210-2 Q06210 Q06210 >sp|Q06210|GFPT1_HUMAN Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 PE=1 SV=3;>sp|Q06210-2|GFPT1_HUMAN Isoform 2 of Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens GN=GFPT1 0.470545 0 0.00139566 -28.546 3.94701E-06 142.94 0.437011 0 0.860998 5.957 0.456479 0 0.00022029 112.27 0.117935 -8.45014 0.00035189 107.75 0.470545 0 0.00052565 101.78 1 T LSRVDSTTCLFPV FHA2 Rad53p 0.114 3.94701E-06 142.94 _VDpSTTCLFPVEEK_ VDS(0.471)T(0.471)T(0.059)CLFPVEEK VDS(0)T(0)T(-9.02)CLFPVEEK 4 2 802.84932 -0.38857 0 0 0 0 0 0 0 0 3080 807 56 56 4908 5580 47089 28791 Mix4_InSol_TiO2_1 3550 47092 28794 Mix4_TiO2_Reinj_1_4 3105 Q07352 Q07352 Q07352 >sp|Q07352|TISB_HUMAN Zinc finger protein 36, C3H1 type-like 1 OS=Homo sapiens GN=ZFP36L1 PE=1 SV=1 0.513015 0.642642 0 0 0.304743 -0.918586 0.00586227 63.777 0.513015 0.642642 0.392411 17.59 0.210549 -2.42913 0.743466 2.4291 1 T PRRHSVTLPSSKF FHA KAPP 0.155 0.00586227 63.777 _RHSVpTLPSSK_ RHS(0.442)VT(0.513)LPS(0.022)S(0.022)K RHS(-0.64)VT(0.64)LPS(-13.62)S(-13.62)K 5 3 397.86757 -1.4177 41481 0 0 0 0 0 41481 0 3081 809 164 164 3244 3678 30681 19053 Mix4_TiO2_Reinj_1_5 8609 30680 19050 Mix4_TiO2_1_5 7798 Q07912-3;Q07912;Q07912-2 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3;>sp|Q07912-2|ACK1_HUMAN Isoform 2 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 0.5 0 0.5 0 1.65582E-25 162.11 0.5 0 7.32017E-19 155.54 1 T QSTFRKTSPAPGG FHA KAPP;NIMA;PKA 0.001741464 1.65582E-25 162.11 _KpTSPAPGGPAGEGPLQSLTCLIGEK_ KT(0.5)S(0.5)PAPGGPAGEGPLQSLTCLIGEK KT(0)S(0)PAPGGPAGEGPLQS(-128.9)LT(-154.9)CLIGEK 2 3 849.08378 -0.32833 918620 245850 0 0 672770 0 0 0 3082 809 892 892 3742 4221 35360 21867 Mix4_InSol_Tio2_Reinj_1 5319 35358 21865 Mix4_InSol_TiO2_1 5353 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.276286 0.607564 0.0907523 -3.02404 0.00618544 73.311 0.276286 0.607564 0.401632 36.069 1 T SSSPGKTMPTTQS 0.00618544 73.311 _LSSSPGKpTMPTTQSFASDPK_ LS(0.24)S(0.24)S(0.24)PGKT(0.276)MPT(0.002)T(0.001)QSFASDPK LS(-0.61)S(-0.61)S(-0.61)PGKT(0.61)MPT(-22.63)T(-22.89)QS(-36.07)FAS(-36.07)DPK 8 3 716.32906 -0.061775 0 0 0 0 0 0 0 0 3083 813 286 286 4561;5312 5180;6048 51558 31554 Mix4_TiO2_Reinj_1_3 8360 51556 31552 Mix4_TiO2_1_3 7710 Q08499-6;Q08499;Q08499-11;Q08499-9;Q08499-10;Q08499-2;Q08499-3;Q08499-4;Q08499-8;Q08499-5 Q08499-6 Q08499-6 >sp|Q08499-6|PDE4D_HUMAN Isoform hPDE4D5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D;>sp|Q08499|PDE4D_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Homo sapiens GN=PDE4D PE=1 SV=2;>sp|Q08499-11|PDE4D_HUMAN Isoform 0.515431 0.315485 0.193317 -6.20432 7.25883E-08 111.51 0.515431 0.315485 0.00576067 82.241 1 T VEIPSPTQKEKEK CK2 0.117 7.25883E-08 111.51 _SGNQVSEFISNTFLDKQHEVEIPSPpTQK_ SGNQVS(0.002)EFIS(0.002)NT(0.001)FLDKQHEVEIPS(0.479)PT(0.515)QK S(-37.84)GNQVS(-24.32)EFIS(-23.22)NT(-28.06)FLDKQHEVEIPS(-0.32)PT(0.32)QK 26 4 810.63686 0.80075 739680 0 0 0 739680 0 0 0 3084 816 21 21 3243;4930 3677;5606 47407 28960 Mix4_TiO2_Reinj_1_5 6172 30668 19046 Mix4_TiO2_Reinj_1_3 6520 Q09161 Q09161 Q09161 >sp|Q09161|NCBP1_HUMAN Nuclear cap-binding protein subunit 1 OS=Homo sapiens GN=NCBP1 PE=1 SV=1 0.862945 7.99822 0.0288608 -15.2696 5.71869E-06 102.07 0 0 0.862945 7.99822 2.93749E-11 136.76 0.49998 0 0.0535403 56.132 0.117722 -8.12538 0.14618 44.801 1 T PHKRRKTSDANET CAMK2;FHA KAPP;PKA 0.003024 2.93749E-11 136.76 _RKpTSDANETEDHLESLICK_ RKT(0.863)S(0.137)DANETEDHLESLICK RKT(8)S(-8)DANET(-35.73)EDHLES(-62.82)LICK 3 3 776.01754 -0.35876 467770 0 0 0 206080 0 261690 0 3085 816 27 27 3243;4930 3677;5606 47404 28957 Mix4_InSol_Tio2_Reinj_1 6788 30668 19046 Mix4_TiO2_Reinj_1_3 6520 Q09161 Q09161 Q09161 >sp|Q09161|NCBP1_HUMAN Nuclear cap-binding protein subunit 1 OS=Homo sapiens GN=NCBP1 PE=1 SV=1 0.764531 8.12538 2.63221E-05 -45.6695 5.71869E-06 102.07 0 0 0.00462355 -20.2996 2.93749E-11 136.76 3.87173E-05 -41.1105 0.0535403 56.132 0.764531 8.12538 0.14618 44.801 1 T TSDANETEDHLES 2.93749E-11 136.76 _RKTSDANEpTEDHLESLICK_ RKT(0.118)S(0.118)DANET(0.765)EDHLESLICK RKT(-8.13)S(-8.13)DANET(8.13)EDHLES(-44.8)LICK 9 3 776.01754 -0.015855 140890 0 0 0 0 0 0 140890 3086 817 218 218 3630 4091 34112 21053 Mix4_TiO2_1_1 3734 34115 21056 Mix4_TiO2_Reinj_1_2 4146 Q09666 Q09666 Q09666 >sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens GN=AHNAK PE=1 SV=2 0.446348 0.997479 0.446348 0.997479 0.061873 54.965 0 0 0.155661 -7.2134 0.000624455 91.295 0 0 0 0 1 T SGAASPTGSAVDI FHA KAPP 0.155 0.000624455 91.295 _LPSGSGAASPpTGSAVDIR_ LPS(0.091)GS(0.091)GAAS(0.355)PT(0.446)GS(0.016)AVDIR LPS(-6.89)GS(-6.89)GAAS(-1)PT(1)GS(-14.41)AVDIR 11 2 861.90655 0.19447 0 0 0 0 0 0 0 0 3087 827 106 106 1713 1928 15757 9544 Mix4_TiO2_Reinj_1_4 1308 15757 9544 Mix4_TiO2_Reinj_1_4 1308 Q12834 Q12834 Q12834 >sp|Q12834|CDC20_HUMAN Cell division cycle protein 20 homolog OS=Homo sapiens GN=CDC20 PE=1 SV=2 0.746911 4.71431 0.746911 4.71431 0.000475963 103.49 0 0 0 0 1 T QPENSQTPTKKEH CDK1;CDK2;Proline-directed 0.0057 0.000475963 103.49 _ENQPENSQpTPTKK_ ENQPENS(0.001)QT(0.747)PT(0.252)KK ENQPENS(-29.52)QT(4.71)PT(-4.71)KK 9 2 790.85124 0.95426 121200 0 0 0 121200 0 0 0 3088 829 329 329 6371 7287 64321 39459 Mix4_TiO2_1_5 3820 64329 39471 Mix4_TiO2_Reinj_1_1 3962 Q12893 Q12893 Q12893 >sp|Q12893|TM115_HUMAN Transmembrane protein 115 OS=Homo sapiens GN=TMEM115 PE=1 SV=1 0.999998 57.7869 0.999998 57.7869 1.05479E-05 103.33 0.995984 23.9623 0.00823431 74.662 0.999923 41.1062 5.41209E-06 110.53 0.732687 4.46057 0.699587 21.681 0 0 1 T PSDKAPTPPGKGA Proline-directed 0.05 5.41209E-06 110.53 _VDSPLPSDKAPpTPPGK_ VDSPLPSDKAPT(1)PPGK VDS(-69.61)PLPS(-57.79)DKAPT(57.79)PPGK 12 3 562.60972 -0.026025 7730700 1811400 426500 0 5482100 10634 0 0 3089 833 486 486 1250;2162 1409;2448 19867 12127 Mix4_TiO2_1_5 6941 19867 12127 Mix4_TiO2_1_5 6941 Q12906;Q12906-3;Q12906-2;Q12906-5 Q12906 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 PE=1 SV=3;>sp|Q12906-3|ILF3_HUMAN Isoform 3 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-2|ILF3_HUMAN Isoform DRBP76 of Interleukin enhancer- 0.837975 7.19732 0.837975 7.19732 9.7843E-06 103.58 0 0 0.151542 -4.82205 1.26225E-05 101.46 0 0 1 T EDSAEETEAKPAV 9.7843E-06 103.58 _GEDSAEEpTEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTK_ GEDS(0.16)AEET(0.838)EAKPAVVAPAPVVEAVS(0.002)TPSAAFPSDATAEQGPILTK GEDS(-7.2)AEET(7.2)EAKPAVVAPAPVVEAVS(-26.6)T(-33.25)PS(-45.58)AAFPS(-61.5)DAT(-65.77)AEQGPILT(-80.92)K 8 4 1129.548 0.087806 2576300 0.75491 2576300 0 0 0 0 0 0 3090 834 486 486 1249 1406 11729 7196 Mix4_TiO2_Reinj_1_5 7203 11729 7196 Mix4_TiO2_Reinj_1_5 7203 Q12906-6;Q12906-4 Q12906-6 Q12906-6 >sp|Q12906-6|ILF3_HUMAN Isoform 6 of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3;>sp|Q12906-4|ILF3_HUMAN Isoform ILF3-A of Interleukin enhancer-binding factor 3 OS=Homo sapiens GN=ILF3 0.620933 4.51186 0.100087 -5.84239 0.0124904 79.646 0 0 0.620933 4.51186 0.00236984 95.222 0 0 0 0 1 T EDSAEETEAKPAV 0.00236984 95.222 _DSSKGEDSAEEpTEAKPAVVAPAPVVEAVSTPSAAFPSDATAENVK_ DS(0.079)S(0.079)KGEDS(0.22)AEET(0.621)EAKPAVVAPAPVVEAVS(0.001)TPSAAFPSDATAENVK DS(-8.94)S(-8.94)KGEDS(-4.51)AEET(4.51)EAKPAVVAPAPVVEAVS(-28.9)T(-38.61)PS(-51.88)AAFPS(-62.93)DAT(-66.8)AENVK 12 4 1134.7852 0.65075 1911900 6.057 0 0 0 1911900 0 0 0 3091 843 370 370 838;839 948;949 7908 4704 Mix4_TiO2_Reinj_2_1 4662 7896 4685 Mix4_TiO2_Reinj_1_4 7785 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.853114 7.79958 0.0837347 -9.44528 0.00279505 77.163 0.498161 0 0.000271109 91.407 0.853114 7.79958 0.000380007 82.769 1 T KDFYLATSPPDSF 0.000271109 91.407 _DFYLApTSPPDSFLDDHHLTRPHPER_ DFYLAT(0.853)S(0.142)PPDS(0.005)FLDDHHLTRPHPER DFY(-45.21)LAT(7.8)S(-7.8)PPDS(-22.1)FLDDHHLT(-54.51)RPHPER 6 3 1015.1293 0.095788 147580 0 0 0 0 147580 0 0 3092 843 503 503 5335;5336;5362 6076;6077;6104;6105 52128 31891 Mix4_InSol_Tio2_Reinj_1 4853 52133 31896 Mix4_TiO2_1_4 3985 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.758509 4.97107 0.776555 6.76847 1.84428E-15 146.17 0 0 0.324605 -2.92616 1.6048E-15 147.56 0.510467 -0.460811 1.23591E-15 149.63 0.758509 4.97107 1.43005E-15 148.55 1 T TEAKSGTATPQRS 6.55076E-21 161.88 _SIDDEITEAKSGpTATPQR_ SIDDEITEAKS(0.241)GT(0.759)ATPQR S(-96.73)IDDEIT(-44.6)EAKS(-4.97)GT(4.97)AT(-67.9)PQR 13 3 666.97204 1.1693 974420 0 0 0 0 0 0 974420 3093 843 505 505 5335;5336;5362 6076;6077;6104;6105 51819 31728 Mix4_InSol_TiO2_1 1141 52133 31896 Mix4_TiO2_1_4 3985 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.999993 51.7554 0.999731 35.034 1.84428E-15 146.17 0 0 0.99999 49.4191 7.62144E-10 120.92 0.999993 51.7554 1.85236E-16 155.62 0.999993 54.4036 1.43005E-15 148.55 1 T AKSGTATPQRSGS CDK1;CDK2;Proline-directed 0.0057 6.55076E-21 161.88 _SGTApTPQR_ SGTAT(1)PQR S(-65.38)GT(-51.76)AT(51.76)PQR 5 2 449.19493 -0.28711 242970 0 0 0 0 0 67332 175640 3094 843 497 497 5362 6104;6105 52136 31899 Mix4_TiO2_Reinj_1_4 4518 52133 31896 Mix4_TiO2_1_4 3985 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.91616 10.5921 0.253905 -2.61405 6.55076E-21 161.88 0 0 0.91616 10.5921 1.6048E-15 147.56 0.583925 1.8873 1.85236E-16 155.62 0.0890883 -6.14096 1.43005E-15 148.55 1 T SIDDEITEAKSGT 6.55076E-21 161.88 _SIDDEIpTEAKSGTATPQR_ SIDDEIT(0.916)EAKS(0.08)GT(0.004)ATPQR S(-34.6)IDDEIT(10.59)EAKS(-10.59)GT(-24.08)AT(-71.43)PQR 7 2 999.95442 0.16318 2170200 0 0 0 925830 0 1244400 0 3095 843 537 537 5701 6494;6495 55883 34216 Mix4_TiO2_Reinj_1_4 7214 55880 34213 Mix4_TiO2_Reinj_1_3 7242 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.239023 0 0.000979442 -29.3022 8.88907E-07 100.64 0.239023 0 2.27979E-55 237.53 1 T SSEVSLTSSVTSL 2.27979E-55 237.53 _SSEVSLpTSSVTSLDSSPVDLTPR_ S(0.001)S(0.001)EVS(0.004)LT(0.239)S(0.239)S(0.239)VT(0.239)S(0.038)LDSSPVDLTPR S(-25.64)S(-24.86)EVS(-17.72)LT(0)S(0)S(0)VT(0)S(-7.94)LDS(-45.3)S(-58.96)PVDLT(-89.91)PR 7 3 815.38618 0.39377 0 0 0 0 0 0 0 0 3096 843 541 541 5701 6494;6495 55883 34216 Mix4_TiO2_Reinj_1_4 7214 55880 34213 Mix4_TiO2_Reinj_1_3 7242 Q13131-2;Q13131 Q13131-2 Q13131-2 >sp|Q13131-2|AAPK1_HUMAN Isoform 2 of 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1;>sp|Q13131|AAPK1_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens GN=PRKAA1 PE=1 SV=4 0.239023 0 0.0273752 -14.8384 8.88907E-07 100.64 0.239023 0 2.27979E-55 237.53 1 T SLTSSVTSLDSSP CK1;CK2;FHA1 Rad53p 0.059 2.27979E-55 237.53 _SSEVSLpTSSVTSLDSSPVDLTPR_ S(0.001)S(0.001)EVS(0.004)LT(0.239)S(0.239)S(0.239)VT(0.239)S(0.038)LDSSPVDLTPR S(-25.64)S(-24.86)EVS(-17.72)LT(0)S(0)S(0)VT(0)S(-7.94)LDS(-45.3)S(-58.96)PVDLT(-89.91)PR 11 3 815.38618 0.39377 0 0 0 0 0 0 0 0 3097 848 384 384 3944;3945;3946 4492;4493;4494;4495 37420 23006 Mix4_InSol_Tio2_Reinj_1 8395 37409 22997 Mix4_TiO2_1_4 1526 Q13188 Q13188 Q13188 >sp|Q13188|STK3_HUMAN Serine/threonine-protein kinase 3 OS=Homo sapiens GN=STK3 PE=1 SV=2 0.448291 0 0.0109021 -19.5771 0.00450002 69.92 0.0294727 -15.1759 0.0131236 58.731 0.216486 -4.69464 0.411677 37.794 0.448291 0 1.47514 16.5 1 T TMKRNATSPQVQR CAMK2;CHK1;PKA 0.003024 0.00450002 69.92 _NApTSPQVQRPSFMDYFDKQDFK_ NAT(0.448)S(0.448)PQVQRPS(0.093)FMDY(0.01)FDKQDFK NAT(0)S(0)PQVQRPS(-6.81)FMDY(-16.5)FDKQDFK 3 3 910.40703 -0.29722 0 0 0 0 0 0 0 0 3098 850 20 20 583 667 5497 3281 Mix4_TiO2_Reinj_1_1 2392 5496 3280 Mix4_TiO2_1_5 2106 Q13233 Q13233 Q13233 >sp|Q13233|M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens GN=MAP3K1 PE=1 SV=4 0.91622 10.3886 0.582815 1.45201 0.0107355 72.588 0 0 0.91622 10.3886 0.0558905 52.608 0 0 0.560816 1.06173 0.355717 28.39 0.136605 -8.00744 0.0232687 60.718 1 T FPGARATSPEAGG CK2;PKA 0.042 0.0107355 72.588 _ApTSPEAGGGGGALK_ AT(0.916)S(0.084)PEAGGGGGALK AT(10.39)S(-10.39)PEAGGGGGALK 2 2 626.7821 -0.1011 1598300 82134 0 0 1128600 0 387580 0 3099 863 315 315 5716;5717 6513;6514 56123 34326 Mix4_InSol_TiO2_1 4924 56120 34325 Mix4_TiO2_Reinj_1_5 4779 Q13435 Q13435 Q13435 >sp|Q13435|SF3B2_HUMAN Splicing factor 3B subunit 2 OS=Homo sapiens GN=SF3B2 PE=1 SV=2 0.593835 5.98878 0 0 3.34987E-09 -84.6518 4.67295E-21 158.4 0.593835 5.98878 1.03349 21.365 0.0247672 -14.9943 0.143284 46.19 1 T SETEEDTVSVSKK PLK1 0.033462 4.67295E-21 158.4 _SSLGQSASETEEDpTVSVSKK_ S(0.004)S(0.004)LGQS(0.15)AS(0.112)ET(0.112)EEDT(0.594)VS(0.02)VS(0.004)KK S(-21.37)S(-21.37)LGQS(-5.99)AS(-7.25)ET(-7.25)EEDT(5.99)VS(-14.79)VS(-21.37)KK 14 3 716.98965 -0.5371 149750 0 0 0 0 0 149750 0 3100 865 1341 1341 565;566 647;648 5353 3219 Mix4_TiO2_1_1 2225 5339 3218 Mix4_TiO2_Reinj_2_1 2443 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.703391 6.76043 0.703391 6.76043 0.168149 34.242 0.000326131 -34.2415 0.168149 34.241 0.00352064 -21.5082 0.183508 35.243 6.79415E-09 -81.1694 0.00605942 81.169 0 0 0 0 1 T SDRHRATGAALTP FHA KAPP;PKA 0.042 0.00605942 81.169 _ApTGAALTPTEERR_ AT(0.703)GAALT(0.148)PT(0.148)EERR AT(6.76)GAALT(-6.76)PT(-6.76)EERR 2 2 726.84576 0.028559 33547 33547 0 0 0 0 0 0 3101 865 1346 1346 565;566 647;648 5337 3216 Mix4_TiO2_1_1 2309 5339 3218 Mix4_TiO2_Reinj_2_1 2443 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.924431 10.8953 0.924431 10.8953 0.168149 34.242 0.866046 8.11644 0.168149 34.241 0.49824 0 0.183508 35.243 0.889361 9.0517 0.00605942 81.169 0 0 0 0 1 T ATGAALTPTEERR CK2;Proline-directed 0.05 0.00605942 81.169 _ATGAALpTPTEER_ ATGAALT(0.924)PT(0.075)EER AT(-34.24)GAALT(10.9)PT(-10.9)EER 7 2 648.79521 -0.11543 68485 33217 7806.6 0 0 27462 0 0 3102 865 1348 1348 565;566 647;648 5354 3220 Mix4_TiO2_Reinj_1_1 2651 5339 3218 Mix4_TiO2_Reinj_2_1 2443 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.49824 0 0.148304 -6.76043 0.168149 34.242 0.133628 -8.11644 0.168149 34.241 0.49824 0 0.183508 35.243 0.110639 -9.0517 0.00605942 81.169 0 0 0 0 1 T GAALTPTEERRTS NEK6 0.076 0.00605942 81.169 _ATGAALpTPTEERR_ AT(0.004)GAALT(0.498)PT(0.498)EERR AT(-21.51)GAALT(0)PT(0)EERR 9 2 726.84576 -0.10649 0 0 0 0 0 0 0 0 3103 865 1295 1295 6556 7499 66314 40715 Mix4_TiO2_1_1 2174 66317 40720 Mix4_TiO2_Reinj_1_1 2565 Q13459;Q13459-2 Q13459 Q13459 >sp|Q13459|MYO9B_HUMAN Myosin-IXb OS=Homo sapiens GN=MYO9B PE=1 SV=2;>sp|Q13459-2|MYO9B_HUMAN Isoform Short of Myosin-IXb OS=Homo sapiens GN=MYO9B 0.365981 0 0.365981 0 0.00237725 80.302 0 0 8.23068E-05 -40.827 8.84562E-20 176.91 0 0 7.26848E-06 -51.3853 0.0189164 65.653 1 T DSPGGSTQIQRYL 8.84562E-20 176.91 _VQEKPDSPGGpSTQIQR_ VQEKPDS(0.268)PGGS(0.366)T(0.366)QIQR VQEKPDS(-1.35)PGGS(0)T(0)QIQR 12 2 903.92273 -0.0017073 0 0 0 0 0 0 0 0 3104 867 514 514 4450;5430 5061;6180;6181 52979 32376 Mix4_TiO2_Reinj_1_3 7579 52978 32375 Mix4_TiO2_1_3 6890 Q13470;Q13470-2 Q13470 Q13470 >sp|Q13470|TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 PE=1 SV=3;>sp|Q13470-2|TNK1_HUMAN Isoform 2 of Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens GN=TNK1 0.69589 6.60544 0.298055 -3.64204 3.8925E-07 110.46 0.69589 6.60544 0.00650189 79.581 0 0 1 T SLGPRPTGGGSSP PKA 0.042 3.8925E-07 110.46 _SLESVLSLGPRPpTGGGSSPPEIR_ SLESVLSLGPRPT(0.696)GGGS(0.152)S(0.152)PPEIR S(-64.84)LES(-64.84)VLS(-55.9)LGPRPT(6.61)GGGS(-6.61)S(-6.61)PPEIR 13 3 791.73184 0.70599 194190 0 0 0 194190 0 0 0 3105 868 64 64 655 753 6322 3763 Mix4_TiO2_Reinj_1_3 1223 6322 3763 Mix4_TiO2_Reinj_1_3 1223 Q13488 Q13488 Q13488 >sp|Q13488|VPP3_HUMAN V-type proton ATPase 116 kDa subunit a isoform 3 OS=Homo sapiens GN=TCIRG1 PE=1 SV=3 0.5 0 0.5 0 0.0245896 60.868 0.5 0 1.34479 3.2623 0 0 1 T CEELEKTFTFLQE NEK6;PLK1 0.033462 0.0245896 60.868 _CEELEKpTFTFLQEEVR_ CEELEKT(0.5)FT(0.5)FLQEEVR CEELEKT(0)FT(0)FLQEEVR 7 2 1069.4792 -0.88108 579770 0 0 0 569030 0 10734 0 3106 868 66 66 655 753 6322 3763 Mix4_TiO2_Reinj_1_3 1223 6322 3763 Mix4_TiO2_Reinj_1_3 1223 Q13488 Q13488 Q13488 >sp|Q13488|VPP3_HUMAN V-type proton ATPase 116 kDa subunit a isoform 3 OS=Homo sapiens GN=TCIRG1 PE=1 SV=3 0.5 0 0.5 0 0.0245896 60.868 0.5 0 1.34479 3.2623 0 0 1 T ELEKTFTFLQEEV CHK1;PKD 0.020748 0.0245896 60.868 _CEELEKpTFTFLQEEVR_ CEELEKT(0.5)FT(0.5)FLQEEVR CEELEKT(0)FT(0)FLQEEVR 9 2 1069.4792 -0.88108 579770 0 0 0 569030 0 10734 0 3107 869 269 269 3774;5670 4264;4265;6456;6457 55491 33992 Mix4_TiO2_2_4 2942 55483 33982 Mix4_InSol_Tio2_Reinj_1 3905 Q13501;Q13501-2 Q13501 Q13501 >sp|Q13501|SQSTM_HUMAN Sequestosome-1 OS=Homo sapiens GN=SQSTM1 PE=1 SV=1;>sp|Q13501-2|SQSTM_HUMAN Isoform 2 of Sequestosome-1 OS=Homo sapiens GN=SQSTM1 0.980886 17.6883 0.823254 3.71281 1.19301E-06 116.43 0.980886 17.6883 0.0947839 49.565 0.998906 29.6193 1.73737E-27 131.16 0.301474 -1.69 0.00101431 90.994 0.854228 7.70759 5.09511E-09 130.64 1 T GKRSRLTPVSPES CK1;FHA KAPP;PKA;Proline-directed 0.042 5.09511E-09 130.64 _SRLpTPVSPESSSTEEK_ S(0.017)RLT(0.981)PVS(0.002)PESSSTEEK S(-17.69)RLT(17.69)PVS(-26.17)PES(-49.56)S(-49.56)S(-49.56)T(-49.56)EEK 4 3 605.27869 0.24709 798880 0 35258 0 739050 0 0 24570 3108 872 1989 1989 2519 2863 23708 14732 Mix4_TiO2_Reinj_1_5 6515 23705 14728 Mix4_TiO2_1_1 5261 Q13535;Q13535-3;Q13535-2 Q13535 Q13535 >sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3;>sp|Q13535-3|ATR_HUMAN Isoform 3 of Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR;>sp|Q13535-2|ATR_HUMAN Isoform 2 of Serine/threonine-protein kinase ATR 1 90.5879 1 62.2872 1.33653E-12 149.85 0 0 1 90.5879 9.91942E-09 124.24 1 29.5459 0.475632 29.546 1 T CFPENETPPEGKN CK2;Proline-directed 0.05 1.33653E-12 149.85 _GVELCFPENEpTPPEGK_ GVELCFPENET(1)PPEGK GVELCFPENET(90.59)PPEGK 11 2 941.90007 0.26234 1520800 395730 0 0 885100 0 239990 0 3109 875 382 382 2474;2476 2811;2813 23243 14491 Mix4_TiO2_Reinj_1_3 3320 23241 14489 Mix4_TiO2_1_4 2764 Q13555-4 Q13555-4 Q13555-4 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.869811 8.27866 0.499906 0 1.6626E-20 191.78 0 0 0.869811 8.27866 9.04602E-20 176.5 0 0 0.424963 0 0.00327354 78.056 0.251955 -2.05972 0.0181031 64.951 1 T DGIKGSTESCNTT 1.6626E-20 191.78 _GSpTESCNTTTEDEDLK_ GS(0.129)T(0.87)ES(0.001)CNTTTEDEDLK GS(-8.28)T(8.28)ES(-29.85)CNT(-79.6)T(-86.67)T(-94.8)EDEDLK 3 2 933.85098 -0.31971 472410 0.21034 241270 0 0 231150 0 0 0 3110 875 387 387 2474;2476 2811;2813 23262 14497 Mix4_InSol_TiO2_1 4326 23241 14489 Mix4_TiO2_1_4 2764 Q13555-4 Q13555-4 Q13555-4 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.498029 0 0.0774389 -7.80564 1.6626E-20 191.78 0 0 0.073192 -8.01496 9.04602E-20 176.5 0 0 0.498029 0 0.00327354 78.056 0.404851 2.05972 0.0181031 64.951 1 T STESCNTTTEDED CK1;CK2 0.081 1.6626E-20 191.78 _GSTESCNpTTTEDEDLKVR_ GSTES(0.001)CNT(0.498)T(0.498)T(0.002)EDEDLKVR GS(-39.69)T(-39.69)ES(-25.55)CNT(0)T(0)T(-23.08)EDEDLKVR 8 3 707.95958 -0.4821 0 0 0 0 0 0 0 0 0 3111 875 388 388 2474;2476 2811;2813 23242 14490 Mix4_TiO2_Reinj_1_3 3206 23241 14489 Mix4_TiO2_1_4 2764 Q13555-4 Q13555-4 Q13555-4 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.692539 4.6867 0.358848 -1.14613 1.6626E-20 191.78 0 0 0.692539 4.6867 9.04602E-20 176.5 0 0 0.498029 0 0.00327354 78.056 0.331845 0 0.0181031 64.951 1 T TESCNTTTEDEDL CK2;FHA1 Rad53p 0.059 1.6626E-20 191.78 _GSTESCNTpTTEDEDLK_ GSTESCNT(0.072)T(0.693)T(0.235)EDEDLK GS(-54.04)T(-54.04)ES(-65.42)CNT(-9.83)T(4.69)T(-4.69)EDEDLK 9 2 933.85098 0.46117 80729 0.035944 0 0 0 80729 0 0 0 3112 875 389 389 2474;2476 2811;2813 23244 14493 Mix4_TiO2_Reinj_1_4 3165 23241 14489 Mix4_TiO2_1_4 2764 Q13555-4 Q13555-4 Q13555-4 >sp|Q13555-4|KCC2G_HUMAN Isoform 4 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G 0.463404 0 0.0606519 -8.86679 1.6626E-20 191.78 0 0 0.463404 0 9.04602E-20 176.5 0 0 0.103657 -4.50804 0.00327354 78.056 0.331845 0 0.0181031 64.951 1 T ESCNTTTEDEDLK CK2 0.117 1.6626E-20 191.78 _GSTESCNTpTTEDEDLK_ GSTESCNT(0.073)T(0.463)T(0.463)EDEDLK GS(-76.64)T(-76.64)ES(-66.31)CNT(-8.01)T(0)T(0)EDEDLK 10 2 933.85098 0.68991 0 0 0 0 0 0 0 0 0 3113 876;877 403;348 2474;2475 2811;2812 23243 14491 Mix4_TiO2_Reinj_1_3 3320 23241 14489 Mix4_TiO2_1_4 2764 Q13555-6;Q13555-7;Q13555-3 Q13555-6;Q13555-7 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.869811 8.27866 0.499906 0 1.6626E-20 191.78 0 0 0.869811 8.27866 9.04602E-20 176.5 0.00159613 -26.6001 0.127218 49.261 0 0 1 T DGIKGSTESCNTT 1.6626E-20 191.78 _GSpTESCNTTTEDEDLK_ GS(0.129)T(0.87)ES(0.001)CNTTTEDEDLK GS(-8.28)T(8.28)ES(-29.85)CNT(-79.6)T(-86.67)T(-94.8)EDEDLK 3 2 933.85098 -0.31971 472410 0.34619 241270 0 0 231150 0 0 0 3114 876;877 408;353 2474;2475 2811;2812 23255 14496 Mix4_InSol_TiO2_1 5218 23241 14489 Mix4_TiO2_1_4 2764 Q13555-6;Q13555-7;Q13555-3 Q13555-6;Q13555-7 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.729585 8.92399 3.83104E-09 -81.1484 1.6626E-20 191.78 0 0 0.073192 -8.01496 9.04602E-20 176.5 0.729585 8.92399 0.127218 49.261 0 0 1 T STESCNTTTEDED CK1;CK2 0.081 1.6626E-20 191.78 _GSTESCNpTTTEDEDLKAAPLR_ GST(0.002)ES(0.082)CNT(0.73)T(0.093)T(0.093)EDEDLKAAPLR GS(-34.4)T(-26.6)ES(-9.51)CNT(8.92)T(-8.92)T(-8.92)EDEDLKAAPLR 8 3 792.34046 0.33785 122800 0.089987 0 0 0 0 0 122800 0 3115 876;877 409;354 2474;2475 2811;2812 23242 14490 Mix4_TiO2_Reinj_1_3 3206 23241 14489 Mix4_TiO2_1_4 2764 Q13555-6;Q13555-7;Q13555-3 Q13555-6;Q13555-7 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.692539 4.6867 5.37097E-10 -89.681 1.6626E-20 191.78 0 0 0.692539 4.6867 9.04602E-20 176.5 0.093471 -8.92399 0.127218 49.261 0 0 1 T TESCNTTTEDEDL CK2;FHA1 Rad53p 0.059 1.6626E-20 191.78 _GSTESCNTpTTEDEDLK_ GSTESCNT(0.072)T(0.693)T(0.235)EDEDLK GS(-54.04)T(-54.04)ES(-65.42)CNT(-9.83)T(4.69)T(-4.69)EDEDLK 9 2 933.85098 0.46117 80729 0.05916 0 0 0 80729 0 0 0 3116 876;877 410;355 2474;2475 2811;2812 23244 14493 Mix4_TiO2_Reinj_1_4 3165 23241 14489 Mix4_TiO2_1_4 2764 Q13555-6;Q13555-7;Q13555-3 Q13555-6;Q13555-7 >sp|Q13555-6|KCC2G_HUMAN Isoform 6 of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-7|KCC2G_HUMAN Isoform gamma F of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens 0.463404 0 7.77146E-11 -98.0765 1.6626E-20 191.78 0 0 0.463404 0 9.04602E-20 176.5 0.093471 -8.92399 0.127218 49.261 0 0 1 T ESCNTTTEDEDLK CK2 0.117 1.6626E-20 191.78 _GSTESCNTpTTEDEDLK_ GSTESCNT(0.073)T(0.463)T(0.463)EDEDLK GS(-76.64)T(-76.64)ES(-66.31)CNT(-8.01)T(0)T(0)EDEDLK 10 2 933.85098 0.68991 0 0 0 0 0 0 0 0 0 3117 878 357 357 2474;2475;4309 2811;2812;4902 23243 14491 Mix4_TiO2_Reinj_1_3 3320 23241 14489 Mix4_TiO2_1_4 2764 Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-9 Q13555-9 >sp|Q13555-9|KCC2G_HUMAN Isoform gamma D of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-8|KCC2G_HUMAN Isoform gamma E of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sa 0.869811 8.27866 0.499906 0 1.6626E-20 191.78 0 0 0.869811 8.27866 9.04602E-20 176.5 0.00159613 -26.6001 0.127218 49.261 0 0 1 T DGIKGSTESCNTT 1.6626E-20 191.78 _GSpTESCNTTTEDEDLK_ GS(0.129)T(0.87)ES(0.001)CNTTTEDEDLK GS(-8.28)T(8.28)ES(-29.85)CNT(-79.6)T(-86.67)T(-94.8)EDEDLK 3 2 933.85098 -0.31971 472410 0.34619 241270 0 0 231150 0 0 0 3118 878 362 362 2474;2475;4309 2811;2812;4902 23255 14496 Mix4_InSol_TiO2_1 5218 23241 14489 Mix4_TiO2_1_4 2764 Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-9 Q13555-9 >sp|Q13555-9|KCC2G_HUMAN Isoform gamma D of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-8|KCC2G_HUMAN Isoform gamma E of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sa 0.729585 8.92399 0.0200188 -13.3526 1.6626E-20 191.78 0 0 0.073192 -8.01496 9.04602E-20 176.5 0.729585 8.92399 0.127218 49.261 0 0 1 T STESCNTTTEDED CK1;CK2 0.081 1.6626E-20 191.78 _GSTESCNpTTTEDEDLKAAPLR_ GST(0.002)ES(0.082)CNT(0.73)T(0.093)T(0.093)EDEDLKAAPLR GS(-34.4)T(-26.6)ES(-9.51)CNT(8.92)T(-8.92)T(-8.92)EDEDLKAAPLR 8 3 792.34046 0.33785 122800 0.089987 0 0 0 0 0 122800 0 3119 878 363 363 2474;2475;4309 2811;2812;4902 23242 14490 Mix4_TiO2_Reinj_1_3 3206 23241 14489 Mix4_TiO2_1_4 2764 Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-9 Q13555-9 >sp|Q13555-9|KCC2G_HUMAN Isoform gamma D of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-8|KCC2G_HUMAN Isoform gamma E of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sa 0.692539 4.6867 0.00548379 -18.9762 1.6626E-20 191.78 0 0 0.692539 4.6867 9.04602E-20 176.5 0.093471 -8.92399 0.127218 49.261 0 0 1 T TESCNTTTEDEDL CK2;FHA1 Rad53p 0.059 1.6626E-20 191.78 _GSTESCNTpTTEDEDLK_ GSTESCNT(0.072)T(0.693)T(0.235)EDEDLK GS(-54.04)T(-54.04)ES(-65.42)CNT(-9.83)T(4.69)T(-4.69)EDEDLK 9 2 933.85098 0.46117 80729 0.05916 0 0 0 80729 0 0 0 3120 878 364 364 2474;2475;4309 2811;2812;4902 23244 14493 Mix4_TiO2_Reinj_1_4 3165 23241 14489 Mix4_TiO2_1_4 2764 Q13555-9;Q13555-8;Q13555-2;Q13555 Q13555-9 Q13555-9 >sp|Q13555-9|KCC2G_HUMAN Isoform gamma D of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens GN=CAMK2G;>sp|Q13555-8|KCC2G_HUMAN Isoform gamma E of Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sa 0.463404 0 0.00156718 -24.4158 1.6626E-20 191.78 0 0 0.463404 0 9.04602E-20 176.5 0.093471 -8.92399 0.127218 49.261 0 0 1 T ESCNTTTEDEDLK CK2 0.117 1.6626E-20 191.78 _GSTESCNTpTTEDEDLK_ GSTESCNT(0.073)T(0.463)T(0.463)EDEDLK GS(-76.64)T(-76.64)ES(-66.31)CNT(-8.01)T(0)T(0)EDEDLK 10 2 933.85098 0.68991 0 0 0 0 0 0 0 0 0 3121 879 336 336 1841;1842;3144 2078;2080;2081;3569;3570 16911 10181 Mix4_TiO2_Reinj_1_4 3430 16911 10181 Mix4_TiO2_Reinj_1_4 3430 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 0.999988 49.1136 0.942261 13.9461 9.79049E-09 124.39 0.320194 -1.12605 0.0255549 60.202 0.999988 49.1136 8.64559E-26 202.29 0.0605589 -7.96326 1.05743 26.128 0.49973 0 7.50688E-17 145.68 0.457688 0 1.39115E-10 134.36 2 T STESSNTTIEDED CK1;CK2 0.081 8.64559E-26 202.29 _ESTESSNpTpTIEDEDVK_ ESTESSNT(1)T(1)IEDEDVK ES(-94.85)T(-104.6)ES(-77.45)S(-45.43)NT(49.11)T(45.43)IEDEDVK 8 2 972.35576 0.82158 1104900 0.10831 152740 0 0 952150 0 0 0 3122 879 337 337 1841;1842;3144 2078;2080;2081;3569;3570 16917 10186 Mix4_InSol_Tio2_Reinj_1 3830 16851 10146 Mix4_TiO2_Reinj_1_4 3512 Q13557;Q13557-8;Q13557-11;Q13557-4;Q13557-6;Q13557-3;Q13557-5;Q13557-10;Q13557-9 Q13557 Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CAMK2D PE=1 SV=3;>sp|Q13557-8|KCC2D_HUMAN Isoform Delta 6 of Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens GN=CA 0.986027 18.66 0.904586 9.82093 5.97586E-20 182.85 0.884323 11.0547 0.0255549 60.202 0.883365 8.86861 2.17703E-33 222.33 0.0605589 -7.96326 1.05743 26.128 0.869234 8.25368 7.50688E-17 145.68 0.986027 18.66 1.39115E-10 134.36 1 T TESSNTTIEDEDV CK1;CK2;FHA1 Rad53p 0.059 2.17703E-33 222.33 _ESTESSNTpTIEDEDVKAR_ ESTESSNT(0.013)T(0.986)IEDEDVKAR ES(-58.84)T(-58.84)ES(-41.5)S(-33.16)NT(-18.66)T(18.66)IEDEDVKAR 9 2 1045.9417 0.50092 17012000 1.6677 3961400 15693 0 12065000 0 448550 521740 3123 885 611 611 6202 7084 61468 37258 Mix4_TiO2_Reinj_1_5 5592 61468 37258 Mix4_TiO2_Reinj_1_5 5592 Q13615;Q13615-2;Q13615-3 Q13615 Q13615 >sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3 PE=1 SV=3;>sp|Q13615-2|MTMR3_HUMAN Isoform FYVE-DSP1a of Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3;>sp|Q13615-3|MTMR3_HUMAN Isoform FYVE-DSP1c of Myotubularin-rela 0.280956 0 0.132372 -5.13151 0.00993202 69.053 0.280956 0 0.00522258 74.405 1 T LSRLPKTRSYDNL NEK6 0.076 0.00522258 74.405 _pTRSYDNLTTACDNTVPLASR_ T(0.281)RS(0.281)Y(0.281)DNLT(0.138)T(0.019)ACDNTVPLASR T(0)RS(0)Y(0)DNLT(-3.1)T(-11.61)ACDNT(-62.38)VPLAS(-74.4)R 1 3 779.01766 0.2505 0 0 0 0 0 0 0 0 3124 887 48 48 5125 5830 49582 30287 Mix4_InSol_TiO2_1 2503 49583 30288 Mix4_TiO2_Reinj_1_5 2403 Q13620;Q13620-1 Q13620 Q13620 >sp|Q13620|CUL4B_HUMAN Cullin-4B OS=Homo sapiens GN=CUL4B PE=1 SV=4;>sp|Q13620-1|CUL4B_HUMAN Isoform 2 of Cullin-4B OS=Homo sapiens GN=CUL4B 0.550067 1.79637 0 0 0.104584 -9.26381 7.06546E-16 163.86 0.550067 1.79637 0.000568863 94.457 0 0 1 T TDGNTSTTPPTSA 7.06546E-16 163.86 _SATDGNTSpTTPPTSAK_ SATDGNTS(0.086)T(0.55)T(0.364)PPTSAK S(-94.46)AT(-87.87)DGNT(-40.67)S(-8.06)T(1.8)T(-1.8)PPT(-34.64)S(-48.08)AK 9 2 808.34599 0.41628 45935 0 0 0 0 0 45935 0 3125 887 49 49 5125 5830 49583 30288 Mix4_TiO2_Reinj_1_5 2403 49583 30288 Mix4_TiO2_Reinj_1_5 2403 Q13620;Q13620-1 Q13620 Q13620 >sp|Q13620|CUL4B_HUMAN Cullin-4B OS=Homo sapiens GN=CUL4B PE=1 SV=4;>sp|Q13620-1|CUL4B_HUMAN Isoform 2 of Cullin-4B OS=Homo sapiens GN=CUL4B 0.882767 9.26381 0 0 0.882767 9.26381 7.06546E-16 163.86 0.36373 -1.79637 0.000568863 94.457 0 0 1 T DGNTSTTPPTSAK Proline-directed 0.05 7.06546E-16 163.86 _SATDGNTSTpTPPTSAK_ SATDGNTS(0.013)T(0.105)T(0.883)PPTSAK S(-120.95)AT(-119.85)DGNT(-45.48)S(-18.45)T(-9.26)T(9.26)PPT(-52.99)S(-77.47)AK 10 2 808.34599 -0.12212 95130 0 0 0 95130 0 0 0 3126 889 523 523 470 534 4421 2671 Mix4_TiO2_Reinj_1_5 1125 4420 2670 Mix4_TiO2_Reinj_1_3 1095 Q13627-2;Q13627;Q13627-5 Q13627-2 Q13627-2 >sp|Q13627-2|DYR1A_HUMAN Isoform 1 of Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A;>sp|Q13627|DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2;>sp|Q1362 0.655839 2.80035 0.655839 2.80035 0.00646286 61.925 0 0 0 0 1 T RARSDPTHQHRHS CK1 0.081 0.00646286 61.925 _ARSDPpTHQHR_ ARS(0.344)DPT(0.656)HQHR ARS(-2.8)DPT(2.8)HQHR 6 2 642.7833 0.48314 78460 0 0 0 78460 0 0 0 3127 900 494 494 514 580 4750 2868 Mix4_InSol_Tio2_Reinj_2 1772 4752 2870 Mix4_TiO2_Reinj_1_5 2425 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.402105 0 0.368921 0 0.0153799 66.376 0 0 0.28733 -1.3996 1.84765E-34 178.37 0 0 0.402105 0 3.32285E-07 107.57 1 T KASNTSTPTKGNT CDK1;CDK2;Polo box;Proline-directed 0.00405 1.84765E-34 178.37 _ASNTSpTPTKGNTETSASASQTNHVK_ AS(0.029)NT(0.029)S(0.094)T(0.402)PT(0.402)KGNT(0.036)ET(0.003)S(0.001)AS(0.001)AS(0.001)QT(0.001)NHVK AS(-11.39)NT(-11.39)S(-6.31)T(0)PT(0)KGNT(-10.47)ET(-21.36)S(-25.64)AS(-25.64)AS(-25.64)QT(-25.64)NHVK 6 3 867.05924 0.10796 0 0 0 0 0 0 0 0 3128 900 496 496 514 580 4750 2868 Mix4_InSol_Tio2_Reinj_2 1772 4752 2870 Mix4_TiO2_Reinj_1_5 2425 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.402105 0 0.181612 -3.07789 0.0153799 66.376 0 0 0.0276974 -11.559 1.84765E-34 178.37 0 0 0.402105 0 3.32285E-07 107.57 1 T SNTSTPTKGNTET CK1 0.081 1.84765E-34 178.37 _ASNTSpTPTKGNTETSASASQTNHVK_ AS(0.029)NT(0.029)S(0.094)T(0.402)PT(0.402)KGNT(0.036)ET(0.003)S(0.001)AS(0.001)AS(0.001)QT(0.001)NHVK AS(-11.39)NT(-11.39)S(-6.31)T(0)PT(0)KGNT(-10.47)ET(-21.36)S(-25.64)AS(-25.64)AS(-25.64)QT(-25.64)NHVK 8 3 867.05924 0.10796 0 0 0 0 0 0 0 0 3129 900 500 500 514 580 4752 2870 Mix4_TiO2_Reinj_1_5 2425 4752 2870 Mix4_TiO2_Reinj_1_5 2425 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.396589 1.3996 0.0438124 -9.25336 0.0153799 66.376 0 0 0.396589 1.3996 1.84765E-34 178.37 0 0 0.0360735 -10.4715 3.32285E-07 107.57 1 T TPTKGNTETSASA FHA KAPP 0.155 1.84765E-34 178.37 _ASNTSTPTKGNpTETSASASQTNHVK_ AS(0.001)NT(0.001)S(0.287)T(0.287)PT(0.028)KGNT(0.397)ETSASASQTNHVK AS(-28.84)NT(-28.84)S(-1.4)T(-1.4)PT(-11.56)KGNT(1.4)ET(-43.35)S(-86.97)AS(-104.94)AS(-138.7)QT(-154.59)NHVK 12 3 867.05924 -0.16213 0 0 0 0 0 0 0 0 3130 900 531 531 2740;2814 3123;3206 25932 16056 Mix4_TiO2_Reinj_1_1 2985 26912 16820 Mix4_TiO2_Reinj_1_1 3665 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.287741 0 0.247866 -1.17401 0.136124 39.391 0 0 0.287741 0 0.0122417 71.306 0 0 1 T SPSSGGTLKNDKA CK1 0.081 0.0122417 71.306 _IEHAPSPpSSGGTLK_ IEHAPS(0.137)PS(0.288)S(0.288)GGT(0.288)LK IEHAPS(-3.23)PS(0)S(0)GGT(0)LK 12 2 730.84269 0.55936 0 0 0 0 0 0 0 0 3131 900 1246 1246 2823 3215 26967 16855 Mix4_TiO2_Reinj_1_5 5523 26965 16853 Mix4_TiO2_Reinj_1_1 4959 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 1 45.3712 1 12.2808 0.0742715 44.076 1 20.0538 0.360529 20.054 1 45.3712 0.00962863 73.926 0 0 1 33.1361 0.181798 33.136 1 20.0432 0.360777 20.043 1 T MRILELTPEPDRP NEK6;Proline-directed 0.05 0.00962863 73.926 _ILELpTPEPDRPR_ ILELT(1)PEPDRPR ILELT(45.37)PEPDRPR 5 2 758.38198 -0.80926 2344300 432840 46707 0 1771800 0 28450 64498 3132 900 871 871 3809 4304 36197 22376 Mix4_TiO2_Reinj_1_1 3006 36197 22376 Mix4_TiO2_Reinj_1_1 3006 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.999309 31.7604 0.0760931 -7.42742 0.411077 21.334 0.74234 11.5853 0.696314 11.585 0.999309 31.7604 0.00325837 86.413 0 0 0.957333 20.4994 0.435486 20.499 0 0 1 T EESRPYTNKVITL CAMK2 0.042 0.00325837 86.413 _LYSSEESRPYpTNK_ LYSSEES(0.001)RPYT(0.999)NK LY(-86.41)S(-62.59)S(-46.86)EES(-31.76)RPY(-54.6)T(31.76)NK 11 2 827.36144 0.19454 1172000 0 44913 0 988150 0 138960 0 3133 900 1143 1143 4750 5396 45319 27720 Mix4_InSol_TiO2_1 5432 45321 27722 Mix4_TiO2_1_5 4383 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.547096 3.96512 0.123432 -7.34879 0.0184244 68.934 0 0 0.1088 -8.30539 0.026444 64.243 0.547096 3.96512 0.487668 47.778 0 0 1 T ATGEKQTDPSTPQ FHA KAPP 0.155 0.0184244 68.934 _QpTDPSTPQQESSKPLGGIQPSSQTIQPK_ QT(0.547)DPS(0.22)T(0.22)PQQES(0.007)S(0.007)KPLGGIQPSSQTIQPK QT(3.97)DPS(-3.97)T(-3.97)PQQES(-19.01)S(-19.01)KPLGGIQPS(-47.78)S(-47.78)QT(-47.78)IQPK 2 3 1015.4906 -0.18023 253100 0 0 0 0 0 253100 0 3134 900 1147 1147 4750 5396 45322 27723 Mix4_TiO2_Reinj_1_1 4464 45321 27722 Mix4_TiO2_1_5 4383 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.736489 6.87595 0.670356 6.73078 0.0184244 68.934 0 0 0.736489 6.87595 0.026444 64.243 0.219559 -3.96512 0.487668 47.778 0 0 1 T KQTDPSTPQQESS ERK/MAPK;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0184244 68.934 _QTDPSpTPQQESSKPLGGIQPSSQTIQPK_ QT(0.109)DPS(0.151)T(0.736)PQQES(0.003)S(0.001)KPLGGIQPSSQTIQPK QT(-8.31)DPS(-6.88)T(6.88)PQQES(-24.27)S(-29.93)KPLGGIQPS(-64.24)S(-64.24)QT(-64.24)IQPK 6 3 1015.4906 -0.83151 1578000 321240 0 0 1256700 0 0 0 3135 900 1056 1056 6124 6990 60488 36578 Mix4_TiO2_Reinj_1_5 5293 60488 36578 Mix4_TiO2_Reinj_1_5 5293 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.5 0 0.498448 0 0.422077 25.066 0 0 0.5 0 7.42836E-05 111.81 0 0 0 0 1 T GLDDSRTNTPQGV 7.42836E-05 111.81 _pTNTPQGVLPSSQLK_ T(0.5)NT(0.5)PQGVLPSSQLK T(0)NT(0)PQGVLPS(-94.98)S(-111.81)QLK 1 2 775.38472 -0.18743 227080 0 0 0 227080 0 0 0 3136 900 1058 1058 6124 6990 60488 36578 Mix4_TiO2_Reinj_1_5 5293 60488 36578 Mix4_TiO2_Reinj_1_5 5293 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.5 0 0.498448 0 0.422077 25.066 0 0 0.5 0 7.42836E-05 111.81 0 0 0 0 1 T DDSRTNTPQGVLP CAMK2;Proline-directed 0.042 7.42836E-05 111.81 _pTNTPQGVLPSSQLK_ T(0.5)NT(0.5)PQGVLPSSQLK T(0)NT(0)PQGVLPS(-94.98)S(-111.81)QLK 3 2 775.38472 -0.18743 227080 0 0 0 227080 0 0 0 3137 907 688 688 3753 4233 35467 21906 Mix4_TiO2_1_3 6154 35469 21908 Mix4_TiO2_Reinj_1_3 6939 Q14156;Q14156-2;Q14156-3 Q14156 Q14156 >sp|Q14156|EFR3A_HUMAN Protein EFR3 homolog A OS=Homo sapiens GN=EFR3A PE=1 SV=2;>sp|Q14156-2|EFR3A_HUMAN Isoform 2 of Protein EFR3 homolog A OS=Homo sapiens GN=EFR3A;>sp|Q14156-3|EFR3A_HUMAN Isoform 3 of Protein EFR3 homolog A OS=Homo sapiens GN=EFR3A 0.700812 6.61415 0.700812 6.61415 1.16553 9.8119 0 0 0.392289 -1.65714 0.000132766 97.651 0 0 0 0 1 T PYVPQVTDEDRLS CK2;FHA1 Rad53p 0.059 0.000132766 97.651 _LSVPYVPQVpTDEDRLSR_ LS(0.073)VPY(0.073)VPQVT(0.701)DEDRLS(0.153)R LS(-9.81)VPY(-9.81)VPQVT(6.61)DEDRLS(-6.61)R 10 3 685.33665 -0.15735 197630 197630 0 0 0 0 0 0 3138 909 675 675 298;2112;2113 338;339;2394;2395;2396;2397 19474 11856 Mix4_TiO2_Reinj_1_3 4777 19434 11826 Mix4_TiO2_1_3 4458 Q14164 Q14164 Q14164 >sp|Q14164|IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon OS=Homo sapiens GN=IKBKE PE=1 SV=1 0.49999 0 0.112179 -8.98021 3.25652E-09 128.49 0 0 0.49999 0 2.79955E-09 129.76 0.131439 -8.21768 0.00120077 84.243 0.188562 -3.6235 0.00552296 76.071 1 T APYPSPTRKDLLL CK2;FHA1 Rad53p 0.059 1.01376E-10 137.1 _GAQASPPPIAPYPpSPTRK_ GAQASPPPIAPYPS(0.5)PT(0.5)RK GAQAS(-112.5)PPPIAPY(-43.84)PS(0)PT(0)RK 16 2 957.97731 0.78411 515010 0 0 0 515010 0 0 0 3139 914 4366 4366 5949;6203 6784;6785;7085;7086 58671 35565 Mix4_InSol_TiO2_1 5749 58681 35587 Mix4_TiO2_Reinj_1_1 4833 Q14204 Q14204 Q14204 >sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 0.854018 8.15419 0.406687 -0.897842 0.00278452 88.632 0.0619244 -10.3689 0.627685 13.931 0.62274 2.52316 0.000126785 115.49 0.0480837 -10.475 0.604188 14.734 0.854018 8.15419 0.00238905 90.483 0.464435 1.19348 0.00454807 80.375 1 T TEKKTRTDSTSDG 0.000126785 115.49 _pTDSTSDGRPAWMR_ T(0.854)DS(0.131)T(0.014)S(0.002)DGRPAWMR T(8.15)DS(-8.15)T(-17.92)S(-27.39)DGRPAWMR 1 2 780.31905 -0.2314 2373400 0 0 0 307230 