Study Info
INDA Accessions: INRP000605
INSDC Accessions: ERP190748, PRJEB110023
- Title: Characterization of the circulating clinical Isolate of Dengue virus
- Data Type : Whole Genome Sequencing
- Descriptive Title: Whole Genome Sequencing of clinical Isolate of Dengue virus
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Organism:
Scientific Name(Taxon Id): dengue virus type 1 (11053) Common Name:
Scientific Name(Taxon Id): dengue virus type 1 (11060) Common Name:
Scientific Name(Taxon Id): dengue virus type 1 (11069) Common Name:
Scientific Name(Taxon Id): dengue virus type 1 (11070) Common Name:
Other Info
- Abstract: Dengue is the most important mosquito borne disease caused by the dengue virus Affecting 400 million world population every year mainly in the tropical and subtropical regions where India is contributing approximately 35 percent of total cases DENV has four serotypes 1 to 4 belonging to the Flaviviridae family and it has a positive sense single stranded RNA genome of approximately 11 Kilobases Replication of the DENV genome is by RNA dependent RNA polymerase encoded by NS5 RdRp of RNA viruses are error prone due to lack of proof reading activity and results in continuous accumulation of mutations in the viral genome Accumulation of mutation leads to genetic and antigenic diversity within and across DENV serotypes which may also contribute to the emergence of new virulent strains There have been very minimal efforts towards characterizing clinical isolates of DENV To comprehend the genetic and antigenic diversity in comparison to previously reported dengue viruses and to identify the novel mutations in clinical isolates of circulating clinical isolates of dengue virus we have isolated Dengue virus from blood sample of acute dengue patients from the Delhi NCR region in 2025 and performed whole genome sequencing
- Linked publications:
- Center Name: Chandan Kumar Verma1, Anchal Raj1, Megha Brijwal2, Shailendra Mani1, Jayanta Bhattacharya1 and Sankar Bhattacharyya1 1Center of Virus Research, Therapeutics and Vaccines, BRIC-Translational Health Science and Technology Institute, Faridabad 121001 (Haryana), Delhi-NCR, India. 2. Department of Microbiology, All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi - 110029, Delhi, India
- Number of Base(Total) Mbp: 0
- Size in bytes(Total):
- Number of sample:
- Number of Runs:
- Number of Sequences:
- Number of Assembly:
- Number of Variant files:
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