S.No	Sample ID	Sample Name	Study ID	Biological Replicate	Collection Date	Disease	Disease Staging	Geographical Location (Country and/or Sea)	Geographical Location (Region and Locality)	Infection	Isolate	Isolation Source	Phenotype	Sample Extraction Protocol	Sample Preparation Protocol	Sample Type	Tissue
1	IADA-SMszhwtfr8	Uncomplicated_MalariaSample_1	IADA-ST0pe1zmfe	1 of 6	NA	Malaria	Uncomplicated	India	Bikaner, Rajasthan	Plasmodium falciparum	Uncomplicated_MalariaSample_1	Venous blood sample from malaria patient (enriched)	Uncomplicated Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
2	IADA-SMcbmxhv58	Uncomplicated_MalariaSample_2	IADA-ST0pe1zmfe	2 of 6	NA	Malaria	Uncomplicated	India	Bikaner, Rajasthan	Plasmodium falciparum	Uncomplicated_MalariaSample_2	Venous blood sample from malaria patient (enriched)	Uncomplicated Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
3	IADA-SMr1aoqfvb	Uncomplicated_MalariaSample_3	IADA-ST0pe1zmfe	3 of 6	NA	Malaria	Uncomplicated	India	Bikaner, Rajasthan	Plasmodium falciparum	Uncomplicated_MalariaSample_3	Venous blood sample from malaria patient (enriched)	Uncomplicated Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
4	IADA-SMnmyt6rkq	Uncomplicated_MalariaSample_4	IADA-ST0pe1zmfe	4 of 6	NA	Malaria	Uncomplicated	India	Bikaner, Rajasthan	Plasmodium falciparum	Uncomplicated_MalariaSample_4	Venous blood sample from malaria patient (enriched)	Uncomplicated Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
5	IADA-SMvb0yznvm	Uncomplicated_MalariaSample_5	IADA-ST0pe1zmfe	5 of 6	NA	Malaria	Uncomplicated	India	Bikaner, Rajasthan	Plasmodium falciparum	Uncomplicated_MalariaSample_5	Venous blood sample from malaria patient (enriched)	Uncomplicated Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
6	IADA-SMofwflmp8	Uncomplicated_MalariaSample_6	IADA-ST0pe1zmfe	6 of 6	NA	Malaria	Uncomplicated	India	Bikaner, Rajasthan	Plasmodium falciparum	Uncomplicated_MalariaSample_6	Venous blood sample from malaria patient (enriched)	Uncomplicated Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
7	IADA-SMmwdn7teg	Severe_MalariaSample_HepaticDysfunction_1	IADA-ST0pe1zmfe	1 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_1	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
8	IADA-SM7f7r4wp5	Severe_MalariaSample_HepaticDysfunction_2	IADA-ST0pe1zmfe	2 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_2	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
9	IADA-SMbjz54d8e	Severe_MalariaSample_HepaticDysfunction_3	IADA-ST0pe1zmfe	3 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_3	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
10	IADA-SM69yzb0cf	Severe_MalariaSample_HepaticDysfunction_4	IADA-ST0pe1zmfe	4 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_4	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
11	IADA-SMjkgqy9n8	Severe_MalariaSample_HepaticDysfunction_5	IADA-ST0pe1zmfe	5 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_5	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
12	IADA-SMo2zxqh5v	Severe_MalariaSample_HepaticDysfunction_6	IADA-ST0pe1zmfe	6 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_6	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
13	IADA-SM1asce2sl	Severe_MalariaSample_HepaticDysfunction_7	IADA-ST0pe1zmfe	7 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_7	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
14	IADA-SMtfg6n8y4	Severe_MalariaSample_HepaticDysfunction_8	IADA-ST0pe1zmfe	8 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_8	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
15	IADA-SMo6v1iv7g	Severe_MalariaSample_HepaticDysfunction_9	IADA-ST0pe1zmfe	9 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_9	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
16	IADA-SM7t9lg5co	Severe_MalariaSample_HepaticDysfunction_10	IADA-ST0pe1zmfe	10 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_10	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