0 2066200 0 3140 914 4369 4369 5949;6203 6784;6785;7085;7086 58682 35590 Mix4_TiO2_Reinj_1_1 4886 58681 35587 Mix4_TiO2_Reinj_1_1 4833 Q14204 Q14204 Q14204 >sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens GN=DYNC1H1 PE=1 SV=5 0.538403 1.03438 0.204578 -1.59584 0.00278452 88.632 0.131964 -7.083 0.627685 13.931 0.538403 1.03438 0.000126785 115.49 0.20775 -4.11962 0.604188 14.734 0.358991 0 0.00238905 90.483 0.461775 0 0.00454807 80.375 1 T KTRTDSTSDGRPA 0.000126785 115.49 _TDSpTSDGRPAWMR_ TDS(0.424)T(0.538)S(0.037)DGRPAWMR T(-42.23)DS(-1.03)T(1.03)S(-11.6)DGRPAWMR 4 3 520.54846 -0.21429 1029400 0 0 0 1029400 0 0 0 3141 915 399 399 311;6190 354;7067;7068 61288 37120 Mix4_TiO2_1_3 2815 61289 37121 Mix4_TiO2_Reinj_1_3 3349 Q14247 Q14247 Q14247 >sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sapiens GN=CTTN PE=1 SV=2 0.762686 5.15933 0.762686 5.15933 0.627557 27.185 0.142396 -7.80073 3.63321E-12 138.1 2 T EQARAKTQTPPVS CAMK2 0.042 3.63321E-12 138.1 _pTQTPPVpSPAPQPTEER_ T(0.763)QT(0.237)PPVS(0.99)PAPQPT(0.01)EER T(5.16)QT(-5.16)PPVS(23.39)PAPQPT(-23.39)EER 1 2 947.90282 -0.69758 323090 323090 0 0 0 0 0 0 3142 915 401 401 311;6190 354;7067;7068 61290 37122 Mix4_TiO2_1_3 3099 61290 37122 Mix4_TiO2_1_3 3099 Q14247 Q14247 Q14247 >sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sapiens GN=CTTN PE=1 SV=2 0.974246 15.7821 0.974246 15.7821 1.99973E-06 115.3 0.923759 10.8337 3.63321E-12 138.1 1 T ARAKTQTPPVSPA Proline-directed 0.05 1.99973E-06 115.3 _TQpTPPVSPAPQPTEER_ T(0.026)QT(0.974)PPVSPAPQPTEER T(-15.78)QT(15.78)PPVS(-46.4)PAPQPT(-95.36)EER 3 2 907.91966 0.28285 88215 88215 0 0 0 0 0 0 3143 922 1426 1426 456 519 4247 2548 Mix4_TiO2_1_1 1003 4245 2546 Mix4_InSol_TiO2_1 1739 Q14669 Q14669 Q14669 >sp|Q14669|TRIPC_HUMAN Probable E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens GN=TRIP12 PE=1 SV=1 0.882522 9.62919 0.882522 9.62919 0.0025262 85.346 0 0 0.081892 -10.4934 0.00298743 120.38 0.796405 8.55418 0.00181989 127.59 0 0 1 T QTAPTKTSPRNAK 0.00181989 127.59 _AQTAPTKpTSPR_ AQT(0.003)APT(0.019)KT(0.883)S(0.096)PR AQT(-25.2)APT(-16.74)KT(9.63)S(-9.63)PR 8 2 619.30046 0.61392 35781 14129 0 0 0 0 21652 0 3144 923 711 711 4842;4843 5502;5503 46322 28326 Mix4_InSol_Tio2_Reinj_1 4556 46329 28334 Mix4_TiO2_Reinj_1_5 4196 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.734688 7.15792 0.0924024 -9.80858 0.000230533 111.92 0.00524406 -22.7804 0.00331901 91.004 0.160687 -6.81602 3.14349E-06 145.74 0.0202612 -15.9724 0.454445 15.972 0.244024 -1.29155 0.000209402 112.65 0.734688 7.15792 0.0258528 58.906 1 T SRRDSLTGSSDLY FHA KAPP 0.155 3.14349E-06 145.74 _RDSLpTGSSDLYKR_ RDS(0.102)LT(0.735)GS(0.141)S(0.022)DLY(0.001)KR RDS(-8.59)LT(7.16)GS(-7.16)S(-15.3)DLY(-30.41)KR 5 2 789.3696 -0.45323 274080 0 0 0 0 0 0 274080 3145 925 308 308 515 581 4765 2871 Mix4_TiO2_1_3 1805 4765 2871 Mix4_TiO2_1_3 1805 Q14677;Q14677-2 Q14677 Q14677 >sp|Q14677|EPN4_HUMAN Clathrin interactor 1 OS=Homo sapiens GN=CLINT1 PE=1 SV=1;>sp|Q14677-2|EPN4_HUMAN Isoform 2 of Clathrin interactor 1 OS=Homo sapiens GN=CLINT1 0.994865 23.8942 0.994865 23.8942 0.0200904 64.058 0 0 1 T QNASTHTPQSSVK CK1;FHA KAPP;Proline-directed 0.05 0.0200904 64.058 _ASPDQNASTHpTPQSSVK_ ASPDQNAST(0.001)HT(0.995)PQS(0.004)SVK AS(-64.06)PDQNAS(-38.14)T(-31.11)HT(23.89)PQS(-23.89)S(-38.14)VK 11 2 917.90199 -0.24334 17465 17465 0 0 0 0 0 0 3146 926 460 460 1593 1787 14647 8905 Mix4_TiO2_2_3 2953 14647 8905 Mix4_TiO2_2_3 2953 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 0.912023 10.1564 0.912023 10.1564 0.00491049 85.475 0.912023 10.1564 0.00491049 85.475 0 0 1 T KREILTTPNRYTT CDK1;CDK2;Proline-directed 0.0057 0.00491049 85.475 _EILTpTPNR_ EILT(0.088)T(0.912)PNR EILT(-10.16)T(10.16)PNR 5 2 512.24716 1.7004 217720 141180 76539 0 0 0 0 0 3147 926 428 428 4093 4661 38713 23741 Mix4_TiO2_1_3 2179 38713 23741 Mix4_TiO2_1_3 2179 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 0.998749 29.0238 0.998749 29.0238 0.00790954 61.397 0 0 0.985591 18.3508 0.0170176 57.498 0 0 0.680144 3.27647 0.888129 3.2765 1 T NKENVYTPKSAVK CDK1;ERK/MAPK;FHA KAPP;Proline-directed 0.0034 0.00790954 61.397 _NKENVYpTPK_ NKENVY(0.001)T(0.999)PK NKENVY(-29.02)T(29.02)PK 7 2 586.771 0.096476 902880 127840 0 0 763060 0 0 11987 3148 926 478 478 4256 4844 40479 24941 Mix4_TiO2_1_3 4551 40479 24941 Mix4_TiO2_1_3 4551 Q14680 Q14680 Q14680 >sp|Q14680|MELK_HUMAN Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3 1 102.583 1 102.583 5.20723E-09 118.03 0 0 0.999998 62.156 0.0160025 62.156 1 T NQCLKETPIKIPV CDK1;CDK2;NEK6;Proline-directed 0.0057 5.20723E-09 118.03 _NQCLKEpTPIKIPVNSTGTDK_ NQCLKET(1)PIKIPVNSTGTDK NQCLKET(102.58)PIKIPVNS(-102.58)T(-108.01)GT(-113.21)DK 7 3 775.0503 0.129 784770 132980 0 0 651790 0 0 0 3149 932 118 118 1906 2155 17523 10507 Mix4_TiO2_Reinj_1_4 8371 17523 10507 Mix4_TiO2_Reinj_1_4 8371 Q14739 Q14739 Q14739 >sp|Q14739|LBR_HUMAN Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 1 116.982 1 116.982 1.13014E-07 116.98 1 T EVEVKLTPLILKP FHA2 Rad53p;Proline-directed 0.05 1.13014E-07 116.98 _EVEVKLpTPLILKPFGNSISR_ EVEVKLT(1)PLILKPFGNSISR EVEVKLT(116.98)PLILKPFGNS(-116.98)IS(-116.98)R 7 3 774.09405 -1.011 87347 0 0 0 87347 0 0 0 3150 939 762 762 1924 2175 17661 10554 Mix4_TiO2_1_5 7297 17663 10556 Mix4_TiO2_Reinj_1_5 8009 Q14C86-6;Q14C86;Q14C86-2;Q14C86-5;Q14C86-4;Q14C86-3 Q14C86-6 Q14C86-6 >sp|Q14C86-6|GAPD1_HUMAN Isoform 6 of GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1;>sp|Q14C86|GAPD1_HUMAN GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1 PE=1 SV=2;>sp|Q14 0.682431 7.07459 0.682431 7.07459 1.28482 37.251 0.497748 0 0.0169044 74.952 2 T VSSRPSTPGLSVV CAMK2;ERK/MAPK;FHA2 Rad53p;Polo box;Proline-directed;WW GroupIV 0.0023175 0.0169044 74.952 _EVSSRPpSpTPGLSVVSGISATSEDIPNKIEDLR_ EVS(0.284)S(0.284)RPS(0.682)T(0.682)PGLS(0.058)VVS(0.005)GIS(0.002)AT(0.001)S(0.001)EDIPNKIEDLR EVS(-7.07)S(-7.07)RPS(7.07)T(7.07)PGLS(-13.18)VVS(-25.54)GIS(-30.94)AT(-35.33)S(-35.33)EDIPNKIEDLR 8 4 875.91939 0.33218 112490 112490 0 0 0 0 0 0 3151 943 121 121 2834 3228 27040 16892 Mix4_TiO2_Reinj_1_2 2961 27040 16892 Mix4_TiO2_Reinj_1_2 2961 Q15006 Q15006 Q15006 >sp|Q15006|TTC35_HUMAN Tetratricopeptide repeat protein 35 OS=Homo sapiens GN=TTC35 PE=1 SV=1 0.770652 5.26363 0 0 0.770652 5.26363 0.0127739 68.222 1 T QEDPTNTAARKRK 0.0127739 68.222 _ILQEDPTNpTAAR_ ILQEDPT(0.229)NT(0.771)AAR ILQEDPT(-5.26)NT(5.26)AAR 9 2 704.82704 -0.81326 22810 0 0 0 22810 0 0 0 3152 946 1331 1331 6780 7757 68732 42161 Mix4_TiO2_Reinj_1_5 6297 68730 42159 Mix4_TiO2_1_5 5191 Q15021 Q15021 Q15021 >sp|Q15021|CND1_HUMAN Condensin complex subunit 1 OS=Homo sapiens GN=NCAPD2 PE=1 SV=3 0.332872 0 0.0602453 -10.4933 1.08264E-21 171.89 0 0 0.332872 0 0.0897001 51.747 0.000105628 -39.7592 2.94862E-21 164.85 0.00718075 -21.2194 0.000277614 94.158 1 T YQPLASTASDNDF CK2;FHA1 Rad53p;NEK6 0.059 1.08264E-21 171.89 _YQPLApSTASDNDFVTPEPR_ Y(0.001)QPLAS(0.333)T(0.333)AS(0.333)DNDFVTPEPR Y(-23.82)QPLAS(0)T(0)AS(0)DNDFVT(-49.04)PEPR 7 3 729.99132 0.07662 0 0 0 0 0 0 0 0 0 3153 946 1339 1339 6780 7757 68730 42159 Mix4_TiO2_1_5 5191 68730 42159 Mix4_TiO2_1_5 5191 Q15021 Q15021 Q15021 >sp|Q15021|CND1_HUMAN Condensin complex subunit 1 OS=Homo sapiens GN=NCAPD2 PE=1 SV=3 1 110.117 1 110.117 1.08264E-21 171.89 0 0 4.14931E-06 -49.043 0.0897001 51.747 0.000595113 -32.2509 2.94862E-21 164.85 0.000124436 -39.0351 0.000277614 94.158 1 T SDNDFVTPEPRRT Proline-directed 0.05 1.08264E-21 171.89 _YQPLASTASDNDFVpTPEPR_ YQPLASTASDNDFVT(1)PEPR Y(-171.89)QPLAS(-148.41)T(-143.16)AS(-110.12)DNDFVT(110.12)PEPR 15 2 1094.4833 -0.22939 128990 0.84181 128990 0 0 0 0 0 0 3154 952 196 196 640 736 6108 3567 Mix4_TiO2_Reinj_1_2 3672 6108 3567 Mix4_TiO2_Reinj_1_2 3672 Q15131;Q15131-2;Q15131-3;Q15131-4 Q15131 Q15131 >sp|Q15131|CDK10_HUMAN Cell division protein kinase 10 OS=Homo sapiens GN=CDK10 PE=1 SV=1;>sp|Q15131-2|CDK10_HUMAN Isoform 2 of Cell division protein kinase 10 OS=Homo sapiens GN=CDK10;>sp|Q15131-3|CDK10_HUMAN Isoform 3 of Cell division protein kinase 10 O 1 65.2067 0.998337 27.7848 0.247867 27.785 0.998447 28.082 0.141371 28.082 1 65.2067 0.0144429 65.207 0 0 0 0 1 T VPVKPMTPKVVTL CDK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0144429 65.207 _AYGVPVKPM(ox)pTPK_ AYGVPVKPMT(1)PK AY(-65.21)GVPVKPMT(65.21)PK 10 2 692.34074 0.4411 162530 24012 0 0 138520 0 0 0 3155 953;954 4623;4486 4486 2552 2897 23892 14820 Mix4_InSol_TiO2_1 5380 23892 14820 Mix4_InSol_TiO2_1 5380 Q15149;Q15149-2;Q15149-3;Q15149-6;Q15149-5;Q15149-9;Q15149-8;Q15149-7;Q15149-4 Q15149;Q15149-4 Q15149-4 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC PE=1 SV=3;>sp|Q15149-2|PLEC_HUMAN Isoform Plectin-1 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-3|PLEC_HUMAN Isoform 3 of Plectin OS=Homo sapiens GN=PLEC;>sp|Q15149-6|PLEC_HUMAN Isoform Plectin-10 of 0.895466 9.33149 5.92259E-05 -42.2746 1.59648E-31 206.56 0 0 0.333296 0 6.4714E-22 174.57 0 0 0.895466 9.33149 2.14962E-58 253.21 0.0881609 -9.70475 2.18002E-15 144.29 1 T VSGSGSTAGSRTG CK1;FHA KAPP 0.081 2.14962E-58 253.21 _GYYSPYSVSGSGSpTAGSR_ GYYSPYSVSGSGS(0.104)T(0.895)AGSR GY(-253.21)Y(-253.21)S(-227.95)PY(-229.89)S(-160.17)VS(-109.78)GS(-60.16)GS(-9.33)T(9.33)AGS(-40.22)R 14 2 931.88327 0.94821 60244 0 0 0 0 0 60244 0 3156 954 19 19 6240 7129 61883 37491 Mix4_TiO2_2_1 4685 61884 37492 Mix4_TiO2_Reinj_1_1 7548 Q15149-4 Q15149-4 Q15149-4 >sp|Q15149-4|PLEC_HUMAN Isoform Plectin-11 of Plectin OS=Homo sapiens GN=PLEC 0.332428 0 0.0964396 -9.22663 0.00438645 81.132 0.332428 0 0.177168 35.662 0.106053 -8.70945 3.66289E-05 124.22 0 0 0 0 1 T GLGRKRTSSEDNL CAMK2;CHK1;CHK1/2;CK2;PKA;PKD 0.003192 3.66289E-05 124.22 _pTSSEDNLYLAVLR_ T(0.332)S(0.332)S(0.332)EDNLY(0.003)LAVLR T(0)S(0)S(0)EDNLY(-20.88)LAVLR 1 2 780.8689 0.53286 0 0 0 0 0 0 0 0 3157 958 282 282 4603;5009 5225;5226;5696;5697 43647 26764 Mix4_TiO2_1_4 7830 43647 26764 Mix4_TiO2_1_4 7830 Q15208 Q15208 Q15208 >sp|Q15208|STK38_HUMAN Serine/threonine-protein kinase 38 OS=Homo sapiens GN=STK38 PE=1 SV=1 0.499837 0 0.499837 0 5.07347E-19 155.89 0 0 0.491757 0 6.63808E-08 116 0 0 0.480737 0 0.000309417 85.757 0.448679 0 0.000448627 79.866 1 T RQLAFSTVGTPDY 5.07347E-19 155.89 _QLAFpSTVGTPDYIAPEVFM(ox)QTGYNK_ QLAFS(0.5)T(0.5)VGTPDYIAPEVFMQTGYNK QLAFS(0)T(0)VGT(-31.88)PDY(-53.54)IAPEVFMQT(-155.89)GY(-155.89)NK 6 3 958.44163 -0.54468 0 0 0 0 0 0 0 0 3158 958 285 285 4603;5009 5225;5226;5696;5697 43667 26778 Mix4_TiO2_1_6 6772 43647 26764 Mix4_TiO2_1_4 7830 Q15208 Q15208 Q15208 >sp|Q15208|STK38_HUMAN Serine/threonine-protein kinase 38 OS=Homo sapiens GN=STK38 PE=1 SV=1 0.459446 0 0.459446 0 5.07347E-19 155.89 0 0 0.333273 0 6.63808E-08 116 0 0 0.0525126 -11.5475 0.000309417 85.757 0.102456 -6.41399 0.000448627 79.866 1 T AFSTVGTPDYIAP ERK/MAPK;Proline-directed 0.0034 5.07347E-19 155.89 _QLAFpSTVGTPDYIAPEVFMQTGYNK_ QLAFS(0.459)T(0.067)VGT(0.459)PDY(0.014)IAPEVFMQTGYNK QLAFS(0)T(-8.35)VGT(0)PDY(-15.18)IAPEVFMQT(-69.5)GY(-69.5)NK 9 3 953.10999 0.15821 0 0 0 0 0 0 0 0 3159 966 733 733 3120 3544 29704 18491 Mix4_TiO2_1_1 3850 29702 18485 Mix4_InSol_Tio2_Reinj_1 5393 Q15418 Q15418 Q15418 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.954292 13.8086 0.954292 13.8086 0.0692488 62.288 0.498964 0 0.136026 48.505 0.186669 -6.39188 0.0693202 64.488 0.498964 0 0.0386639 91.839 1 T VRKLPSTTL____ NEK6 0.076 0.0386639 91.839 _KLPSpTTL_ KLPS(0.04)T(0.954)T(0.006)L KLPS(-13.81)T(13.81)T(-22.01)L 5 2 420.21734 -0.01844 88364 88364 0 0 0 0 0 0 3160 966 359 359 6140 7008;7009 60612 36702 Mix4_TiO2_1_3 8281 60618 36713 Mix4_TiO2_Reinj_1_3 5411 Q15418 Q15418 Q15418 >sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2 0.844694 7.46822 0.844694 7.46822 3.19627E-06 103.9 0 0 0.999771 34.1554 2.71278E-10 127.83 0 0 0.821238 6.9111 1.817E-06 110.03 0.843324 7.30998 4.21967E-05 98.179 1 T TEFTSRTPKDSPG CDK1;CK2;FHA1 Rad53p;Proline-directed 0.0057 2.8559E-10 127.35 _pTPKDSPGIPPSAGAHQLFR_ T(0.845)PKDS(0.151)PGIPPS(0.004)AGAHQLFR T(7.47)PKDS(-7.47)PGIPPS(-23.25)AGAHQLFR 1 3 686.00524 -0.36198 3684000 172390 0 0 0 0 729180 2782400 3161 977 309 309 2710;2711 3087;3088 25590 15814 Mix4_TiO2_Reinj_1_5 3481 25570 15804 Mix4_TiO2_1_5 3181 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.359437 0 0.0228554 -15.7008 4.36025E-07 155.16 1.4493E-05 -47.9285 0.0662534 47.929 0.359437 0 1.03041E-05 135.36 0.0154215 -15.485 4.58852E-06 140.71 0.0404843 -11.3506 0.00222631 91.246 1 T KQNKICTEQSNSP FHA KAPP 0.155 4.36025E-07 155.16 _ICpTEQSNSPPPIRR_ ICT(0.359)EQS(0.359)NS(0.281)PPPIRR ICT(0)EQS(0)NS(-1.07)PPPIRR 3 3 578.93795 0.0063683 0 0 0 0 0 0 0 0 3162 977 577 577 4410;4434 5018;5044 42174 25977 Mix4_TiO2_Reinj_1_5 3424 42175 25978 Mix4_TiO2_Reinj_1_5 3448 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.867165 8.40189 0.364866 -0.918655 0.986643 6.8946 0.867165 8.40189 0.016916 66.734 0 0 0 0 1 T PRPRPATSTPDLA CAMK2;PKA/AKT 0.001764 0.016916 66.734 _PRPApTSTPDLASHR_ PRPAT(0.867)S(0.125)T(0.007)PDLASHR PRPAT(8.4)S(-8.4)T(-20.72)PDLAS(-36.39)HR 5 3 529.25427 0.12015 628100 0 0 0 628100 0 0 0 3163 977 579 579 4410;4434 5018;5044 42172 25975 Mix4_TiO2_1_5 3015 42175 25978 Mix4_TiO2_Reinj_1_5 3448 Q15678 Q15678 Q15678 >sp|Q15678|PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens GN=PTPN14 PE=1 SV=2 0.450816 0.918655 0.450816 0.918655 0.986643 6.8946 0.13316 -8.07582 0.016916 66.734 0 0 0 0 1 T PRPATSTPDLASH FHA2 Rad53p;Polo box;Proline-directed 0.00405 0.016916 66.734 _PRPATSpTPDLASHR_ PRPAT(0.365)S(0.092)T(0.451)PDLAS(0.092)HR PRPAT(-0.92)S(-6.89)T(0.92)PDLAS(-6.89)HR 7 3 529.25427 -0.055988 0 0 0 0 0 0 0 0 3164 983 32 32 2724 3104 25728 15899 Mix4_TiO2_1_5 4470 25727 15897 Mix4_TiO2_1_4 4459 Q15831 Q15831 Q15831 >sp|Q15831|STK11_HUMAN Serine/threonine-protein kinase 11 OS=Homo sapiens GN=STK11 PE=1 SV=1 0.5 0 0.5 0 3.61196E-06 156.38 0.0427648 -13.4993 0.00250252 123.37 0.0939176 -9.84421 0.00290115 120.91 0.5 0 0.00311299 79.363 0.0707168 -11.1863 0.00180678 93.355 1 T IHRIDSTEVIYQP FHA2 Rad53p 0.114 3.61196E-06 156.38 _IDpSTEVIYQPR_ IDS(0.5)T(0.5)EVIYQPR IDS(0)T(0)EVIY(-66.66)QPR 4 2 700.82651 -0.23842 44445 28298 0 0 0 0 16147 0 3165 987;988 774;780 780 1552;6251 1742;1743;7142 62047 37605 Mix4_TiO2_1_3 8009 62071 37651 Mix4_TiO2_Reinj_1_6 7329 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.362205 0 0.362205 0 1.77615E-24 160.85 0.353275 0 8.6153E-08 116.42 0.360862 0 3.22849E-25 173.21 0.315107 0 0.0977881 53.911 0.359739 0 9.09734E-07 100.23 0.332812 0 0.0016674 78.428 1 T YGDRTSTFCGTPE CAMK2 0.042 3.22849E-25 173.21 _TpSTFCGTPEFLAPEVLTDTSYTR_ T(0.276)S(0.362)T(0.362)FCGTPEFLAPEVLTDTSYTR T(-1.19)S(0)T(0)FCGT(-58.29)PEFLAPEVLT(-127.46)DT(-127.46)S(-127.46)Y(-127.46)T(-127.46)R 3 2 1337.0931 -0.17982 0 0 0 0 0 0 0 0 3166 987;988 778;784 784 1552;6251 1742;1743;7142 62045 37601 Mix4_TiO2_1_1 7267 62071 37651 Mix4_TiO2_Reinj_1_6 7329 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.509648 4.64048 0.509648 4.64048 1.77615E-24 160.85 0.0644325 -6.84434 8.6153E-08 116.42 0.367233 2.4082 3.22849E-25 173.21 0.349899 0.605001 0.0977881 53.911 0.270531 0.728308 9.09734E-07 100.23 0.25 0 0.0016674 78.428 1 T TSTFCGTPEFLAP Proline-directed 0.05 3.22849E-25 173.21 _TSTFCGpTPEFLAPEVLTDTSYTR_ T(0.14)S(0.175)T(0.175)FCGT(0.51)PEFLAPEVLTDTSYTR T(-5.61)S(-4.64)T(-4.64)FCGT(4.64)PEFLAPEVLT(-112.96)DT(-125.68)S(-132.25)Y(-132.25)T(-132.25)R 7 3 891.73118 -0.083743 151030 151030 0 0 0 0 0 0 3167 987;988 527;533 533 3486 3935;3936 32884 20379 Mix4_InSol_TiO2_2 4437 32887 20383 Mix4_TiO2_1_5 4833 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.287059 0.593679 2.026E-06 -56.2147 3.90247E-11 124.2 0 0 0.00896966 -20.4644 0.00632134 73.083 0.287059 0.593679 3.49282E-11 125.59 9.58461E-05 -40.0989 1.93698E-07 114.29 1 T RLIPNATGTGTFS 5.06626E-24 164.47 _LIPNApTGTGTFSPGASPGSEAR_ LIPNAT(0.287)GT(0.25)GT(0.25)FS(0.164)PGAS(0.024)PGS(0.024)EAR LIPNAT(0.59)GT(-0.59)GT(-0.59)FS(-2.43)PGAS(-10.77)PGS(-10.77)EAR 6 2 1084.5046 -0.18593 0 0 0 0 0 0 0 0 0 3168 987;988 531;537 537 3486 3935;3936 32885 20380 Mix4_InSol_Tio2_Reinj_1 5876 32887 20383 Mix4_TiO2_1_5 4833 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.568776 1.25287 0.141565 -7.8592 3.90247E-11 124.2 0 0 0.154012 -7.39252 2.74427E-18 156.27 0.250382 -0.593679 3.49282E-11 125.59 0.568776 1.25287 1.93698E-07 114.29 1 T NATGTGTFSPGAS 5.06626E-24 164.47 _LIPNATGTGpTFSPGASPGSEAR_ LIPNATGTGT(0.569)FS(0.426)PGAS(0.005)PGSEAR LIPNAT(-65.23)GT(-34.96)GT(1.25)FS(-1.25)PGAS(-20.74)PGS(-50.36)EAR 10 2 1084.5046 0.0031942 264700 0.67915 0 0 0 0 0 0 264700 3169 987;988 106;112 112 4931 5607 47428 28964 Mix4_TiO2_Reinj_1_6 6808 47427 28962 Mix4_TiO2_Reinj_1_6 6814 Q16512;Q16512-3;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-3|PKN1_HUMAN Isoform 3 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase 0.697382 4.31779 0.697382 4.31779 4.02231E-10 119.03 0.0111792 -14.726 0.00572419 90.06 1 T LPDPAATHDGPQS 4.02231E-10 119.03 _RLDLLHQQLQELHAHVVLPDPAApTHDGPQSPGAGGPTCSATNLSR_ RLDLLHQQLQELHAHVVLPDPAAT(0.697)HDGPQS(0.258)PGAGGPT(0.028)CS(0.011)AT(0.005)NLS(0.001)R RLDLLHQQLQELHAHVVLPDPAAT(4.32)HDGPQS(-4.32)PGAGGPT(-13.91)CS(-18.16)AT(-21.88)NLS(-28.11)R 24 6 807.89823 -0.32866 203900 0 0 0 203900 0 0 0 3170 987;988 914;920 920 5951;5952 6788;6789 58742 35642 Mix4_TiO2_1_5 6607 58801 35700 Mix4_TiO2_1_5 6248 Q16512;Q16512-2 Q16512;Q16512-2 Q16512-2 >sp|Q16512|PKN1_HUMAN Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 PE=1 SV=2;>sp|Q16512-2|PKN1_HUMAN Isoform 2 of Serine/threonine-protein kinase N1 OS=Homo sapiens GN=PKN1 0.546003 0.803431 0.546003 0.803431 5.6501E-63 243.38 0.055694 -12.2913 1.05333E-32 190.16 0.499615 0 5.95251E-39 206.92 0.124161 -8.48273 1.1472E-16 146.74 0.0611275 -11.8637 8.89738E-18 145.78 0.00824081 -20.8042 0.0667466 57.384 1 T FTGEAPTLSPPRD 5.6501E-63 243.38 _TDVSNFDEEFTGEAPpTLSPPR_ TDVSNFDEEFTGEAPT(0.546)LS(0.454)PPR T(-45.67)DVS(-45.67)NFDEEFT(-34.83)GEAPT(0.8)LS(-0.8)PPR 16 4 598.01124 0.05926 44497 44497 0 0 0 0 0 0 3171 989 527 527 279 319 2629 1644 Mix4_InSol_Tio2_Reinj_1 7699 2631 1647 Mix4_TiO2_1_5 6337 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.527609 1.42594 0.0696784 -10.9317 2.18381E-12 132.32 0.0168855 -15.6777 0.00907723 73.372 0.00263937 -23.9736 3.95704E-05 96.116 0.319293 0 0.0235501 63.225 0.527609 1.42594 0.0167541 68.014 1 T VRRAIPTVNHSGT 2.18381E-12 132.32 _AIPpTVNHSGTFSPQAPVPTTVPVVDVR_ AIPT(0.528)VNHS(0.38)GT(0.054)FS(0.038)PQAPVPTTVPVVDVR AIPT(1.43)VNHS(-1.43)GT(-9.9)FS(-11.37)PQAPVPT(-68.01)T(-68.01)VPVVDVR 4 3 956.15481 0.36369 212000 0 0 0 0 0 0 212000 3172 989 533 533 279 319 2628 1643 Mix4_InSol_TiO2_1 7761 2631 1647 Mix4_TiO2_1_5 6337 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.319293 0 0.189154 -4.77081 2.18381E-12 132.32 0.30039 -3.17598 0.00907723 73.372 0.189177 -5.41991 3.95704E-05 96.116 0.319293 0 0.0235501 63.225 0.0539934 -9.89971 0.0167541 68.014 1 T TVNHSGTFSPQAP 2.18381E-12 132.32 _AIPpTVNHSGTFSPQAPVPTTVPVVDVR_ AIPT(0.319)VNHS(0.319)GT(0.319)FS(0.042)PQAPVPTTVPVVDVR AIPT(0)VNHS(0)GT(0)FS(-8.8)PQAPVPT(-56.59)T(-60.26)VPVVDVR 10 3 956.15481 0.24496 0 0 0 0 0 0 0 0 3173 989 364 364 588;589;5384 675;676;677;6127 5604 3329 Mix4_TiO2_1_5 6361 5594 3326 Mix4_TiO2_Reinj_1_5 6730 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.279442 0 0.279442 0 0.0155781 61.906 0.00158349 -27.593 0.0294092 59.454 0.278491 0 0.000691393 94.776 0.108228 -7.15096 0.000450729 85.344 0.0766514 -7.54309 0.603599 35.383 1 T GWSPSETRSSFMS FHA KAPP 0.155 0.000691393 94.776 _ATSVALPGWSPSEpTRSSFMSR_ ATSVALPGWS(0.014)PS(0.103)ET(0.279)RS(0.279)S(0.279)FMS(0.045)R AT(-47.97)S(-47.97)VALPGWS(-13.1)PS(-4.34)ET(0)RS(0)S(0)FMS(-7.92)R 14 3 778.69099 0.029947 0 0 0 0 0 0 0 0 3174 989 951 951 1464;2404;2405 1646;2725;2726 22451 14029 Mix4_TiO2_Reinj_1_5 7091 13692 8365 Mix4_TiO2_2_2 6376 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.37834 0 0.0589846 -11.4255 6.89928E-35 191.07 9.32017E-05 -40.3038 3.89764E-45 207.33 0.37834 0 3.48587E-18 152.4 0.019565 -16.8225 1.89448 16.823 0.00533412 -22.6692 6.12632E-05 95.401 0.0114429 -19.3123 0.699488 38.207 1 T NFDDEFTSEAPIL FHA KAPP 0.155 3.89764E-45 207.33 _GREDVSNFDDEFpTSEAPILTPPREPR_ GREDVS(0.205)NFDDEFT(0.378)S(0.378)EAPILT(0.038)PPREPR GREDVS(-2.66)NFDDEFT(0)S(0)EAPILT(-9.96)PPREPR 13 2 1527.6957 0.85911 0 0 0 0 0 0 0 0 3175 989 958 958 1464;2404;2405 1646;2725;2726 22446 14018 Mix4_TiO2_Reinj_1_3 7117 13692 8365 Mix4_TiO2_2_2 6376 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 1 90.697 1 77.0994 6.89928E-35 191.07 1 101.986 3.89764E-45 207.33 1 90.697 3.48587E-18 152.4 0.941305 16.8225 1.89448 16.823 0.999879 39.3624 6.12632E-05 95.401 0.997881 30.2457 0.699488 38.207 1 T SEAPILTPPREPR CDK1;CDK2;Proline-directed 0.0057 3.89764E-45 207.33 _GREDVSNFDDEFTSEAPILpTPPREPR_ GREDVSNFDDEFTSEAPILT(1)PPREPR GREDVS(-151.97)NFDDEFT(-97.95)S(-90.7)EAPILT(90.7)PPREPR 20 4 764.35147 -0.30226 53994000 7454200 772430 0 41674000 44367 2120400 1929300 3176 989 304 304 2797 3187 26809 16769 Mix4_TiO2_Reinj_1_5 8332 26810 16771 Mix4_TiO2_Reinj_1_5 8333 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.653257 2.7511 0.491457 0 0.442484 32.691 0.653257 2.7511 5.12606E-11 136.29 1 T LVAASPTLSPRQS 5.12606E-11 136.29 _IIIEELSLVAASPpTLSPR_ IIIEELSLVAAS(0.347)PT(0.653)LSPR IIIEELS(-49.63)LVAAS(-2.75)PT(2.75)LS(-45.24)PR 14 2 995.03703 0.39893 475060 0 0 0 475060 0 0 0 3177 989 816 816 6252 7143 62124 37686 Mix4_TiO2_Reinj_1_3 8777 62128 37694 Mix4_TiO2_Reinj_1_5 8566 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.358442 0 0.332934 0 3.54726E-12 135.51 0.344575 0 8.02328E-07 102.34 0.358442 0 2.30988E-17 146.73 0 0 0.317036 0 0.000509078 83.595 0.321195 0 0.216594 44.418 1 T YGDRTSTFCGTPE CAMK2 0.042 2.30988E-17 146.73 _TpSTFCGTPEFLAPEVLTETSYTR_ T(0.282)S(0.358)T(0.358)FCGT(0.002)PEFLAPEVLTETSYTR T(-1.05)S(0)T(0)FCGT(-23.7)PEFLAPEVLT(-103.54)ET(-103.54)S(-103.54)Y(-103.54)T(-103.54)R 3 2 1344.101 0.25725 0 0 0 0 0 0 0 0 3178 989 820 820 6252 7143 62110 37663 Mix4_TiO2_1_1 7328 62128 37694 Mix4_TiO2_Reinj_1_5 8566 Q16513 Q16513 Q16513 >sp|Q16513|PKN2_HUMAN Serine/threonine-protein kinase N2 OS=Homo sapiens GN=PKN2 PE=1 SV=1 0.711471 8.69088 0.711471 8.69088 3.54726E-12 135.51 0.0362724 -9.77707 8.02328E-07 102.34 0.675936 7.63143 2.30988E-17 146.73 0 0 0.25 0 0.000509078 83.595 0.0675008 -6.77459 0.216594 44.418 1 T TSTFCGTPEFLAP Proline-directed 0.05 2.30988E-17 146.73 _TSTFCGpTPEFLAPEVLTETSYTR_ T(0.096)S(0.096)T(0.096)FCGT(0.711)PEFLAPEVLTETSYTR T(-8.69)S(-8.69)T(-8.69)FCGT(8.69)PEFLAPEVLT(-73.32)ET(-85.27)S(-86.81)Y(-86.81)T(-86.81)R 7 3 896.40306 0.40556 261570 106060 0 0 155500 0 0 0 3179 992 526 526 4364;4972 4963;5654 47979 29332 Mix4_InSol_TiO2_1 7421 41400 25456 Mix4_TiO2_1_3 6329 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.978244 16.5287 0.5 0 4.7206E-22 196.53 0 0 0.232012 -5.19845 9.69685E-12 160.78 0 0 0.978244 16.5287 9.69685E-12 160.78 0.652505 2.73634 3.25025E-09 142.78 1 T GPGDSPTFPRFRA 4.7206E-22 196.53 _RNVFEVGPGDSPpTFPR_ RNVFEVGPGDS(0.022)PT(0.978)FPR RNVFEVGPGDS(-16.53)PT(16.53)FPR 13 3 618.956 0.15386 252940 78486 0 0 0 0 60717 113740 3180 992 702 702 6132 6999;7000 60565 36615 Mix4_TiO2_Reinj_1_5 9031 60564 36614 Mix4_TiO2_Reinj_1_3 9263 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.660137 0 0.476294 0 2.07485E-32 177.38 0.445362 0 4.12675E-11 123.44 0.660137 0 4.19571E-07 109.84 0 0 2 T ICFSLKTPDSPPT CK1;FHA KAPP;Proline-directed 0.05 4.19571E-07 109.84 _pTPDSPPpTPAPLLLDLGIPVGQR_ T(0.66)PDS(0.66)PPT(0.68)PAPLLLDLGIPVGQR T(0)PDS(0)PPT(0.26)PAPLLLDLGIPVGQR 1 3 805.39712 -0.07563 348410 0 0 0 348410 0 0 0 3181 992 708 708 6132 6999;7000 60564 36614 Mix4_TiO2_Reinj_1_3 9263 60564 36614 Mix4_TiO2_Reinj_1_3 9263 Q16584 Q16584 Q16584 >sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1 0.98898 16.5196 0.164177 -6.36416 2.07485E-32 177.38 0.109276 -6.10189 4.12675E-11 123.44 0.98898 16.5196 4.19571E-07 109.84 0 0 2 T TPDSPPTPAPLLL CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 4.19571E-07 109.84 _pTPDSPPpTPAPLLLDLGIPVGQR_ T(0.506)PDS(0.506)PPT(0.989)PAPLLLDLGIPVGQR T(0)PDS(0)PPT(16.52)PAPLLLDLGIPVGQR 7 3 805.39712 0.071034 348410 0 0 0 348410 0 0 0 3182 994 25 25 2492;4902 2831;2832;5574 23450 14590 Mix4_TiO2_Reinj_1_2 6956 23447 14585 Mix4_TiO2_1_4 7449 Q16637;Q16637-3;Q16637-2;Q16637-4 Q16637 Q16637 >sp|Q16637|SMN_HUMAN Survival motor neuron protein OS=Homo sapiens GN=SMN1 PE=1 SV=1;>sp|Q16637-3|SMN_HUMAN Isoform Iso7-SMN of Survival motor neuron protein OS=Homo sapiens GN=SMN1;>sp|Q16637-2|SMN_HUMAN Isoform Iso5-SMN of Survival motor neuron protein O 0.903462 7.21307 0.726543 4.24533 6.4239E-39 227.22 0.903462 7.21307 1.09419E-38 222.57 0 0 2 T VLFRRGTGQSDDS CAMK2;CHK1;CHK1/2;FHA KAPP;PKA;PKD 0.003192 1.2827E-47 236.85 _GpTGQSDDpSDIWDDTALIK_ GT(0.903)GQS(0.492)DDS(0.604)DIWDDTALIK GT(7.21)GQS(-1.08)DDS(1.08)DIWDDT(-40.43)ALIK 2 3 699.60809 0.25329 48613 19645 0 0 28968 0 0 0 3183 996 389 389 351 399;400 3285 1977 Mix4_TiO2_Reinj_1_5 5585 3285 1977 Mix4_TiO2_Reinj_1_5 5585 Q16659 Q16659 Q16659 >sp|Q16659|MK06_HUMAN Mitogen-activated protein kinase 6 OS=Homo sapiens GN=MAPK6 PE=1 SV=1 1 136.85 1 115.736 1.69152E-06 115.74 1 136.85 4.11887E-10 136.85 2 T RALSDVTDEEEVQ CK1;CK2 0.081 4.11887E-10 136.85 _ALpSDVpTDEEEVQVDPR_ ALS(1)DVT(1)DEEEVQVDPR ALS(136.85)DVT(136.85)DEEEVQVDPR 6 2 981.39248 0.19645 612500 80943 0 0 531550 0 0 0 3184 1002 165 165 1473;4854;5285;5286 1656;5517;5518;6014;6017 51299 31420 Mix4_TiO2_Reinj_1_5 3741 13734 8391 Mix4_TiO2_Reinj_1_3 3612 Q1KMD3 Q1KMD3 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens GN=HNRNPUL2 PE=1 SV=1 0.960136 14.0788 0.0164651 -17.7617 2.00339E-17 148.05 0.0150381 -18.1374 0.0845367 54.341 0.960136 14.0788 4.9392E-24 164.76 0 0 0 0 0 0 1 T ERSGDETPGSEVP FHA KAPP;Proline-directed 0.05 4.9392E-24 164.76 _SGDEpTPGSEVPGDKAAEEQGDDQDSEK_ S(0.038)GDET(0.96)PGS(0.002)EVPGDKAAEEQGDDQDSEK S(-14.08)GDET(14.08)PGS(-26.15)EVPGDKAAEEQGDDQDS(-107.03)EK 5 3 953.04376 -0.016908 236920 0.025524 0 0 0 236920 0 0 0 3185 1007 389 389 242 278 2428 1549 Mix4_TiO2_Reinj_1_5 7056 2427 1548 Mix4_TiO2_Reinj_1_4 7074 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 1 140.051 1 116.567 6.75032E-16 140.05 1 124.574 7.09011E-16 139.21 1 140.051 1.25223E-21 159.55 0 0 1 82.559 0.000319006 90.087 1 148.824 3.18798E-16 148.82 1 T PIQPALTPRKRAT CDK1;CDK2;Proline-directed 0.0057 1.25223E-21 159.55 _AGQTQPNPGILPIQPALpTPR_ AGQTQPNPGILPIQPALT(1)PR AGQT(-140.05)QPNPGILPIQPALT(140.05)PR 18 3 717.04369 0.15253 16924000 475.7 3540600 1444800 0 10259000 0 862740 816760 3186 1007 640 640 2836;4916 3230;5589 27085 16948 Mix4_TiO2_Reinj_2_1 4840 27080 16940 Mix4_TiO2_Reinj_1_5 7639 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.778271 7.98892 0.475805 2.50989 3.44873E-20 179.41 0.0888074 -9.45136 8.90566E-18 175.6 0.619039 3.95436 3.57167E-26 203.31 0.778271 7.98892 0.0515112 56.334 0.382326 -1.49657 3.35294E-09 128.23 0.489025 0 3.52237E-06 111.42 1 T RILSDVTHSAVFG CK1;FHA KAPP 0.081 3.57167E-26 203.31 _ILSDVpTHSAVFGVPASK_ ILS(0.124)DVT(0.778)HS(0.098)AVFGVPASK ILS(-7.99)DVT(7.99)HS(-9)AVFGVPAS(-56.33)K 6 3 603.30451 0.23097 597680 0 0 0 581810 15874 0 0 3187 1007 674 674 5128;5398 5833;5834;6143;6144 52582 32150 Mix4_InSol_TiO2_1 1436 52582 32150 Mix4_InSol_TiO2_1 1436 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.999556 35.7537 0.873987 7.07684 0.0268476 58.66 0.017065 -17.1995 0.39631 17.199 0.766968 5.18199 0.00694284 69.94 0.999556 35.7537 0.000296126 109.67 0.999043 31.3824 0.000297962 109.6 2 T SKSATTTPSGSPR Proline-directed 0.05 0.000296126 109.67 _SKSATTpTPSGpSPR_ SKSATTT(1)PS(0.001)GS(0.999)PR S(-76.54)KS(-59.88)AT(-43.86)T(-35.75)T(35.75)PS(-29.06)GS(29.06)PR 7 2 718.79455 0.01189 1407700 133790 0 0 537460 0 339740 396720 3188 1007 653 653 5799 6605 57113 34836 Mix4_TiO2_Reinj_1_5 7054 57113 34836 Mix4_TiO2_Reinj_1_5 7054 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.624128 2.20234 0.5 0 0.0183783 66.131 0 0 0.624128 2.20234 5.48738E-26 206.77 1 T VPASKSTQLLQAA CK1;FHA2 Rad53p 0.081 5.48738E-26 206.77 _SpTQLLQAAAAEASLNK_ S(0.376)T(0.624)QLLQAAAAEASLNK S(-2.2)T(2.2)QLLQAAAAEAS(-206.77)LNK 2 2 848.41929 0.21713 750710 8.0554 38919 0 0 711790 0 0 0 3189 1007 620 620 6418;6419 7340;7341;7342;7343 64759 39716 Mix4_InSol_Tio2_Reinj_1 3997 64768 39754 Mix4_TiO2_Reinj_1_5 3877 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.997528 24.7726 0.989835 22.6072 0.0313194 54.175 0.87786 8.44378 0.443562 14.979 0.779026 1.83388 0.71845 1.8339 0.113965 -12.1945 0.426591 15.776 0.990826 21.1362 0.0307815 54.335 0.997528 24.7726 0.0106764 60.755 2 T QKVGSLTPPSSPK FHA KAPP;Proline-directed 0.05 0.0106764 60.755 _VGSLpTPPpSSPK_ VGSLT(0.998)PPS(0.613)S(0.389)PK VGS(-34.48)LT(24.77)PPS(1.99)S(-1.99)PK 5 2 615.26437 0.18328 41288000 4869100 332610 0 14735000 0 13458000 7893500 3190 1007 605 605 6572 7521 66583 40845 Mix4_InSol_Tio2_Reinj_5 1533 66596 40874 Mix4_TiO2_Reinj_1_5 3186 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.5 0 0.0258925 -15.7543 4.9299E-05 118.86 0.0314705 -14.8821 4.38505E-05 121.17 0.021646 -16.5512 5.99101E-09 163.25 0.0282937 -15.3584 0.0659005 48.025 0.5 0 2.09254E-06 149.4 0.5 0 4.70332E-06 140.31 1 T QQPKVQTTPPPAV 5.99101E-09 163.25 _VQpTTPPPAVQGQK_ VQT(0.5)T(0.5)PPPAVQGQK VQT(0)T(0)PPPAVQGQK 3 2 715.8556 -0.22486 260700 12.202 0 0 0 0 0 4050.2 256650 3191 1007 606 606 6572 7521 66570 40826 Mix4_InSol_TiO2_1 3435 66596 40874 Mix4_TiO2_Reinj_1_5 3186 Q2M2I8;Q2M2I8-2 Q2M2I8 Q2M2I8 >sp|Q2M2I8|AAK1_HUMAN AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 PE=1 SV=3;>sp|Q2M2I8-2|AAK1_HUMAN Isoform 2 of AP2-associated protein kinase 1 OS=Homo sapiens GN=AAK1 0.999758 36.1591 0.998611 28.5659 4.9299E-05 118.86 0.996736 24.8478 4.38505E-05 121.17 0.99857 28.4396 5.99101E-09 163.25 0.971706 15.3584 0.0659005 48.025 0.999758 36.1591 2.09254E-06 149.4 0.980879 17.1011 4.70332E-06 140.31 1 T QPKVQTTPPPAVQ Proline-directed 0.05 5.99101E-09 163.25 _VQTpTPPPAVQGQK_ VQTT(1)PPPAVQGQK VQT(-36.16)T(36.16)PPPAVQGQK 4 2 715.8556 -0.11364 23795000 1113.7 3607700 809810 0 11562000 37290 4374400 3403500 3192 1014 78 78 5978 6818 59022 35810 Mix4_TiO2_Reinj_1_6 5401 59022 35810 Mix4_TiO2_Reinj_1_6 5401 Q3MHD2-2;Q3MHD2 Q3MHD2-2 Q3MHD2-2 >sp|Q3MHD2-2|LSM12_HUMAN Isoform 2 of Protein LSM12 homolog OS=Homo sapiens GN=LSM12;>sp|Q3MHD2|LSM12_HUMAN Protein LSM12 homolog OS=Homo sapiens GN=LSM12 PE=1 SV=2 0.992973 21.5017 0.906448 9.8629 7.44919E-11 156.58 0.980257 16.9597 0.0231565 60.824 0.992973 21.5017 4.31419E-16 190 1 T INDRTETPPPLAS CAMK2;Proline-directed 0.042 4.31419E-16 190 _TEpTPPPLASLNVSK_ T(0.007)ET(0.993)PPPLASLNVSK T(-21.5)ET(21.5)PPPLAS(-150.91)LNVS(-181.29)K 3 2 767.38165 0.065486 725870 228750 33012 0 464110 0 0 0 3193 1030 17 17 5627 6412 54956 33650 Mix4_TiO2_Reinj_1_6 2496 54957 33652 Mix4_TiO2_Reinj_1_6 2517 Q5BJD5;Q5BJD5-2 Q5BJD5 Q5BJD5 >sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens GN=TMEM41B PE=1 SV=1;>sp|Q5BJD5-2|TM41B_HUMAN Isoform 2 of Transmembrane protein 41B OS=Homo sapiens GN=TMEM41B 0.499983 0 0 0 0 0 0.499983 0 0.0140581 66.663 0.233351 -5.11376 0.899716 22.193 0.499959 0 0.181945 40.855 1 T QLGAHHTTPVGDG 0.0140581 66.663 _SQLGAHHpTTPVGDGAAGTR_ SQLGAHHT(0.5)T(0.5)PVGDGAAGTR S(-43.84)QLGAHHT(0)T(0)PVGDGAAGT(-46.06)R 8 3 638.29356 -0.18548 356870 0 0 0 294110 0 0 62762 3194 1030 18 18 5627 6412 54953 33647 Mix4_InSol_TiO2_1 3316 54957 33652 Mix4_TiO2_Reinj_1_6 2517 Q5BJD5;Q5BJD5-2 Q5BJD5 Q5BJD5 >sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens GN=TMEM41B PE=1 SV=1;>sp|Q5BJD5-2|TM41B_HUMAN Isoform 2 of Transmembrane protein 41B OS=Homo sapiens GN=TMEM41B 0.757506 5.11376 0 0 0 0 0.499983 0 0.0140581 66.663 0.757506 5.11376 0.899716 22.193 0.499959 0 0.181945 40.855 1 T LGAHHTTPVGDGA Proline-directed 0.05 0.0140581 66.663 _SQLGAHHTpTPVGDGAAGTR_ S(0.005)QLGAHHT(0.233)T(0.758)PVGDGAAGT(0.005)R S(-22.19)QLGAHHT(-5.11)T(5.11)PVGDGAAGT(-22.19)R 9 3 638.29356 0.11517 422580 0 0 0 294110 0 65706 62762 3195 1031 272 272 2908;2909;5591 3312;3313;6372 27827 17329 Mix4_InSol_Tio2_Reinj_1 3661 54687 33483 Mix4_TiO2_Reinj_1_3 1649 Q5BKZ1 Q5BKZ1 Q5BKZ1 >sp|Q5BKZ1|ZN326_HUMAN Zinc finger protein 326 OS=Homo sapiens GN=ZNF326 PE=1 SV=2 0.893237 10.1779 0.233079 -5.11042 0.105733 38.351 0.545582 0.824661 5.09184E-05 113.84 0.282188 -4.04944 0.128937 38.645 0.893237 10.1779 0.379521 23.025 1 T SLSKSPTKTDPKN CHK1;CK2;FHA1 Rad53p;PKD 0.020748 5.09184E-05 113.84 _ISLSKSPpTKTDPK_ IS(0.004)LS(0.004)KS(0.086)PT(0.893)KT(0.012)DPK IS(-23.03)LS(-23.03)KS(-10.18)PT(10.18)KT(-18.67)DPK 8 2 741.38419 0.36797 749430 0 0 0 712600 0 0 36827 3196 1031 274 274 2909;5591 3313;6372 27826 17328 Mix4_InSol_TiO2_1 3652 54687 33483 Mix4_TiO2_Reinj_1_3 1649 Q5BKZ1 Q5BKZ1 Q5BKZ1 >sp|Q5BKZ1|ZN326_HUMAN Zinc finger protein 326 OS=Homo sapiens GN=ZNF326 PE=1 SV=2 0.71694 4.04944 0.0907205 -8.33636 0.36682 23.816 0.000831745 -28.1687 5.09184E-05 113.84 0.71694 4.04944 0.128937 38.645 0.0121229 -18.6736 0.379521 23.025 1 T SKSPTKTDPKNEE 5.09184E-05 113.84 _ISLSKSPTKpTDPK_ ISLSKS(0.001)PT(0.282)KT(0.717)DPK IS(-38.64)LS(-38.64)KS(-30.26)PT(-4.05)KT(4.05)DPK 10 2 741.38419 0.28693 39471 0 0 0 0 0 39471 0 3197 1037 220 220 6506 7443 65735 40307 Mix4_TiO2_1_4 3972 65735 40307 Mix4_TiO2_1_4 3972 Q5JTV8;Q5JTV8-2 Q5JTV8 Q5JTV8 >sp|Q5JTV8|TOIP1_HUMAN Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 PE=1 SV=2;>sp|Q5JTV8-2|TOIP1_HUMAN Isoform 2 of Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 1 76.7668 1 76.7668 2.28659E-18 153.14 0 0 1 67.2814 7.2617E-18 145.45 0.820287 6.91617 0.0185823 63.551 1 74.9968 3.43188E-18 151.37 1 T FSEEGETEEDDQD CK2;FHA1 Rad53p 0.059 2.28659E-18 153.14 _VNFSEEGEpTEEDDQDSSHSSVTTVK_ VNFSEEGET(1)EEDDQDSSHSSVTTVK VNFS(-76.77)EEGET(76.77)EEDDQDS(-92.5)S(-91.17)HS(-98.07)S(-98.07)VT(-97.43)T(-97.43)VK 9 3 946.04873 -0.12509 3695500 6.877 712920 0 0 1964000 0 570010 448500 3198 1043 440 440 5060 5754 48916 29891 Mix4_InSol_TiO2_1 3209 48917 29892 Mix4_InSol_TiO2_1 3212 Q5SNT2 Q5SNT2 Q5SNT2 >sp|Q5SNT2|TM201_HUMAN Transmembrane protein 201 OS=Homo sapiens GN=TMEM201 PE=1 SV=1 0.401914 0 0 0 0.0157823 -16.9991 0.052727 45.098 0.401914 0 0.00207952 75.442 0.00167846 -27.6501 0.0288434 53.006 1 T FRSPRRTSPSSLP FHA KAPP;PKA 0.042 0.00207952 75.442 _RpTSPSSLPGR_ RT(0.402)S(0.402)PS(0.184)S(0.012)LPGR RT(0)S(0)PS(-3.4)S(-15.11)LPGR 2 3 379.85192 -0.25236 0 0 0 0 0 0 0 0 3199 1045 1712 1712 2109;4877 2389;2390;5546;5547 19372 11795 Mix4_TiO2_Reinj_1_5 4932 19367 11782 Mix4_TiO2_1_5 4176 Q5SRE5;Q5SRE5-2 Q5SRE5 Q5SRE5 >sp|Q5SRE5|NU188_HUMAN Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 PE=1 SV=1;>sp|Q5SRE5-2|NU188_HUMAN Isoform 2 of Nucleoporin NUP188 homolog OS=Homo sapiens GN=NUP188 0.943827 12.2537 0.935703 13.2783 1.83343E-16 168.99 0.0487034 -10.5996 0.000240813 96.592 0.943827 12.2537 2.98719E-16 164.62 0.0150418 -15.1488 0.488991 30.221 0.0778795 -9.99393 7.97958E-18 175.63 0.503108 0.0539958 4.91192E-09 123.98 1 T APSSPATGVLPSP CK1;FHA2 Rad53p 0.081 1.83343E-16 168.99 _GAPSSPApTGVLPSPQGK_ GAPSSPAT(0.944)GVLPS(0.056)PQGK GAPS(-85.93)S(-70.04)PAT(12.25)GVLPS(-12.25)PQGK 8 2 815.89545 0.09978 5325000 46822 0 0 4030100 0 0 1248100 3200 1049 1761 1761 2560;2561 2908;2910;2911 24002 14885 Mix4_TiO2_Reinj_1_5 1089 23996 14878 Mix4_InSol_TiO2_1 1224 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.766203 7.68412 0 0 0.766203 7.68412 0.271746 25.851 0 0 0.174168 -6.61769 0.00317244 91.53 0.332456 0 0.00611111 80.984 1 T LVRHASTSSPADK 0.00317244 91.53 _HASpTSSPADKAK_ HAS(0.131)T(0.766)S(0.1)S(0.004)PADKAK HAS(-7.68)T(7.68)S(-8.86)S(-23.29)PADKAK 4 2 640.28755 -0.15013 14927 2.4941 0 0 0 14927 0 0 0 3201 1049 360 360 6006 6846 59284 36025 Mix4_TiO2_Reinj_1_1 4802 59285 36026 Mix4_TiO2_Reinj_1_1 4803 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.831677 7.43206 0.767829 6.96529 8.00277E-24 165.69 0.192624 0 1.10746 22.641 0.831677 7.43206 2.88338E-32 181.34 0 0 0.404216 -0.989352 7.97195E-05 96.097 0.380158 -1.55425 5.59385E-24 168.78 1 T SAQQVRTGSTSSK 2.88338E-32 181.34 _pTGSTSSKEDDYESDAATIVQK_ T(0.832)GS(0.15)T(0.015)S(0.002)S(0.002)KEDDYESDAATIVQK T(7.43)GS(-7.43)T(-17.46)S(-27.31)S(-27.31)KEDDY(-39.8)ES(-82.44)DAAT(-153.2)IVQK 1 3 771.33196 0.39365 3036300 624690 0 0 2411600 0 0 0 3202 1049 363 363 6006 6846 59279 36020 Mix4_InSol_Tio2_Reinj_2 4198 59285 36026 Mix4_TiO2_Reinj_1_1 4803 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.205081 0 0.184246 -1.26858 8.00277E-24 165.69 0.192624 0 1.10746 22.641 0.0633613 -9.39432 2.88338E-32 181.34 0 0 0.159231 -0.501166 7.97195E-05 96.097 0.205081 0 5.59385E-24 168.78 1 T QVRTGSTSSKEDD 2.88338E-32 181.34 _TGpSTSSKEDDYESDAATIVQK_ T(0.179)GS(0.205)T(0.205)S(0.205)S(0.205)KEDDYESDAATIVQK T(-0.58)GS(0)T(0)S(0)S(0)KEDDY(-33.74)ES(-31.9)DAAT(-38.22)IVQK 4 2 1156.4943 0.11938 0 0 0 0 0 0 0 0 3203 1049 2884 2884 6222 7108 61630 37353 Mix4_TiO2_1_1 3385 61631 37354 Mix4_TiO2_Reinj_1_1 3775 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.481424 0 0.481424 0 0.0411702 65.001 0 0 0.45416 -0.798448 3.3147E-08 113.2 0 0 0 0 1 T DGSTLRTSPADHG FHA KAPP 0.155 3.3147E-08 113.2 _pTSPADHGGSVGSESGGSAVDSVAGEHSVSGR_ T(0.481)S(0.481)PADHGGS(0.026)VGS(0.006)ES(0.005)GGSAVDSVAGEHSVSGR T(0)S(0)PADHGGS(-12.66)VGS(-19.28)ES(-19.83)GGS(-31.29)AVDS(-63.17)VAGEHS(-65)VS(-65)GR 1 3 974.08288 0.097578 0 0 0 0 0 0 0 0 0 3204 1054 172 172 5690 6480 55709 34141 Mix4_InSol_Tio2_Reinj_1 7307 55710 34142 Mix4_TiO2_1_3 6133 Q5T8D3-3;Q5T8D3-2;Q5T8D3-4 Q5T8D3-3 Q5T8D3-3 >sp|Q5T8D3-3|ACBD5_HUMAN Isoform 3 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-2|ACBD5_HUMAN Isoform 2 of Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens GN=ACBD5;>sp|Q5T8D3-4|ACBD5_HUMAN Isoform 4 of Ac 0.999838 38.1735 0.997499 26.0095 8.46769E-39 218.58 0.964298 14.4723 2.73904E-21 165.64 0.82402 6.83772 0.0316233 58.889 0.999838 38.1735 7.95436E-32 207.56 1 T GNVLTSTPNAKTV FHA KAPP;NEK6;Polo box;Proline-directed 0.00405 8.46769E-39 218.58 _SSDITSDLGNVLTSpTPNAK_ SSDITSDLGNVLTST(1)PNAK S(-207.21)S(-206.6)DIT(-184.21)S(-172.28)DLGNVLT(-50.19)S(-38.17)T(38.17)PNAK 15 2 1000.4646 -0.7118 2786500 51.249 654620 0 0 1662900 0 141740 327240 3205 1075 813 813 236 271 2342 1500 Mix4_TiO2_Reinj_1_5 8137 2341 1499 Mix4_TiO2_Reinj_1_5 8103 Q66K74 Q66K74 Q66K74 >sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 0.928981 11.1726 0.795437 5.92987 0.00989194 85.358 0.928981 11.1726 0.000403678 98.317 1 T ADSDEDTEGFGVP 0.000403678 98.317 _AGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDpTEGFGVPR_ AGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADS(0.071)DEDT(0.929)EGFGVPR AGGLGAEET(-61.77)PPT(-59.55)S(-59.55)VS(-59.61)ES(-59.61)LPT(-54.68)LS(-48.22)DS(-40.65)DPVPLAPGAADS(-11.17)DEDT(11.17)EGFGVPR 40 4 1169.5328 0.57861 2145600 351490 0 0 1794100 0 0 0 3206 1090 442 442 6541 7484 66056 40536 Mix4_TiO2_Reinj_1_2 5922 66056 40536 Mix4_TiO2_Reinj_1_2 5922 Q6N075 Q6N075 Q6N075 >sp|Q6N075|MFSD5_HUMAN Major facilitator superfamily domain-containing protein 5 OS=Homo sapiens GN=MFSD5 PE=2 SV=2 0.499999 0 0.498927 0 0.369255 23.665 0 0 0.499999 0 0.00547829 78.63 0 0 1 T LRVPSPTEEPYAP 0.00547829 78.63 _VPpSPTEEPYAPEL_ VPS(0.5)PT(0.5)EEPYAPEL VPS(0)PT(0)EEPY(-56.65)APEL 5 2 754.83145 -0.11368 144550 0 0 0 144550 0 0 0 3207 1099 727 727 6200 7082 61457 37254 Mix4_TiO2_1_6 7002 61455 37252 Mix4_TiO2_1_5 8381 Q6P2E9;Q6P2E9-2 Q6P2E9 Q6P2E9 >sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 PE=1 SV=1;>sp|Q6P2E9-2|EDC4_HUMAN Isoform 2 of Enhancer of mRNA-decapping protein 4 OS=Homo sapiens GN=EDC4 0.787976 8.26537 0.787976 8.26537 3.51953E-12 126.51 0 0 1 T QASPSRTRSPDVI 3.51953E-12 126.51 _pTRSPDVISSASTALSQDIPEIASEALSR_ T(0.788)RS(0.117)PDVIS(0.024)S(0.024)AS(0.024)T(0.024)ALSQDIPEIASEALSR T(8.27)RS(-8.27)PDVIS(-15.23)S(-15.23)AS(-15.23)T(-15.23)ALS(-46.91)QDIPEIAS(-96.09)EALS(-96.09)R 1 3 994.48696 1.7536 50656 50656 0 0 0 0 0 0 3208 1103 716 716 6253 7144 62155 37714 Mix4_TiO2_1_6 6607 62158 37717 Mix4_TiO2_Reinj_1_3 8854 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.401188 1.64742 0.401188 1.64742 5.62867E-12 134.41 0.318212 0 0.736971 33.214 0.33314 0 4.67145E-25 171.98 0.26953 -0.348215 1.72588 12.464 0.167811 -3.97587 8.78517E-07 100.84 0.308741 -0.824573 9.30511E-07 99.822 1 T IGFGDRTSTFCGT 4.67145E-25 171.98 _pTSTFCGTPEFLAPEVLTQEAYTR_ T(0.401)S(0.275)T(0.275)FCGT(0.049)PEFLAPEVLTQEAYTR T(1.65)S(-1.65)T(-1.65)FCGT(-9.1)PEFLAPEVLT(-35.77)QEAY(-35.77)T(-35.77)R 1 2 1349.609 0.016073 0 0 0 0 0 0 0 0 3209 1103 718 718 6253 7144 62158 37717 Mix4_TiO2_Reinj_1_3 8854 62158 37717 Mix4_TiO2_Reinj_1_3 8854 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.368656 0 0.360222 0 5.62867E-12 134.41 0.318212 0 0.736971 33.214 0.368656 0 4.67145E-25 171.98 0.292031 0 1.72588 12.464 0.206502 -3.07482 8.78517E-07 100.84 0.286163 -1.15437 9.30511E-07 99.822 1 T FGDRTSTFCGTPE CAMK2 0.042 4.67145E-25 171.98 _TpSTFCGTPEFLAPEVLTQEAYTR_ T(0.259)S(0.369)T(0.369)FCGT(0.004)PEFLAPEVLTQEAYTR T(-1.54)S(0)T(0)FCGT(-19.76)PEFLAPEVLT(-116.86)QEAY(-169.08)T(-170.97)R 3 3 900.07506 0.0060669 0 0 0 0 0 0 0 0 3210 1103 722 722 6253 7144 62147 37701 Mix4_InSol_Tio2_Reinj_2 6035 62158 37717 Mix4_TiO2_Reinj_1_3 8854 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.707918 8.56876 0.102414 -6.49066 5.62867E-12 134.41 0.0449078 -8.50395 0.736971 33.214 0.0368503 -9.40131 4.67145E-25 171.98 0.0853664 -5.34142 1.72588 12.464 0.419185 3.07482 8.78517E-07 100.84 0.707918 8.56876 9.30511E-07 99.822 1 T TSTFCGTPEFLAP Proline-directed 0.05 4.67145E-25 171.98 _TSTFCGpTPEFLAPEVLTQEAYTR_ T(0.095)S(0.098)T(0.098)FCGT(0.708)PEFLAPEVLTQEAYTR T(-8.72)S(-8.57)T(-8.57)FCGT(8.57)PEFLAPEVLT(-37.35)QEAY(-43.61)T(-43.61)R 7 2 1349.609 0.69401 142000 0 0 0 0 0 0 142000 3211 1103 860 860 6726 7699 68192 41807 Mix4_TiO2_Reinj_1_3 8356 68192 41807 Mix4_TiO2_Reinj_1_3 8356 Q6P5Z2 Q6P5Z2 Q6P5Z2 >sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 0.999794 39.878 0.936577 14.7033 3.92495E-05 97.19 0.97355 18.6702 0.000355702 83.798 0.999794 39.878 4.95729E-07 102.38 0 0 0 0 1 T GLPPALTPPAPHS FHA KAPP;Proline-directed 0.05 4.95729E-07 102.38 _YFEGEFTGLPPALpTPPAPHSLLTAR_ YFEGEFTGLPPALT(1)PPAPHSLLTAR Y(-102.38)FEGEFT(-62.58)GLPPALT(39.88)PPAPHS(-39.88)LLT(-39.88)AR 14 3 921.45783 0.31187 1978700 258450 365090 0 1355200 0 0 0 3212 1113 526 526 630 725 5991 3512 Mix4_InSol_Tio2_Reinj_1 4930 5994 3515 Mix4_TiO2_1_5 3945 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.999998 56.7972 0.998118 27.491 0.000964354 91.361 0.999581 33.9388 0.00125093 89.118 0 0 0.695854 8.36557 1.166 8.3656 0.999998 56.7972 0.00153421 86.901 1 T GSPRAVTPVPTKT CAMK2;Proline-directed 0.042 0.000964354 91.361 _AVpTPVPTKTEEVSNLK_ AVT(1)PVPTKTEEVSNLK AVT(56.8)PVPT(-56.8)KT(-69.99)EEVS(-86.9)NLK 3 2 896.95825 0.024133 954180 506470 154710 0 0 0 32102 260890 3213 1113 769 769 5459 6211;6212 53241 32542 Mix4_InSol_TiO2_2 4100 53243 32545 Mix4_TiO2_Reinj_1_5 5168 Q6PKG0;Q6PKG0-3 Q6PKG0 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2;>sp|Q6PKG0-3|LARP1_HUMAN Isoform 2 of La-related protein 1 OS=Homo sapiens GN=LARP1 0.402351 0 1.02355E-05 -49.8989 0.000396588 106.22 0.000103854 -39.5657 0.114168 39.566 0.00395915 -24.0003 0.0327952 57.02 0 0 0.402351 0 0.0327953 57.02 0.0387319 -13.8645 0.107995 39.95 2 T IARSLPTTVPESP CK1 0.081 0.0327952 57.02 _pSLPTTVPEpSPNYR_ S(0.402)LPT(0.402)T(0.208)VPES(0.962)PNY(0.026)R S(0)LPT(0)T(-3.06)VPES(17.59)PNY(-17.59)R 4 2 810.83896 0.37473 0 0 0 0 0 0 0 0 3214 1122 404 404 6423 7347 64861 39795 Mix4_TiO2_2_2 3708 64863 39797 Mix4_TiO2_Reinj_1_5 4440 Q6Y7W6-3;Q6Y7W6 Q6Y7W6-3 Q6Y7W6-3 >sp|Q6Y7W6-3|PERQ2_HUMAN Isoform 2 of PERQ amino acid-rich with GYF domain-containing protein 2 OS=Homo sapiens GN=GIGYF2;>sp|Q6Y7W6|PERQ2_HUMAN PERQ amino acid-rich with GYF domain-containing protein 2 OS=Homo sapiens GN=GIGYF2 PE=1 SV=1 0.970818 22.8657 0 0 0.970818 22.8657 0.000131099 95.531 0.778685 6.71277 1.55276E-07 109.98 0 0 0 0 0.270908 3.16655 1.45192 38.254 1 T SSARPGTPSDHQS CAMK2;CK2;ERK/MAPK;FHA1 Rad53p;Proline-directed 0.0025 1.55276E-07 109.98 _VGVEASEETPQTSSSSARPGpTPSDHQSQEASQFER_ VGVEASEETPQT(0.005)S(0.005)S(0.005)S(0.005)S(0.005)ARPGT(0.971)PS(0.004)DHQSQEASQFER VGVEAS(-43.29)EET(-39.54)PQT(-22.87)S(-22.87)S(-22.87)S(-22.87)S(-22.87)ARPGT(22.87)PS(-24.05)DHQS(-39.54)QEAS(-54.36)QFER 21 3 1261.8837 0.12774 3023400 0 87625 0 2935800 0 0 0 3215 1125 1867 1867 1062 1194 9980 6087 Mix4_TiO2_1_1 6526 9980 6087 Mix4_TiO2_1_1 6526 Q6ZNJ1;Q6ZNJ1-2;Q6ZNJ1-3 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2;>sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like protein 2 OS=Homo sap 0.999218 31.0647 0.999218 31.0647 5.7832E-24 162.85 0.427278 -0.43157 0.945046 28.159 0.996121 24.1011 9.66845E-18 155.26 0 0 0 0 1 T LGEVPLTPTEEAS CK2;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 5.7832E-24 162.85 _DNLGEVPLpTPTEEASLPLAVTK_ DNLGEVPLT(0.999)PT(0.001)EEASLPLAVTK DNLGEVPLT(31.06)PT(-31.06)EEAS(-65.76)LPLAVT(-112.32)K 9 2 1187.5931 0.6421 2537200 390840 0 0 2146400 0 0 0 3216 1125 1869 1869 1062 1194 9982 6089 Mix4_TiO2_2_1 4568 9980 6087 Mix4_TiO2_1_1 6526 Q6ZNJ1;Q6ZNJ1-2;Q6ZNJ1-3 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2;>sp|Q6ZNJ1-3|NBEL2_HUMAN Isoform 3 of Neurobeachin-like protein 2 OS=Homo sap 0.471919 0.43157 0.0256557 -15.7951 5.7832E-24 162.85 0.471919 0.43157 0.945046 28.159 0.0332277 -14.6382 9.66845E-18 155.26 0 0 0 0 1 T EVPLTPTEEASLP FHA KAPP;NEK6 0.076 5.7832E-24 162.85 _DNLGEVPLTPpTEEASLPLAVTK_ DNLGEVPLT(0.427)PT(0.472)EEAS(0.1)LPLAVT(0.001)K DNLGEVPLT(-0.43)PT(0.43)EEAS(-6.75)LPLAVT(-26.4)K 11 2 1187.5931 0.16881 0 0 0 0 0 0 0 0 3217 1125 764 764 5651 6437 55178 33767 Mix4_TiO2_Reinj_1_1 8215 55177 33765 Mix4_TiO2_Reinj_1_1 8195 Q6ZNJ1;Q6ZNJ1-2 Q6ZNJ1 Q6ZNJ1 >sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 PE=1 SV=2;>sp|Q6ZNJ1-2|NBEL2_HUMAN Isoform 2 of Neurobeachin-like protein 2 OS=Homo sapiens GN=NBEAL2 0.244367 0 0.108032 -5.79812 0.13129 67.474 0 0 0.244367 0 9.8556E-09 117.95 1 T QSVPASTGLGWGS 9.8556E-09 117.95 _SQSVPApSTGLGWGSGLVAPLQEGSIDSTLAGTQDTR_ S(0.2)QS(0.066)VPAS(0.244)T(0.244)GLGWGS(0.244)GLVAPLQEGSIDSTLAGTQDTR S(-0.86)QS(-5.7)VPAS(0)T(0)GLGWGS(0)GLVAPLQEGS(-31.58)IDS(-31.43)T(-31.58)LAGT(-39.82)QDT(-40.99)R 8 4 906.68608 0.11573 0 0 0 0 0 0 0 0 3218 1131 906 906 4008 4565 37911 23273 Mix4_TiO2_Reinj_1_1 8256 37911 23273 Mix4_TiO2_Reinj_1_1 8256 Q6ZS30;Q6ZS30-1 Q6ZS30 Q6ZS30 >sp|Q6ZS30|NBEL1_HUMAN Neurobeachin-like protein 1 OS=Homo sapiens GN=NBEAL1 PE=2 SV=3;>sp|Q6ZS30-1|NBEL1_HUMAN Isoform 1 of Neurobeachin-like protein 1 OS=Homo sapiens GN=NBEAL1 0.946777 12.5202 0 0 0.946777 12.5202 0.0125725 66.546 1 T TVPESVTPVEGDW CK2;Proline-directed 0.05 0.0125725 66.546 _NESTVPESVpTPVEGDWLVWTSTK_ NESTVPES(0.053)VT(0.947)PVEGDWLVWTSTK NES(-37.54)T(-41.87)VPES(-12.52)VT(12.52)PVEGDWLVWT(-62.82)S(-66.55)T(-66.55)K 10 3 881.07382 0.18646 58272 0 0 0 58272 0 0 0 3219 1132 180 180 3094 3516;3517 29412 18338 Mix4_TiO2_Reinj_1_5 7890 29407 18336 Mix4_TiO2_Reinj_1_5 7703 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 0.585682 1.51978 0.429391 0 0.0356471 76.395 0.585682 1.51978 1.64663E-11 121.06 1 T KSMEELTVIQCTS PLK1 0.033462 1.64663E-11 121.06 _KKSMEELpTVIQCTSQELPAQTGLLSQTGDVPLPAGR_ KKS(0.413)MEELT(0.586)VIQCT(0.001)SQELPAQTGLLSQTGDVPLPAGR KKS(-1.52)MEELT(1.52)VIQCT(-26.24)S(-37.02)QELPAQT(-39.92)GLLS(-56.32)QT(-68.52)GDVPLPAGR 8 4 991.49553 -0.088085 1638600 0 0 0 1638600 0 0 0 3220 1132 185 185 3094 3516;3517 29406 18335 Mix4_TiO2_Reinj_1_5 7692 29407 18336 Mix4_TiO2_Reinj_1_5 7703 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 0.387013 0 0.0637853 -10.0725 0.0356471 76.395 0.387013 0 1.64663E-11 121.06 1 T LTVIQCTSQELPA CK2 0.117 1.64663E-11 121.06 _KKSM(ox)EELTVIQCpTSQELPAQTGLLSQTGDVPLPAGR_ KKS(0.109)MEELT(0.109)VIQCT(0.387)S(0.387)QELPAQT(0.007)GLLS(0.001)QTGDVPLPAGR KKS(-5.51)MEELT(-5.51)VIQCT(0)S(0)QELPAQT(-17.23)GLLS(-27.84)QT(-30.49)GDVPLPAGR 13 4 995.49426 0.34042 0 0 0 0 0 0 0 0 3221 1136 199 199 6641 7603 67380 41395 Mix4_TiO2_1_4 3509 67378 41393 Mix4_InSol_TiO2_1 4421 Q6ZUT6;Q6ZUT6-4;Q6ZUT6-3 Q6ZUT6 Q6ZUT6 >sp|Q6ZUT6|CO052_HUMAN Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52 PE=1 SV=1;>sp|Q6ZUT6-4|CO052_HUMAN Isoform 4 of Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52;>sp|Q6ZUT6-3|CO052_HUMAN Isoform 3 of Uncharacterized protein C 0.772728 6.28305 0.772728 6.28305 0.435509 31.973 0.272524 -2.21607 0.455068 31.341 0.149645 -4.53506 0.0292389 59.549 0.358591 0.554305 0.803487 20.248 1 T SPGGRVTRSPPTQ PKA 0.042 0.0292389 59.549 _VpTRSPPTQVAISSDSAR_ VT(0.773)RS(0.182)PPT(0.044)QVAISSDSAR VT(6.28)RS(-6.28)PPT(-12.45)QVAIS(-31.97)S(-31.97)DS(-31.97)AR 2 3 617.97019 0.34649 31489 31489 0 0 0 0 0 0 3222 1136 204 204 6641 7603 67381 41396 Mix4_TiO2_Reinj_1_4 4047 67378 41393 Mix4_InSol_TiO2_1 4421 Q6ZUT6;Q6ZUT6-4;Q6ZUT6-3 Q6ZUT6 Q6ZUT6 >sp|Q6ZUT6|CO052_HUMAN Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52 PE=1 SV=1;>sp|Q6ZUT6-4|CO052_HUMAN Isoform 4 of Uncharacterized protein C15orf52 OS=Homo sapiens GN=C15orf52;>sp|Q6ZUT6-3|CO052_HUMAN Isoform 3 of Uncharacterized protein C 0.453953 2.21607 0.0439475 -12.4509 0.435509 31.973 0.453953 2.21607 0.455068 31.341 0.425177 0 0.0292389 59.549 0.315624 -0.554305 0.803487 20.248 1 T VTRSPPTQVAISS CK1;FHA KAPP 0.081 0.0292389 59.549 _VTRSPPpTQVAISSDSAR_ VT(0.273)RS(0.273)PPT(0.454)QVAISSDSAR VT(-2.22)RS(-2.22)PPT(2.22)QVAIS(-31.34)S(-31.34)DS(-31.34)AR 7 3 617.97019 -0.049208 0 0 0 0 0 0 0 0 3223 1137 1113 1113 4944 5620 47547 29018 Mix4_TiO2_Reinj_1_5 6030 47546 29017 Mix4_TiO2_1_5 5210 Q6ZUT9-2;Q6ZUT9 Q6ZUT9-2 Q6ZUT9-2 >sp|Q6ZUT9-2|DEN5B_HUMAN Isoform 2 of DENN domain-containing protein 5B OS=Homo sapiens GN=DENND5B;>sp|Q6ZUT9|DEN5B_HUMAN DENN domain-containing protein 5B OS=Homo sapiens GN=DENND5B PE=1 SV=2 0.497792 0 0.451165 0 0.00448712 68.018 0.497792 0 0.210953 28.878 1 T ARRLSITSLTGKN NEK6 0.076 0.00448712 68.018 _RLSIpTSLTGK_ RLS(0.003)IT(0.498)S(0.498)LT(0.001)GK RLS(-22.07)IT(0)S(0)LT(-25.75)GK 5 2 578.3103 0.12826 0 0 0 0 0 0 0 0 3224 1141 3350 3350 772;6036 879;6885 59659 36201 Mix4_TiO2_Reinj_1_1 1759 59659 36201 Mix4_TiO2_Reinj_1_1 1759 Q70CQ2;Q70CQ2-2;Q70CQ2-3 Q70CQ2 Q70CQ2 >sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2;>sp|Q70CQ2-2|UBP34_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34;>sp|Q70CQ2-3|UBP34_HUMAN Isoform 3 of Ubiquitin carbo 1 75.9726 0 0 1 75.9726 0.00848233 75.973 0.999993 51.8417 0.0468421 51.842 0.999997 55.4261 0.0341815 55.426 1 T KDDEGATPIKRRR CDK1;CDK2;Proline-directed 0.0057 0.00848233 75.973 _TKDDEGApTPIKR_ TKDDEGAT(1)PIKR T(-75.97)KDDEGAT(75.97)PIKR 8 2 705.83486 0.017264 345110 0 0 0 225780 0 67723 51604 3225 1141 3381 3381 1914 2163;2164 17572 10528 Mix4_TiO2_Reinj_1_1 3177 17571 10526 Mix4_TiO2_1_1 2633 Q70CQ2;Q70CQ2-2;Q70CQ2-3 Q70CQ2 Q70CQ2 >sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2;>sp|Q70CQ2-2|UBP34_HUMAN Isoform 2 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34;>sp|Q70CQ2-3|UBP34_HUMAN Isoform 3 of Ubiquitin carbo 0.993962 23.9158 0.658696 4.45451 0.000125151 107.41 0 0 0.993962 23.9158 0.000392534 97.787 0 0 0.96369 14.4999 0.174907 37.448 0 0 1 T ETREVLTPTSTSD ERK/MAPK;FHA KAPP;Proline-directed 0.0034 0.000125151 107.41 _EVLpTPTSTSDNETR_ EVLT(0.994)PT(0.004)S(0.001)T(0.001)SDNETR EVLT(23.92)PT(-23.92)S(-30.03)T(-30.03)S(-45.11)DNET(-81.91)R 4 2 815.35381 -0.30056 247360 46932 0 0 174890 0 25540 0 3226 1144 601 601 538 612 5045 3040 Mix4_TiO2_1_5 5393 5045 3040 Mix4_TiO2_1_5 5393 Q71RC2-4;Q71RC2;Q71RC2-3 Q71RC2-4 Q71RC2-4 >sp|Q71RC2-4|LARP4_HUMAN Isoform 4 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC2|LARP4_HUMAN La-related protein 4 OS=Homo sapiens GN=LARP4 PE=1 SV=3;>sp|Q71RC2-3|LARP4_HUMAN Isoform 3 of La-related protein 4 OS=Homo sapiens GN=LARP4 0.394261 0 0.394261 0 2.60248E-07 112.99 0.0995925 -7.12394 0.123841 51.829 1 T KPSRASTASPCNN CAMK2 0.042 2.60248E-07 112.99 _ApSTASPCNNNINAATAVALQEPR_ AS(0.394)T(0.394)AS(0.211)PCNNNINAATAVALQEPR AS(0)T(0)AS(-2.71)PCNNNINAAT(-62.32)AVALQEPR 3 3 817.37584 -0.23834 0 0 0 0 0 0 0 0 3227 1144 594 594 875 986 8298 5004 Mix4_TiO2_1_3 4602 8301 5008 Mix4_TiO2_Reinj_1_5 5330 Q71RC2-4;Q71RC2;Q71RC2-3;Q71RC2-2 Q71RC2-4 Q71RC2-4 >sp|Q71RC2-4|LARP4_HUMAN Isoform 4 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC2|LARP4_HUMAN La-related protein 4 OS=Homo sapiens GN=LARP4 PE=1 SV=3;>sp|Q71RC2-3|LARP4_HUMAN Isoform 3 of La-related protein 4 OS=Homo sapiens GN=LARP4;>sp|Q71RC 0.481056 2.2534 0.481056 2.2534 0.000110544 95.832 0 0 0.0189758 -16.9628 1.78906E-10 121.83 1 T VSPPSTTKPSRAS FHA KAPP 0.155 1.78906E-10 121.83 _DGLNQTTIPVSPPSTpTKPSR_ DGLNQTTIPVS(0.286)PPS(0.078)T(0.078)T(0.481)KPS(0.078)R DGLNQT(-82.19)T(-67.04)IPVS(-2.25)PPS(-7.93)T(-7.93)T(2.25)KPS(-7.93)R 16 3 726.02637 0.14677 0 0 0 0 0 0 0 0 3228 1146 888 888 2014 2282 18487 11204 Mix4_TiO2_1_5 4283 18487 11204 Mix4_TiO2_1_5 4283 Q76FK4;Q76FK4-4;Q76FK4-2;Q76FK4-3 Q76FK4 Q76FK4 >sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1;>sp|Q76FK4-4|NOL8_HUMAN Isoform 4 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-2|NOL8_HUMAN Isoform 2 of Nucleolar protein 8 OS=Homo sapiens GN=NOL8;>sp|Q76FK4-3|NOL8_ 1 150.259 1 150.259 1.25096E-12 150.26 2 T DSRFLETDSEEEQ CK2 0.117 1.25096E-12 150.26 _FLEpTDpSEEEQEEVNEK_ FLET(1)DS(1)EEEQEEVNEK FLET(150.26)DS(150.26)EEEQEEVNEK 4 2 1057.89 0.10441 54166 54166 0 0 0 0 0 0 3229 1147;1148;1149 42;9;9 9 2413;4294 2734;4885 22549 14076 Mix4_InSol_Tio2_Reinj_2 3257 22552 14081 Mix4_TiO2_Reinj_1_3 3990 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.470584 0 0.128838 -7.37851 0.00918167 73.864 0.109223 -8.98482 4.38634E-06 105.81 0.204235 -2.77909 0.00139121 81.921 0.470584 0 0.0110355 71.209 1 T RGRNSATSADEQP CK2;FHA1 Rad53p 0.059 4.38634E-06 105.81 _GRNpSATSADEQPHIGNYR_ GRNS(0.471)AT(0.471)S(0.058)ADEQPHIGNYR GRNS(0)AT(0)S(-9.06)ADEQPHIGNY(-31.44)R 6 3 684.96762 0.71752 0 0 0 0 0 0 0 0 0 3230 1147;1148;1149 208;175;175 175 2689;3362 3062;3803 31685 19605 Mix4_TiO2_Reinj_1_3 7911 31677 19590 Mix4_TiO2_1_3 7130 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 1 79.6197 1 89.4678 5.47474E-32 209.73 0.999862 38.6311 0.000479152 90.715 1 79.6197 7.64911E-26 176.24 0.938257 13.2864 0.229126 58.143 1 65.2413 1.35075E-10 132.64 0.999992 50.7817 0.00016147 96.142 1 T FGNKLDTFCGSPP 5.47474E-32 209.73 _LDpTFCGSPPYAAPELFQGK_ LDT(1)FCGSPPYAAPELFQGK LDT(79.62)FCGS(-79.62)PPY(-134.48)AAPELFQGK 3 2 1089.4843 0.34998 25695000 9017200 41928 0 16253000 186810 104650 91517 3231 1147;1148;1149 466;432;432 432 3097;6262 3520;7153 29459 18367 Mix4_TiO2_Reinj_1_5 4026 62356 37944 Mix4_TiO2_Reinj_1_3 4472 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.765403 6.00178 0.404677 0.261489 2.32057E-20 184.57 0 0 0.765403 6.00178 1.40651E-20 188.76 0.489992 0 1.01117E-16 172.1 0.098915 -0.452006 9.32357E-13 146.09 1 T GLERKKTTPTPST CAMK2;CHK1;CHK1/2;PKA;PKD 0.003192 1.40651E-20 188.76 _KKpTTPTPSTNSVLSTSTNR_ KKT(0.765)T(0.192)PT(0.03)PS(0.005)T(0.007)NSVLSTSTNR KKT(6)T(-6)PT(-14.08)PS(-21.57)T(-20.42)NS(-34.97)VLS(-83.48)T(-83.48)S(-83.48)T(-83.48)NR 3 3 700.6826 0.50958 127230 0 0 0 127230 0 0 0 3232 1147;1148;1149 467;433;433 433 3097;6262 3520;7153 29457 18365 Mix4_TiO2_Reinj_1_3 3949 62356 37944 Mix4_TiO2_Reinj_1_3 4472 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.781406 6.99498 0.381031 -0.261489 2.32057E-20 184.57 0 0 0.781406 6.99498 1.40651E-20 188.76 0.489992 0 1.01117E-16 172.1 0.098915 -0.452006 9.32357E-13 146.09 1 T LERKKTTPTPSTN Proline-directed 0.05 1.40651E-20 188.76 _KKTpTPTPSTNSVLSTSTNR_ KKT(0.156)T(0.781)PT(0.021)PS(0.021)T(0.021)NSVLSTSTNR KKT(-6.99)T(6.99)PT(-15.74)PS(-15.74)T(-15.74)NS(-59.52)VLS(-153.27)T(-157.74)S(-157.74)T(-157.74)NR 4 3 700.6826 0.033346 1826100 0 0 0 1826100 0 0 0 3233 1147;1148;1149 472;438;438 438 3097;6262 3520;7153 62357 37945 Mix4_TiO2_Reinj_1_3 4725 62356 37944 Mix4_TiO2_Reinj_1_3 4472 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.808777 7.02593 0.782028 6.30912 2.32057E-20 184.57 0 0 0.808777 7.02593 1.40651E-20 188.76 8.4084E-05 -37.6548 1.01117E-16 172.1 0.098915 -0.452006 9.32357E-13 146.09 1 T TTPTPSTNSVLST 1.40651E-20 188.76 _TTPTPSpTNSVLSTSTNR_ TTPTPS(0.031)T(0.809)NS(0.16)VLSTSTNR T(-119.22)T(-118.25)PT(-70.12)PS(-14.19)T(7.03)NS(-7.03)VLS(-51.87)T(-68.49)S(-77.13)T(-83.07)NR 7 2 922.4253 0.18041 821030 220030 0 0 601000 0 0 0 3234 1147;1148;1149 480;446;446 446 3097;6262 3520;7153 62352 37940 Mix4_InSol_TiO2_1 4762 62356 37944 Mix4_TiO2_Reinj_1_3 4472 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.605449 1.95754 0.124572 -8.4547 2.32057E-20 184.57 0 0 0.600675 1.77801 1.40651E-20 188.76 0.605449 1.95754 1.01117E-16 172.1 0.58615 1.52046 9.32357E-13 146.09 1 T SVLSTSTNRSRNS CK1;FHA KAPP 0.081 1.40651E-20 188.76 _TTPTPSTNSVLSTSpTNR_ TTPTPSTNSVLST(0.009)S(0.386)T(0.605)NR T(-172.1)T(-172.1)PT(-171.01)PS(-124.96)T(-118.18)NS(-104.23)VLS(-46.9)T(-18.39)S(-1.96)T(1.96)NR 15 2 922.4253 0.53692 1302600 0 0 0 997210 0 143740 161670 3235 1147;1148;1149 384;351;351 351 4436;4437;5698 5046;5047;6491 55857 34205 Mix4_InSol_Tio2_Reinj_1 5900 42201 25990 Mix4_TiO2_Reinj_1_3 3034 Q7KZI7;Q7KZI7-8;Q7KZI7-11;Q7KZI7-6;Q7KZI7-3;Q7KZI7-12;Q7KZI7-13;Q7KZI7-2;Q7KZI7-7;Q7KZI7-10;Q7KZI7-14 Q7KZI7;Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7|MARK2_HUMAN Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2;>sp|Q7KZI7-8|MARK2_HUMAN Isoform 8 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-11|MARK2_HUMAN Isoform 11 of Serine/threonine-pr 0.342295 0.52344 2.86521E-07 -65.1377 1.01535E-08 123.91 0.00145898 -27.0728 0.54606 27.073 0.0570095 -8.69129 1.11684E-12 150.94 0 0 0.144973 -5.4568 0.034985 64.11 0.342295 0.52344 0.0162928 64.412 1 T RPSADLTNSSAPS FHA KAPP 0.155 1.11684E-12 150.94 _SSELEGDTITLKPRPSADLpTNSSAPSPSHK_ SSELEGDT(0.001)IT(0.018)LKPRPS(0.091)ADLT(0.342)NS(0.081)S(0.081)APS(0.303)PS(0.081)HK S(-34.86)S(-34.63)ELEGDT(-26.7)IT(-12.83)LKPRPS(-5.75)ADLT(0.52)NS(-6.23)S(-6.23)APS(-0.52)PS(-6.23)HK 20 3 1068.1803 -0.39344 0 0 0 0 0 0 0 0 3236 1148;1149 385;385 385 2055;2056;4869;4870 2329;2330;5535;5536 46731 28613 Mix4_TiO2_1_3 3998 18853 11511 Mix4_TiO2_1_3 4359 Q7KZI7-13;Q7KZI7-14 Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-14|MARK2_HUMAN Isoform 14 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 0.354362 0 0.354362 0 1.99861E-16 168.39 0 0 0.349158 3.31612 3.95798E-16 160.94 0.306143 0 1.86764E-15 146.07 0.131562 -4.15141 4.84304E-06 104.53 1 T AGPAIPTSNSYSK FHA KAPP 0.155 1.99861E-16 168.39 _RFSDQAGPAIPpTSNSYSKK_ RFSDQAGPAIPT(0.354)S(0.354)NS(0.097)Y(0.097)S(0.097)KK RFS(-37.25)DQAGPAIPT(0)S(0)NS(-5.62)Y(-5.62)S(-5.62)KK 12 3 712.00368 -0.22319 0 0 0 0 0 0 0 0 3237 1152 1234 1234 5287 6018 51301 31421 Mix4_TiO2_1_5 2317 51302 31422 Mix4_TiO2_Reinj_1_5 2938 Q7L576;Q7L576-2;Q7L576-3 Q7L576 Q7L576 >sp|Q7L576|CYFP1_HUMAN Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens GN=CYFIP1 PE=1 SV=1;>sp|Q7L576-2|CYFP1_HUMAN Isoform 4 of Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens GN=CYFIP1;>sp|Q7L576-3|CYFP1_HUMAN Isoform 5 of Cytoplasmic FMR1- 0.999958 43.7701 0.999958 43.7701 0.0157708 66.403 0 0 0.999671 34.8308 0.00405925 82.664 0 0 0 0 1 T SGDGEGTPVEHVR CK2;Proline-directed 0.05 0.00405925 82.664 _SGDGEGpTPVEHVR_ SGDGEGT(1)PVEHVR S(-43.77)GDGEGT(43.77)PVEHVR 7 2 710.29864 -0.14791 188970 3.1341 33441 0 0 155530 0 0 0 3238 1154 35 35 2553 2898 23904 14829 Mix4_TiO2_Reinj_1_6 3303 23904 14829 Mix4_TiO2_Reinj_1_6 3303 Q7L9L4;Q9H8S9;Q9H8S9-2 Q7L9L4 Q7L9L4 >sp|Q7L9L4|MOL1A_HUMAN Mps one binder kinase activator-like 1A OS=Homo sapiens GN=MOBKL1A PE=1 SV=3;>sp|Q9H8S9|MOL1B_HUMAN Mps one binder kinase activator-like 1B OS=Homo sapiens GN=MOBKL1B PE=1 SV=4;>sp|Q9H8S9-2|MOL1B_HUMAN Isoform 2 of Mps one binder kin 0.999955 43.4232 0.999925 41.2688 0.0152351 63.776 0.999955 43.4232 0.003537 90.221 0 0 0.999881 39.2423 0.0193289 59.631 1 T LKHAEATLGSGNL FHA KAPP;PLK1 0.033462 0.003537 90.221 _HAEApTLGSGNLR_ HAEAT(1)LGSGNLR HAEAT(43.42)LGS(-43.42)GNLR 5 2 653.30099 0.75235 731970 151300 0 0 516190 0 0 64484 3239 1161 1188 1188 1191 1338;1341 11180 6848 Mix4_TiO2_Reinj_1_1 8366 11180 6848 Mix4_TiO2_Reinj_1_1 8366 Q7Z3U7;Q7Z3U7-4;Q7Z3U7-2;Q7Z3U7-3 Q7Z3U7 Q7Z3U7 >sp|Q7Z3U7|MON2_HUMAN Protein MON2 homolog OS=Homo sapiens GN=MON2 PE=1 SV=2;>sp|Q7Z3U7-4|MON2_HUMAN Isoform 4 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-2|MON2_HUMAN Isoform 2 of Protein MON2 homolog OS=Homo sapiens GN=MON2;>sp|Q7Z3U7-3|MO 0.804071 6.13196 0.499999 0 0.00340025 77.353 0 0 0.804071 6.13196 7.7747E-12 119.35 1 T DSDKPETPPVVNV ERK/MAPK;Proline-directed;WW GroupIV 0.000145 7.7747E-12 119.35 _DSDKPEpTPPVVNVPVPVLIGPISGMSR_ DS(0.196)DKPET(0.804)PPVVNVPVPVLIGPISGMSR DS(-6.13)DKPET(6.13)PPVVNVPVPVLIGPIS(-119.35)GMS(-119.35)R 7 3 960.82408 0.038851 610560 1.69 67385 0 0 543180 0 0 0 3240 1163 631 631 1348 1518 12692 7842 Mix4_InSol_TiO2_1 8137 12700 7853 Mix4_TiO2_Reinj_1_3 7647 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 0.80962 7.12165 0.225124 -5.34171 5.96871E-24 162.43 0.156192 -7.29723 7.31054E-25 174.3 0.80962 7.12165 5.65727E-07 106.96 0.150699 -6.66028 0.000277407 89.954 1 T NPLASPTNTLLGS FHA2 Rad53p 0.114 7.31054E-25 174.3 _DYEIESQNPLASPpTNTLLGSAK_ DYEIESQNPLAS(0.015)PT(0.81)NT(0.157)LLGS(0.019)AK DY(-106.96)EIES(-92.23)QNPLAS(-17.43)PT(7.12)NT(-7.12)LLGS(-16.37)AK 14 3 810.0475 0.15264 156400 0 0 0 0 0 156400 0 3241 1163 220 220 2087 2364 19126 11635 Mix4_TiO2_Reinj_1_3 2573 19123 11631 Mix4_InSol_Tio2_Reinj_1 3157 Q7Z417 Q7Z417 Q7Z417 >sp|Q7Z417|NUFP2_HUMAN Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens GN=NUFIP2 PE=1 SV=1 0.974339 17.1795 0.873885 8.42749 3.49355E-09 127.87 0.974339 17.1795 0.0079057 74.477 3.55018E-13 -124.496 1.09732E-09 134.38 3.75687E-15 -144.25 2.40352E-13 153.93 1 T SESGYTTPKKRKA CDK1;CDK2;Proline-directed 0.0057 2.40352E-13 153.93 _GADNDGSGSESGYTpTPK_ GADNDGSGS(0.001)ES(0.003)GY(0.002)T(0.019)T(0.974)PK GADNDGS(-40.63)GS(-28.16)ES(-25.1)GY(-26.05)T(-17.18)T(17.18)PK 15 2 861.82816 0.58797 120500 25695 0 0 94805 0 0 0 3242 1164 252 252 3625 4085 34085 21032 Mix4_TiO2_Reinj_1_3 6431 34085 21032 Mix4_TiO2_Reinj_1_3 6431 Q7Z434 Q7Z434 Q7Z434 >sp|Q7Z434|MAVS_HUMAN Mitochondrial antiviral-signaling protein OS=Homo sapiens GN=MAVS PE=1 SV=2 0.267033 0 0 0 0.267033 0 1.04526E-12 125.15 1 T SVVSTGTSFSSSS CK1;FHA KAPP 0.081 1.04526E-12 125.15 _LPGPTGSVVSTGpTSFSSSSPGLASAGAAEGK_ LPGPT(0.001)GS(0.001)VVS(0.214)T(0.214)GT(0.267)S(0.267)FS(0.037)SSSPGLASAGAAEGK LPGPT(-25.67)GS(-24.75)VVS(-0.97)T(-0.97)GT(0)S(0)FS(-8.6)S(-31.64)S(-46.49)S(-67.13)PGLAS(-107.74)AGAAEGK 13 3 948.78148 0.53503 0 0 0 0 0 0 0 0 3243 1169 2889 2889 252 289 2494 1576 Mix4_InSol_Tio2_Reinj_1 4927 2495 1578 Mix4_TiO2_1_1 3722 Q7Z6Z7;Q7Z6Z7-2;Q7Z6Z7-3 Q7Z6Z7 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3;>sp|Q7Z6Z7-2|HUWE1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1;>sp|Q7Z6Z7-3|HUWE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase H 0.513688 3.24814 0.120832 -7.9768 9.12677E-07 114.05 0.0682617 -8.34087 0.00492684 75.762 0 0 0.513688 3.24814 0.749374 24.726 1 T PRAGSSTPGDAPP CK2;FHA1 Rad53p;Polo box;Proline-directed 0.00405 9.12677E-07 114.05 _AGSSpTPGDAPPAVAEVQGR_ AGS(0.243)S(0.243)T(0.514)PGDAPPAVAEVQGR AGS(-3.25)S(-3.25)T(3.25)PGDAPPAVAEVQGR 5 2 923.92019 -0.069579 0 0 0 0 0 0 0 0 3244 1179 1426 1426 2645;5477 3008;6233 53413 32631 Mix4_TiO2_Reinj_1_1 6452 53412 32630 Mix4_TiO2_1_5 6096 Q86VI3 Q86VI3 Q86VI3 >sp|Q86VI3|IQGA3_HUMAN Ras GTPase-activating-like protein IQGAP3 OS=Homo sapiens GN=IQGAP3 PE=1 SV=2 0.572449 1.2675 0.0170362 -17.6116 2.64141E-05 128.54 0 0 0.572449 1.2675 0.00464271 79.932 0 0 0 0 0 0 1 T RRHRSLTAHSLLP CAMK2;FHA KAPP;PKA/AKT 0.001764 2.64141E-05 128.54 _SLpTAHSLLPLAEK_ S(0.428)LT(0.572)AHSLLPLAEK S(-1.27)LT(1.27)AHS(-56.67)LLPLAEK 3 2 730.38145 0.38989 245990 0 0 0 245990 0 0 0 3245 1191;1192 818;809 818 539 613 5052 3046 Mix4_TiO2_Reinj_1_5 8817 5052 3046 Mix4_TiO2_Reinj_1_5 8817 Q86YS7;Q86YS7-2 Q86YS7;Q86YS7-2 Q86YS7 >sp|Q86YS7|K0528_HUMAN Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 PE=1 SV=1;>sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 0.5 0 0.499966 0 1.04191E-07 106.42 0.5 0 1.34083E-12 131.29 1 T SLQRASTDNEELL CAMK2;CHK1;CHK1/2;CK2;PKD 0.003192 1.34083E-12 131.29 _ApSTDNEELLQFPLELCSDSLPSHPFPPAK_ AS(0.5)T(0.5)DNEELLQFPLELCSDSLPSHPFPPAK AS(0)T(0)DNEELLQFPLELCS(-121.75)DS(-121.75)LPS(-121.58)HPFPPAK 3 3 1107.1791 1.1769 1372000 54862 0 0 1317200 0 0 0 3246 1192 854 854 590 678 5607 3332 Mix4_TiO2_1_5 4625 5608 3333 Mix4_TiO2_Reinj_1_5 5381 Q86YS7-2 Q86YS7-2 Q86YS7-2 >sp|Q86YS7-2|K0528_HUMAN Isoform 2 of Uncharacterized protein KIAA0528 OS=Homo sapiens GN=KIAA0528 0.930283 11.2532 0.930283 11.2532 0.0326568 55.857 0 0 0.773589 5.33616 0.0165613 61.38 0.789681 5.746 0.0326569 55.857 0 0 1 T PAAQRATSVDYSS CK2;FHA1 Rad53p;PKA 0.042 0.0165613 61.38 _ApTSVDYSSFADR_ AT(0.93)S(0.07)VDYSSFADR AT(11.25)S(-11.25)VDY(-55.86)S(-55.86)S(-55.86)FADR 2 2 699.7823 0.65589 914210 177470 0 0 550930 0 185800 0 3247 1197 327 327 6198 7080 61429 37242 Mix4_TiO2_1_3 4291 61432 37245 Mix4_TiO2_Reinj_1_5 5114 Q8IVH8;Q8IVH8-2;Q8IVH8-3 Q8IVH8 Q8IVH8 >sp|Q8IVH8|M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3 PE=1 SV=1;>sp|Q8IVH8-2|M4K3_HUMAN Isoform 2 of Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3;>sp|Q8IVH8-3|M4K3_HUMAN 0.957872 13.569 0.957872 13.569 0.0069919 69.82 0.0184714 -17.2524 0.00208934 106.09 0 0 0 0 1 T NVREEKTRSEITF CK2 0.117 0.00208934 106.09 _pTRSEITFGQVK_ T(0.958)RS(0.042)EITFGQVK T(13.57)RS(-13.57)EIT(-47.88)FGQVK 1 2 673.32922 -0.20968 154570 154570 0 0 0 0 0 0 3248 1202 21 21 3842 4344;4345 36415 22477 Mix4_TiO2_1_5 4934 36409 22476 Mix4_TiO2_Reinj_1_1 4318 Q8IWV7;Q8IWV7-2 Q8IWV7 Q8IWV7 >sp|Q8IWV7|UBR1_HUMAN E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens GN=UBR1 PE=1 SV=1;>sp|Q8IWV7-2|UBR1_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens GN=UBR1 1 84.8102 1 84.8102 0.00292598 87.969 0 0 1 81.5903 0.00213178 91.688 0 0 0 0 1 T SAELPQTPQRLAS CDK1;CDK2;ERK/MAPK;NEK6;Proline-directed;WW GroupIV 0.0023175 0.00213178 91.688 _MEISAELPQpTPQR_ MEISAELPQT(1)PQR MEIS(-84.81)AELPQT(84.81)PQR 10 2 790.36293 0.01072 388770 85538 0 0 303230 0 0 0 3249 1206 283 283 6004 6844 59272 36015 Mix4_TiO2_1_5 3132 59272 36015 Mix4_TiO2_1_5 3132 Q8IWY9;Q8IWY9-1 Q8IWY9 Q8IWY9 >sp|Q8IWY9|CDAN1_HUMAN Codanin-1 OS=Homo sapiens GN=CDAN1 PE=1 SV=4;>sp|Q8IWY9-1|CDAN1_HUMAN Isoform 1 of Codanin-1 OS=Homo sapiens GN=CDAN1 0.882529 8.86513 0.882529 8.86513 0.0178639 63.917 1 T SPLPSRTGSLTDE FHA2 Rad53p 0.114 0.0178639 63.917 _pTGSLTDEPADPAR_ T(0.883)GS(0.115)LT(0.003)DEPADPAR T(8.87)GS(-8.87)LT(-24.89)DEPADPAR 1 2 705.30085 0.16724 31967 31967 0 0 0 0 0 0 3250 1217 463 463 1397 1570 13052 8026 Mix4_TiO2_1_3 6786 13052 8026 Mix4_TiO2_1_3 6786 Q8IY67-2;Q8IY67 Q8IY67-2 Q8IY67-2 >sp|Q8IY67-2|RAVR1_HUMAN Isoform 2 of Ribonucleoprotein PTB-binding 1 OS=Homo sapiens GN=RAVER1;>sp|Q8IY67|RAVR1_HUMAN Ribonucleoprotein PTB-binding 1 OS=Homo sapiens GN=RAVER1 PE=1 SV=1 1 69.0261 1 69.0261 0.00991413 69.026 0 0 1 T PPAAQLTPPPAPV Proline-directed 0.05 0.00991413 69.026 _EALGLGPPAAQLpTPPPAPVGLR_ EALGLGPPAAQLT(1)PPPAPVGLR EALGLGPPAAQLT(69.03)PPPAPVGLR 13 3 734.72759 -0.0083466 36337 36337 0 0 0 0 0 0 3251 1218 386 386 1257;4849 1417;5512 11844 7259 Mix4_TiO2_1_3 6986 46515 28500 Mix4_TiO2_Reinj_1_3 7387 Q8IYU2;Q8IYU2-3 Q8IYU2 Q8IYU2 >sp|Q8IYU2|HACE1_HUMAN E3 ubiquitin-protein ligase HACE1 OS=Homo sapiens GN=HACE1 PE=1 SV=2;>sp|Q8IYU2-3|HACE1_HUMAN Isoform 3 of E3 ubiquitin-protein ligase HACE1 OS=Homo sapiens GN=HACE1 0.910325 10.1219 0.910325 10.1219 0.181062 31.952 0.280554 -4.08963 1.26333E-05 139.37 1 T KNKRDSTEITSIL CAMK2;PKA 0.003024 1.26333E-05 139.37 _DSpTEITSILLK_ DS(0.089)T(0.91)EIT(0.001)S(0.001)ILLK DS(-10.12)T(10.12)EIT(-31.95)S(-31.95)ILLK 3 2 650.32581 0.93578 13743 13743 0 0 0 0 0 0 3252 1220 890 890 249 286 2485 1570 Mix4_TiO2_1_5 6132 2485 1570 Mix4_TiO2_1_5 6132 Q8IZL8-2;Q8IZL8 Q8IZL8-2 Q8IZL8-2 >sp|Q8IZL8-2|PELP1_HUMAN Isoform 2 of Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens GN=PELP1;>sp|Q8IZL8|PELP1_HUMAN Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens GN=PELP1 PE=1 SV=2 0.81325 6.41479 0.81325 6.41479 9.13797E-05 92.743 0.487953 0 0.276476 53.603 1 T ILAPSGTPPPTIP Proline-directed 0.05 9.13797E-05 92.743 _AGSNEDPILAPSGpTPPPTIPPDETFGGR_ AGSNEDPILAPS(0.186)GT(0.813)PPPT(0.001)IPPDETFGGR AGS(-84.38)NEDPILAPS(-6.41)GT(6.41)PPPT(-28.78)IPPDET(-59.47)FGGR 14 3 957.44632 0.11818 172660 172660 0 0 0 0 0 0 3253 1224 865 865 6466 7395;7396 65284 40037 Mix4_InSol_Tio2_Reinj_1 5119 65291 40045 Mix4_TiO2_Reinj_1_5 4837 Q8N122 Q8N122 Q8N122 >sp|Q8N122|RPTOR_HUMAN Regulatory-associated protein of mTOR OS=Homo sapiens GN=RPTOR PE=1 SV=1 0.938192 11.8125 0.655943 2.80235 1.94105E-26 192.47 0.214399 -5.63978 1.95966E-15 145.54 0.122691 -8.54342 3.25175E-31 198.3 0 0 0.142256 -7.80275 7.76844E-26 184.23 0.938192 11.8125 7.2337E-17 156.24 1 T SAPASPTNKGVHI 3.25175E-31 198.3 _VLDTSSLTQSAPASPpTNK_ VLDTSSLTQSAPAS(0.062)PT(0.938)NK VLDT(-143.63)S(-124.93)S(-112.2)LT(-76.75)QS(-85.13)APAS(-11.81)PT(11.81)NK 16 2 948.95115 0.39974 362380 99679 0 0 0 0 0 262700 3254 1226 766 766 3504 3957 33067 20456 Mix4_InSol_TiO2_1 2276 33067 20456 Mix4_InSol_TiO2_1 2276 Q8N1F7 Q8N1F7 Q8N1F7 >sp|Q8N1F7|NUP93_HUMAN Nuclear pore complex protein Nup93 OS=Homo sapiens GN=NUP93 PE=1 SV=2 0.952064 13.7413 0 0 0.466206 1.34651 0.150929 38.649 0.952064 13.7413 0.00511874 77.907 0.0510305 -6.59854 0.023704 60.305 1 T FKRLKGTSPSSSS FHA KAPP;NEK6 0.076 0.00511874 77.907 _LKGpTSPSSSSRPQR_ LKGT(0.952)S(0.001)PS(0.04)S(0.007)SSRPQR LKGT(13.74)S(-30.46)PS(-13.74)S(-21.57)S(-36.79)S(-47.62)RPQR 4 2 784.38304 -0.31096 642550 0 0 0 0 0 642550 0 3255 1229 83 83 3746 4226 35415 21887 Mix4_TiO2_Reinj_1_1 5590 35415 21887 Mix4_TiO2_Reinj_1_1 5590 Q8N201 Q8N201 Q8N201 >sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 0.977439 16.4765 0.644883 2.72437 0.0454707 52.23 0 0 0.977439 16.4765 0.00804348 76.766 0 0 0 0 0 0 1 T RPKLSSTPPLSAL FHA2 Rad53p;NEK6;Polo box;Proline-directed 0.00405 0.00804348 76.766 _LSSpTPPLSALGR_ LS(0.001)S(0.022)T(0.977)PPLSALGR LS(-32.47)S(-16.48)T(16.48)PPLS(-52.18)ALGR 4 2 639.82631 0.095967 280810 45504 0 0 235310 0 0 0 3256 1234 363 363 3542 3995 33415 20622 Mix4_TiO2_Reinj_1_2 4002 33415 20622 Mix4_TiO2_Reinj_1_2 4002 Q8N357 Q8N357 Q8N357 >sp|Q8N357|CB018_HUMAN Transmembrane protein C2orf18 OS=Homo sapiens GN=C2orf18 PE=1 SV=1 0.914339 10.2833 0.503056 0.0544381 0.00842588 75.129 0.447117 2.08817 0.356459 13.263 0.914339 10.2833 0.00429976 81.538 0 0 0.00510743 -22.8884 0.303911 27.738 0 0 1 T ERLLGGTRTPIND NEK6 0.076 0.00429976 81.538 _LLGGpTRTPINDAS_ LLGGT(0.914)RT(0.086)PINDAS LLGGT(10.28)RT(-10.28)PINDAS(-71.96) 5 2 697.83741 -0.5633 374290 26137 0 0 348150 0 0 0 3257 1234 365 365 3542 3995 33408 20614 Mix4_InSol_TiO2_1 4971 33415 20622 Mix4_TiO2_Reinj_1_2 4002 Q8N357 Q8N357 Q8N357 >sp|Q8N357|CB018_HUMAN Transmembrane protein C2orf18 OS=Homo sapiens GN=C2orf18 PE=1 SV=1 0.993221 22.8884 0.964863 14.387 0.00842588 75.129 0.686468 3.87682 0.356459 13.263 0.990801 23.2919 0.00429976 81.538 0 0 0.993221 22.8884 0.303911 27.738 0 0 1 T LLGGTRTPINDAS Proline-directed 0.05 0.00429976 81.538 _LLGGTRpTPINDAS_ LLGGT(0.005)RT(0.993)PINDAS(0.002) LLGGT(-22.89)RT(22.89)PINDAS(-27.74) 7 2 697.83741 -0.0054227 388180 132840 12442 0 138560 0 104350 0 3258 1237 715 715 2498;2499 2838;2839 23509 14618 Mix4_InSol_Tio2_Reinj_1 4786 23503 14616 Mix4_TiO2_Reinj_1_5 4730 Q8N4C8 Q8N4C8 Q8N4C8 >sp|Q8N4C8|MINK1_HUMAN Misshapen-like kinase 1 OS=Homo sapiens GN=MINK1 PE=1 SV=2 0.694824 4.80749 1.19651E-08 -76.6622 0.00372107 76.662 0 0 3.18831E-05 -44.7691 0.000312387 85.631 0.0196511 -16.1962 0.0093242 71.719 0.694824 4.80749 1.04263 33.038 1 T RRAERGTPKPPGP