17	IADA-SMwz9gi1zg	Severe_MalariaSample_HepaticDysfunction_11	IADA-ST0pe1zmfe	11 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_11	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
18	IADA-SMdw6emvup	Severe_MalariaSample_HepaticDysfunction_12	IADA-ST0pe1zmfe	12 of 12	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_HepaticDysfunction_12	Venous blood sample from malaria patient (enriched)	Severe Malaria - Hepatic Dysfunction	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
19	IADA-SM5e30e5tr	Severe_MalariaSample_CerebralMalaria_1	IADA-ST0pe1zmfe	1 of 4	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_CerebralMalaria_1	Venous blood sample from malaria patient (enriched)	Severe Malaria - Cerebral Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
20	IADA-SMkgo9j7wx	Severe_MalariaSample_CerebralMalaria_2	IADA-ST0pe1zmfe	2 of 4	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_CerebralMalaria_2	Venous blood sample from malaria patient (enriched)	Severe Malaria - Cerebral Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
21	IADA-SMbpfdek8a	Severe_MalariaSample_CerebralMalaria_3	IADA-ST0pe1zmfe	3 of 4	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_CerebralMalaria_3	Venous blood sample from malaria patient (enriched)	Severe Malaria - Cerebral Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
22	IADA-SMt6y7z411	Severe_MalariaSample_CerebralMalaria_4	IADA-ST0pe1zmfe	4 of 4	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_CerebralMalaria_4	Venous blood sample from malaria patient (enriched)	Severe Malaria - Cerebral Malaria	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
23	IADA-SMauwxgvx3	Severe_MalariaSample_Thrombocytopenia_1	IADA-ST0pe1zmfe	1 of 6	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_Thrombocytopenia_1	Venous blood sample from malaria patient (enriched)	Severe Malaria - Thrombocytopenia	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
24	IADA-SMi8d1nxf3	Severe_MalariaSample_Thrombocytopenia_2	IADA-ST0pe1zmfe	2 of 6	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_Thrombocytopenia_2	Venous blood sample from malaria patient (enriched)	Severe Malaria - Thrombocytopenia	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
25	IADA-SM6papsxl2	Severe_MalariaSample_Thrombocytopenia_3	IADA-ST0pe1zmfe	3 of 6	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_Thrombocytopenia_3	Venous blood sample from malaria patient (enriched)	Severe Malaria - Thrombocytopenia	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
26	IADA-SMtiqw9ztl	Severe_MalariaSample_Thrombocytopenia_4	IADA-ST0pe1zmfe	4 of 6	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_Thrombocytopenia_4	Venous blood sample from malaria patient (enriched)	Severe Malaria - Thrombocytopenia	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
27	IADA-SM1pzcdvzh	Severe_MalariaSample_Thrombocytopenia_5	IADA-ST0pe1zmfe	5 of 6	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_Thrombocytopenia_5	Venous blood sample from malaria patient (enriched)	Severe Malaria - Thrombocytopenia	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample
28	IADA-SMt3tpj5su	Severe_MalariaSample_Thrombocytopenia_6	IADA-ST0pe1zmfe	6 of 6	NA	Malaria	Severe	India	Bikaner, Rajasthan	Plasmodium falciparum	Severe_MalariaSample_Thrombocytopenia_6	Venous blood sample from malaria patient (enriched)	Severe Malaria - Thrombocytopenia	RNA from enriched blood was isolated using TRIzol as per manufacture's protocols.	Samples were labeled using an Agilent Quick-Amp labeling Kit (p/n5190-0442). Total RNA was reverse transcribed at 40°C using an oligo dT primer tagged to a T7 polymerase promoter and converted to double-stranded cDNA. Synthesized double-stranded cDNA was used as the template for cRNA generation. cRNA was generated by in vitro transcription, and the dye Cy3 CTP(Agilent) was incorporated during this step. The cDNA synthesis and in vitro transcription steps were carried out at 40°C.	Total RNA	Enriched blood sample