CDK1;PKA;Proline-directed 0.0057 0.000312387 85.631 _GpTPKPPGPPAQPPGPPNASSNPDLRR_ GT(0.695)PKPPGPPAQPPGPPNAS(0.075)S(0.23)NPDLRR GT(4.81)PKPPGPPAQPPGPPNAS(-9.64)S(-4.81)NPDLRR 2 3 894.77645 0.63056 92357 0 0 0 0 0 0 92357 3259 1272 8362 8362 5406 6153 52701 32212 Mix4_TiO2_Reinj_1_1 3888 52698 32209 Mix4_TiO2_1_1 3366 Q8NF91;Q8NF91-4;Q8NF91-2;Q8NF91-8;Q8NF91-3;Q8NF91-9 Q8NF91 Q8NF91 >sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3;>sp|Q8NF91-4|SYNE1_HUMAN Isoform 4 of Nesprin-1 OS=Homo sapiens GN=SYNE1;>sp|Q8NF91-2|SYNE1_HUMAN Isoform Beta of Nesprin-1 OS=Homo sapiens GN=SYNE1;>sp|Q8NF91-8|SYNE1_HUMAN Isoform Beta 2 0.688254 3.44454 0.445237 2.06109 1.36376E-06 123.14 0 0 0.688254 3.44454 7.9658E-06 117.55 0 0 0 0 0 0 1 T IRSKTPTGPELDT CK2 0.117 1.36376E-06 123.14 _SKTPpTGPELDTSYK_ SKT(0.311)PT(0.688)GPELDTSYK S(-32.78)KT(-3.44)PT(3.44)GPELDT(-96.64)S(-96.64)Y(-96.64)K 5 3 535.24655 0.32734 109020 0 0 0 109020 0 0 0 3260 1296 842 842 1653 1856;1858 15241 9198 Mix4_TiO2_Reinj_2_1 5413 15239 9196 Mix4_TiO2_Reinj_1_6 7597 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.193492 0 0.038848 -8.7627 0.271442 65.199 0.0539554 -6.1111 0.270434 65.253 0.0546174 -10.6546 2.75295E-11 125.74 0.193492 0 0.0354649 77.845 1 T SESEKDTLPYEEL AURORA;AURORA-1 0.020748 2.75295E-11 125.74 _ELENAEFIPM(ox)PDSPSPLpSAAFSESEKDTLPYEELQGLK_ ELENAEFIPMPDS(0.01)PS(0.042)PLS(0.193)AAFS(0.193)ES(0.193)EKDT(0.193)LPY(0.175)EELQGLK ELENAEFIPMPDS(-13.03)PS(-6.65)PLS(0)AAFS(0)ES(0)EKDT(0)LPY(-0.45)EELQGLK 28 4 1076.9985 0.096099 0 0 0 0 0 0 0 0 0 3261 1296 883 883 2500 2840 23521 14627 Mix4_InSol_Tio2_Reinj_1 6765 23517 14623 Mix4_InSol_TiO2_1 6847 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.550623 0.88245 0.5 0 3.76089E-11 134.1 0.236057 -5.10038 0.0263443 59.264 0.0652262 -11.5622 1.33498E-21 158.47 0.229546 -1.32398 1.75406 1.324 0.54993 0.879502 2.2019E-26 176.02 0.550623 0.88245 0.000103358 96.006 1 T TCAGKGTPLTPPA Proline-directed 0.05 2.2019E-26 176.02 _GpTPLTPPACACSSLQVEVER_ GT(0.551)PLT(0.449)PPACACSSLQVEVER GT(0.88)PLT(-0.88)PPACACS(-56.3)S(-64.69)LQVEVER 2 2 1126.508 -0.35493 484140 27265 0 0 0 0 169700 287170 3262 1296 886 886 2500 2840 23517 14623 Mix4_InSol_TiO2_1 6847 23517 14623 Mix4_InSol_TiO2_1 6847 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.995597 23.5436 0.968275 14.8459 3.76089E-11 134.1 0.763932 5.10038 0.0263443 59.264 0.993295 23.0932 1.33498E-21 158.47 0.311363 1.32398 1.75406 1.324 0.995597 23.5436 2.2019E-26 176.02 0.944574 12.6279 0.000103358 96.006 1 T GKGTPLTPPACAC ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 2.2019E-26 176.02 _GTPLpTPPACACSSLQVEVER_ GT(0.004)PLT(0.996)PPACACSSLQVEVER GT(-23.54)PLT(23.54)PPACACS(-87.81)S(-94.63)LQVEVER 5 2 1126.508 -0.10274 4649400 262720 46210 0 3590000 0 654950 95490 3263 1296 333 333 4999;5765 5685;6569 56720 34600 Mix4_InSol_TiO2_2 4944 56730 34614 Mix4_TiO2_1_5 5362 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.37254 0 0.370535 0 1.37711E-16 190.81 0.0669323 -9.14325 0.00254408 82.191 0.298516 -1.30256 3.97906E-13 175.31 0 0 0.37254 0 4.18384E-16 181.82 0.369444 0 6.41205E-12 165.91 1 T KRPRSSTVTEAPI CAMK2;CK2;PKA/AKT 0.00111111 1.37711E-16 190.81 _SpSTVTEAPIAVVTSR_ S(0.255)S(0.373)T(0.373)VTEAPIAVVTSR S(-1.65)S(0)T(0)VT(-39.26)EAPIAVVT(-91.58)S(-91.58)R 3 2 799.39528 0.093537 0 0 0 0 0 0 0 0 0 3264 1296 358 358 5797;6214 6603;7098 57107 34833 Mix4_TiO2_Reinj_1_5 4554 61577 37328 Mix4_InSol_TiO2_1 7141 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.78633 5.65861 0.585988 1.50875 0.150398 33.896 0.78633 5.65861 0.21678 28.396 0.5 0 0.000255897 89.991 0 0 1 T WGGGKSTPQKLDV CDK1;CDK2;Polo box;Proline-directed 0.00405 0.000255897 89.991 _SpTPQKLDVIK_ S(0.214)T(0.786)PQKLDVIK S(-5.66)T(5.66)PQKLDVIK 2 3 403.54773 -0.10782 1467300 295040 0 0 1083000 0 89325 0 3265 1296 254 254 5984 6824 59137 35922 Mix4_TiO2_1_5 6869 59137 35922 Mix4_TiO2_1_5 6869 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.996773 24.8974 0.996773 24.8974 0.0036035 84.821 0 0 1 T KRTFDATNPLNLC FHA2 Rad53p 0.114 0.0036035 84.821 _TFDApTNPLNLCVK_ T(0.003)FDAT(0.997)NPLNLCVK T(-24.9)FDAT(24.9)NPLNLCVK 5 2 786.86002 0.70778 52190 52190 0 0 0 0 0 0 3266 1307 371 371 2212 2505 20275 12452 Mix4_TiO2_Reinj_1_5 2426 20275 12452 Mix4_TiO2_Reinj_1_5 2426 Q8TER5;Q8TER5-3;Q8TER5-4 Q8TER5 Q8TER5 >sp|Q8TER5|SOLO_HUMAN Protein SOLO OS=Homo sapiens GN=SOLO PE=1 SV=3;>sp|Q8TER5-3|SOLO_HUMAN Isoform 3 of Protein SOLO OS=Homo sapiens GN=SOLO;>sp|Q8TER5-4|SOLO_HUMAN Isoform 4 of Protein SOLO OS=Homo sapiens GN=SOLO 1 153.37 1 78.3088 0.00343457 78.309 1 153.37 2.90099E-13 153.37 1 138.898 1.56753E-12 138.9 1 71.9319 0.0108749 71.932 1 T AEGPPGTPRRTGK CDK1;CDK2;ERK/MAPK;Proline-directed 0.0025 2.90099E-13 153.37 _GGGGGGQGAEGPPGpTPR_ GGGGGGQGAEGPPGT(1)PR GGGGGGQGAEGPPGT(153.37)PR 15 2 744.81499 0.19052 210220 22074 0 0 105040 0 42868 40241 3267 1310 456 456 1667 1873 15320 9246 Mix4_TiO2_Reinj_1_5 8757 15319 9244 Mix4_TiO2_Reinj_1_3 8978 Q8WTW3 Q8WTW3 Q8WTW3 >sp|Q8WTW3|COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens GN=COG1 PE=1 SV=1 0.282407 0 0.0387419 -12.476 1.41405E-23 157.8 0.282407 0 6.23324E-66 270.69 1 T QELESSTSNSPSN FHA KAPP 0.155 6.23324E-66 270.69 _ELLVSALQELESpSTSNSPSNK_ ELLVSALQELESS(0.282)T(0.282)S(0.282)NS(0.152)PSNK ELLVS(-73.49)ALQELES(-28.27)S(0)T(0)S(0)NS(-2.68)PS(-37.66)NK 14 3 771.7001 -0.062388 0 0 0 0 0 0 0 0 0 3268 1311 663 663 4056 4622 38359 23518 Mix4_InSol_Tio2_Reinj_1 5203 38357 23516 Mix4_InSol_TiO2_1 5288 Q8WU17 Q8WU17 Q8WU17 >sp|Q8WU17|RN139_HUMAN E3 ubiquitin-protein ligase RNF139 OS=Homo sapiens GN=RNF139 PE=1 SV=1 1 173.046 0 0 0 0 1 234.165 8.5219E-48 234.17 1 173.046 7.75082E-22 173.05 1 T EEFNDDTD_____ 8.5219E-48 234.17 _NGVIQHTGAAAEEFNDDpTD_ NGVIQHTGAAAEEFNDDT(1)D NGVIQHT(-173.05)GAAAEEFNDDT(173.05)D 18 2 1042.4157 -0.24973 347980 0 0 0 0 0 223110 124880 3269 1320 683 683 5806 6618 57242 34888 Mix4_TiO2_Reinj_1_1 1803 57243 34889 Mix4_TiO2_Reinj_1_5 2180 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.827539 6.82071 0.46634 -0.585537 0.0308764 54.307 0.524342 0.458109 0.234141 27.409 0.827539 6.82071 0.00362774 78.096 0.596014 1.68977 0.0429911 44.679 0.08625 -8.19162 0.0199227 54.307 1 T KSTSTPTSPGPRT CK1 0.081 0.00362774 78.096 _STSTPpTSPGPR_ STSTPT(0.828)S(0.172)PGPR S(-39.33)T(-39.33)S(-39.33)T(-39.33)PT(6.82)S(-6.82)PGPR 6 2 584.25572 0.20575 1002700 0 34637 0 968050 0 0 0 3270 1320 421 421 6094 6955 60251 36477 Mix4_TiO2_1_5 4089 60252 36478 Mix4_TiO2_Reinj_1_5 4701 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.243357 0 0.243357 0 0.282943 40.597 0.0738981 -7.58768 0.0106388 68.652 1 T PLRGAKTLSSPSN FHA KAPP 0.155 0.0106388 68.652 _pTLSSPSNRPSGETSVPPPPAVGR_ T(0.243)LS(0.243)S(0.243)PS(0.243)NRPS(0.017)GET(0.005)S(0.005)VPPPPAVGR T(0)LS(0)S(0)PS(0)NRPS(-11.55)GET(-17.08)S(-17.08)VPPPPAVGR 1 3 790.71983 0.43978 0 0 0 0 0 0 0 0 3271 1321 564 564 3163 3590 30008 18655 Mix4_TiO2_Reinj_1_4 8875 30007 18654 Mix4_TiO2_Reinj_1_3 9028 Q8WX92 Q8WX92 Q8WX92 >sp|Q8WX92|NELFB_HUMAN Negative elongation factor B OS=Homo sapiens GN=COBRA1 PE=1 SV=1 0.59438 1.65946 0.116291 -8.80764 0.00566061 75.286 0.59438 1.65946 0.000148232 90.506 1 T PAQAAETPALELP FHA2 Rad53p;Proline-directed 0.05 0.000148232 90.506 _KPSPAQAAEpTPALELPLPSVPAPAPL_ KPS(0.406)PAQAAET(0.594)PALELPLPSVPAPAPL KPS(-1.66)PAQAAET(1.66)PALELPLPS(-55.66)VPAPAPL 10 3 881.46622 0.82814 191570 0 0 0 191570 0 0 0 3272 1328 26499 26499 1878 2121 17273 10385 Mix4_TiO2_Reinj_1_2 6973 17273 10385 Mix4_TiO2_Reinj_1_2 6973 Q8WZ42-8;Q8WZ42;Q8WZ42-2;Q8WZ42-7;Q8WZ42-4;Q8WZ42-5;Q8WZ42-3 Q8WZ42-8 Q8WZ42-8 >sp|Q8WZ42-8|TITIN_HUMAN Isoform Cardiac novex-1 of Titin OS=Homo sapiens GN=TTN;>sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens GN=TTN PE=1 SV=2;>sp|Q8WZ42-2|TITIN_HUMAN Isoform 2 of Titin OS=Homo sapiens GN=TTN;>sp|Q8WZ42-7|TITIN_HUMAN Isoform Cardiac novex 0.498668 0 0.498668 0 0.0109083 69.801 1 T NVSSSKTVTSLSI CK1;FHA KAPP 0.081 0.0109083 69.801 _ETTRVNVSSpSKTVTSLSIK_ ETTRVNVSSS(0.499)KT(0.499)VTSLS(0.001)IK ET(-59.55)T(-59.55)RVNVS(-30.06)S(-30.96)S(0)KT(0)VT(-30.02)S(-30.02)LS(-28.07)IK 12 2 1059.0461 1.3097 0 0 0 0 0 0 0 0 3273 1329 245 245 4815 5465 45959 28105 Mix4_TiO2_Reinj_1_4 8594 45959 28105 Mix4_TiO2_Reinj_1_4 8594 Q8WZ73;Q8WZ73-2;Q8WZ73-3 Q8WZ73 Q8WZ73 >sp|Q8WZ73|RFFL_HUMAN E3 ubiquitin-protein ligase rififylin OS=Homo sapiens GN=RFFL PE=1 SV=1;>sp|Q8WZ73-2|RFFL_HUMAN Isoform 2 of E3 ubiquitin-protein ligase rififylin OS=Homo sapiens GN=RFFL;>sp|Q8WZ73-3|RFFL_HUMAN Isoform 3 of E3 ubiquitin-protein ligas 0.466973 2.43573 0 0 0.466973 2.43573 0.00050672 90.244 1 T ASLSDLTDLEDIE CK1;CK2 0.081 0.00050672 90.244 _RASLSDLpTDLEDIEGLTVR_ RAS(0.267)LS(0.267)DLT(0.467)DLEDIEGLTVR RAS(-2.44)LS(-2.44)DLT(2.44)DLEDIEGLT(-90.24)VR 8 3 728.3579 -0.61996 0 0 0 0 0 0 0 0 3274 1335 40 40 5793 6599 57078 34818 Mix4_TiO2_Reinj_1_5 5360 57078 34818 Mix4_TiO2_Reinj_1_5 5360 Q92521 Q92521 Q92521 >sp|Q92521|PIGB_HUMAN GPI mannosyltransferase 3 OS=Homo sapiens GN=PIGB PE=2 SV=1 0.614421 2.02353 0.590953 1.59921 0.0828335 39.495 0.614421 2.02353 0.00569159 64.304 1 T LRKRKSTLYFNTQ AURORA;AURORA-1;AURORA-A;CAMK2;PKA;PKA/AKT 0.001764 0.00569159 64.304 _SpTLYFNTQEK_ S(0.386)T(0.614)LYFNTQEK S(-2.02)T(2.02)LY(-64.3)FNT(-64.3)QEK 2 2 655.78685 0.27212 209730 22990 0 0 186740 0 0 0 3275 1337 1317 1317 2549;2550 2894;2895 23852 14806 Mix4_TiO2_1_1 3154 23859 14817 Mix4_TiO2_Reinj_1_5 4020 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.869195 8.59083 0.869195 8.59083 0.00384171 79.117 0 0 0.590266 1.59588 2.70746E-09 130.01 0 0 0.00505339 -22.8164 0.47153 30.785 0.0189294 -16.9603 0.574289 27.487 1 T SLDRGYTSDSEVY CAMK2;CHK1;CHK1/2;FHA KAPP;PKD 0.003192 2.70746E-09 130.01 _GYpTSDSEVYTDHGRPGK_ GY(0.01)T(0.869)S(0.12)DS(0.001)EVYTDHGRPGK GY(-19.45)T(8.59)S(-8.59)DS(-30.92)EVY(-68.5)T(-62.7)DHGRPGK 3 2 974.90728 0.19808 2123000 76001 0 0 2047000 0 0 0 3276 1345 1786 1786 3732 4209 35208 21783 Mix4_TiO2_1_5 5526 35209 21784 Mix4_TiO2_Reinj_1_5 6396 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.68948 4.07344 0.68948 4.07344 0.414608 12.296 0.188775 -5.1816 0.0199625 63.873 1 T SPRLSQTFLQLSD NEK6 0.076 0.0199625 63.873 _LSQpTFLQLSDGDKK_ LS(0.27)QT(0.689)FLQLS(0.041)DGDKK LS(-4.07)QT(4.07)FLQLS(-12.3)DGDKK 4 2 830.40311 -0.051732 0 0 0 0 0 0 0 0 3277 1345 1689 1689 6394 7315 64601 39625 Mix4_InSol_TiO2_2 4746 64605 39629 Mix4_TiO2_1_5 5153 Q92608 Q92608 Q92608 >sp|Q92608|DOCK2_HUMAN Dedicator of cytokinesis protein 2 OS=Homo sapiens GN=DOCK2 PE=1 SV=2 0.395317 0 0.000419698 -33.7576 8.00572E-43 234.15 0.00021241 -36.7223 6.85463E-06 105.13 0.000360656 -34.4175 6.00993E-36 233.71 0.395317 0 1.86071E-16 168.91 0.149044 -6.7297 7.63881E-06 103.64 1 T PISPGSTLPEVKL CK2 0.117 8.00572E-43 234.15 _VEQEEPISPGpSTLPEVK_ VEQEEPIS(0.209)PGS(0.395)T(0.395)LPEVK VEQEEPIS(-2.76)PGS(0)T(0)LPEVK 12 2 959.9559 -0.24731 0 0 0 0 0 0 0 0 0 3278 1346 560 560 1524;1525 1713;1714;1715 14072 8580 Mix4_TiO2_Reinj_1_5 3138 14051 8571 Mix4_TiO2_Reinj_1_3 3375 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.379896 0 0.0729062 -8.03284 0.0768905 45.038 0 0 0.379896 0 0.0137825 66.4 0.00383559 -23.5646 0.15476 37.035 0.00165107 -25.4856 0.280455 29.2 1 T SPPSSATKKDSFF CK1;CK2;FHA1 Rad53p 0.059 0.0137825 66.4 _EFTGSPPSpSATKK_ EFT(0.003)GS(0.119)PPS(0.119)S(0.38)AT(0.38)KK EFT(-21.02)GS(-5.06)PPS(-5.06)S(0)AT(0)KK 11 2 708.82396 0.081495 0 0 0 0 0 0 0 0 3279 1346 42 42 5061;6246 5755;7136 48936 29898 Mix4_InSol_Tio2_Reinj_1 5481 48940 29902 Mix4_TiO2_Reinj_1_3 5147 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.675336 4.50726 0.450444 0 0.000424469 95.611 0.437525 0 1.03037E-15 158.33 0.195377 -1.78631 0.614703 24.686 0.675336 4.50726 0.00164998 86.019 1 T NKNGRRTSSTLDS PKA 0.042 1.03037E-15 158.33 _RpTSSTLDSEGTFNSYR_ RT(0.675)S(0.239)S(0.085)T(0.001)LDSEGTFNSYR RT(4.51)S(-4.51)S(-9.02)T(-29.72)LDS(-62.52)EGT(-79.58)FNS(-86.02)Y(-86.02)R 2 2 950.90728 0.15395 80690 0 0 0 0 0 0 80690 3280 1346 45 45 5061;6246 5755;7136 48940 29902 Mix4_TiO2_Reinj_1_3 5147 48940 29902 Mix4_TiO2_Reinj_1_3 5147 Q92609 Q92609 Q92609 >sp|Q92609|TBCD5_HUMAN TBC1 domain family member 5 OS=Homo sapiens GN=TBC1D5 PE=1 SV=1 0.424034 0 0.0900559 -6.58037 0.000424469 95.611 0.424034 0 1.03037E-15 158.33 0.294784 0 0.614703 24.686 0.000720618 -29.7181 0.00164998 86.019 1 T GRRTSSTLDSEGT FHA KAPP 0.155 1.03037E-15 158.33 _RTSpSTLDSEGTFNSYR_ RT(0.001)S(0.149)S(0.424)T(0.424)LDS(0.002)EGTFNSYR RT(-25.88)S(-4.54)S(0)T(0)LDS(-23.92)EGT(-103.56)FNS(-158.33)Y(-158.33)R 5 3 634.27394 -0.24127 0 0 0 0 0 0 0 0 3281 1352 44 44 5341 6082 51868 31750 Mix4_TiO2_2_4 5950 51867 31748 Mix4_TiO2_1_3 6457 Q92630 Q92630 Q92630 >sp|Q92630|DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2 PE=1 SV=3 0.972457 17.7742 0.654686 2.78065 4.12467E-06 110.28 0.972457 17.7742 0.0821277 51.856 0.496669 0 0.000535578 93.769 1 T TRSGVGTGPPSPI 4.12467E-06 110.28 _SGVGpTGPPSPIALPPLR_ S(0.011)GVGT(0.972)GPPS(0.016)PIALPPLR S(-19.34)GVGT(17.77)GPPS(-17.77)PIALPPLR 5 2 848.44511 0.33665 349640 306690 42950 0 0 0 0 0 3282 1356 244 244 3198 3628 30344 18881 Mix4_TiO2_Reinj_1_6 1074 30344 18881 Mix4_TiO2_Reinj_1_6 1074 Q92688 Q92688 Q92688 >sp|Q92688|AN32B_HUMAN Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens GN=ANP32B PE=1 SV=1 1 143.138 1 51.7236 0.0395873 51.724 1 143.138 0.000166452 143.14 1 127.142 0.00189274 127.14 1 98.1564 0.00137542 98.156 1 T EKRKRETDDEGED CK2;PKA 0.042 0.000166452 143.14 _KREpTDDEGEDD_ KRET(1)DDEGEDD KRET(143.14)DDEGEDD 4 2 694.74611 0.43653 308180 15257 0 0 33249 0 113830 145840 3283 1361 213 213 2105 2384 19274 11701 Mix4_InSol_Tio2_Reinj_1 4599 19274 11701 Mix4_InSol_Tio2_Reinj_1 4599 Q92844 Q92844 Q92844 >sp|Q92844|TANK_HUMAN TRAF family member-associated NF-kappa-B activator OS=Homo sapiens GN=TANK PE=1 SV=2 0.999969 45.1622 0.98752 19.7875 0.201179 30.23 0.916637 10.8843 0.00801778 67.296 0.99976 38.5582 0.00970197 63.152 0.999969 45.1622 0.00319442 116.53 1 T PSITSVTPRGLCR CDK1;Proline-directed 0.0057 0.00319442 116.53 _GAPSITSVpTPR_ GAPSITSVT(1)PR GAPS(-106.63)IT(-63.13)S(-45.16)VT(45.16)PR 9 2 583.28428 -0.60009 166300 48959 37667 0 0 0 25585 54087 3284 1361 224 224 2300 2602 21289 13050 Mix4_InSol_Tio2_Reinj_1 5581 21289 13050 Mix4_InSol_Tio2_Reinj_1 5581 Q92844 Q92844 Q92844 >sp|Q92844|TANK_HUMAN TRAF family member-associated NF-kappa-B activator OS=Homo sapiens GN=TANK PE=1 SV=2 0.722084 4.34851 0.0740889 -10.9516 0.00200375 83.25 0.616621 2.06401 0.00206459 82.773 0.14426 -7.72453 5.48078E-06 110.43 0.722084 4.34851 4.44392E-06 111.88 1 T CRDEEDTSFESLS CK2 0.117 4.44392E-06 111.88 _GLCRDEEDpTSFESLSK_ GLCRDEEDT(0.722)S(0.265)FES(0.013)LSK GLCRDEEDT(4.35)S(-4.35)FES(-17.58)LS(-72.05)K 9 2 976.9008 -0.24737 458940 0 0 0 295550 0 0 163390 3285 1365 100 100 2765;2766 3153;3155 26409 16524 Mix4_TiO2_1_3 5558 26408 16523 Mix4_TiO2_1_3 5542 Q92945;Q92945-2 Q92945 Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP PE=1 SV=3;>sp|Q92945-2|FUBP2_HUMAN Isoform 2 of Far upstream element-binding protein 2 OS=Homo sapiens GN=KHSRP 0.958456 13.6307 0.958456 13.6307 3.18618E-24 168.76 0 0 0.331625 -3.04373 1.20455E-07 115.74 0.908755 10.0351 6.5829E-07 105.17 0.474217 0 0.000430572 85.948 1 T TTVNNSTPDFGFG Polo box;Proline-directed 0.00405 3.18618E-24 168.76 _IGGDAATTVNNSpTPDFGFGGQK_ IGGDAATTVNNS(0.042)T(0.958)PDFGFGGQK IGGDAAT(-88.3)T(-67.15)VNNS(-13.63)T(13.63)PDFGFGGQK 13 3 745.33023 1.7262 557640 0.19654 377570 0 0 0 0 180070 0 3286 1367 175 175 2839 3233 27113 16955 Mix4_InSol_TiO2_1 5740 27113 16955 Mix4_InSol_TiO2_1 5740 Q92974;Q92974-2;Q92974-3 Q92974 Q92974 >sp|Q92974|ARHG2_HUMAN Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2 PE=1 SV=4;>sp|Q92974-2|ARHG2_HUMAN Isoform 2 of Rho guanine nucleotide exchange factor 2 OS=Homo sapiens GN=ARHGEF2;>sp|Q92974-3|ARHG2_HUMAN Isoform 3 of Rho guanine 0.592329 1.68189 0 0 0 0 0.592329 1.68189 0.0130995 67.633 0 0 1 T RILSQSTDSLNMR CK1;FHA2 Rad53p 0.081 0.0130995 67.633 _ILSQSpTDSLNMR_ ILS(0.005)QS(0.402)T(0.592)DSLNMR ILS(-20.44)QS(-1.68)T(1.68)DS(-35.02)LNMR 6 2 722.82872 -0.19761 75883 0 0 0 0 0 75883 0 3287 1368 2560 2560 423;424 483;485 3975 2370 Mix4_TiO2_Reinj_1_1 3352 3972 2363 Mix4_InSol_Tio2_Reinj_1 4056 Q93008-2;Q93008 Q93008-2 Q93008-2 >sp|Q93008-2|USP9X_HUMAN Isoform Long of Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens GN=USP9X;>sp|Q93008|USP9X_HUMAN Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens GN=USP9X PE=1 SV=2 0.923502 10.8179 0.00107745 -29.6714 3.41234E-20 179.58 0.687516 3.45626 0.563358 27.816 0.923502 10.8179 1.72043E-16 169.42 0 0 0.631771 2.34442 1.53173E-15 142.3 0.188406 -6.34244 1.06641E-20 190.32 1 T EVSPPQTKDQ___ 1.06641E-20 190.32 _AQENYEGSEEVSPPQpTK_ AQENYEGSEEVS(0.076)PPQT(0.924)K AQENY(-132.92)EGS(-77.72)EEVS(-10.82)PPQT(10.82)K 16 2 986.91222 0.70292 851480 0.30064 0 10244 0 710520 0 130720 0 3288 1371 695 695 4746;5015 5392;5703;5704 48448 29643 Mix4_TiO2_1_3 6168 48449 29644 Mix4_TiO2_1_5 6016 Q93100-2;Q93100-4;Q93100;Q93100-3 Q93100-2 Q93100-2 >sp|Q93100-2|KPBB_HUMAN Isoform 2 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100-4|KPBB_HUMAN Isoform 4 of Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens GN=PHKB;>sp|Q93100|KPBB_HUMAN Phosphorylase b ki 0.780228 8.14695 0.780228 8.14695 1.20866E-17 151.47 0 0 0.75026 9.54846 1.19067E-11 131.09 0.325441 0 0.0173895 60.584 0.106435 -6.17656 0.0140872 64.313 1 T VKRQSSTPSAPEL FHA KAPP;Polo box;Proline-directed 0.00405 1.20866E-17 151.47 _RQSSpTPSAPELGQQPDVNISEWK_ RQS(0.042)S(0.12)T(0.78)PS(0.058)APELGQQPDVNISEWK RQS(-12.7)S(-8.15)T(8.15)PS(-11.27)APELGQQPDVNIS(-108.8)EWK 5 3 878.7447 0.5505 2856600 995800 0 0 1860800 0 0 0 3289 1380 629 629 4684 5316;5317 44513 27307 Mix4_TiO2_1_4 3753 44527 27313 Mix4_InSol_TiO2_1 5193 Q96AE4 Q96AE4 Q96AE4 >sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 PE=1 SV=3 0.634161 2.38942 0.634161 2.38942 9.14443E-18 145.46 0.499836 0 6.70951E-12 132.32 0.598862 1.74041 4.88931E-18 150.68 0.52165 1.184 1.80836E-07 113.89 1 T AAYYAQTSPQGMP 4.88931E-18 150.68 _QQAAYYAQpTSPQGM(ox)PQHPPAPQGQ_ QQAAYYAQT(0.634)S(0.366)PQGMPQHPPAPQGQ QQAAY(-64.59)Y(-43.56)AQT(2.39)S(-2.39)PQGMPQHPPAPQGQ 9 3 893.05488 0.21556 10140000 0.15548 225540 0 0 0 0 2640500 7273700 3290 1380 151 151 5135;5136 5841;5842;5845;5846 49695 30353 Mix4_InSol_Tio2_Reinj_1 3924 49666 30344 Mix4_InSol_Tio2_Reinj_1 4895 Q96AE4;Q96AE4-2 Q96AE4 Q96AE4 >sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 PE=1 SV=3;>sp|Q96AE4-2|FUBP1_HUMAN Isoform 2 of Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 0.491042 0 4.73977E-05 -42.1729 4.97756E-07 123.83 0 0 0.00530591 -22.5806 3.24335E-24 214.38 0.491042 0 4.19624E-30 222.38 1 T ERSCMLTGTPESV 4.19624E-30 222.38 _SCM(ox)LpTGTPESVQSAKR_ S(0.017)CMLT(0.491)GT(0.491)PES(0.001)VQSAKR S(-14.63)CMLT(0)GT(0)PES(-29.62)VQS(-30.17)AKR 5 2 924.405 -0.50487 0 0 0 0 0 0 0 0 0 3291 1380 153 153 5135;5136 5841;5842;5845;5846 49666 30344 Mix4_InSol_Tio2_Reinj_1 4895 49666 30344 Mix4_InSol_Tio2_Reinj_1 4895 Q96AE4;Q96AE4-2 Q96AE4 Q96AE4 >sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 PE=1 SV=3;>sp|Q96AE4-2|FUBP1_HUMAN Isoform 2 of Far upstream element-binding protein 1 OS=Homo sapiens GN=FUBP1 0.99998 49.9121 0.781705 5.54094 4.97756E-07 123.83 0 0 0.999503 33.2287 3.24335E-24 214.38 0.99998 49.9121 4.19624E-30 222.38 1 T SCMLTGTPESVQS FHA KAPP;NEK6;Proline-directed 0.05 4.19624E-30 222.38 _SCMLTGpTPESVQSAK_ SCMLTGT(1)PESVQSAK S(-106.18)CMLT(-49.91)GT(49.91)PES(-49.91)VQS(-135.11)AK 7 2 838.35699 -0.25187 1292500 5.4376 63370 0 0 0 0 655110 574050 3292 1381 35 35 5276 6004 51209 31381 Mix4_TiO2_1_4 7062 51210 31382 Mix4_TiO2_Reinj_1_4 7471 Q96AG3 Q96AG3 Q96AG3 >sp|Q96AG3|S2546_HUMAN Solute carrier family 25 member 46 OS=Homo sapiens GN=SLC25A46 PE=1 SV=1 0.25952 0 0.25952 0 4.91125E-11 120.79 0.137403 -7.13755 6.87413E-12 135.07 1 T PARSFSTGSDLGH CK1;CK2;FHA1 Rad53p 0.059 6.87413E-12 135.07 _SFpSTGSDLGHWVTTPPDIPGSR_ S(0.221)FS(0.26)T(0.26)GS(0.26)DLGHWVT(0.001)TPPDIPGSR S(-0.7)FS(0)T(0)GS(0)DLGHWVT(-26.69)T(-46.12)PPDIPGS(-46.12)R 4 3 798.69691 -0.096364 0 0 0 0 0 0 0 0 3293 1381 45 45 5276 6004 51210 31382 Mix4_TiO2_Reinj_1_4 7471 51210 31382 Mix4_TiO2_Reinj_1_4 7471 Q96AG3 Q96AG3 Q96AG3 >sp|Q96AG3|S2546_HUMAN Solute carrier family 25 member 46 OS=Homo sapiens GN=SLC25A46 PE=1 SV=1 0.998292 27.6688 0.990234 20.2 4.91125E-11 120.79 0.998292 27.6688 6.87413E-12 135.07 1 T LGHWVTTPPDIPG CK2;ERK/MAPK;FHA1 Rad53p;Proline-directed 0.0034 6.87413E-12 135.07 _SFSTGSDLGHWVTpTPPDIPGSR_ SFSTGSDLGHWVT(0.002)T(0.998)PPDIPGSR S(-119.15)FS(-113.15)T(-100.79)GS(-86.05)DLGHWVT(-27.67)T(27.67)PPDIPGS(-61.93)R 14 3 798.69691 0.052841 1228300 328790 0 0 899530 0 0 0 3294 1389 125 125 3386 3827 31897 19738 Mix4_InSol_Tio2_Reinj_1 4073 31901 19742 Mix4_TiO2_Reinj_1_4 3675 Q96CB8 Q96CB8 Q96CB8 >sp|Q96CB8|INT12_HUMAN Integrator complex subunit 12 OS=Homo sapiens GN=INTS12 PE=1 SV=1 0.24149 0 0.000517978 -31.1664 8.18407E-17 172.83 0 0 0.00127366 -27.2433 1.50773E-33 216.22 0.00126963 -28.7029 7.35489E-05 98.218 0.24149 0 0.0665819 54.118 1 T RLEKPETQSSPIT CHK1;FHA KAPP;PKD 0.020748 1.50773E-33 216.22 _LEKPEpTQSSPITVQSSK_ LEKPET(0.241)QS(0.241)S(0.129)PIT(0.129)VQS(0.129)S(0.129)K LEKPET(0)QS(0)S(-2.71)PIT(-2.71)VQS(-2.71)S(-2.71)K 6 2 969.97463 0.17883 0 0 0 0 0 0 0 0 3295 1391 470 470 1181 1326 11089 6793 Mix4_InSol_Tio2_Reinj_1 4762 11088 6792 Mix4_InSol_TiO2_1 4817 Q96D46 Q96D46 Q96D46 >sp|Q96D46|NMD3_HUMAN 60S ribosomal export protein NMD3 OS=Homo sapiens GN=NMD3 PE=1 SV=1 0.89543 9.3856 0.00480151 -23.1653 0.00701361 75.265 0.89543 9.3856 0.557662 28 1 T IPVESDTDDEGAP CK2 0.117 0.00701361 75.265 _DSAIPVESDpTDDEGAPR_ DS(0.001)AIPVES(0.103)DT(0.895)DDEGAPR DS(-28)AIPVES(-9.39)DT(9.39)DDEGAPR 10 2 927.37547 0.098654 28185 0.1368 0 0 0 0 0 0 28185 3296 1407 618 618 1837 2074 16818 10124 Mix4_TiO2_1_5 6188 16818 10124 Mix4_TiO2_1_5 6188 Q96GX5;Q96GX5-3;Q96GX5-2 Q96GX5 Q96GX5 >sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1;>sp|Q96GX5-3|MASTL_HUMAN Isoform 3 of Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL;>sp|Q96GX5-2|MA 0.499941 0 0.499941 0 1.29211E-25 161.06 0 0 1 T PDCQEKTSPKGVE 1.29211E-25 161.06 _ESSFEESNIEDPLIVTPDCQEKpTSPK_ ESSFEESNIEDPLIVTPDCQEKT(0.5)S(0.5)PK ES(-159.82)S(-159.82)FEES(-160.03)NIEDPLIVT(-36.3)PDCQEKT(0)S(0)PK 23 3 1020.4528 -0.29751 293770 293770 0 0 0 0 0 0 3297 1430 440 440 5047 5741 48802 29830 Mix4_TiO2_1_3 3154 48803 29831 Mix4_TiO2_Reinj_1_3 3698 Q96L34;Q96L34-2 Q96L34 Q96L34 >sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1;>sp|Q96L34-2|MARK4_HUMAN Isoform MARKL1S of MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 0.322238 0 0.322238 0 0.0224997 62.374 0.318241 0 0.0189005 65.529 0 0 1 T HPKRSPTSTGEAE CAMK2;PKA;PKA/AKT 0.00111111 0.0189005 65.529 _RpSPTSTGEAELKEER_ RS(0.322)PT(0.322)S(0.322)T(0.033)GEAELKEER RS(0)PT(0)S(0)T(-9.86)GEAELKEER 4 3 590.60703 0.29562 0 0 0 0 0 0 0 0 3298 1430 442 442 5047 5741 48803 29831 Mix4_TiO2_Reinj_1_3 3698 48803 29831 Mix4_TiO2_Reinj_1_3 3698 Q96L34;Q96L34-2 Q96L34 Q96L34 >sp|Q96L34|MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1;>sp|Q96L34-2|MARK4_HUMAN Isoform MARKL1S of MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 0.318241 0 0.033287 -9.85902 0.0224997 62.374 0.318241 0 0.0189005 65.529 0 0 1 T KRSPTSTGEAELK FHA KAPP 0.155 0.0189005 65.529 _RSPpTSTGEAELKEER_ RS(0.045)PT(0.318)S(0.318)T(0.318)GEAELKEER RS(-8.47)PT(0)S(0)T(0)GEAELKEER 6 3 590.60703 -0.036419 0 0 0 0 0 0 0 0 3299 1433 140 140 6127 6993;6994 60505 36586 Mix4_TiO2_2_6 2379 60504 36585 Mix4_TiO2_1_6 2141 Q96LL9 Q96LL9 Q96LL9 >sp|Q96LL9|DJC30_HUMAN DnaJ homolog subfamily C member 30 OS=Homo sapiens GN=DNAJC30 PE=1 SV=3 0.952484 14.6786 0.10215 -9.43952 0.0233938 61.204 0.952484 14.6786 0.324417 35.542 0.815916 8.54619 0.0609232 54.941 0 0 0 0 1 T DPGSPRTPPPTSR CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0233938 61.204 _TPAPDPGSPRpTPPPTSR_ TPAPDPGS(0.032)PRT(0.952)PPPT(0.007)S(0.007)R T(-35.54)PAPDPGS(-14.68)PRT(14.68)PPPT(-21.09)S(-21.09)R 11 3 604.28764 0.15343 71101 0 35222 0 35879 0 0 0 3300 1443 572 572 2385 2699;2701 22185 13837 Mix4_TiO2_Reinj_1_3 6020 22165 13832 Mix4_TiO2_Reinj_1_3 6782 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.933932 12.7556 0.779452 5.57268 8.68195E-07 108.14 0.933932 12.7556 6.7099E-26 161.27 0.750445 5.11103 0.00178906 85.092 0.720765 5.28127 9.36249E-07 107.35 1 T VANANSTPPPYER Polo box;Proline-directed 0.00405 6.7099E-26 161.27 _GQPGNAYDGAGQPSAAYLSM(ox)SQGAVANANSpTPPPYER_ GQPGNAYDGAGQPSAAYLSMS(0.001)QGAVANANS(0.05)T(0.934)PPPY(0.015)ER GQPGNAY(-101.11)DGAGQPS(-68.43)AAY(-61.27)LS(-42.75)MS(-28.21)QGAVANANS(-12.76)T(12.76)PPPY(-17.92)ER 31 3 1264.2195 -1.4367 5860800 1.3407 619700 0 0 3174800 0 1180600 885690 3301 1443 629 629 3718;5045;5590 4192;5738;6371 48782 29817 Mix4_InSol_TiO2_1 3557 35086 21733 Mix4_InSol_Tio2_Reinj_1 5106 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.966304 15.2629 0 0 0 0 0 0 0.966304 15.2629 0.00281086 73.187 0.601149 2.06951 0.00736776 75.777 1 T SFRRSPTKSSLDY CAMK2;FHA KAPP;PKA/AKT 0.00111111 0.00736776 75.777 _RSPpTKSSLDYR_ RS(0.029)PT(0.966)KS(0.002)S(0.002)LDY(0.002)R RS(-15.26)PT(15.26)KS(-27.69)S(-27.69)LDY(-27.69)R 4 3 463.88892 -0.21815 3491100 0 0 0 0 0 1459600 2031500 3302 1443 206 206 4682 5313 44423 27233 Mix4_TiO2_Reinj_1_6 5580 44416 27202 Mix4_TiO2_2_3 4467 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 1 43.1258 1 40.6292 0.0332717 52.351 1 12.3041 0.00279017 74.194 1 43.1258 0.0332717 52.351 1 40.6292 0.0737925 40.629 1 28.2516 0.188245 32.465 1 T GQARQPTPPFFGR CAMK2;Proline-directed 0.042 0.00279017 74.194 _QPpTPPFFGR_ QPT(1)PPFFGR QPT(43.13)PPFFGR 3 2 563.7577 0.032888 14373000 3274600 366810 0 8129100 0 1530500 1071700 3303 1446 471 471 5474 6230 53385 32622 Mix4_TiO2_Reinj_1_3 6894 53387 32624 Mix4_TiO2_Reinj_1_5 6813 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.318357 0 0.00629903 -19.5597 2.61896E-09 130.23 0.00142305 -25.3792 0.561748 27.868 0.318357 0 1.65313E-09 132.86 0 0 0.295819 0 4.46122E-09 125.21 0.257002 0 7.2865E-06 104.29 1 T RSLSSPTVTLSAP CK1;FHA2 Rad53p 0.081 1.65313E-09 132.86 _SLpSSPTVTLSAPLEGAK_ S(0.004)LS(0.318)S(0.318)PT(0.318)VT(0.041)LSAPLEGAK S(-19.36)LS(0)S(0)PT(0)VT(-8.88)LS(-55.72)APLEGAK 6 3 579.96053 -0.44876 0 0 0 0 0 0 0 0 3304 1447 689 689 5692;5693 6483;6484;6485 55747 34162 Mix4_TiO2_1_1 2767 55748 34164 Mix4_TiO2_1_5 3106 Q96PY6-3;Q96PY6;Q96PY6-2;Q96PY6-4 Q96PY6-3 Q96PY6-3 >sp|Q96PY6-3|NEK1_HUMAN Isoform 3 of Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1;>sp|Q96PY6|NEK1_HUMAN Serine/threonine-protein kinase Nek1 OS=Homo sapiens GN=NEK1 PE=1 SV=2;>sp|Q96PY6-2|NEK1_HUMAN Isoform 2 of Serine/threonine-protein kin 0.676751 8.3979 0.676751 8.3979 7.87298E-16 149.26 0 0 0.66598 3.0202 0.00479451 75.894 0 0 0.649887 5.10261 1.38329 22.703 1 T PLGQHETGGSPSK FHA KAPP 0.155 7.87298E-16 149.26 _SSDVSPPLGQHEpTGGSPSK_ S(0.043)S(0.043)DVS(0.043)PPLGQHET(0.677)GGS(0.098)PS(0.098)K S(-12.02)S(-12.02)DVS(-12.02)PPLGQHET(8.4)GGS(-8.4)PS(-8.4)K 13 3 649.62123 -0.8738 552390 24672 0 0 474180 0 0 53534 3305 1448 3565 3565 4114 4684;4685 38980 23912 Mix4_InSol_Tio2_Reinj_1 4635 38982 23917 Mix4_TiO2_Reinj_1_1 3951 Q96Q15;Q96Q15-2;Q96Q15-3;Q96Q15-4 Q96Q15 Q96Q15 >sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1 PE=1 SV=2;>sp|Q96Q15-2|SMG1_HUMAN Isoform 2 of Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1;>sp|Q96Q15-3|SMG1_HUMAN Isoform 3 of Serine/threonine-protein kin 0.668227 2.76753 0.0373239 -14.1149 4.77683E-06 104.69 0.0128982 -17.1299 0.781467 22.582 0.261268 -4.51044 1.61073E-06 113.57 0.0150641 -15.8364 0.141403 44.057 0.256305 -0.950341 8.32694E-10 119.42 0.668227 2.76753 0.0168437 66.086 2 T IQKNLATSADTPP CK2;FHA1 Rad53p 0.059 1.61073E-06 113.57 _NLApTSADpTPPSTVPGTGK_ NLAT(0.668)S(0.414)ADT(0.865)PPS(0.052)T(0.001)VPGTGK NLAT(2.77)S(-2.77)ADT(7.56)PPS(-13.91)T(-30.88)VPGT(-64.55)GK 4 2 937.40265 0.27113 81826 0 0 0 0 0 0 81826 3306 1448 3569 3569 4114 4684;4685 38994 23922 Mix4_InSol_Tio2_Reinj_1 4693 39001 23930 Mix4_TiO2_Reinj_1_1 3931 Q96Q15;Q96Q15-2;Q96Q15-3;Q96Q15-4 Q96Q15 Q96Q15 >sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1 PE=1 SV=2;>sp|Q96Q15-2|SMG1_HUMAN Isoform 2 of Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1;>sp|Q96Q15-3|SMG1_HUMAN Isoform 3 of Serine/threonine-protein kin 0.883189 11.7529 0.880901 11.5676 4.77683E-06 104.69 0.666073 8.01811 0.781467 22.582 0.773567 8.0468 1.0712E-10 135.06 0.067073 -9.35036 0.141403 44.057 0.999456 34.1736 4.82389E-06 104.56 0.883189 11.7529 9.04747E-07 115.57 1 T LATSADTPPSTVP CK1;FHA KAPP;Proline-directed 0.05 1.0712E-10 135.06 _NLATSADpTPPSTVPGTGK_ NLAT(0.008)S(0.059)ADT(0.883)PPS(0.039)T(0.01)VPGTGK NLAT(-20.26)S(-11.75)ADT(11.75)PPS(-13.5)T(-19.46)VPGT(-45.65)GK 8 2 897.41949 0.30166 989770 197450 10758 0 644810 0 0 136750 3307 1455 201 201 2666 3033;3034;3035 24891 15393 Mix4_TiO2_1_5 7412 24898 15404 Mix4_TiO2_Reinj_1_6 7088 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.496035 0 0.496035 0 7.55206E-08 108.48 0 0 0.483089 2.99701 5.17015E-08 111.54 0 0 2 T WDKHSVTAATPPP 5.17015E-08 111.54 _HpSVTAATPPPpSPTSGESGDLLSNLLQSPSSAK_ HS(0.496)VT(0.496)AAT(0.024)PPPS(0.788)PT(0.195)S(0.001)GESGDLLSNLLQSPSSAK HS(0)VT(0)AAT(-17.25)PPPS(6.08)PT(-6.08)S(-30.22)GES(-35.88)GDLLS(-50.07)NLLQS(-63.2)PS(-66.32)S(-66.32)AK 4 2 1647.2524 0.34758 0 0 0 0 0 0 0 0 3308 1455 204 204 2666 3033;3034;3035 24893 15396 Mix4_TiO2_Reinj_1_1 7722 24898 15404 Mix4_TiO2_Reinj_1_6 7088 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.993776 25.448 0.982917 20.0349 7.55206E-08 108.48 0 0 0.993776 25.448 5.17015E-08 111.54 0 0 2 T HSVTAATPPPSPT Proline-directed 0.05 5.17015E-08 111.54 _HSVTAApTPPPpSPTSGESGDLLSNLLQSPSSAK_ HS(0.003)VT(0.002)AAT(0.994)PPPS(0.396)PT(0.302)S(0.303)GES(0.001)GDLLSNLLQSPSSAK HS(-25.45)VT(-26)AAT(25.45)PPPS(1.17)PT(-1.17)S(-1.17)GES(-27.58)GDLLS(-46.2)NLLQS(-81.37)PS(-84.82)S(-81.1)AK 7 3 1098.504 0.063367 22850000 5520100 0 0 17330000 0 0 0 3309 1455 210 210 2666 3033;3034;3035 24910 15409 Mix4_TiO2_1_6 6058 24913 15412 Mix4_TiO2_Reinj_1_5 7920 Q96QU8 Q96QU8 Q96QU8 >sp|Q96QU8|XPO6_HUMAN Exportin-6 OS=Homo sapiens GN=XPO6 PE=1 SV=1 0.441854 0 0.441854 0 0.000279246 85.455 0 0 0.396949 0 0.000149888 91.652 0 0 1 T TPPPSPTSGESGD CK2 0.117 0.000149888 91.652 _HSVTAATPPPpSPTSGESGDLLSNLLQSPSSAK_ HS(0.002)VT(0.001)AAT(0.008)PPPS(0.442)PT(0.442)S(0.103)GES(0.002)GDLLSNLLQSPSSAK HS(-23.09)VT(-27.76)AAT(-17.67)PPPS(0)PT(0)S(-6.31)GES(-22.78)GDLLS(-36.6)NLLQS(-63.08)PS(-66.6)S(-62.78)AK 13 3 1071.8486 -0.10454 0 0 0 0 0 0 0 0 3310 1463 7 7 591 679 5622 3335 Mix4_InSol_Tio2_Reinj_1 6397 5624 3338 Mix4_TiO2_1_2 4400 Q96S44 Q96S44 Q96S44 >sp|Q96S44|PRPK_HUMAN TP53-regulating kinase OS=Homo sapiens GN=TP53RK PE=1 SV=2 0.751266 4.80059 0.5 0 3.51035E-39 210.01 0.5 0 1.02759E-38 201.39 0 0 0.751266 4.80059 2.58998E-11 131.04 1 T MAAARATTPADGE FHA KAPP;PKA 0.042 3.51035E-39 210.01 _ApTTPADGEEPAPEAEALAAAR_ AT(0.751)T(0.249)PADGEEPAPEAEALAAAR AT(4.8)T(-4.8)PADGEEPAPEAEALAAAR 2 3 706.65108 1.0737 2455300 19.529 720960 0 0 1678900 0 0 55441 3311 1463 8 8 591 679 5631 3346 Mix4_TiO2_Reinj_1_6 5136 5624 3338 Mix4_TiO2_1_2 4400 Q96S44 Q96S44 Q96S44 >sp|Q96S44|PRPK_HUMAN TP53-regulating kinase OS=Homo sapiens GN=TP53RK PE=1 SV=2 0.896866 9.39324 0.5 0 3.51035E-39 210.01 0.896866 9.39324 1.02759E-38 201.39 0 0 0.844417 7.34594 2.58998E-11 131.04 1 T AAARATTPADGEE CAMK2;CK2;FHA1 Rad53p;Proline-directed 0.042 3.51035E-39 210.01 _ATpTPADGEEPAPEAEALAAAR_ AT(0.103)T(0.897)PADGEEPAPEAEALAAAR AT(-9.39)T(9.39)PADGEEPAPEAEALAAAR 3 3 706.65108 0.37504 2651700 21.091 720960 0 0 1854300 0 0 76470 3312 1478 385 385 2221 2514 20403 12518 Mix4_TiO2_1_5 5091 20403 12518 Mix4_TiO2_1_5 5091 Q99459 Q99459 Q99459 >sp|Q99459|CDC5L_HUMAN Cell division cycle 5-like protein OS=Homo sapiens GN=CDC5L PE=1 SV=2 0.993661 22.8218 0.993661 22.8218 0.0183517 62.384 2 T LKGGLNTPLHESD Proline-directed 0.05 0.0183517 62.384 _GGLNpTPLHESDFSGVpTPQR_ GGLNT(0.994)PLHES(0.005)DFS(0.001)GVT(1)PQR GGLNT(22.82)PLHES(-22.82)DFS(-29.36)GVT(41.92)PQR 5 2 1086.4616 0.38366 25934 25934 0 0 0 0 0 0 3313 1478 396 396 2221 2514 20403 12518 Mix4_TiO2_1_5 5091 20403 12518 Mix4_TiO2_1_5 5091 Q99459 Q99459 Q99459 >sp|Q99459|CDC5L_HUMAN Cell division cycle 5-like protein OS=Homo sapiens GN=CDC5L PE=1 SV=2 0.999933 41.9238 0.999933 41.9238 0.0183517 62.384 2 T SDFSGVTPQRQVV CDK1;CDK2;CK1;Proline-directed 0.0057 0.0183517 62.384 _GGLNpTPLHESDFSGVpTPQR_ GGLNT(0.994)PLHES(0.005)DFS(0.001)GVT(1)PQR GGLNT(22.82)PLHES(-22.82)DFS(-29.36)GVT(41.92)PQR 16 2 1086.4616 0.38366 25934 25934 0 0 0 0 0 0 3314 1485 94 94 3074 3494 29279 18272 Mix4_TiO2_Reinj_1_2 1330 29279 18272 Mix4_TiO2_Reinj_1_2 1330 Q99623 Q99623 Q99623 >sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=PHB2 PE=1 SV=2 0.99035 20.2553 0.782285 7.13834 0.149244 35.247 0.99035 20.2553 0.00240509 75.156 0 0 0 0 1 T RKISSPTGSKDLQ CK1 0.081 0.00240509 75.156 _KISSPpTGSK_ KISS(0.009)PT(0.99)GSK KIS(-38.14)S(-20.26)PT(20.26)GS(-37.94)K 6 2 492.74171 -0.11519 688390 2.5883 36630 0 0 651760 0 0 0 3315 1486 495 495 4146 4721 39524 24394 Mix4_TiO2_Reinj_1_4 9224 39524 24394 Mix4_TiO2_Reinj_1_4 9224 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 1 72.7721 0 0 1 72.7721 1.08081E-13 188.66 1 T LSLFEDTLDPT__ PLK1 0.033462 1.08081E-13 188.66 _NLLSLFEDpTLDPT_ NLLSLFEDT(1)LDPT NLLS(-161.32)LFEDT(72.77)LDPT(-72.77) 9 2 779.35784 0.18706 79497 0 0 0 79497 0 0 0 3316 1486 455 455 6281 7176 62784 38204 Mix4_TiO2_1_4 1188 62784 38204 Mix4_TiO2_1_4 1188 Q99640 Q99640 Q99640 >sp|Q99640|PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase OS=Homo sapiens GN=PKMYT1 PE=1 SV=1 0.99583 23.8331 0.99583 23.8331 0.00171487 91.715 0.528442 0.985705 0.00622438 65.609 0.497129 0 0.0236317 55.403 0.919077 10.5896 0.0696249 40.926 0.930731 11.6245 0.031459 52.925 1 T TVGSTSTPRSRCT CDK1;CK1;FHA KAPP;Polo box;Proline-directed 0.00405 0.00171487 91.715 _TVGSTSpTPR_ TVGSTS(0.004)T(0.996)PR T(-91.72)VGS(-61.65)T(-43.03)S(-23.83)T(23.83)PR 7 2 493.22115 0.39168 3074600 1037700 993950 0 0 0 194610 848270 3317 1489 741 741 629 724 5983 3509 Mix4_TiO2_Reinj_1_5 1953 5982 3508 Mix4_TiO2_Reinj_1_3 1878 Q99700;Q99700-4;Q99700-2 Q99700 Q99700 >sp|Q99700|ATX2_HUMAN Ataxin-2 OS=Homo sapiens GN=ATXN2 PE=1 SV=2;>sp|Q99700-4|ATX2_HUMAN Isoform 4 of Ataxin-2 OS=Homo sapiens GN=ATXN2;>sp|Q99700-2|ATX2_HUMAN Isoform 2 of Ataxin-2 OS=Homo sapiens GN=ATXN2 0.9899 20.4838 0.263732 -1.44842 0.578193 13.669 0.940889 15.029 0.222527 30.02 0.9899 20.4838 0.0389634 50.549 0 0 0 0 1 T ASNRAVTPSSEAK CAMK2;FHA KAPP;Proline-directed 0.042 0.0389634 50.549 _AVpTPSSEAK_ AVT(0.99)PS(0.009)S(0.001)EAK AVT(20.48)PS(-20.48)S(-29.01)EAK 3 2 485.21807 1.1039 388110 0 31720 0 356390 0 0 0 3318 1499 664 664 6064;6065 6918;6919 59860 36309 Mix4_TiO2_Reinj_1_3 8267 59854 36305 Mix4_TiO2_1_5 2862 Q9BPX3 Q9BPX3 Q9BPX3 >sp|Q9BPX3|CND3_HUMAN Condensin complex subunit 3 OS=Homo sapiens GN=NCAPG PE=1 SV=1 0.55109 5.79695 0.47447 0 2.11788E-11 136.91 0.289922 0 2.15117 4.4093 0.55109 5.79695 3.52563E-12 129.21 0 0 0 0 1 T KTKKIKTLHCEGT 2.11788E-11 136.91 _pTLHCEGTEINSDDEQESKEVEETATAK_ T(0.551)LHCEGT(0.138)EINS(0.145)DDEQES(0.055)KEVEET(0.055)AT(0.055)AK T(5.8)LHCEGT(-6.01)EINS(-5.8)DDEQES(-9.99)KEVEET(-9.99)AT(-9.99)AK 1 3 1044.1063 -0.1006 1760900 0 0 0 1760900 0 0 0 3319 1499 670 670 6064;6065 6918;6919 59858 36307 Mix4_TiO2_1_6 6190 59854 36305 Mix4_TiO2_1_5 2862 Q9BPX3 Q9BPX3 Q9BPX3 >sp|Q9BPX3|CND3_HUMAN Condensin complex subunit 3 OS=Homo sapiens GN=NCAPG PE=1 SV=1 0.47447 0 0.47447 0 2.11788E-11 136.91 0.289922 0 2.15117 4.4093 0.138251 -6.00554 3.52563E-12 129.21 0 0 0 0 1 T TLHCEGTEINSDD 2.11788E-11 136.91 _pTLHCEGTEINSDDEQESKEVEETATAK_ T(0.474)LHCEGT(0.474)EINS(0.014)DDEQES(0.012)KEVEET(0.012)AT(0.012)AK T(0)LHCEGT(0)EINS(-15.17)DDEQES(-15.9)KEVEET(-15.9)AT(-15.9)AK 7 3 1044.1063 -0.53563 0 0 0 0 0 0 0 0 3320 1502 5 5 3012 3426 28775 17918 Mix4_TiO2_Reinj_1_4 5036 28774 17917 Mix4_TiO2_Reinj_1_4 5012 Q9BQA1 Q9BQA1 Q9BQA1 >sp|Q9BQA1|MEP50_HUMAN Methylosome protein 50 OS=Homo sapiens GN=WDR77 PE=1 SV=1 1 8.84243 1 25.0299 0.347351 25.03 0 0 1 8.84243 0.0193628 62.136 1 T __MRKETPPPLVP CAMK2;PKA;Proline-directed 0.004788 0.0193628 62.136 _KEpTPPPLVPPAAR_ KET(1)PPPLVPPAAR KET(8.84)PPPLVPPAAR 3 3 484.9252 -0.25799 645860 129160 0 0 516690 0 0 0 3321 1504 1239 1239 5544;5545 6318;6319 54245 33218 Mix4_TiO2_Reinj_1_5 2694 54245 33218 Mix4_TiO2_Reinj_1_5 2694 Q9BQG0-2;Q9BQG0 Q9BQG0-2 Q9BQG0-2 >sp|Q9BQG0-2|MBB1A_HUMAN Isoform 2 of Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A;>sp|Q9BQG0|MBB1A_HUMAN Myb-binding protein 1A OS=Homo sapiens GN=MYBBP1A PE=1 SV=2 0.888644 9.20939 0.0123262 -18.6932 0.00161498 86.268 0.888644 9.20939 0.000761867 92.946 0.473879 0 0.643693 28.865 0.00823155 -19.3033 0.938506 21.176 1 T PAPGAPTRSPSTP 0.000761867 92.946 _SPAPGAPpTRSPSTPAK_ SPAPGAPT(0.889)RS(0.107)PS(0.005)TPAK S(-78.22)PAPGAPT(9.21)RS(-9.21)PS(-22.73)T(-52.62)PAK 8 2 801.38779 -0.021368 298770 0 0 0 298770 0 0 0 3322 1517 107 107 6129 6996 60528 36591 Mix4_TiO2_Reinj_1_4 7545 60528 36591 Mix4_TiO2_Reinj_1_4 7545 Q9BTV7 Q9BTV7 Q9BTV7 >sp|Q9BTV7|CABL2_HUMAN CDK5 and ABL1 enzyme substrate 2 OS=Homo sapiens GN=CABLES2 PE=1 SV=3 0.497437 0 0 0 0.497437 0 0.000919314 79.243 1 T QGLLSPTQVPTGL NEK6 0.076 0.000919314 79.243 _TPAPQGLLpSPTQVPTGLGLDGQR_ T(0.005)PAPQGLLS(0.497)PT(0.497)QVPTGLGLDGQR T(-19.87)PAPQGLLS(0)PT(0)QVPT(-52.14)GLGLDGQR 11 3 795.07209 0.19655 0 0 0 0 0 0 0 0 3323 1519 414 414 3119 3542;3543 29661 18462 Mix4_InSol_TiO2_1 5025 29661 18462 Mix4_InSol_TiO2_1 5025 Q9BTX1;Q9BTX1-2;Q9BTX1-4 Q9BTX1 Q9BTX1 >sp|Q9BTX1|NDC1_HUMAN Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48 PE=1 SV=2;>sp|Q9BTX1-2|NDC1_HUMAN Isoform 2 of Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48;>sp|Q9BTX1-4|NDC1_HUMAN Isoform 4 of Nucleoporin NDC1 OS=Homo sapiens GN=TMEM48 1 70.167 0.990631 23.2525 0.000183516 102.35 0 0 0.999998 57.0728 1.41692E-07 136 1 70.167 1.14817E-08 138.13 0.999444 32.5473 0.000143565 105.81 1 T EETAFQTPKSSQM CDK1;FHA KAPP;Proline-directed 0.0057 1.14817E-08 138.13 _KLNSPEETAFQpTPK_ KLNSPEETAFQT(1)PK KLNS(-134.49)PEET(-70.17)AFQT(70.17)PK 12 2 835.39528 0.39212 569870 22414 0 0 346760 0 71370 129330 3324 1530 481 481 6087 6942;6943 60147 36438 Mix4_TiO2_Reinj_1_3 7067 60147 36438 Mix4_TiO2_Reinj_1_3 7067 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.850934 7.77198 0.822303 6.86164 0.000571471 80.516 0.850934 7.77198 0.000203383 92.329 0.769539 6.86749 0.026846 59.447 0.362656 -0.487629 0.51042 36.01 1 T NQYRTRTLSITSS CAMK2;FHA2 Rad53p;PKA/AKT 0.00111111 0.000203383 92.329 _pTLSITSSGSAVSCSTIPPELVK_ T(0.851)LS(0.142)IT(0.003)S(0.003)S(0.001)GS(0.001)AVSCSTIPPELVK T(7.77)LS(-7.77)IT(-24.65)S(-24.65)S(-31.91)GS(-31.91)AVS(-68.43)CS(-81.68)T(-87.57)IPPELVK 1 3 772.04644 -0.2466 1856800 888150 0 0 625960 0 342740 0 3325 1530 485 485 6087 6942;6943 60143 36430 Mix4_InSol_Tio2_Reinj_1 7473 60147 36438 Mix4_TiO2_Reinj_1_3 7067 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.222246 0 0.113277 -7.21509 0.000571471 80.516 0.129262 -7.69074 0.000203383 92.329 0.0906024 -6.98839 0.026846 59.447 0.222246 0 0.51042 36.01 1 T TRTLSITSSGSAV NEK6 0.076 0.000203383 92.329 _TLpSITSSGSAVSCSTIPPELVK_ T(0.2)LS(0.222)IT(0.222)S(0.222)S(0.038)GS(0.038)AVS(0.045)CS(0.01)T(0.002)IPPELVK T(-0.45)LS(0)IT(0)S(0)S(-7.71)GS(-7.71)AVS(-6.89)CS(-13.57)T(-19.56)IPPELVK 5 3 772.04644 -0.28267 0 0 0 0 0 0 0 0 3326 1537 114 114 4311;4968 4904;5649 47932 29309 Mix4_TiO2_1_4 3670 47931 29307 Mix4_TiO2_1_4 3639 Q9BX95 Q9BX95 Q9BX95 >sp|Q9BX95|SGPP1_HUMAN Sphingosine-1-phosphate phosphatase 1 OS=Homo sapiens GN=SGPP1 PE=1 SV=2 0.9906 20.2278 0.9906 20.2278 2.0251E-06 149.63 0.252328 -4.71746 0.0592799 49.823 0.874409 8.42758 0.00012709 115.47 0.894844 9.29913 0.00430268 81.524 0.900832 9.5827 0.0015514 94.405 1 T LRRNSLTGEEGQL CK2 0.117 2.0251E-06 149.63 _RNSLpTGEEGQLAR_ RNS(0.009)LT(0.991)GEEGQLAR RNS(-20.23)LT(20.23)GEEGQLAR 5 3 504.2385 0.037177 4293400 207180 0 0 3322500 0 492380 271330 3327 1541 544 544 6178 7055 61212 37088 Mix4_TiO2_1_5 7352 61212 37088 Mix4_TiO2_1_5 7352 Q9BXP5;Q9BXP5-3;Q9BXP5-2;Q9BXP5-4;Q9BXP5-5 Q9BXP5 Q9BXP5 >sp|Q9BXP5|SRRT_HUMAN Serrate RNA effector molecule homolog OS=Homo sapiens GN=SRRT PE=1 SV=1;>sp|Q9BXP5-3|SRRT_HUMAN Isoform 3 of Serrate RNA effector molecule homolog OS=Homo sapiens GN=SRRT;>sp|Q9BXP5-2|SRRT_HUMAN Isoform B of Serrate RNA effector molec 0.996715 26.813 0.996715 26.813 0.0103825 70.785 0 0 1 T WASEPGTPPLPTS ERK/MAPK;FHA2 Rad53p;Proline-directed 0.0025 0.0103825 70.785 _TQLWASEPGpTPPLPTSLPSQNPILK_ TQLWAS(0.002)EPGT(0.997)PPLPTS(0.001)LPSQNPILK T(-40.27)QLWAS(-26.81)EPGT(26.81)PPLPT(-37.16)S(-31.51)LPS(-36.55)QNPILK 10 3 918.13676 -0.25777 72236 72236 0 0 0 0 0 0 3328 1542 757 757 4456 5067 42323 26041 Mix4_TiO2_2_2 3320 42324 26042 Mix4_TiO2_Reinj_1_1 3756 Q9BXS9;Q9BXS9-2 Q9BXS9 Q9BXS9 >sp|Q9BXS9|S26A6_HUMAN Solute carrier family 26 member 6 OS=Homo sapiens GN=SLC26A6 PE=1 SV=1;>sp|Q9BXS9-2|S26A6_HUMAN Isoform 2 of Solute carrier family 26 member 6 OS=Homo sapiens GN=SLC26A6 0.85464 10.2446 0.00113832 -29.3857 0.0446969 50.208 0.85464 10.2446 0.425362 15.834 0.00057027 -32.4323 0.0275029 55.307 0 0 0 0 0 0 1 T DSPVSVTRL____ 0.0275029 55.307 _PVPDSPVSVpTR_ PVPDS(0.065)PVS(0.081)VT(0.855)R PVPDS(-11.22)PVS(-10.24)VT(10.24)R 10 2 617.29739 -0.32798 25524 0 25524 0 0 0 0 0 3329 1551 440 440 5875 6700 57931 35199 Mix4_InSol_TiO2_1 6767 57933 35201 Mix4_TiO2_1_4 5631 Q9BYT3 Q9BYT3 Q9BYT3 >sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo sapiens GN=STK33 PE=1 SV=1 0.328797 0 0.270827 0 0.000115385 91.141 0 0 0.328797 0 0.0306766 61.791 0 0 1 T VPDANYTSDEEEE CK2 0.117 0.000115385 91.141 _SYQPWGNVPDANpYTSDEEEEKQSTAYEK_ SYQPWGNVPDANY(0.329)T(0.329)S(0.329)DEEEEKQS(0.009)T(0.002)AY(0.002)EK S(-61.39)Y(-61.39)QPWGNVPDANY(0)T(0)S(0)DEEEEKQS(-15.56)T(-21.91)AY(-21.47)EK 14 3 1115.7963 -0.069977 0 0 0 0 0 0 0 0 3330 1559 211 211 3466 3912 32650 20242 Mix4_TiO2_1_5 5260 32651 20243 Mix4_TiO2_Reinj_1_3 6131 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.325542 0 0.325542 0 0.00219328 81.742 0.0329506 -14.6198 0.00109967 90.326 0.0121575 -18.7801 0.801995 18.78 0.052082 -12.2987 0.0977606 49.107 1 T HSVRLGTSESLPC CAMK2;FHA KAPP 0.042 0.00109967 90.326 _LGpTSESLPCTAEELSR_ LGT(0.326)S(0.326)ES(0.279)LPCT(0.035)AEELS(0.035)R LGT(0)S(0)ES(-0.68)LPCT(-9.66)AEELS(-9.66)R 3 2 915.40298 1.2467 0 0 0 0 0 0 0 0 3331 1559 199 199 3747;4960;5027 4227;5640;5641;5718 47771 29231 Mix4_TiO2_1_5 3324 47764 29185 Mix4_TiO2_1_3 3274 Q9BZL6 Q9BZL6 Q9BZL6 >sp|Q9BZL6|KPCD2_HUMAN Serine/threonine-protein kinase D2 OS=Homo sapiens GN=PRKD2 PE=1 SV=2 0.898039 12.9284 0.898039 12.9284 3.41972E-16 191.08 0.179727 -2.50905 0.0160506 67.554 0 0 0.538272 1.62474 3.41628E-05 115.29 0.200069 -3.00653 0.0104332 72.874 0.387205 0 1.6225E-06 120.42 0.365183 -1.59998 3.24548E-09 151.45 1 T KRRLSSTSLASGH FHA KAPP;NEK6 0.076 3.41972E-16 191.08 _RLSSpTSLASGHSVR_ RLS(0.046)S(0.046)T(0.898)S(0.01)LASGHSVR RLS(-12.93)S(-12.93)T(12.93)S(-19.34)LAS(-75.16)GHS(-125.56)VR 5 2 769.37776 -0.045377 730810 730810 0 0 0 0 0 0 3332 1561 385 385 2145 2430 19729 12067 Mix4_TiO2_Reinj_1_1 4069 19727 12065 Mix4_TiO2_1_5 3880 Q9C0B5;Q9C0B5-2 Q9C0B5 Q9C0B5 >sp|Q9C0B5|ZDHC5_HUMAN Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 PE=1 SV=2;>sp|Q9C0B5-2|ZDHC5_HUMAN Isoform 2 of Probable palmitoyltransferase ZDHHC5 OS=Homo sapiens GN=ZDHHC5 0.499996 0 0.0101363 -19.8968 1.65525E-05 114.82 0 0 0.499996 0 2.61622E-05 112.83 0 0 0 0 0 0 1 T DSLKEPTSIAESS FHA KAPP 0.155 1.65525E-05 114.82 _GDpSLKEPTSIAESSR_ GDS(0.5)LKEPT(0.5)SIAESSR GDS(0)LKEPT(0)S(-48.32)IAES(-100.6)S(-100.6)R 8 3 552.92073 0.022243 80608 0 0 0 80608 0 0 0 3333 1563 501 501 3354 3793;3794 31604 19548 Mix4_TiO2_Reinj_1_1 7725 31604 19548 Mix4_TiO2_Reinj_1_1 7725 Q9C0C2 Q9C0C2 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=3 0.803983 8.47327 0 0 0 0 0.803983 8.47327 2.56501E-12 125.72 2 T PPPSPITEASEAA CK1;FHA KAPP 0.081 2.56501E-12 125.72 _LDpSPPPSPIpTEASEAAEAAEAGNLAVSSR_ LDS(0.809)PPPS(0.222)PIT(0.804)EAS(0.165)EAAEAAEAGNLAVSSR LDS(7.36)PPPS(-7.36)PIT(8.47)EAS(-8.47)EAAEAAEAGNLAVS(-125.72)S(-125.72)R 10 3 999.77572 0.33183 659030 0 0 0 659030 0 0 0 3334 1565 526 526 2641 3004 24633 15271 Mix4_TiO2_Reinj_1_6 3680 24632 15269 Mix4_TiO2_Reinj_1_5 4309 Q9C0E2 Q9C0E2 Q9C0E2 >sp|Q9C0E2|XPO4_HUMAN Exportin-4 OS=Homo sapiens GN=XPO4 PE=1 SV=2 0.280495 0 0.0922222 -8.94503 9.48475E-13 145.93 0 0 0.280495 0 2.8115E-35 233.46 0.099822 -8.5292 7.57813E-06 103.74 0.00174586 -25.0931 2.34579E-06 113.65 1 T ASPGSSTVDNKML 2.8115E-35 233.46 _HQQQLLASPGpSSTVDNK_ HQQQLLAS(0.159)PGS(0.28)S(0.28)T(0.28)VDNK HQQQLLAS(-2.48)PGS(0)S(0)T(0)VDNK 13 3 630.62995 -1.0468 0 0 0 0 0 0 0 0 3335 1566 179 179 4164;4165 4741;4742;4743 39692 24493 Mix4_InSol_Tio2_Reinj_1 5569 39702 24509 Mix4_TiO2_Reinj_1_4 5099 Q9C0E8;Q9C0E8-2;Q9C0E8-3 Q9C0E8 Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens GN=LNP PE=1 SV=2;>sp|Q9C0E8-2|LNP_HUMAN Isoform 2 of Protein lunapark OS=Homo sapiens GN=LNP;>sp|Q9C0E8-3|LNP_HUMAN Isoform 3 of Protein lunapark OS=Homo sapiens GN=LNP 0.993784 22.4045 0.969304 15.1784 1.09501E-17 139.75 0.0508478 -12.6922 0.00025167 88.201 0.496704 0 6.88165E-18 146.06 0.389902 0 4.18529E-07 104.83 0.993784 22.4045 1.44624E-07 113.52 1 T QRNLSPTPASPNQ FHA KAPP;NEK6;Proline-directed 0.05 6.88165E-18 146.06 _NLSPpTPASPNQGPPPQVPVSPGPPK_ NLS(0.006)PT(0.994)PAS(0.001)PNQGPPPQVPVSPGPPK NLS(-22.4)PT(22.4)PAS(-32.96)PNQGPPPQVPVS(-113.52)PGPPK 5 3 847.42301 0.33318 849180 381790 0 0 0 0 0 467390 3336 1566 213 213 6302 7202 63042 38396 Mix4_TiO2_1_4 5294 63042 38396 Mix4_TiO2_1_4 5294 Q9C0E8;Q9C0E8-2;Q9C0E8-3 Q9C0E8 Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens GN=LNP PE=1 SV=2;>sp|Q9C0E8-2|LNP_HUMAN Isoform 2 of Protein lunapark OS=Homo sapiens GN=LNP;>sp|Q9C0E8-3|LNP_HUMAN Isoform 3 of Protein lunapark OS=Homo sapiens GN=LNP 0.999139 30.6469 0.999139 30.6469 0.000339011 108.22 0.983468 17.8588 0.0440544 53.961 0.993338 21.7349 0.00136637 95.271 0 0 1 T PPERTVTPALSSN CAMK2;FHA2 Rad53p;Proline-directed 0.042 0.000339011 108.22 _TVpTPALSSNVLPR_ T(0.001)VT(0.999)PALSSNVLPR T(-30.65)VT(30.65)PALS(-85.08)S(-76.65)NVLPR 3 2 717.87125 0.75027 283530 48078 56282 0 179170 0 0 0 3337 1573 519 519 2066 2341 18939 11554 Mix4_TiO2_Reinj_1_3 8667 18938 11552 Mix4_TiO2_1_3 8041 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.333333 0 0.333333 0 7.56397E-26 158.18 0.333333 0 8.09821E-26 156.92 1 T LELAAPTTFGSLD 7.56397E-26 158.18 _FSQTALELAAPpTTFGSLDELAPPRPLAR_ FSQTALELAAPT(0.333)T(0.333)FGS(0.333)LDELAPPRPLAR FS(-110.76)QT(-110.76)ALELAAPT(0)T(0)FGS(0)LDELAPPRPLAR 12 3 1017.1847 0.22514 0 0 0 0 0 0 0 0 3338 1573 520 520 2066 2341 18939 11554 Mix4_TiO2_Reinj_1_3 8667 18938 11552 Mix4_TiO2_1_3 8041 Q9H093 Q9H093 Q9H093 >sp|Q9H093|NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS=Homo sapiens GN=NUAK2 PE=1 SV=1 0.333333 0 0.333333 0 7.56397E-26 158.18 0.333333 0 8.09821E-26 156.92 1 T ELAAPTTFGSLDE FHA KAPP 0.155 7.56397E-26 158.18 _FSQTALELAAPpTTFGSLDELAPPRPLAR_ FSQTALELAAPT(0.333)T(0.333)FGS(0.333)LDELAPPRPLAR FS(-110.76)QT(-110.76)ALELAAPT(0)T(0)FGS(0)LDELAPPRPLAR 13 3 1017.1847 0.22514 0 0 0 0 0 0 0 0 3339 1577 589 589 484;4809 549;5459 45863 28041 Mix4_TiO2_1_3 6131 45876 28062 Mix4_TiO2_Reinj_1_5 6921 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.996921 25.2813 0.996921 25.2813 6.2808E-12 166.12 0.634616 2.70425 9.21503E-05 99.222 0.480252 -0.329482 5.24717E-31 232.36 0.0396641 -13.7976 0.11576 43.91 0.960444 14.2762 3.4958E-05 111.02 0.644503 3.57826 1.24564E-05 115.66 1 T GRRASDTSLTQGI 5.24717E-31 232.36 _RASDpTSLTQGIVAFR_ RASDT(0.997)S(0.003)LTQGIVAFR RAS(-42.4)DT(25.28)S(-25.28)LT(-41.76)QGIVAFR 5 2 851.41963 0.18644 4151200 2971900 70370 0 0 0 1068900 40075 3340 1577 592 592 484;4809 549;5459 45868 28053 Mix4_TiO2_1_6 5033 45876 28062 Mix4_TiO2_Reinj_1_5 6921 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.308909 0.811253 0.308909 0.811253 6.2808E-12 166.12 0.0824226 -9.60594 9.21503E-05 99.222 0.000160277 -37.6878 5.24717E-31 232.36 0.00117917 -29.0658 0.11576 43.91 0.0199711 -16.023 3.4958E-05 111.02 0.00343009 -22.0778 1.24564E-05 115.66 1 T ASDTSLTQGIVAF FHA2 Rad53p 0.114 5.24717E-31 232.36 _RASDTSLpTQGIVAFR_ RAS(0.179)DT(0.256)S(0.256)LT(0.309)QGIVAFR RAS(-2.38)DT(-0.81)S(-0.81)LT(0.81)QGIVAFR 8 3 567.94884 0.11266 0 0 0 0 0 0 0 0 3341 1577 484 484 4909 5581;5582 47099 28795 Mix4_TiO2_Reinj_1_5 5899 47099 28795 Mix4_TiO2_Reinj_1_5 5899 Q9H0K1 Q9H0K1 Q9H0K1 >sp|Q9H0K1|SIK2_HUMAN Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1 0.548963 2.82276 0 0 0.548963 2.82276 3.60708E-06 102.08 1 T SGQRRHTLSEVTN AURORA;AURORA-1;AURORA-A;CAMK2;CK2;PKA;PKA/AKT 0.00111111 3.60708E-06 102.08 _RHpTLSEVTNQLVVM(ox)PGAGK_ RHT(0.549)LS(0.287)EVT(0.164)NQLVVMPGAGK RHT(2.82)LS(-2.82)EVT(-5.24)NQLVVMPGAGK 3 3 711.68892 0.6767 465120 0 0 0 465120 0 0 0 3342 1580 291 291 2059 2333 18885 11525 Mix4_TiO2_Reinj_1_1 5244 18885 11525 Mix4_TiO2_Reinj_1_1 5244 Q9H1A4 Q9H1A4 Q9H1A4 >sp|Q9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 OS=Homo sapiens GN=ANAPC1 PE=1 SV=1 0.999625 34.844 0.966949 20.105 0.930383 28.423 0.999625 34.844 0.000488565 83.177 0 0 0 0 1 T FSEQGGTPQNVAT Proline-directed 0.05 0.000488565 83.177 _FSEQGGpTPQNVATSSSLTAHLR_ FSEQGGT(1)PQNVATSSSLTAHLR FS(-50.66)EQGGT(34.84)PQNVAT(-34.84)S(-48.49)S(-54.62)S(-47.72)LT(-53.89)AHLR 7 3 790.03582 0.57888 190960 28805 0 0 162160 0 0 0 3343 1582 179 179 595;596;3492 684;685;3943;3944 32986 20426 Mix4_InSol_Tio2_Reinj_1 3673 32985 20425 Mix4_InSol_TiO2_1 3678 Q9H1E3;Q9H1E3-2 Q9H1E3 Q9H1E3 >sp|Q9H1E3|NUCKS_HUMAN Nuclear ubiquitous casein and cyclin-dependent kinases substrate OS=Homo sapiens GN=NUCKS1 PE=1 SV=1;>sp|Q9H1E3-2|NUCKS_HUMAN Isoform 2 of Nuclear ubiquitous casein and cyclin-dependent kinases substrate OS=Homo sapiens GN=NUCKS1 0.991162 20.4979 0.0122982 -19.0472 0.108447 38.166 0.111474 -8.43277 0.734355 8.4328 0.0227305 -16.2318 0.00334986 72.795 0.80538 6.16811 0.0109045 72.184 0.991162 20.4979 0.0831201 43.346 2 T RLKATVTPSPVKG Proline-directed 0.05 0.0109045 72.184 _LKATVpTPpSPVKGK_ LKAT(0.009)VT(0.991)PS(1)PVKGK LKAT(-20.5)VT(20.5)PS(43.35)PVKGK 6 2 743.37752 0.79109 116550 0 0 0 0 0 63046 53507 3344 1586 551 551 1309;1310 1476;1479 12272 7504 Mix4_TiO2_1_1 5991 12233 7483 Mix4_TiO2_1_1 5580 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.597521 4.34239 0.597521 4.34239 0.00154771 80.715 0 0 0.391916 -0.275294 0.131088 75.832 0 0 0 0 0 0 1 T TSDVIGTCEAADV FHA KAPP 0.155 0.00154771 80.715 _DVISNTSDVIGpTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQK_ DVIS(0.002)NT(0.005)S(0.005)DVIGT(0.598)CEAADVAQKVDEDS(0.22)AEDT(0.085)QS(0.085)NDGKEVVEVGQK DVIS(-24.29)NT(-20.7)S(-20.52)DVIGT(4.34)CEAADVAQKVDEDS(-4.34)AEDT(-8.47)QS(-8.47)NDGKEVVEVGQK 12 4 1183.7789 -0.3764 291460 0.010062 291460 0 0 0 0 0 0 3345 1586 569 569 1309;1310;6356;6357 1476;1479;7269;7271;7272 64177 39376 Mix4_TiO2_Reinj_1_1 3611 64178 39377 Mix4_TiO2_Reinj_1_1 3637 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.918821 10.5465 0.620811 2.14104 3.5812E-17 141.26 0.64517 2.60074 3.19507E-11 120.47 0.918821 10.5465 1.07988E-17 152.03 0.0202545 -16.8454 0.0133962 65.648 0 0 0 0 1 T EDSAEDTQSNDGK 1.07988E-17 152.03 _VDEDSAEDpTQSNDGKEVVEVGQK_ VDEDSAEDT(0.919)QS(0.081)NDGKEVVEVGQK VDEDS(-37.57)AEDT(10.55)QS(-10.55)NDGKEVVEVGQK 9 3 853.3641 -0.76086 9749700 0.19974 2041900 108630 0 7599100 0 0 0 3346 1586 820 820 2943 3349 28072 17447 Mix4_TiO2_1_5 3174 28072 17447 Mix4_TiO2_1_5 3174 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.599795 1.75725 0.599795 1.75725 0.00739498 76.353 0 0 0.000179346 -37.3346 0.013113 69.561 0 0 1 T TDSDSKTEELRFL FHA2 Rad53p 0.114 0.00739498 76.353 _IVTDSDSKpTEELR_ IVTDSDS(0.4)KT(0.6)EELR IVT(-76.35)DS(-51.16)DS(-1.76)KT(1.76)EELR 9 2 786.86127 0.6901 28277 0.17637 28277 0 0 0 0 0 0 3347 1586 193 193 4838 5496;5497;5498 46256 28282 Mix4_TiO2_Reinj_1_1 8463 46222 28252 Mix4_TiO2_Reinj_1_1 7013 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.868772 8.30245 0.622063 2.17522 5.82647E-24 162.75 0.585223 1.7308 1.36234E-05 98.42 0.868772 8.30245 7.69469E-25 174.21 0 0 0 0 1 T RDSFIGTPYWMAP Proline-directed 0.05 7.69469E-25 174.21 _RDSFIGpTPYWMAPEVVMCETSK_ RDS(0.128)FIGT(0.869)PY(0.003)WMAPEVVMCETSK RDS(-8.3)FIGT(8.3)PY(-24.92)WMAPEVVMCET(-109.69)S(-109.69)K 7 3 895.39134 -0.12934 1871900 842380 109390 0 920170 0 0 0 3348 1586 774 774 6039 6888 59675 36213 Mix4_TiO2_Reinj_1_1 3358 59671 36207 Mix4_InSol_Tio2_Reinj_1 4119 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.681481 6.81938 3.84992E-08 -74.1331 4.45482E-05 120.87 0 0 0.681481 6.81938 1.91081E-05 131.63 0.00241643 -25.0787 3.98226E-05 122.87 1.32474E-09 -88.7734 5.40332E-06 137.87 1 T SSFLSKTKDSGSI FHA KAPP;NEK6 0.076 5.40332E-06 137.87 _pTKDSGSISLQETR_ T(0.681)KDS(0.142)GS(0.142)IS(0.034)LQET(0.001)R T(6.82)KDS(-6.82)GS(-6.82)IS(-13.07)LQET(-26.81)R 1 3 501.23465 0.50577 121900 0 0 0 121900 0 0 0 3349 1589 873 873 2067 2342 18948 11557 Mix4_TiO2_Reinj_2_1 5455 18947 11556 Mix4_TiO2_Reinj_1_6 7660 Q9H2M9 Q9H2M9 Q9H2M9 >sp|Q9H2M9|RBGPR_HUMAN Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens GN=RAB3GAP2 PE=1 SV=1 0.392142 0.802427 0.0409837 -13.6573 9.33784E-19 152.97 0.392142 0.802427 0.000259631 81.518 1 T ADSEALTDSWEAL 9.33784E-19 152.97 _FSQTVLGADSEALpTDSWEALSLDTEYWK_ FSQTVLGADS(0.272)EALT(0.392)DS(0.326)WEALS(0.01)LDTEYWK FS(-46.2)QT(-46.61)VLGADS(-1.6)EALT(0.8)DS(-0.8)WEALS(-15.88)LDT(-34.51)EY(-52.16)WK 14 3 1081.4866 -0.56147 0 0 0 0 0 0 0 0 3350 1592 360 360 601 692 5743 3392 Mix4_TiO2_1_3 2823 5748 3398 Mix4_TiO2_Reinj_1_5 3504 Q9H2X6;Q9H2X6-3;Q9H2X6-2;Q86Z02;Q86Z02-2 Q9H2X6 Q9H2X6 >sp|Q9H2X6|HIPK2_HUMAN Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2 PE=1 SV=2;>sp|Q9H2X6-3|HIPK2_HUMAN Isoform 3 of Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2;>sp|Q9H2X6-2|HIPK2_HUMAN Isoform 2 of Homeodomain-int 0.498729 0 0.498729 0 0.0026602 103.72 0 0 0.364879 0.510761 0.00428514 112.75 0 0 0.00756908 -21.1736 0.00187381 99.345 0.000348162 -34.5805 0.00428514 112.75 1 T SKAVCSTYLQSRY 0.00428514 112.75 _AVCSpTYLQSR_ AVCS(0.003)T(0.499)Y(0.499)LQSR AVCS(-22.93)T(0)Y(0)LQS(-77.23)R 5 2 632.77322 0.46709 0 0 0 0 0 0 0 0 3351 1593 334 334 2176 2464 20011 12324 Mix4_TiO2_1_5 4584 20015 12328 Mix4_TiO2_Reinj_1_5 5223 Q9H330;Q9H330-2;Q9H330-4 Q9H330 Q9H330 >sp|Q9H330|CI005_HUMAN Transmembrane protein C9orf5 OS=Homo sapiens GN=C9orf5 PE=1 SV=2;>sp|Q9H330-2|CI005_HUMAN Isoform 2 of Transmembrane protein C9orf5 OS=Homo sapiens GN=C9orf5;>sp|Q9H330-4|CI005_HUMAN Isoform 4 of Transmembrane protein C9orf5 OS=Homo 0.616357 2.09818 0.616357 2.09818 1.73838E-12 133.36 0 0 0.580043 1.42561 2.81288E-18 148.62 0 0 0 0 1 T PTSPSPTLGRRRP 2.81288E-18 148.62 _GESAPTLSTSPSPSSPSPTSPSPpTLGR_ GESAPTLSTSPSPSSPSPTS(0.003)PS(0.38)PT(0.616)LGR GES(-121.55)APT(-130.06)LS(-121.94)T(-121.94)S(-119.15)PS(-93.33)PS(-68.01)S(-70.45)PS(-42.06)PT(-36.37)S(-22.76)PS(-2.1)PT(2.1)LGR 24 2 1331.6158 0.32705 3419100 928360 0 0 2490800 0 0 0 3352 1597 11 11 5476 6232 53405 32627 Mix4_TiO2_1_6 6339 53406 32628 Mix4_TiO2_Reinj_1_6 7180 Q9H3Z4;Q9H3Z4-2 Q9H3Z4 Q9H3Z4 >sp|Q9H3Z4|DNJC5_HUMAN DnaJ homolog subfamily C member 5 OS=Homo sapiens GN=DNAJC5 PE=1 SV=1;>sp|Q9H3Z4-2|DNJC5_HUMAN Isoform 2 of DnaJ homolog subfamily C member 5 OS=Homo sapiens GN=DNAJC5 0.281846 0 0.281846 0 0.20364 39.471 0.0207067 -16.1516 0.0143433 68.984 1 T RQRSLSTSGESLY CK1;CK2 0.081 0.0143433 68.984 _SLSpTSGESLYHVLGLDK_ S(0.195)LS(0.234)T(0.282)S(0.282)GES(0.007)LYHVLGLDK S(-1.6)LS(-0.8)T(0)S(0)GES(-16.09)LY(-39.47)HVLGLDK 4 2 943.45079 0.040289 0 0 0 0 0 0 0 0 3353 1599 26 26 3015;6821 3429;7805 69143 42387 Mix4_InSol_TiO2_1 4362 28788 17925 Mix4_TiO2_Reinj_1_4 3710 Q9H4B6 Q9H4B6 Q9H4B6 >sp|Q9H4B6|SAV1_HUMAN Protein salvador homolog 1 OS=Homo sapiens GN=SAV1 PE=1 SV=2 0.492619 0 0.000568964 -32.4467 0.0473063 56.318 0 0 3.33706E-05 -44.7662 0.00399662 90.481 0.492619 0 0.438646 15.233 0 0 1 T KYVKKETSPLLRN FHA2 Rad53p 0.114 0.00399662 90.481 _YVKKEpTSPLLR_ Y(0.015)VKKET(0.493)S(0.493)PLLR Y(-15.23)VKKET(0)S(0)PLLR 6 3 471.92157 -0.24902 0 0 0 0 0 0 0 0 3354 1601 249 249 6312;6313;6314 7212;7213;7214 63148 38489 Mix4_TiO2_1_6 4950 63150 38491 Mix4_TiO2_Reinj_1_5 6723 Q9H4L5;Q9H4L5-5;Q9H4L5-3;Q9H4L5-7 Q9H4L5 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3 PE=1 SV=1;>sp|Q9H4L5-5|OSBL3_HUMAN Isoform 2a of Oxysterol-binding protein-related protein 3 OS=Homo sapiens GN=OSBPL3;>sp|Q9H4L5-3|OSBL3_HUMAN Isoform 1c of Oxyst 0.879496 8.67579 0.879496 8.67579 1.17698E-15 145.6 0 0 0.861548 7.94159 4.36244E-16 152.56 0.0498841 -9.27463 1.71476 9.2746 0.120107 -6.36079 1.59392 6.3608 1 T MDVLHRTYSAPAI FHA KAPP;NEK6 0.076 4.36244E-16 152.56 _pTYSAPAINAIQGGSFESPK_ T(0.879)Y(0.001)S(0.119)APAINAIQGGSFESPK T(8.68)Y(-29.93)S(-8.68)APAINAIQGGS(-37.58)FES(-37.58)PK 1 2 1009.467 -0.29135 361360 14157 0 0 347200 0 0 0 3355 1605 298 298 315 358 2963 1803 Mix4_TiO2_Reinj_1_4 4230 2962 1802 Mix4_TiO2_Reinj_1_4 4191 Q9H6S1 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1 0.275313 0 1.79057E-05 -46.8093 0.000680924 94.823 0 0 0.275313 0 6.17919E-05 105.51 0.075438 -9.94201 0.055772 54.685 0.00663366 -21.0721 0.0321226 58.942 1 T GKALCHTTSSPLP FHA KAPP;NEK6 0.076 6.17919E-05 105.51 _ALCHpTTSSPLPGDVK_ ALCHT(0.275)T(0.275)S(0.234)S(0.215)PLPGDVK ALCHT(0)T(0)S(-0.7)S(-1.07)PLPGDVK 5 3 554.92342 0.99287 0 0 0 0 0 0 0 0 3356 1605 299 299 315 358 2963 1803 Mix4_TiO2_Reinj_1_4 4230 2962 1802 Mix4_TiO2_Reinj_1_4 4191 Q9H6S1 Q9H6S1 Q9H6S1 >sp|Q9H6S1|AZI2_HUMAN 5-azacytidine-induced protein 2 OS=Homo sapiens GN=AZI2 PE=1 SV=1 0.275313 0 0.000513032 -32.2377 0.000680924 94.823 0 0 0.275313 0 6.17919E-05 105.51 0.0748901 -7.5749 0.055772 54.685 0.0181338 -16.8987 0.0321226 58.942 1 T KALCHTTSSPLPG 6.17919E-05 105.51 _ALCHpTTSSPLPGDVK_ ALCHT(0.275)T(0.275)S(0.234)S(0.215)PLPGDVK ALCHT(0)T(0)S(-0.7)S(-1.07)PLPGDVK 6 3 554.92342 0.99287 0 0 0 0 0 0 0 0 3357 1609 1800 1800 6093 6954 60228 36472 Mix4_InSol_Tio2_Reinj_1 6774 60230 36475 Mix4_TiO2_Reinj_1_5 6253 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.837961 7.8073 0 0 0 0 0.268693 -1.29093 1.54596E-34 185.84 0.263727 -1.01249 4.92054E-07 106.64 0.837961 7.8073 1.71419E-11 124.43 1 T TPKATRTLSSPSL FHA KAPP 0.155 1.54596E-34 185.84 _pTLSSPSLQTDGIAATPVPPPPPPK_ T(0.838)LS(0.139)S(0.019)PS(0.004)LQT(0.001)DGIAATPVPPPPPPK T(7.81)LS(-7.81)S(-16.45)PS(-23.78)LQT(-30.57)DGIAAT(-90.46)PVPPPPPPK 1 3 816.75225 1.5597 262680 0 0 0 0 0 0 262680 3358 1609 1808 1808 6093 6954 60230 36475 Mix4_TiO2_Reinj_1_5 6253 60230 36475 Mix4_TiO2_Reinj_1_5 6253 Q9H7D0 Q9H7D0 Q9H7D0 >sp|Q9H7D0|DOCK5_HUMAN Dedicator of cytokinesis protein 5 OS=Homo sapiens GN=DOCK5 PE=1 SV=3 0.92754 15.6381 0 0 0 0 0.92754 15.6381 1.54596E-34 185.84 0.0170692 -12.9019 4.92054E-07 106.64 0.0460691 -7.55079 1.71419E-11 124.43 1 T SSPSLQTDGIAAT CK1;FHA2 Rad53p 0.081 1.54596E-34 185.84 _TLSSPSLQpTDGIAATPVPPPPPPK_ T(0.012)LS(0.017)S(0.018)PS(0.025)LQT(0.928)DGIAATPVPPPPPPK T(-18.73)LS(-17.38)S(-17.18)PS(-15.64)LQT(15.64)DGIAAT(-120.07)PVPPPPPPK 9 3 816.75225 0.80771 361600 0 0 0 361600 0 0 0 3359 1614 29 29 6097 6959 60270 36487 Mix4_TiO2_1_2 2643 60271 36488 Mix4_TiO2_Reinj_1_2 3321 Q9H8T0-2;Q9H8T0 Q9H8T0-2 Q9H8T0-2 >sp|Q9H8T0-2|AKTIP_HUMAN Isoform 2 of AKT-interacting protein OS=Homo sapiens GN=AKTIP;>sp|Q9H8T0|AKTIP_HUMAN AKT-interacting protein OS=Homo sapiens GN=AKTIP PE=1 SV=1 0.622617 2.32367 0.622617 2.32367 0.364145 19.897 0 0 0.594181 1.65589 0.0292686 56.817 1 T LTGDVKTSPPRTA 0.0292686 56.817 _TLTGDVKpTSPPR_ T(0.006)LT(0.006)GDVKT(0.623)S(0.365)PPR T(-19.9)LT(-19.9)GDVKT(2.32)S(-2.32)PPR 8 2 676.3345 -0.11789 72990 21820 0 0 51170 0 0 0 3360 1621 920 920 307 350 2888 1757 Mix4_TiO2_Reinj_1_5 6912 2888 1757 Mix4_TiO2_Reinj_1_5 6912 Q9HAU0-4;Q9HAU0-2;Q9HAU0;Q9HAU0-5 Q9HAU0-4 Q9HAU0-4 >sp|Q9HAU0-4|PKHA5_HUMAN Isoform 4 of Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens GN=PLEKHA5;>sp|Q9HAU0-2|PKHA5_HUMAN Isoform 2 of Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens GN=PLEKHA5;>sp|Q9HAU0|PKH 0.477994 0 0.122618 -8.19137 0.320219 36.305 0.477994 0 0.00148055 80.855 0 0 0.159716 -3.06384 1.06526 14.348 1 T PRAKSPTPESSTI FHA KAPP;Proline-directed 0.05 0.00148055 80.855 _AKpSPTPESSTIASYVTLR_ AKS(0.478)PT(0.478)PES(0.015)S(0.015)T(0.015)IASYVTLR AKS(0)PT(0)PES(-15.13)S(-15.13)T(-15.13)IAS(-80.86)Y(-80.86)VT(-80.86)LR 5 3 663.32939 -0.10655 0 0 0 0 0 0 0 0 3361 1645 145 145 0 0;1;2;3;4 9 4 Mix4_TiO2_1_5 5157 19 9 Mix4_TiO2_Reinj_1_5 6475 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.386855 1.02284 0.386855 1.02284 0.0046668 76.982 0.157272 -7.17308 3.47748E-12 126.64 0 0 0.0324293 -14.6241 0.000107956 91.637 2 T AAPSSPTPESPTM CK1;FHA KAPP;Proline-directed 0.05 3.47748E-12 126.64 _AAAAAAAATM(ox)ALAAPSSPpTPESPpTM(ox)LTK_ AAAAAAAATMALAAPS(0.307)S(0.307)PT(0.387)PES(0.096)PT(0.753)MLT(0.15)K AAAAAAAAT(-37.28)MALAAPS(-1.02)S(-1.02)PT(1.02)PES(-8.97)PT(7.02)MLT(-7.02)K 19 3 931.08255 -0.42964 0 0 0 0 0 0 0 0 3362 1645 150 150 0 0;1;2;3;4 5 3 Mix4_TiO2_Reinj_1_5 5919 4 2 Mix4_TiO2_Reinj_1_5 5788 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.844148 7.84965 0.753176 7.01795 0.0046668 76.982 0.844148 7.84965 1.742E-18 149.73 0 0 5.82035E-05 -42.084 0.000107956 91.637 1 T PTPESPTMLTKKP 1.742E-18 149.73 _AAAAAAAATM(ox)ALAAPSSPTPESPpTM(ox)LTK_ AAAAAAAATMALAAPSSPTPES(0.139)PT(0.844)MLT(0.017)K AAAAAAAAT(-138.14)MALAAPS(-110.53)S(-91.53)PT(-55.05)PES(-7.85)PT(7.85)MLT(-16.87)K 24 3 904.4271 -0.11908 397100 0 0 0 397100 0 0 0 3363 1645 153 153 0 0;1;2;3;4 10 5 Mix4_TiO2_Reinj_1_5 5744 19 9 Mix4_TiO2_Reinj_1_5 6475 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.739476 7.17308 0.150498 -7.01795 0.0046668 76.982 0.739476 7.17308 3.47748E-12 126.64 0 0 6.784E-05 -41.4187 0.000107956 91.637 2 T ESPTMLTKKPEDN 3.47748E-12 126.64 _AAAAAAAATM(ox)ALAAPSpSPTPESPTM(ox)LpTK_ AAAAAAAATMALAAPS(0.039)S(0.804)PT(0.157)PES(0.116)PT(0.143)MLT(0.739)K AAAAAAAAT(-59.16)MALAAPS(-13.25)S(7.17)PT(-7.17)PES(-8.1)PT(-7.17)MLT(7.17)K 27 3 931.08255 -0.91032 430280 0 0 0 430280 0 0 0 3364 1645 424 424 4404 5010 41951 25866 Mix4_TiO2_Reinj_1_5 2543 41951 25866 Mix4_TiO2_Reinj_1_5 2543 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.871707 8.32167 0.397494 -1.8058 6.75721E-13 149 0.871707 8.32167 2.85166E-16 165.13 1 T AASSPETPSAGQQ CK1;ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.000145 2.85166E-16 165.13 _PAASSPEpTPSAGQQEAK_ PAASSPET(0.872)PS(0.128)AGQQEAK PAAS(-101.13)S(-69.1)PET(8.32)PS(-8.32)AGQQEAK 8 2 868.38036 -0.17746 1526300 12.054 0 0 0 1526300 0 0 0 3365 1645 478 478 5405;6158 6151;6152;7030 52671 32196 Mix4_TiO2_Reinj_1_5 1557 52671 32196 Mix4_TiO2_Reinj_1_5 1557 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.999448 32.7098 0.998281 28.2353 0.0026718 93.327 0.000344194 -31.6197 0.117988 36.582 0.999448 32.7098 0.00198172 95.803 0.993387 22.6545 0.0135277 66.86 0.996045 24.9883 0.0113073 70.871 2 T QPPRSKTPSSPCP CAMK2;FHA KAPP;PKA/AKT;Proline-directed 0.00111111 0.00198172 95.803 _SKpTPSpSPCPASK_ S(0.001)KT(0.999)PS(0.001)S(0.999)PCPASK S(-32.71)KT(32.71)PS(-28.86)S(28.86)PCPAS(-42.05)K 3 2 703.77478 0.16197 326770 28282 0 0 207840 0 39274 51378 3366 1645 298 298 5947 6781;6782 58595 35530 Mix4_TiO2_1_5 4090 58599 35535 Mix4_TiO2_Reinj_1_5 4739 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.415202 0 0.415202 0 0.000488299 82.428 0.127716 -6.70554 1.53242 22.288 0.0832326 -9.6167 0.000280337 89.423 0 0 0.232469 2.59421 0.00832403 71.891 0.162716 -5.22611 1.69174 17.217 1 T TPTGSRTDSQSVR 0.000280337 89.423 _pTDSQSVRHSPIAPSSPSPQVLAQK_ T(0.415)DS(0.415)QS(0.072)VRHS(0.072)PIAPS(0.02)S(0.004)PS(0.001)PQVLAQK T(0)DS(0)QS(-7.58)VRHS(-7.58)PIAPS(-13.13)S(-20.38)PS(-27.88)PQVLAQK 1 4 650.07344 0.1182 0 0 0 0 0 0 0 0 3367 1645 207 207 6090;6091;6092 6947;6948;6949;6950;6951;6952;6953 60186 36453 Mix4_TiO2_Reinj_1_4 2779 60187 36454 Mix4_TiO2_Reinj_1_5 4935 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.210173 4.3834 0.0457005 -12.1225 0.0927161 58.626 0.000477914 -32.2661 0.609207 44.44 0.210173 4.3834 1.95833E-07 103.16 0.0121694 -12.198 1.88037 21.485 0.0152694 -13.5583 1.29816 31.478 2 T ASATAPTSQGIPT 1.95833E-07 103.16 _TLSPTPApSATAPpTSQGIPTSDEESTPK_ T(0.176)LS(0.176)PT(0.176)PAS(0.209)AT(0.175)APT(0.21)S(0.176)QGIPT(0.175)S(0.175)DEES(0.175)T(0.175)PK T(-4.38)LS(-4.38)PT(-4.38)PAS(4.38)AT(-4.56)APT(4.38)S(-4.38)QGIPT(-4.56)S(-4.56)DEES(-4.56)T(-4.56)PK 13 2 1416.1172 1.0925 0 0 0 0 0 0 0 0 3368 1645 213 213 6090;6091;6092 6947;6948;6949;6950;6951;6952;6953 60187 36454 Mix4_TiO2_Reinj_1_5 4935 60187 36454 Mix4_TiO2_Reinj_1_5 4935 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.523919 2.8908 0.48253 0 0.0209443 65.076 0.495334 0 2.09978E-07 98.942 0.523919 2.8908 1.95833E-07 103.16 0.24693 0 1.88037 21.485 0.346459 0 1.29816 31.478 2 T TSQGIPTSDEEST CK2 0.117 1.95833E-07 103.16 _TLSPTPASATAPTSQGIPpTpSDEESTPK_ TLSPT(0.011)PAS(0.28)AT(0.042)APT(0.033)S(0.033)QGIPT(0.524)S(0.612)DEES(0.232)T(0.232)PK T(-39.51)LS(-31.96)PT(-17.2)PAS(-2.89)AT(-11.15)APT(-12.19)S(-12.19)QGIPT(2.89)S(5.06)DEES(-5.06)T(-5.06)PK 19 3 944.4139 0.19979 1376400 0 0 0 1376400 0 0 0 3369 1645 219 219 6090;6091;6092 6947;6948;6949;6950;6951;6952;6953 60200 36462 Mix4_TiO2_2_2 3902 60173 36451 Mix4_TiO2_Reinj_1_5 5003 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.805307 10.9661 0.835054 7.02615 0.0209443 65.076 0.805307 10.9661 0.609207 44.44 0.50029 0 0.000240279 82.134 0.24693 0 1.88037 21.485 0.135951 -4.06268 1.29816 31.478 1 T TSDEESTPKKSKA CDK1;CDK2;Polo box;Proline-directed 0.00405 6.92169E-12 121.33 _TLSPTPASATAPTSQGIPTSDEESpTPKK_ TLSPTPASATAPTSQGIPT(0.064)S(0.064)DEES(0.064)T(0.805)PKK T(-44.44)LS(-44.44)PT(-44.44)PAS(-38.3)AT(-38.06)APT(-32.27)S(-32.27)QGIPT(-10.97)S(-10.97)DEES(-10.97)T(10.97)PKK 25 3 960.45677 0.30697 101280 0 101280 0 0 0 0 0 3370 1645 292 292 6457 7386 65218 39996 Mix4_InSol_Tio2_Reinj_1 7989 65221 40000 Mix4_TiO2_Reinj_1_5 7433 Q9NQS7;Q9NQS7-2 Q9NQS7 Q9NQS7 >sp|Q9NQS7|INCE_HUMAN Inner centromere protein OS=Homo sapiens GN=INCENP PE=1 SV=3;>sp|Q9NQS7-2|INCE_HUMAN Isoform 2 of Inner centromere protein OS=Homo sapiens GN=INCENP 0.723743 7.15395 0.488235 0 0.000739364 91.817 0 0 0.418284 1.9182 5.05277E-05 98.439 0.237724 -2.57777 0.013505 69.678 0.723743 7.15395 0.00267325 78.961 1 T LPDNFSTPTGSRT Polo box;Proline-directed 0.00405 5.05277E-05 98.439 _VLAPILPDNFSpTPTGSR_ VLAPILPDNFS(0.021)T(0.724)PT(0.116)GS(0.139)R VLAPILPDNFS(-15.35)T(7.15)PT(-7.96)GS(-7.15)R 12 2 932.96387 -0.12636 147400 0 0 0 0 0 0 147400 3371 1646 326 326 453 515 4208 2519 Mix4_TiO2_1_3 5873 4209 2520 Mix4_TiO2_Reinj_1_3 6666 Q9NQU5 Q9NQU5 Q9NQU5 >sp|Q9NQU5|PAK6_HUMAN Serine/threonine-protein kinase PAK 6 OS=Homo sapiens GN=PAK6 PE=1 SV=1 0.323337 0 0.323337 0 1.17718E-07 112.4 0.0208526 -15.9638 5.30499E-12 129.46 0.0202458 -16.1526 3.81861E-07 99.575 0.140415 -6.90334 4.88684E-05 96.098 1 T PLTTSDTSSPQKS 5.30499E-12 129.46 _AQSLPSDQPVGTFSPLTTSDpTSSPQK_ AQSLPSDQPVGTFSPLT(0.001)T(0.001)S(0.027)DT(0.323)S(0.323)S(0.323)PQK AQS(-81.67)LPS(-81.67)DQPVGT(-52.23)FS(-40.96)PLT(-23.54)T(-24.32)S(-10.73)DT(0)S(0)S(0)PQK 21 2 1378.6368 0.46397 0 0 0 0 0 0 0 0 3372 1656 279 279 5579;6147 6358;7019 60904 36903 Mix4_TiO2_Reinj_1_5 4834 54592 33421 Mix4_TiO2_Reinj_1_5 5310 Q9NRM7 Q9NRM7 Q9NRM7 >sp|Q9NRM7|LATS2_HUMAN Serine/threonine-protein kinase LATS2 OS=Homo sapiens GN=LATS2 PE=1 SV=2 0.999934 41.801 0.991621 20.7313 0.00455059 78.446 0.999934 41.801 1.49063E-11 133.74 1 T PSFQSKTPPETGG CK2;Proline-directed 0.05 1.49063E-11 133.74 _pTPPETGGYASLPTK_ T(1)PPETGGYASLPTK T(41.8)PPET(-41.8)GGY(-73.66)AS(-70.32)LPT(-75.1)K 1 2 749.8449 0.24857 125150 21928 0 0 103230 0 0 0 3373 1663 829 829 1173;5324 1318;6060 51677 31641 Mix4_TiO2_1_5 8451 51673 31635 Mix4_TiO2_1_3 8793 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.468089 0 0.468089 0 3.56751E-26 162.1 0.425753 0 3.06584E-12 123.45 0.359069 0 2.05497E-18 143.46 0.347163 0 2.01161E-12 128.24 1 T RSGSGPTQDLNTI CK1;FHA2 Rad53p 0.081 3.56751E-26 162.1 _SGpSGPTQDLNTILLTSAQLSSDVAVETPK_ S(0.064)GS(0.468)GPT(0.468)QDLNTILLTSAQLSSDVAVETPK S(-8.66)GS(0)GPT(0)QDLNT(-42.66)ILLT(-80.48)S(-80.16)AQLS(-89.62)S(-98.16)DVAVET(-98.16)PK 6 2 1505.2368 0.17918 0 0 0 0 0 0 0 0 3374 1663 834 834 1173;5324 1318;6060 51691 31657 Mix4_TiO2_Reinj_1_6 7681 51673 31635 Mix4_TiO2_1_3 8793 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.356547 1.67661 0.317405 1.57943 3.56751E-26 162.1 0.24596 0 3.06584E-12 123.45 0.356547 1.67661 2.05497E-18 143.46 0.178278 -1.84807 2.01161E-12 128.24 1 T PTQDLNTILLTSA FHA2 Rad53p 0.114 3.56751E-26 162.1 _SGSGPTQDLNpTILLTSAQLSSDVAVETPK_ S(0.2)GS(0.2)GPT(0.242)QDLNT(0.357)ILLTSAQLSSDVAVETPK S(-2.5)GS(-2.5)GPT(-1.68)QDLNT(1.68)ILLT(-30.89)S(-54.27)AQLS(-91.68)S(-98.39)DVAVET(-118.93)PK 11 3 1003.827 0.30809 0 0 0 0 0 0 0 0 3375 1663 838 838 1173;5324 1318;6060 10974 6727 Mix4_TiO2_1_5 8405 51673 31635 Mix4_TiO2_1_3 8793 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.185566 0 0.185566 0 3.56751E-26 162.1 0.0130809 -12.7423 3.06584E-12 123.45 0.000290492 -30.8898 2.05497E-18 143.46 0.00278371 -19.9128 2.01161E-12 128.24 1 T LNTILLTSAQLSS 3.56751E-26 162.1 _DRSGSGPTQDLNTILLpTSAQLSSDVAVETPK_ DRS(0.157)GS(0.157)GPT(0.157)QDLNT(0.157)ILLT(0.186)S(0.186)AQLS(0.002)SDVAVETPK DRS(-0.74)GS(-0.74)GPT(-0.74)QDLNT(-0.74)ILLT(0)S(0)AQLS(-20.06)S(-26)DVAVET(-44.29)PK 17 3 1094.203 0.27239 0 0 0 0 0 0 0 0 3376 1663 727 727 3246 3680 30702 19064 Mix4_InSol_Tio2_Reinj_1 2134 30703 19065 Mix4_TiO2_Reinj_1_5 1926 Q9NSY1 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2 0.5 0 0 0 0.000173836 -37.5978 0.000833441 80.949 0.0159728 -17.8963 0.203141 29.526 0.5 0 0.432853 15.843 1 T QRTGKKTSVQGQV 0.000833441 80.949 _KpTSVQGQVQK_ KT(0.5)S(0.5)VQGQVQK KT(0)S(0)VQGQVQK 2 2 591.79755 0.18511 10113 0 0 0 0 0 0 10113 3377 1663 1011 1011 6067 6921 59900 36321 Mix4_InSol_Tio2_Reinj_1 3605 59900 36321 Mix4_InSol_Tio2_Reinj_1 3605 Q9NSY1;Q5H9B9 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2;>sp|Q5H9B9|BM2KL_HUMAN Putative BMP-2-inducible kinase-like protein OS=Homo sapiens GN=BMP2KL PE=5 SV=2 0.994151 22.6335 0.681358 3.36875 0.162335 33.554 0.700458 4.29379 0.0638794 44.519 0.790888 6.05665 0.00776395 67.92 0 0 0.41438 2.07758 0.600517 7.6027 0.994151 22.6335 0.00429296 76.459 1 T KKTLKPTYRTPER NEK6 0.076 0.00429296 76.459 _TLKPpTYRTPER_ TLKPT(0.994)YRT(0.005)PER T(-76.46)LKPT(22.63)Y(-33.67)RT(-22.63)PER 5 2 721.36359 0.16863 7586900 79608 23388 0 6250200 0 0 1233600 3378 1663 1014 1014 6067 6921 59906 36340 Mix4_TiO2_2_2 2642 59900 36321 Mix4_InSol_Tio2_Reinj_1 3605 Q9NSY1;Q5H9B9 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2;>sp|Q5H9B9|BM2KL_HUMAN Putative BMP-2-inducible kinase-like protein OS=Homo sapiens GN=BMP2KL PE=5 SV=2 0.9068 10.9873 0.617801 2.82139 0.162335 33.554 0.9068 10.9873 0.0638794 44.519 0.446244 0 0.00776395 67.92 0 0 0.356165 2.19999 0.600517 7.6027 0.281989 0.4142 0.00429296 76.459 1 T LKPTYRTPERARR CDK1;CDK2;Proline-directed 0.0057 0.00429296 76.459 _TLKPTYRpTPER_ TLKPT(0.021)Y(0.072)RT(0.907)PER T(-44.52)LKPT(-16.37)Y(-10.99)RT(10.99)PER 8 3 481.24482 -0.089075 96730 35197 61533 0 0 0 0 0 3379 1664 1370 1370 188;189;449 217;218;219;511 1951 1303 Mix4_TiO2_1_5 3099 1952 1304 Mix4_TiO2_1_5 3277 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.787739 5.70739 0.787739 5.70739 9.03743E-48 241.63 0 0 0.996972 25.5234 3.84787E-11 136.56 0.976433 16.2064 1.49274E-10 124.41 0.434548 -0.64237 0.719382 28.708 1 T IESTQSTPQKGRG CDK1;CDK2;Polo box;Proline-directed 0.00405 9.03743E-48 241.63 _AESPESSAIESTQSpTPQK_ AESPESSAIESTQS(0.212)T(0.788)PQK AES(-59.07)PES(-59.07)S(-59.07)AIES(-35.21)T(-33.42)QS(-5.71)T(5.71)PQK 15 2 978.92533 -0.11577 21739 21739 0 0 0 0 0 0 3380 1664 1381 1381 2417;6157 2739;2740;7029 22594 14094 Mix4_TiO2_Reinj_1_5 1716 22594 14094 Mix4_TiO2_Reinj_1_5 1716 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.998355 29.1816 1.75063E-05 -47.5055 0.104608 47.505 0.998355 29.1816 0.00867864 74.828 0.983392 17.9371 0.0138117 68.731 0.62872 4.13142 0.0514485 51.951 2 T RGRPSKTPSPSQP Proline-directed 0.05 0.00867864 74.828 _GRPSKpTPpSPSQPK_ GRPSKT(0.998)PS(0.981)PS(0.02)QPK GRPS(-33.41)KT(29.18)PS(17.09)PS(-17.09)QPK 6 2 763.84184 0.10271 650600 0 0 0 485930 0 94780 69885 3381 1664 1220 1220 3096 3519 29450 18358 Mix4_TiO2_Reinj_1_5 1622 29449 18357 Mix4_TiO2_Reinj_1_5 1609 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.821777 6.63791 0 0 0.821777 6.63791 0.00249242 85.722 1 T PRGRKKTPVTEQE CAMK2;PKA;PKA/AKT;Proline-directed 0.001764 0.00249242 85.722 _KKpTPVTEQEEK_ KKT(0.822)PVT(0.178)EQEEK KKT(6.64)PVT(-6.64)EQEEK 3 3 466.22884 -0.089002 37823 0 0 0 37823 0 0 0 3382 1664 1223 1223 3096 3519 29449 18357 Mix4_TiO2_Reinj_1_5 1609 29449 18357 Mix4_TiO2_Reinj_1_5 1609 Q9NTI5;Q9NTI5-2 Q9NTI5 Q9NTI5 >sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1;>sp|Q9NTI5-2|PDS5B_HUMAN Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B 0.999905 40.2191 0 0 0.999905 40.2191 0.00249242 85.722 1 T RKKTPVTEQEEKL CK2 0.117 0.00249242 85.722 _KKTPVpTEQEEK_ KKTPVT(1)EQEEK KKT(-40.22)PVT(40.22)EQEEK 6 2 698.83961 -0.060498 100540 0 0 0 100540 0 0 0 3383 1668 488 488 2469 2803;2804 23203 14472 Mix4_TiO2_Reinj_1_4 3018 23203 14472 Mix4_TiO2_Reinj_1_4 3018 Q9NUL3;Q9NUL3-2;Q9NUL3-3;Q9NUL3-4 Q9NUL3 Q9NUL3 >sp|Q9NUL3|STAU2_HUMAN Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2 PE=1 SV=1;>sp|Q9NUL3-2|STAU2_HUMAN Isoform Short of Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens GN=STAU2;>sp|Q9NUL3-3|STAU2_HUMA 0.998953 30.1737 0.483986 2.22106 0.0232851 61.686 0.998953 30.1737 6.22946E-05 105.38 1.51779E-07 -68.1878 0.00663816 76.275 0 0 2 T LKGSSPTPPCSPV CK1;Proline-directed 0.05 6.22946E-05 105.38 _GSSPpTPPCpSPVQPSK_ GSS(0.001)PT(0.999)PPCS(1)PVQPSK GS(-40.57)S(-30.17)PT(30.17)PPCS(65.38)PVQPS(-73.6)K 5 2 843.33573 0.24951 213240 0 0 0 213240 0 0 0 3384 1672 456 456 3767 4251;4252 35639 22027 Mix4_TiO2_1_5 2052 35639 22027 Mix4_TiO2_1_5 2052 Q9NV70-2;Q9NV70 Q9NV70-2 Q9NV70-2 >sp|Q9NV70-2|EXOC1_HUMAN Isoform 2 of Exocyst complex component 1 OS=Homo sapiens GN=EXOC1;>sp|Q9NV70|EXOC1_HUMAN Exocyst complex component 1 OS=Homo sapiens GN=EXOC1 PE=1 SV=4 0.930853 9.18748 0.930853 9.18748 0.0063405 62.303 0 0 0.864569 10.1788 0.072029 40.39 2 T GKLTGSTSSLNKL FHA2 Rad53p 0.114 0.0063405 62.303 _LTGSpTpSSLNK_ LTGST(0.931)S(0.642)S(0.427)LNK LT(-62.3)GS(-40.69)T(9.19)S(2.04)S(-2.04)LNK 5 2 584.23835 0.27605 259820 24386 0 0 235440 0 0 0 3385 1673 3 3 585;586 669;670;671;672;673 5523 3287 Mix4_InSol_TiO2_1 3509 5530 3295 Mix4_TiO2_Reinj_1_4 3073 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.928831 11.1566 0.974743 18.7832 0.0400156 57.981 0.000104927 -38.8473 0.0421029 53.183 0.44812 -0.869887 0.00136366 85.836 0.928831 11.1566 0.008112 76.642 0.877303 8.56759 0.170329 34.065 1 T ____MATSPQKSP 0.00689619 78.838 _(ac)ApTSPQKSPSVPK_ AT(0.929)S(0.071)PQKSPSVPK AT(11.16)S(-11.16)PQKS(-59.51)PS(-66.98)VPK 2 2 674.82905 0.23647 2063100 0 0 0 0 0 1212000 851180 3386 1673 16 16 586;5586;5587;5592 671;672;673;6366;6367;6368;6373;6374 54642 33467 Mix4_TiO2_Reinj_1_2 2699 54640 33464 Mix4_TiO2_1_4 2651 Q9NVD7;Q9NVD7-2 Q9NVD7 Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens GN=PARVA PE=1 SV=1;>sp|Q9NVD7-2|PARVA_HUMAN Isoform 2 of Alpha-parvin OS=Homo sapiens GN=PARVA 0.900717 9.61457 0.834826 7.18287 3.36928E-12 139.43 0.0170424 -17.5711 0.280212 23.465 0.900717 9.61457 0.00136366 85.836 0.401179 -1.78853 0.0357626 58.634 0.525877 -0.756395 0.389168 32.582 2 T SVPKSPTPKSPPS CDK1;CHK1;FHA KAPP;PKD;Proline-directed 0.0057 3.36928E-12 139.43 _SPSVPKSPpTPKpSPPSR_ SPSVPKS(0.099)PT(0.901)PKS(0.874)PPS(0.125)R S(-48.7)PS(-45.08)VPKS(-9.61)PT(9.61)PKS(8.46)PPS(-8.46)R 9 3 603.6163 -0.019199 2943200 289100 0 0 2615200 0 0 38964 3387 1690 31 31 3670 4139 34495 21438 Mix4_TiO2_2_3 3012 34496 21439 Mix4_TiO2_Reinj_1_3 3888 Q9NXF1 Q9NXF1 Q9NXF1 >sp|Q9NXF1|TEX10_HUMAN Testis-expressed sequence 10 protein OS=Homo sapiens GN=TEX10 PE=1 SV=2 0.991634 20.7384 0.897734 9.43418 0.00121405 88.158 0.991634 20.7384 0.0315191 52.12 0.901553 9.61791 0.00145937 92.804 0.938796 11.8579 0.0566287 43.806 0.656 2.80346 0.734792 2.8035 1 T LQNATPTNFKTKT 0.00145937 92.804 _LQNATPpTNFK_ LQNAT(0.008)PT(0.992)NFK LQNAT(-20.74)PT(20.74)NFK 7 2 607.28428 0.36299 914900 107.52 190620 17173 0 645010 0 37780 24321 3388 1695 661 661 2719;4912 3098;5585 25690 15871 Mix4_InSol_Tio2_Reinj_1 6192 25691 15872 Mix4_TiO2_Reinj_1_1 5382 Q9NYF8;Q9NYF8-2;Q9NYF8-3;Q9NYF8-4 Q9NYF8 Q9NYF8 >sp|Q9NYF8|BCLF1_HUMAN Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1 PE=1 SV=2;>sp|Q9NYF8-2|BCLF1_HUMAN Isoform Btf-l of Bcl-2-associated transcription factor 1 OS=Homo sapiens GN=BCLAF1;>sp|Q9NYF8-3|BCLF1_HUMAN Isoform BP-1 of Bcl-2-as 0.726534 5.24191 0 0 0.0552632 -10.0756 0.030734 53.155 0.0712794 -10.6602 0.382785 20.221 0.726534 5.24191 0.508744 15.998 1 T IDISPSTLRKHTR CK1 0.081 0.030734 53.155 _IDISPSpTLR_ IDIS(0.217)PS(0.056)T(0.727)LR IDIS(-5.24)PS(-11.12)T(5.24)LR 7 2 541.2681 0.25268 32419 0 0 0 0 0 0 32419 3389 1696 628 628 6782 7760 68757 42171 Mix4_TiO2_1_3 2893 68760 42175 Mix4_TiO2_Reinj_1_3 3857 Q9NYL2 Q9NYL2 Q9NYL2 >sp|Q9NYL2|MLTK_HUMAN Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2 0.99931 31.6091 0.99931 31.6091 0.00168033 94.762 0 0 0.996662 24.7518 0.000562678 135.36 1.0281E-07 -69.8796 0.00168033 94.762 1.5602E-08 -78.0682 0.00363911 78.068 1 T IKYQQITPVNQSR Proline-directed 0.05 0.000562678 135.36 _YQQIpTPVNQSR_ YQQIT(0.999)PVNQS(0.001)R Y(-76.85)QQIT(31.61)PVNQS(-31.61)R 5 2 707.32975 -0.22847 443200 104370 0 0 338830 0 0 0 3390 1699 692 692 286 326 2690 1671 Mix4_TiO2_1_5 3629 2690 1671 Mix4_TiO2_1_5 3629 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.999989 49.5365 0.999989 49.5365 0.039323 49.536 0 0 0 0 0.99994 42.2006 0.0614788 42.201 0 0 0 0 1 T PEPKAITPPQQPY Proline-directed 0.05 0.039323 49.536 _AIpTPPQQPYK_ AIT(1)PPQQPYK AIT(49.54)PPQQPY(-49.54)K 3 2 611.79702 0.68314 518970 98723 0 0 420250 0 0 0 3391 1699 893 893 3807 4302 36169 22367 Mix4_TiO2_Reinj_1_1 2956 36166 22364 Mix4_TiO2_1_5 2849 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.999718 36.4334 0.999286 33.0647 0.0004559 104.18 0 0 0.999718 36.4334 0.00269506 89.051 0 0 0 0 0.482691 5.0096 0.860187 5.9849 1 T EESRPYTNKVITL CAMK2 0.042 0.0004559 104.18 _LYNSEESRPYpTNK_ LYNSEESRPYT(1)NK LY(-65.94)NS(-64.4)EES(-36.43)RPY(-42.67)T(36.43)NK 11 2 840.86689 -0.16847 1397500 305930 0 0 1091600 0 0 0 3392 1699 1246 1246 5054 5748 48867 29866 Mix4_TiO2_Reinj_1_1 2035 48867 29866 Mix4_TiO2_Reinj_1_1 2035 Q9NYV4-2 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 0.598192 1.72822 0 0 0.598192 1.72822 0.0175064 64.341 1 T GPRRTPTMPQEEA CAMK2 0.042 0.0175064 64.341 _RTPpTM(ox)PQEEAAEK_ RT(0.402)PT(0.598)MPQEEAAEK RT(-1.73)PT(1.73)MPQEEAAEK 4 2 792.3422 -0.069001 45504 0 0 0 45504 0 0 0 3393 1704 4263 4263 1183 1329 11106 6805 Mix4_InSol_TiO2_1 7869 11110 6812 Mix4_TiO2_Reinj_1_1 6836 Q9NZJ4;Q9NZJ4-2 Q9NZJ4 Q9NZJ4 >sp|Q9NZJ4|SACS_HUMAN Sacsin OS=Homo sapiens GN=SACS PE=1 SV=2;>sp|Q9NZJ4-2|SACS_HUMAN Isoform 2 of Sacsin OS=Homo sapiens GN=SACS 0.624359 5.92484 0.302302 -1.11589 0.0578213 55.643 0.219415 0 1.54523 4.2811 0.298458 -1.30323 7.08564E-07 114.96 0.624359 5.92484 0.000862965 84.159 0.0812242 -10.1315 0.00320189 77.457 1 T SAPSTPTSPTEFL CK1 0.081 7.08564E-07 114.96 _DSAPSTPpTSPTEFLTPGLR_ DSAPS(0.16)T(0.014)PT(0.624)S(0.088)PT(0.113)EFLTPGLR DS(-33)APS(-5.92)T(-16.37)PT(5.92)S(-8.52)PT(-7.41)EFLT(-34.81)PGLR 8 2 1027.4775 0.19565 229310 0 0 0 0 0 229310 0 3394 1704 4266 4266 1183 1329 11110 6812 Mix4_TiO2_Reinj_1_1 6836 11110 6812 Mix4_TiO2_Reinj_1_1 6836 Q9NZJ4;Q9NZJ4-2 Q9NZJ4 Q9NZJ4 >sp|Q9NZJ4|SACS_HUMAN Sacsin OS=Homo sapiens GN=SACS PE=1 SV=2;>sp|Q9NZJ4-2|SACS_HUMAN Isoform 2 of Sacsin OS=Homo sapiens GN=SACS 0.402908 1.30323 0.390868 1.11589 0.0578213 55.643 0.136913 -2.0482 1.54523 4.2811 0.402908 1.30323 7.08564E-07 114.96 0.113399 -7.40824 0.000862965 84.159 0.0812242 -10.1315 0.00320189 77.457 1 T STPTSPTEFLTPG FHA2 Rad53p 0.114 7.08564E-07 114.96 _DSAPSTPTSPpTEFLTPGLR_ DSAPSTPT(0.298)S(0.298)PT(0.403)EFLTPGLR DS(-80.32)APS(-50.14)T(-33.86)PT(-1.3)S(-1.3)PT(1.3)EFLT(-47.13)PGLR 11 2 1027.4775 1.0429 0 0 0 0 0 0 0 0 3395 1713 596 596 6519 7459 65855 40344 Mix4_InSol_TiO2_2 3166 65857 40346 Mix4_TiO2_1_3 3287 Q9P0L2;Q9P0L2-3;Q9P0L2-2 Q9P0L2 Q9P0L2 >sp|Q9P0L2|MARK1_HUMAN Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2;>sp|Q9P0L2-3|MARK1_HUMAN Isoform 3 of Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1;>sp|Q9P0L2-2|MARK1_HUMAN Isoform 2 of Serine/threonine-prot 0.181955 0 0.00147062 -28.0656 7.69541E-21 159.43 0 0 4.92883E-06 -52.782 3.69825E-06 107.74 0.181955 0 0.00129194 83.131 0.0402042 -12.6165 1.12409 12.616 1 T SAHSISTATPDRT CK1 0.081 7.69541E-21 159.43 _VPAASPSAHpSISTATPDR_ VPAAS(0.151)PS(0.151)AHS(0.182)IS(0.182)T(0.182)AT(0.151)PDR VPAAS(-0.8)PS(-0.8)AHS(0)IS(0)T(0)AT(-0.8)PDR 13 2 922.93055 0.029916 0 0 0 0 0 0 0 0 3396 1723 667 667 2579 2934 24165 15001 Mix4_TiO2_Reinj_1_5 3769 24165 15001 Mix4_TiO2_Reinj_1_5 3769 Q9P2K8;Q9P2K8-2 Q9P2K8 Q9P2K8 >sp|Q9P2K8|E2AK4_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 4 OS=Homo sapiens GN=EIF2AK4 PE=1 SV=3;>sp|Q9P2K8-2|E2AK4_HUMAN Isoform 2 of Eukaryotic translation initiation factor 2-alpha kinase 4 OS=Homo sapiens GN=EIF2AK4 1 86.5507 0.773126 5.32464 1.50776 5.3246 0 0 1 86.5507 4.05987E-10 123.12 0 0 0 0 1 T RPAGPGTPPPDSG ERK/MAPK;Proline-directed 0.0025 4.05987E-10 123.12 _HERPAGPGpTPPPDSGPLAK_ HERPAGPGT(1)PPPDSGPLAK HERPAGPGT(86.55)PPPDS(-86.55)GPLAK 9 3 654.31407 -0.23481 2390700 40468 0 0 2350200 0 0 0 3397 1730 690 690 6476 7407 65434 40110 Mix4_InSol_TiO2_1 4811 65434 40110 Mix4_InSol_TiO2_1 4811 Q9UBH6;Q9UBH6-2 Q9UBH6 Q9UBH6 >sp|Q9UBH6|XPR1_HUMAN Xenotropic and polytropic retrovirus receptor 1 OS=Homo sapiens GN=XPR1 PE=1 SV=1;>sp|Q9UBH6-2|XPR1_HUMAN Isoform 2 of Xenotropic and polytropic retrovirus receptor 1 OS=Homo sapiens GN=XPR1 1 65.9945 0.999826 37.5999 0.126988 37.6 0.999979 46.8081 0.064621 46.808 0 0 1 65.9945 0.0105745 72.194 0.999964 44.4407 0.067713 45.932 1 T KVLIEDTDDEANT CK2 0.117 0.0105745 72.194 _VLIEDpTDDEANT_ VLIEDT(1)DDEANT VLIEDT(65.99)DDEANT(-65.99) 6 2 707.7847 -0.26289 1014400 11.896 125020 0 0 623710 0 157060 108620 3398 1739 221 221 1954 2212;2213 17894 10699 Mix4_TiO2_1_4 5456 17894 10699 Mix4_TiO2_1_4 5456 Q9UGJ0;Q9UGJ0-3 Q9UGJ0 Q9UGJ0 >sp|Q9UGJ0|AAKG2_HUMAN 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 PE=1 SV=1;>sp|Q9UGJ0-3|AAKG2_HUMAN Isoform C of 5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens GN=PRKAG2 0.765029 5.28776 0.765029 5.28776 1.22712E-11 128.11 0.212691 -5.43886 0.173278 50.841 0.218058 -6.00456 0.163771 51.404 0.402691 -0.509909 0.943844 31.458 1 T PPLASPTHYAPSK FHA KAPP 0.155 1.22712E-11 128.11 _FCPSSFQSPTRPPLASPpTHYAPSK_ FCPSSFQSPTRPPLAS(0.226)PT(0.765)HY(0.005)APS(0.003)K FCPS(-92.73)S(-72.57)FQS(-33.76)PT(-42.18)RPPLAS(-5.29)PT(5.29)HY(-21.91)APS(-23.71)K 18 3 914.09116 -0.46673 334570 334570 0 0 0 0 0 0 3399 1762 562 562 4265 4854 40549 24976 Mix4_TiO2_1_4 8077 40549 24976 Mix4_TiO2_1_4 8077 Q9UJX2;Q9UJX2-3 Q9UJX2 Q9UJX2 >sp|Q9UJX2|CDC23_HUMAN Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 PE=1 SV=3;>sp|Q9UJX2-3|CDC23_HUMAN Isoform 3 of Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 0.651545 5.72828 0.651545 5.72828 2.34013E-18 147.34 0.333314 0 0.014721 71.124 1 T LRNQGETPTTEVP Proline-directed 0.05 2.34013E-18 147.34 _NQGEpTPTTEVPAPFFLPASLSANNTPTR_ NQGET(0.652)PT(0.174)T(0.174)EVPAPFFLPASLSANNTPTR NQGET(5.73)PT(-5.73)T(-5.73)EVPAPFFLPAS(-88.17)LS(-110.68)ANNT(-142.01)PT(-141.73)R 5 3 1013.1483 -0.81463 149080 0.038986 149080 0 0 0 0 0 0 3400 1762 564 564 4265 4854 40550 24977 Mix4_TiO2_Reinj_1_3 8865 40549 24976 Mix4_TiO2_1_4 8077 Q9UJX2;Q9UJX2-3 Q9UJX2 Q9UJX2 >sp|Q9UJX2|CDC23_HUMAN Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 PE=1 SV=3;>sp|Q9UJX2-3|CDC23_HUMAN Isoform 3 of Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 0.413792 0 0.333333 0 2.34013E-18 147.34 0.413792 0 0.014721 71.124 1 T NQGETPTTEVPAP 2.34013E-18 147.34 _NQGETPpTTEVPAPFFLPASLSANNTPTR_ NQGET(0.172)PT(0.414)T(0.414)EVPAPFFLPASLSANNTPTR NQGET(-3.82)PT(0)T(0)EVPAPFFLPAS(-29.95)LS(-35.05)ANNT(-59.27)PT(-65.68)R 7 3 1013.1483 -0.31066 0 0 0 0 0 0 0 0 0 3401 1762 565 565 4265 4854 40550 24977 Mix4_TiO2_Reinj_1_3 8865 40549 24976 Mix4_TiO2_1_4 8077 Q9UJX2;Q9UJX2-3 Q9UJX2 Q9UJX2 >sp|Q9UJX2|CDC23_HUMAN Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 PE=1 SV=3;>sp|Q9UJX2-3|CDC23_HUMAN Isoform 3 of Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 0.413792 0 0.333333 0 2.34013E-18 147.34 0.413792 0 0.014721 71.124 1 T QGETPTTEVPAPF 2.34013E-18 147.34 _NQGETPpTTEVPAPFFLPASLSANNTPTR_ NQGET(0.172)PT(0.414)T(0.414)EVPAPFFLPASLSANNTPTR NQGET(-3.82)PT(0)T(0)EVPAPFFLPAS(-29.95)LS(-35.05)ANNT(-59.27)PT(-65.68)R 8 3 1013.1483 -0.31066 0 0 0 0 0 0 0 0 0 3402 1762 596 596 5069;6604 5763;5764;7559 67008 41128 Mix4_TiO2_Reinj_1_3 6928 49020 29959 Mix4_TiO2_Reinj_1_3 6983 Q9UJX2;Q9UJX2-3 Q9UJX2 Q9UJX2 >sp|Q9UJX2|CDC23_HUMAN Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 PE=1 SV=3;>sp|Q9UJX2-3|CDC23_HUMAN Isoform 3 of Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 0.998905 29.7472 0.995171 24.4314 0.00102561 101.08 0.0249625 -15.6891 0.460969 15.689 0.998905 29.7472 0.000767824 105.96 1.23883E-05 -49.0517 0.0566967 49.052 0.750559 9.55537 0.0041987 87.847 1 T LNLSSVTP_____ CK1;Proline-directed 0.05 0.000767824 105.96 _VSPLNLSSVpTP_ VSPLNLSS(0.001)VT(0.999)P VS(-48.2)PLNLS(-46.78)S(-29.75)VT(29.75)P 10 2 597.29431 -0.090163 195010 19238 0 0 153340 0 0 22434 3403 1766 327 327 411 469 3895 2330 Mix4_TiO2_1_4 3473 3895 2330 Mix4_TiO2_1_4 3473 Q9UJZ1 Q9UJZ1 Q9UJZ1 >sp|Q9UJZ1|STML2_HUMAN Stomatin-like protein 2 OS=Homo sapiens GN=STOML2 PE=1 SV=1 0.957511 14.4689 0.957511 14.4689 0.020776 64.084 0 0 0.702981 4.54121 0.0477737 56.788 0 0 0 0 0 0 1 T KAPVPGTPDSLSS ERK/MAPK;FHA KAPP;Proline-directed 0.0025 0.020776 64.084 _APVPGpTPDSLSSGSSR_ APVPGT(0.958)PDS(0.034)LS(0.007)S(0.001)GSSR APVPGT(14.47)PDS(-14.47)LS(-21.51)S(-28.41)GS(-41.77)S(-41.77)R 6 2 797.85907 1.0697 246010 82303 0 0 163710 0 0 0 3404 1771 1244 1244 5849 6669 57677 35096 Mix4_InSol_Tio2_Reinj_1 6957 57679 35098 Mix4_TiO2_Reinj_1_1 6015 Q9UKA4 Q9UKA4 Q9UKA4 >sp|Q9UKA4|AKA11_HUMAN A-kinase anchor protein 11 OS=Homo sapiens GN=AKAP11 PE=1 SV=1 0.41449 1.03937 0.0061113 -22.0778 0.0337631 58.647 0 0 6.41617E-05 -41.4942 5.26E-05 107.38 0 0 0.41449 1.03937 0.513254 25.513 1 T QRSVSPTFLNPSD 5.26E-05 107.38 _SVSPpTFLNPSDENLK_ S(0.258)VS(0.326)PT(0.414)FLNPS(0.001)DENLK S(-2.06)VS(-1.04)PT(1.04)FLNPS(-25.51)DENLK 5 2 864.39802 0.26364 0 0 0 0 0 0 0 0 3405 1772 984 984 6666 7631 67583 41496 Mix4_TiO2_1_5 8422 67583 41496 Mix4_TiO2_1_5 8422 Q9UKE5;Q9UKE5-4;Q9UKE5-2;Q9UKE5-6;Q9UKE5-3;Q9UKE5-7;Q9UKE5-5;Q9UKE5-8 Q9UKE5 Q9UKE5 >sp|Q9UKE5|TNIK_HUMAN TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1;>sp|Q9UKE5-4|TNIK_HUMAN Isoform 4 of TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK;>sp|Q9UKE5-2|TNIK_HUMAN Isoform 2 of TRAF2 and NCK-intera 0.429309 1.49661 0.429309 1.49661 3.9984E-12 125.03 0 0 0 0 1 T DPRVYQTSPTDED 14-3-3 binding 0.0001533 3.9984E-12 125.03 _VYQpTSPTDEDEEDEESSAAALFTSELLR_ VY(0.048)QT(0.429)S(0.304)PT(0.217)DEDEEDEES(0.001)SAAALFTSELLR VY(-9.48)QT(1.5)S(-1.5)PT(-2.96)DEDEEDEES(-25.93)S(-43.8)AAALFT(-99.5)S(-109.5)ELLR 4 3 1071.4608 0.34094 0 0 0 0 0 0 0 0 0 3406 1773 286 286 6192 7071;7073 61302 37129 Mix4_TiO2_1_4 5181 61302 37129 Mix4_TiO2_1_4 5181 Q9UKM9;Q9UKM9-2 Q9UKM9 Q9UKM9 >sp|Q9UKM9|RALY_HUMAN RNA-binding protein Raly OS=Homo sapiens GN=RALY PE=1 SV=1;>sp|Q9UKM9-2|RALY_HUMAN Isoform 1 of RNA-binding protein Raly OS=Homo sapiens GN=RALY 0.59845 1.7339 0.59845 1.7339 7.82364E-13 129.47 0.497974 0 0.0479635 66.267 0.394653 0.425943 1.78808 24.797 0 0 1 T DEEGLLTHSEEEL CK2 0.117 7.82364E-13 129.47 _TRDDGDEEGLLpTHSEEELEHSQDTDADDGALQ_ TRDDGDEEGLLT(0.598)HS(0.401)EEELEHSQDTDADDGALQ T(-71.53)RDDGDEEGLLT(1.73)HS(-1.73)EEELEHS(-38.19)QDT(-51.76)DADDGALQ 12 3 1203.1536 -0.12984 4082500 0.72412 4082500 0 0 0 0 0 0 3407 1773 298 298 6192 7071;7073 61305 37132 Mix4_TiO2_Reinj_1_4 6649 61302 37129 Mix4_TiO2_1_4 5181 Q9UKM9;Q9UKM9-2 Q9UKM9 Q9UKM9 >sp|Q9UKM9|RALY_HUMAN RNA-binding protein Raly OS=Homo sapiens GN=RALY PE=1 SV=1;>sp|Q9UKM9-2|RALY_HUMAN Isoform 1 of RNA-binding protein Raly OS=Homo sapiens GN=RALY 0.95165 12.9511 0.961647 15.5066 1.53762 31.007 0.95165 12.9511 0.00025746 86.522 0.103092 -5.82991 1.78808 24.797 0 0 1 T LEHSQDTDADDGA CK1;CK2;FHA1 Rad53p 0.059 7.82364E-13 129.47 _TRDDGDEEGLLTHSEEELEHSQDpTDADDGALQ_ TRDDGDEEGLLTHSEEELEHS(0.048)QDT(0.952)DADDGALQ T(-74.02)RDDGDEEGLLT(-44.83)HS(-40.61)EEELEHS(-12.95)QDT(12.95)DADDGALQ 24 3 1203.1536 0.48712 884640 0.15691 0 0 0 884640 0 0 0 3408 1780 931 931 5180 5897 50152 30654 Mix4_TiO2_1_5 2402 50152 30654 Mix4_TiO2_1_5 2402 Q9ULE0 Q9ULE0 Q9ULE0 >sp|Q9ULE0|WWC3_HUMAN Protein WWC3 OS=Homo sapiens GN=WWC3 PE=2 SV=3 0.332342 0 0.332342 0 0.027654 53.4 0 0 1 T SDSDSSTLPRKSP 0.027654 53.4 _SDSDpSSTLPR_ SDS(0.003)DS(0.332)S(0.332)T(0.332)LPR S(-48.73)DS(-20.49)DS(0)S(0)T(0)LPR 7 2 572.72953 0.027209 0 0 0 0 0 0 0 0 3409 1785 585 585 4439 5049 42233 25999 Mix4_TiO2_Reinj_1_5 2784 42232 25998 Mix4_TiO2_1_5 2183 Q9ULV3;Q9ULV3-2;Q9ULV3-4;Q9ULV3-3 Q9ULV3 Q9ULV3 >sp|Q9ULV3|CIZ1_HUMAN Cip1-interacting zinc finger protein OS=Homo sapiens GN=CIZ1 PE=1 SV=2;>sp|Q9ULV3-2|CIZ1_HUMAN Isoform NP94B of Cip1-interacting zinc finger protein OS=Homo sapiens GN=CIZ1;>sp|Q9ULV3-4|CIZ1_HUMAN Isoform 4 of Cip1-interacting zinc fi 0.678266 6.33292 0.483603 1.04851 9.89549E-06 99.344 0 0 0.678266 6.33292 0.0146704 68.704 1 T TPAATSTPSKQAL CDK1;CDK2;Polo box;Proline-directed 0.00405 9.89549E-06 99.344 _PSDSVSSTPAATSpTPSK_ PSDSVSST(0.001)PAAT(0.004)S(0.158)T(0.678)PS(0.158)K PS(-68.7)DS(-68.7)VS(-54)S(-32.96)T(-26.92)PAAT(-21.87)S(-6.33)T(6.33)PS(-6.33)K 14 2 850.37475 0.13627 97270 0 0 0 97270 0 0 0 3410 1794 72 72 563 645 5323 3214 Mix4_TiO2_Reinj_1_3 1953 5323 3214 Mix4_TiO2_Reinj_1_3 1953 Q9UNF1;Q9UNF1-2 Q9UNF1 Q9UNF1 >sp|Q9UNF1|MAGD2_HUMAN Melanoma-associated antigen D2 OS=Homo sapiens GN=MAGED2 PE=1 SV=2;>sp|Q9UNF1-2|MAGD2_HUMAN Isoform 2 of Melanoma-associated antigen D2 OS=Homo sapiens GN=MAGED2 0.978072 16.4937 0.3248 -3.17775 0.0855696 40.125 0 0 0.978072 16.4937 0.00326082 78.999 0 0 0.353116 0.381206 0.736631 0.38121 1 T ATEVSKTPEAREA FHA KAPP;Proline-directed 0.05 0.00326082 78.999 _ATEVSKpTPEAR_ ATEVS(0.022)KT(0.978)PEAR AT(-70.43)EVS(-16.49)KT(16.49)PEAR 7 2 634.79775 -0.037534 114470 0 0 0 114470 0 0 0 3411 1801 725 725 2199 2491 20174 12405 Mix4_TiO2_1_5 7428 20174 12405 Mix4_TiO2_1_5 7428 Q9UPN7 Q9UPN7 Q9UPN7 >sp|Q9UPN7|PP6R1_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens GN=PPP6R1 PE=1 SV=5 0.484914 0 0.484914 0 0.000681553 90.847 0.388341 -1.2881 0.113989 69.088 1 T VPTDAPTSPRVSG 0.000681553 90.847 _GGATPLSYPSPGPQPPGPSWTATFDPVPTDAPpTSPR_ GGATPLSYPSPGPQPPGPSWTATFDPVPT(0.03)DAPT(0.485)S(0.485)PR GGAT(-84.05)PLS(-81.72)Y(-77.21)PS(-71.62)PGPQPPGPS(-54.61)WT(-49.69)AT(-38.13)FDPVPT(-12.07)DAPT(0)S(0)PR 33 3 1228.5733 0.88844 0 0 0 0 0 0 0 0 3412 1803 1509 1509 2281 2579 21013 12871 Mix4_TiO2_1_5 7333 21015 12873 Mix4_TiO2_Reinj_1_5 8034 Q9UPQ9;Q9UPQ9-1;Q9UPQ9-2 Q9UPQ9 Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B PE=1 SV=4;>sp|Q9UPQ9-1|TNR6B_HUMAN Isoform 2 of Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens GN=TNRC6B;>sp|Q9UPQ9-2|TNR6B_HUMAN Isoform 3 of 0.685997 7.12198 0.685997 7.12198 6.56826E-07 105.84 0 0 0.0806953 -8.27147 1.22972E-11 125.2 0 0 0 0 1 T GSVLGGTATSPIV FHA KAPP;NEK6 0.076 1.22972E-11 125.2 _GIQNIDPESDPYVTPGSVLGGpTATSPIVDTDHQLLR_ GIQNIDPESDPYVTPGS(0.048)VLGGT(0.686)AT(0.133)S(0.133)PIVDTDHQLLR GIQNIDPES(-62.53)DPY(-46.9)VT(-36.78)PGS(-11.59)VLGGT(7.12)AT(-7.12)S(-7.12)PIVDT(-37.28)DHQLLR 22 3 1281.621 0.05658 444840 444840 0 0 0 0 0 0 3413 1805 2559 2559 6032 6880 59615 36182 Mix4_TiO2_Reinj_1_6 7532 59598 36161 Mix4_TiO2_1_1 7592 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.861051 7.92198 0.403229 -1.70255 2.34538E-99 315.24 0.230217 -4.02361 8.79733E-26 182.78 0.861051 7.92198 1.86957E-58 255.73 1 T GKTFQRTISAQDT FHA KAPP 0.155 2.34538E-99 315.24 _pTISAQDTLAYATALLNEK_ T(0.861)IS(0.139)AQDTLAYATALLNEK T(7.92)IS(-7.92)AQDT(-50.11)LAY(-95.52)AT(-106.36)ALLNEK 1 2 1001.9903 0.39814 5064200 0 0 0 5064200 0 0 0 3414 1805 2565 2565 6032 6880 59606 36172 Mix4_TiO2_Reinj_1_1 8443 59598 36161 Mix4_TiO2_1_1 7592 Q9UPU5 Q9UPU5 Q9UPU5 >sp|Q9UPU5|UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens GN=USP24 PE=1 SV=3 0.992967 21.5542 0.956823 13.9201 2.34538E-99 315.24 0.581433 4.02361 8.79733E-26 182.78 0.992967 21.5542 1.86957E-58 255.73 1 T TISAQDTLAYATA 2.34538E-99 315.24 _TISAQDpTLAYATALLNEK_ TIS(0.007)AQDT(0.993)LAYATALLNEK T(-40.45)IS(-21.55)AQDT(21.55)LAY(-62.21)AT(-136.99)ALLNEK 7 3 668.32928 -0.022511 2541400 411490 26970 0 2103000 0 0 0 3415 1809 157 157 5395 6140 52532 32118 Mix4_TiO2_1_3 3402 52532 32118 Mix4_TiO2_1_3 3402 Q9UPZ9;Q9UPZ9-2 Q9UPZ9 Q9UPZ9 >sp|Q9UPZ9|ICK_HUMAN Serine/threonine-protein kinase ICK OS=Homo sapiens GN=ICK PE=1 SV=1;>sp|Q9UPZ9-2|ICK_HUMAN Isoform 2 of Serine/threonine-protein kinase ICK OS=Homo sapiens GN=ICK 0.994865 22.8737 0.994865 22.8737 0.00746205 77.816 0.993378 21.7697 0.00807324 76.712 2 T RSKPPYTDYVSTR 0.00746205 77.816 _SKPPYpTDpYVSTR_ SKPPY(0.005)T(0.995)DY(1)VSTR S(-73.99)KPPY(-22.87)T(22.87)DY(39.46)VS(-44.03)T(-64.51)R 6 2 787.3204 0.15983 1281100 270590 0 0 1010500 0 0 0 3416 1810 2583 2583 5063 5757 48958 29909 Mix4_TiO2_Reinj_1_5 2668 48954 29905 Mix4_InSol_TiO2_2 1985 Q9UQ35;Q9UQ35-2 Q9UQ35 Q9UQ35 >sp|Q9UQ35|SRRM2_HUMAN Serine/arginine repetitive matrix protein 2 OS=Homo sapiens GN=SRRM2 PE=1 SV=2;>sp|Q9UQ35-2|SRRM2_HUMAN Isoform 2 of Serine/arginine repetitive matrix protein 2 OS=Homo sapiens GN=SRRM2 0.5 0 0 0 0 0 0.5 0 0.170446 32.235 0.0105859 -19.7065 0.01314 58.205 0.48691 -0.227442 0.748296 2.1207 1 T KRVPSPTPAPKEA Proline-directed 0.05 0.01314 58.205 _RVPpSPTPAPK_ RVPS(0.5)PT(0.5)PAPK RVPS(0)PT(0)PAPK 6 2 565.29191 0.14832 40415 0 0 0 40415 0 0 0 3417 1819 4 4 678 779 6484 3853 Mix4_InSol_TiO2_1 5131 6484 3853 Mix4_InSol_TiO2_1 5131 Q9Y277-2;Q9Y277 Q9Y277-2 Q9Y277-2 >sp|Q9Y277-2|VDAC3_HUMAN Isoform 2 of Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens GN=VDAC3;>sp|Q9Y277|VDAC3_HUMAN Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens GN=VDAC3 PE=1 SV=1 0.989463 20.1518 0.964051 14.8823 0.00768729 68.109 0.971342 17.1972 0.00391952 77.378 0.989463 20.1518 0.00149049 100.44 0.887084 8.96291 0.0068144 70.256 1 T ___MCNTPTYCDL Proline-directed 0.05 0.00149049 100.44 _(ac)CNpTPTYCDLGK_ CNT(0.989)PT(0.01)Y(0.001)CDLGK CNT(20.15)PT(-20.15)Y(-30.03)CDLGK 3 2 725.77256 -0.38485 111210 18744 0 0 23789 0 34884 33794 3418 1825 283 283 4604 5227 43681 26782 Mix4_TiO2_Reinj_1_4 8019 43681 26782 Mix4_TiO2_Reinj_1_4 8019 Q9Y2H1 Q9Y2H1 Q9Y2H1 >sp|Q9Y2H1|ST38L_HUMAN Serine/threonine-protein kinase 38-like OS=Homo sapiens GN=STK38L PE=1 SV=3 0.452342 0 0.399243 0 1.47848 24.887 0.452342 0 1.45212E-11 122.71 1 T RQLAYSTVGTPDY 1.45212E-11 122.71 _QLAYpSTVGTPDYIAPEVFM(ox)QTGYNK_ QLAY(0.081)S(0.452)T(0.452)VGT(0.015)PDYIAPEVFMQTGYNK QLAY(-7.49)S(0)T(0)VGT(-14.88)PDY(-43.33)IAPEVFMQT(-122.71)GY(-122.71)NK 6 3 963.77327 0.78442 0 0 0 0 0 0 0 0 3419 1826 75 75 161 188 1757 1202 Mix4_TiO2_1_1 5119 1753 1198 Mix4_InSol_TiO2_1 6725 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.65323 2.91136 0.65323 2.91136 0.000281304 90.423 0 0 0.54824 0.929276 1.74909E-05 98.33 0.565276 1.14723 2.79726E-11 122.58 0.630322 2.66069 0.00027552 90.596 1 T PLSGSWTSPQLPS 2.79726E-11 122.58 _AEGGQGEQQPLSGSWpTSPQLPSR_ AEGGQGEQQPLS(0.004)GS(0.002)WT(0.653)S(0.334)PQLPS(0.006)R AEGGQGEQQPLS(-22.22)GS(-24.44)WT(2.91)S(-2.91)PQLPS(-20.12)R 16 2 1239.0583 -0.15423 733040 0.456 137200 0 0 359420 0 136790 99625 3420 1826 477 477 911;1960 1028;2219 8755 5347 Mix4_TiO2_2_1 3933 17953 10730 Mix4_TiO2_Reinj_1_1 5295 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.564482 1.12666 0.5 0 5.42155E-12 120.63 0.564482 1.12666 0.449401 48.83 0.5 0 4.04696E-35 188.12 0 0 1 T KFDDSDTEQIAEE FHA2 Rad53p 0.114 4.04696E-35 188.12 _DIKFDDSDpTEQIAEEGDDNLANSASPSK_ DIKFDDS(0.435)DT(0.564)EQIAEEGDDNLANSASPSK DIKFDDS(-1.13)DT(1.13)EQIAEEGDDNLANS(-48.83)AS(-48.83)PS(-48.83)K 9 3 1031.1015 0.10892 1166300 224030 25661 0 916650 0 0 0 3421 1826 22 22 5593 6375 54729 33522 Mix4_TiO2_Reinj_1_5 6265 54729 33522 Mix4_TiO2_Reinj_1_5 6265 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.379515 0.889437 0 0 0.219035 0 0.0778497 56.7 0.379515 0.889437 0.000523438 81.246 0 0 0 0 1 T DLPRSPTSPSHLT 14-3-3 binding;CAMK2;CHK1;CHK1/2;FHA KAPP;PKD 0.0001701 0.000523438 81.246 _SPpTSPSHLTHFKPLTPDQDEPPFK_ S(0.309)PT(0.38)S(0.171)PS(0.136)HLT(0.004)HFKPLTPDQDEPPFK S(-0.89)PT(0.89)S(-3.46)PS(-4.46)HLT(-19.53)HFKPLT(-59.55)PDQDEPPFK 3 3 928.44073 0.79668 0 0 0 0 0 0 0 0 3422 1826 34 34 5593 6375 54728 33521 Mix4_TiO2_Reinj_1_1 5706 54729 33522 Mix4_TiO2_Reinj_1_5 6265 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.324636 0.284546 0 0 0.054795 -6.01773 0.0778497 56.7 0.324636 0.284546 0.000523438 81.246 0 0 0 0 1 T THFKPLTPDQDEP ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.000523438 81.246 _SPTSPSHLTHFKPLpTPDQDEPPFK_ S(0.304)PT(0.084)S(0.084)PS(0.144)HLT(0.06)HFKPLT(0.325)PDQDEPPFK S(-0.28)PT(-5.87)S(-5.87)PS(-3.54)HLT(-7.36)HFKPLT(0.28)PDQDEPPFK 15 4 696.58237 -0.14849 0 0 0 0 0 0 0 0 3423 1826 90 90 6186;6187 7063;7064 61262 37109 Mix4_InSol_Tio2_Reinj_1 2854 61251 37105 Mix4_TiO2_Reinj_1_1 2575 Q9Y2I7 Q9Y2I7 Q9Y2I7 >sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=3 0.691195 4.90102 0.0339886 -13.7769 0.0593573 45.86 0 0 0.0626111 -8.11964 0.00407511 76.995 0.310121 -3.33892 0.135108 36.918 0.691195 4.90102 0.0249392 58.043 1 T QSVRSPTPYKKQL CAMK2;CDK1;CDK2;Proline-directed 0.0057 0.00407511 76.995 _TQSVRSPpTPYKK_ T(0.004)QS(0.224)VRS(0.081)PT(0.691)PYKK T(-22.37)QS(-4.9)VRS(-9.3)PT(4.9)PY(-58.04)KK 8 2 736.36887 -0.2227 682170 0 0 0 0 0 0 682170 3424 1827 558 558 1228;1229 1382;1383 11516 7044 Mix4_TiO2_Reinj_1_5 5913 11513 7042 Mix4_TiO2_1_5 5597 Q9Y2K2;Q9Y2K2-3 Q9Y2K2 Q9Y2K2 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3;>sp|Q9Y2K2-3|SIK3_HUMAN Isoform 3 of Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 0.968948 14.943 0.00358049 -24.445 0.0190485 65.566 0.968948 14.943 0.0618639 54.828 1 T NTLHLPTERFSPV 0.0190485 65.566 _DSNTLHLPpTERFSPVRR_ DSNTLHLPT(0.969)ERFS(0.031)PVRR DS(-54.83)NT(-54.83)LHLPT(14.94)ERFS(-14.94)PVRR 9 3 702.34778 -0.16933 423800 0 0 0 423800 0 0 0 3425 1827 163 163 6303 7203 63052 38402 Mix4_TiO2_Reinj_1_3 7855 63051 38401 Mix4_TiO2_1_5 6909 Q9Y2K2;Q9Y2K2-3 Q9Y2K2 Q9Y2K2 >sp|Q9Y2K2|SIK3_HUMAN Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 PE=1 SV=3;>sp|Q9Y2K2-3|SIK3_HUMAN Isoform 3 of Serine/threonine-protein kinase SIK3 OS=Homo sapiens GN=SIK3 1 80.8427 0.999998 56.4708 8.2182E-15 156.56 1 80.8427 8.98648E-13 146.48 1 T PGQLLKTWCGSPP NEK6 0.076 8.2182E-15 156.56 _pTWCGSPPYAAPELFEGK_ T(1)WCGSPPYAAPELFEGK T(80.84)WCGS(-80.84)PPY(-131.79)AAPELFEGK 1 2 995.42626 -0.17654 656830 169240 0 0 487590 0 0 0 3426 1831 337 337 4888;5023 5559;5713;5714 48499 29667 Mix4_InSol_Tio2_Reinj_2 5394 48511 29668 Mix4_TiO2_Reinj_1_3 5856 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.791107 8.86995 0.69337 5.71714 0.172988 42.84 0.151236 -7.43531 3.9676E-11 127.66 0.234013 -1.82764 1.78587 4.1683 0.791107 8.86995 1.44972 13.489 1 T SDIDNPTLTVMDI 3.9676E-11 127.66 _RRGSDIDNPpTLTVMDISPPSR_ RRGS(0.103)DIDNPT(0.791)LT(0.035)VMDIS(0.035)PPS(0.035)R RRGS(-8.87)DIDNPT(8.87)LT(-13.49)VMDIS(-13.49)PPS(-13.49)R 10 3 803.0527 0.21003 184480 145180 0 0 0 0 0 39301 3427 1831 310 310 5597 6379 54748 33530 Mix4_TiO2_Reinj_1_3 7324 54748 33530 Mix4_TiO2_Reinj_1_3 7324 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.420255 0 0.237198 -1.84304 0.000122289 90.986 0.420255 0 5.34622E-05 95.428 0 0 0.0941786 -5.42277 1.06375 37.019 1 T TDHSLSTSSGSSI CK1 0.081 5.34622E-05 95.428 _SPVSFSPTDHSLSpTSSGSSIFTPEYDDSR_ SPVS(0.001)FS(0.004)PT(0.017)DHS(0.02)LS(0.091)T(0.42)S(0.42)S(0.02)GS(0.005)S(0.001)IFTPEYDDSR S(-34.02)PVS(-27.29)FS(-20.33)PT(-13.98)DHS(-13.15)LS(-6.64)T(0)S(0)S(-13.15)GS(-19.53)S(-25.01)IFT(-60.51)PEY(-75.76)DDS(-90.12)R 14 3 1057.454 0.40372 0 0 0 0 0 0 0 0 3428 1835 283 283 222 256 2214 1440 Mix4_TiO2_1_2 3211 2215 1441 Mix4_TiO2_Reinj_1_2 3862 Q9Y320;Q9Y320-2 Q9Y320 Q9Y320 >sp|Q9Y320|TMX2_HUMAN Thioredoxin-related transmembrane protein 2 OS=Homo sapiens GN=TMX2 PE=1 SV=1;>sp|Q9Y320-2|TMX2_HUMAN Isoform 2 of Thioredoxin-related transmembrane protein 2 OS=Homo sapiens GN=TMX2 0.41585 0.977356 0.41585 0.977356 1.79175 17.188 0.167846 -5.8186 5.47823E-07 100.73 1 T EQPVASTPTTVSD Polo box;Proline-directed 0.00405 5.47823E-07 100.73 _AGDNIPEEQPVASpTPTTVSDGENKK_ AGDNIPEEQPVAS(0.084)T(0.416)PT(0.084)T(0.084)VS(0.332)DGENKK AGDNIPEEQPVAS(-6.94)T(0.98)PT(-6.94)T(-6.94)VS(-0.98)DGENKK 14 3 888.73939 0.061466 0 0 0 0 0 0 0 0 0 3429 1840 267 267 4961 5642 47878 29280 Mix4_InSol_Tio2_Reinj_1 4601 47879 29281 Mix4_TiO2_Reinj_1_2 3631 Q9Y385 Q9Y385 Q9Y385 >sp|Q9Y385|UB2J1_HUMAN Ubiquitin-conjugating enzyme E2 J1 OS=Homo sapiens GN=UBE2J1 PE=1 SV=2 0.440908 0 0 0 0.104903 -8.76945 6.10288E-05 105.64 0.299966 -3.42495 0.0764741 50.982 0.440908 0 0.0313254 59.109 1 T SQRRLSTSPDVIQ CAMK2;CK2;FHA1 Rad53p 0.042 6.10288E-05 105.64 _RLSpTSPDVIQGHQPR_ RLS(0.118)T(0.441)S(0.441)PDVIQGHQPR RLS(-5.72)T(0)S(0)PDVIQGHQPR 4 3 590.95974 -0.0159 0 0 0 0 0 0 0 0 3430 1852 592 592 4035 4597 38159 23429 Mix4_TiO2_Reinj_1_3 6130 38156 23425 Mix4_TiO2_1_3 5419 Q9Y3Z3;Q9Y3Z3-2 Q9Y3Z3 Q9Y3Z3 >sp|Q9Y3Z3|SAMH1_HUMAN SAM domain and HD domain-containing protein 1 OS=Homo sapiens GN=SAMHD1 PE=1 SV=2;>sp|Q9Y3Z3-2|SAMH1_HUMAN Isoform 2 of SAM domain and HD domain-containing protein 1 OS=Homo sapiens GN=SAMHD1 1 172.631 1 190.988 4.87159E-27 190.99 0 0 1 172.631 2.53948E-22 172.63 1 106.291 1.18323E-06 106.29 1 76.6957 0.00320655 76.696 1 T VIAPLITPQKKEW CDK1;CDK2;Proline-directed 0.0057 4.87159E-27 190.99 _NFTKPQDGDVIAPLIpTPQKK_ NFTKPQDGDVIAPLIT(1)PQKK NFT(-172.63)KPQDGDVIAPLIT(172.63)PQKK 16 3 764.06628 0.058036 4958400 1108800 0 0 3241000 0 363340 245270 3431 1857 1622 1622 2001 2265;2266 18184 10843 Mix4_TiO2_1_1 6564 18185 10844 Mix4_TiO2_Reinj_1_1 7336 Q9Y4A5;Q9Y4A5-2 Q9Y4A5 Q9Y4A5 >sp|Q9Y4A5|TRRAP_HUMAN Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP PE=1 SV=3;>sp|Q9Y4A5-2|TRRAP_HUMAN Isoform 2 of Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP 0.94288 16.4195 0.94288 16.4195 0.00266775 77.592 0 0 0.000737771 -26.4352 2.40631E-07 110.48 0 0 1 T LPGGAQTAVRPGS 2.40631E-07 110.48 _FITLLLPGGAQpTAVRPGSPSTSTM(ox)R_ FITLLLPGGAQT(0.943)AVRPGS(0.022)PS(0.009)T(0.009)S(0.009)T(0.01)MR FIT(-54.37)LLLPGGAQT(16.42)AVRPGS(-16.42)PS(-20.38)T(-20.38)S(-20.38)T(-19.88)MR 12 3 885.45057 0.10042 325580 325580 0 0 0 0 0 0 3432 1857 1631 1631 2001 2265;2266 18189 10846 Mix4_TiO2_Reinj_1_1 7524 18185 10844 Mix4_TiO2_Reinj_1_1 7336 Q9Y4A5;Q9Y4A5-2 Q9Y4A5 Q9Y4A5 >sp|Q9Y4A5|TRRAP_HUMAN Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP PE=1 SV=3;>sp|Q9Y4A5-2|TRRAP_HUMAN Isoform 2 of Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP 0.241022 0 0.0813072 -8.17929 0.00266775 77.592 0 0 0.241022 0 2.40631E-07 110.48 0 0 1 T RPGSPSTSTMRLD CK1 0.081 2.40631E-07 110.48 _FITLLLPGGAQTAVRPGSPpSTSTMR_ FITLLLPGGAQT(0.001)AVRPGS(0.035)PS(0.241)T(0.241)S(0.241)T(0.241)MR FIT(-67.24)LLLPGGAQT(-25.59)AVRPGS(-8.35)PS(0)T(0)S(0)T(0)MR 21 3 880.11893 -0.77563 0 0 0 0 0 0 0 0 3433 1857 1633 1633 2001 2265;2266 18189 10846 Mix4_TiO2_Reinj_1_1 7524 18185 10844 Mix4_TiO2_Reinj_1_1 7336 Q9Y4A5;Q9Y4A5-2 Q9Y4A5 Q9Y4A5 >sp|Q9Y4A5|TRRAP_HUMAN Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP PE=1 SV=3;>sp|Q9Y4A5-2|TRRAP_HUMAN Isoform 2 of Transformation/transcription domain-associated protein OS=Homo sapiens GN=TRRAP 0.241022 0 0.0813072 -8.17929 0.00266775 77.592 0 0 0.241022 0 2.40631E-07 110.48 0 0 1 T GSPSTSTMRLDLQ CK1;FHA2 Rad53p 0.081 2.40631E-07 110.48 _FITLLLPGGAQTAVRPGSPpSTSTMR_ FITLLLPGGAQT(0.001)AVRPGS(0.035)PS(0.241)T(0.241)S(0.241)T(0.241)MR FIT(-67.24)LLLPGGAQT(-25.59)AVRPGS(-8.35)PS(0)T(0)S(0)T(0)MR 23 3 880.11893 -0.77563 0 0 0 0 0 0 0 0 3434 1862 24 24 3431 3875 32205 19899 Mix4_InSol_Tio2_Reinj_1 5362 32207 19901 Mix4_TiO2_Reinj_1_5 5126 Q9Y4F1-2;Q9Y4F1 Q9Y4F1-2 Q9Y4F1-2 >sp|Q9Y4F1-2|FARP1_HUMAN Isoform 2 of FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1;>sp|Q9Y4F1|FARP1_HUMAN FERM, RhoGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens GN=FARP1 PE=1 SV=1 0.981736 17.3045 0.107912 -9.17269 0.019323 64.455 0 0 0.325322 -3.16702 0.010377 72.927 0.514511 0.258722 0.0639365 50.697 0.981736 17.3045 0.0148909 68.652 1 T ENSGISTLERGQK 0.010377 72.927 _LGAPENSGISpTLER_ LGAPENSGIS(0.018)T(0.982)LER LGAPENS(-55.62)GIS(-17.3)T(17.3)LER 11 2 762.3587 0.61196 102530 0 0 0 0 0 18313 84217 3435 1863 1675 1675 6243 7133 61979 37547 Mix4_TiO2_Reinj_1_5 8362 61976 37544 Mix4_TiO2_Reinj_1_1 7958 Q9Y4I1-3;Q9Y4I1;Q9Y4I1-2 Q9Y4I1-3 Q9Y4I1-3 >sp|Q9Y4I1-3|MYO5A_HUMAN Isoform 3 of Myosin-Va OS=Homo sapiens GN=MYO5A;>sp|Q9Y4I1|MYO5A_HUMAN Myosin-Va OS=Homo sapiens GN=MYO5A PE=1 SV=2;>sp|Q9Y4I1-2|MYO5A_HUMAN Isoform 2 of Myosin-Va OS=Homo sapiens GN=MYO5A 0.324913 0 0.294232 -0.789395 0.0170434 66.646 0 0 0.324913 0 6.59295E-09 119.4 0 0 1 T TGLRKRTSSIADE CAMK2;FHA2 Rad53p;PKA 0.004788 6.59295E-09 119.4 _pTSSIADEGTYTLDSILR_ T(0.325)S(0.325)S(0.325)IADEGT(0.024)Y(0.001)TLDSILR T(0)S(0)S(0)IADEGT(-11.27)Y(-26.02)T(-32.56)LDS(-42.27)ILR 1 3 641.29787 0.1621 0 0 0 0 0 0 0 0 3436 1864 333 333 5896;5897;5898 6725;6726;6727 58152 35319 Mix4_InSol_TiO2_1 8035 58147 35317 Mix4_TiO2_Reinj_1_3 8030 Q9Y4K4 Q9Y4K4 Q9Y4K4 >sp|Q9Y4K4|M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens GN=MAP4K5 PE=1 SV=1 0.807337 6.22255 0.1393 -7.90902 0.00104547 83.973 0 0 0.438098 -1.0809 6.5108E-09 119.62 0.807337 6.22255 0.448173 32.522 0.807206 6.21892 0.929741 18.281 1 T NARAERTASEINF CK2 0.117 6.5108E-09 119.62 _pTASEINFDKLQFEPPLRK_ T(0.807)AS(0.193)EINFDKLQFEPPLRK T(6.22)AS(-6.22)EINFDKLQFEPPLRK 1 3 738.37159 -0.13606 587630 0 0 0 0 0 329840 257790 3437 1865 415 415 2513 2856 23654 14702 Mix4_TiO2_Reinj_1_4 3450 23653 14701 Mix4_TiO2_1_4 2838 Q9Y4P8;Q9Y4P8-4 Q9Y4P8 Q9Y4P8 >sp|Q9Y4P8|WIPI2_HUMAN WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 PE=1 SV=1;>sp|Q9Y4P8-4|WIPI2_HUMAN Isoform 4 of WD repeat domain phosphoinositide-interacting protein 2 OS=Homo sapiens GN=WIPI2 0.333268 0 0.00684703 -18.6048 0.0395075 49.475 0 0 0.333268 0 0.132967 35.341 0.245585 -1.63443 0.50662 12.658 0 0 1 T YVPSSPTRLAYTD CK1;FHA KAPP 0.081 0.0395075 49.475 _GTYVPpSSPTR_ GTYVPS(0.333)S(0.333)PT(0.333)R GT(-35.34)Y(-35.34)VPS(0)S(0)PT(0)R 9 2 572.75535 0.65132 0 0 0 0 0 0 0 0 3438 1870 2675 2675 206 238 2132 1401 Mix4_TiO2_Reinj_1_1 5755 2132 1401 Mix4_TiO2_Reinj_1_1 5755 Q9Y520-7;Q9Y520;Q9Y520-5;Q9Y520-4;Q9Y520-6;Q9Y520-3;Q9Y520-2 Q9Y520-7 Q9Y520-7 >sp|Q9Y520-7|BA2L2_HUMAN Isoform 7 of Protein BAT2-like 2 OS=Homo sapiens GN=BAT2L2;>sp|Q9Y520|BA2L2_HUMAN Protein BAT2-like 2 OS=Homo sapiens GN=BAT2L2 PE=1 SV=2;>sp|Q9Y520-5|BA2L2_HUMAN Isoform 5 of Protein BAT2-like 2 OS=Homo sapiens GN=BAT2L2;>sp|Q9Y52 0.999999 60.8272 0 0 0.999999 60.8272 0.0228049 60.827 0 0 0 0 1 T IDIKPGTPPIAGR ERK/MAPK;FHA2 Rad53p;Proline-directed 0.0025 0.0228049 60.827 _AFGSGIDIKPGpTPPIAGR_ AFGSGIDIKPGT(1)PPIAGR AFGS(-60.83)GIDIKPGT(60.83)PPIAGR 12 3 611.98014 -0.22534 65392 0 0 0 65392 0 0 0 3439 1890 616 616 4825 5475;5476;5477;5478 46061 28164 Mix4_TiO2_1_5 6113 46073 28167 Mix4_TiO2_1_5 5525 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.830673 9.40725 0.830673 9.40725 9.7911E-19 141.3 0 0 0.195957 -6.23072 0.000131814 90.693 0 0 0.250909 -2.43762 0.0420388 60.97 1 T ARRCSVTSMESTV CK2 0.117 9.7911E-19 141.3 _RCSVpTSMESTVSSGTQTTVQDDPEQFEVIK_ RCS(0.095)VT(0.831)S(0.045)MES(0.014)T(0.014)VS(0.001)SGTQTTVQDDPEQFEVIK RCS(-9.41)VT(9.41)S(-12.61)MES(-17.84)T(-17.84)VS(-28.15)S(-46.42)GT(-48.4)QT(-62.78)T(-68.41)VQDDPEQFEVIK 5 3 1142.8407 -0.062549 126220 126220 0 0 0 0 0 0 3440 1890 621 621 4825 5475;5476;5477;5478 46080 28170 Mix4_TiO2_1_1 5355 46084 28172 Mix4_TiO2_1_1 5876 Q9Y6D5 Q9Y6D5 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 0.465736 0 0.465736 0 7.78425E-06 98.351 0 0 0.338501 0 0.000131814 90.693 0 0 0.0220971 -12.9894 0.0420388 60.97 2 T VTSMESTVSSGTQ FHA KAPP;PLK1 0.033462 7.78425E-06 98.351 _RCpSVTSM(ox)EpSTVSSGTQTTVQDDPEQFEVIK_ RCS(0.429)VT(0.427)S(0.158)MES(0.466)T(0.466)VS(0.016)S(0.016)GT(0.016)QT(0.006)T(0.002)VQDDPEQFEVIK RCS(0)VT(0)S(-4.67)MES(0)T(0)VS(-15.06)S(-15.06)GT(-15.06)QT(-20.07)T(-24.45)VQDDPEQFEVIK 10 3 1174.8278 -0.13383 0 0 0 0 0 0 0 0 3441 1894 508 508 2926;3171 3330;3599;3600 30072 18714 Mix4_InSol_TiO2_1 4365 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.52866 1.37951 0.00112405 -29.2989 1.42096E-26 191.69 0.00330715 -21.4287 1.00596E-15 147.21 0.0642126 -11.5513 1.07972E-21 171.88 0 0 0.52866 1.37951 6.52093E-16 150.53 0.225581 -5.2308 5.8464E-26 180.71 1 T ITRKPVTVSPTTP 1.42096E-26 191.69 _KPVpTVSPTTPTSPTEGEAS_ KPVT(0.529)VS(0.385)PT(0.059)T(0.011)PT(0.004)S(0.004)PT(0.004)EGEAS(0.004) KPVT(1.38)VS(-1.38)PT(-9.56)T(-16.76)PT(-20.99)S(-20.99)PT(-20.99)EGEAS(-20.99) 4 3 655.97327 0.26985 124470 0.84948 0 0 0 0 0 124470 0 3442 1894 512 512 2926;3171 3330;3599;3600 30057 18705 Mix4_TiO2_1_4 3372 30054 18698 Mix4_InSol_TiO2_1 4110 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.862358 9.6023 0.862358 9.6023 2.89748E-21 165.07 0.454769 -0.0452948 1.00596E-15 147.21 0.643453 2.97004 6.72634E-26 178.55 0 0 0.283623 -3.44725 2.82981E-26 188.2 0.418243 0 5.8464E-26 180.71 2 T PVTVSPTTPTSPT 2.82981E-26 188.2 _KPVTVSPpTTPTpSPTEGEAS_ KPVTVS(0.043)PT(0.862)T(0.095)PT(0.053)S(0.947)PTEGEAS KPVT(-69.35)VS(-12.9)PT(9.6)T(-9.6)PT(-12.41)S(12.41)PT(-42.08)EGEAS(-64.03) 8 2 1023.4394 0.48894 3429700 23.407 825550 0 0 2604100 0 0 0 3443 1894 513 513 2926;3171 3330;3599;3600 27954 17386 Mix4_InSol_Tio2_Reinj_1 4464 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.418243 0 0.130953 -7.789 1.42096E-26 191.69 0.030549 -11.7732 1.00596E-15 147.21 0.0401303 -11.9555 6.72634E-26 178.55 0 0 0.093885 -3.37421 6.52093E-16 150.53 0.418243 0 5.8464E-26 180.71 1 T VTVSPTTPTSPTE CK1;ERK/MAPK;FHA KAPP;Proline-directed;WW GroupIV 0.0023175 1.42096E-26 191.69 _ITRKPVTVSPpTTPTSPTEGEAS_ ITRKPVT(0.001)VS(0.104)PT(0.418)T(0.418)PT(0.025)S(0.025)PT(0.007)EGEAS(0.002) IT(-36.41)RKPVT(-29.06)VS(-6.02)PT(0)T(0)PT(-12.27)S(-12.27)PT(-17.84)EGEAS(-23.18) 12 3 779.38422 -0.26155 0 0 0 0 0 0 0 0 0 3444 1894 515 515 2926;3171 3330;3599;3600 30073 18716 Mix4_InSol_TiO2_2 3178 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.98163 20.6385 0.940181 13.6701 1.42096E-26 191.69 0.675367 3.23024 1.00596E-15 147.21 0.66736 3.06988 1.07972E-21 171.88 0 0 0.98163 20.6385 6.52093E-16 150.53 0.876747 8.57347 5.8464E-26 180.71 1 T VSPTTPTSPTEGE 1.42096E-26 191.69 _KPVTVSPTTPpTSPTEGEAS_ KPVTVSPT(0.002)T(0.008)PT(0.982)S(0.003)PT(0.004)EGEAS(0.001) KPVT(-70.43)VS(-60.46)PT(-26.23)T(-20.64)PT(20.64)S(-25.48)PT(-23.91)EGEAS(-30.94) 11 2 983.45627 0.38106 8175900 55.799 1074400 99077 0 1835700 0 3329300 1837400 3445 1894 518 518 2926;3171 3330;3599;3600 27952 17384 Mix4_InSol_Tio2_Reinj_1 4330 30087 18734 Mix4_TiO2_1_4 3436 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 0.565745 1.16447 0.0928383 -7.29099 1.42096E-26 191.69 0.000222332 -34.8254 1.00596E-15 147.21 0.0246612 -13.8233 1.07972E-21 171.88 0 0 0.352725 1.3007 6.52093E-16 150.53 0.565745 1.16447 5.8464E-26 180.71 1 T TTPTSPTEGEAS_ CK2 0.117 1.42096E-26 191.69 _ITRKPVTVSPTTPTSPpTEGEAS_ ITRKPVTVSPTTPT(0.001)S(0.433)PT(0.566)EGEAS IT(-92.47)RKPVT(-95.12)VS(-76.34)PT(-64.11)T(-50.39)PT(-27.22)S(-1.16)PT(1.16)EGEAS(-30.61) 17 3 779.38422 -0.40284 570150 3.8912 0 0 0 0 0 0 570150 3446 1894 408 408 6527 7468;7469 65930 40434 Mix4_TiO2_Reinj_1_4 2100 65930 40434 Mix4_TiO2_Reinj_1_4 2100 Q9Y6G9 Q9Y6G9 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens GN=DYNC1LI1 PE=1 SV=3 1 61.0427 1 3.89631 0.552179 3.8963 0 0 1 61.0427 0.0105597 61.043 0 0 0 0 2 T PGGSPRTPNRSVS CDK1;CDK2;CK1;ERK/MAPK;Proline-directed;WW GroupIV 0.0023175 0.0105597 61.043 _VPGGpSPRpTPNR_ VPGGS(1)PRT(1)PNR VPGGS(61.04)PRT(61.04)PNR 8 2 649.27613 0.4167 164800 23278 0 0 141520 0 0 0 3447 1896 367 367 4284 4875 40771 25094 Mix4_InSol_Tio2_Reinj_2 3410 40769 25092 Mix4_InSol_Tio2_Reinj_1 4659 Q9Y6M4-3 Q9Y6M4-3 Q9Y6M4-3 >sp|Q9Y6M4-3|KC1G3_HUMAN Isoform 3 of Casein kinase I isoform gamma-3 OS=Homo sapiens GN=CSNK1G3 0.917111 11.1513 0 0 0.846504 8.25529 8.21218E-11 130.25 0.492432 0 4.55683E-16 145.45 0.917111 11.1513 1.59705E-26 181.3 1 T NQVVSSTNGELNT CK2 0.117 1.59705E-26 181.3 _NQVVSSpTNGELNTDDPTAGR_ NQVVS(0.013)S(0.07)T(0.917)NGELNTDDPTAGR NQVVS(-18.64)S(-11.15)T(11.15)NGELNT(-65.19)DDPT(-101.71)AGR 7 2 1077.9686 0.065469 450250 0 0 0 421160 0 0 29097 3448 1899 606 606 3251 3685 30745 19104 Mix4_TiO2_2_2 6315 30745 19104 Mix4_TiO2_2_2 6315 REV__A2RUS2;REV__A2RUS2-2 REV__A2RUS2 REV__A2RUS2 >sp|A2RUS2|DEND3_HUMAN DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 PE=2 SV=2;>sp|A2RUS2-2|DEND3_HUMAN Isoform 2 of DENN domain-containing protein 3 OS=Homo sapiens GN=DENND3 0.999999 62.0629 0.999999 62.0629 0.0194449 62.063 1 T RKTVLDTPFRIID CDK1;CDK2;Proline-directed 0.0057 0.0194449 62.063 _KTVLDpTPFRIIDK_ KTVLDT(1)PFRIIDK KT(-62.06)VLDT(62.06)PFRIIDK 6 2 813.43676 0.29188 84915 0 84915 0 0 0 0 0 + 3449 1916 2300 2300 5966 6803 58898 35747 Mix4_TiO2_Reinj_1_5 8915 58894 35743 Mix4_TiO2_1_1 7880 REV__Q0VDD8 REV__Q0VDD8 REV__Q0VDD8 >sp|Q0VDD8|DYH14_HUMAN Dynein heavy chain 14, axonemal OS=Homo sapiens GN=DNAH14 PE=2 SV=3 0.827919 6.82721 0.499856 0 0.0404496 58.243 0 0 0.827919 6.82721 0.209972 43.238 1 T NMVLVKTELGFCT NEK6 0.076 0.0404496 58.243 _pTELGFCTLVILSNPKLILATNK_ T(0.828)ELGFCT(0.172)LVILSNPKLILATNK T(6.83)ELGFCT(-6.83)LVILS(-37.56)NPKLILAT(-43.24)NK 1 3 842.45314 0.78798 1098100 0 0 0 1098100 0 0 0 + 3450 1916 2306 2306 5966 6803 58894 35743 Mix4_TiO2_1_1 7880 58894 35743 Mix4_TiO2_1_1 7880 REV__Q0VDD8 REV__Q0VDD8 REV__Q0VDD8 >sp|Q0VDD8|DYH14_HUMAN Dynein heavy chain 14, axonemal OS=Homo sapiens GN=DNAH14 PE=2 SV=3 0.883411 8.79602 0.883411 8.79602 0.0404496 58.243 0 0 0.675865 3.1958 0.209972 43.238 1 T TELGFCTLVILSN FHA2 Rad53p 0.114 0.0404496 58.243 _TELGFCpTLVILSNPKLILATNK_ T(0.117)ELGFCT(0.883)LVILSNPKLILATNK T(-8.8)ELGFCT(8.8)LVILS(-45.58)NPKLILAT(-58.24)NK 7 3 842.45314 0.5273 3547400 80034 0 0 3467300 0 0 0 + 3451 1925 32 32 6041 6890 59690 36218 Mix4_TiO2_Reinj_1_4 4794 59690 36218 Mix4_TiO2_Reinj_1_4 4794 REV__Q6UXM1;REV__Q6UXM1-2 REV__Q6UXM1 REV__Q6UXM1 >sp|Q6UXM1|LRIG3_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 3 OS=Homo sapiens GN=LRIG3 PE=2 SV=1;>sp|Q6UXM1-2|LRIG3_HUMAN Isoform 2 of Leucine-rich repeats and immunoglobulin-like domains protein 3 OS=Homo sapiens GN=LRIG3 0.999995 58.6352 0.999989 54.9322 0.0621116 54.932 0.999174 36.0204 0.330597 36.02 0.999995 58.6352 0.035289 58.635 2 T EEQFDRTKEGDEE 0.035289 58.635 _pTKEGDEESGSDLDPpSSHK_ T(1)KEGDEESGSDLDPS(0.551)S(0.449)HK T(58.64)KEGDEES(-52.55)GS(-53.67)DLDPS(0.89)S(-0.89)HK 1 2 1039.3854 0.13008 508060 94467 65031 0 348570 0 0 0 + 3452 1927 377 377 3389 3830 31929 19747 Mix4_TiO2_Reinj_1_4 3272 31927 19745 Mix4_TiO2_1_4 2711 REV__Q6ZWH5;REV__Q6ZWH5-5;REV__Q6ZWH5-6;REV__Q6ZWH5-7 REV__Q6ZWH5 REV__Q6ZWH5 >sp|Q6ZWH5|NEK10_HUMAN Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10 PE=2 SV=2;>sp|Q6ZWH5-5|NEK10_HUMAN Isoform 5 of Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10;>sp|Q6ZWH5-6|NEK10_HUMAN Isoform 6 of Serine/threonine-prot 0.966667 14.3543 0.999688 35.0521 0.0183594 65.368 0.979155 16.6982 0.0954962 43.201 0.966667 14.3543 0.0196132 64.18 3 T ELSLQSTSLNDLK NEK6 0.076 0.0183594 65.368 _LELpSLQSpTpSLNDLK_ LELS(0.975)LQS(0.092)T(0.967)S(0.967)LNDLK LELS(15.62)LQS(-14.35)T(14.35)S(14.35)LNDLK 8 2 900.8771 -1.0133 444460 78245 158110 0 208110 0 0 0 + 3453 1930 1065 1065 4519 5133 42806 26301 Mix4_TiO2_Reinj_1_1 2807 42806 26301 Mix4_TiO2_Reinj_1_1 2807 REV__Q7Z2Y8 REV__Q7Z2Y8 REV__Q7Z2Y8 >sp|Q7Z2Y8|GVIN1_HUMAN Interferon-induced very large GTPase 1 OS=Homo sapiens GN=GVIN1 PE=2 SV=2 1 77.7062 0 0 1 10.8542 0.572217 10.854 1 77.7062 0.00752256 77.706 1 T EELHGATKLDLFV CK2;FHA1 Rad53p 0.059 0.00752256 77.706 _QEHLEELHGApTK_ QEHLEELHGAT(1)K QEHLEELHGAT(77.71)K 11 2 736.33249 0.74319 209450 0 30958 0 178490 0 0 0 + 3454 51 180 180 1536;1537;1538;3548 1726;1727;1728;4002 14129 8617 Mix4_TiO2_1_1 3084 14137 8626 Mix4_TiO2_Reinj_1_6 3399 O00264 O00264 O00264 >sp|O00264|PGRC1_HUMAN Membrane-associated progesterone receptor component 1 OS=Homo sapiens GN=PGRMC1 PE=1 SV=3 0.482369 0 0.482369 0 7.68404E-07 110.44 0.401964 0 0.852105 25.633 0.118033 -8.73194 4.03593E-16 146.74 0 0 0.481734 0.793246 0.0643409 55.032 0.479568 0 0.0137115 65.304 1 Y GEEPTVYSDEEEP 4.03593E-16 146.74 _EGEEPTVpYSDEEEPKDESAR_ EGEEPT(0.034)VY(0.482)S(0.482)DEEEPKDES(0.002)AR EGEEPT(-11.57)VY(0)S(0)DEEEPKDES(-24.73)AR 8 3 792.65147 0.45965 0 0 0 0 0 0 0 0 3455 101 210 210 3549;3550 4003;4004 33504 20651 Mix4_TiO2_1_6 3200 33506 20653 Mix4_TiO2_Reinj_1_6 3800 O15173 O15173 O15173 >sp|O15173|PGRC2_HUMAN Membrane-associated progesterone receptor component 2 OS=Homo sapiens GN=PGRMC2 PE=1 SV=1 0.578375 1.3784 0.578375 1.3784 0.00102908 86.337 0.446956 0 2.0107E-10 133.05 1 Y GEEPSEYTDEEDT 2.0107E-10 133.05 _LLKPGEEPSEpYTDEEDTK_ LLKPGEEPSEY(0.578)T(0.421)DEEDTK LLKPGEEPS(-31.01)EY(1.38)T(-1.38)DEEDT(-38.44)K 11 3 720.64711 -0.27655 63072 63072 0 0 0 0 0 0 3456 220 171 171 4161 4737 39648 24464 Mix4_InSol_TiO2_1 5221 39648 24464 Mix4_InSol_TiO2_1 5221 O76039 O76039 O76039 >sp|O76039|CDKL5_HUMAN Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1 0.999999 62.7623 0.999181 31.5279 2.97078E-16 164.7 0.999663 34.7411 5.52532E-26 197.19 0.999999 62.7623 1.26612E-33 219.04 0.999697 35.2773 7.62412E-17 173.07 1 Y NANYTEYVATRWY 1.26612E-33 219.04 _NLSEGNNANYTEpYVATR_ NLSEGNNANYTEY(1)VATR NLS(-188.01)EGNNANY(-77.47)T(-62.76)EY(62.76)VAT(-69.14)R 13 2 998.42583 0.3574 371150 47629 0 0 135240 0 90361 97915 3457 272 480 480 4929;5484 5604;5605;6240;6241 47355 28923 Mix4_TiO2_Reinj_1_4 7222 53480 32677 Mix4_TiO2_Reinj_1_4 8225 O96013;O96013-4;O96013-3;O96013-2 O96013 O96013 >sp|O96013|PAK4_HUMAN Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4 PE=1 SV=1;>sp|O96013-4|PAK4_HUMAN Isoform 4 of Serine/threonine-protein kinase PAK 4 OS=Homo sapiens GN=PAK4;>sp|O96013-3|PAK4_HUMAN Isoform 3 of Serine/threonine-protein k 0.60322 1.88058 0.123593 -7.74157 3.50303E-16 169.97 0.462081 4.11123 0.131136 45.489 0.60322 1.88058 1.27668E-25 196.46 0.0371451 -13.3155 1.02856 15.413 0.102153 -8.3182 1.73432E-12 147.79 0.051445 -11.667 3.51023E-13 154.86 1 Y SLVGTPYWMAPEL 1.27668E-25 196.46 _RKSLVGTPpYWM(ox)APELISR_ RKS(0.006)LVGT(0.391)PY(0.603)WMAPELISR RKS(-20.37)LVGT(-1.88)PY(1.88)WMAPELIS(-43.9)R 9 4 550.78007 -0.30452 77124 0 0 0 77124 0 0 0 3458 276;552 412;439 439 3591 4048;4049 33775 20805 Mix4_InSol_Tio2_Reinj_1 3431 33775 20805 Mix4_InSol_Tio2_Reinj_1 3431 P00519-2;P00519;P42684;P42684-3;P42684-2;P42684-4 P00519-2;P42684 P42684 >sp|P00519-2|ABL1_HUMAN Isoform IB of Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1;>sp|P00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4;>sp|P42684|ABL2_HUMAN Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 0.980399 17.4707 0.879158 8.67365 2.01575E-17 110.2 0.980399 17.4707 1.14391E-06 125.46 1 Y LMTGDTYTAHAGA 1.14391E-06 125.46 _LMTGDTpYTAHAGAK_ LMT(0.001)GDT(0.018)Y(0.98)T(0.001)AHAGAK LMT(-32.51)GDT(-17.47)Y(17.47)T(-28.16)AHAGAK 7 2 758.82872 0.70547 76400 0 0 0 0 0 27097 49303 3459 277 1172 1172 2444 2771 22973 14367 Mix4_TiO2_Reinj_1_5 6881 22974 14368 Mix4_TiO2_Reinj_1_5 7141 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 1 84.2565 0.999941 42.4766 4.5762E-10 121.31 0 0 1 84.2565 1.55322E-15 142.1 3.34786E-05 -42.0669 0.168408 42.067 0.000722527 -30.35 0.586499 30.35 1 Y SLDNPDYQQDFFP 1.55322E-15 142.1 _GSHQISLDNPDpYQQDFFPK_ GSHQISLDNPDY(1)QQDFFPK GS(-102.22)HQIS(-84.26)LDNPDY(84.26)QQDFFPK 12 3 772.67047 0.095949 255170 59044 0 0 196120 0 0 0 3460 277 1197 1197 2473 2808 23215 14477 Mix4_TiO2_Reinj_1_5 3647 23215 14477 Mix4_TiO2_Reinj_1_5 3647 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 1 102.399 1 92.2923 0.00190219 92.292 0 0 1 102.399 0.00198218 105.08 1 Y TAENAEYLRVAPQ ALK;EGFR 0.143838 0.00198218 105.08 _GSTAENAEpYLR_ GSTAENAEY(1)LR GS(-102.4)T(-105.08)AENAEY(102.4)LR 9 2 645.77173 0.1335 225060 13.331 49552 0 0 175500 0 0 0 3461 277 1110 1110 4974 5656 47989 29338 Mix4_TiO2_Reinj_1_5 4329 47989 29338 Mix4_TiO2_Reinj_1_5 4329 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.998041 27.0721 0 0 0.998041 27.0721 2.92807E-11 127.49 1 Y SVQNPVYHNQPLN 2.92807E-11 127.49 _RPAGSVQNPVpYHNQPLNPAPSR_ RPAGS(0.002)VQNPVY(0.998)HNQPLNPAPSR RPAGS(-27.07)VQNPVY(27.07)HNQPLNPAPS(-112.48)R 11 3 827.07119 0.097602 358340 0 0 0 358340 0 0 0 3462 277 1069 1069 6806 7787 69057 42344 Mix4_TiO2_Reinj_1_5 8896 69056 42343 Mix4_TiO2_Reinj_1_5 8805 P00533 P00533 P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sapiens GN=EGFR PE=1 SV=2 0.315097 0 0.160567 0 6.55873E-08 108.39 0.169211 0 1.5362 30.095 0.315097 0 1.58055E-36 176.58 1 Y DSFLQRYSSDPTG 1.58055E-36 176.58 _pYSSDPTGALTEDSIDDTFLPVPEYINQSVPK_ Y(0.315)S(0.315)S(0.315)DPT(0.055)GALTEDSIDDTFLPVPEYINQSVPK Y(0)S(0)S(0)DPT(-7.61)GALT(-33.64)EDS(-60.2)IDDT(-70.31)FLPVPEY(-126.11)INQS(-126.07)VPK 1 3 1160.199 1.2817 0 0 0 0 0 0 0 0 0 3463 306 675 675 3791 4283 35982 22271 Mix4_TiO2_Reinj_1_3 8758 35982 22271 Mix4_TiO2_Reinj_1_3 8758 P05129 P05129 P05129 >sp|P05129|KPCG_HUMAN Protein kinase C gamma type OS=Homo sapiens GN=PRKCG PE=1 SV=3 0.499999 0 0.499999 0 6.59917E-08 113.06 1 Y DFQGFTYVNPDFV 6.59917E-08 113.06 _LVLASIDQADFQGFpTYVNPDFVHPDAR_ LVLASIDQADFQGFT(0.5)Y(0.5)VNPDFVHPDAR LVLAS(-55.29)IDQADFQGFT(0)Y(0)VNPDFVHPDAR 16 3 1039.1569 -0.7416 503130 0 0 0 503130 0 0 0 3464 315;332;373 420;426;425 425 3482;3483 3930;3932 32839 20362 Mix4_TiO2_Reinj_1_6 2836 32829 20335 Mix4_TiO2_1_3 2679 P06241;P06241-2;P06241-3;P07947;P12931-2;P12931;P06239-3;P06239 P06241;P07947;P12931-2 P12931-2 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN PE=1 SV=3;>sp|P06241-2|FYN_HUMAN Isoform T of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN;>sp|P06241-3|FYN_HUMAN Isoform 3 of Tyrosine-protein kinase Fyn OS=Homo sapiens GN=FYN; 0.999963 44.2932 0.999887 39.464 2.84663E-08 174.34 0.999195 30.9404 0.00179318 131.65 0.999963 44.2932 1.29324E-07 168.7 0.96684 14.6474 0.00282919 73.131 0.998849 29.3852 0.000135147 148.93 0.999028 30.1174 2.70637E-07 160.79 1 Y LIEDNEYTARQGA 2.84663E-08 174.34 _LIEDNEpYTAR_ LIEDNEY(1)TAR LIEDNEY(44.29)T(-44.29)AR 7 2 652.28193 0.2032 29210000 50.209 5305100 298390 0 18932000 14941 550760 4109000 3465 316 805 805 2858 3255;3256 27263 17037 Mix4_TiO2_1_5 6106 27262 17035 Mix4_TiO2_1_5 5936 P06400 P06400 P06400 >sp|P06400|RB_HUMAN Retinoblastoma-associated protein OS=Homo sapiens GN=RB1 PE=1 SV=2 0.5342 0.654189 0.5342 0.654189 3.5531E-12 138.49 0.248472 -6.52749 0.146457 41.649 2 Y IPGGNIYISPLKS ABL;EGFR 0.01638 3.5531E-12 138.49 _IPGGNIpYISPLKpSPYK_ IPGGNIY(0.534)IS(0.466)PLKS(0.858)PY(0.142)K IPGGNIY(0.65)IS(-0.65)PLKS(9.02)PY(-9.02)K 7 3 636.3087 -0.32783 145840 145840 0 0 0 0 0 0 3466 318 15 15 2745;2761;2763 3128;3129;3146;3147;3150;3151 26234 16362 Mix4_TiO2_Reinj_1_4 4633 26005 16095 Mix4_InSol_Tio2_Reinj_1 5448 P06493;P06493-2 P06493 P06493 >sp|P06493|CDK1_HUMAN Cell division protein kinase 1 OS=Homo sapiens GN=CDK1 PE=1 SV=2;>sp|P06493-2|CDK1_HUMAN Isoform CDC2deltaT of Cell division protein kinase 1 OS=Homo sapiens GN=CDK1 0.999886 39.4336 0.999717 35.4859 6.62147E-05 151.29 0.998936 29.7262 0.000213567 139.31 0 0 0.999886 39.4336 0.00306769 119.88 0.900773 9.57987 0.00305769 79.498 0.999717 35.4741 0.000167389 143.06 0.999544 33.4093 2.81479E-09 152.15 1 Y KIGEGTYGVVYKG ALK 0.2 2.81479E-09 152.15 _IGEGTpYGVVYK_ IGEGTY(1)GVVYK IGEGT(-39.43)Y(39.43)GVVY(-72.23)K 6 2 633.29431 0.44361 67998000 79.05 4205900 672330 0 42847000 230540 11919000 8123300 3467 318 19 19 2745;2761;2763 3128;3129;3146;3147;3150;3151 26240 16374 Mix4_TiO2_Reinj_1_6 4104 26005 16095 Mix4_InSol_Tio2_Reinj_1 5448 P06493;P06493-2 P06493 P06493 >sp|P06493|CDK1_HUMAN Cell division protein kinase 1 OS=Homo sapiens GN=CDK1 PE=1 SV=2;>sp|P06493-2|CDK1_HUMAN Isoform CDC2deltaT of Cell division protein kinase 1 OS=Homo sapiens GN=CDK1 0.999993 51.8025 0.660308 -0.123693 0.00144985 100.05 0.129526 -7.57429 0.000213567 139.31 0 0 0.999993 51.8025 0.00306769 119.88 0.122592 -7.89381 0.00305769 79.498 0.298689 -1.29677 0.000167389 143.06 0.183311 -5.38473 2.81479E-09 152.15 1 Y GTYGVVYKGRHKT 2.81479E-09 152.15 _IGEGTYGVVpYK_ IGEGTYGVVY(1)K IGEGT(-62.19)Y(-51.8)GVVY(51.8)K 10 2 633.29431 0.093947 24334 0.028289 10171 0 0 14162 0 0 0 3468 333;334 508;487 508 158 185 1740 1195 Mix4_TiO2_Reinj_2_1 5509 1738 1193 Mix4_TiO2_Reinj_2_2 3675 P07948;P07948-2 P07948;P07948-2 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3;>sp|P07948-2|LYN_HUMAN Isoform LYN B of Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN 0.998264 28.6365 0 0 0 0 0.955745 14.3244 0.00010138 92.352 0.998264 28.6365 3.9264E-12 119.56 1 Y TATEGQYQQQP__ 3.9264E-12 119.56 _AEERPTFDYLQSVLDDFYTATEGQpYQQQP_ AEERPTFDYLQSVLDDFYTAT(0.001)EGQY(0.998)QQQP AEERPT(-98.59)FDY(-99.64)LQS(-96.69)VLDDFY(-41.58)T(-35.23)AT(-28.64)EGQY(28.64)QQQP 25 3 1173.847 0.031934 830390 0 0 0 355590 474810 0 0 3469 333;334 194;173 194 5422 6171 52858 32304 Mix4_InSol_TiO2_1 5523 52858 32304 Mix4_InSol_TiO2_1 5523 P07948;P07948-2 P07948;P07948-2 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3;>sp|P07948-2|LYN_HUMAN Isoform LYN B of Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN 0.872117 8.33769 0 0 0.855712 7.74131 0.134582 36.985 0.872117 8.33769 0.00859159 75.776 0 0 1 Y LDNGGYYISPRIT 0.00859159 75.776 _SLDNGGYpYISPR_ SLDNGGY(0.128)Y(0.872)ISPR S(-75.69)LDNGGY(-8.34)Y(8.34)IS(-55.74)PR 8 2 711.30848 0.27883 216810 0 0 0 143660 0 73150 0 3470 333 32 32 6035 6884 59653 36197 Mix4_InSol_TiO2_1 4156 59653 36197 Mix4_InSol_TiO2_1 4156 P07948 P07948 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3 0.999685 35.0395 0.999685 35.0395 0.00599192 72.28 0.997997 26.9878 0.0277295 55.24 1 Y NTERTIYVRDPTS 0.00599192 72.28 _TIpYVRDPTSNK_ TIY(1)VRDPTSNK T(-35.04)IY(35.04)VRDPT(-58.03)S(-72.28)NK 3 2 687.32667 0.71582 126130 0 0 0 0 0 74318 51817 3471 333;334 397;376 397 6434;6435 7360;7362 64990 39857 Mix4_InSol_TiO2_1 3010 65024 39903 Mix4_InSol_TiO2_1 3167 P07948;P08631;P08631-2;P07948-2 P07948;P07948-2 P07948 >sp|P07948|LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo sapiens GN=LYN PE=1 SV=3;>sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens GN=HCK PE=1 SV=5;>sp|P08631-2|HCK_HUMAN Isoform p59-HCK of Tyrosine-protein kinase HCK OS=Homo sapiens GN=HCK 0.99994 42.2019 0.999896 39.8396 0.000319922 138.35 0.982636 17.5275 0.00521034 117.9 0.999076 30.3377 0.00521034 117.9 0.9929 21.4564 0.0194037 56.131 0.99994 42.2019 9.7793E-09 140.88 0.998851 29.3937 1.04999E-08 139.72 1 Y VIEDNEYTAREGA 9.7793E-09 140.88 _VIEDNEpYTAR_ VIEDNEY(1)TAR VIEDNEY(42.2)T(-42.2)AR 7 2 645.27411 -0.66413 44288000 405.76 5931200 505500 0 25222000 32970 6103900 6492700 3472 344 61 61 5486 6243 53553 32750 Mix4_InSol_TiO2_2 4132 53558 32756 Mix4_TiO2_Reinj_1_4 5146 P08670 P08670 P08670 >sp|P08670|VIME_HUMAN Vimentin OS=Homo sapiens GN=VIM PE=1 SV=4 0.585321 2.3097 0.183253 -6.39892 1.59289E-06 120.73 0.0121875 -19.0414 0.00147538 91.248 0.0406963 -13.6594 4.58367E-07 132.67 0.585321 2.3097 4.7477E-07 132.5 0.0040527 -23.899 1.77969E-06 118.77 1 Y SSPGGVYATRSSA 4.58367E-07 132.67 _SLYASSPGGVpYATR_ SLYAS(0.068)S(0.344)PGGVY(0.585)AT(0.003)R S(-43.91)LY(-43.91)AS(-9.37)S(-2.31)PGGVY(2.31)AT(-22.84)R 11 2 754.84269 0.42323 41636 0 0 0 0 0 41636 0 3473 392 714 714 4514 5127 42782 26289 Mix4_InSol_Tio2_Reinj_1 3487 42784 26291 Mix4_TiO2_Reinj_1_3 3227 P16591 P16591 P16591 >sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens GN=FER PE=1 SV=2 0.96665 15.3118 0.819314 7.71016 0.0743044 45.741 0.874015 9.00663 0.00413465 82.311 0.616947 3.0579 0.378749 23.073 0.96665 15.3118 0.0173445 64.534 1 Y QEDGGVYSSSGLK 0.00413465 82.311 _QEDGGVpYSSSGLK_ QEDGGVY(0.967)S(0.028)S(0.004)S(0.001)GLK QEDGGVY(15.31)S(-15.31)S(-23.58)S(-31.68)GLK 7 2 703.7954 0.64379 444720 16.457 59752 0 0 227360 0 90846 66761 3474 392 402 402 6557 7500 66340 40727 Mix4_TiO2_Reinj_1_3 4216 66338 40725 Mix4_TiO2_1_3 3671 P16591 P16591 P16591 >sp|P16591|FER_HUMAN Tyrosine-protein kinase Fer OS=Homo sapiens GN=FER PE=1 SV=2 1 195.375 1 157.301 2.08249E-39 220.63 1 195.375 6.21775E-32 195.37 1 154.096 1.04707E-16 154.1 1 162.907 9.96284E-22 162.91 1 Y PPPVVNYEEDARS 2.08249E-39 220.63 _VQENDGKEPPPVVNpYEEDAR_ VQENDGKEPPPVVNY(1)EEDAR VQENDGKEPPPVVNY(195.37)EEDAR 15 3 789.01631 -0.66391 2992500 1.0074 809820 0 0 1721000 0 234190 227520 3475 396 658 658 2387 2704 22241 13861 Mix4_TiO2_Reinj_1_5 9030 22244 13864 Mix4_TiO2_Reinj_2_1 5493 P17252 P17252 P17252 >sp|P17252|KPCA_HUMAN Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=3 0.874294 8.6033 0.874294 8.6033 0.00188773 91.836 0.621386 2.98702 1.73627E-06 109.54 2 Y DFEGFSYVNPQFV 1.73627E-06 109.54 _GQPVLpTPPDQLVIANIDQSDFEGFSpYVNPQFVHPILQSAV_ GQPVLT(0.999)PPDQLVIANIDQS(0.006)DFEGFS(0.121)Y(0.874)VNPQFVHPILQSAV GQPVLT(32.84)PPDQLVIANIDQS(-22.74)DFEGFS(-8.6)Y(8.6)VNPQFVHPILQS(-41.16)AV 26 3 1514.0553 0.40194 2902300 0 0 0 2557800 344520 0 0 3476 441 15 15 2761;2762;6384 3146;3147;3149;7304;7305 26234 16362 Mix4_TiO2_Reinj_1_4 4633 26202 16287 Mix4_TiO2_1_6 3226 P24941;Q00526 P24941 P24941 >sp|P24941|CDK2_HUMAN Cell division protein kinase 2 OS=Homo sapiens GN=CDK2 PE=1 SV=2;>sp|Q00526|CDK3_HUMAN Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1 0.999886 39.4336 0.999717 35.4859 6.62147E-05 151.29 0.998936 29.7262 0.000213567 139.31 0 0 0.999886 39.4336 0.00306769 119.88 0.900773 9.57987 0.00305769 79.498 0.999717 35.4741 0.000167389 143.06 0.999544 33.4093 4.23009E-09 149.86 1 Y KIGEGTYGVVYKA ALK 0.2 6.62147E-05 151.29 _IGEGTpYGVVYK_ IGEGTY(1)GVVYK IGEGT(-39.43)Y(39.43)GVVY(-72.23)K 6 2 633.29431 0.44361 69538000 80.84 4205900 672330 0 42909000 230540 12462000 9057500 3477 441 19 19 2761;2762;6384 3146;3147;3149;7304;7305 26240 16374 Mix4_TiO2_Reinj_1_6 4104 26202 16287 Mix4_TiO2_1_6 3226 P24941;Q00526 P24941 P24941 >sp|P24941|CDK2_HUMAN Cell division protein kinase 2 OS=Homo sapiens GN=CDK2 PE=1 SV=2;>sp|Q00526|CDK3_HUMAN Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1 0.999993 51.8025 0.660308 -0.123693 0.00144985 100.05 0.129526 -7.57429 0.000213567 139.31 0 0 0.999993 51.8025 0.00306769 119.88 0.122592 -7.89381 0.00305769 79.498 0.298689 -1.29677 0.000167389 143.06 0.183311 -5.38473 4.23009E-09 149.86 1 Y GTYGVVYKARNKL 6.62147E-05 151.29 _IGEGTYGVVpYK_ IGEGTYGVVY(1)K IGEGT(-62.19)Y(-51.8)GVVY(51.8)K 10 2 633.29431 0.093947 24334 0.028289 10171 0 0 14162 0 0 0 3478 441 159 159 6318 7218 63216 38531 Mix4_TiO2_1_2 6103 63239 38566 Mix4_TiO2_Reinj_1_6 6696 P24941;Q00526 P24941 P24941 >sp|P24941|CDK2_HUMAN Cell division protein kinase 2 OS=Homo sapiens GN=CDK2 PE=1 SV=2;>sp|Q00526|CDK3_HUMAN Cell division protein kinase 3 OS=Homo sapiens GN=CDK3 PE=1 SV=1 0.358889 0 0.358889 0 3.82434E-06 151.44 0.00449497 -23.1098 0.0421883 53.183 0.33333 0 3.10519E-13 187.76 0.13905 -5.51615 0.000581395 109.48 0.333186 0 8.95467E-05 124.47 0.197152 -4.87454 0.0058844 81.798 1 Y GVPVRTYTHEVVT 3.10519E-13 187.76 _pTYTHEVVTLWYR_ T(0.359)Y(0.359)T(0.094)HEVVT(0.094)LWY(0.094)R T(0)Y(0)T(-5.81)HEVVT(-5.81)LWY(-5.81)R 2 2 824.38198 0.090799 0 0 0 0 0 0 0 0 3479 450 204 204 2692 3065;3066 25284 15609 Mix4_InSol_TiO2_1 6569 25308 15651 Mix4_TiO2_Reinj_1_4 5898 P27361 P27361 P27361 >sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 OS=Homo sapiens GN=MAPK3 PE=1 SV=4 0.999772 39.4207 0.998508 28.5528 1.87145E-15 139.09 0.908179 10.3478 0.00547165 75.219 0.998409 28.3645 3.74699E-21 161.88 0.992329 22.6573 0.0156285 65.098 0.999772 39.4207 1.36296E-15 143.88 0.998317 28.3764 3.28325E-07 116.65 1 Y TGFLTEYVATRWY 3.74699E-21 161.88 _IADPEHDHTGFLTEpYVATR_ IADPEHDHTGFLTEY(1)VATR IADPEHDHT(-136.9)GFLT(-39.42)EY(39.42)VAT(-39.42)R 15 3 751.33884 -0.35304 37863000 2142400 36665 0 28941000 24750 3334600 3383300 3480 451;452 441;425 441 5080 5777 49136 30015 Mix4_TiO2_Reinj_1_5 6029 49135 30014 Mix4_TiO2_Reinj_1_3 6054 P27448;P27448-5;P27448-2;P27448-4;P27448-3;P27448-7;P27448-6 P27448;P27448-7 P27448 >sp|P27448|MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3;>sp|P27448-5|MARK3_HUMAN Isoform 5 of MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3;>sp|P27448-2|MARK3_HUMAN Isoform CTAK75a of M 0.86237 7.96982 0.166282 -7.00173 0.0128414 69.616 0 0 0.86237 7.96982 1.16808E-06 114.81 0 0 0 0 1 Y SQKQRRYSDHAGP 1.16808E-06 114.81 _RpYSDHAGPAIPSVVAYPK_ RY(0.862)S(0.138)DHAGPAIPSVVAYPK RY(7.97)S(-7.97)DHAGPAIPS(-87.95)VVAY(-87.95)PK 2 3 669.99445 0.15312 294260 0 0 0 294260 0 0 0 3481 463 187 187 6326 7230;7231 63428 38713 Mix4_TiO2_1_4 5499 63430 38730 Mix4_TiO2_1_4 6576 P28482 P28482 P28482 >sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 OS=Homo sapiens GN=MAPK1 PE=1 SV=3 0.999976 49.1815 0.999976 49.1815 9.74781E-27 192.82 0.963121 14.6803 4.27442E-06 99.111 0.999924 41.26 2.34113E-21 167.16 0.998461 28.2271 3.75126E-10 124.21 0.999255 33.754 2.26358E-10 129.44 0.999312 32.1685 1.35328E-10 132.61 1 Y TGFLTEYVATRWY 9.74781E-27 192.82 _VADPDHDHTGFLTEpYVATR_ VADPDHDHTGFLTEY(1)VATR VADPDHDHT(-140.48)GFLT(-49.18)EY(49.18)VAT(-49.18)R 15 3 741.99507 -0.23712 211550000 125.38 29761000 154750 0 135260000 156570 31914000 14300000 3482 465 575 575 469;4737 533;5380 45152 27633 Mix4_TiO2_Reinj_1_5 4718 4401 2666 Mix4_TiO2_Reinj_1_5 4893 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.999999 58.7158 0.99986 38.5401 0.000697221 107.29 0.0153179 -18.0129 0.176426 24.211 0.999999 58.7158 6.11331E-05 129.31 0 0 0.809261 6.30731 6.94551E-05 127.89 0.695002 6.5872 0.000125169 118.34 1 Y QSPEDVYFSKSEQ 6.11331E-05 129.31 _QSPEDVpYFSK_ QSPEDVY(1)FSK QS(-86.5)PEDVY(58.72)FS(-58.72)K 7 2 640.26575 0.25271 3173800 3.6138 739380 0 0 2316100 0 64123 54138 3483 465 960 960 2706 3082 25546 15784 Mix4_TiO2_Reinj_1_5 6984 25546 15784 Mix4_TiO2_Reinj_1_5 6984 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.999588 33.8453 0.484307 -0.272706 0.407399 19.396 0.999588 33.8453 0.00333986 72.82 1 Y HQKRIAYSLLGLK ALK 0.2 0.00333986 72.82 _IApYSLLGLK_ IAY(1)SLLGLK IAY(33.85)S(-33.85)LLGLK 3 2 529.2883 -0.18469 63579 10.17 0 0 0 63579 0 0 0 3484 465 588 588 6319 7219;7220 63322 38607 Mix4_TiO2_Reinj_1_5 4728 63321 38606 Mix4_TiO2_1_5 4105 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.900568 9.6105 0.499971 0 1.4034E-12 140.78 7.37447E-05 -40.3465 0.176563 40.346 0.900568 9.6105 0.0068737 75.386 0 0 0.0441039 -10.1439 8.58534E-06 101.85 0.0252257 -15.0488 2.80274E-09 129.75 2 Y LKPLKTYVDPHTY 1.4034E-12 140.78 _TpYVDPHpTYEDPNQAVLK_ T(0.099)Y(0.901)VDPHT(0.584)Y(0.416)EDPNQAVLK T(-9.61)Y(9.61)VDPHT(1.48)Y(-1.48)EDPNQAVLK 2 3 717.30082 -0.00045089 3326400 2.5224 647430 0 0 2679000 0 0 0 3485 465 594 594 6319 7219;7220 63293 38598 Mix4_TiO2_2_2 4040 63288 38593 Mix4_TiO2_1_5 4286 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.79869 5.98831 0.8998 9.21551 1.4034E-12 140.78 0.79869 5.98831 0.176563 40.346 0.5 0 4.76407E-06 109.09 0 0 0.549958 0.870874 8.58534E-06 101.85 0.452851 -0.821334 2.80274E-09 129.75 1 Y YVDPHTYEDPNQA 1.20158E-12 143.04 _TYVDPHTpYEDPNQAVLK_ TYVDPHT(0.201)Y(0.799)EDPNQAVLK T(-40.35)Y(-40.35)VDPHT(-5.99)Y(5.99)EDPNQAVLK 8 2 1035.4644 0.494 2860200 2.1688 1657800 93994 0 331500 0 776860 0 3486 465 628 628 6436 7363 65045 39915 Mix4_TiO2_Reinj_1_5 5940 65044 39914 Mix4_TiO2_1_5 5092 P29317;P54762 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2;>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens GN=EPHB1 PE=1 SV=1 1 75.0986 1 77.7852 0.00749209 77.785 1 75.0986 0.00896628 75.099 1 Y GEFGEVYKGMLKT ALK 0.2 0.00749209 77.785 _VIGAGEFGEVpYK_ VIGAGEFGEVY(1)K VIGAGEFGEVY(75.1)K 11 2 674.81287 -0.21627 93072 0.92362 17687 0 0 75386 0 0 0 3487 465 772 772 6467;6468 7397;7399 65321 40060 Mix4_TiO2_1_5 3220 65319 40056 Mix4_TiO2_1_4 3218 P29317 P29317 P29317 >sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens GN=EPHA2 PE=1 SV=2 0.997758 27.5339 0.997758 27.5339 2.4347E-54 269.2 0.883089 8.82966 1.08721E-15 157.36 0.983004 18.0042 1.75089E-20 191.59 0.807488 6.67521 0.0147885 69.135 0.983393 18.4279 2.39891E-16 150.77 0.988665 20.6463 2.88773E-16 149.56 1 Y DDPEATYTTSGGK SRC 0.047736 2.4347E-54 269.2 _VLEDDPEATpYTTSGGK_ VLEDDPEATY(0.998)T(0.002)TSGGK VLEDDPEAT(-37.35)Y(27.53)T(-27.53)T(-35.86)S(-44.06)GGK 10 3 588.25215 0.68744 19158000 7.1339 4819300 131550 0 11287000 36170 1373400 1511300 3488 470 292 292 3518 3971 33225 20522 Mix4_TiO2_Reinj_1_5 5241 33223 20519 Mix4_TiO2_1_5 4475 P29597 P29597 P29597 >sp|P29597|TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens GN=TYK2 PE=1 SV=3 1 141.296 1 24.0581 6.51299E-08 156.46 1 141.296 4.41943E-06 141.3 0 0 0 0 1 Y AEGEPCYIRDSGV EGFR;SRC 0.047736 6.51299E-08 156.46 _LLAQAEGEPCpYIR_ LLAQAEGEPCY(1)IR LLAQAEGEPCY(141.3)IR 11 2 800.36547 -0.043535 1911000 347850 0 0 1563200 0 0 0 3489 487 120 120 4819 5469 46009 28145 Mix4_InSol_TiO2_2 3580 46015 28151 Mix4_TiO2_Reinj_1_4 4359 P31323 P31323 P31323 >sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens GN=PRKAR2B PE=1 SV=3 0.571402 1.28728 5.00572E-07 -63.0053 8.03899E-17 149.71 0 0 5.13225E-05 -42.8967 1.49447E-23 156.79 0.571402 1.28728 9.5925E-07 99.159 0.011917 -19.1859 4.68093E-11 125.91 1 Y SVCAEAYNPDEEE EGFR 0.143838 1.49447E-23 156.79 _RASVCAEApYNPDEEEDDAESR_ RAS(0.425)VCAEAY(0.571)NPDEEEDDAES(0.004)R RAS(-1.29)VCAEAY(1.29)NPDEEEDDAES(-21.81)R 9 3 831.65511 0.11105 29966 0 0 0 0 0 29966 0 3490 523 11 11 4426 5035 42115 25949 Mix4_TiO2_1_4 4419 42116 25950 Mix4_TiO2_1_4 4438 P36578 P36578 P36578 >sp|P36578|RL4_HUMAN 60S ribosomal protein L4 OS=Homo sapiens GN=RPL4 PE=1 SV=5 0.237345 0 0.237345 0 0.000947384 93.017 0 0 0.0542987 -11.8385 0.692218 19.264 1 Y RPLISVYSEKGES 0.000947384 93.017 _PLISVpYSEKGESSGK_ PLIS(0.051)VY(0.237)S(0.237)EKGES(0.237)S(0.237)GK PLIS(-6.71)VY(0)S(0)EKGES(0)S(0)GK 6 3 554.26584 -0.093431 0 0 0 0 0 0 0 0 3491 547 2449 2449 5950;6204;6205 6786;6787;7087;7088;7089 61530 37295 Mix4_TiO2_Reinj_1_5 6759 61495 37270 Mix4_TiO2_1_1 5909 P42345 P42345 P42345 >sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1 0.507013 2.0315 0.28031 0 1.36597E-25 160.21 0.280298 0 0.000152987 90.238 0.507013 2.0315 1.61746E-25 157.31 0 0 0.102317 -5.69445 1.63028 25.351 0.365363 0 0.000169646 89.325 1 Y RTRTDSYSAGQSV 1.36597E-25 160.21 _TRTDSpYSAGQSVEILDGVELGEPAHKK_ T(0.002)RT(0.002)DS(0.318)Y(0.507)S(0.066)AGQS(0.105)VEILDGVELGEPAHKK T(-24.09)RT(-24.09)DS(-2.03)Y(2.03)S(-8.82)AGQS(-6.84)VEILDGVELGEPAHKK 6 3 989.80803 -0.21984 689350 0 0 0 689350 0 0 0 3492 553 46 46 2589 2944 24233 15034 Mix4_TiO2_Reinj_1_4 7729 24233 15034 Mix4_TiO2_Reinj_1_4 7729 P42685 P42685 P42685 >sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens GN=FRK PE=1 SV=1 1 66.9677 1 66.9677 0.0166949 66.968 1 Y SQRHGHYFVALFD 0.0166949 66.968 _HGHpYFVALFDYQAR_ HGHY(1)FVALFDYQAR HGHY(66.97)FVALFDY(-66.97)QAR 4 3 601.93828 -0.15025 55659 0 0 0 55659 0 0 0 3493 558 597 597 5877;5878 6702;6703;6704 57974 35226 Mix4_InSol_Tio2_Reinj_2 1574 57954 35213 Mix4_TiO2_1_5 1935 P43243 P43243 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MATR3 PE=1 SV=2 0.263372 0 0.00622074 -21.9521 0.000235909 111.74 0 0 0.118497 -11.0985 0.00016937 103.58 0.00178657 -27.3026 7.09412E-07 130.03 0.263372 0 0.0228003 61.162 1 Y KSRKRSYSPDGKE 0.000235909 111.74 _pSYSPDGKESPSDKK_ S(0.263)Y(0.263)S(0.227)PDGKES(0.123)PS(0.123)DKK S(0)Y(0)S(-0.65)PDGKES(-3.3)PS(-3.3)DKK 2 2 802.84562 0.063599 0 0 0 0 0 0 0 0 3494 564 185 185 5887 6714 58069 35264 Mix4_InSol_TiO2_1 7665 58070 35265 Mix4_InSol_Tio2_Reinj_1 7629 P45983-2;P45983-3;P45983;P45983-4;P53779;P53779-2 P45983-2 P45983-2 >sp|P45983-2|MK08_HUMAN Isoform JNK1-alpha-1 of Mitogen-activated protein kinase 8 OS=Homo sapiens GN=MAPK8;>sp|P45983-3|MK08_HUMAN Isoform JNK1-beta-1 of Mitogen-activated protein kinase 8 OS=Homo sapiens GN=MAPK8;>sp|P45983|MK08_HUMAN Mitogen-activated p 0.995096 25.4073 0.995096 25.4073 0.00191772 86.438 0.992949 21.4875 9.44154E-12 161.2 1 Y SFMMTPYVVTRYY 9.44154E-12 161.2 _TAGTSFMMTPpYVVTR_ TAGTSFMMT(0.002)PY(0.995)VVT(0.003)R T(-83.51)AGT(-82.88)S(-84.13)FMMT(-26.89)PY(25.41)VVT(-25.41)R 11 2 871.38809 -0.034641 216940 0 0 0 0 0 101210 115740 3495 565 185 185 5881 6708 58010 35245 Mix4_InSol_TiO2_1 6665 58010 35245 Mix4_InSol_TiO2_1 6665 P45984-2;P45984-3;P45984;P45984-4 P45984-2 P45984-2 >sp|P45984-2|MK09_HUMAN Isoform Alpha-1 of Mitogen-activated protein kinase 9 OS=Homo sapiens GN=MAPK9;>sp|P45984-3|MK09_HUMAN Isoform Beta-1 of Mitogen-activated protein kinase 9 OS=Homo sapiens GN=MAPK9;>sp|P45984|MK09_HUMAN Mitogen-activated protein kin 0.99512 23.1476 0.99512 23.1476 0.00235174 83.519 0 0 1 Y NFMMTPYVVTRYY 0.00235174 83.519 _TACTNFM(ox)MTPpYVVTR_ TACTNFMMT(0.005)PY(0.995)VVTR T(-81.39)ACT(-68.51)NFMMT(-23.15)PY(23.15)VVT(-65.39)R 11 2 944.39559 0.89383 38335 0 0 0 0 0 38335 0 3496 590 13 13 4962;5028 5643;5719 48544 29681 Mix4_InSol_Tio2_Reinj_1 3122 47893 29286 Mix4_InSol_Tio2_Reinj_1 3268 P49207 P49207 P49207 >sp|P49207|RL34_HUMAN 60S ribosomal protein L34 OS=Homo sapiens GN=RPL34 PE=1 SV=3 0.35442 0 0 0 0 0 0 0 0.189402 -3.57893 0.00491623 66.695 0.35442 0 0.00389839 123.37 1 Y YRRRLSYNTASNK 0.00389839 123.37 _RRLpSYNTASNK_ RRLS(0.354)Y(0.354)NT(0.146)AS(0.146)NK RRLS(0)Y(0)NT(-3.86)AS(-3.86)NK 5 2 695.33536 0.19961 0 0 0 0 0 0 0 0 3497 600;1624 331;329 331 6649 7612;7613 67444 41436 Mix4_TiO2_1_5 4943 67443 41435 Mix4_TiO2_1_4 5002 P49759;Q9HAZ1 P49759;Q9HAZ1 P49759 >sp|P49759|CLK1_HUMAN Dual specificity protein kinase CLK1 OS=Homo sapiens GN=CLK1 PE=1 SV=2;>sp|Q9HAZ1|CLK4_HUMAN Dual specificity protein kinase CLK4 OS=Homo sapiens GN=CLK4 PE=1 SV=1 0.39811 0 0.39811 0 2.25458E-32 184.37 5.67647E-05 -40.1648 0.0298721 58.973 0.056489 -6.40143 2.19665E-16 137.65 0.15576 0 0.69416 31.087 0.0565698 -6.85477 8.61479E-07 101.09 0.0551708 -9.18764 0.0838124 53.592 1 Y DFGSATYDDEHHS EGFR 0.143838 2.25458E-32 184.37 _VVDFGSApTYDDEHHSTLVSTR_ VVDFGS(0.005)AT(0.398)Y(0.398)DDEHHS(0.017)T(0.08)LVS(0.08)T(0.021)R VVDFGS(-19)AT(0)Y(0)DDEHHS(-13.61)T(-6.95)LVS(-6.95)T(-12.81)R 9 3 806.01994 0.29274 0 0 0 0 0 0 0 0 3498 609;610 279;216 279 2174;4645 2460;2461;5271 19947 12216 Mix4_InSol_Tio2_Reinj_2 3546 19937 12184 Mix4_InSol_TiO2_1 5014 P49840;P49841-2;P49841 P49840;P49841-2 P49840 >sp|P49840|GSK3A_HUMAN Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2;>sp|P49841-2|GSK3B_HUMAN Isoform 2 of Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B;>sp|P49841|GSK3B_HUMAN Glycogen synthase kinase-3 beta OS=Homo sapiens 0.999606 34.0423 0.904458 9.76196 0.00243643 109.37 0.208746 -5.75792 0.00253535 85.244 0.987614 19.0178 0.00297666 114.47 0.432528 -1.17596 0.15316 34.34 0.998909 29.6168 0.000140081 145.28 0.999606 34.0423 0.000945782 132.99 1 Y GEPNVSYICSRYY 0.000140081 145.28 _GEPNVSpYICSR_ GEPNVSY(1)ICSR GEPNVS(-34.04)Y(34.04)ICS(-80.34)R 7 2 681.28141 -0.54927 117640000 447.08 13998000 0 0 56703000 0 26126000 20816000 3499 614 169 169 649;5267 747;5995 51121 31340 Mix4_InSol_TiO2_2 3510 51124 31345 Mix4_InSol_Tio2_Reinj_1 4641 P50613 P50613 P50613 >sp|P50613|CDK7_HUMAN Cell division protein kinase 7 OS=Homo sapiens GN=CDK7 PE=1 SV=1 0.780213 7.18424 0.287924 -1.68245 0.00374896 121.96 0.106047 -9.21265 0.00456835 118.35 0.000664174 -31.7738 0.00434361 115.7 0.164524 -6.10461 0.0579388 44.54 0.780213 7.18424 7.85565E-06 107.13 0.486266 0.326229 1.18723E-06 116.44 2 Y GSPNRAYTHQVVT 1.18723E-06 116.44 _pSFGSPNRApYTHQVVTR_ S(0.7)FGS(0.262)PNRAY(0.78)T(0.181)HQVVT(0.077)R S(4.73)FGS(-4.73)PNRAY(7.18)T(-7.18)HQVVT(-14.59)R 9 2 990.42987 -0.15199 243830 0 0 0 0 0 243830 0 3500 617 302 302 4321 4914 41036 25257 Mix4_TiO2_Reinj_1_4 1740 41031 25234 Mix4_TiO2_1_4 1460 P50750-2;P50750 P50750-2 P50750-2 >sp|P50750-2|CDK9_HUMAN Isoform 2 of Cell division protein kinase 9 OS=Homo sapiens GN=CDK9;>sp|P50750|CDK9_HUMAN Cell division protein kinase 9 OS=Homo sapiens GN=CDK9 PE=1 SV=3 0.736817 4.47106 0.498318 0 0.00482119 66.988 0 0 0.736817 4.47106 0.00498774 66.474 0 0 0.499715 0 0.204259 29.433 0.374623 0 0.352039 19.333 1 Y NSQPNRYTNRVVT 0.00482119 66.988 _NSQPNRpYTNR_ NSQPNRY(0.737)T(0.263)NR NS(-55.27)QPNRY(4.47)T(-4.47)NR 7 2 665.28841 -1.6337 11000000 0 0 0 11000000 0 0 0 3501 627 19 19 138 161;162;163 1442 902 Mix4_TiO2_1_6 4850 1443 903 Mix4_TiO2_Reinj_1_6 5591 P51636;P51636-3 P51636 P51636 >sp|P51636|CAV2_HUMAN Caveolin-2 OS=Homo sapiens GN=CAV2 PE=1 SV=2;>sp|P51636-3|CAV2_HUMAN Isoform C of Caveolin-2 OS=Homo sapiens GN=CAV2 0.572192 0 0.572192 0 0.140273 54.626 0.46023 0 0.0151577 66.573 2 Y FMDDDSYSHHSGL 0.0151577 66.573 _ADVQLFM(ox)DDDSpYpSHHSGLEYADPEK_ ADVQLFMDDDS(0.177)Y(0.572)S(0.572)HHS(0.577)GLEY(0.101)ADPEK ADVQLFMDDDS(-6.27)Y(0)S(0)HHS(0)GLEY(-8.41)ADPEK 12 3 1015.7226 -0.15253 90284 90284 0 0 0 0 0 0 3502 631;966;1767 226;220;231 226 644;2980 740;741;3389;3390 28408 17633 Mix4_InSol_Tio2_Reinj_1 7978 6177 3622 Mix4_TiO2_Reinj_1_3 8007 P51812;Q15418;Q9UK32 P51812;Q15418;Q9UK32 P51812 >sp|P51812|KS6A3_HUMAN Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens GN=RPS6KA3 PE=1 SV=1;>sp|Q15418|KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens GN=RPS6KA1 PE=1 SV=2;>sp|Q9UK32|KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 OS=Ho 0.495136 0 0.458806 0 3.93447E-26 189.68 0 0 0.465676 0 1.73198E-39 232.03 0 0 0.402537 0 1.28114E-25 177.1 0.495136 0 1.16935E-25 178.7 1 Y DHEKKAYSFCGTV;DQEKKAYSFCGTV 1.73198E-39 232.03 _KApYSFCGTVEYMAPEVVNR_ KAY(0.495)S(0.495)FCGT(0.01)VEYMAPEVVNR KAY(0)S(0)FCGT(-17.07)VEY(-53.3)MAPEVVNR 3 3 767.67417 -0.31586 0 0 0 0 0 0 0 0 3503 665 774 774 2008;2009 2274;2276;2277 18409 11179 Mix4_TiO2_Reinj_1_5 5189 18409 11179 Mix4_TiO2_Reinj_1_5 5189 P54760 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2 0.983578 17.8186 7.43284E-08 -70.6986 1.37452E-38 219.69 1.36612E-07 -68.5762 3.51501E-10 129.8 0.983578 17.8186 4.16059E-48 247.82 0 0 0.00775171 -17.3816 9.58262E-17 142.64 0.393231 2.469 0.000151466 97.062 1 Y NSSDPTYTSSLGG SRC 0.047736 4.16059E-48 247.82 _FLEENSSDPTpYTSSLGGK_ FLEENSSDPT(0.016)Y(0.984)TSSLGGK FLEENS(-115.16)S(-90.71)DPT(-17.82)Y(17.82)T(-37.69)S(-63.52)S(-78.39)LGGK 11 2 1006.4303 0.43578 222770 2.1372 0 0 0 222770 0 0 0 3504 665 590 590 6664 7629 67573 41490 Mix4_TiO2_1_5 6713 67573 41490 Mix4_TiO2_1_5 6713 P54760;P54753 P54760 P54760 >sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens GN=EPHB4 PE=1 SV=2;>sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens GN=EPHB3 PE=1 SV=2 1 74.5546 1 74.5546 3.57769E-13 154.83 0 0 1 Y GHGTKVYIDPFTY ABL 0.01638 3.57769E-13 154.83 _VpYIDPFTYEDPNEAVR_ VY(1)IDPFTYEDPNEAVR VY(74.55)IDPFT(-74.55)Y(-99.58)EDPNEAVR 2 2 1004.4404 1.0687 61954 61954 0 0 0 0 0 0 3505 719;882 268;264 264 5033 5724 48597 29706 Mix4_TiO2_Reinj_1_4 2763 48597 29706 Mix4_TiO2_Reinj_1_4 2763 P62995;P62995-3;Q13595 P62995;Q13595 Q13595 >sp|P62995|TRA2B_HUMAN Transformer-2 protein homolog beta OS=Homo sapiens GN=TRA2B PE=1 SV=1;>sp|P62995-3|TRA2B_HUMAN Isoform HTRA2-beta3 of Transformer-2 protein homolog beta OS=Homo sapiens GN=TRA2B;>sp|Q13595|TRA2A_HUMAN Transformer-2 protein homolog al 0.768205 8.07622 0.768205 8.07622 0.000770481 79.757 0.407835 0.526513 0.770817 0.5602 2 Y RRSPSPYYSRGGY;RRSPSPYYSRYRS 0.000770481 79.757 _RRSPpSPpYYSR_ RRS(0.072)PS(0.932)PY(0.768)Y(0.058)S(0.169)R RRS(-11.92)PS(11.92)PY(8.08)Y(-11.19)S(-8.08)R 7 2 714.79469 -0.39115 3023500 0 0 0 3023500 0 0 0 3506 728 162 162 4401 5006 41816 25738 Mix4_InSol_Tio2_Reinj_1 3463 41818 25745 Mix4_TiO2_Reinj_1_4 3204 P67809 P67809 P67809 >sp|P67809|YBOX1_HUMAN Nuclease-sensitive element-binding protein 1 OS=Homo sapiens GN=YBX1 PE=1 SV=3 0.392834 1.13321 0.221504 -4.33918 9.37071E-08 107.59 0.00732908 -17.7637 9.7034E-13 132.98 0.0302377 -14.2111 2.41233E-12 126.42 0.392834 1.13321 0.000174045 87.687 1 Y RNYQQNYQNSESG 9.7034E-13 132.98 _NYQQNpYQNSESGEKNEGSESAPEGQAQQR_ NYQQNY(0.393)QNS(0.303)ES(0.303)GEKNEGS(0.002)ESAPEGQAQQR NY(-31.36)QQNY(1.13)QNS(-1.13)ES(-1.13)GEKNEGS(-23.87)ES(-39.71)APEGQAQQR 6 3 1113.1257 -0.43951 0 0 0 0 0 0 0 0 0 3507 756 15 15 2760 3145 26132 16151 Mix4_TiO2_1_2 3645 26136 16156 Mix4_TiO2_1_6 4048 Q00535 Q00535 Q00535 >sp|Q00535|CDK5_HUMAN Cell division protein kinase 5 OS=Homo sapiens GN=CDK5 PE=1 SV=3 0.992911 21.7221 0.992911 21.7221 0.00182026 103.55 0.461322 2.33705 0.233363 27.475 0.920337 10.877 0.00146498 100.19 0 0 0.0728382 -10.6926 0.00299627 80.114 0.285015 -1.78569 0.00544742 73.62 1 Y KIGEGTYGTVFKA ALK 0.2 0.00182026 103.55 _IGEGTpYGTVFK_ IGEGT(0.007)Y(0.993)GTVFK IGEGT(-21.72)Y(21.72)GT(-33.84)VFK 6 2 626.28649 0.33778 280620 71573 0 0 209050 0 0 0 3508 782 42 42 370 422;423 3476 2084 Mix4_TiO2_Reinj_1_6 3385 3506 2089 Mix4_InSol_TiO2_1 5071 Q03135 Q03135 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CAV1 PE=1 SV=4 0.714107 5.63848 0.543123 1.65565 7.7388E-06 103.45 0 0 0.714107 5.63848 6.98277E-09 118.33 0 0 0.107307 -8.64455 4.44367E-16 159.12 0.332905 -2.55692 2.17023E-13 154.2 1 Y LSEKQVYDAHTKE 4.44367E-16 159.12 _AM(ox)ADELSEKQVpYDAHTK_ AMADELS(0.195)EKQVY(0.714)DAHT(0.091)K AMADELS(-5.64)EKQVY(5.64)DAHT(-8.95)K 12 3 677.96249 -0.14171 102690 18270 0 0 84419 0 0 0 3509 782 14 14 5301;6818 6036;7802 69122 42380 Mix4_TiO2_Reinj_1_6 4659 69124 42382 Mix4_TiO2_Reinj_1_6 5165 Q03135 Q03135 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CAV1 PE=1 SV=4 0.983418 17.7324 0.0209614 -16.6938 0.00011301 108.46 0 0 0.983418 17.7324 4.38321E-07 132.91 4.46649E-09 -83.4069 2.57439E-06 110.89 1.26767E-06 -58.9655 0.0328815 58.966 1 Y DSEGHLYTVPIRE ABL 0.01638 4.38321E-07 132.91 _YVDSEGHLpYTVPIR_ YVDSEGHLY(0.983)T(0.017)VPIR Y(-101.43)VDS(-52.16)EGHLY(17.73)T(-17.73)VPIR 9 2 864.90328 -0.024097 196490 0 0 0 196490 0 0 0 3510 799 861 861 2445 2772 22989 14375 Mix4_TiO2_Reinj_1_5 5349 22989 14375 Mix4_TiO2_Reinj_1_5 5349 Q05397 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2 0.999651 35.9408 0.0612642 -11.2614 1.70097 27.681 0 0 0.999651 35.9408 0.000441628 80.159 1 Y IGNQHIYQPVGKP ALK 0.2 0.000441628 80.159 _GSIDREDGSLQGPIGNQHIpYQPVGKPDPAAPPK_ GSIDREDGSLQGPIGNQHIY(1)QPVGKPDPAAPPK GS(-40.27)IDREDGS(-35.94)LQGPIGNQHIY(35.94)QPVGKPDPAAPPK 20 4 880.43205 -0.3241 3796200 0 0 0 3796200 0 0 0 3511 799 720 720 4422;4479 5031;5090 42481 26132 Mix4_TiO2_Reinj_1_3 5022 42478 26125 Mix4_TiO2_1_5 4474 Q05397;Q05397-2 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 0.443803 0 0.28674 -3.78706 2.17064E-07 101.51 0.188544 -6.26736 0.0234521 63.294 0.443803 0 8.8028E-05 92.722 0 0 0.0135826 -18.5971 0.0143024 69.709 0.181669 -6.29579 0.0178485 67.223 1 Y KPSRPGYPSPRSS EGFR 0.143838 2.17064E-07 101.51 _QATVSWDSGGSDEAPPKPSRPGpYPSPR_ QAT(0.006)VS(0.006)WDS(0.042)GGS(0.017)DEAPPKPS(0.043)RPGY(0.444)PS(0.444)PR QAT(-19.04)VS(-19.04)WDS(-10.29)GGS(-14.13)DEAPPKPS(-10.17)RPGY(0)PS(0)PR 23 4 727.33308 0.19238 0 0 0 0 0 0 0 0 3512 799 397 397 6013 6856;6857 59417 36065 Mix4_TiO2_Reinj_1_5 6423 59417 36065 Mix4_TiO2_Reinj_1_5 6423 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.737037 9.27032 0.222043 -0.421734 0.000204101 85.223 0 0 0.737037 9.27032 1.49544E-07 104.48 0 0 0.30308 0 0.000263815 81.239 0.55778 6.32762 0.0149515 70.965 1 Y VSETDDYAEIIDE ALK 0.2 1.49544E-07 104.48 _THAVSVSETDDpYAEIIDEEDTYTM(ox)PSTR_ T(0.001)HAVS(0.087)VS(0.087)ET(0.087)DDY(0.737)AEIIDEEDTYTMPSTR T(-27.22)HAVS(-9.27)VS(-9.27)ET(-9.27)DDY(9.27)AEIIDEEDT(-65.99)Y(-77.81)T(-88.49)MPS(-104.48)T(-104.48)R 12 3 1091.1218 0.44254 1446800 0 0 0 1366000 0 0 80796 3513 799 570 570 6758;6759 7732;7733;7734;7735 68560 42077 Mix4_InSol_TiO2_1 4364 68583 42091 Mix4_InSol_Tio2_Reinj_1 3696 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 1 80.4759 3.34436E-05 -43.7248 0.0488772 47.409 0.00185377 -26.3062 0.00252985 74.845 1 80.4759 6.87067E-06 147.27 0.999996 57.1728 2.55156E-06 153.18 1 Y DFGLSRYMEDSTY 2.55156E-06 153.18 _pYMEDSTYYK_ Y(1)MEDSTYYK Y(80.48)MEDS(-80.48)T(-97.37)Y(-97.37)Y(-97.37)K 1 2 640.23306 0.41321 79618 0 0 0 0 0 41702 37917 3514 799 576 576 6758;6759 7732;7733;7734;7735 68580 42088 Mix4_InSol_TiO2_1 3711 68583 42091 Mix4_InSol_Tio2_Reinj_1 3696 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.991829 21.3461 0.965712 19.0446 0.0488772 47.409 0.972958 18.8229 0.00252985 74.845 0.991829 21.3461 6.87067E-06 147.27 0.971143 18.317 2.55156E-06 153.18 1 Y YMEDSTYYKASKG SRC 0.047736 2.55156E-06 153.18 _YMEDSTpYYKASK_ YMEDST(0.007)Y(0.992)Y(0.001)KASK Y(-147.03)MEDS(-50.84)T(-21.35)Y(21.35)Y(-30.48)KAS(-82.5)K 7 2 783.31511 0.50795 1956100 162500 0 0 601030 0 553730 638860 3515 799 577 577 6758;6759 7732;7733;7734;7735 68564 42082 Mix4_InSol_Tio2_Reinj_2 2897 68583 42091 Mix4_InSol_Tio2_Reinj_1 3696 Q05397;Q05397-2;Q05397-3;Q05397-4 Q05397 Q05397 >sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2;>sp|Q05397-2|FAK1_HUMAN Isoform 2 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q05397-3|FAK1_HUMAN Isoform 3 of Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2;>sp|Q0 0.406848 0 0.0120334 -19.0446 0.0488772 47.409 0.0127586 -18.8229 0.00252985 74.845 0.107653 -9.10883 6.87067E-06 147.27 0.406848 0 2.55156E-06 153.18 1 Y MEDSTYYKASKGK 2.55156E-06 153.18 _YMEDSTpYYK_ Y(0.002)MEDS(0.092)T(0.092)Y(0.407)Y(0.407)K Y(-22.43)MEDS(-6.46)T(-6.46)Y(0)Y(0)K 8 2 640.23306 0.50486 0 0 0 0 0 0 0 0 3516 800 646 646 467;468 530;531;532 4382 2638 Mix4_TiO2_Reinj_1_3 9036 4379 2637 Mix4_TiO2_Reinj_1_3 8154 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.51055 1.88804 0.440854 0 0.402048 50.13 0.0105312 -19.5193 0.384689 21.048 0.51055 1.88804 0.000276637 80.407 0 0 0.147897 -6.77739 0.0166001 67.509 0.0213591 -16.5693 0.0408067 48.914 2 Y EKARLSYSDKNLI 0.000276637 80.407 _ARLSpYSDKNLIDSMDQSAFAGFpSFVNPK_ ARLS(0.331)Y(0.511)S(0.158)DKNLIDSMDQS(0.002)AFAGFS(0.998)FVNPK ARLS(-1.89)Y(1.89)S(-5.1)DKNLIDS(-42.63)MDQS(-26.36)AFAGFS(26.36)FVNPK 5 3 1090.1522 0.5716 426210 0 0 0 426210 0 0 0 3517 800 313 313 522;5037;5038;5178 590;591;5729;5730;5894 50141 30645 Mix4_TiO2_1_3 4816 50144 30650 Mix4_TiO2_Reinj_1_3 6623 Q05655 Q05655 Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Homo sapiens GN=PRKCD PE=1 SV=2 0.999999 66.0001 0.999999 66.0001 4.61512E-26 188.69 1.73393E-13 -121.589 1.35227E-33 218.03 0.00989797 -13.9807 3.23377E-10 126 0.00754895 -19.0612 0.00103108 81.288 1 Y SEPVGIYQGFEKK ABL 0.01638 1.35227E-33 218.03 _SDSASSEPVGIpYQGFEK_ SDSASSEPVGIY(1)QGFEK S(-66.06)DS(-66.06)AS(-66.06)S(-66)EPVGIY(66)QGFEK 12 2 940.90113 -0.18331 51291 0.55252 51291 0 0 0 0 0 0 3518 809 938 938 6618 7577 67129 41188 Mix4_TiO2_Reinj_1_5 6564 67129 41188 Mix4_TiO2_Reinj_1_5 6564 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.893265 9.24769 0.893265 9.24769 0.022041 61.501 1 Y VSSTHYYLLPERP 0.022041 61.501 _VSSTHYpYLLPERPSYLER_ VSSTHY(0.106)Y(0.893)LLPERPSYLER VS(-47.24)S(-38.65)T(-34.05)HY(-9.25)Y(9.25)LLPERPS(-48.69)Y(-48.69)LER 7 3 764.03498 -0.67102 240140 0 0 0 240140 0 0 0 3519 809 905 905 6704 7677 68012 41742 Mix4_TiO2_1_5 4136 68012 41742 Mix4_TiO2_1_5 4136 Q07912-3;Q07912 Q07912-3 Q07912-3 >sp|Q07912-3|ACK1_HUMAN Isoform 3 of Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2;>sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3 0.999717 35.4797 0.999717 35.4797 5.27763E-09 164.76 0 0 0 0 0 0 0.99499 22.9802 3.76037E-05 123.81 0.99466 22.7012 0.000381933 106.72 1 Y FASDPKYATPQVI 5.27763E-09 164.76 _pYATPQVIQAPGPR_ Y(1)ATPQVIQAPGPR Y(35.48)AT(-35.48)PQVIQAPGPR 1 2 739.36359 0.33693 292290 178660 0 0 0 0 66343 47280 3520 822 1151 1151 3489 3940 32935 20404 Mix4_TiO2_Reinj_1_1 7340 32937 20407 Mix4_TiO2_Reinj_1_5 7821 Q12769 Q12769 Q12769 >sp|Q12769|NU160_HUMAN Nuclear pore complex protein Nup160 OS=Homo sapiens GN=NUP160 PE=1 SV=3 0.347177 0 5.99454E-05 -42.2222 9.23568E-18 137.66 0 0 0.347177 0 2.30342E-45 197.78 0.118429 -8.09143 9.05204E-18 138.04 1 Y PVSGAVYDRPGAS ABL;EGFR 0.01638 2.30342E-45 197.78 _LIRPEYAWIVQPVpSGAVYDRPGASPK_ LIRPEYAWIVQPVS(0.347)GAVY(0.347)DRPGAS(0.306)PK LIRPEY(-61.67)AWIVQPVS(0)GAVY(0)DRPGAS(-0.55)PK 18 4 738.13102 -0.15113 0 0 0 0 0 0 0 0 3521 885 614 614 6202 7084 61467 37257 Mix4_TiO2_1_5 4875 61468 37258 Mix4_TiO2_Reinj_1_5 5592 Q13615;Q13615-2;Q13615-3 Q13615 Q13615 >sp|Q13615|MTMR3_HUMAN Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3 PE=1 SV=3;>sp|Q13615-2|MTMR3_HUMAN Isoform FYVE-DSP1a of Myotubularin-related protein 3 OS=Homo sapiens GN=MTMR3;>sp|Q13615-3|MTMR3_HUMAN Isoform FYVE-DSP1c of Myotubularin-rela 0.431467 0 0.431467 0 0.00993202 69.053 0.280956 0 0.00522258 74.405 1 Y LPKTRSYDNLTTA ALK 0.2 0.00522258 74.405 _TRpSYDNLTTACDNTVPLASR_ T(0.132)RS(0.431)Y(0.431)DNLT(0.002)T(0.002)ACDNTVPLASR T(-5.13)RS(0)Y(0)DNLT(-22.64)T(-22.64)ACDNT(-61)VPLAS(-69.05)R 4 3 779.01766 1.3424 0 0 0 0 0 0 0 0 3522 889 312 312 2953 3360 28172 17527 Mix4_TiO2_Reinj_1_3 3871 28168 17523 Mix4_TiO2_1_5 3250 Q13627-2;Q13627;Q13627-5;Q9Y463;Q9Y463-3;Q9Y463-2;Q13627-4;Q13627-3 Q13627-2 Q13627-2 >sp|Q13627-2|DYR1A_HUMAN Isoform 1 of Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A;>sp|Q13627|DYR1A_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2;>sp|Q1362 1 82.1444 1 68.6171 4.41492E-06 143.35 0 0 1 82.1444 5.50824E-06 140.06 0 0 1 64.671 0.000123619 123.87 1 88.0166 0.000123619 123.87 1 Y GQRIYQYIQSRFY 4.41492E-06 143.35 _IYQpYIQSR_ IYQY(1)IQSR IY(-89.86)QY(82.14)IQS(-82.14)R 4 2 575.76826 0.34806 22226000 3345400 0 0 14785000 0 3821600 274390 3523 896 114 114 6592 7544 66845 40995 Mix4_TiO2_Reinj_1_4 5386 66845 40995 Mix4_TiO2_Reinj_1_4 5386 Q13882 Q13882 Q13882 >sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens GN=PTK6 PE=1 SV=1 0.909333 10.0465 0 0 0.909333 10.0465 0.0142816 69.23 1 Y EKPSADYVLSVRD EGFR 0.143838 0.0142816 69.23 _VSEKPSADpYVLSVR_ VS(0.001)EKPS(0.09)ADY(0.909)VLSVR VS(-31.12)EKPS(-10.05)ADY(10.05)VLS(-66.33)VR 9 3 543.93431 0.46781 67146 0 0 0 67146 0 0 0 3524 900 870 870 3809 4304 36199 22378 Mix4_TiO2_Reinj_1_5 3475 36197 22376 Mix4_TiO2_Reinj_1_1 3006 Q14004;Q14004-2 Q14004 Q14004 >sp|Q14004|CDK13_HUMAN Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 PE=1 SV=2;>sp|Q14004-2|CDK13_HUMAN Isoform 2 of Cell division protein kinase 13 OS=Homo sapiens GN=CDK13 0.451331 0 0.0760931 -7.42742 0.411077 21.334 0.0515321 -11.5853 0.696314 11.585 0.451331 0 0.00325837 86.413 0 0 0.00853343 -20.4994 0.435486 20.499 0 0 1 Y SEESRPYTNKVIT 0.00325837 86.413 _LYSSEESRPpYTNK_ LY(0.024)S(0.024)S(0.024)EES(0.024)RPY(0.451)T(0.451)NK LY(-12.68)S(-12.68)S(-12.68)EES(-12.68)RPY(0)T(0)NK 10 3 551.91005 -0.030185 0 0 0 0 0 0 0 0 3525 923 224 224 5241;5242 5964;5965;5966 50855 31163 Mix4_TiO2_1_5 7971 50843 31155 Mix4_TiO2_1_5 8347 Q14671;Q14671-2 Q14671 Q14671 >sp|Q14671|PUM1_HUMAN Pumilio homolog 1 OS=Homo sapiens GN=PUM1 PE=1 SV=3;>sp|Q14671-2|PUM1_HUMAN Isoform 2 of Pumilio homolog 1 OS=Homo sapiens GN=PUM1 0.285571 0.844517 0.285571 0.844517 3.28448E-46 213.55 0.00257781 -21.0937 9.10263E-35 186.93 1 Y GVSMVEYVLSSSP 3.28448E-46 213.55 _SESGGLGVSMVEpYVLSSSPGDSCLRK_ SESGGLGVSMVEY(0.286)VLS(0.235)S(0.235)S(0.235)PGDS(0.009)CLRK S(-73.32)ES(-67.35)GGLGVS(-31.09)MVEY(0.84)VLS(-0.84)S(-0.84)S(-0.84)PGDS(-15.07)CLRK 13 3 927.75388 -0.25582 0 0 0 0 0 0 0 0 3526 974 87 87 5990 6830 59180 35964 Mix4_TiO2_Reinj_1_3 6241 59180 35964 Mix4_TiO2_Reinj_1_3 6241 Q15637-6;Q15637-5;Q15637;Q15637-2;Q15637-3;Q15637-4 Q15637-6 Q15637-6 >sp|Q15637-6|SF01_HUMAN Isoform B6 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637-5|SF01_HUMAN Isoform 5 of Splicing factor 1 OS=Homo sapiens GN=SF1;>sp|Q15637|SF01_HUMAN Splicing factor 1 OS=Homo sapiens GN=SF1 PE=1 SV=4;>sp|Q15637-2|SF01_HUMAN Is 0.478268 0 0.0603717 -9.51128 0.000235233 85.61 0.478268 0 3.28186E-07 102.18 2 Y PSPEPIYNSEGKR EGFR;SRC 0.047736 3.28186E-07 102.18 _TGDLGIPPNPEDRpSPSPEPIpYNSEGK_ TGDLGIPPNPEDRS(0.984)PS(0.059)PEPIY(0.478)NS(0.478)EGK T(-102.18)GDLGIPPNPEDRS(17.86)PS(-10.33)PEPIY(0)NS(0)EGK 21 3 976.08964 -0.16488 0 0 0 0 0 0 0 0 3527 991 182 182 2669 3038 24934 15422 Mix4_TiO2_Reinj_1_4 2428 24934 15422 Mix4_TiO2_Reinj_1_4 2428 Q16539;Q16539-2;Q16539-4;Q16539-3 Q16539 Q16539 >sp|Q16539|MK14_HUMAN Mitogen-activated protein kinase 14 OS=Homo sapiens GN=MAPK14 PE=1 SV=3;>sp|Q16539-2|MK14_HUMAN Isoform CSBP1 of Mitogen-activated protein kinase 14 OS=Homo sapiens GN=MAPK14;>sp|Q16539-4|MK14_HUMAN Isoform Exon skip of Mitogen-activa 0.887651 8.97674 0 0 0.887651 8.97674 0.000128513 115.43 1 Y DDEMTGYVATRWY 0.000128513 115.43 _HTDDEM(ox)TGpYVATR_ HTDDEMT(0.112)GY(0.888)VATR HT(-115.43)DDEMT(-8.98)GY(8.98)VAT(-62.63)R 9 2 796.30835 0.56442 67409 0 0 0 67409 0 0 0 3528 1049 370 370 6006 6846 59276 36017 Mix4_InSol_TiO2_2 4288 59285 36026 Mix4_TiO2_Reinj_1_1 4803 Q5T4S7-2;Q5T4S7;Q5T4S7-3;Q5T4S7-4;Q5T4S7-5 Q5T4S7-2 Q5T4S7-2 >sp|Q5T4S7-2|UBR4_HUMAN Isoform 2 of E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4;>sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1;>sp|Q5T4S7-3|UBR4_HUMAN Isoform 3 of E3 ubiquitin-protein ligase UBR4 OS= 0.178708 0 0.00181495 -26.264 8.00277E-24 165.69 0.030914 -7.94555 1.10746 22.641 8.70799E-05 -39.8004 2.88338E-32 181.34 0 0 0.178708 0 7.97195E-05 96.097 8.66157E-05 -33.7433 5.59385E-24 168.78 1 Y SSKEDDYESDAAT EGFR;SRC 0.047736 2.88338E-32 181.34 _TGSTSpSKEDDYESDAATIVQK_ T(0.159)GS(0.159)T(0.159)S(0.159)S(0.179)KEDDY(0.179)ES(0.005)DAAT(0.001)IVQK T(-0.5)GS(-0.5)T(-0.5)S(-0.5)S(0)KEDDY(0)ES(-15.76)DAAT(-22.89)IVQK 11 3 771.33196 0.025218 0 0 0 0 0 0 0 0 3529 1071 493 493 2358 2668 21829 13567 Mix4_TiO2_Reinj_1_5 4526 21829 13567 Mix4_TiO2_Reinj_1_5 4526 Q63HR2-4;Q63HR2;Q63HR2-6;Q63HR2-3;Q63HR2-5;Q63HR2-2 Q63HR2-4 Q63HR2-4 >sp|Q63HR2-4|TENC1_HUMAN Isoform 4 of Tensin-like C1 domain-containing phosphatase OS=Homo sapiens GN=TENC1;>sp|Q63HR2|TENC1_HUMAN Tensin-like C1 domain-containing phosphatase OS=Homo sapiens GN=TENC1 PE=1 SV=2;>sp|Q63HR2-6|TENC1_HUMAN Isoform 6 of Tensin- 0.999986 48.4845 0.990932 20.3854 0.744909 20.385 0.999986 48.4845 5.87245E-20 183.06 0 0 0 0 1 Y PLDGSPYAQVQRP ALK 0.2 5.87245E-20 183.06 _GPLDGSPpYAQVQRPPR_ GPLDGSPY(1)AQVQRPPR GPLDGS(-48.48)PY(48.48)AQVQRPPR 8 2 909.43835 0.073115 569380 75177 0 0 494210 0 0 0 3530 1132 293 293 2685 3058 25222 15576 Mix4_InSol_TiO2_1 5583 25238 15592 Mix4_TiO2_Reinj_1_5 5211 Q6ZSR9 Q6ZSR9 Q6ZSR9 >sp|Q6ZSR9|YJ005_HUMAN Uncharacterized protein FLJ45252 OS=Homo sapiens PE=1 SV=2 0.499899 0 0.164369 -7.06195 4.86954E-26 183.16 0 0 0.0694731 -11.2691 1.04173E-38 215.07 0.499899 0 9.83999E-22 172.26 0.499862 0 2.59372E-22 174.98 1 Y SKYSRHYSPEDEP 1.04173E-38 215.07 _HpYSPEDEPSPEAQPIAAYK_ HY(0.5)S(0.5)PEDEPSPEAQPIAAYK HY(0)S(0)PEDEPS(-33.94)PEAQPIAAY(-110.9)K 2 3 736.98769 -0.49476 0 0 0 0 0 0 0 0 3531 1148;1149 389;389 389 2055;2056;4869;4870 2329;2330;5535;5536 18867 11518 Mix4_InSol_TiO2_2 3828 18853 11511 Mix4_TiO2_1_3 4359 Q7KZI7-13;Q7KZI7-14 Q7KZI7-13;Q7KZI7-14 Q7KZI7-14 >sp|Q7KZI7-13|MARK2_HUMAN Isoform 13 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2;>sp|Q7KZI7-14|MARK2_HUMAN Isoform 14 of Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 0.420933 0 0.313615 0 1.99861E-16 168.39 0 0 0.162709 -3.31612 3.95798E-16 160.94 0.420933 0 1.86764E-15 146.07 0.131562 -4.15141 4.84304E-06 104.53 1 Y IPTSNSYSKKTQS 1.99861E-16 168.39 _FSDQAGPAIPTSNSpYSKK_ FS(0.001)DQAGPAIPT(0.022)S(0.022)NS(0.113)Y(0.421)S(0.421)KK FS(-24.75)DQAGPAIPT(-12.85)S(-12.85)NS(-5.71)Y(0)S(0)KK 15 2 989.45132 0.092648 0 0 0 0 0 0 0 0 3532 1296 845 845 1653 1856;1858 15236 9193 Mix4_TiO2_1_5 8331 15239 9196 Mix4_TiO2_Reinj_1_6 7597 Q8TD19 Q8TD19 Q8TD19 >sp|Q8TD19|NEK9_HUMAN Serine/threonine-protein kinase Nek9 OS=Homo sapiens GN=NEK9 PE=1 SV=2 0.292172 0.243862 0.292172 0.243862 0.271442 65.199 0.0139958 -11.9715 0.270434 65.253 0.00174799 -24.3627 2.75295E-11 125.74 0.174535 -0.447799 0.0354649 77.845 1 Y EKDTLPYEELQGL ALK 0.2 2.75295E-11 125.74 _ELENAEFIPM(ox)PDSPSPLSAAFSESEKDTLPpYEELQGLK_ ELENAEFIPMPDS(0.276)PS(0.276)PLS(0.039)AAFS(0.039)ES(0.039)EKDT(0.039)LPY(0.292)EELQGLK ELENAEFIPMPDS(-0.24)PS(-0.24)PLS(-8.76)AAFS(-8.76)ES(-8.76)EKDT(-8.76)LPY(0.24)EELQGLK 31 4 1076.9985 0.33684 0 0 0 0 0 0 0 0 0 3533 1320 309 309 1586 1780 14547 8829 Mix4_InSol_Tio2_Reinj_1 3467 14549 8831 Mix4_TiO2_Reinj_1_5 3296 Q8WWM7-3;Q8WWM7;Q8WWM7-2;Q8WWM7-4;Q8WWM7-5;Q8WWM7-6;Q8WWM7-7 Q8WWM7-3 Q8WWM7-3 >sp|Q8WWM7-3|ATX2L_HUMAN Isoform A2D-C of Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L;>sp|Q8WWM7|ATX2L_HUMAN Ataxin-2-like protein OS=Homo sapiens GN=ATXN2L PE=1 SV=2;>sp|Q8WWM7-2|ATX2L_HUMAN Isoform A2D-B of Ataxin-2-like protein OS=Homo sapiens GN=AT 0.878517 9.25987 0.171881 -4.45934 0.464591 17.478 0.154805 -5.22468 0.00758084 62.219 0 0 0.878517 9.25987 0.197605 31.798 1 Y IESSPQYRLRIAM 0.00758084 62.219 _EIESSPQpYR_ EIES(0.017)S(0.104)PQY(0.879)R EIES(-17.05)S(-9.26)PQY(9.26)R 8 2 594.75027 0.7584 52798 0 0 0 0 0 0 52798 3534 1325 4111 4111 4893 5564 46993 28743 Mix4_TiO2_Reinj_1_1 7774 46993 28743 Mix4_TiO2_Reinj_1_1 7774 Q8WXH0-2;Q8WXH0;Q8WXH0-7 Q8WXH0-2 Q8WXH0-2 >sp|Q8WXH0-2|SYNE2_HUMAN Isoform 2 of Nesprin-2 OS=Homo sapiens GN=SYNE2;>sp|Q8WXH0|SYNE2_HUMAN Nesprin-2 OS=Homo sapiens GN=SYNE2 PE=1 SV=3;>sp|Q8WXH0-7|SYNE2_HUMAN Isoform Gamma of Nesprin-2 OS=Homo sapiens GN=SYNE2 0.333333 0 0 0 0.333333 0 2.47399E-07 115.64 1 Y RRGSMSYLAAVEE 2.47399E-07 115.64 _RGpSM(ox)SYLAAVEEEVEESSVK_ RGS(0.333)MS(0.333)Y(0.333)LAAVEEEVEESSVK RGS(0)MS(0)Y(0)LAAVEEEVEES(-115.64)S(-115.64)VK 6 3 766.00653 0.36754 0 0 0 0 0 0 0 0 3535 1337 1316 1316 2549;2550 2894;2895 23844 14801 Mix4_TiO2_1_5 3581 23859 14817 Mix4_TiO2_Reinj_1_5 4020 Q92538 Q92538 Q92538 >sp|Q92538|GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 0.563147 1.59333 0.563147 1.59333 0.00384171 79.117 0 0 0.333281 0 2.70746E-09 130.01 0 0 0.000806759 -30.7848 0.47153 30.785 0.00167683 -27.4868 0.574289 27.487 1 Y VSLDRGYTSDSEV SRC 0.047736 2.70746E-09 130.01 _GpYTSDSEVYTDHGR_ GY(0.563)T(0.047)S(0.39)DSEVYTDHGR GY(1.59)T(-10.82)S(-1.59)DS(-41.92)EVY(-76.88)T(-79.12)DHGR 2 2 833.82268 0.18373 73190 73190 0 0 0 0 0 0 3536 1352 382 382 6668 7634 67604 41505 Mix4_TiO2_Reinj_1_4 3590 67601 41500 Mix4_TiO2_1_3 2931 Q92630;Q92630-2;Q9NR20;Q9NR20-2 Q92630 Q92630 >sp|Q92630|DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2 PE=1 SV=3;>sp|Q92630-2|DYRK2_HUMAN Isoform 2 of Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2;>sp|Q9NR20|DY 0.995176 23.1461 0.993536 21.8674 0.000162288 119.41 0 0 0.995176 23.1461 0.00103593 110.87 0 0 0 0 1 Y HQRVYTYIQSRFY 0.000162288 119.41 _VYTpYIQSR_ VYT(0.005)Y(0.995)IQSR VY(-59.86)T(-23.15)Y(23.15)IQS(-69.38)R 4 2 555.25499 0.44584 2057500 423510 0 0 1634000 0 0 0 3537 1412 231 231 2668 3037 24929 15421 Mix4_TiO2_Reinj_1_4 6982 24929 15421 Mix4_TiO2_Reinj_1_4 6982 Q96IF1 Q96IF1 Q96IF1 >sp|Q96IF1|JUB_HUMAN Protein ajuba OS=Homo sapiens GN=JUB PE=1 SV=1 0.466661 0 0 0 0 0 0.466661 0 0.000228459 85.991 1 Y QESRHSYPPALGS 0.000228459 85.991 _HpSYPPALGSPGALAGAGVGAAGPLER_ HS(0.467)Y(0.467)PPALGS(0.067)PGALAGAGVGAAGPLER HS(0)Y(0)PPALGS(-8.45)PGALAGAGVGAAGPLER 3 3 818.40395 0.0084945 0 0 0 0 0 0 0 0 3538 1417 557 557 5130 5836 49634 30330 Mix4_TiO2_1_5 4804 49634 30330 Mix4_TiO2_1_5 4804 Q96JG6 Q96JG6 Q96JG6 >sp|Q96JG6|CC132_HUMAN Coiled-coil domain-containing protein 132 OS=Homo sapiens GN=CCDC132 PE=1 SV=3 0.788222 5.87353 0.788222 5.87353 0.00544613 76.14 0 0 1 Y KSAYQEYDSDSDV 0.00544613 76.14 _SAYQEpYDSDSDVPEELKR_ SAYQEY(0.788)DS(0.204)DS(0.008)DVPEELKR S(-61.79)AY(-62.6)QEY(5.87)DS(-5.87)DS(-19.97)DVPEELKR 6 3 737.64236 -0.99844 103620 103620 0 0 0 0 0 0 3539 1443 576 576 2385 2699;2701 22161 13826 Mix4_InSol_Tio2_Reinj_2 5135 22165 13832 Mix4_TiO2_Reinj_1_3 6782 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.410562 0 0.00868185 -17.5649 8.68195E-07 108.14 0.0403772 -13.6092 6.7099E-26 161.27 0.190684 -5.11103 0.00178906 85.092 0.410562 0 9.36249E-07 107.35 1 Y NSTPPPYERTRLS EGFR 0.143838 6.7099E-26 161.27 _GQPGNAYDGAGQPSAAYLSMSQGAVANANSpTPPPYER_ GQPGNAY(0.001)DGAGQPS(0.001)AAY(0.002)LS(0.002)MS(0.004)QGAVANANS(0.169)T(0.411)PPPY(0.411)ER GQPGNAY(-28.82)DGAGQPS(-25.53)AAY(-22.99)LS(-23.21)MS(-20.33)QGAVANANS(-3.85)T(0)PPPY(0)ER 35 3 1258.8879 0.04941 0 0 0 0 0 0 0 0 0 3540 1443 226 226 5572 6349 54505 33378 Mix4_InSol_Tio2_Reinj_1 6247 54504 33377 Mix4_InSol_TiO2_1 6285 Q96PK6 Q96PK6 Q96PK6 >sp|Q96PK6|RBM14_HUMAN RNA-binding protein 14 OS=Homo sapiens GN=RBM14 PE=1 SV=2 0.463127 0 0 0 0.333333 0 0.0106926 70.017 0.463127 0 0.0188216 61.916 1 Y SPPRASYVAPLTA EGFR 0.143838 0.0106926 70.017 _SPPRApSYVAPLTAQPATYR_ S(0.074)PPRAS(0.463)Y(0.463)VAPLTAQPATYR S(-7.98)PPRAS(0)Y(0)VAPLT(-61.16)AQPAT(-61.92)Y(-61.92)R 7 3 709.35253 0.33897 0 0 0 0 0 0 0 0 3541 1446 505 505 1277 1440;1441 12038 7376 Mix4_TiO2_Reinj_1_5 3725 12038 7376 Mix4_TiO2_Reinj_1_5 3725 Q96PU5-8;Q96PU5;Q96PU5-7;Q96PU5-5;Q96PU5-6;Q96PU5-2;Q96PU5-4;Q96PU5-3 Q96PU5-8 Q96PU5-8 >sp|Q96PU5-8|NED4L_HUMAN Isoform Nedd4-2a of E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L;>sp|Q96PU5|NED4L_HUMAN E3 ubiquitin-protein ligase NEDD4-like OS=Homo sapiens GN=NEDD4L PE=1 SV=2;>sp|Q96PU5-7|NED4L_HUMAN Isoform NEDD4Lg of E3 u 0.801425 6.5987 0.801425 6.5987 1.72396E-07 114.71 1 Y SPQPSPYNSPKPQ EGFR 0.143838 1.72396E-07 114.71 _DTLSNPQSPQPSPpYNSPKPQHK_ DTLSNPQS(0.002)PQPS(0.175)PY(0.801)NS(0.021)PKPQHK DT(-102.77)LS(-86.21)NPQS(-25.94)PQPS(-6.6)PY(6.6)NS(-15.79)PKPQHK 14 3 843.05862 -0.44456 204240 0 0 0 204240 0 0 0 3542 1524 717 717 406;407 464;465 3865 2312 Mix4_TiO2_Reinj_1_5 4826 3865 2312 Mix4_TiO2_Reinj_1_5 4826 Q9BUJ2;Q9BUJ2-2;Q9BUJ2-4;Q9BUJ2-3;Q9BUJ2-5 Q9BUJ2 Q9BUJ2 >sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1 PE=1 SV=2;>sp|Q9BUJ2-2|HNRL1_HUMAN Isoform Isoform b of Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens GN=HNRNPUL1;>sp|Q9B 0.454842 0 0.333333 0 4.68498E-19 139.13 0 0 0.454842 0 6.30364E-20 154.34 0 0 0.419745 0 0.0721543 77.164 0.32755 0 0.082727 76.776 1 Y PPPPPSYSPARNP 6.30364E-20 154.34 _APQQQPPPQQPPPPQPPPQQPPPPPSpYSPAR_ APQQQPPPQQPPPPQPPPQQPPPPPS(0.09)Y(0.455)S(0.455)PAR APQQQPPPQQPPPPQPPPQQPPPPPS(-7.02)Y(0)S(0)PAR 27 3 1136.889 0.1188 0 0 0 0 0 0 0 0 3543 1530 445 445 6561 7505 66394 40755 Mix4_InSol_TiO2_2 5658 66397 40760 Mix4_TiO2_1_3 6623 Q9BVS4 Q9BVS4 Q9BVS4 >sp|Q9BVS4|RIOK2_HUMAN Serine/threonine-protein kinase RIO2 OS=Homo sapiens GN=RIOK2 PE=1 SV=2 0.501229 0.0426785 0.136561 -8.0089 1.30285E-18 152.95 0.0220802 -16.463 1.76405E-07 104.62 0.501229 0.0426785 0.000165488 87.335 0.203277 -5.92661 0.035651 60 1 Y PAGSDEYEDECPH EGFR 0.143838 1.30285E-18 152.95 _VQGGVPAGSDEpYEDECPHLIALSSLNR_ VQGGVPAGS(0.496)DEY(0.501)EDECPHLIALS(0.001)S(0.001)LNR VQGGVPAGS(-0.04)DEY(0.04)EDECPHLIALS(-26.13)S(-26.13)LNR 12 3 998.44974 -0.45201 181460 0.039924 0 0 0 0 0 181460 0 3544 1551 439 439 5875 6700 57931 35199 Mix4_InSol_TiO2_1 6767 57933 35201 Mix4_TiO2_1_4 5631 Q9BYT3 Q9BYT3 Q9BYT3 >sp|Q9BYT3|STK33_HUMAN Serine/threonine-protein kinase 33 OS=Homo sapiens GN=STK33 PE=1 SV=1 0.328797 0 0.270827 0 0.000115385 91.141 0 0 0.328797 0 0.0306766 61.791 0 0 1 Y NVPDANYTSDEEE SRC 0.047736 0.000115385 91.141 _SYQPWGNVPDANpYTSDEEEEKQSTAYEK_ SYQPWGNVPDANY(0.329)T(0.329)S(0.329)DEEEEKQS(0.009)T(0.002)AY(0.002)EK S(-61.39)Y(-61.39)QPWGNVPDANY(0)T(0)S(0)DEEEEKQS(-15.56)T(-21.91)AY(-21.47)EK 13 3 1115.7963 -0.069977 0 0 0 0 0 0 0 0 3545 1586 195 195 4838 5496;5497;5498 46241 28271 Mix4_TiO2_Reinj_1_1 8348 46222 28252 Mix4_TiO2_Reinj_1_1 7013 Q9H2G2-2;Q9H2G2 Q9H2G2-2 Q9H2G2-2 >sp|Q9H2G2-2|SLK_HUMAN Isoform 2 of STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK;>sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1 0.552491 2.57489 0.361814 0 5.82647E-24 162.75 0.0209188 -14.5096 1.36234E-05 98.42 0.552491 2.57489 7.69469E-25 174.21 0 0 0 0 1 Y SFIGTPYWMAPEV 7.69469E-25 174.21 _RDSFIGTPpYWMAPEVVM(ox)CETSK_ RDS(0.305)FIGT(0.142)PY(0.552)WMAPEVVMCETSK RDS(-2.57)FIGT(-5.9)PY(2.57)WMAPEVVMCET(-43.39)S(-43.39)K 9 3 900.72298 0.79488 91632 0 0 0 91632 0 0 0 3546 1592 361 361 601 692 5745 3394 Mix4_TiO2_1_5 2848 5748 3398 Mix4_TiO2_Reinj_1_5 3504 Q9H2X6;Q9H2X6-3;Q9H2X6-2;Q86Z02;Q86Z02-2 Q9H2X6 Q9H2X6 >sp|Q9H2X6|HIPK2_HUMAN Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2 PE=1 SV=2;>sp|Q9H2X6-3|HIPK2_HUMAN Isoform 3 of Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2;>sp|Q9H2X6-2|HIPK2_HUMAN Isoform 2 of Homeodomain-int 0.999842 38.0599 0.999842 38.0599 0.0026602 103.72 0 0 0.992675 21.6279 0.00428514 112.75 0 0 0.991749 21.1736 0.00187381 99.345 0.99962 34.5805 0.00428514 112.75 1 Y KAVCSTYLQSRYY EGFR 0.143838 0.00428514 112.75 _AVCSTpYLQSR_ AVCSTY(1)LQSR AVCS(-58.91)T(-38.06)Y(38.06)LQS(-66.14)R 6 2 632.77322 0.63639 1898500 132890 0 0 806870 0 436980 521770 3547 1663 1012 1012 6067 6921 59908 36345 Mix4_TiO2_Reinj_1_1 2817 59900 36321 Mix4_InSol_Tio2_Reinj_1 3605 Q9NSY1;Q5H9B9 Q9NSY1 Q9NSY1 >sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2;>sp|Q5H9B9|BM2KL_HUMAN Putative BMP-2-inducible kinase-like protein OS=Homo sapiens GN=BMP2KL PE=5 SV=2 0.446244 0 0.322634 -2.82139 0.162335 33.554 0.0722411 -10.9873 0.0638794 44.519 0.446244 0 0.00776395 67.92 0 0 0.256827 -2.07758 0.600517 7.6027 0.230837 -0.869275 0.00429296 76.459 1 Y KTLKPTYRTPERA 0.00429296 76.459 _TLKPTpYRTPER_ TLKPT(0.108)Y(0.446)RT(0.446)PER T(-46.23)LKPT(-6.18)Y(0)RT(0)PER 6 3 481.24482 0.077228 0 0 0 0 0 0 0 0 3548 1680 341 341 5321 6057 51636 31609 Mix4_InSol_Tio2_Reinj_1 5537 51636 31609 Mix4_InSol_Tio2_Reinj_1 5537 Q9NWQ8 Q9NWQ8 Q9NWQ8 >sp|Q9NWQ8|PAG1_HUMAN Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 OS=Homo sapiens GN=PAG1 PE=1 SV=2 0.683474 6.9275 0 0 0 0 0.683474 6.9275 0.014709 62.926 1 Y TVPESTYTSIQGD ALK 0.2 0.014709 62.926 _SGQSLTVPESTpYTSIQGDPQR_ SGQSLTVPES(0.029)T(0.139)Y(0.683)T(0.139)S(0.01)IQGDPQR S(-62.79)GQS(-62.93)LT(-62.79)VPES(-13.71)T(-6.93)Y(6.93)T(-6.93)S(-18.32)IQGDPQR 12 2 1166.0287 0.050734 37894 0 0 0 0 0 0 37894 3549 1687 49 49 5637;5638;6794;6795 6422;6423;7773;7775 55064 33696 Mix4_InSol_TiO2_2 3824 55024 33680 Mix4_InSol_Tio2_Reinj_1 5297 Q9NX63 Q9NX63 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial OS=Homo sapiens GN=CHCHD3 PE=1 SV=1 0.717343 5.36029 0.320372 -0.489651 1.13428E-12 174.16 0.00381825 -24.1647 0.0175553 66.707 0.253969 -2.86154 6.9551E-12 165.07 0.438076 -1.05748 0.0856368 51.706 0.717343 5.36029 3.20897E-31 198.49 0.402041 4.83762 1.43592E-38 219.09 1 Y GSKSQRYSGAYGA 1.43592E-38 219.09 _SQRpYSGAYGASVSDEELKR_ S(0.062)QRY(0.717)S(0.209)GAY(0.012)GASVSDEELKR S(-10.66)QRY(5.36)S(-5.36)GAY(-17.69)GAS(-48.86)VS(-48.86)DEELKR 4 3 728.33034 -0.074226 31164 0.14407 0 0 0 0 0 31164 0 3550 1687 53 53 5637;5638;6794;6795 6422;6423;7773;7775 55067 33699 Mix4_TiO2_1_6 3415 55024 33680 Mix4_InSol_Tio2_Reinj_1 5297 Q9NX63 Q9NX63 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial OS=Homo sapiens GN=CHCHD3 PE=1 SV=1 0.938821 12.5487 0.938821 12.5487 1.13428E-12 174.16 3.87801E-07 -64.0973 0.0175553 66.707 0.168919 -6.82563 6.9551E-12 165.07 0.00437902 -23.5095 0.0856368 51.706 0.0245064 -11.2278 3.20897E-31 198.49 0.33866 -2.55307 1.43592E-38 219.09 1 Y QRYSGAYGASVSD 1.43592E-38 219.09 _SQRYSGApYGASVSDEELKR_ S(0.001)QRY(0.007)S(0.052)GAY(0.939)GAS(0.002)VSDEELKR S(-31.79)QRY(-21.51)S(-12.55)GAY(12.55)GAS(-27.38)VS(-71.3)DEELKR 8 3 728.33034 0.011607 91429 0.42269 91429 0 0 0 0 0 0 3551 1699 892 892 3807 4302 36167 22365 Mix4_TiO2_1_5 2851 36166 22364 Mix4_TiO2_1_5 2849 Q9NYV4-2;Q9NYV4 Q9NYV4-2 Q9NYV4-2 >sp|Q9NYV4-2|CDK12_HUMAN Isoform 2 of Cell division protein kinase 12 OS=Homo sapiens GN=CDK12;>sp|Q9NYV4|CDK12_HUMAN Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=2 0.344098 0 0.344098 0 0.0004559 104.18 0 0 0.311353 -0.351956 0.00269506 89.051 0 0 0 0 0.152303 -5.0096 0.860187 5.9849 1 Y SEESRPYTNKVIT 0.0004559 104.18 _LYNSEESRPpYTNK_ LY(0.104)NS(0.104)EES(0.104)RPY(0.344)T(0.344)NK LY(-5.2)NS(-5.2)EES(-5.2)RPY(0)T(0)NK 10 3 560.91369 0.31554 0 0 0 0 0 0 0 0 3552 1804 249 249 5755;5756 6558;6559 56587 34544 Mix4_TiO2_1_3 3944 56589 34546 Mix4_TiO2_Reinj_1_3 4590 Q9UPT5;Q9UPT5-1;Q9UPT5-2;Q9UPT5-4 Q9UPT5 Q9UPT5 >sp|Q9UPT5|EXOC7_HUMAN Exocyst complex component 7 OS=Homo sapiens GN=EXOC7 PE=1 SV=3;>sp|Q9UPT5-1|EXOC7_HUMAN Isoform 1 of Exocyst complex component 7 OS=Homo sapiens GN=EXOC7;>sp|Q9UPT5-2|EXOC7_HUMAN Isoform 2 of Exocyst complex component 7 OS=Homo sapie 0.5 0 0.5 0 0.00144334 87.612 0 0 0.499751 0 4.36881E-06 109.84 0.000987356 -30.051 0.0133391 70.357 0.00295108 -25.2694 0.139749 43.475 1 Y SSSGVPYSPAIPN 4.36881E-06 109.84 _SSSSSGVPpYSPAIPNKR_ SSSSSGVPY(0.5)S(0.5)PAIPNKR S(-75.35)S(-75.35)S(-75.35)S(-74.29)S(-69.89)GVPY(0)S(0)PAIPNKR 9 3 605.28752 -0.5493 102970 102970 0 0 0 0 0 0 3553 1809 159 159 5395 6140 52532 32118 Mix4_TiO2_1_3 3402 52532 32118 Mix4_TiO2_1_3 3402 Q9UPZ9;Q9UPZ9-2 Q9UPZ9 Q9UPZ9 >sp|Q9UPZ9|ICK_HUMAN Serine/threonine-protein kinase ICK OS=Homo sapiens GN=ICK PE=1 SV=1;>sp|Q9UPZ9-2|ICK_HUMAN Isoform 2 of Serine/threonine-protein kinase ICK OS=Homo sapiens GN=ICK 0.999847 39.4618 0.999847 39.4618 0.00746205 77.816 0.999658 35.7374 0.00807324 76.712 2 Y KPPYTDYVSTRWY 0.00746205 77.816 _SKPPYpTDpYVSTR_ SKPPY(0.005)T(0.995)DY(1)VSTR S(-73.99)KPPY(-22.87)T(22.87)DY(39.46)VS(-44.03)T(-64.51)R 8 2 787.3204 0.15983 1281100 270590 0 0 1010500 0 0 0 3554 1831 240 240 455 517 4225 2534 Mix4_TiO2_1_3 6150 4229 2540 Mix4_TiO2_Reinj_1_3 6922 Q9Y2U5 Q9Y2U5 Q9Y2U5 >sp|Q9Y2U5|M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens GN=MAP3K2 PE=1 SV=2 0.5 0 0.5 0 0.000303346 88.346 0 0 0.112358 -8.97633 5.9003E-07 106.45 0.224675 -5.37887 0.00146858 78.472 0.491777 -0.139917 0.00182432 78.055 1 Y MPRAQSYPDNHQE 5.9003E-07 106.45 _AQpSYPDNHQEFSDYDNPIFEK_ AQS(0.5)Y(0.5)PDNHQEFSDYDNPIFEK AQS(0)Y(0)PDNHQEFS(-58.96)DY(-77.6)DNPIFEK 4 3 875.35862 -0.85196 2515700 3.6015 2515700 0 0 0 0 0 0 3555 1854 187 187 688 790 6628 3924 Mix4_InSol_TiO2_3 3053 6640 3947 Mix4_TiO2_Reinj_1_4 5240 Q9Y478 Q9Y478 Q9Y478 >sp|Q9Y478|AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens GN=PRKAB1 PE=1 SV=4 0.403833 1.11602 0.332758 0 5.81287E-12 123.9 0.118758 -6.76302 2.30012E-12 132.05 0.403833 1.11602 6.88511E-05 94.055 0.240631 0 0.173024 55.494 1 Y SSPPGPYHQEPYV 2.30012E-12 132.05 _CSDVSELSSSPPGPpYHQEPYVCKPEER_ CS(0.03)DVS(0.029)ELS(0.085)S(0.312)S(0.123)PPGPY(0.404)HQEPY(0.017)VCKPEER CS(-11.24)DVS(-11.49)ELS(-6.78)S(-1.12)S(-5.16)PPGPY(1.12)HQEPY(-13.76)VCKPEER 15 3 1072.1213 -0.37226 0 0 0 0 0 0 0 0 3556 1920 1523 1523 2951 3358 28155 17509 Mix4_TiO2_Reinj_1_1 2022 28155 17509 Mix4_TiO2_Reinj_1_1 2022 REV__Q14571 REV__Q14571 REV__Q14571 >sp|Q14571|ITPR2_HUMAN Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens GN=ITPR2 PE=1 SV=2 0.999777 36.6226 0.999777 36.6226 0.00557958 82.891 0 0 1 Y IKEVRIYNNKSNS 0.00557958 82.891 _IpYNNKSNSDIQK_ IY(1)NNKSNSDIQK IY(36.62)NNKS(-36.62)NS(-52.52)DIQK 2 2 752.3456 1.4649 440510 0 0 0 440510 0 0 0 +